[ { "uniprot_canonical_ac": "P47124-1", "uniprot_id": [ { "id": "HOC1_YEAST", "url": "https://www.uniprot.org/uniprot/P47124", "type": "external" } ], "mass": 46297.0, "length": 396, "protein_name": "Putative glycosyltransferase HOC1", "gene_name": "HOC1", "organism": "Yeast", "refseq_name": "alpha-1,6-mannosyltransferase", "refseq_ac": [ { "id": "NP_012609", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012609", "type": "external" } ], "gene_names_uniprotkb": "HOC1; J1830", "gene_names_refseq": "HOC1", "protein_names_uniprotkb": "Putative glycosyltransferase HOC1; 2.4.-.-; M-Pol II subunit Hoc1p; Mannan polymerase II complex HOC1 subunit", "protein_names_refseq": "alpha-1,6-mannosyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR075W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;17322287;24374639;8641269;8840504;9055074;9430634;9434768", "class_list": "glycogene;glycosyltransferase", "function": "The M-Pol II complex possesses alpha-1,6-mannosyltransferase activity and is probably involved in the elongation of the mannan backbone of N-linked glycans on cell wall and periplasmic proteins., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VWP5;E9P8X6", "ec_number_list": [], "go_molecular_function": "GO:0000009 alpha-1,6-mannosyltransferase activity", "go_cellular_component": "GO:0000136 mannan polymerase complex", "go_biological_process": "GO:0000032 cell wall mannoprotein biosynthetic process;GO:0006487 protein N-linked glycosylation;GO:0006080 substituted mannan metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P47124-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47129-1", "uniprot_id": [ { "id": "ACF4_YEAST", "url": "https://www.uniprot.org/uniprot/P47129", "type": "external" } ], "mass": 35521.0, "length": 309, "protein_name": "Assembly-complementing factor 4", "gene_name": "ACF4", "organism": "Yeast", "refseq_name": "Acf4p", "refseq_ac": [ { "id": "NP_012616", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012616", "type": "external" } ], "gene_names_uniprotkb": "ACF4; J1857", "gene_names_refseq": "ACF4", "protein_names_uniprotkb": "Assembly-complementing factor 4", "protein_names_refseq": "Acf4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR083C)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "14562106;14566057;17287358;17322287;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21177495;22218487;23749301;24374639;32597660;33229814;33481703;33491328;34965436;8641269;8840504", "class_list": "", "function": "May be involved in actin cytoskeleton organization and biogenesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 15, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 15, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 15, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 30, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 14, "binding_glycan_count": 0, "secondary_ac_list": "D6VWQ2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 4.0, "record_id": "P47129-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47137-1", "uniprot_id": [ { "id": "YJ66_YEAST", "url": "https://www.uniprot.org/uniprot/P47137", "type": "external" } ], "mass": 32344.0, "length": 282, "protein_name": "Uncharacterized oxidoreductase YJR096W", "gene_name": "J1926", "organism": "Yeast", "refseq_name": "aldo-keto reductase superfamily protein", "refseq_ac": [ { "id": "NP_012630", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012630", "type": "external" } ], "gene_names_uniprotkb": "J1926", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized oxidoreductase YJR096W; 1.-.-.-", "protein_names_refseq": "aldo-keto reductase superfamily protein", "tax_id": 559292, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); ductal carcinoma in situ (Disease Ontology:DOID:0060074); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); castration-resistant prostate carcinoma (Disease Ontology:DOID:0080909); congenital bile acid synthesis defect 2 (Disease Ontology:DOID:0111069); 46,XY sex reversal 8 (Disease Ontology:DOID:0111773); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); pre-eclampsia (Disease Ontology:DOID:10591); leukemia (Disease Ontology:DOID:1240); arteriosclerosis (Disease Ontology:DOID:2349); T-cell acute lymphoblastic leukemia (Disease Ontology:DOID:5603); hepatocellular carcinoma (Disease Ontology:DOID:684); cataract (Disease Ontology:DOID:83); diabetic retinopathy (Disease Ontology:DOID:8947); type 2 diabetes mellitus (Disease Ontology:DOID:9352); diabetic neuropathy (Disease Ontology:DOID:9743); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YJR096W); (R-SCE-193144); (R-SCE-193368); (R-SCE-193775); (R-SCE-193807); (R-SCE-196108); (R-SCE-2162123); (R-SCE-5365859); (R-SCE-5652227); (R-SCE-70221); (R-SCE-9757110)", "pathway_count": 11, "publication_count": 5, "publication_id_list": "14562106;17322287;24374639;33491328;8641269", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 18, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWR5", "ec_number_list": [ { "id": "1.1.1.156", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.156", "type": "external" }, { "id": "1.1.1.117", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.117", "type": "external" }, { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "1.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.-", "type": "external" }, { "id": "1.1.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.2", "type": "external" } ], "go_molecular_function": "GO:0004032 aldose reductase (NADPH) activity;GO:0008106 alcohol dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0034599 cellular response to oxidative stress;GO:0042843 D-xylose catabolic process;GO:0019568 arabinose catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P47137-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47149-1", "uniprot_id": [ { "id": "NNF1_YEAST", "url": "https://www.uniprot.org/uniprot/P47149", "type": "external" } ], "mass": 23640.0, "length": 201, "protein_name": "Kinetochore-associated protein NNF1", "gene_name": "NNF1", "organism": "Yeast", "refseq_name": "MIND complex subunit NNF1", "refseq_ac": [ { "id": "NP_012646", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012646", "type": "external" } ], "gene_names_uniprotkb": "NNF1; J2011", "gene_names_refseq": "NNF1", "protein_names_uniprotkb": "Kinetochore-associated protein NNF1", "protein_names_refseq": "MIND complex subunit NNF1", "tax_id": 559292, "disease": "urinary bladder cancer (Disease Ontology:DOID:11054); bladder carcinoma (Disease Ontology:DOID:4007)", "pathway": " (sce:YJR112W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "12455957;14562106;14602074;14633972;14657030;14690591;17322287;22814378;24374639;8641269;9247195", "class_list": "", "function": "Acts as an essential component of the kinetochore MIND complex, which is required for the spindle checkpoint and kinetochore integrity. MIND plays a role in establishing a bipolar spindle-kinetochore interaction by joining kinetochore subunits contacting DNA to those contacting microtubules. NNF1 is required for a number of nuclear functions. Cells depleted of NNF11 or containing a temperature-sensitive NNF1 mutation have elongated microtubules and become bi- and multinucleate. They also have a fragmented nucleolus and accumulate poly(A)+ RNA inside the nucleus., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWT1;Q06779", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0000776 kinetochore;GO:0000940 outer kinetochore;GO:0000444 MIS12/MIND type complex", "go_biological_process": "GO:0007059 chromosome segregation;GO:0008608 attachment of spindle microtubules to kinetochore;GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P47149-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47190-1", "uniprot_id": [ { "id": "PMT3_YEAST", "url": "https://www.uniprot.org/uniprot/P47190", "type": "external" } ], "mass": 86323.0, "length": 753, "protein_name": "Dolichyl-phosphate-mannose--protein mannosyltransferase 3", "gene_name": "PMT3", "organism": "Yeast", "refseq_name": "dolichyl-phosphate-mannose-protein mannosyltransferase PMT3", "refseq_ac": [ { "id": "NP_014966", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014966", "type": "external" } ], "gene_names_uniprotkb": "PMT3; O6148", "gene_names_refseq": "PMT3", "protein_names_uniprotkb": "Dolichyl-phosphate-mannose--protein mannosyltransferase 3; 2.4.1.109", "protein_names_refseq": "dolichyl-phosphate-mannose-protein mannosyltransferase PMT3", "tax_id": 559292, "disease": "lissencephaly (Disease Ontology:DOID:0050453); Walker-Warburg syndrome (Disease Ontology:DOID:0050560); autosomal recessive limb-girdle muscular dystrophy (Disease Ontology:DOID:0110274); autosomal recessive limb-girdle muscular dystrophy type 2N (Disease Ontology:DOID:0110298); congenital muscular dystrophy-dystroglycanopathy type A2 (Disease Ontology:DOID:0111240); muscular dystrophy-dystroglycanopathy (Disease Ontology:DOID:0112374); muscular dystrophy-dystroglycanopathy type B2 (Disease Ontology:DOID:0112380); muscular dystrophy (Disease Ontology:DOID:9884)", "pathway": " (sce:YOR321W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "12551906;14562106;16847258;21231968;23749301;24374639;33481703;33491328;8585318;8896266;9169874;9184828", "class_list": "glycogene;glycosyltransferase", "function": "Protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity. Forms a heterodimeric complex with PMT5 and more rarely with PMT1 to transfer mannose from Dol-P-mannose to Ser or Thr residues on proteins. Seems to have redundant activity to PMT2., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6W319", "ec_number_list": [ { "id": "2.4.1.109", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.109", "type": "external" } ], "go_molecular_function": "GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0097583 dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt3p dimer complex;GO:0097585 dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt3p dimer complex", "go_biological_process": "GO:0006493 protein O-linked glycosylation;GO:0035269 protein O-linked glycosylation via mannose;GO:1900101 regulation of endoplasmic reticulum unfolded protein response", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P47190-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000010001.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48582-1", "uniprot_id": [ { "id": "BRO1_YEAST", "url": "https://www.uniprot.org/uniprot/P48582", "type": "external" } ], "mass": 97276.0, "length": 844, "protein_name": "Vacuolar-sorting protein BRO1", "gene_name": "BRO1", "organism": "Yeast", "refseq_name": "Bro1p", "refseq_ac": [ { "id": "NP_015241", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015241", "type": "external" } ], "gene_names_uniprotkb": "BRO1; ASI6; LPF2; NPI3; VPS31", "gene_names_refseq": "ASI6; BRO1; LPF2; NPI3; VPS31", "protein_names_uniprotkb": "Vacuolar-sorting protein BRO1; Amino acid sensor-independent protein 6; BCK1-like resistance to osmotic shock protein 1; BRO domain-containing protein 1; Nitrogen permease inactivating protein 3; Vacuolar protein-sorting-associated protein 31", "protein_names_refseq": "Bro1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL084W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "11454748;12062418;12668726;14523026;14562095;14562106;15086794;15326198;18407956;19779198;21126336;23749301;24374639;33229814;33481703;33491328;34965436;8649366;9169875", "class_list": "", "function": "Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles. Fusion between endosomes and the vacuole will then target the cargo proteins to the vacuolar lumen. Acts as an adapter that recruits the DOA4 deubiquitinase to the endosomes, leading to deubiquitination of cargo proteins prior to the lumenal sequestration. Its association to the endosomes depends on SNF7 and its dissociation requires VPS4. Interacts functionally with the Pkc1p-mitogen-activated protein kinase pathway., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 8, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 8, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 8, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D6W3T3;Q02823", "ec_number_list": [], "go_molecular_function": "GO:0035800 deubiquitinase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005829 cytosol;GO:0010008 endosome membrane;GO:1903561 extracellular vesicle", "go_biological_process": "GO:0007034 vacuolar transport;GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0016579 protein deubiquitination;GO:0036010 protein localization to endosome;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "P48582-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50086-1", "uniprot_id": [ { "id": "PSD10_YEAST", "url": "https://www.uniprot.org/uniprot/P50086", "type": "external" } ], "mass": 25616.0, "length": 228, "protein_name": "Probable 26S proteasome regulatory subunit p28", "gene_name": "NAS6", "organism": "Yeast", "refseq_name": "Nas6p", "refseq_ac": [ { "id": "NP_011748", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011748", "type": "external" } ], "gene_names_uniprotkb": "NAS6; G8564", "gene_names_refseq": "NAS6", "protein_names_uniprotkb": "Probable 26S proteasome regulatory subunit p28; Proteasome non-ATPase subunit 6", "protein_names_refseq": "Nas6p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR232W); (R-SCE-8948751)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "14562106;14583612;17322287;19412159;19446322;21126336;24374639;33481703;33491328;8701610;9169869;9714768", "class_list": "", "function": "Acts as a chaperone during the assembly of the 26S proteasome, specifically of the 19S regulatory complex (RC) and appears to have an overlapping role with RPN14., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV12", "ec_number_list": [], "go_molecular_function": "GO:1904855 proteasome regulatory particle binding;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0070682 proteasome regulatory particle assembly", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P50086-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50105-1", "uniprot_id": [ { "id": "TAF4_YEAST", "url": "https://www.uniprot.org/uniprot/P50105", "type": "external" } ], "mass": 42336.0, "length": 388, "protein_name": "Transcription initiation factor TFIID subunit 4", "gene_name": "TAF4", "organism": "Yeast", "refseq_name": "Taf4p", "refseq_ac": [ { "id": "NP_013718", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013718", "type": "external" } ], "gene_names_uniprotkb": "TAF4; MPT1; TAF48; TSG2; YM8270.07", "gene_names_refseq": "MPT1; TAF48; TAF4; TSG2", "protein_names_uniprotkb": "Transcription initiation factor TFIID subunit 4; MPT-1; TAF suppressor gene 2 protein; TAFII-48; TBP-associated factor 48 kDa; TBP-associated factor 4", "protein_names_refseq": "Taf4p", "tax_id": 559292, "disease": "spermatogenic failure 13 (Disease Ontology:DOID:0070182)", "pathway": " (sce:YMR005W); (R-SCE-674695); (R-SCE-73776); (R-SCE-73779); (R-SCE-75953); (R-SCE-76042)", "pathway_count": 6, "publication_count": 29, "publication_id_list": "10788514;11238921;11295558;11473260;12093743;12138208;12516863;14562095;14562106;15665377;17287358;17330950;18407956;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;24374639;24909858;32597660;33481703;33491328;33502312;9169872;9695952", "class_list": "", "function": "Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 28, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZI0", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005669 transcription factor TFIID complex", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter", "synthesized_glycan_count": 0, "hit_score": 3.0, "record_id": "P50105-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50108-1", "uniprot_id": [ { "id": "MNN10_YEAST", "url": "https://www.uniprot.org/uniprot/P50108", "type": "external" } ], "mass": 46748.0, "length": 393, "protein_name": "Probable alpha-1,6-mannosyltransferase MNN10", "gene_name": "MNN10", "organism": "Yeast", "refseq_name": "alpha-1,6-mannosyltransferase", "refseq_ac": [ { "id": "NP_010531", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010531", "type": "external" } ], "gene_names_uniprotkb": "MNN10; BED1; YD8419.12", "gene_names_refseq": "BED1; MNN10; REC41; SLC2", "protein_names_uniprotkb": "Probable alpha-1,6-mannosyltransferase MNN10; 2.4.1.-; Bud emergence delay protein 1; M-Pol II subunit MNN10; Mannan polymerase II complex MNN10 subunit", "protein_names_refseq": "alpha-1,6-mannosyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR245W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10037752;14562106;17322287;24374639;8567719;8991513;9169867", "class_list": "glycogene;glycosyltransferase", "function": "Required for polarized growth and efficient budding., [UniProtKB]; The M-Pol II complex possesses alpha-1,6-mannosyltransferase activity and is probably involved in the elongation of the mannan backbone of N-linked glycans on cell wall and periplasmic proteins., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSM5", "ec_number_list": [], "go_molecular_function": "GO:0000009 alpha-1,6-mannosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0000136 mannan polymerase complex", "go_biological_process": "GO:0000032 cell wall mannoprotein biosynthetic process;GO:0006487 protein N-linked glycosylation;GO:0000917 division septum assembly;GO:0007114 cell budding", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P50108-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50278-1", "uniprot_id": [ { "id": "SOL1_YEAST", "url": "https://www.uniprot.org/uniprot/P50278", "type": "external" } ], "mass": 35653.0, "length": 321, "protein_name": "6-phosphogluconolactonase-like protein 1", "gene_name": "SOL1", "organism": "Yeast", "refseq_name": "Sol1p", "refseq_ac": [ { "id": "NP_014432", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014432", "type": "external" } ], "gene_names_uniprotkb": "SOL1; N3291", "gene_names_refseq": "SOL1", "protein_names_uniprotkb": "6-phosphogluconolactonase-like protein 1", "protein_names_refseq": "Sol1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR034W); (R-SCE-71336)", "pathway_count": 2, "publication_count": 21, "publication_id_list": "11875433;14562095;14562106;15454531;15665377;17287358;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;23749301;24374639;32597660;33481703;33491328;8725220;9169873", "class_list": "", "function": "May be involved in regulation of tRNA subcellular distribution., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1K9", "ec_number_list": [], "go_molecular_function": "GO:0017057 6-phosphogluconolactonase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006409 tRNA export from nucleus;GO:0005975 carbohydrate metabolic process;GO:0009051 pentose-phosphate shunt, oxidative branch", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P50278-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50874-1", "uniprot_id": [ { "id": "ORC5_YEAST", "url": "https://www.uniprot.org/uniprot/P50874", "type": "external" } ], "mass": 55289.0, "length": 479, "protein_name": "Origin recognition complex subunit 5", "gene_name": "ORC5", "organism": "Yeast", "refseq_name": "origin recognition complex subunit 5", "refseq_ac": [ { "id": "NP_014138", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014138", "type": "external" } ], "gene_names_uniprotkb": "ORC5; N0834", "gene_names_refseq": "ORC5", "protein_names_uniprotkb": "Origin recognition complex subunit 5; Origin recognition complex 53 kDa subunit", "protein_names_refseq": "origin recognition complex subunit 5", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL261W); (R-SCE-176187); (R-SCE-68616); (R-SCE-68689); (R-SCE-68962)", "pathway_count": 5, "publication_count": 10, "publication_id_list": "14562106;18006685;19956593;20139071;22814378;24374639;33491328;7579692;9169873;9234673", "class_list": "", "function": "Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication. This subunit is a candidate for the mediation of ATP-dependent binding of ORC to origins. May also be a substrate targeting component of a cullin-RING-based E3 ubiquitin-protein ligase complex RTT101(MMS1-ORC5)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0T2", "ec_number_list": [], "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005656 nuclear pre-replicative complex;GO:0031261 DNA replication preinitiation complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005664 nuclear origin of replication recognition complex", "go_biological_process": "GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication;GO:0006275 regulation of DNA replication;GO:0006270 DNA replication initiation;GO:0030466 silent mating-type cassette heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P50874-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P52867-1", "uniprot_id": [ { "id": "PMT5_YEAST", "url": "https://www.uniprot.org/uniprot/P52867", "type": "external" } ], "mass": 84776.0, "length": 743, "protein_name": "Dolichyl-phosphate-mannose--protein mannosyltransferase 5", "gene_name": "PMT5", "organism": "Yeast", "refseq_name": "putative dolichyl-phosphate-mannose-protein mannosyltransferase PMT5", "refseq_ac": [ { "id": "NP_010190", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010190", "type": "external" } ], "gene_names_uniprotkb": "PMT5; D2399", "gene_names_refseq": "PMT5", "protein_names_uniprotkb": "Dolichyl-phosphate-mannose--protein mannosyltransferase 5; 2.4.1.109", "protein_names_refseq": "putative dolichyl-phosphate-mannose-protein mannosyltransferase PMT5", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL093W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12551906;16847258;24374639;8923743;9169867", "class_list": "glycogene;glycosyltransferase", "function": "Protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity. Forms a heterodimeric complex with PMT3 and more rarely with PMT2 to transfer mannose from Dol-P-mannose to Ser or Thr residues on proteins., [UniProtKB, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6VRQ5;Q92181", "ec_number_list": [ { "id": "2.4.1.109", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.109", "type": "external" } ], "go_molecular_function": "GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0097585 dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt3p dimer complex;GO:0097584 dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt2p dimer complex", "go_biological_process": "GO:0035269 protein O-linked glycosylation via mannose;GO:1900101 regulation of endoplasmic reticulum unfolded protein response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P52867-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P52870-1", "uniprot_id": [ { "id": "SC6B1_YEAST", "url": "https://www.uniprot.org/uniprot/P52870", "type": "external" } ], "mass": 8711.0, "length": 82, "protein_name": "Protein transport protein SBH1", "gene_name": "SBH1", "organism": "Yeast", "refseq_name": "Arf family guanine nucleotide exchange factor SBH1", "refseq_ac": [ { "id": "NP_011011", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011011", "type": "external" } ], "gene_names_uniprotkb": "SBH1; SEB1; YER087BC", "gene_names_refseq": "SBH1; SEB1; YER087C-A", "protein_names_uniprotkb": "Protein transport protein SBH1; Sec61 complex subunit SBH1; Sec61 complex subunit beta", "protein_names_refseq": "Arf family guanine nucleotide exchange factor SBH1", "tax_id": 559292, "disease": "", "pathway": " (sce:YER087C-B)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10611978;10775273;15831493;19795423;19823750;22814378;23237413;23749301;24374639;32597660;33481703;33491328;8740416;8929540;9160745;9169868", "class_list": "", "function": "Part of the Sec61 complex, which is the major component of a channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). The functional states of the translocon complex include co- and post-translational ER import, cotranslational membrane protein integration and retrograde transport of misfolded proteins out of the ER. In the cotranslational pathway, ribosomes synthesizing presecretory proteins are targeted to the translocon by the cytosolic signal recognition particle (SRP) and its ER-localized receptor. The association of the Sec61 complex with the ribosome is mediated by the 28S rRNA of the large ribosomal subunit. SRP-independent post-translational translocation requires the association of additional factors, such as the Sec62/63 complex and KAR2., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D3DLZ4", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:0008320 protein transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane;GO:0005784 Sec61 translocon complex", "go_biological_process": "GO:0031204 post-translational protein targeting to membrane, translocation;GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P52870-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P52891-1", "uniprot_id": [ { "id": "NUP84_YEAST", "url": "https://www.uniprot.org/uniprot/P52891", "type": "external" } ], "mass": 83635.0, "length": 726, "protein_name": "Nucleoporin NUP84", "gene_name": "NUP84", "organism": "Yeast", "refseq_name": "Nup84p", "refseq_ac": [ { "id": "NP_010167", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010167", "type": "external" } ], "gene_names_uniprotkb": "NUP84", "gene_names_refseq": "NUP84", "protein_names_uniprotkb": "Nucleoporin NUP84; Nuclear pore protein NUP84", "protein_names_refseq": "Nup84p", "tax_id": 559292, "disease": "nephrotic syndrome type 11 (Disease Ontology:DOID:0080385); ovarian dysgenesis 6 (Disease Ontology:DOID:0080498); Galloway-Mowat syndrome (Disease Ontology:DOID:0080694); 46 XX gonadal dysgenesis (Disease Ontology:DOID:14450)", "pathway": " (sce:YDL116W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10684247;11823431;12791264;14562106;17563356;19779198;21126336;22814378;24374639;33481703;33491328;8565072;9169867", "class_list": "", "function": "Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. NUP84 is involved in nuclear poly(A)+ RNA export, in NPC assembly and distribution, as well as in nuclear envelope organization., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRN4", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0017056 structural constituent of nuclear pore", "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0005635 nuclear envelope;GO:0005643 nuclear pore;GO:0031965 nuclear membrane;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0031509 subtelomeric heterochromatin formation;GO:0006406 mRNA export from nucleus;GO:0006913 nucleocytoplasmic transport;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P52891-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P52917-1", "uniprot_id": [ { "id": "VPS4_YEAST", "url": "https://www.uniprot.org/uniprot/P52917", "type": "external" } ], "mass": 48172.0, "length": 437, "protein_name": "Vacuolar protein sorting-associated protein 4", "gene_name": "VPS4", "organism": "Yeast", "refseq_name": "AAA family ATPase VPS4", "refseq_ac": [ { "id": "NP_015499", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015499", "type": "external" } ], "gene_names_uniprotkb": "VPS4; CSC1; DID6; END13; GRD13; P9705.10; VPL4; VPT10", "gene_names_refseq": "CSC1; DID6; END13; GRD13; VPL4; VPS4; VPT10", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 4; DOA4-independent degradation protein 6; Protein END13; Vacuolar protein-targeting protein 10", "protein_names_refseq": "AAA family ATPase VPS4", "tax_id": 559292, "disease": "attention deficit hyperactivity disorder (Disease Ontology:DOID:1094)", "pathway": " (sce:YPR173C); (R-SCE-9668328)", "pathway_count": 2, "publication_count": 26, "publication_id_list": "11329380;12953057;14562106;15086794;16505166;16601096;17130288;17330950;17928861;17928862;17949747;18032584;18272179;18280501;18407956;19795423;19823750;21126336;23749301;24374639;32597660;33481703;33491328;9155008;9169875;9606181", "class_list": "", "function": "Involved in the transport of biosynthetic membrane proteins from the prevacuolar/endosomal compartment to the vacuole. Required for multivesicular body (MVB) protein sorting. Catalyzes the ATP-dependent dissociation of class E VPS proteins from endosomal membranes, such as the disassembly of the ESCRT-III complex., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4H4", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0001778 plasma membrane repair;GO:0031468 nuclear membrane reassembly;GO:0036258 multivesicular body assembly;GO:0071985 multivesicular body sorting pathway;GO:0097352 autophagosome maturation", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "P52917-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53010-1", "uniprot_id": [ { "id": "PAN2_YEAST", "url": "https://www.uniprot.org/uniprot/P53010", "type": "external" } ], "mass": 127039.0, "length": 1115, "protein_name": "PAN2-PAN3 deadenylation complex catalytic subunit PAN2", "gene_name": "PAN2", "organism": "Yeast", "refseq_name": "poly(A)-specific ribonuclease", "refseq_ac": [ { "id": "NP_011421", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011421", "type": "external" } ], "gene_names_uniprotkb": "PAN2", "gene_names_refseq": "PAN2", "protein_names_uniprotkb": "PAN2-PAN3 deadenylation complex catalytic subunit PAN2; 3.1.13.4; PAB1P-dependent poly(A)-specific ribonuclease; PAN deadenylation complex subunit 2; Poly(A)-nuclease deadenylation complex subunit 2", "protein_names_refseq": "poly(A)-specific ribonuclease", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL094C); (R-SCE-429947)", "pathway_count": 2, "publication_count": 25, "publication_id_list": "11239395;11953437;1339314;1358757;14562095;14562106;15121841;15169912;15630021;15894541;16940550;18407956;19779198;23749301;24374639;24872509;24880344;33229814;33481703;33491328;8550599;8816488;9169869;9290212;9774670", "class_list": "", "function": "Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenylation-dependent mRNA decaping by DCP1-DCP2 and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails, trimming the tails from their synthesized length to the slightly shorter, apparently messenger-specific length found on newly exported mRNAs. PAN cooperates with protein kinase DUN1 in the regulation of RAD5 mRNA levels and cell survival in response to replicational stress., [UniProtKB, PubMed, PubMed, HAMAP, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 5, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 5, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 5, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 8, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VU51", "ec_number_list": [ { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.1.13.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.4", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003676 nucleic acid binding;GO:0004535 poly(A)-specific ribonuclease activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000932 P-body;GO:0031251 PAN complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0006301 DNA damage tolerance;GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening", "synthesized_glycan_count": 0, "hit_score": 3.2, "record_id": "P53010-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53039-1", "uniprot_id": [ { "id": "YIP1_YEAST", "url": "https://www.uniprot.org/uniprot/P53039", "type": "external" } ], "mass": 27080.0, "length": 248, "protein_name": "Protein transport protein YIP1", "gene_name": "YIP1", "organism": "Yeast", "refseq_name": "transporter YIP1", "refseq_ac": [ { "id": "NP_011688", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011688", "type": "external" } ], "gene_names_uniprotkb": "YIP1", "gene_names_refseq": "YIP1", "protein_names_uniprotkb": "Protein transport protein YIP1; YPT-interacting protein 1", "protein_names_refseq": "transporter YIP1", "tax_id": 559292, "disease": "azoospermia (Disease Ontology:DOID:14227)", "pathway": " (sce:YGR172C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10970842;11278413;11785952;12657649;12802060;15263065;15611160;24374639;9169869;9724632", "class_list": "", "function": "Required for fusion of ER-derived vesicles with the Golgi during ER-to-Golgi protein transport, probably by mediating correct membrane localization of YPT1., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 13, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUV6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0030134 COPII-coated ER to Golgi transport vesicle;GO:0005789 endoplasmic reticulum membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0015031 protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0016192 vesicle-mediated transport;GO:0048280 vesicle fusion with Golgi apparatus", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P53039-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53040-1", "uniprot_id": [ { "id": "TAF6_YEAST", "url": "https://www.uniprot.org/uniprot/P53040", "type": "external" } ], "mass": 57902.0, "length": 516, "protein_name": "SAGA complex/transcription factor TFIID complex subunit TAF6", "gene_name": "TAF6", "organism": "Yeast", "refseq_name": "TATA-binding protein-associated factor TAF6", "refseq_ac": [ { "id": "NP_011403", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011403", "type": "external" } ], "gene_names_uniprotkb": "TAF6; G2985; TAF60", "gene_names_refseq": "TAF60; TAF6", "protein_names_uniprotkb": "SAGA complex/transcription factor TFIID complex subunit TAF6; TAFII-60; TAFII60; TBP-associated factor 60 kDa; TBP-associated factor 6; Transcription initiation factor TFIID subunit 6", "protein_names_refseq": "TATA-binding protein-associated factor TAF6", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL112C); (R-SCE-674695); (R-SCE-6807505); (R-SCE-73776); (R-SCE-73779); (R-SCE-75953); (R-SCE-76042)", "pathway_count": 7, "publication_count": 34, "publication_id_list": "10026213;10788514;10864329;11238921;11295558;11473260;12052880;12093743;12138208;12186975;12446794;12501245;12516863;12840001;14562106;15260971;15448131;15647753;17322287;21734642;22932476;24374639;25216679;28918903;29485702;31969703;33491328;33864814;7667272;9046090;9169869;9674426;9695952;9844639", "class_list": "", "function": "Functions as a component of both the DNA-binding general transcription initiation factor complex TFIID and the transcription coactivator SAGA complex (PubMed:10788514, PubMed:12052880, PubMed:12138208, PubMed:25216679, PubMed:9844639). Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription (PubMed:11238921, PubMed:12516863, PubMed:15448131). SAGA acts as a general cofactor required for essentially all RNA polymerase II transcription (PubMed:10864329, PubMed:25216679, PubMed:9674426). At the promoters, SAGA is required for transcription pre-initiation complex (PIC) recruitment. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (via core/TAF module) and promoter selectivity, interaction with transcription activators (via Tra1/SPT module), and chromatin modification through histone acetylation (via HAT module) and deubiquitination (via DUB module) (PubMed:12501245, PubMed:12840001, PubMed:31969703). SAGA preferentially acetylates histones H3 (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac) and H2B and deubiquitinates histone H2B (PubMed:10026213). SAGA interacts with DNA via upstream activating sequences (UASs) (PubMed:28918903). Also identified in a modified version of SAGA named SALSA or SLIK (PubMed:12186975, PubMed:12446794). The cleavage of SPT7 and the absence of the SPT8 subunit in SLIK neither drive any major conformational differences in its structure compared with SAGA, nor significantly affect HAT, DUB, or DNA-binding activities (PubMed:33864814)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VU35", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0042802 identical protein binding;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005669 transcription factor TFIID complex;GO:0000124 SAGA complex;GO:0046695 SLIK (SAGA-like) complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006325 chromatin organization;GO:0006366 transcription by RNA polymerase II;GO:2000144 positive regulation of DNA-templated transcription initiation", "synthesized_glycan_count": 0, "hit_score": 3.5, "record_id": "P53040-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53067-1", "uniprot_id": [ { "id": "IMB5_YEAST", "url": "https://www.uniprot.org/uniprot/P53067", "type": "external" } ], "mass": 113921.0, "length": 1004, "protein_name": "Importin subunit beta-5", "gene_name": "KAP114", "organism": "Yeast", "refseq_name": "karyopherin KAP114", "refseq_ac": [ { "id": "NP_011273", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011273", "type": "external" } ], "gene_names_uniprotkb": "KAP114; HRC1004", "gene_names_refseq": "KAP114", "protein_names_uniprotkb": "Importin subunit beta-5; 114 kDa karyopherin; Karyopherin subunit beta-5; Karyopherin-114", "protein_names_refseq": "karyopherin KAP114", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL241W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10535958;11309407;14562095;14562106;18086883;22814378;24374639;33481703;33491328;39601790;8750240;9169869", "class_list": "", "function": "Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. Serves a receptor for nuclear localization signals (PubMed:10535958, PubMed:11309407). Mediates the nuclear import of TATA-binding protein (TBP) (PubMed:10535958). Also acts as a nuclear import receptor for histone H2A-H2B dimers; together with co-chaperone NAP1 and Ran-GTP GSP1 it then facilitates the specific and accurate deposition of H2A-H2B into nucleosomes (PubMed:11309407)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV94", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding;GO:0061608 nuclear import signal receptor activity;GO:0000511 H2A-H2B histone complex chaperone activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006334 nucleosome assembly;GO:0006607 NLS-bearing protein import into nucleus;GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P53067-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53091-1", "uniprot_id": [ { "id": "MCM6_YEAST", "url": "https://www.uniprot.org/uniprot/P53091", "type": "external" } ], "mass": 112978.0, "length": 1017, "protein_name": "DNA replication licensing factor MCM6", "gene_name": "MCM6", "organism": "Yeast", "refseq_name": "MCM DNA helicase complex subunit MCM6", "refseq_ac": [ { "id": "NP_011314", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011314", "type": "external" } ], "gene_names_uniprotkb": "MCM6", "gene_names_refseq": "MCM6", "protein_names_uniprotkb": "DNA replication licensing factor MCM6; 3.6.4.12; Minichromosome maintenance protein 6", "protein_names_refseq": "MCM DNA helicase complex subunit MCM6", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL201C); (R-SCE-176187); (R-SCE-68867); (R-SCE-68962); (R-SCE-69052)", "pathway_count": 5, "publication_count": 19, "publication_id_list": "14562106;17330950;18407956;18657510;19779198;19896182;19910535;21070963;21126336;23749301;24374639;32597660;33229814;33481703;33491328;34963704;9154825;9169869;9491083", "class_list": "", "function": "Acts as a component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Once loaded onto DNA, double hexamers can slide on dsDNA in the absence of ATPase activity. Required for the entry in S phase and for cell division., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 33, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VTV3;Q870M9", "ec_number_list": [ { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "5.6.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.4", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" } ], "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003697 single-stranded DNA binding;GO:0017116 single-stranded DNA helicase activity", "go_cellular_component": "GO:0005656 nuclear pre-replicative complex;GO:0031261 DNA replication preinitiation complex;GO:0043596 nuclear replication fork;GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication;GO:0006271 DNA strand elongation involved in DNA replication;GO:0006260 DNA replication;GO:0006270 DNA replication initiation;GO:0000727 double-strand break repair via break-induced replication", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P53091-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53104-1", "uniprot_id": [ { "id": "ATG1_YEAST", "url": "https://www.uniprot.org/uniprot/P53104", "type": "external" } ], "mass": 101717.0, "length": 897, "protein_name": "Serine/threonine-protein kinase ATG1", "gene_name": "ATG1", "organism": "Yeast", "refseq_name": "serine/threonine protein kinase ATG1", "refseq_ac": [ { "id": "NP_011335", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011335", "type": "external" } ], "gene_names_uniprotkb": "ATG1; APG1; AUT3; CVT10; G1615", "gene_names_refseq": "APG1; ATG1; AUT3; CVT10", "protein_names_uniprotkb": "Serine/threonine-protein kinase ATG1; 2.7.11.1; Autophagy protein 3; Autophagy-related protein 1; Cytoplasm to vacuole targeting protein 10", "protein_names_refseq": "serine/threonine protein kinase ATG1", "tax_id": 559292, "disease": "triple-receptor negative breast cancer (Disease Ontology:DOID:0060081)", "pathway": " (sce:YGL180W); (R-SCE-1632852); (R-SCE-8934903)", "pathway_count": 3, "publication_count": 62, "publication_id_list": "10837477;10995454;11309418;11486014;11689437;11904149;12589048;14536056;14562095;14562106;14723849;15665377;16172400;17295840;17330950;17699586;17700056;18077553;18407956;18497569;18701704;18725539;18818209;19684113;19779198;19795423;19823750;20439775;20489023;20855505;20953146;21126336;21228276;21460632;21490424;21576396;21712380;22722939;22768199;22778255;22785534;22885598;22977244;23230142;23382696;23549786;23749301;24374639;24440502;24905091;24909858;28821724;30655342;32597660;33481703;33491328;8224160;8663607;9046087;9169869;9190802;9224897", "class_list": "", "function": "Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (PubMed:18818209, PubMed:21576396, PubMed:22768199, PubMed:23230142). Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates (PubMed:21228276). Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9 (PubMed:14723849, PubMed:20855505, PubMed:24440502, PubMed:24905091). Catalyzes phosphorylation of ATG4, decreasing the interaction between ATG4 and ATG8 and impairing deconjugation of PE-conjugated forms of ATG8 (PubMed:28821724). Finally, ATG1 is also required for the maintenance of cell viability under starvation and for glycogen storage during stationary phase. Plays a role in genome stability through suppression of abnormal mitosis under starvation, and in regulation of filamentous growth., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 58, "reported_mutagensis": 22, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTX3", "ec_number_list": [ { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.1.26.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.26.-", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.67", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005776 autophagosome;GO:0034045 phagophore assembly site membrane", "go_biological_process": "GO:0051365 cellular response to potassium ion starvation;GO:0000045 autophagosome assembly;GO:0010506 regulation of autophagy;GO:0042594 response to starvation;GO:0016236 macroautophagy", "synthesized_glycan_count": 0, "hit_score": 6.3, "record_id": "P53104-1", "record_type": "protein", "filter_code": "0000000.0100111.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53114-1", "uniprot_id": [ { "id": "MED5_YEAST", "url": "https://www.uniprot.org/uniprot/P53114", "type": "external" } ], "mass": 128794.0, "length": 1132, "protein_name": "Mediator of RNA polymerase II transcription subunit 5", "gene_name": "NUT1", "organism": "Yeast", "refseq_name": "Nut1p", "refseq_ac": [ { "id": "NP_011364", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011364", "type": "external" } ], "gene_names_uniprotkb": "NUT1; G1876; MED5", "gene_names_refseq": "MED5; NUT1; SSX4", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 5; Mediator complex subunit 5; Negative regulator of URS2 protein 1", "protein_names_refseq": "Nut1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL151W)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "12191485;14562095;14562106;14623974;15175151;15477388;16002404;16076843;16109375;16263706;16429153;17192271;18407956;19779198;23749301;24374639;30516470;32597660;33491328;8585324;9169869;9671481;9812975", "class_list": "", "function": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTZ9", "ec_number_list": [], "go_molecular_function": "GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0016592 mediator complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006366 transcription by RNA polymerase II;GO:0032968 positive regulation of transcription elongation by RNA polymerase II;GO:0051123 RNA polymerase II preinitiation complex assembly", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P53114-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53146-1", "uniprot_id": [ { "id": "USE1_YEAST", "url": "https://www.uniprot.org/uniprot/P53146", "type": "external" } ], "mass": 28107.0, "length": 245, "protein_name": "Protein transport protein USE1", "gene_name": "USE1", "organism": "Yeast", "refseq_name": "SNAP receptor USE1", "refseq_ac": [ { "id": "NP_011417", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011417", "type": "external" } ], "gene_names_uniprotkb": "USE1; SLT1", "gene_names_refseq": "SLT1; USE1", "protein_names_uniprotkb": "Protein transport protein USE1; SNARE-like tail-anchored protein 1; Unconventional SNARE in the endoplasmic reticulum protein 1", "protein_names_refseq": "SNAP receptor USE1", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL098W); (R-SCE-6811434)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "12853481;12893879;12911815;14562095;14562106;15116429;17322287;19779198;24374639;33491328;34965436;9169869;9290212", "class_list": "", "function": "SNARE required for targeting and fusion of Golgi-derived retrograde transport vesicles with the ER., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VU47", "ec_number_list": [], "go_molecular_function": "GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0098554 cytoplasmic side of endoplasmic reticulum membrane;GO:0005783 endoplasmic reticulum;GO:0031201 SNARE complex;GO:0012508 Golgi to ER transport vesicle membrane", "go_biological_process": "GO:0015031 protein transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0048279 vesicle fusion with endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P53146-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53168-1", "uniprot_id": [ { "id": "DUO1_YEAST", "url": "https://www.uniprot.org/uniprot/P53168", "type": "external" } ], "mass": 27473.0, "length": 247, "protein_name": "DASH complex subunit DUO1", "gene_name": "DUO1", "organism": "Yeast", "refseq_name": "Duo1p", "refseq_ac": [ { "id": "NP_011454", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011454", "type": "external" } ], "gene_names_uniprotkb": "DUO1", "gene_names_refseq": "DUO1", "protein_names_uniprotkb": "DASH complex subunit DUO1; Death upon overproduction protein 1; Outer kinetochore protein DUO1", "protein_names_refseq": "Duo1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL061C)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "11782438;12408861;14562095;14562106;15640796;15664196;16415853;16715078;16777964;17322287;17460120;17643123;18079178;18407956;22218487;22814378;24374639;25236177;33229814;33491328;36701236;9169869;9234674;9817759", "class_list": "", "function": "Component of the DASH complex that connects microtubules with kinetochores and couples microtubule depolymerization to chromosome movement; it is involved in retrieving kinetochores to the spindle poles before their re-orientation on the spindle in early mitosis and allows microtubule depolymerization to pull chromosomes apart and resist detachment during anaphase (PubMed:15664196, PubMed:16415853, PubMed:16777964, PubMed:17460120, PubMed:17643123). Kinetochores, consisting of a centromere-associated inner segment and a microtubule-contacting outer segment, play a crucial role in chromosome segregation by mediating the physical connection between centromeric DNA and microtubules (PubMed:15664196, PubMed:16415853, PubMed:16777964, PubMed:17460120). Kinetochores also serve as an input point for the spindle assembly checkpoint, which delays anaphase until all chromosomes have bioriented on the mitotic spindle (PubMed:12408861, PubMed:9817759). During spindle-kinetochore attachment, kinetochores first attach to the lateral surface of spindle microtubules, which supports the congression of chromosomes toward the middle of the dividing cell; they then slide along towards the spindle pole, a process independent of the DASH complex but requiring the NDC80 complex (PubMed:25236177). When the end of a disassembling microtubule reaches the laterally attached kinetochore, the DASH complex together with the NDC80 complex and STU2 convert lateral attachment to end-on capture to produce a structure that can track with microtubule shortening and sustain attachment when tension is applied across sister kinetochores upon their biorientation (PubMed:15640796, PubMed:15664196, PubMed:25236177). Microtubule depolymerization proceeds by protofilament splaying and induces the kinetochore-attached DASH complex to slide longitudinally, thereby helping to transduce depolymerization energy into pulling forces to disjoin chromatids (PubMed:16415853, PubMed:16777964). Incorrect microtubule attachments are corrected by releasing microubules from the kinetochore through phosphorylation by IPL1 of kinetochore components (PubMed:12408861). Links the microtubule cytoskeleton to chromosomes during interphase (PubMed:36701236). Also contributes to the poleward transport of kinetochores on microtubules following centromeric DNA replication in S-phase (PubMed:18079178)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 7, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 7, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 7, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 6, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "D6VU80", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000922 spindle pole;GO:0005874 microtubule;GO:0072686 mitotic spindle;GO:0042729 DASH complex", "go_biological_process": "GO:0008608 attachment of spindle microtubules to kinetochore;GO:0051301 cell division;GO:0031116 positive regulation of microtubule polymerization;GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore;GO:1990758 mitotic sister chromatid biorientation", "synthesized_glycan_count": 0, "hit_score": 3.3, "record_id": "P53168-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53188-1", "uniprot_id": [ { "id": "CGR1_YEAST", "url": "https://www.uniprot.org/uniprot/P53188", "type": "external" } ], "mass": 14417.0, "length": 120, "protein_name": "rRNA-processing protein CGR1", "gene_name": "CGR1", "organism": "Yeast", "refseq_name": "Cgr1p", "refseq_ac": [ { "id": "NP_011486", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011486", "type": "external" } ], "gene_names_uniprotkb": "CGR1", "gene_names_refseq": "CGR1", "protein_names_uniprotkb": "rRNA-processing protein CGR1; Coiled-coil growth-regulated protein 1", "protein_names_refseq": "Cgr1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL029W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "11116400;11932453;14562095;14562106;15878181;16544271;17322287;24374639;33491328;9169869", "class_list": "", "function": "Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUA9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor", "go_biological_process": "GO:0042254 ribosome biogenesis;GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P53188-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53196-1", "uniprot_id": [ { "id": "RPN14_YEAST", "url": "https://www.uniprot.org/uniprot/P53196", "type": "external" } ], "mass": 46383.0, "length": 417, "protein_name": "26S proteasome regulatory subunit RPN14", "gene_name": "RPN14", "organism": "Yeast", "refseq_name": "Rpn14p", "refseq_ac": [ { "id": "NP_011511", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011511", "type": "external" } ], "gene_names_uniprotkb": "RPN14", "gene_names_refseq": "RPN14", "protein_names_uniprotkb": "26S proteasome regulatory subunit RPN14; Proteasome non-ATPase subunit 14", "protein_names_refseq": "Rpn14p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL004C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;14562106;17322287;17499717;19412159;19446322;19446323;24374639;33491328;9169869", "class_list": "", "function": "Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Is not a genuine component of the 26S proteasome, but an auxiliary factor that interacts with the proteasomal ATPase of 19S regulatory particle (RP). Acts as a chaperone which regulates the highly structured assembly of the 19S regulatory particle. Involved in the substrate specificity of the 26S proteasome and is especially involved in the degradation of ubiquitinated GCN4. May contribute to the stability of the 26S proteasome in some stress conditions., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUD4", "ec_number_list": [], "go_molecular_function": "GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0000502 proteasome complex", "go_biological_process": "GO:0006511 ubiquitin-dependent protein catabolic process;GO:0070682 proteasome regulatory particle assembly", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P53196-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53199-1", "uniprot_id": [ { "id": "ERG26_YEAST", "url": "https://www.uniprot.org/uniprot/P53199", "type": "external" } ], "mass": 38706.0, "length": 349, "protein_name": "Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating", "gene_name": "ERG26", "organism": "Yeast", "refseq_name": "sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating)", "refseq_ac": [ { "id": "NP_011514", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011514", "type": "external" } ], "gene_names_uniprotkb": "ERG26", "gene_names_refseq": "ERG26", "protein_names_uniprotkb": "Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating; 1.1.1.170; C-3 sterol dehydrogenase ERG26; C-4 decarboxylase ERG26; Ergosterol biosynthetic protein 26", "protein_names_refseq": "sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating)", "tax_id": 559292, "disease": "X-linked chondrodysplasia punctata 1 (Disease Ontology:DOID:0060292); CHILD syndrome (Disease Ontology:DOID:0111822); CK syndrome (Disease Ontology:DOID:0111898); Bloch-Sulzberger syndrome (Disease Ontology:DOID:12305); cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YGL001C); (R-SCE-6807047); (R-SCE-6807062)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "11279045;12119386;14562106;15716577;15995173;17322287;24374639;26456460;32679672;9169869;9811880", "class_list": "", "function": "Sterol-4-alpha-carboxylate 3-dehydrogenase; part of the third module of ergosterol biosynthesis pathway that includes the late steps of the pathway (PubMed:15995173, PubMed:9811880). ERG26 is a catalytic component of the C-4 demethylation complex that catalyzes the oxidative decarboxylation that results in a reduction of the 3-beta-hydroxy group at the C-3 carbon to an oxo group (PubMed:9811880). The third module or late pathway involves the ergosterol synthesis itself through consecutive reactions that mainly occur in the endoplasmic reticulum (ER) membrane. Firstly, the squalene synthase ERG9 catalyzes the condensation of 2 farnesyl pyrophosphate moieties to form squalene, which is the precursor of all steroids. Squalene synthase is crucial for balancing the incorporation of farnesyl diphosphate (FPP) into sterol and nonsterol isoprene synthesis. Secondly, the squalene epoxidase ERG1 catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, which is considered to be a rate-limiting enzyme in steroid biosynthesis. Then, the lanosterol synthase ERG7 catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol core. In the next steps, lanosterol is transformed to zymosterol through a complex process involving various demethylation, reduction and desaturation reactions. The lanosterol 14-alpha-demethylase ERG11 (also known as CYP51) catalyzes C14-demethylation of lanosterol to produce 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol, which is critical for ergosterol biosynthesis. The C-14 reductase ERG24 reduces the C14=C15 double bond of 4,4-dimethyl-cholesta-8,14,24-trienol to produce 4,4-dimethyl-cholesta-8,24-dienol. 4,4-dimethyl-cholesta-8,24-dienol is substrate of the C-4 demethylation complex ERG25-ERG26-ERG27 in which ERG25 catalyzes the three-step monooxygenation required for the demethylation of 4,4-dimethyl and 4alpha-methylsterols, ERG26 catalyzes the oxidative decarboxylation that results in a reduction of the 3-beta-hydroxy group at the C-3 carbon to an oxo group, and ERG27 is responsible for the reduction of the keto group on the C-3. ERG28 has a role as a scaffold to help anchor ERG25, ERG26 and ERG27 to the endoplasmic reticulum and ERG29 regulates the activity of the iron-containing C4-methylsterol oxidase ERG25. Then, the sterol 24-C-methyltransferase ERG6 catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. The C-8 sterol isomerase ERG2 catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols and thus converts fecosterol to episterol. The sterol-C5-desaturase ERG3 then catalyzes the introduction of a C-5 double bond in the B ring to produce 5-dehydroepisterol. The C-22 sterol desaturase ERG5 further converts 5-dehydroepisterol into ergosta-5,7,22,24(28)-tetraen-3beta-ol by forming the C-22(23) double bond in the sterol side chain. Finally, ergosta-5,7,22,24(28)-tetraen-3beta-ol is substrate of the C-24(28) sterol reductase ERG4 to produce ergosterol (PubMed:32679672)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUD7", "ec_number_list": [ { "id": "1.1.1.170", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.170", "type": "external" } ], "go_molecular_function": "GO:0000252 3-beta-hydroxysteroid dehydrogenase [NAD(P)+]/C4-decarboxylase activity;GO:0102175 3-beta-hydroxysteroid dehydrogenase (NAD+)/C4-decarboxylase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006696 ergosterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P53199-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53220-1", "uniprot_id": [ { "id": "TIM21_YEAST", "url": "https://www.uniprot.org/uniprot/P53220", "type": "external" } ], "mass": 27206.0, "length": 239, "protein_name": "Mitochondrial import inner membrane translocase subunit TIM21", "gene_name": "TIM21", "organism": "Yeast", "refseq_name": "Tim21p", "refseq_ac": [ { "id": "NP_011547", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011547", "type": "external" } ], "gene_names_uniprotkb": "TIM21", "gene_names_refseq": "TIM21", "protein_names_uniprotkb": "Mitochondrial import inner membrane translocase subunit TIM21", "protein_names_refseq": "Tim21p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR033C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;15797382;15878866;24374639;9169869;9290212", "class_list": "", "function": "Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to keep the TOM and the TIM23 complexes in close contact. At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix. In the complex, it acts as an antagonist of TIM50 by reducing preprotein accumulation at the TOM23 complex and promotes dissociation of the PAM complex from the TIM23 complex., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUG9;Q45U51", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005744 TIM23 mitochondrial import inner membrane translocase complex", "go_biological_process": "GO:0045039 protein insertion into mitochondrial inner membrane;GO:0030150 protein import into mitochondrial matrix", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P53220-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53253-1", "uniprot_id": [ { "id": "NNF2_YEAST", "url": "https://www.uniprot.org/uniprot/P53253", "type": "external" } ], "mass": 106466.0, "length": 936, "protein_name": "Protein NNF2", "gene_name": "NNF2", "organism": "Yeast", "refseq_name": "Nnf2p", "refseq_ac": [ { "id": "NP_011603", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011603", "type": "external" } ], "gene_names_uniprotkb": "NNF2", "gene_names_refseq": "NNF2", "protein_names_uniprotkb": "Protein NNF2", "protein_names_refseq": "Nnf2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR089W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "12872131;14562095;14562106;16847258;19779198;21126336;23749301;24374639;32597660;33491328;9169869", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUM1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P53253-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53267-1", "uniprot_id": [ { "id": "DAM1_YEAST", "url": "https://www.uniprot.org/uniprot/P53267", "type": "external" } ], "mass": 38422.0, "length": 343, "protein_name": "DASH complex subunit DAM1", "gene_name": "DAM1", "organism": "Yeast", "refseq_name": "Dam1p", "refseq_ac": [ { "id": "NP_011628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011628", "type": "external" } ], "gene_names_uniprotkb": "DAM1; G6153", "gene_names_refseq": "DAM1", "protein_names_uniprotkb": "DASH complex subunit DAM1; DUO1 and MPS1-interacting protein 1; Kinetochore assembly protein DAM1; Outer kinetochore protein DAM1", "protein_names_refseq": "Dam1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR113W)", "pathway_count": 1, "publication_count": 48, "publication_id_list": "10397771;11149931;11698664;11724818;11782438;12408861;12925767;15640796;15664196;15665377;16415853;16715078;16777964;16890524;17287358;17330950;17460120;17563356;17620411;17643123;18079178;18407956;19684113;19779198;19923271;20479468;20702584;21126336;21177495;21256019;22031224;22814378;23749301;24374639;24909858;24930965;25236177;29237818;32597660;32946748;33481703;33491328;36651597;36701236;36883282;8905931;9169869;9817759", "class_list": "", "function": "Component of the DASH complex that connects microtubules with kinetochores and couples microtubule depolymerization to chromosome movement; it is involved in retrieving kinetochores to the spindle poles before their re-orientation on the spindle in early mitosis and allows microtubule depolymerization to pull chromosomes apart and resist detachment during anaphase (PubMed:11698664, PubMed:11724818, PubMed:15664196, PubMed:16415853, PubMed:16777964, PubMed:17460120, PubMed:17643123, PubMed:9817759). Kinetochores, consisting of a centromere-associated inner segment and a microtubule-contacting outer segment, play a crucial role in chromosome segregation by mediating the physical connection between centromeric DNA and microtubules (PubMed:15664196, PubMed:17620411, PubMed:25236177). Kinetochores also serve as an input point for the spindle assembly checkpoint, which delays anaphase until all chromosomes have bioriented on the mitotic spindle (PubMed:11698664). During spindle-kinetochore attachment, kinetochores first attach to the lateral surface of spindle microtubules, which supports the congression of chromosomes toward the middle of the dividing cell; they then slide along towards the spindle pole, a process independent of the DASH complex but requiring the NDC80 complex (PubMed:17620411, PubMed:25236177). When the end of a disassembling microtubule reaches the laterally attached kinetochore, the DASH complex together with the NDC80 complex and STU2 convert lateral attachment to end-on capture to produce a structure that can track with microtubule shortening and sustain attachment when tension is applied across sister kinetochores upon their biorientation (PubMed:15640796, PubMed:15664196, PubMed:17620411, PubMed:25236177). Microtubule depolymerization proceeds by protofilament splaying and induces the kinetochore-attached DASH complex to slide longitudinally, thereby helping to transduce depolymerization energy into pulling forces to disjoin chromatids (PubMed:16415853, PubMed:16777964, PubMed:17620411). Incorrect microtubule attachments are corrected by releasing microubules from the kinetochore through phosphorylation by IPL1 of kinetochore components (PubMed:11724818, PubMed:12408861). Links the microtubule cytoskeleton to chromosomes during interphase (PubMed:36701236). Also contributes to the poleward transport of kinetochores on microtubules following centromeric DNA replication in S-phase (PubMed:18079178)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 26, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUP6;Q9P422", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0072686 mitotic spindle;GO:1990537 mitotic spindle polar microtubule;GO:0042729 DASH complex;GO:0044732 mitotic spindle pole body", "go_biological_process": "GO:0071459 protein localization to chromosome, centromeric region;GO:0008608 attachment of spindle microtubules to kinetochore;GO:0051301 cell division;GO:0031116 positive regulation of microtubule polymerization;GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore", "synthesized_glycan_count": 0, "hit_score": 4.9, "record_id": "P53267-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53277-1", "uniprot_id": [ { "id": "SYF2_YEAST", "url": "https://www.uniprot.org/uniprot/P53277", "type": "external" } ], "mass": 24803.0, "length": 215, "protein_name": "Pre-mRNA-splicing factor SYF2", "gene_name": "SYF2", "organism": "Yeast", "refseq_name": "Syf2p", "refseq_ac": [ { "id": "NP_011645", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011645", "type": "external" } ], "gene_names_uniprotkb": "SYF2; NTC31", "gene_names_refseq": "NTC31; SYF2", "protein_names_uniprotkb": "Pre-mRNA-splicing factor SYF2; PRP19 complex protein 31; Synthetic lethal with CDC40 protein 2", "protein_names_refseq": "Syf2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR129W)", "pathway_count": 1, "publication_count": 25, "publication_id_list": "11102353;11105756;11842115;11884590;12384582;14562095;14562106;14690591;17322287;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;21177495;23749301;24374639;30516470;32597660;33481703;33491328;9169869", "class_list": "", "function": "Involved in pre-mRNA splicing and cell cycle control. As a component of the NTC complex (or PRP19-associated complex), associates to the spliceosome to mediate conformational rearrangement or to stabilize the structure of the spliceosome after U4 snRNA dissociation, which leads to spliceosome maturation. The cell cycle arrest of SYF2 defective cells may be due to the inefficient splicing of TUB1., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUR1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0071006 U2-type catalytic step 1 spliceosome;GO:0071007 U2-type catalytic step 2 spliceosome;GO:0071008 U2-type post-mRNA release spliceosomal complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "P53277-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53317-1", "uniprot_id": [ { "id": "NOP19_YEAST", "url": "https://www.uniprot.org/uniprot/P53317", "type": "external" } ], "mass": 22320.0, "length": 196, "protein_name": "Nucleolar protein 19", "gene_name": "NOP19", "organism": "Yeast", "refseq_name": "Nop19p", "refseq_ac": [ { "id": "NP_011767", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011767", "type": "external" } ], "gene_names_uniprotkb": "NOP19", "gene_names_refseq": "NOP19", "protein_names_uniprotkb": "Nucleolar protein 19", "protein_names_refseq": "Nop19p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR251W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "12837249;14562095;14562106;18407956;19684113;19779198;20702584;21126336;21941128;23749301;24374639;30516470;32597660;33491328;9133742;9169869", "class_list": "", "function": "Ribosome biogenesis factor required for cleavage of pre-rRNA at A0, A1 and A2 sites. Essential for the incorporation of UTP25 in pre-ribosomes., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV31", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0030686 90S preribosome", "go_biological_process": "GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P53317-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53330-1", "uniprot_id": [ { "id": "RT102_YEAST", "url": "https://www.uniprot.org/uniprot/P53330", "type": "external" } ], "mass": 17795.0, "length": 157, "protein_name": "Regulator of Ty1 transposition protein 102", "gene_name": "RTT102", "organism": "Yeast", "refseq_name": "Rtt102p", "refseq_ac": [ { "id": "NP_011791", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011791", "type": "external" } ], "gene_names_uniprotkb": "RTT102; G9378", "gene_names_refseq": "RTT102", "protein_names_uniprotkb": "Regulator of Ty1 transposition protein 102", "protein_names_refseq": "Rtt102p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR275W)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "11779788;12748633;12775844;14562095;14562106;14660704;14729968;14759368;15506919;17322287;17330950;19779198;19795423;19823750;21126336;23749301;24374639;33229814;33481703;33491328;9133740;9169869", "class_list": "", "function": "Probable component of the chromatin structure-remodeling complex (RSC) which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton. Probable component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VV52", "ec_number_list": [], "go_molecular_function": "GO:0015616 DNA translocase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016514 SWI/SNF complex;GO:0000785 chromatin;GO:0016586 RSC-type complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007059 chromosome segregation;GO:0006368 transcription elongation by RNA polymerase II;GO:0006337 nucleosome disassembly", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "P53330-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53332-1", "uniprot_id": [ { "id": "COAD_YEAST", "url": "https://www.uniprot.org/uniprot/P53332", "type": "external" } ], "mass": 34307.0, "length": 305, "protein_name": "Phosphopantetheine adenylyltransferase", "gene_name": "CAB4", "organism": "Yeast", "refseq_name": "putative pantetheine-phosphate adenylyltransferase", "refseq_ac": [ { "id": "NP_011793", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011793", "type": "external" } ], "gene_names_uniprotkb": "CAB4", "gene_names_refseq": "CAB4", "protein_names_uniprotkb": "Phosphopantetheine adenylyltransferase; 2.7.7.3; Coenzyme A biosynthesis protein 4; Dephospho-CoA pyrophosphorylase; PPAT; Pantetheine-phosphate adenylyltransferase", "protein_names_refseq": "putative pantetheine-phosphate adenylyltransferase", "tax_id": 559292, "disease": "neurodegeneration with brain iron accumulation 6 (Disease Ontology:DOID:0110740); pontocerebellar hypoplasia type 12 (Disease Ontology:DOID:0112327); mucopolysaccharidosis III (Disease Ontology:DOID:12801); cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YGR277C); (R-SCE-196783)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "14562106;14690591;17322287;19266201;23749301;24374639;32597660;33481703;33491328;9090054;9133740;9169869", "class_list": "", "function": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity). Plays a role in the physiological regulation of the intracellular CoA concentration., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV54", "ec_number_list": [ { "id": "2.7.7.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.3", "type": "external" } ], "go_molecular_function": "GO:0004140 dephospho-CoA kinase activity;GO:0004595 pantetheine-phosphate adenylyltransferase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:1990143 CoA-synthesizing protein complex", "go_biological_process": "GO:0015937 coenzyme A biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P53332-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53549-1", "uniprot_id": [ { "id": "PRS10_YEAST", "url": "https://www.uniprot.org/uniprot/P53549", "type": "external" } ], "mass": 49408.0, "length": 437, "protein_name": "26S proteasome subunit RPT4", "gene_name": "RPT4", "organism": "Yeast", "refseq_name": "proteasome regulatory particle base subunit RPT4", "refseq_ac": [ { "id": "NP_014902", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014902", "type": "external" } ], "gene_names_uniprotkb": "RPT4; CRL13; PCS1; SUG2", "gene_names_refseq": "CRL13; PCS1; RPT4; SUG2", "protein_names_uniprotkb": "26S proteasome subunit RPT4; 26S protease subunit SUG2; Proteasomal cap subunit", "protein_names_refseq": "proteasome regulatory particle base subunit RPT4", "tax_id": 559292, "disease": "fetal alcohol spectrum disorder (Disease Ontology:DOID:0050696)", "pathway": " (sce:YOR259C); (R-SCE-1236978); (R-SCE-5668541); (R-SCE-5689880); (R-SCE-9907900)", "pathway_count": 5, "publication_count": 15, "publication_id_list": "12504901;17563356;18407956;19795423;19823750;20486117;22927375;24374639;32597660;33481703;33491328;8955118;9151663;9153759;9169874", "class_list": "", "function": "The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2W0;Q08718", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0019904 protein domain specific binding;GO:0016887 ATP hydrolysis activity;GO:0031625 ubiquitin protein ligase binding;GO:0036402 proteasome-activating activity", "go_cellular_component": "GO:0008540 proteasome regulatory particle, base subcomplex;GO:0005634 nucleus", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0036503 ERAD pathway;GO:0070682 proteasome regulatory particle assembly;GO:0006289 nucleotide-excision repair;GO:0032968 positive regulation of transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P53549-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53604-1", "uniprot_id": [ { "id": "MSO1_YEAST", "url": "https://www.uniprot.org/uniprot/P53604", "type": "external" } ], "mass": 23351.0, "length": 210, "protein_name": "Protein MSO1", "gene_name": "MSO1", "organism": "Yeast", "refseq_name": "Mso1p", "refseq_ac": [ { "id": "NP_014447", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014447", "type": "external" } ], "gene_names_uniprotkb": "MSO1; N3457", "gene_names_refseq": "MSO1", "protein_names_uniprotkb": "Protein MSO1", "protein_names_refseq": "Mso1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR049C)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "14562106;17322287;17330950;19684113;19779198;21177495;22814378;23749301;24374639;30516470;32597660;33229814;33481703;33491328;9169873;9207091", "class_list": "", "function": "Involved in secretion. Component of the secretory vesicle docking complex., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 12, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 12, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 12, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 12, "binding_glycan_count": 0, "secondary_ac_list": "D6W1M4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0031201 SNARE complex", "go_biological_process": "GO:0015031 protein transport;GO:0061025 membrane fusion;GO:0006904 vesicle docking involved in exocytosis;GO:0032120 ascospore-type prospore membrane formation", "synthesized_glycan_count": 0, "hit_score": 3.0, "record_id": "P53604-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53722-1", "uniprot_id": [ { "id": "ATP23_YEAST", "url": "https://www.uniprot.org/uniprot/P53722", "type": "external" } ], "mass": 26890.0, "length": 227, "protein_name": "Mitochondrial inner membrane protease ATP23", "gene_name": "ATP23", "organism": "Yeast", "refseq_name": "putative metalloprotease", "refseq_ac": [ { "id": "NP_014417", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014417", "type": "external" } ], "gene_names_uniprotkb": "ATP23; N3212", "gene_names_refseq": "ATP23", "protein_names_uniprotkb": "Mitochondrial inner membrane protease ATP23; 3.4.24.-", "protein_names_refseq": "putative metalloprotease", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR020C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "17135288;17135290;24374639;9169873", "class_list": "", "function": "Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes the N-terminal 10 residues of mitochondrial ATPase CF(0) subunit 6 (ATP6) at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of ATP6 with the subunit 9 ring., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1J5;Q6TQT3;Q6TQT4", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0034982 mitochondrial protein processing;GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P53722-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53731-1", "uniprot_id": [ { "id": "ARPC2_YEAST", "url": "https://www.uniprot.org/uniprot/P53731", "type": "external" } ], "mass": 39566.0, "length": 342, "protein_name": "Actin-related protein 2/3 complex subunit 2", "gene_name": "ARC35", "organism": "Yeast", "refseq_name": "Arc35p", "refseq_ac": [ { "id": "NP_014433", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014433", "type": "external" } ], "gene_names_uniprotkb": "ARC35; N3296", "gene_names_refseq": "ARC35; END9", "protein_names_uniprotkb": "Actin-related protein 2/3 complex subunit 2; Arp2/3 complex 34 kDa subunit; p34-ARC", "protein_names_refseq": "Arc35p", "tax_id": 559292, "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861); silicosis (Disease Ontology:DOID:10325); melanoma (Disease Ontology:DOID:1909); invasive ductal carcinoma (Disease Ontology:DOID:3008); systemic scleroderma (Disease Ontology:DOID:418)", "pathway": " (sce:YNR035C); (R-SCE-2029482); (R-SCE-5663213)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "14562106;17563356;18407956;21126336;23749301;24374639;32597660;33481703;33491328;9169873;9210376", "class_list": "", "function": "Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1L1", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0005200 structural constituent of cytoskeleton;GO:0005516 calmodulin binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005829 cytosol;GO:0015629 actin cytoskeleton;GO:0005885 Arp2/3 protein complex;GO:0030479 actin cortical patch", "go_biological_process": "GO:0072697 protein localization to cell cortex;GO:0030036 actin cytoskeleton organization;GO:0006898 receptor-mediated endocytosis;GO:0030041 actin filament polymerization;GO:0000226 microtubule cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P53731-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53734-1", "uniprot_id": [ { "id": "DBP6_YEAST", "url": "https://www.uniprot.org/uniprot/P53734", "type": "external" } ], "mass": 70362.0, "length": 629, "protein_name": "ATP-dependent RNA helicase DBP6", "gene_name": "DBP6", "organism": "Yeast", "refseq_name": "putative ATP-dependent RNA helicase DBP6", "refseq_ac": [ { "id": "NP_014436", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014436", "type": "external" } ], "gene_names_uniprotkb": "DBP6; N3302", "gene_names_refseq": "DBP6", "protein_names_uniprotkb": "ATP-dependent RNA helicase DBP6; 3.6.4.13; DEAD box protein 6", "protein_names_refseq": "putative ATP-dependent RNA helicase DBP6", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR038W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10567587;11565753;14562095;14562106;15126390;17145778;17330950;17563356;19779198;23749301;24374639;30516470;32597660;33481703;33491328;9169873;9528757", "class_list": "", "function": "ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1L4", "ec_number_list": [ { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "5.6.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.4", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor", "go_biological_process": "GO:0042273 ribosomal large subunit biogenesis;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P53734-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53847-1", "uniprot_id": [ { "id": "DSL1_YEAST", "url": "https://www.uniprot.org/uniprot/P53847", "type": "external" } ], "mass": 88072.0, "length": 754, "protein_name": "Protein transport protein DSL1", "gene_name": "DSL1", "organism": "Yeast", "refseq_name": "Dsl1p", "refseq_ac": [ { "id": "NP_014141", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014141", "type": "external" } ], "gene_names_uniprotkb": "DSL1; N0842", "gene_names_refseq": "DSL1; RNS1", "protein_names_uniprotkb": "Protein transport protein DSL1; Dependent on SLY1-20 protein 1", "protein_names_refseq": "Dsl1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL258C); (R-SCE-6811434)", "pathway_count": 2, "publication_count": 17, "publication_id_list": "11260526;11493604;11739780;14504276;14562106;18407956;19779198;19795423;19823750;22814378;23749301;24374639;32597660;33481703;33491328;9169873;9234673", "class_list": "", "function": "Required for protein transport between the Golgi and the endoplasmic reticulum. May tether coatomer-coated retrograde transport vesicles to the ER membrane through interaction with coatomer as well as the SNARE complex. May contribute to the stabilization of the SNARE complex., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0T5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:1990423 RZZ complex;GO:0070939 Dsl1/NZR complex;GO:0005634 nucleus;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol", "go_biological_process": "GO:0015031 protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007094 mitotic spindle assembly checkpoint signaling;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0032581 ER-dependent peroxisome organization", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P53847-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53865-1", "uniprot_id": [ { "id": "CNM67_YEAST", "url": "https://www.uniprot.org/uniprot/P53865", "type": "external" } ], "mass": 67400.0, "length": 581, "protein_name": "Chaotic nuclear migration protein 67", "gene_name": "CNM67", "organism": "Yeast", "refseq_name": "Cnm67p", "refseq_ac": [ { "id": "NP_014174", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014174", "type": "external" } ], "gene_names_uniprotkb": "CNM67; N1264", "gene_names_refseq": "CNM67", "protein_names_uniprotkb": "Chaotic nuclear migration protein 67", "protein_names_refseq": "Cnm67p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL225C)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "10899120;11514632;11742972;11973299;12796288;14515169;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;22218487;23749301;24374639;30516470;32597660;33481703;33491328;8896273;9169873;9571234", "class_list": "", "function": "Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation. Required for the proper formation of the spindle pole body (SPB) outer plaque. May connect the outer plaque to the central plaque embedded in the nuclear envelope., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 23, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0W5", "ec_number_list": [], "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton", "go_cellular_component": "GO:0005816 spindle pole body;GO:0061499 outer plaque of mitotic spindle pole body;GO:0005823 central plaque of spindle pole body;GO:0005824 outer plaque of spindle pole body", "go_biological_process": "GO:0010968 regulation of microtubule nucleation;GO:0051301 cell division;GO:0007052 mitotic spindle organization;GO:0051321 meiotic cell cycle;GO:0051300 spindle pole body organization", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P53865-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53871-1", "uniprot_id": [ { "id": "DUG3_YEAST", "url": "https://www.uniprot.org/uniprot/P53871", "type": "external" } ], "mass": 40181.0, "length": 357, "protein_name": "Probable glutamine amidotransferase DUG3", "gene_name": "DUG3", "organism": "Yeast", "refseq_name": "glutamine amidotransferase subunit DUG3", "refseq_ac": [ { "id": "NP_014208", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014208", "type": "external" } ], "gene_names_uniprotkb": "DUG3; N1410", "gene_names_refseq": "DUG3", "protein_names_uniprotkb": "Probable glutamine amidotransferase DUG3; Deficient in utilization of glutathione protein 3; GSH degradosomal complex subunit DUG3", "protein_names_refseq": "glutamine amidotransferase subunit DUG3", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL191W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;14562106;17179087;17322287;24374639;9169873", "class_list": "", "function": "Component of the GSH degradosomal complex involved in the degradation of glutathione (GSH) and other peptides containing a gamma-glu-X bond., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W0Z6", "ec_number_list": [], "go_molecular_function": "GO:0008242 omega peptidase activity;GO:0008233 peptidase activity;GO:0004044 amidophosphoribosyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0061672 glutathione hydrolase complex", "go_biological_process": "GO:0006751 glutathione catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P53871-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53879-1", "uniprot_id": [ { "id": "RHO5_YEAST", "url": "https://www.uniprot.org/uniprot/P53879", "type": "external" } ], "mass": 36818.0, "length": 331, "protein_name": "GTP-binding protein RHO5", "gene_name": "RHO5", "organism": "Yeast", "refseq_name": "Rho family GTPase RHO5", "refseq_ac": [ { "id": "NP_014219", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014219", "type": "external" } ], "gene_names_uniprotkb": "RHO5; N1644", "gene_names_refseq": "RHO5; YNS0", "protein_names_uniprotkb": "GTP-binding protein RHO5; 3.6.5.2", "protein_names_refseq": "Rho family GTPase RHO5", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL180C); (R-SCE-193648); (R-SCE-2029482); (R-SCE-389359); (R-SCE-3928662); (R-SCE-445144); (R-SCE-5625740); (R-SCE-5626467); (R-SCE-5627123); (R-SCE-5687128); (R-SCE-6798695); (R-SCE-9013149); (R-SCE-9013423); (R-SCE-983231)", "pathway_count": 14, "publication_count": 25, "publication_id_list": "11591390;12118069;14562106;17330950;17563356;18407956;18621925;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22106047;22218487;23749301;24374639;25598154;27821475;32597660;33481703;33491328;34965436;9169873", "class_list": "", "function": "Small GTPase that negatively regulates a MAP kinase branch, downstream of SLT2, of the PKC1-mediated signal transduction pathway (PubMed:12118069). With its specific guanine nucleotide exchange factor (GEF), the heterodimeric complex DCK1/LMO1, relocates to mitochondria upon oxidative stress and triggers cell death (PubMed:25598154). The DCK1/LMO1/RHO5 signaling module that mediates mitochondrial turnover under nitrogen starvation conditions via mitophagy (PubMed:25598154). The DCK1/LMO1/RHO5 signaling module also plays a role in cell wall integrity signaling (PubMed:25598154)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 20, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W106", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.4.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "1.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.3", "type": "external" }, { "id": "1.2.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.64", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005856 cytoskeleton;GO:0005886 plasma membrane", "go_biological_process": "GO:0007015 actin filament organization;GO:0007165 signal transduction;GO:0032956 regulation of actin cytoskeleton organization;GO:0006915 apoptotic process;GO:0007264 small GTPase-mediated signal transduction", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "P53879-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53883-1", "uniprot_id": [ { "id": "NOP13_YEAST", "url": "https://www.uniprot.org/uniprot/P53883", "type": "external" } ], "mass": 45609.0, "length": 403, "protein_name": "Nucleolar protein 13", "gene_name": "NOP13", "organism": "Yeast", "refseq_name": "Nop13p", "refseq_ac": [ { "id": "NP_014224", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014224", "type": "external" } ], "gene_names_uniprotkb": "NOP13; N1665", "gene_names_refseq": "NOP13", "protein_names_uniprotkb": "Nucleolar protein 13", "protein_names_refseq": "Nop13p", "tax_id": 559292, "disease": "inclusion body myopathy with Paget disease of bone and frontotemporal dementia (Disease Ontology:DOID:0050881); amyotrophic lateral sclerosis type 20 (Disease Ontology:DOID:0060211); autosomal dominant limb-girdle muscular dystrophy type 3 (Disease Ontology:DOID:0110306); distal myopathy 3 (Disease Ontology:DOID:0111189); inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 2 (Disease Ontology:DOID:0111384); inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 3 (Disease Ontology:DOID:0111386); silicosis (Disease Ontology:DOID:10325); Alzheimer's disease (Disease Ontology:DOID:10652); transient cerebral ischemia (Disease Ontology:DOID:224); HTLV-1-associated myelopathy/tropical spastic paraparesis (Disease Ontology:DOID:321); gastric adenocarcinoma (Disease Ontology:DOID:3717); lung non-small cell carcinoma (Disease Ontology:DOID:3908); uremia (Disease Ontology:DOID:4676); pancreatic carcinoma (Disease Ontology:DOID:4905); hepatocellular carcinoma (Disease Ontology:DOID:684); rheumatoid arthritis (Disease Ontology:DOID:7148)", "pathway": " (sce:YNL175C); (R-SCE-156827); (R-SCE-166208); (R-SCE-429947); (R-SCE-72649); (R-SCE-72662); (R-SCE-72702)", "pathway_count": 7, "publication_count": 18, "publication_id_list": "11452019;14562095;14562106;15665377;17330950;18407956;19779198;19795423;19823750;20702584;21126336;23749301;24374639;30516470;32597660;33481703;33491328;9169873", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 19, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 16, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W110", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0030684 preribosome;GO:0005634 nucleus;GO:0005730 nucleolus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P53883-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53919-1", "uniprot_id": [ { "id": "NAF1_YEAST", "url": "https://www.uniprot.org/uniprot/P53919", "type": "external" } ], "mass": 54949.0, "length": 492, "protein_name": "H/ACA ribonucleoprotein complex non-core subunit NAF1", "gene_name": "NAF1", "organism": "Yeast", "refseq_name": "RNA-binding snoRNP assembly protein", "refseq_ac": [ { "id": "NP_014275", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014275", "type": "external" } ], "gene_names_uniprotkb": "NAF1; N1888", "gene_names_refseq": "NAF1", "protein_names_uniprotkb": "H/ACA ribonucleoprotein complex non-core subunit NAF1; Nuclear assembly factor 1", "protein_names_refseq": "RNA-binding snoRNP assembly protein", "tax_id": 559292, "disease": "melanoma (Disease Ontology:DOID:1909)", "pathway": " (sce:YNL124W)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "12228251;12242285;12515383;14562095;14562106;14690591;15798213;15964797;17330950;17563356;17612558;18407956;18780730;19779198;19795423;19823750;24374639;33481703;33491328;8619318;9090055;9169873", "class_list": "", "function": "RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by GAR1 to yield mature H/ACA snoRNPs complex. Acts as a competitive binder for CBF5 probably required to prevent non-cognate RNAs from being loaded during transport of the particle by inducing a non-productive conformation of CBF5., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B0KZR2;B0KZS1;B0KZT9;B0KZZ3;B0L002;D6W159", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005732 sno(s)RNA-containing ribonucleoprotein complex", "go_biological_process": "GO:0042254 ribosome biogenesis;GO:0006364 rRNA processing;GO:0001522 pseudouridine synthesis;GO:0000493 box H/ACA snoRNP assembly", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P53919-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53930-1", "uniprot_id": [ { "id": "AF9_YEAST", "url": "https://www.uniprot.org/uniprot/P53930", "type": "external" } ], "mass": 25981.0, "length": 226, "protein_name": "Protein AF-9 homolog", "gene_name": "YAF9", "organism": "Yeast", "refseq_name": "YEATS domain-containing protein YAF9", "refseq_ac": [ { "id": "NP_014292", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014292", "type": "external" } ], "gene_names_uniprotkb": "YAF9; N1966", "gene_names_refseq": "YAF9", "protein_names_uniprotkb": "Protein AF-9 homolog", "protein_names_refseq": "YEATS domain-containing protein YAF9", "tax_id": 559292, "disease": "high grade glioma (Disease Ontology:DOID:3070)", "pathway": " (sce:YNL107W)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "12917332;14562095;14562106;14645854;14690591;14690608;15045029;15302830;15353583;15485911;17322287;24374639;33491328;9090055;9169873", "class_list": "", "function": "Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W173;Q6B1N1", "ec_number_list": [], "go_molecular_function": "GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0035267 NuA4 histone acetyltransferase complex;GO:0000785 chromatin;GO:0000812 Swr1 complex", "go_biological_process": "GO:0031509 subtelomeric heterochromatin formation;GO:0006281 DNA repair;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P53930-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53941-1", "uniprot_id": [ { "id": "IMP4_YEAST", "url": "https://www.uniprot.org/uniprot/P53941", "type": "external" } ], "mass": 33482.0, "length": 290, "protein_name": "U3 small nucleolar ribonucleoprotein protein IMP4", "gene_name": "IMP4", "organism": "Yeast", "refseq_name": "snoRNA-binding rRNA-processing protein IMP4", "refseq_ac": [ { "id": "NP_014324", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014324", "type": "external" } ], "gene_names_uniprotkb": "IMP4; N2353", "gene_names_refseq": "IMP4", "protein_names_uniprotkb": "U3 small nucleolar ribonucleoprotein protein IMP4; Interacting with MPP10 protein 4; U3 snoRNP protein IMP4", "protein_names_refseq": "snoRNA-binding rRNA-processing protein IMP4", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL075W); (R-SCE-6791226)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10409734;12068309;15489263;24374639;8701611;9169873", "class_list": "", "function": "Required for the early cleavages at sites A0, A1 and A2 during 18S ribosomal pre-RNA processing., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1A4", "ec_number_list": [], "go_molecular_function": "GO:0030515 snoRNA binding;GO:0043047 single-stranded telomeric DNA binding;GO:0042134 rRNA primary transcript binding;GO:0140691 RNA folding chaperone", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0030686 90S preribosome;GO:0034457 Mpp10 complex;GO:0032040 small-subunit processome", "go_biological_process": "GO:0006364 rRNA processing;GO:0042274 ribosomal small subunit biogenesis;GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P53941-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53944-1", "uniprot_id": [ { "id": "MTQ1_YEAST", "url": "https://www.uniprot.org/uniprot/P53944", "type": "external" } ], "mass": 35871.0, "length": 314, "protein_name": "Mitochondrial MRF1 N(5)-glutamine methyltransferase MTQ1", "gene_name": "MTQ1", "organism": "Yeast", "refseq_name": "S-adenosylmethionine-dependent methyltransferase", "refseq_ac": [ { "id": "NP_014336", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014336", "type": "external" } ], "gene_names_uniprotkb": "MTQ1; N2420; YNL2420W", "gene_names_refseq": "MTQ1", "protein_names_uniprotkb": "Mitochondrial MRF1 N(5)-glutamine methyltransferase MTQ1; 2.1.1.297", "protein_names_refseq": "S-adenosylmethionine-dependent methyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL063W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;16321977;17322287;24374639;8533472;9169873", "class_list": "", "function": "Methylates MRF1 on 'Gln-287' using S-adenosyl L-methionine as methyl donor., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1B7", "ec_number_list": [ { "id": "2.1.1.297", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.297", "type": "external" } ], "go_molecular_function": "GO:0008757 S-adenosylmethionine-dependent methyltransferase activity;GO:0036009 protein-glutamine N-methyltransferase activity;GO:0102559 peptide chain release factor N(5)-glutamine methyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006415 translational termination;GO:0032259 methylation;GO:0006451 translational readthrough", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P53944-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P54113-1", "uniprot_id": [ { "id": "PUR91_YEAST", "url": "https://www.uniprot.org/uniprot/P54113", "type": "external" } ], "mass": 65282.0, "length": 591, "protein_name": "Bifunctional purine biosynthesis protein ADE16", "gene_name": "ADE16", "organism": "Yeast", "refseq_name": "bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase ADE16", "refseq_ac": [ { "id": "NP_013128", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013128", "type": "external" } ], "gene_names_uniprotkb": "ADE16", "gene_names_refseq": "ADE16", "protein_names_uniprotkb": "Bifunctional purine biosynthesis protein ADE16; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase; AICAR transformylase; ATIC; IMP synthase; Inosinicase", "protein_names_refseq": "bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase ADE16", "tax_id": 559292, "disease": "purine-pyrimidine metabolic disorder (Disease Ontology:DOID:653)", "pathway": " (sce:YLR028C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10877846;14562106;19795423;19823750;24374639;33481703;33491328;9143321;9169871", "class_list": "", "function": "Bifunctional enzyme that catalyzes the last two steps of purine biosynthesis (PubMed:10877846, PubMed:9143321). Acts as a transformylase that incorporates a formyl group to the AMP analog AICAR (5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) to produce the intermediate formyl-AICAR (FAICAR) (PubMed:10877846, PubMed:9143321). Also catalyzes the cyclization of FAICAR to IMP (PubMed:10877846, PubMed:9143321)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY30;E9PAG6", "ec_number_list": [ { "id": "2.1.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.2.3", "type": "external" }, { "id": "3.5.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.10", "type": "external" } ], "go_molecular_function": "GO:0003937 IMP cyclohydrolase activity;GO:0004643 phosphoribosylaminoimidazolecarboxamide formyltransferase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006164 purine nucleotide biosynthetic process;GO:0006189 'de novo' IMP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P54113-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P54199-1", "uniprot_id": [ { "id": "MPS1_YEAST", "url": "https://www.uniprot.org/uniprot/P54199", "type": "external" } ], "mass": 86772.0, "length": 764, "protein_name": "Serine/threonine-protein kinase MPS1", "gene_name": "MPS1", "organism": "Yeast", "refseq_name": "serine/threonine/tyrosine protein kinase MPS1", "refseq_ac": [ { "id": "NP_010256", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010256", "type": "external" } ], "gene_names_uniprotkb": "MPS1; D2785; RPK1", "gene_names_refseq": "MPS1; PAC8; RPK1", "protein_names_uniprotkb": "Serine/threonine-protein kinase MPS1; 2.7.12.2; Monopolar spindle protein 1; Regulatory cell proliferation kinase 1", "protein_names_refseq": "serine/threonine/tyrosine protein kinase MPS1", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162); bipolar disorder (Disease Ontology:DOID:3312); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (sce:YDL028C)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "11278681;15296722;19269975;20489023;22521787;22561345;23749301;24374639;32597660;33481703;33491328;7737118;8028580;9046088;9169867", "class_list": "", "function": "Involved in mitotic spindle assembly checkpoint signaling, a process that delays anaphase until chromosomes are bioriented on the spindle, and in the repair of incorrect mitotic kinetochore-spindle microtubule attachments (By similarity). Phosphorylates SPC105 on MELT motifs; phosphorylation is required for recruitment of the BUB1-BUB3 complex to kinetochores (PubMed:22521787). Phosphorylates CNN1, which contributes to the enrichment of CNN1 on anaphase kinetochores (PubMed:22561345). Implicated in spindle pole body (SPD) duplication. Phosphorylates the SPC29 and SPC110 spindle pole body components (PubMed:11278681, PubMed:19269975)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 46, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRW4", "ec_number_list": [ { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.1.26.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.26.-", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.67", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005777 peroxisome;GO:0000776 kinetochore;GO:0005816 spindle pole body", "go_biological_process": "GO:0033316 meiotic spindle assembly checkpoint signaling;GO:0007059 chromosome segregation;GO:0007094 mitotic spindle assembly checkpoint signaling;GO:0051988 regulation of attachment of spindle microtubules to kinetochore;GO:0051225 spindle assembly", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P54199-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P54786-1", "uniprot_id": [ { "id": "ZDS2_YEAST", "url": "https://www.uniprot.org/uniprot/P54786", "type": "external" } ], "mass": 105496.0, "length": 942, "protein_name": "Protein ZDS2", "gene_name": "ZDS2", "organism": "Yeast", "refseq_name": "Zds2p", "refseq_ac": [ { "id": "NP_013598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013598", "type": "external" } ], "gene_names_uniprotkb": "ZDS2; MCS1; YM8339.10", "gene_names_refseq": "CES4; ZDS2", "protein_names_uniprotkb": "Protein ZDS2", "protein_names_refseq": "Zds2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YML109W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "11489916;12704202;14562106;16157662;17287358;17330950;17563356;19779198;19795423;19823750;20702584;21177495;23749301;24374639;32597660;33481703;33491328;8816438;9169872", "class_list": "", "function": "Acts as a negative regulator of polarized growth via an alternative mechanism to ZDS1. In heat-stressed cells appears to play a role in localizing BCY1 to the cytoplasm. Seems to interact with, and down-regulate, CDC42. Also acts as a suppressor of PKC1. May act as an integration point for distinct signaling pathways helping to maintain a balance among these different pathways., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 29, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0H5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005934 cellular bud tip;GO:0005935 cellular bud neck", "go_biological_process": "GO:0010971 positive regulation of G2/M transition of mitotic cell cycle;GO:0032880 regulation of protein localization;GO:0030010 establishment of cell polarity;GO:0000183 rDNA heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P54786-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P54790-1", "uniprot_id": [ { "id": "ORC3_YEAST", "url": "https://www.uniprot.org/uniprot/P54790", "type": "external" } ], "mass": 72077.0, "length": 616, "protein_name": "Origin recognition complex subunit 3", "gene_name": "ORC3", "organism": "Yeast", "refseq_name": "origin recognition complex subunit 3", "refseq_ac": [ { "id": "NP_013097", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013097", "type": "external" } ], "gene_names_uniprotkb": "ORC3; L1365; OAF1; OIF1", "gene_names_refseq": "ORC3", "protein_names_uniprotkb": "Origin recognition complex subunit 3; Origin recognition complex 62 kDa subunit", "protein_names_refseq": "origin recognition complex subunit 3", "tax_id": 559292, "disease": "", "pathway": " (sce:YLL004W); (R-SCE-176187); (R-SCE-68616); (R-SCE-68689); (R-SCE-68962)", "pathway_count": 5, "publication_count": 8, "publication_id_list": "18006685;22814378;24374639;33491328;7585959;8657159;8810043;9169871", "class_list": "", "function": "Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXZ9", "ec_number_list": [], "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0003682 chromatin binding", "go_cellular_component": "GO:0005656 nuclear pre-replicative complex;GO:0031261 DNA replication preinitiation complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005664 nuclear origin of replication recognition complex", "go_biological_process": "GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication;GO:0006270 DNA replication initiation;GO:0030466 silent mating-type cassette heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P54790-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P54837-1", "uniprot_id": [ { "id": "TMEDA_YEAST", "url": "https://www.uniprot.org/uniprot/P54837", "type": "external" } ], "mass": 24106.0, "length": 211, "protein_name": "Endoplasmic reticulum vesicle protein 25", "gene_name": "ERV25", "organism": "Yeast", "refseq_name": "Erv25p", "refseq_ac": [ { "id": "NP_013701", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013701", "type": "external" } ], "gene_names_uniprotkb": "ERV25; YM9571.06", "gene_names_refseq": "ERV25", "protein_names_uniprotkb": "Endoplasmic reticulum vesicle protein 25", "protein_names_refseq": "Erv25p", "tax_id": 559292, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652)", "pathway": " (sce:YML012W); (R-SCE-6807878); (R-SCE-6811434)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "10359606;10713261;11560939;14562106;16107716;24374639;8900179;9169872", "class_list": "", "function": "Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. Possesses a C-terminal dilysine motif that interacts with COPI coat subunits. Facilitates retrograde transport from the Golgi to the endoplasmic reticulum., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZG2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005798 Golgi-associated vesicle;GO:0030134 COPII-coated ER to Golgi transport vesicle", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006900 vesicle budding from membrane;GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P54837-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P80210-1", "uniprot_id": [ { "id": "PURA_YEAST", "url": "https://www.uniprot.org/uniprot/P80210", "type": "external" } ], "mass": 48279.0, "length": 433, "protein_name": "Adenylosuccinate synthetase", "gene_name": "ADE12", "organism": "Yeast", "refseq_name": "adenylosuccinate synthase", "refseq_ac": [ { "id": "NP_014179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014179", "type": "external" } ], "gene_names_uniprotkb": "ADE12; N1290", "gene_names_refseq": "ADE12; BRA9", "protein_names_uniprotkb": "Adenylosuccinate synthetase; 6.3.4.4; AMPSase; AS-synthetase; AdSS; IMP--aspartate ligase", "protein_names_refseq": "adenylosuccinate synthase", "tax_id": 559292, "disease": "sarcoma (Disease Ontology:DOID:1115)", "pathway": " (sce:YNL220W); (R-SCE-73817)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "10417315;14562095;14562106;18407956;21126336;24374639;33491328;7603488;8376380;8706758;9169873;9668204", "class_list": "", "function": "Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W0X0", "ec_number_list": [ { "id": "6.3.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.4", "type": "external" } ], "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0000287 magnesium ion binding;GO:0005525 GTP binding;GO:0004019 adenylosuccinate synthase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0046040 IMP metabolic process;GO:0006164 purine nucleotide biosynthetic process;GO:0044208 'de novo' AMP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P80210-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P89102-1", "uniprot_id": [ { "id": "SEC5_YEAST", "url": "https://www.uniprot.org/uniprot/P89102", "type": "external" } ], "mass": 112121.0, "length": 971, "protein_name": "Exocyst complex component SEC5", "gene_name": "SEC5", "organism": "Yeast", "refseq_name": "exocyst subunit SEC5", "refseq_ac": [ { "id": "NP_010450", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010450", "type": "external" } ], "gene_names_uniprotkb": "SEC5; YD8358.20C; YD9489.01C", "gene_names_refseq": "SEC5", "protein_names_uniprotkb": "Exocyst complex component SEC5", "protein_names_refseq": "exocyst subunit SEC5", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR166C); (R-SCE-264876)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "14562106;17330950;18407956;19779198;23749301;24374639;33481703;33491328;8978675;9169867", "class_list": "", "function": "Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSE6;Q03775;Q04128", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0071944 cell periphery;GO:0000145 exocyst;GO:0000131 incipient cellular bud site;GO:0005628 prospore membrane;GO:0005934 cellular bud tip", "go_biological_process": "GO:0015031 protein transport;GO:0006887 exocytosis;GO:0006893 Golgi to plasma membrane transport;GO:0006904 vesicle docking involved in exocytosis;GO:0001927 exocyst assembly", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P89102-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q00764-1", "uniprot_id": [ { "id": "TPS1_YEAST", "url": "https://www.uniprot.org/uniprot/Q00764", "type": "external" } ], "mass": 56148.0, "length": 495, "protein_name": "Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit", "gene_name": "TPS1", "organism": "Yeast", "refseq_name": "alpha,alpha-trehalose-phosphate synthase (UDP-forming) TPS1", "refseq_ac": [ { "id": "NP_009684", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009684", "type": "external" } ], "gene_names_uniprotkb": "TPS1; BYP1; CIF1; FDP1; GGS1; GLC6; TSS1; YBR0922", "gene_names_refseq": "BYP1; CIF1; FDP1; GGS1; GLC6; TPS1; TSS1", "protein_names_uniprotkb": "Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit; 2.4.1.15; General glucose sensor subunit 1; Glycogen metabolism control protein GLC6; Trehalose synthase complex catalytic subunit TPS1; Trehalose-6-phosphate synthase; UDP-glucose-glucosephosphate glucosyltransferase", "protein_names_refseq": "alpha,alpha-trehalose-phosphate synthase (UDP-forming) TPS1", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR126C)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "11059292;1315471;1425702;14562095;14562106;17322287;18407956;22814378;24374639;2521486;2546763;33481703;33491328;7813418;7900426;8091856;8150278;8355617;8404904;8404905;8467996;9194697;9837904", "class_list": "glycogene;glycosyltransferase", "function": "Synthase catalytic subunit of the trehalose synthase complex that catalyzes the production of trehalose from glucose-6-phosphate and UDP-alpha-D-glucose in a two step process. Can function independently of the complex., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQC3;Q01801;Q05168;Q6J5J4", "ec_number_list": [ { "id": "2.4.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.15", "type": "external" } ], "go_molecular_function": "GO:0004805 trehalose-phosphatase activity;GO:0003825 alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005946 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0034605 cellular response to heat;GO:0071465 cellular response to desiccation;GO:0005992 trehalose biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "Q00764-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q00776-1", "uniprot_id": [ { "id": "AP1M1_YEAST", "url": "https://www.uniprot.org/uniprot/Q00776", "type": "external" } ], "mass": 53874.0, "length": 475, "protein_name": "AP-1 complex subunit mu-1-I", "gene_name": "APM1", "organism": "Yeast", "refseq_name": "Apm1p", "refseq_ac": [ { "id": "NP_015064", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015064", "type": "external" } ], "gene_names_uniprotkb": "APM1; P0394; YAP54", "gene_names_refseq": "APM1; YAP54", "protein_names_uniprotkb": "AP-1 complex subunit mu-1-I; Clathrin assembly protein complex 1 mu-1-I medium chain; Clathrin coat assembly protein AP54; Clathrin coat-associated protein AP54; Golgi adaptor AP-1 54 kDa protein; HA1 54 kDa subunit; Mu(1)-adaptin; Mu1-I-adaptin", "protein_names_refseq": "Apm1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL259C); (R-SCE-432720); (R-SCE-6798695)", "pathway_count": 3, "publication_count": 7, "publication_id_list": "10564262;14562106;1761056;23749301;24374639;33491328;9169875", "class_list": "", "function": "Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. The AP-1 complex interacts directly with clathrin. AP57 is probably a subunit of the Golgi membrane adaptor., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3B0", "ec_number_list": [], "go_molecular_function": "GO:0035615 clathrin adaptor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005905 clathrin-coated pit;GO:0005802 trans-Golgi network;GO:0030121 AP-1 adaptor complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0048203 vesicle targeting, trans-Golgi to endosome;GO:0006896 Golgi to vacuole transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q00776-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q00916-1", "uniprot_id": [ { "id": "RU17_YEAST", "url": "https://www.uniprot.org/uniprot/Q00916", "type": "external" } ], "mass": 34447.0, "length": 300, "protein_name": "U1 small nuclear ribonucleoprotein 70 kDa homolog", "gene_name": "SNP1", "organism": "Yeast", "refseq_name": "U1 snRNP complex subunit SNP1", "refseq_ac": [ { "id": "NP_012203", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012203", "type": "external" } ], "gene_names_uniprotkb": "SNP1", "gene_names_refseq": "SNP1", "protein_names_uniprotkb": "U1 small nuclear ribonucleoprotein 70 kDa homolog; U1 70K; U1 small nuclear ribonucleoprotein SNP1; U1 snRNP 70 kDa homolog; U1 snRNP protein SNP1; U1-70K", "protein_names_refseq": "U1 snRNP complex subunit SNP1", "tax_id": 559292, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); disease of mental health (Disease Ontology:DOID:150); mixed connective tissue disease (Disease Ontology:DOID:3492); systemic lupus erythematosus (Disease Ontology:DOID:9074)", "pathway": " (sce:YIL061C)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10072386;11425851;11804584;1387202;14562106;1714384;17322287;24374639;33481703;33491328;7565787;8643384;9012791;9169870;9630245", "class_list": "", "function": "Involved in nuclear mRNA splicing., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VVM3", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0030619 U1 snRNA binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0005634 nucleus;GO:0000243 commitment complex;GO:0071004 U2-type prespliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0000395 mRNA 5'-splice site recognition", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q00916-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q01329-1", "uniprot_id": [ { "id": "PTA1_YEAST", "url": "https://www.uniprot.org/uniprot/Q01329", "type": "external" } ], "mass": 88473.0, "length": 785, "protein_name": "Pre-tRNA-processing protein PTA1", "gene_name": "PTA1", "organism": "Yeast", "refseq_name": "RNA-processing protein PTA1", "refseq_ac": [ { "id": "NP_009356", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009356", "type": "external" } ], "gene_names_uniprotkb": "PTA1; FUN39", "gene_names_refseq": "FUN39; PTA1", "protein_names_uniprotkb": "Pre-tRNA-processing protein PTA1", "protein_names_refseq": "RNA-processing protein PTA1", "tax_id": 559292, "disease": "", "pathway": " (sce:YAL043C); (R-SCE-77595)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "12819204;14562106;1508188;18407956;19779198;21126336;21177495;23749301;24374639;30516470;33229814;33491328;7731988", "class_list": "", "function": "Essential in pre-tRNA processing. Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Component of the APT complex, which may be involved in polyadenylation-independent transcript 3'-end formation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 7, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 7, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 7, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 24, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "D6VPH3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005847 mRNA cleavage and polyadenylation specificity factor complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0008033 tRNA processing;GO:0030846 termination of RNA polymerase II transcription, poly(A)-coupled", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "Q01329-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q01389-1", "uniprot_id": [ { "id": "BCK1_YEAST", "url": "https://www.uniprot.org/uniprot/Q01389", "type": "external" } ], "mass": 164195.0, "length": 1478, "protein_name": "Serine/threonine-protein kinase BCK1/SLK1/SSP31", "gene_name": "BCK1", "organism": "Yeast", "refseq_name": "mitogen-activated protein kinase kinase kinase BCK1", "refseq_ac": [ { "id": "NP_012440", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012440", "type": "external" } ], "gene_names_uniprotkb": "BCK1; J0906; LAS3; SLK1; SSP31", "gene_names_refseq": "BCK1; LAS3; SAP3; SLK1; SSP31", "protein_names_uniprotkb": "Serine/threonine-protein kinase BCK1/SLK1/SSP31; 2.7.11.1", "protein_names_refseq": "mitogen-activated protein kinase kinase kinase BCK1", "tax_id": 559292, "disease": "immunodeficiency 112 (Disease Ontology:DOID:0061079); stomach cancer (Disease Ontology:DOID:10534); primary biliary cholangitis (Disease Ontology:DOID:12236); Sjogren's syndrome (Disease Ontology:DOID:12894); proliferative diabetic retinopathy (Disease Ontology:DOID:13207); background diabetic retinopathy (Disease Ontology:DOID:13208); lung cancer (Disease Ontology:DOID:1324); breast cancer (Disease Ontology:DOID:1612); lung non-small cell carcinoma (Disease Ontology:DOID:3908); clear cell renal cell carcinoma (Disease Ontology:DOID:4467); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (sce:YJL095W); (R-SCE-389357); (R-SCE-5607761); (R-SCE-5668541); (R-SCE-5676590)", "pathway_count": 5, "publication_count": 25, "publication_id_list": "14562106;1545797;17287358;1729597;17330950;17563356;1840547;18407956;19779198;19795423;19823750;20489023;20702584;21126336;21177495;23749301;24374639;28270554;31208443;32597660;33229814;33481703;33491328;7871887;8641269", "class_list": "", "function": "Serine/threonine protein kinase involved in a signal transduction pathway that plays a role in yeast cell morphogenesis and cell growth. This pathway seems to start by SMP3; then involve the kinase PKC1 that may act on this kinase. BCK1 probably phosphorylates MKK1 and MKK2 which themselves phosphorylate the MPK1 kinase., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 9, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 9, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 9, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 101, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 11, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "D6VW89;P32894", "ec_number_list": [ { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "3.1.26.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.26.-", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.67", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004709 MAP kinase kinase kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005935 cellular bud neck;GO:0043332 mating projection tip", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0000165 MAPK cascade;GO:0030968 endoplasmic reticulum unfolded protein response;GO:0010447 response to acidic pH;GO:0030010 establishment of cell polarity", "synthesized_glycan_count": 0, "hit_score": 3.6, "record_id": "Q01389-1", "record_type": "protein", "filter_code": "0000000.0100111.010000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q01448-1", "uniprot_id": [ { "id": "HPC2_YEAST", "url": "https://www.uniprot.org/uniprot/Q01448", "type": "external" } ], "mass": 67775.0, "length": 625, "protein_name": "Histone promoter control protein 2", "gene_name": "HPC2", "organism": "Yeast", "refseq_name": "Hpc2p", "refseq_ac": [ { "id": "NP_009774", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009774", "type": "external" } ], "gene_names_uniprotkb": "HPC2; YBR1503", "gene_names_refseq": "HPC2", "protein_names_uniprotkb": "Histone promoter control protein 2", "protein_names_refseq": "Hpc2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR215W); (R-SCE-2559584)", "pathway_count": 2, "publication_count": 28, "publication_id_list": "12524332;1406694;14562095;14562106;16264190;16303565;17244705;17287358;17330950;17563356;18407956;19683497;19779198;19795423;19823750;20190278;20702584;21177495;22218487;23749301;24374639;25344756;30516470;32597660;33481703;33491328;33502312;7813418", "class_list": "", "function": "Component of the HIR complex, which functions as a histone chaperone that cooperates with ASF1 to promote replication-independent chromatin assembly. The HIR complex is also required for the periodic repression of three of the four histone gene loci during cell cycle as well as for autogenous regulation of the HTA1-HTB1 locus by H2A and H2B. DNA-binding by the HIR complex may repress transcription by inhibiting nucleosome remodeling by the SWI/SNF complex. The HIR complex may also be required for transcriptional silencing of centromeric, telomeric and mating-type loci in the absence of CAF-1., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 36, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A2TBP6;D6VQL1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome;GO:0000417 HIR complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0006325 chromatin organization;GO:0000082 G1/S transition of mitotic cell cycle;GO:0006334 nucleosome assembly;GO:0006368 transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "Q01448-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02199-1", "uniprot_id": [ { "id": "NUP49_YEAST", "url": "https://www.uniprot.org/uniprot/Q02199", "type": "external" } ], "mass": 49142.0, "length": 472, "protein_name": "Nucleoporin NUP49/NSP49", "gene_name": "NUP49", "organism": "Yeast", "refseq_name": "FG-nucleoporin NUP49", "refseq_ac": [ { "id": "NP_011343", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011343", "type": "external" } ], "gene_names_uniprotkb": "NUP49; G1648; NSP49", "gene_names_refseq": "NSP49; NUP49", "protein_names_uniprotkb": "Nucleoporin NUP49/NSP49; Nuclear pore protein NUP49/NSP49", "protein_names_refseq": "FG-nucleoporin NUP49", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL172W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10684247;11387327;11689687;12604785;12791264;1385442;14562106;1464327;15039779;24374639;7813444;8524308;8619317;9017593;9169869;9971735", "class_list": "", "function": "Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm). NUP49 plays an important role in several nuclear transport pathways including poly(A)+ RNA, tRNA, and pre-ribosome transport., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VTY0", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0042802 identical protein binding;GO:0017056 structural constituent of nuclear pore;GO:0008139 nuclear localization sequence binding;GO:0140693 molecular condensate scaffold activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005643 nuclear pore;GO:0031965 nuclear membrane;GO:0044614 nuclear pore cytoplasmic filaments;GO:0044613 nuclear pore central transport channel", "go_biological_process": "GO:0016973 poly(A)+ mRNA export from nucleus;GO:0000055 ribosomal large subunit export from nucleus;GO:0006409 tRNA export from nucleus;GO:0006913 nucleocytoplasmic transport;GO:1990000 amyloid fibril formation", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q02199-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02336-1", "uniprot_id": [ { "id": "ADA2_YEAST", "url": "https://www.uniprot.org/uniprot/Q02336", "type": "external" } ], "mass": 50569.0, "length": 434, "protein_name": "SAGA complex subunit ADA2", "gene_name": "ADA2", "organism": "Yeast", "refseq_name": "chromatin-binding transcription regulator ADA2", "refseq_ac": [ { "id": "NP_010736", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010736", "type": "external" } ], "gene_names_uniprotkb": "ADA2; D9461.33", "gene_names_refseq": "ADA2; SWI8", "protein_names_uniprotkb": "SAGA complex subunit ADA2; Transcriptional adapter 2", "protein_names_refseq": "chromatin-binding transcription regulator ADA2", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR448W)", "pathway_count": 1, "publication_count": 27, "publication_id_list": "10026213;10490601;10864329;12186975;12446794;14562106;15260971;15340070;15647753;1638630;18950642;19737915;21177495;24374639;25216679;28918903;30224453;33491328;33864814;7862114;7957049;7972120;9154821;9169867;9224714;9674426;9885573", "class_list": "", "function": "Component of the transcription coactivator SAGA complex. SAGA acts as a general cofactor required for essentially all RNA polymerase II transcription (PubMed:10864329, PubMed:25216679, PubMed:28918903). At the promoters, SAGA is required for transcription pre-initiation complex (PIC) recruitment. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (via core/TAF module) and promoter selectivity, interaction with transcription activators (via Tra1/SPT module), and chromatin modification through histone acetylation (via HAT module) and deubiquitination (via DUB module) (PubMed:18950642, PubMed:7972120). SAGA preferentially acetylates histones H3 (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac) and H2B and deubiquitinates histone H2B (PubMed:10026213). SAGA interacts with DNA via upstream activating sequences (UASs) (PubMed:28918903). Also identified in a modified version of SAGA named SALSA or SLIK (PubMed:12186975, PubMed:12446794). The cleavage of SPT7 and the absence of the SPT8 subunit in SLIK neither drive any major conformational differences in its structure compared with SAGA, nor significantly affect HAT, DUB, or DNA-binding activities (PubMed:33864814). Component of the ADA histone acetyltransferase complex, which preferentially acetylates nucleosomal histones H3 (to form H3K14ac and H3K18ac) and H2B (PubMed:10026213, PubMed:9224714). Positioned at chromosomal termini to participate in both transcriptional repression and activation in response to nutrient signaling, promoting transcriptional silencing at telomeres and ribosomal DNA (PubMed:19737915). May be involved in response to DNA damage by genotoxic agents (PubMed:15340070)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT73", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0001786 phosphatidylserine binding", "go_cellular_component": "GO:0070461 SAGA-type complex;GO:0005634 nucleus;GO:0000124 SAGA complex;GO:0000781 chromosome, telomeric region;GO:0046695 SLIK (SAGA-like) complex", "go_biological_process": "GO:0031509 subtelomeric heterochromatin formation;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 2.8, "record_id": "Q02336-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02455-1", "uniprot_id": [ { "id": "MLP1_YEAST", "url": "https://www.uniprot.org/uniprot/Q02455", "type": "external" } ], "mass": 218456.0, "length": 1875, "protein_name": "Protein MLP1", "gene_name": "MLP1", "organism": "Yeast", "refseq_name": "Mlp1p", "refseq_ac": [ { "id": "NP_013021", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013021", "type": "external" } ], "gene_names_uniprotkb": "MLP1; YKR415", "gene_names_refseq": "MLP1; MPL1", "protein_names_uniprotkb": "Protein MLP1; Myosin-like protein 1", "protein_names_refseq": "Mlp1p", "tax_id": 559292, "disease": "autosomal recessive intellectual developmental disorder (Disease Ontology:DOID:0060308); lung cancer (Disease Ontology:DOID:1324)", "pathway": " (sce:YKR095W)", "pathway_count": 1, "publication_count": 29, "publication_id_list": "10085285;10638763;11862215;12490156;12531921;14562106;14574415;14718167;16027220;17563356;18407956;19779198;19795423;19823750;20190278;21126336;21177495;22218487;22814378;23749301;24152732;24374639;32597660;33229814;33481703;33491328;8154186;8196765;8483450", "class_list": "", "function": "Together with the closely related MLP2, involved in the structural and functional organization of perinuclear chromatin (PubMed:10638763). Together with MLP2, associates with the nuclear pore complex and form filamentous structures along the nuclear periphery (PubMed:10085285, PubMed:24152732). Has a role in the localization of Esc1 to nucleolar regions (PubMed:24152732). Together with MLP2, mediates tethering of the some telomeres to the nuclear periphery, probably mediated by YKU70/YKU80 (HDF1/HDF2) heterodimer and show perinuclear location dependent silencing (PubMed:11862215). MLP1 and MLP2 are involved in telomere length regulation but not silencing or telomere anchoring (PubMed:12490156). Recognizes the 5'-splice site of pre-mRNAs and retains unspliced pre-mRNA in the nucleus without affecting splicing itself (PubMed:12490156, PubMed:12531921, PubMed:14718167)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 54, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VXF5", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0043021 ribonucleoprotein complex binding;GO:0017056 structural constituent of nuclear pore;GO:0140586 promoter-terminator loop anchoring activity", "go_cellular_component": "GO:0044615 nuclear pore nuclear basket;GO:0005635 nuclear envelope;GO:0005643 nuclear pore;GO:0005654 nucleoplasm", "go_biological_process": "GO:0016973 poly(A)+ mRNA export from nucleus;GO:0071028 nuclear mRNA surveillance;GO:0006281 DNA repair;GO:0006406 mRNA export from nucleus;GO:0006913 nucleocytoplasmic transport", "synthesized_glycan_count": 0, "hit_score": 3.3, "record_id": "Q02455-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02774-1", "uniprot_id": [ { "id": "SHR3_YEAST", "url": "https://www.uniprot.org/uniprot/Q02774", "type": "external" } ], "mass": 23512.0, "length": 210, "protein_name": "Secretory component protein SHR3", "gene_name": "SHR3", "organism": "Yeast", "refseq_name": "Shr3p", "refseq_ac": [ { "id": "NP_010069", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010069", "type": "external" } ], "gene_names_uniprotkb": "SHR3; D1022", "gene_names_refseq": "APF1; SHR3", "protein_names_uniprotkb": "Secretory component protein SHR3", "protein_names_refseq": "Shr3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL212W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "1423607;14562106;16847258;17322287;24374639;9046097;9169867", "class_list": "", "function": "Involved in amino acid permease processing and required for the efficient translocation of structurally related amino acid permeases from the endoplasmic reticulum to the plasma membrane. SHR3 may function as a permease-specific 'adaptor' molecule that functions in conjunction with the SEC62/SEC63 complex. Yeast cells may require SHR3 to expedite the processing of permeases to ensure their rapid expression at the plasma membrane in response to changing environmental conditions., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRE2;Q12413", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0043332 mating projection tip", "go_biological_process": "GO:0015031 protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006457 protein folding;GO:0090114 COPII-coated vesicle budding", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q02774-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02785-1", "uniprot_id": [ { "id": "PDR12_YEAST", "url": "https://www.uniprot.org/uniprot/Q02785", "type": "external" } ], "mass": 171065.0, "length": 1511, "protein_name": "ATP-dependent permease PDR12", "gene_name": "PDR12", "organism": "Yeast", "refseq_name": "ATP-binding cassette multidrug transporter PDR12", "refseq_ac": [ { "id": "NP_015267", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015267", "type": "external" } ], "gene_names_uniprotkb": "PDR12; LPE14C", "gene_names_refseq": "PDR12", "protein_names_uniprotkb": "ATP-dependent permease PDR12", "protein_names_refseq": "ATP-binding cassette multidrug transporter PDR12", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL058C)", "pathway_count": 1, "publication_count": 31, "publication_id_list": "10419965;10931353;12588995;12734796;12869194;12872131;14562095;14562106;14617816;15665377;16847258;16911515;17141908;17330950;17509074;17563356;18407956;18621731;18800175;19684113;19779198;20702584;21177495;22814378;23749301;24374639;32597660;33481703;33491328;9169875;9687494", "class_list": "", "function": "Plasma membrane transporter which mediates resistance to water-soluble, monocarboxylic acids with chain lengths of from C1 to C7 by active extrusion of the preservative anions from the cytosol. Also involved in the export of aromatic and branched-chain organic acids produced in amino acid catabolism., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W3V6", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0022857 transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0015849 organic acid transport", "synthesized_glycan_count": 0, "hit_score": 3.2, "record_id": "Q02785-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02794-1", "uniprot_id": [ { "id": "STD1_YEAST", "url": "https://www.uniprot.org/uniprot/Q02794", "type": "external" } ], "mass": 50261.0, "length": 444, "protein_name": "Protein STD1", "gene_name": "STD1", "organism": "Yeast", "refseq_name": "Std1p", "refseq_ac": [ { "id": "NP_014690", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014690", "type": "external" } ], "gene_names_uniprotkb": "STD1; MSN3; SFS3", "gene_names_refseq": "MSN3; SFS3; STD1", "protein_names_uniprotkb": "Protein STD1; Glucose repression modulator MSN3; Suppressor of Tbp deletion protein 1; Suppressor of fluoride sensitivity 3", "protein_names_refseq": "Std1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR047C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10373505;12618390;14562106;19797769;24374639;8114728;8497275;9169874", "class_list": "", "function": "Involved in modulation of glucose-regulated gene expression. Together with MTH1, represses the hexose transporter (HXT) genes in conditions of low glucose. Stimulates the SNF1 kinase by an interaction with the catalytic domain that antagonizes autoinhibition and promotes an active conformation of the kinase., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2B3", "ec_number_list": [], "go_molecular_function": "GO:0030295 protein kinase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007165 signal transduction;GO:0006006 glucose metabolic process;GO:0009651 response to salt stress", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q02794-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02795-1", "uniprot_id": [ { "id": "OSTD_YEAST", "url": "https://www.uniprot.org/uniprot/Q02795", "type": "external" } ], "mass": 31653.0, "length": 286, "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1", "gene_name": "SWP1", "organism": "Yeast", "refseq_name": "dolichyl-diphosphooligosaccharide-protein glycotransferase", "refseq_ac": [ { "id": "NP_013869", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013869", "type": "external" } ], "gene_names_uniprotkb": "SWP1; YM9375.19", "gene_names_refseq": "SWP1", "protein_names_uniprotkb": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1; Oligosaccharyl transferase subunit SWP1; Oligosaccharyl transferase subunit delta", "protein_names_refseq": "dolichyl-diphosphooligosaccharide-protein glycotransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR149W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "11580295;14562095;14562106;15831493;15886282;16096345;16096346;16297388;17322287;24374639;29301962;29466327;7703229;8175708;8181570;8428586;9169872;9405463;9878773", "class_list": "", "function": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZX1", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0008250 oligosaccharyltransferase complex", "go_biological_process": "GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q02795-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02890-1", "uniprot_id": [ { "id": "PNG1_YEAST", "url": "https://www.uniprot.org/uniprot/Q02890", "type": "external" } ], "mass": 42485.0, "length": 363, "protein_name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "gene_name": "PNG1", "organism": "Yeast", "refseq_name": "peptide-N4-(N-acetyl-beta- glucosaminyl)asparagine amidase", "refseq_ac": [ { "id": "NP_015229", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015229", "type": "external" } ], "gene_names_uniprotkb": "PNG1", "gene_names_refseq": "PNG1", "protein_names_uniprotkb": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; 3.5.1.52; PNGase; Peptide:N-glycanase 1; yPNG1", "protein_names_refseq": "peptide-N4-(N-acetyl-beta- glucosaminyl)asparagine amidase", "tax_id": 559292, "disease": "congenital disorder of deglycosylation 1 (Disease Ontology:DOID:0060728); congenital disorder of deglycosylation (Disease Ontology:DOID:0060991)", "pathway": " (sce:YPL096W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "10831608;11259433;11812789;12606569;12723970;14562095;14562106;14726951;15351714;15610852;15670854;15964983;16003388;16401726;16740630;23749301;24374639;33491328;9169875", "class_list": "", "function": "Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins. Involved in the formation of free oligosaccharide in cytosol., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 45, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3S1", "ec_number_list": [], "go_molecular_function": "GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0036503 ERAD pathway;GO:0006517 protein deglycosylation;GO:0006515 protein quality control for misfolded or incompletely synthesized proteins;GO:0097466 ubiquitin-dependent glycoprotein ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q02890-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03213-1", "uniprot_id": [ { "id": "HOT1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03213", "type": "external" } ], "mass": 79416.0, "length": 719, "protein_name": "High-osmolarity-induced transcription protein 1", "gene_name": "HOT1", "organism": "Yeast", "refseq_name": "Hot1p", "refseq_ac": [ { "id": "NP_013895", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013895", "type": "external" } ], "gene_names_uniprotkb": "HOT1; YM8010.02", "gene_names_refseq": "HOT1", "protein_names_uniprotkb": "High-osmolarity-induced transcription protein 1", "protein_names_refseq": "Hot1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR172W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10409737;10722658;11336700;12743037;14562095;14562106;18407956;19779198;23749301;24374639;28270554;31208443;32597660;33229814;33481703;33491328;9169872", "class_list": "", "function": "Required for a complete transcriptional response to osmotic stress, through recruitment of HOG1 followed by pol II recruitment to the promoters of GPD1 and other HOG-dependent genes., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 5, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 5, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 5, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 18, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VZZ4", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0016251 RNA polymerase II general transcription initiation factor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0071470 cellular response to osmotic stress;GO:0051123 RNA polymerase II preinitiation complex assembly;GO:0060963 positive regulation of ribosomal protein gene transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "Q03213-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03214-1", "uniprot_id": [ { "id": "ECM5_YEAST", "url": "https://www.uniprot.org/uniprot/Q03214", "type": "external" } ], "mass": 162701.0, "length": 1411, "protein_name": "Protein ECM5", "gene_name": "ECM5", "organism": "Yeast", "refseq_name": "Ecm5p", "refseq_ac": [ { "id": "NP_013901", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013901", "type": "external" } ], "gene_names_uniprotkb": "ECM5; YM8010.06", "gene_names_refseq": "ECM5", "protein_names_uniprotkb": "Protein ECM5; Extracellular matrix protein 5", "protein_names_refseq": "Ecm5p", "tax_id": 559292, "disease": "prostate cancer (Disease Ontology:DOID:10283); cryptorchidism (Disease Ontology:DOID:11383); breast cancer (Disease Ontology:DOID:1612); lung non-small cell carcinoma (Disease Ontology:DOID:3908); stomach carcinoma (Disease Ontology:DOID:5517); ankylosing spondylitis (Disease Ontology:DOID:7147); alopecia areata (Disease Ontology:DOID:986)", "pathway": " (sce:YMR176W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;21126336;24374639;33491328;9169872;9335584", "class_list": "", "function": "May be involved in cell wall organization and biogenesis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZZ9", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000785 chromatin;GO:0070211 Snt2C complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006979 response to oxidative stress;GO:0006355 regulation of DNA-templated transcription;GO:0034599 cellular response to oxidative stress;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q03214-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03322-1", "uniprot_id": [ { "id": "TLG1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03322", "type": "external" } ], "mass": 25817.0, "length": 224, "protein_name": "t-SNARE affecting a late Golgi compartment protein 1", "gene_name": "TLG1", "organism": "Yeast", "refseq_name": "Tlg1p", "refseq_ac": [ { "id": "NP_010756", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010756", "type": "external" } ], "gene_names_uniprotkb": "TLG1; D8035.11", "gene_names_refseq": "TLG1", "protein_names_uniprotkb": "t-SNARE affecting a late Golgi compartment protein 1; Syntaxin TLG1", "protein_names_refseq": "Tlg1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR468C); (R-SCE-6811440)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "10397773;11237004;11689439;11739407;12006655;12377769;12686613;14675424;15973437;17322287;22106047;24374639;9169867;9427746", "class_list": "", "function": "SNARE protein (of Qc type) involved in membrane fusion probably in retrograde traffic of cytosolic double-membrane vesicles derived from both, early and possibly late endosomes/PVC (prevacuolar compartment) back to the trans-Golgi network (TGN or late Golgi). It has been reported to function both as a (target membrane) t-SNARE and as a (vesicle) v-SNARE. Upon vesicle tethering to the target membrane, which requires additional proteins, a SNARE-pin is formed. This is a very stable 4 parallel alpha-helical coil bundle consisting of 4 SNARE domains (usually one of each type: Qa, Qb, Qc, and R), of which at least one is anchored in the opposite membrane. The formation of the SNARE-pin is believed to bring the two membranes in close proximity and to provide the energy to drive membrane fusion. Through its interaction with the VFT (or GARP) complex, it may also contribute to vesicle recognition specificity and tethering. Regulation of SNARE-pin formation also seems to depend on the phosphorylation state of the protein, phosphorylation by TPK1 causing inhibition and dephosphorylation by SIT4 activation., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT92", "ec_number_list": [], "go_molecular_function": "GO:0000149 SNARE binding;GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005768 endosome;GO:0005829 cytosol;GO:0012505 endomembrane system;GO:0031902 late endosome membrane", "go_biological_process": "GO:0048210 Golgi vesicle fusion to target membrane;GO:0006886 intracellular protein transport;GO:0006897 endocytosis;GO:0042147 retrograde transport, endosome to Golgi;GO:0006895 Golgi to endosome transport", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q03322-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03327-1", "uniprot_id": [ { "id": "UGO1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03327", "type": "external" } ], "mass": 57543.0, "length": 502, "protein_name": "Mitochondrial fusion and transport protein UGO1", "gene_name": "UGO1", "organism": "Yeast", "refseq_name": "mitofusin complex protein UGO1", "refseq_ac": [ { "id": "NP_010758", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010758", "type": "external" } ], "gene_names_uniprotkb": "UGO1", "gene_names_refseq": "UGO1", "protein_names_uniprotkb": "Mitochondrial fusion and transport protein UGO1", "protein_names_refseq": "mitofusin complex protein UGO1", "tax_id": 559292, "disease": "Leigh disease (Disease Ontology:DOID:3652)", "pathway": " (sce:YDR470C); (R-SCE-199220)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10930523;11257114;12566426;12808034;14576278;15087460;22814378;23749301;24374639;33481703;9169867", "class_list": "", "function": "Required for mitochondrial fusion as well as normal mitochondrial morphology by bridging the essential interaction between FZO1 and MGM1. May coordinate fusion of inner and outer membranes during mitochondrial fusion., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT94", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0008053 mitochondrial fusion;GO:1990626 mitochondrial outer membrane fusion;GO:1990627 mitochondrial inner membrane fusion", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q03327-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03337-1", "uniprot_id": [ { "id": "TRS31_YEAST", "url": "https://www.uniprot.org/uniprot/Q03337", "type": "external" } ], "mass": 31722.0, "length": 283, "protein_name": "Trafficking protein particle complex subunit 31", "gene_name": "TRS31", "organism": "Yeast", "refseq_name": "TRAPP subunit TRS31", "refseq_ac": [ { "id": "NP_010760", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010760", "type": "external" } ], "gene_names_uniprotkb": "TRS31", "gene_names_refseq": "TRS31", "protein_names_uniprotkb": "Trafficking protein particle complex subunit 31; TRAPP subunit 31; Transport protein particle 31 kDa subunit", "protein_names_refseq": "TRAPP subunit TRS31", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR472W); (R-SCE-204005); (R-SCE-8876198)", "pathway_count": 3, "publication_count": 17, "publication_id_list": "11239471;14562106;18407956;19779198;20375281;20702584;20972447;21126336;23749301;24374639;30516470;32597660;33229814;33481703;33491328;9169867;9564032", "class_list": "", "function": "Component of the TRAPP I, TRAPP II and TRAPP III complexes which act as guanine nucleotide exchange factors (GEF) for YPT1. TRAPP I plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. TRAPP II plays a role in intra-Golgi transport. TRAPP III plays a role in autophagosome formation., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 17, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 17, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 17, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 16, "binding_glycan_count": 0, "secondary_ac_list": "D6VT96", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0000407 phagophore assembly site;GO:1990072 TRAPPIII protein complex;GO:1990070 TRAPPI protein complex", "go_biological_process": "GO:0016236 macroautophagy;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0042147 retrograde transport, endosome to Golgi;GO:0006891 intra-Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 3.6, "record_id": "Q03337-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03433-1", "uniprot_id": [ { "id": "VPS71_YEAST", "url": "https://www.uniprot.org/uniprot/Q03433", "type": "external" } ], "mass": 32021.0, "length": 280, "protein_name": "Vacuolar protein sorting-associated protein 71", "gene_name": "VPS71", "organism": "Yeast", "refseq_name": "Vps71p", "refseq_ac": [ { "id": "NP_013671", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013671", "type": "external" } ], "gene_names_uniprotkb": "VPS71; SWC6; YM8054.02C", "gene_names_refseq": "SWC6; VPS71", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 71; SWR complex protein 6", "protein_names_refseq": "Vps71p", "tax_id": 559292, "disease": "", "pathway": " (sce:YML041C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12134085;14562095;14645854;14690608;15045029;24374639;33491328;9169872", "class_list": "", "function": "Participates in the catalytic exchange of histone H2A for the H2A variant HZT1, an euchromatin-specific factor, leading to chromatin remodeling and changes in transcription of targeted genes. Indirectly involved in vacuolar protein sorting., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZD4", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0031491 nucleosome binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0000812 Swr1 complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006355 regulation of DNA-templated transcription;GO:0006623 protein targeting to vacuole", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q03433-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03579-1", "uniprot_id": [ { "id": "LIP1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03579", "type": "external" } ], "mass": 17207.0, "length": 150, "protein_name": "Ceramide synthase subunit LIP1", "gene_name": "LIP1", "organism": "Yeast", "refseq_name": "sphingosine N-acyltransferase subunit LIP1", "refseq_ac": [ { "id": "NP_014027", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014027", "type": "external" } ], "gene_names_uniprotkb": "LIP1", "gene_names_refseq": "LIP1", "protein_names_uniprotkb": "Ceramide synthase subunit LIP1; LAG1/LAC1-interacting protein 1", "protein_names_refseq": "sphingosine N-acyltransferase subunit LIP1", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR298W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "15692566;19795423;19823750;24374639;32597660;33481703;33491328;34492164;37953642;38964337;39528796;9169872", "class_list": "", "function": "Component of the ceramide synthase complex required for the synthesis of ceramides (PubMed:15692566, PubMed:34492164, PubMed:37953642, PubMed:39528796). Plays a role in the localization of LAG1 to the nuclear endoplasmic reticulum (PubMed:34492164)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 18, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0C5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0061576 acyl-CoA ceramide synthase complex", "go_biological_process": "GO:0046513 ceramide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q03579-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03630-1", "uniprot_id": [ { "id": "BET5_YEAST", "url": "https://www.uniprot.org/uniprot/Q03630", "type": "external" } ], "mass": 18434.0, "length": 159, "protein_name": "Trafficking protein particle complex subunit BET5", "gene_name": "BET5", "organism": "Yeast", "refseq_name": "TRAPP subunit BET5", "refseq_ac": [ { "id": "NP_013634", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013634", "type": "external" } ], "gene_names_uniprotkb": "BET5", "gene_names_refseq": "BET5", "protein_names_uniprotkb": "Trafficking protein particle complex subunit BET5; TRAPP subunit BET5; Transport protein particle 18 kDa subunit", "protein_names_refseq": "TRAPP subunit BET5", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162); melanoma (Disease Ontology:DOID:1909)", "pathway": " (sce:YML077W); (R-SCE-204005); (R-SCE-6798695); (R-SCE-8876198)", "pathway_count": 4, "publication_count": 8, "publication_id_list": "11239471;17322287;20375281;20972447;24374639;9169872;9564032;9611195", "class_list": "", "function": "Component of the TRAPP I, TRAPP II and TRAPP III complexes which act as guanine nucleotide exchange factors (GEF) for YPT1. TRAPP I plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. TRAPP II plays a role in intra-Golgi transport. TRAPP III plays a role in autophagosome formation. Required for sporulation. Has a role late in meiosis following DNA replication., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0K6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0000407 phagophore assembly site;GO:1990072 TRAPPIII protein complex;GO:1990070 TRAPPI protein complex", "go_biological_process": "GO:0016236 macroautophagy;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0042147 retrograde transport, endosome to Golgi;GO:0006891 intra-Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q03630-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03654-1", "uniprot_id": [ { "id": "CEF1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03654", "type": "external" } ], "mass": 67731.0, "length": 590, "protein_name": "Pre-mRNA-splicing factor CEF1", "gene_name": "CEF1", "organism": "Yeast", "refseq_name": "Cef1p", "refseq_ac": [ { "id": "NP_013940", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013940", "type": "external" } ], "gene_names_uniprotkb": "CEF1; NTC85; YM8261.07", "gene_names_refseq": "CEF1; NTC85", "protein_names_uniprotkb": "Pre-mRNA-splicing factor CEF1; PRP nineteen-associated complex protein 85; PRP19-associated complex protein 85", "protein_names_refseq": "Cef1p", "tax_id": 559292, "disease": "alcohol use disorder (Disease Ontology:DOID:1574); osteosarcoma (Disease Ontology:DOID:3347); esophagus adenocarcinoma (Disease Ontology:DOID:4914)", "pathway": " (sce:YMR213W)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "10092627;10570151;11018040;11102353;11784857;11884590;12088152;14562095;14562106;14690591;17322287;19779198;19795423;19823750;23749301;24374639;30516470;32597660;33481703;33491328;9169872;9528791;9632794", "class_list": "", "function": "Involved in pre-mRNA splicing and cell cycle control. Required for the binding of the NTC complex (or PRP19-associated complex) components to the spliceosome to mediate conformational rearrangement or to stabilize the structure of the spliceosome after U4 snRNA dissociation, which leads to spliceosome maturation. Its absence leads to an arrest of the cell cycle, possibly due to the inefficient splicing of TUB1., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W038;Q6B1D8", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005681 spliceosomal complex;GO:0071006 U2-type catalytic step 1 spliceosome;GO:0000974 Prp19 complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0000350 generation of catalytic spliceosome for second transesterification step", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "Q03654-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03656-1", "uniprot_id": [ { "id": "SKY1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03656", "type": "external" } ], "mass": 83238.0, "length": 742, "protein_name": "Serine/threonine-protein kinase SKY1", "gene_name": "SKY1", "organism": "Yeast", "refseq_name": "serine/threonine protein kinase SKY1", "refseq_ac": [ { "id": "NP_013943", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013943", "type": "external" } ], "gene_names_uniprotkb": "SKY1; YM8261.10C", "gene_names_refseq": "SKY1", "protein_names_uniprotkb": "Serine/threonine-protein kinase SKY1; 2.7.11.1; SRPK", "protein_names_refseq": "serine/threonine protein kinase SKY1", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR216C)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "11175909;12911299;14562106;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21177495;23749301;24374639;30516470;32597660;33229814;33481703;33491328;9169872", "class_list": "", "function": "Constitutively active kinase, specifically and sequentially phosphorylates serine/arginine (SR)-type shuttling mRNA binding proteins in their RS dipeptide repeats., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 19, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 19, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 19, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 49, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 18, "binding_glycan_count": 0, "secondary_ac_list": "D6W041", "ec_number_list": [ { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.1.26.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.26.-", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.67", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0042307 positive regulation of protein import into nucleus;GO:0009410 response to xenobiotic stimulus;GO:0006873 intracellular monoatomic ion homeostasis;GO:0030003 intracellular monoatomic cation homeostasis;GO:0006376 mRNA splice site recognition", "synthesized_glycan_count": 0, "hit_score": 4.3, "record_id": "Q03656-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03660-1", "uniprot_id": [ { "id": "TR130_YEAST", "url": "https://www.uniprot.org/uniprot/Q03660", "type": "external" } ], "mass": 128131.0, "length": 1102, "protein_name": "Trafficking protein particle complex II-specific subunit 130", "gene_name": "TRS130", "organism": "Yeast", "refseq_name": "transport protein particle complex II subunit TRS130", "refseq_ac": [ { "id": "NP_013945", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013945", "type": "external" } ], "gene_names_uniprotkb": "TRS130; YM8261.12C", "gene_names_refseq": "TRS130", "protein_names_uniprotkb": "Trafficking protein particle complex II-specific subunit 130; TRAPP II-specific subunit 130; Transport protein particle 130 kDa subunit", "protein_names_refseq": "transport protein particle complex II subunit TRS130", "tax_id": 559292, "disease": "agnathia-otocephaly complex (Disease Ontology:DOID:0060341); velocardiofacial syndrome (Disease Ontology:DOID:12583)", "pathway": " (sce:YMR218C); (R-SCE-204005); (R-SCE-8876198)", "pathway_count": 3, "publication_count": 12, "publication_id_list": "10727015;11239471;12478387;14562106;16314430;17475775;20972447;23078654;24374639;33491328;9169872;9564032", "class_list": "", "function": "Specific subunit of the TRAPP II complex, a highly conserved vesicle tethering complex that functions in the late Golgi as a guanine nucleotide exchange factor (GEF) for the Golgi YPT1 GTPase. TRS130 plays a role in the YPT GEF activity of TRAPP II in concert with the two other TRAPP II-specific subunits TRS65 and TRS120. Required for both the cytoplasm-to-vacuole targeting (Cvt) pathway and starvation-induced autophagy through its role in ATG8 and ATG9 trafficking., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W043", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005769 early endosome;GO:0005829 cytosol;GO:0005802 trans-Golgi network;GO:1990071 TRAPPII protein complex", "go_biological_process": "GO:0016236 macroautophagy;GO:0042147 retrograde transport, endosome to Golgi;GO:0032258 cytoplasm to vacuole targeting by the Cvt pathway;GO:0006891 intra-Golgi vesicle-mediated transport;GO:0034498 early endosome to Golgi transport", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q03660-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03694-1", "uniprot_id": [ { "id": "INP1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03694", "type": "external" } ], "mass": 47315.0, "length": 420, "protein_name": "Inheritance of peroxisomes protein 1", "gene_name": "INP1", "organism": "Yeast", "refseq_name": "Inp1p", "refseq_ac": [ { "id": "NP_013931", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013931", "type": "external" } ], "gene_names_uniprotkb": "INP1; YM8325.05C", "gene_names_refseq": "INP1", "protein_names_uniprotkb": "Inheritance of peroxisomes protein 1", "protein_names_refseq": "Inp1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR204C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562095;14562106;15665377;15928207;16678774;17330950;19779198;24374639;32597660;33481703;33491328;9169872", "class_list": "", "function": "Required for peroxisome inheritance., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W029", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005777 peroxisome;GO:0005780 extrinsic component of intraperoxisomal membrane", "go_biological_process": "GO:0045033 peroxisome inheritance", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q03694-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03735-1", "uniprot_id": [ { "id": "NAB6_YEAST", "url": "https://www.uniprot.org/uniprot/Q03735", "type": "external" } ], "mass": 126139.0, "length": 1134, "protein_name": "RNA-binding protein NAB6", "gene_name": "NAB6", "organism": "Yeast", "refseq_name": "Nab6p", "refseq_ac": [ { "id": "NP_013589", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013589", "type": "external" } ], "gene_names_uniprotkb": "NAB6; YM8339.02", "gene_names_refseq": "NAB6", "protein_names_uniprotkb": "RNA-binding protein NAB6; Nucleic acid-binding protein 6", "protein_names_refseq": "Nab6p", "tax_id": 559292, "disease": "", "pathway": " (sce:YML117W)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "14562095;14562106;14570984;17330950;17563356;18407956;18959479;19779198;20702584;21126336;21177495;22814378;23749301;24374639;24909858;30516470;32597660;33229814;33481703;33491328;9169872", "class_list": "", "function": "RNA-binding protein that associates with mRNAs encoding cell wall proteins., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 6, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 6, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 6, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 34, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "D6W0G7", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0003730 mRNA 3'-UTR binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0070935 3'-UTR-mediated mRNA stabilization;GO:1990394 cellular response to cell wall damage", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "Q03735-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03761-1", "uniprot_id": [ { "id": "TAF12_YEAST", "url": "https://www.uniprot.org/uniprot/Q03761", "type": "external" } ], "mass": 61073.0, "length": 539, "protein_name": "SAGA complex/transcription factor TFIID complex subunit TAF12", "gene_name": "TAF12", "organism": "Yeast", "refseq_name": "Taf12p", "refseq_ac": [ { "id": "NP_010429", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010429", "type": "external" } ], "gene_names_uniprotkb": "TAF12; TAF61; TAF68; YD8358.02", "gene_names_refseq": "TAF12; TAF61; TAF68", "protein_names_uniprotkb": "SAGA complex/transcription factor TFIID complex subunit TAF12; TAFII-61; TAFII-68; TAFII61; TAFII68; TBP-associated factor 12; TBP-associated factor 61 kDa; Transcription initiation factor TFIID subunit 12", "protein_names_refseq": "Taf12p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR145W); (R-SCE-674695); (R-SCE-73776); (R-SCE-73779); (R-SCE-75953); (R-SCE-76042)", "pathway_count": 6, "publication_count": 47, "publication_id_list": "10026213;10751405;10788514;10864329;11238921;11295558;11473260;12052880;12093743;12138208;12186975;12446794;12501245;12516863;12840001;14562095;14562106;15260971;15448131;15647753;15665377;17330950;17563356;18407956;19731963;19779198;19795423;19823750;20190278;20702584;21126336;21734642;22218487;22814378;23749301;24374639;25216679;28918903;31969703;32597660;33229814;33481703;33491328;33864814;9169867;9674426;9695952", "class_list": "", "function": "Functions as a component of both the DNA-binding general transcription initiation factor complex TFIID and the transcription coactivator SAGA complex (PubMed:10788514, PubMed:12052880, PubMed:12138208, PubMed:25216679). Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription (PubMed:10751405, PubMed:11238921, PubMed:12516863, PubMed:15448131). SAGA acts as a general cofactor required for essentially all RNA polymerase II transcription (PubMed:10864329, PubMed:25216679, PubMed:9674426). At the promoters, SAGA is required for transcription pre-initiation complex (PIC) recruitment. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (via core/TAF module) and promoter selectivity, interaction with transcription activators (via Tra1/SPT module), and chromatin modification through histone acetylation (via HAT module) and deubiquitination (via DUB module) (PubMed:12501245, PubMed:12840001, PubMed:31969703). SAGA preferentially acetylates histones H3 (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac) and H2B and deubiquitinates histone H2B (PubMed:10026213). SAGA interacts with DNA via upstream activating sequences (UASs) (PubMed:28918903). Also identified in a modified version of SAGA named SALSA or SLIK (PubMed:12186975, PubMed:12446794). The cleavage of SPT7 and the absence of the SPT8 subunit in SLIK neither drive any major conformational differences in its structure compared with SAGA, nor significantly affect HAT, DUB, or DNA-binding activities (PubMed:33864814)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 14, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 14, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 14, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 20, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 13, "binding_glycan_count": 0, "secondary_ac_list": "D6VSC8", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0042802 identical protein binding;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005777 peroxisome;GO:0005669 transcription factor TFIID complex;GO:0000124 SAGA complex;GO:0046695 SLIK (SAGA-like) complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006325 chromatin organization;GO:0006366 transcription by RNA polymerase II;GO:0051123 RNA polymerase II preinitiation complex assembly", "synthesized_glycan_count": 0, "hit_score": 6.3, "record_id": "Q03761-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03780-1", "uniprot_id": [ { "id": "YD239_YEAST", "url": "https://www.uniprot.org/uniprot/Q03780", "type": "external" } ], "mass": 86433.0, "length": 787, "protein_name": "Uncharacterized protein YDR239C", "gene_name": "", "organism": "Yeast", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_010525", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010525", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein YDR239C", "protein_names_refseq": "uncharacterized protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR239C)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "14562095;14562106;17322287;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21177495;22218487;22814378;23749301;24374639;32597660;33229814;33481703;33491328;34965436;9169867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 12, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 12, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 12, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 86, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 11, "binding_glycan_count": 0, "secondary_ac_list": "D6VSM0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 3.7, "record_id": "Q03780-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03784-1", "uniprot_id": [ { "id": "TRS23_YEAST", "url": "https://www.uniprot.org/uniprot/Q03784", "type": "external" } ], "mass": 24863.0, "length": 219, "protein_name": "Trafficking protein particle complex subunit 23", "gene_name": "TRS23", "organism": "Yeast", "refseq_name": "TRAPP subunit TRS23", "refseq_ac": [ { "id": "NP_010532", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010532", "type": "external" } ], "gene_names_uniprotkb": "TRS23; YD8419.13", "gene_names_refseq": "TRS23", "protein_names_uniprotkb": "Trafficking protein particle complex subunit 23; TRAPP subunit 23; Transport protein particle 23 kDa subunit", "protein_names_refseq": "TRAPP subunit TRS23", "tax_id": 559292, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888)", "pathway": " (sce:YDR246W); (R-SCE-204005); (R-SCE-8876198)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "11239471;11805826;14562106;20375281;20972447;24374639;9169867;9564032", "class_list": "", "function": "Component of the TRAPP I, TRAPP II and TRAPP III complexes which act as guanine nucleotide exchange factors (GEF) for YPT1. TRAPP I plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. TRAPP II plays a role in intra-Golgi transport. TRAPP III plays a role in autophagosome formation., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSM6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0000407 phagophore assembly site;GO:1990072 TRAPPIII protein complex;GO:1990070 TRAPPI protein complex", "go_biological_process": "GO:0016236 macroautophagy;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0042147 retrograde transport, endosome to Golgi;GO:0006891 intra-Golgi vesicle-mediated transport;GO:0051276 chromosome organization", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q03784-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03790-1", "uniprot_id": [ { "id": "NUP53_YEAST", "url": "https://www.uniprot.org/uniprot/Q03790", "type": "external" } ], "mass": 52619.0, "length": 475, "protein_name": "Nucleoporin NUP53", "gene_name": "NUP53", "organism": "Yeast", "refseq_name": "FG-nucleoporin NUP53", "refseq_ac": [ { "id": "NP_013873", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013873", "type": "external" } ], "gene_names_uniprotkb": "NUP53; YM8520.02", "gene_names_refseq": "NUP53", "protein_names_uniprotkb": "Nucleoporin NUP53; Nuclear pore protein NUP53", "protein_names_refseq": "FG-nucleoporin NUP53", "tax_id": 559292, "disease": "intestinal pseudo-obstruction (Disease Ontology:DOID:0080072)", "pathway": " (sce:YMR153W)", "pathway_count": 1, "publication_count": 28, "publication_id_list": "10684247;10688190;11283351;11352933;12403813;12473689;12604785;12791264;14562106;14574415;14697200;17330950;17461799;17563356;18407956;19779198;19795423;19823750;21126336;22814378;23749301;24374639;32597660;33229814;33481703;33491328;9169872;9864357", "class_list": "", "function": "Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm). NUP53 may play an important role in cell cycle regulation by inhibiting PSE1 transport functions during mitosis and sequestration of MAD1-MAD2 in a cell cycle-dependent manner. It also seems to play an important role in de novo NPC assembly by associating with nuclear membranes and driving their proliferation., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 5, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 5, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 5, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 29, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VZX4", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0042802 identical protein binding;GO:0003697 single-stranded DNA binding;GO:0017056 structural constituent of nuclear pore", "go_cellular_component": "GO:0044615 nuclear pore nuclear basket;GO:0005635 nuclear envelope;GO:0005643 nuclear pore;GO:0031965 nuclear membrane;GO:0044613 nuclear pore central transport channel", "go_biological_process": "GO:0006999 nuclear pore organization;GO:0006913 nucleocytoplasmic transport;GO:0051301 cell division;GO:0045893 positive regulation of DNA-templated transcription;GO:0007088 regulation of mitotic nuclear division", "synthesized_glycan_count": 0, "hit_score": 3.5, "record_id": "Q03790-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03941-1", "uniprot_id": [ { "id": "CAB5_YEAST", "url": "https://www.uniprot.org/uniprot/Q03941", "type": "external" } ], "mass": 27340.0, "length": 241, "protein_name": "Dephospho-CoA kinase CAB5", "gene_name": "CAB5", "organism": "Yeast", "refseq_name": "putative dephospho-CoA kinase", "refseq_ac": [ { "id": "NP_010482", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010482", "type": "external" } ], "gene_names_uniprotkb": "CAB5; YD9346.07C", "gene_names_refseq": "CAB5", "protein_names_uniprotkb": "Dephospho-CoA kinase CAB5; 2.7.1.24; DPCK; Dephosphocoenzyme A kinase", "protein_names_refseq": "putative dephospho-CoA kinase", "tax_id": 559292, "disease": "neurodegeneration with brain iron accumulation 6 (Disease Ontology:DOID:0110740)", "pathway": " (sce:YDR196C); (R-SCE-196783)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "14562106;14690591;16823961;17322287;19266201;23749301;24374639;33491328;9169867", "class_list": "", "function": "Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSH9", "ec_number_list": [ { "id": "2.7.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.24", "type": "external" } ], "go_molecular_function": "GO:0004140 dephospho-CoA kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0031315 extrinsic component of mitochondrial outer membrane;GO:0005635 nuclear envelope;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005811 lipid droplet", "go_biological_process": "GO:0015937 coenzyme A biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q03941-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03954-1", "uniprot_id": [ { "id": "SPC19_YEAST", "url": "https://www.uniprot.org/uniprot/Q03954", "type": "external" } ], "mass": 18910.0, "length": 165, "protein_name": "DASH complex subunit SPC19", "gene_name": "SPC19", "organism": "Yeast", "refseq_name": "Spc19p", "refseq_ac": [ { "id": "NP_010487", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010487", "type": "external" } ], "gene_names_uniprotkb": "SPC19", "gene_names_refseq": "SPC19", "protein_names_uniprotkb": "DASH complex subunit SPC19; 19 kDa spindle pole component protein; Outer kinetochore protein SPC19", "protein_names_refseq": "Spc19p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR201W)", "pathway_count": 1, "publication_count": 25, "publication_id_list": "11782438;11799062;12408861;14562095;14562106;15640796;15664196;16415853;16715078;16777964;17322287;17460120;17643123;18079178;18407956;19779198;21177495;22218487;23749301;24374639;25236177;33481703;33491328;36701236;9169867", "class_list": "", "function": "Component of the DASH complex that connects microtubules with kinetochores and couples microtubule depolymerization to chromosome movement; it is involved in retrieving kinetochores to the spindle poles before their re-orientation on the spindle in early mitosis and allows microtubule depolymerization to pull chromosomes apart and resist detachment during anaphase (PubMed:15664196, PubMed:16415853, PubMed:16777964, PubMed:17460120, PubMed:17643123). Kinetochores, consisting of a centromere-associated inner segment and a microtubule-contacting outer segment, play a crucial role in chromosome segregation by mediating the physical connection between centromeric DNA and microtubules (PubMed:11782438). Kinetochores also serve as an input point for the spindle assembly checkpoint, which delays anaphase until all chromosomes have bioriented on the mitotic spindle (PubMed:11782438, PubMed:12408861). During spindle-kinetochore attachment, kinetochores first attach to the lateral surface of spindle microtubules, which supports the congression of chromosomes toward the middle of the dividing cell; they then slide along towards the spindle pole, a process independent of the DASH complex but requiring the NDC80 complex (PubMed:25236177). When the end of a disassembling microtubule reaches the laterally attached kinetochore, the DASH complex together with the NDC80 complex and STU2 convert lateral attachment to end-on capture to produce a structure that can track with microtubule shortening and sustain attachment when tension is applied across sister kinetochores upon their biorientation (PubMed:15640796, PubMed:15664196, PubMed:25236177). Microtubule depolymerization proceeds by protofilament splaying and induces the kinetochore-attached DASH complex to slide longitudinally, thereby helping to transduce depolymerization energy into pulling forces to disjoin chromatids (PubMed:16415853, PubMed:16777964). Incorrect microtubule attachments are corrected by releasing microubules from the kinetochore through phosphorylation by IPL1 of kinetochore components (PubMed:12408861). Links the microtubule cytoskeleton to chromosomes during interphase (PubMed:36701236). Also contributes to the poleward transport of kinetochores on microtubules following centromeric DNA replication in S-phase (PubMed:18079178)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSI3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005876 spindle microtubule;GO:0072686 mitotic spindle;GO:0042729 DASH complex", "go_biological_process": "GO:0008608 attachment of spindle microtubules to kinetochore;GO:0051301 cell division;GO:0031116 positive regulation of microtubule polymerization;GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore;GO:1990758 mitotic sister chromatid biorientation", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "Q03954-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q04003-1", "uniprot_id": [ { "id": "SAS4_YEAST", "url": "https://www.uniprot.org/uniprot/Q04003", "type": "external" } ], "mass": 55409.0, "length": 481, "protein_name": "Something about silencing protein 4", "gene_name": "SAS4", "organism": "Yeast", "refseq_name": "Sas4p", "refseq_ac": [ { "id": "NP_010467", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010467", "type": "external" } ], "gene_names_uniprotkb": "SAS4; YD9395.15C", "gene_names_refseq": "SAS4", "protein_names_uniprotkb": "Something about silencing protein 4", "protein_names_refseq": "Sas4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR181C)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "10471696;10471697;11404324;11731479;11731480;12626510;14562106;15665377;16079223;18407956;21126336;21177495;22814378;23749301;24374639;30516470;32597660;33481703;33491328;9169867", "class_list": "", "function": "Component of the SAS complex, a multiprotein complex that acetylates 'Lys-16' of histone H4 and 'Lys-14' of histone H3. The SAS complex is however unable to acetylate nucleosomal histones. The complex is involved in transcriptional silencing at telomeres and at HML locus. Also involved in rDNA silencing. In the complex, SAS4 is essential for histone acetyltransferase (HAT) activity of the complex., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSG4", "ec_number_list": [], "go_molecular_function": "GO:0004402 histone acetyltransferase activity;GO:0016407 acetyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0000781 chromosome, telomeric region;GO:0033255 SAS acetyltransferase complex", "go_biological_process": "GO:0031509 subtelomeric heterochromatin formation;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q04003-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q04062-1", "uniprot_id": [ { "id": "RPN9_YEAST", "url": "https://www.uniprot.org/uniprot/Q04062", "type": "external" } ], "mass": 45782.0, "length": 393, "protein_name": "26S proteasome regulatory subunit RPN9", "gene_name": "RPN9", "organism": "Yeast", "refseq_name": "proteasome regulatory particle lid subunit RPN9", "refseq_ac": [ { "id": "NP_010715", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010715", "type": "external" } ], "gene_names_uniprotkb": "RPN9; D9461.14; NAS7", "gene_names_refseq": "NAS7; RPN9", "protein_names_uniprotkb": "26S proteasome regulatory subunit RPN9; Proteasome non-ATPase subunit 7", "protein_names_refseq": "proteasome regulatory particle lid subunit RPN9", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR427W); (R-SCE-1236978); (R-SCE-5668541); (R-SCE-5689880); (R-SCE-6798695); (R-SCE-9907900)", "pathway_count": 6, "publication_count": 11, "publication_id_list": "12504901;14562106;19795423;19823750;21126336;22814378;22927375;24374639;33491328;9169867;9714768", "class_list": "", "function": "Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT56", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0034515 proteasome storage granule;GO:0005634 nucleus;GO:0005829 cytosol;GO:0008541 proteasome regulatory particle, lid subcomplex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0043248 proteasome assembly", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q04062-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q04177-1", "uniprot_id": [ { "id": "UTP5_YEAST", "url": "https://www.uniprot.org/uniprot/Q04177", "type": "external" } ], "mass": 72002.0, "length": 643, "protein_name": "U3 small nucleolar RNA-associated protein 5", "gene_name": "UTP5", "organism": "Yeast", "refseq_name": "Utp5p", "refseq_ac": [ { "id": "NP_010686", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010686", "type": "external" } ], "gene_names_uniprotkb": "UTP5; D9509.17", "gene_names_refseq": "UTP5", "protein_names_uniprotkb": "U3 small nucleolar RNA-associated protein 5; U three protein 5; U3 protein 5 required for transcription; U3 snoRNA-associated protein 5; t-UTP5", "protein_names_refseq": "Utp5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR398W); (R-SCE-6791226)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "12068309;14562106;15489292;18407956;19684113;19795423;19823750;21126336;23749301;24374639;33481703;33491328;9169867", "class_list": "", "function": "Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT31", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0033553 rDNA heterochromatin;GO:0034455 t-UTP complex;GO:0032040 small-subunit processome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045943 positive regulation of transcription by RNA polymerase I;GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q04177-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q04182-1", "uniprot_id": [ { "id": "PDR15_YEAST", "url": "https://www.uniprot.org/uniprot/Q04182", "type": "external" } ], "mass": 172256.0, "length": 1529, "protein_name": "ATP-dependent permease PDR15", "gene_name": "PDR15", "organism": "Yeast", "refseq_name": "ATP-binding cassette multidrug transporter PDR15", "refseq_ac": [ { "id": "NP_010694", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010694", "type": "external" } ], "gene_names_uniprotkb": "PDR15; D9509.24", "gene_names_refseq": "PDR15", "protein_names_uniprotkb": "ATP-dependent permease PDR15", "protein_names_refseq": "ATP-binding cassette multidrug transporter PDR15", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR406W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12529331;16847258;18407956;24374639;32597660;33481703;33491328;9169867", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VT38", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0016020 membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0009410 response to xenobiotic stimulus;GO:1990961 xenobiotic detoxification by transmembrane export across the plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q04182-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q04322-1", "uniprot_id": [ { "id": "GYL1_YEAST", "url": "https://www.uniprot.org/uniprot/Q04322", "type": "external" } ], "mass": 82131.0, "length": 720, "protein_name": "Probable GTPase-activating protein GYL1", "gene_name": "GYL1", "organism": "Yeast", "refseq_name": "Gyl1p", "refseq_ac": [ { "id": "NP_013917", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013917", "type": "external" } ], "gene_names_uniprotkb": "GYL1; APP2; YM9646.04", "gene_names_refseq": "APP2; GYL1", "protein_names_uniprotkb": "Probable GTPase-activating protein GYL1; GYP5-like protein 1", "protein_names_refseq": "Gyl1p", "tax_id": 559292, "disease": "acanthosis nigricans (Disease Ontology:DOID:3138)", "pathway": " (sce:YMR192W)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "14562106;15331637;15542864;15802519;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;22218487;22814378;23749301;24374639;24909858;32597660;33481703;33491328;9169872", "class_list": "", "function": "Probable GTPase-activating protein which stimulates the GTP hydrolysis rate by GYP5 of YPT1 and SEC4. Involved in ER to Golgi trafficking and polarized exocytosis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 25, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W016", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005798 Golgi-associated vesicle;GO:0005886 plasma membrane;GO:0000131 incipient cellular bud site", "go_biological_process": "GO:0015031 protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006887 exocytosis;GO:0017157 regulation of exocytosis", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "Q04322-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q04338-1", "uniprot_id": [ { "id": "VTI1_YEAST", "url": "https://www.uniprot.org/uniprot/Q04338", "type": "external" } ], "mass": 24668.0, "length": 217, "protein_name": "t-SNARE VTI1", "gene_name": "VTI1", "organism": "Yeast", "refseq_name": "v-SNARE protein VTI1", "refseq_ac": [ { "id": "NP_013924", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013924", "type": "external" } ], "gene_names_uniprotkb": "VTI1; YM9646.10C", "gene_names_refseq": "VTI1", "protein_names_uniprotkb": "t-SNARE VTI1; Qb-SNARE VTI1; VPS10-interacting protein 1; Vesicle transport v-SNARE protein VTI1", "protein_names_refseq": "v-SNARE protein VTI1", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR197C); (R-SCE-114608); (R-SCE-6811440)", "pathway_count": 3, "publication_count": 17, "publication_id_list": "10359592;10385523;11739407;12453154;14981247;18407956;19779198;21126336;24374639;33481703;33491328;34965436;9169872;9199167;9398683;9427746;9446565", "class_list": "", "function": "t-SNARE found in various SNARE complexes involved in multiple transport pathways. The composition of the t-SNARE complexes is specific for a limited number of v-SNAREs and therefore allows only the vesicles carrying the matching v-SNARE to fuse., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 8, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W022", "ec_number_list": [], "go_molecular_function": "GO:0000149 SNARE binding;GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0000421 autophagosome membrane;GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0048210 Golgi vesicle fusion to target membrane;GO:0042144 vacuole fusion, non-autophagic;GO:0006886 intracellular protein transport;GO:0006897 endocytosis;GO:0016236 macroautophagy", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q04338-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q04373-1", "uniprot_id": [ { "id": "PUF6_YEAST", "url": "https://www.uniprot.org/uniprot/Q04373", "type": "external" } ], "mass": 75106.0, "length": 656, "protein_name": "Pumilio homology domain family member 6", "gene_name": "PUF6", "organism": "Yeast", "refseq_name": "Puf6p", "refseq_ac": [ { "id": "NP_010784", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010784", "type": "external" } ], "gene_names_uniprotkb": "PUF6; D9719.2", "gene_names_refseq": "PUF6", "protein_names_uniprotkb": "Pumilio homology domain family member 6", "protein_names_refseq": "Puf6p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR496C)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "14562095;14562106;15198983;17287358;17330950;18407956;18413716;18791219;19244342;19684113;19779198;19795423;19823750;20702584;21126336;22218487;22814378;23749301;24374639;30516470;33229814;33481703;33491328;9169867", "class_list": "", "function": "RNA-binding protein involved in post-transcriptional regulation. Component of the ASH1 mRNP which transports the ASH1 mRNA to the distal tip of the bud, where the ASH1 protein is translated and targeted to the daughter cell nucleus. Binds to the ASH1 3'-UTR containing the PUF consensus UUGU segment and represses its translation. This silencing of ASH1 mRNA is critical for asymmetric seggregation of ASH1 to the daughter cell nucleus., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 20, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VTB8", "ec_number_list": [], "go_molecular_function": "GO:0000900 mRNA regulatory element binding translation repressor activity;GO:0003729 mRNA binding;GO:0003730 mRNA 3'-UTR binding;GO:0048027 mRNA 5'-UTR binding;GO:0070180 large ribosomal subunit rRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor;GO:0015934 large ribosomal subunit;GO:0101031 protein folding chaperone complex", "go_biological_process": "GO:0006417 regulation of translation;GO:0042273 ribosomal large subunit biogenesis;GO:0050821 protein stabilization;GO:0017148 negative regulation of translation", "synthesized_glycan_count": 0, "hit_score": 3.0, "record_id": "Q04373-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q04377-1", "uniprot_id": [ { "id": "LCD1_YEAST", "url": "https://www.uniprot.org/uniprot/Q04377", "type": "external" } ], "mass": 86425.0, "length": 747, "protein_name": "DNA damage checkpoint protein LCD1", "gene_name": "LCD1", "organism": "Yeast", "refseq_name": "Lcd1p", "refseq_ac": [ { "id": "NP_010787", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010787", "type": "external" } ], "gene_names_uniprotkb": "LCD1; DDC2; PIE1", "gene_names_refseq": "DDC2; LCD1; PIE1", "protein_names_uniprotkb": "DNA damage checkpoint protein LCD1; DNA damage checkpoint protein 2; Lethal, checkpoint-defective, DNA damage-sensitive protein 1", "protein_names_refseq": "Lcd1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR499W)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "10950868;11060031;11154263;11359899;11691833;11707419;11983176;12181334;12791985;14562095;14562106;15369670;16148046;16365046;18407956;19779198;24374639;32597660;33481703;33491328;9169867", "class_list": "", "function": "Forms a complex with the serine/threonine kinase MEC1 which activates checkpoint signaling upon genotoxic stresses. The MEC1-LCD1 complex is recruited by the single-strand-binding protein complex RPA to DNA lesions in order to initiate the DNA repair by homologous recombination, after the MRX-complex and TEL1 are displaced. Required for the recruitment of MEC1 to DNA lesions, the activation of CHK1 and RAD53 kinases and phosphorylation of RAD9 in response to DNA damage. Required for cell growth and meiotic recombination., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTC1", "ec_number_list": [], "go_molecular_function": "GO:0003684 damaged DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000228 nuclear chromosome", "go_biological_process": "GO:0006281 DNA repair;GO:0045184 establishment of protein localization;GO:0006325 chromatin organization;GO:0006139 nucleobase-containing compound metabolic process;GO:0000077 DNA damage checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "Q04377-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q04477-1", "uniprot_id": [ { "id": "SPC24_YEAST", "url": "https://www.uniprot.org/uniprot/Q04477", "type": "external" } ], "mass": 24604.0, "length": 213, "protein_name": "Kinetochore protein SPC24", "gene_name": "SPC24", "organism": "Yeast", "refseq_name": "kinetochore-associated Ndc80 complex subunit SPC24", "refseq_ac": [ { "id": "NP_013835", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013835", "type": "external" } ], "gene_names_uniprotkb": "SPC24; YM9718.16C", "gene_names_refseq": "SPC24", "protein_names_uniprotkb": "Kinetochore protein SPC24", "protein_names_refseq": "kinetochore-associated Ndc80 complex subunit SPC24", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR117C)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "11179222;11266451;11952896;12514103;14562106;15371542;15809444;18407956;19795423;19823750;20489023;21126336;22218487;22814378;23749301;24374639;32597660;33481703;33491328;9169872", "class_list": "", "function": "Acts as a component of the essential kinetochore-associated NDC80 complex, which is involved in chromosome segregation and spindle checkpoint activity., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZU0", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0031262 Ndc80 complex;GO:0005634 nucleus;GO:0000776 kinetochore;GO:0000940 outer kinetochore", "go_biological_process": "GO:0007059 chromosome segregation;GO:0051301 cell division;GO:0031134 sister chromatid biorientation;GO:0098653 centromere clustering", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q04477-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q04660-1", "uniprot_id": [ { "id": "ERB1_YEAST", "url": "https://www.uniprot.org/uniprot/Q04660", "type": "external" } ], "mass": 91705.0, "length": 807, "protein_name": "Ribosome biogenesis protein ERB1", "gene_name": "ERB1", "organism": "Yeast", "refseq_name": "ribosome biogenesis protein ERB1", "refseq_ac": [ { "id": "NP_013764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013764", "type": "external" } ], "gene_names_uniprotkb": "ERB1; YM9796.02C", "gene_names_refseq": "ERB1", "protein_names_uniprotkb": "Ribosome biogenesis protein ERB1; Eukaryotic ribosome biogenesis protein 1", "protein_names_refseq": "ribosome biogenesis protein ERB1", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR049C); (R-SCE-6791226)", "pathway_count": 2, "publication_count": 27, "publication_id_list": "11522832;12110181;14562106;16287855;16888624;17287358;17330950;17563356;18407956;18448671;19779198;19795423;19823750;20702584;21126336;22106047;22218487;23749301;24374639;25880847;26476442;26657628;30516470;32597660;33481703;33491328;9169872", "class_list": "", "function": "Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome., [UniProtKB, HAMAP, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 25, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZM4", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0043021 ribonucleoprotein complex binding;GO:0070180 large ribosomal subunit rRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor;GO:0070545 PeBoW complex", "go_biological_process": "GO:0042273 ribosomal large subunit biogenesis;GO:0006364 rRNA processing;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 2.8, "record_id": "Q04660-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q04749-1", "uniprot_id": [ { "id": "AVO2_YEAST", "url": "https://www.uniprot.org/uniprot/Q04749", "type": "external" } ], "mass": 47139.0, "length": 426, "protein_name": "Target of rapamycin complex 2 subunit AVO2", "gene_name": "AVO2", "organism": "Yeast", "refseq_name": "Avo2p", "refseq_ac": [ { "id": "NP_013784", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013784", "type": "external" } ], "gene_names_uniprotkb": "AVO2; YM9916.07", "gene_names_refseq": "AVO2", "protein_names_uniprotkb": "Target of rapamycin complex 2 subunit AVO2; Adheres voraciously to TOR2 protein 2; TORC2 subunit AVO2", "protein_names_refseq": "Avo2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR068W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "12408816;12631735;14562106;15689497;16002396;17330950;18407956;19779198;21177495;23749301;24374639;29170376;32597660;33481703;33491328;9169872", "class_list": "", "function": "Component of TORC2, which regulates cell cycle-dependent polarization of the actin-cytoskeleton and cell wall integrity. TORC2 controls polarity of the actin cytoskeleton, which is required for orienting the secretory pathway toward discrete growth sites, via the RHO1/PKC1/MAPK cell integrity pathway., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 16, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZP2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005774 vacuolar membrane", "go_biological_process": "GO:0001558 regulation of cell growth;GO:0031929 TOR signaling;GO:0030950 establishment or maintenance of actin cytoskeleton polarity", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q04749-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q04847-1", "uniprot_id": [ { "id": "ROY1_YEAST", "url": "https://www.uniprot.org/uniprot/Q04847", "type": "external" } ], "mass": 64405.0, "length": 553, "protein_name": "Non-SCF-type F-box protein ROY1", "gene_name": "ROY1", "organism": "Yeast", "refseq_name": "Roy1p", "refseq_ac": [ { "id": "NP_013985", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013985", "type": "external" } ], "gene_names_uniprotkb": "ROY1; YM9920.12C", "gene_names_refseq": "ROY1", "protein_names_uniprotkb": "Non-SCF-type F-box protein ROY1; Repressor of YPT52", "protein_names_refseq": "Roy1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR258C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;14562106;17322287;19235764;19652464;19882662;21389113;24374639;33491328;9169872", "class_list": "", "function": "Non-SCF-type F-box protein involved in the endocytic with the vacuolar sorting pathway. Acts as a repressor of YPT52 by inhibiting the formation of active, GTP-bound, YPT52. Involved in the defense mechanism against methylmercury toxicity., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W084", "ec_number_list": [], "go_molecular_function": "GO:0005095 GTPase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0006897 endocytosis;GO:0006623 protein targeting to vacuole", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q04847-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q04924-1", "uniprot_id": [ { "id": "GLU2B_YEAST", "url": "https://www.uniprot.org/uniprot/Q04924", "type": "external" } ], "mass": 79907.0, "length": 702, "protein_name": "Glucosidase 2 subunit beta", "gene_name": "GTB1", "organism": "Yeast", "refseq_name": "Gtb1p", "refseq_ac": [ { "id": "NP_010507", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010507", "type": "external" } ], "gene_names_uniprotkb": "GTB1", "gene_names_refseq": "GTB1", "protein_names_uniprotkb": "Glucosidase 2 subunit beta; Alpha-glucosidase 2 subunit beta; Alpha-glucosidase II subunit beta; Glucosidase II subunit beta", "protein_names_refseq": "Gtb1p", "tax_id": 559292, "disease": "polycystic liver disease (Disease Ontology:DOID:0050770); polycystic liver disease 1 (Disease Ontology:DOID:0060980); liver disease (Disease Ontology:DOID:409)", "pathway": " (sce:YDR221W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;14562106;16373354;24374639;33229814;9169867", "class_list": "", "function": "Subunit of glucosidase 2, which cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Specifically required for the cleavage of the final glucose., [UniProtKB, PubMed]", "predicted_glycosites": 7, "predicted_n_glycosites": 7, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "D6VSK3", "ec_number_list": [], "go_molecular_function": "GO:0008047 enzyme activator activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen;GO:0017177 glucosidase II complex", "go_biological_process": "GO:0000271 polysaccharide biosynthetic process;GO:0006491 N-glycan processing;GO:0070880 fungal-type cell wall beta-glucan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q04924-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0100000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q05021-1", "uniprot_id": [ { "id": "TAF7_YEAST", "url": "https://www.uniprot.org/uniprot/Q05021", "type": "external" } ], "mass": 67555.0, "length": 590, "protein_name": "Transcription initiation factor TFIID subunit 7", "gene_name": "TAF7", "organism": "Yeast", "refseq_name": "TATA-binding protein-associated factor TAF7", "refseq_ac": [ { "id": "NP_013954", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013954", "type": "external" } ], "gene_names_uniprotkb": "TAF7; TAF67; YM9959.09C", "gene_names_refseq": "TAF67; TAF7", "protein_names_uniprotkb": "Transcription initiation factor TFIID subunit 7; TAFII-67; TBP-associated factor 67 kDa; TBP-associated factor 7", "protein_names_refseq": "TATA-binding protein-associated factor TAF7", "tax_id": 559292, "disease": "oligospermia (Disease Ontology:DOID:14228)", "pathway": " (sce:YMR227C); (R-SCE-674695); (R-SCE-73776); (R-SCE-73779); (R-SCE-75953); (R-SCE-76042)", "pathway_count": 6, "publication_count": 15, "publication_id_list": "10783167;10788514;12093743;12138208;12516863;14562095;14562106;18407956;19684113;19779198;23749301;24374639;33481703;33491328;9169872", "class_list": "", "function": "Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription. TAF7 is responsible for the recruitment of BDF1 to TATA element containing promoters., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W052", "ec_number_list": [], "go_molecular_function": "GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005669 transcription factor TFIID complex", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006366 transcription by RNA polymerase II;GO:0051123 RNA polymerase II preinitiation complex assembly", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q05021-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q05022-1", "uniprot_id": [ { "id": "RRP5_YEAST", "url": "https://www.uniprot.org/uniprot/Q05022", "type": "external" } ], "mass": 193134.0, "length": 1729, "protein_name": "rRNA biogenesis protein RRP5", "gene_name": "RRP5", "organism": "Yeast", "refseq_name": "Rrp5p", "refseq_ac": [ { "id": "NP_013956", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013956", "type": "external" } ], "gene_names_uniprotkb": "RRP5; FMI1; YM9959.11C", "gene_names_refseq": "RRP5", "protein_names_uniprotkb": "rRNA biogenesis protein RRP5; Ribosomal RNA-processing protein 5; U3 small nucleolar RNA-associated protein RRP5; U3 snoRNA-associated protein RRP5", "protein_names_refseq": "Rrp5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR229C); (R-SCE-6791226)", "pathway_count": 2, "publication_count": 22, "publication_id_list": "12068309;14562106;15665377;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;23749301;24374639;30516470;32597660;33481703;33491328;8896463;9169872", "class_list": "", "function": "Involved in the biogenesis of rRNA. Required for the formation of 18S and 5.8S rRNA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 31, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W054", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0030515 snoRNA binding;GO:0034513 box H/ACA snoRNA binding;GO:0034511 U3 snoRNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0030686 90S preribosome;GO:0032040 small-subunit processome", "go_biological_process": "GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364 rRNA processing;GO:0034463 90S preribosome assembly", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "Q05022-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q05166-1", "uniprot_id": [ { "id": "NUP59_YEAST", "url": "https://www.uniprot.org/uniprot/Q05166", "type": "external" } ], "mass": 58793.0, "length": 528, "protein_name": "Nucleoporin ASM4", "gene_name": "ASM4", "organism": "Yeast", "refseq_name": "FG-nucleoporin ASM4", "refseq_ac": [ { "id": "NP_010195", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010195", "type": "external" } ], "gene_names_uniprotkb": "ASM4; D2420; NUP59", "gene_names_refseq": "ASM4; NUP59", "protein_names_uniprotkb": "Nucleoporin ASM4; Nuclear pore protein NUP59", "protein_names_refseq": "FG-nucleoporin ASM4", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL088C)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "10684247;10688190;11283351;12604785;12791264;14562106;14574415;17322287;17563356;18407956;19779198;19795423;19823750;20702584;23749301;24374639;32597660;33481703;33491328;7862092;8923743;9169867;9864357", "class_list": "", "function": "Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm). May have a mitosis control function (By similarity)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRR0;E9P903;Q12456", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0003697 single-stranded DNA binding;GO:0017056 structural constituent of nuclear pore", "go_cellular_component": "GO:0044615 nuclear pore nuclear basket;GO:0005635 nuclear envelope;GO:0005643 nuclear pore;GO:0031965 nuclear membrane;GO:0044613 nuclear pore central transport channel", "go_biological_process": "GO:0006999 nuclear pore organization;GO:0006913 nucleocytoplasmic transport;GO:0051301 cell division;GO:0031990 mRNA export from nucleus in response to heat stress;GO:0006607 NLS-bearing protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "Q05166-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q05471-1", "uniprot_id": [ { "id": "SWR1_YEAST", "url": "https://www.uniprot.org/uniprot/Q05471", "type": "external" } ], "mass": 174530.0, "length": 1514, "protein_name": "Chromatin remodeling protein SWR1", "gene_name": "SWR1", "organism": "Yeast", "refseq_name": "chromatin-remodeling protein SWR1", "refseq_ac": [ { "id": "NP_010621", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010621", "type": "external" } ], "gene_names_uniprotkb": "SWR1; D9651.6", "gene_names_refseq": "SWR1", "protein_names_uniprotkb": "Chromatin remodeling protein SWR1; 3.6.4.-; Swi2/Snf2-related 1", "protein_names_refseq": "chromatin-remodeling protein SWR1", "tax_id": 559292, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888); developmental disorder of mental health (Disease Ontology:DOID:0060037); Floating-Harbor syndrome (Disease Ontology:DOID:0111358)", "pathway": " (sce:YDR334W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562095;14562106;14645854;14690591;14690608;15045029;15353583;20190278;24374639;33491328;9169867", "class_list": "", "function": "Catalytic component of the SWR1 complex that mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to incorporation of histone variant H2AZ into chromatin and transcriptional regulation of selected genes by chromatin remodeling., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VSW6", "ec_number_list": [ { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "5.6.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.4", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" } ], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0005198 structural molecule activity;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0000785 chromatin;GO:0000812 Swr1 complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006355 regulation of DNA-templated transcription;GO:0045815 transcription initiation-coupled chromatin remodeling;GO:0000725 recombinational repair", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q05471-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q05791-1", "uniprot_id": [ { "id": "CD123_YEAST", "url": "https://www.uniprot.org/uniprot/Q05791", "type": "external" } ], "mass": 41852.0, "length": 360, "protein_name": "Translation initiation factor eIF2 assembly protein", "gene_name": "CDC123", "organism": "Yeast", "refseq_name": "cell proliferation protein CDC123", "refseq_ac": [ { "id": "NP_013316", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013316", "type": "external" } ], "gene_names_uniprotkb": "CDC123", "gene_names_refseq": "CDC123", "protein_names_uniprotkb": "Translation initiation factor eIF2 assembly protein; Cell division cycle protein 123", "protein_names_refseq": "cell proliferation protein CDC123", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR215C)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "14562095;14562106;15319434;17322287;19684113;19779198;19795423;19823750;21725298;23749301;23775072;24374639;26211610;33491328;35031321;37507029;9169871", "class_list": "", "function": "ATP-dependent protein-folding chaperone for the eIF2 complex (PubMed:23775072, PubMed:26211610). Binds to the gamma subunit of the eIF2 complex which allows the subunit to assemble with the alpha and beta subunits (PubMed:23775072, PubMed:35031321)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYL6", "ec_number_list": [], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:1905143 eukaryotic translation initiation factor 2 complex assembly", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q05791-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q05924-1", "uniprot_id": [ { "id": "DCR2_YEAST", "url": "https://www.uniprot.org/uniprot/Q05924", "type": "external" } ], "mass": 66463.0, "length": 578, "protein_name": "Phosphatase DCR2", "gene_name": "DCR2", "organism": "Yeast", "refseq_name": "phosphoprotein phosphatase", "refseq_ac": [ { "id": "NP_013465", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013465", "type": "external" } ], "gene_names_uniprotkb": "DCR2", "gene_names_refseq": "DCR2", "protein_names_uniprotkb": "Phosphatase DCR2; 3.1.-.-; Dosage-dependent cell cycle regulator 2", "protein_names_refseq": "phosphoprotein phosphatase", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR361C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "14562106;15590836;24374639;9169871", "class_list": "", "function": "Required for cell cycle progression. Has a role in the completion of START., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYZ8", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016788 hydrolase activity, acting on ester bonds;GO:0004721 phosphoprotein phosphatase activity", "go_cellular_component": "GO:0000324 fungal-type vacuole", "go_biological_process": "GO:1900102 negative regulation of endoplasmic reticulum unfolded protein response;GO:0007089 traversing start control point of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q05924-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q05933-1", "uniprot_id": [ { "id": "ARPC3_YEAST", "url": "https://www.uniprot.org/uniprot/Q05933", "type": "external" } ], "mass": 20579.0, "length": 178, "protein_name": "Actin-related protein 2/3 complex subunit 3", "gene_name": "ARC18", "organism": "Yeast", "refseq_name": "Arc18p", "refseq_ac": [ { "id": "NP_013474", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013474", "type": "external" } ], "gene_names_uniprotkb": "ARC18; L8039.15", "gene_names_refseq": "ARC18", "protein_names_uniprotkb": "Actin-related protein 2/3 complex subunit 3; Arp2/3 complex 21 kDa subunit; p21-ARC", "protein_names_refseq": "Arc18p", "tax_id": 559292, "disease": "Parkinson's disease (Disease Ontology:DOID:14330); diabetes mellitus (Disease Ontology:DOID:9351)", "pathway": " (sce:YLR370C); (R-SCE-2029482); (R-SCE-5663213)", "pathway_count": 3, "publication_count": 7, "publication_id_list": "14562106;17322287;22106047;22814378;24374639;9169871;9210376", "class_list": "", "function": "Functions as a component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ07", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0015629 actin cytoskeleton;GO:0005885 Arp2/3 protein complex", "go_biological_process": "GO:0034314 Arp2/3 complex-mediated actin nucleation;GO:0045010 actin nucleation;GO:0030833 regulation of actin filament polymerization;GO:0051654 establishment of mitochondrion localization;GO:0044396 actin cortical patch organization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q05933-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q05942-1", "uniprot_id": [ { "id": "RSA3_YEAST", "url": "https://www.uniprot.org/uniprot/Q05942", "type": "external" } ], "mass": 24656.0, "length": 220, "protein_name": "Ribosome assembly protein 3", "gene_name": "RSA3", "organism": "Yeast", "refseq_name": "Rsa3p", "refseq_ac": [ { "id": "NP_013322", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013322", "type": "external" } ], "gene_names_uniprotkb": "RSA3", "gene_names_refseq": "RSA3", "protein_names_uniprotkb": "Ribosome assembly protein 3", "protein_names_refseq": "Rsa3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR221C)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "14562095;14562106;15126390;17145778;17322287;18407956;19684113;19779198;19795423;19823750;21177495;22218487;22814378;24374639;30516470;32597660;33481703;33491328;9169871", "class_list": "", "function": "Required for efficient biogenesis of the 60S ribosomal subunit., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYM1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor", "go_biological_process": "GO:0042273 ribosomal large subunit biogenesis;GO:0000027 ribosomal large subunit assembly", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q05942-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q06091-1", "uniprot_id": [ { "id": "SN309_YEAST", "url": "https://www.uniprot.org/uniprot/Q06091", "type": "external" } ], "mass": 20709.0, "length": 175, "protein_name": "Pre-mRNA-splicing factor SNT309", "gene_name": "SNT309", "organism": "Yeast", "refseq_name": "Snt309p", "refseq_ac": [ { "id": "NP_015426", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015426", "type": "external" } ], "gene_names_uniprotkb": "SNT309; NTC25", "gene_names_refseq": "NTC25; SNT309", "protein_names_uniprotkb": "Pre-mRNA-splicing factor SNT309; PRP19-associated complex protein 25; Synergistic to PRP19 mutation protein 309", "protein_names_refseq": "Snt309p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR101W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10318896;11018040;11884590;12088152;14562095;14562106;14690591;17322287;24374639;9169875;9528791", "class_list": "", "function": "Involved in pre-mRNA splicing by stabilizing the NTC (or PRP19-associated complex). As a component of the NTC complex, associates to the spliceosome to mediate conformational rearrangement or to stabilize the structure of the spliceosome after U4 snRNA dissociation, which leads to spliceosome maturation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W499", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0071006 U2-type catalytic step 1 spliceosome;GO:0000974 Prp19 complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q06091-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q06132-1", "uniprot_id": [ { "id": "SGD1_YEAST", "url": "https://www.uniprot.org/uniprot/Q06132", "type": "external" } ], "mass": 102853.0, "length": 899, "protein_name": "Suppressor of glycerol defect protein 1", "gene_name": "SGD1", "organism": "Yeast", "refseq_name": "Sgd1p", "refseq_ac": [ { "id": "NP_013440", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013440", "type": "external" } ], "gene_names_uniprotkb": "SGD1", "gene_names_refseq": "SGD1", "protein_names_uniprotkb": "Suppressor of glycerol defect protein 1", "protein_names_refseq": "Sgd1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR336C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "11042259;12073033;14562095;14562106;17287358;19684113;19779198;22814378;23749301;24374639;33481703;33491328;9169871", "class_list": "", "function": "Involved in osmoregulatory glycerol response, probably through its interaction with PLC1 which regulates the expression of GDP1., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VYX6", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0097078 FAL1-SGD1 complex", "go_biological_process": "GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0042274 ribosomal small subunit biogenesis;GO:0006972 hyperosmotic response", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q06132-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q06137-1", "uniprot_id": [ { "id": "YL345_YEAST", "url": "https://www.uniprot.org/uniprot/Q06137", "type": "external" } ], "mass": 58386.0, "length": 509, "protein_name": "Putative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase YLR345W", "gene_name": "", "organism": "Yeast", "refseq_name": "bifunctional fructose-2,6-bisphosphate 2-phosphatase/6-phosphofructo-2-kinase", "refseq_ac": [ { "id": "NP_013449", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013449", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Putative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase YLR345W", "protein_names_refseq": "bifunctional fructose-2,6-bisphosphate 2-phosphatase/6-phosphofructo-2-kinase", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR345W); (R-SCE-9634600)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "14562095;14562106;15494396;17563356;18407956;19795423;19823750;21177495;22814378;24374639;33481703;33491328;9169871", "class_list": "", "function": "Synthesis and degradation of fructose 2,6-bisphosphate., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYY4", "ec_number_list": [ { "id": "3.1.3.46", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.46", "type": "external" }, { "id": "2.7.1.105", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.105", "type": "external" } ], "go_molecular_function": "GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity;GO:0005524 ATP binding;GO:0003873 6-phosphofructo-2-kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006110 regulation of glycolytic process;GO:0006000 fructose metabolic process;GO:0006003 fructose 2,6-bisphosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q06137-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q06151-1", "uniprot_id": [ { "id": "DCPS_YEAST", "url": "https://www.uniprot.org/uniprot/Q06151", "type": "external" } ], "mass": 40770.0, "length": 350, "protein_name": "m7GpppX diphosphatase", "gene_name": "DCS1", "organism": "Yeast", "refseq_name": "5'-(N(7)-methyl 5'-triphosphoguanosine)-(mRNA) diphosphatase", "refseq_ac": [ { "id": "NP_013372", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013372", "type": "external" } ], "gene_names_uniprotkb": "DCS1", "gene_names_refseq": "DCS1", "protein_names_uniprotkb": "m7GpppX diphosphatase; 3.6.1.59; DCS-1; Hint-related 7meGMP-directed hydrolase 1; Protein Dcs1p; Scavenger mRNA-decapping enzyme DcpS", "protein_names_refseq": "5'-(N(7)-methyl 5'-triphosphoguanosine)-(mRNA) diphosphatase", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR270W); (R-SCE-429958)", "pathway_count": 2, "publication_count": 23, "publication_id_list": "12198172;14523240;14562095;14562106;15240832;15273322;15665377;16207815;16260594;16963086;17322287;17330950;18407956;19779198;21126336;22814378;22985415;23749301;24374639;32597660;33481703;33491328;9169871", "class_list": "", "function": "Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) and tri-methyl guanosine nucleoside triphosphate (m3(2,2,7)GpppG) with up to 10 nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated RNA fragments and 7-methylguanosine monophosphate (m7GMP) or tri-methyl guanosine nucleoside monophosphate (m3(2,2,7)GMP), respectively. Does not hydrolyze unmethylated cap analog (GpppG) and shows no decapping activity on intact m7GpppG-capped mRNA molecules longer than 25 nucleotides. Does not hydrolyze 7-methylguanosine diphosphate (m7GDP) and tri-methylguanosine diphosphate (m3(2,2,7)GDP) to (m(7)GMP) and m3(2,2,7)GMP, respectively (PubMed:22985415). May also play a role in the 5'->3 mRNA decay pathway; m7GDP, the downstream product released by the 5'->3' mRNA mediated decapping activity, may be also converted by DCS1 to m7GMP (PubMed:14523240). Binds to m7GpppG and strongly to m7GDP. May also regulate the 5'->3' exoribonucleolytic mRNA decay pathway in a cap-independent manner. Negatively regulates trehalase activity., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYR7;Q6Q5L1", "ec_number_list": [ { "id": "3.6.1.59", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.59", "type": "external" } ], "go_molecular_function": "GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0000340 RNA 7-methylguanosine cap binding;GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0048471 perinuclear region of cytoplasm;GO:0000932 P-body", "go_biological_process": "GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay;GO:0006970 response to osmotic stress;GO:0006979 response to oxidative stress;GO:0007584 response to nutrient", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "Q06151-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q06346-1", "uniprot_id": [ { "id": "KEI1_YEAST", "url": "https://www.uniprot.org/uniprot/Q06346", "type": "external" } ], "mass": 25484.0, "length": 221, "protein_name": "Inositol phosphorylceramide synthase regulatory subunit KEI1", "gene_name": "KEI1", "organism": "Yeast", "refseq_name": "Kei1p", "refseq_ac": [ { "id": "NP_010655", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010655", "type": "external" } ], "gene_names_uniprotkb": "KEI1", "gene_names_refseq": "KEI1", "protein_names_uniprotkb": "Inositol phosphorylceramide synthase regulatory subunit KEI1; ICP synthase regulatory subunit KEI1; KEX2-cleavable protein essential for inositol phosphorylceramide synthesis", "protein_names_refseq": "Kei1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR367W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10734188;14562095;14562106;19726565;24374639;9169867", "class_list": "", "function": "Regulatory component of the inositol phosphorylceramide (ICP) synthase which catalyzes the addition of a phosphorylinositol group onto ceramide to form inositol phosphorylceramide, an essential step in sphingolipid biosynthesis. Helps the medial Golgi localization of IPC synthase in a COPI vesicle-dependent manner., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSZ8;Q06999", "ec_number_list": [], "go_molecular_function": "GO:0070917 inositol phosphoceramide synthase regulator activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0070916 inositol phosphoceramide synthase complex", "go_biological_process": "GO:0030148 sphingolipid biosynthetic process;GO:0006673 inositol phosphoceramide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q06346-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q06525-1", "uniprot_id": [ { "id": "URN1_YEAST", "url": "https://www.uniprot.org/uniprot/Q06525", "type": "external" } ], "mass": 54139.0, "length": 465, "protein_name": "Pre-mRNA-splicing factor URN1", "gene_name": "URN1", "organism": "Yeast", "refseq_name": "Urn1p", "refseq_ac": [ { "id": "NP_015478", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015478", "type": "external" } ], "gene_names_uniprotkb": "URN1", "gene_names_refseq": "URN1", "protein_names_uniprotkb": "Pre-mRNA-splicing factor URN1; U2-U5-U6 snRNP, RES complex and NTC-interacting pre-mRNA-splicing factor 1", "protein_names_refseq": "Urn1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR152C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "14562095;14562106;16606443;17322287;18407956;18536009;19941820;21126336;21386897;23560879;24374639;33491328;9169875", "class_list": "", "function": "Component of the spliceosome involved in mRNA processing., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4E8", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0005634 nucleus;GO:0071010 prespliceosome;GO:0071004 U2-type prespliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0045292 mRNA cis splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q06525-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q06632-1", "uniprot_id": [ { "id": "CFT1_YEAST", "url": "https://www.uniprot.org/uniprot/Q06632", "type": "external" } ], "mass": 153405.0, "length": 1357, "protein_name": "Protein CFT1", "gene_name": "CFT1", "organism": "Yeast", "refseq_name": "cleavage/polyadenylation factor CFT1", "refseq_ac": [ { "id": "NP_010587", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010587", "type": "external" } ], "gene_names_uniprotkb": "CFT1; YHH1", "gene_names_refseq": "CFT1; YHH1", "protein_names_uniprotkb": "Protein CFT1; Cleavage factor two protein 1", "protein_names_refseq": "cleavage/polyadenylation factor CFT1", "tax_id": 559292, "disease": "myopia (Disease Ontology:DOID:11830)", "pathway": " (sce:YDR301W); (R-SCE-77595)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "12145212;12819204;14562095;14562106;24374639;8929410;9169867", "class_list": "", "function": "RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Involved in poly(A) site recognition. May be involved in coupling transcription termination and mRNA 3'-end formation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VST0", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005847 mRNA cleavage and polyadenylation specificity factor complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0006369 termination of RNA polymerase II transcription;GO:0030846 termination of RNA polymerase II transcription, poly(A)-coupled", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q06632-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q06648-1", "uniprot_id": [ { "id": "GIC2_YEAST", "url": "https://www.uniprot.org/uniprot/Q06648", "type": "external" } ], "mass": 42852.0, "length": 383, "protein_name": "GTPase-interacting component 2", "gene_name": "GIC2", "organism": "Yeast", "refseq_name": "Gic2p", "refseq_ac": [ { "id": "NP_010595", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010595", "type": "external" } ], "gene_names_uniprotkb": "GIC2; D9740.18", "gene_names_refseq": "GIC2", "protein_names_uniprotkb": "GTPase-interacting component 2", "protein_names_refseq": "Gic2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR309C)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "14562106;15665377;17287358;17322287;17330950;17563356;18407956;19684113;19779198;19795423;19823750;21177495;22814378;23749301;24374639;30516470;32597660;33481703;33491328;9169867;9367979;9367980", "class_list": "", "function": "Required for cell size and shape control, bud site selection, bud emergence, actin cytoskeletal organization, mitotic spindle orientation/positioning, and mating projection formation in response to mating pheromone., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 29, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VST8", "ec_number_list": [], "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0000131 incipient cellular bud site;GO:0005934 cellular bud tip", "go_biological_process": "GO:0008360 regulation of cell shape;GO:0007096 regulation of exit from mitosis;GO:0030010 establishment of cell polarity;GO:0032488 Cdc42 protein signal transduction;GO:0031106 septin ring organization", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "Q06648-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q06704-1", "uniprot_id": [ { "id": "IMH1_YEAST", "url": "https://www.uniprot.org/uniprot/Q06704", "type": "external" } ], "mass": 105225.0, "length": 911, "protein_name": "Golgin IMH1", "gene_name": "IMH1", "organism": "Yeast", "refseq_name": "Imh1p", "refseq_ac": [ { "id": "NP_013412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013412", "type": "external" } ], "gene_names_uniprotkb": "IMH1; SYS3", "gene_names_refseq": "IMH1; SYS3", "protein_names_uniprotkb": "Golgin IMH1; Integrins and myosins homology protein 1", "protein_names_refseq": "Imh1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR309C); (R-SCE-6811440)", "pathway_count": 2, "publication_count": 31, "publication_id_list": "10209120;10209125;12039763;12620188;12620189;14562095;14562106;14690591;15077113;15665377;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;21177495;23749301;24374639;27821475;30516470;32597660;33229814;33481703;33491328;34965436;8663225;9169871;9880327", "class_list": "", "function": "Involved in vesicular transport between an endosomal compartment and the Golgi apparatus., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 27, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VYV3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0005829 cytosol", "go_biological_process": "GO:0016192 vesicle-mediated transport;GO:0043001 Golgi to plasma membrane protein transport;GO:0034976 response to endoplasmic reticulum stress", "synthesized_glycan_count": 0, "hit_score": 3.6, "record_id": "Q06704-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q06708-1", "uniprot_id": [ { "id": "VAC14_YEAST", "url": "https://www.uniprot.org/uniprot/Q06708", "type": "external" } ], "mass": 99773.0, "length": 880, "protein_name": "Vacuole morphology and inheritance protein 14", "gene_name": "VAC14", "organism": "Yeast", "refseq_name": "Vac14p", "refseq_ac": [ { "id": "NP_013490", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013490", "type": "external" } ], "gene_names_uniprotkb": "VAC14; L3502.1; SVP2", "gene_names_refseq": "VAC14", "protein_names_uniprotkb": "Vacuole morphology and inheritance protein 14; Swollen vacuole phenotype 2 protein", "protein_names_refseq": "Vac14p", "tax_id": 559292, "disease": "striatonigral degeneration (Disease Ontology:DOID:4751)", "pathway": " (sce:YLR386W)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "11889142;12062051;14528018;14562095;14562106;16492811;17563356;18407956;18653468;19037259;19779198;21126336;22814378;23749301;24374639;30516470;32597660;33481703;33491328;9169871", "class_list": "", "function": "The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Regulates the synthesis of PtdIns(3,5)P2 by positive activation of FAB1 and by controlling FIG4 localization. Required for FIG4-mediated turnover of PtdIns(3,5)P2 after hyperosmotic shock. Essential for the control of trafficking of some proteins to the vacuole lumen via the multivesicular body (MVB), and for maintenance of vacuole size and acidity., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 25, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ21", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0010008 endosome membrane;GO:0070772 PAS complex;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0015031 protein transport;GO:0042327 positive regulation of phosphorylation;GO:0006661 phosphatidylinositol biosynthetic process;GO:0071474 cellular hyperosmotic response;GO:1903778 protein localization to vacuolar membrane", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q06708-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q06810-1", "uniprot_id": [ { "id": "OPY2_YEAST", "url": "https://www.uniprot.org/uniprot/Q06810", "type": "external" } ], "mass": 38901.0, "length": 360, "protein_name": "Protein OPY2", "gene_name": "OPY2", "organism": "Yeast", "refseq_name": "Opy2p", "refseq_ac": [ { "id": "NP_015400", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015400", "type": "external" } ], "gene_names_uniprotkb": "OPY2", "gene_names_refseq": "OPY2", "protein_names_uniprotkb": "Protein OPY2; Overproduction-induced pheromone-resistant protein 2", "protein_names_refseq": "Opy2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR075C)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "14562095;14562106;16543225;17322287;17330950;18407956;19779198;20932477;21126336;23749301;24374639;32597660;33481703;33491328;9169875;9383053", "class_list": "", "function": "Component of the high-osmolarity glycerol (HOG) pathway involved in mating response and osmotolerance. May act as a membrane anchor for the STE50/STE11 complex., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 17, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6W479;Q6B149", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0000329 fungal-type vacuole membrane;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0007231 osmosensory signaling pathway;GO:0072659 protein localization to plasma membrane;GO:0000751 mitotic cell cycle G1 arrest in response to pheromone;GO:1900436 positive regulation of filamentous growth of a population of unicellular organisms in response to starvation;GO:0007232 osmosensory signaling pathway via Sho1 osmosensor", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q06810-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q07442-1", "uniprot_id": [ { "id": "BDF2_YEAST", "url": "https://www.uniprot.org/uniprot/Q07442", "type": "external" } ], "mass": 72513.0, "length": 638, "protein_name": "Bromodomain-containing factor 2", "gene_name": "BDF2", "organism": "Yeast", "refseq_name": "Bdf2p", "refseq_ac": [ { "id": "NP_010213", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010213", "type": "external" } ], "gene_names_uniprotkb": "BDF2", "gene_names_refseq": "BDF2", "protein_names_uniprotkb": "Bromodomain-containing factor 2", "protein_names_refseq": "Bdf2p", "tax_id": 559292, "disease": "idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); Cornelia de Lange syndrome 6 (Disease Ontology:DOID:0060970); spermatogenic failure 21 (Disease Ontology:DOID:0070163); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); nephrocalcinosis (Disease Ontology:DOID:12679); azoospermia (Disease Ontology:DOID:14227); oligospermia (Disease Ontology:DOID:14228); melanoma (Disease Ontology:DOID:1909); colon cancer (Disease Ontology:DOID:219); transitional cell carcinoma (Disease Ontology:DOID:2671); photosensitivity disease (Disease Ontology:DOID:3159); papillary thyroid carcinoma (Disease Ontology:DOID:3969); juvenile myoclonic epilepsy (Disease Ontology:DOID:4890); B-cell lymphoma (Disease Ontology:DOID:707)", "pathway": " (sce:YDL070W)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "10783167;12620224;14562095;14562106;15143168;17330950;18407956;19779198;21126336;23749301;24374639;24909858;30516470;32597660;33481703;33491328;9169867;9175470", "class_list": "", "function": "Transcription factor involved in the expression of a broad class of genes including snRNAs. Required for sporulation and DNA-damage repair. Prevents the spreading of SIR silencing at telomeres and protects histone H4, but not H3, from deacetylation (By similarity)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 14, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRS8", "ec_number_list": [], "go_molecular_function": "GO:0042393 histone binding;GO:0001094 TFIID-class transcription factor complex binding;GO:0001046 core promoter sequence-specific DNA binding;GO:0140566 histone reader activity;GO:0140129 histone H3K56ac reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0071944 cell periphery;GO:0000785 chromatin", "go_biological_process": "GO:0006281 DNA repair;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0031452 negative regulation of heterochromatin formation;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q07442-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q07505-1", "uniprot_id": [ { "id": "DLHH_YEAST", "url": "https://www.uniprot.org/uniprot/Q07505", "type": "external" } ], "mass": 30837.0, "length": 273, "protein_name": "Putative carboxymethylenebutenolidase", "gene_name": "", "organism": "Yeast", "refseq_name": "carboxymethylenebutenolidase", "refseq_ac": [ { "id": "NP_010197", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010197", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Putative carboxymethylenebutenolidase; 3.1.1.45; DLH; Dienelactone hydrolase", "protein_names_refseq": "carboxymethylenebutenolidase", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL086W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "22814378;24374639;33491328;9169867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRR2", "ec_number_list": [ { "id": "3.1.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.45", "type": "external" } ], "go_molecular_function": "GO:0008806 carboxymethylenebutenolidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q07505-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q07657-1", "uniprot_id": [ { "id": "SHS1_YEAST", "url": "https://www.uniprot.org/uniprot/Q07657", "type": "external" } ], "mass": 62630.0, "length": 551, "protein_name": "Seventh homolog of septin 1", "gene_name": "SHS1", "organism": "Yeast", "refseq_name": "septin SHS1", "refseq_ac": [ { "id": "NP_010056", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010056", "type": "external" } ], "gene_names_uniprotkb": "SHS1; SEP7", "gene_names_refseq": "SEP7; SHS1", "protein_names_uniprotkb": "Seventh homolog of septin 1; Septation protein 7", "protein_names_refseq": "septin SHS1", "tax_id": 559292, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (sce:YDL225W)", "pathway_count": 1, "publication_count": 32, "publication_id_list": "10579719;12058072;12636916;14562095;14562106;15282341;15665377;17330950;17563356;18407956;18431499;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22144691;22218487;22814378;23749301;24374639;25971666;30516470;32597660;33481703;33491328;33502312;9169867;9790978;9813092", "class_list": "", "function": "Septins are GTPases involved in cytokinesis that assemble early in the cell cycle as a patch at the incipient bud site and form a ring approximately 15 minutes before bud emergence, which transforms into an hour-glass shaped collar of cortical filaments that spans both sides of the mother-bud neck (PubMed:9790978). This collar persists until just before cytokinesis, when it splits into two rings that occupy opposite sides of the neck (PubMed:9790978). The septins at the bud neck serve as a structural scaffold that recruits different components involved in diverse processes at specific stages during the cell cycle (PubMed:9790978). Many proteins bind asymmetrically to the septin collar (PubMed:9790978). The septin assembly is regulated by protein kinases GIN4 and/or CLA4 (PubMed:9790978). May act by recruiting MYO1 and HOF1, a protein involved in septation, to the site of cleavage (PubMed:9790978). Septins are also involved in cell morphogenesis, bud site selection, chitin deposition, cell cycle regulation, cell compartmentalization and spore wall formation (PubMed:9790978). CDCd11 with SHS1 11 are involved in the recruitment of BNI5 and thereby ensure efficient localization at the bud neck of MYO1, the type II myosin of the actomyosin contractile ring (PubMed:25971666)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 93, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRD0", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003924 GTPase activity;GO:0005200 structural constituent of cytoskeleton;GO:0005525 GTP binding", "go_cellular_component": "GO:0005940 septin ring;GO:0005829 cytosol;GO:0015630 microtubule cytoskeleton;GO:0031105 septin complex;GO:0032153 cell division site", "go_biological_process": "GO:0000920 septum digestion after cytokinesis;GO:0061163 endoplasmic reticulum polarization;GO:0000082 G1/S transition of mitotic cell cycle;GO:0010458 exit from mitosis;GO:0000921 septin ring assembly", "synthesized_glycan_count": 0, "hit_score": 3.3, "record_id": "Q07657-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q07845-1", "uniprot_id": [ { "id": "GRC3_YEAST", "url": "https://www.uniprot.org/uniprot/Q07845", "type": "external" } ], "mass": 72258.0, "length": 632, "protein_name": "Polynucleotide 5'-hydroxyl-kinase GRC3", "gene_name": "GRC3", "organism": "Yeast", "refseq_name": "polynucleotide 5'-hydroxyl-kinase", "refseq_ac": [ { "id": "NP_013065", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013065", "type": "external" } ], "gene_names_uniprotkb": "GRC3", "gene_names_refseq": "GRC3", "protein_names_uniprotkb": "Polynucleotide 5'-hydroxyl-kinase GRC3; 2.7.1.-; Protein GRC3", "protein_names_refseq": "polynucleotide 5'-hydroxyl-kinase", "tax_id": 559292, "disease": "", "pathway": " (sce:YLL035W); (R-SCE-6791226)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "10649456;12837249;19779198;20814424;24374639;33481703;33491328;9169871", "class_list": "", "function": "Polynucleotide 5'-kinase involved in rRNA processing. Required for the efficient termination by RNA polymerase I and the processing of the IST2 pre-rRNA internal transcribed spacer localized between the 5.8S and 25S rRNAs. May act by maintaining the phosphorylated status of the downstream RNT1 cleavage product, which in turn allows the torpedo activity of RAT1 to efficiently terminate Pol I transcription. In vitro, displays polynucleotide kinase activity on both single- and double-stranded RNA and on single-stranded DNA alone, but not double-stranded DNA alone., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXX0;Q9P4W6", "ec_number_list": [ { "id": "3.4.22.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.-", "type": "external" }, { "id": "3.4.22.68", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.68", "type": "external" }, { "id": "2.7.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0051731 polynucleotide 5'-hydroxyl-kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0030874 nucleolar chromatin", "go_biological_process": "GO:0006364 rRNA processing;GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006363 termination of RNA polymerase I transcription", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q07845-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q07979-1", "uniprot_id": [ { "id": "RSC58_YEAST", "url": "https://www.uniprot.org/uniprot/Q07979", "type": "external" } ], "mass": 57794.0, "length": 502, "protein_name": "Chromatin structure-remodeling complex protein RSC58", "gene_name": "RSC58", "organism": "Yeast", "refseq_name": "Rsc58p", "refseq_ac": [ { "id": "NP_013133", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013133", "type": "external" } ], "gene_names_uniprotkb": "RSC58", "gene_names_refseq": "RSC58", "protein_names_uniprotkb": "Chromatin structure-remodeling complex protein RSC58; Remodel the structure of chromatin complex subunit 58", "protein_names_refseq": "Rsc58p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR033W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10025404;10329629;10619019;12052880;12072455;12183366;12697820;14562106;23749301;24374639;33481703;33491328;8980231;9169871", "class_list": "", "function": "Component of the chromatin structure-remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY35", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0016586 RSC-type complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006368 transcription elongation by RNA polymerase II;GO:0006337 nucleosome disassembly", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q07979-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08003-1", "uniprot_id": [ { "id": "RFU1_YEAST", "url": "https://www.uniprot.org/uniprot/Q08003", "type": "external" } ], "mass": 22850.0, "length": 200, "protein_name": "Regulator of free ubiquitin chains 1", "gene_name": "RFU1", "organism": "Yeast", "refseq_name": "Rfu1p", "refseq_ac": [ { "id": "NP_013174", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013174", "type": "external" } ], "gene_names_uniprotkb": "RFU1", "gene_names_refseq": "RFU1", "protein_names_uniprotkb": "Regulator of free ubiquitin chains 1", "protein_names_refseq": "Rfu1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR073C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;14562106;17322287;19410548;24374639;9169871", "class_list": "", "function": "Inhibitor of the DOA4 deubiquitinase involved in the regulation of protein degradation by the proteasome and maintenance of a normal level of free ubiquitin., [UniProtKB, 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"https://www.ncbi.nlm.nih.gov/protein/NP_014624", "type": "external" } ], "gene_names_uniprotkb": "TLG2", "gene_names_refseq": "TLG2", "protein_names_uniprotkb": "t-SNARE affecting a late Golgi compartment protein 2; Syntaxin TLG2", "protein_names_refseq": "t-SNARE syntaxin TLG2", "tax_id": 559292, "disease": "pseudohypoparathyroidism type 1B (Disease Ontology:DOID:0080222)", "pathway": " (sce:YOL018C); (R-SCE-6811440)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "17322287;19779198;24374639;33491328;9169874;9565594;9763449;9930650", "class_list": "", "function": "t-SNARE that functions in transport from the endosome to the late Golgi and on the endocytic pathway., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, 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membrane;GO:0005829 cytosol;GO:0012505 endomembrane system;GO:0010008 endosome membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006897 endocytosis;GO:0009306 protein secretion;GO:0042147 retrograde transport, endosome to Golgi;GO:0032258 cytoplasm to vacuole targeting by the Cvt pathway", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q08144-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08208-1", "uniprot_id": [ { "id": "NOP12_YEAST", "url": "https://www.uniprot.org/uniprot/Q08208", "type": "external" } ], "mass": 51942.0, "length": 459, "protein_name": "Nucleolar protein 12", "gene_name": "NOP12", "organism": "Yeast", "refseq_name": "rRNA-processing protein NOP12", "refseq_ac": [ { "id": "NP_014601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014601", "type": "external" } ], "gene_names_uniprotkb": "NOP12", "gene_names_refseq": "NOP12", "protein_names_uniprotkb": "Nucleolar protein 12", "protein_names_refseq": "rRNA-processing protein NOP12", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL041C)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "11452019;14562095;14562106;17287358;17330950;17563356;18407956;19779198;19795423;19823750;20489023;20702584;21126336;21177495;22218487;23749301;24374639;30516470;32597660;33481703;33491328;9169874", "class_list": "", "function": "Involved in pre-25S rRNA processing., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, 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5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "Q08208-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08215-1", "uniprot_id": [ { "id": "PEX15_YEAST", "url": "https://www.uniprot.org/uniprot/Q08215", "type": "external" } ], "mass": 43676.0, "length": 383, "protein_name": "Peroxisomal membrane protein PEX15", "gene_name": "PEX15", "organism": "Yeast", "refseq_name": "Pex15p", "refseq_ac": [ { "id": "NP_014598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014598", "type": "external" } ], "gene_names_uniprotkb": "PEX15; PAS21", "gene_names_refseq": "PAS21; PEX15", "protein_names_uniprotkb": "Peroxisomal membrane protein PEX15; Peroxin-15; Peroxisome biosynthesis protein PAS21", "protein_names_refseq": "Pex15p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL044W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "12808025;14562095;14562106;16007078;16763195;23749301;24374639;24821790;33491328;9169874;9405362", "class_list": "", "function": "Peroxisomal docking factor that anchors PEX1 and PEX6 to peroxisome membranes (PubMed:12808025, PubMed:16007078, PubMed:9405362). PEX26 is therefore required for the formation of the PEX1-PEX6 AAA ATPase complex, a complex that mediates the extraction of the PEX5 receptor from peroxisomal membrane (PubMed:12808025, PubMed:9405362)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W222", "ec_number_list": [], "go_molecular_function": "GO:0043495 protein-membrane adaptor activity", "go_cellular_component": "GO:0005778 peroxisomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:1904949 ATPase complex", "go_biological_process": "GO:0043335 protein unfolding;GO:0016562 protein import into peroxisome matrix, receptor recycling", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q08215-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08217-1", "uniprot_id": [ { "id": "PSK2_YEAST", "url": "https://www.uniprot.org/uniprot/Q08217", "type": "external" } ], "mass": 124373.0, "length": 1101, "protein_name": "Serine/threonine-protein kinase PSK2", "gene_name": "PSK2", "organism": "Yeast", "refseq_name": "serine/threonine protein kinase PSK2", "refseq_ac": [ { "id": "NP_014597", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014597", "type": "external" } ], "gene_names_uniprotkb": "PSK2", "gene_names_refseq": "PSK2", "protein_names_uniprotkb": "Serine/threonine-protein kinase PSK2; 2.7.11.1; PAS kinase 2", "protein_names_refseq": "serine/threonine protein kinase PSK2", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL045W)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "11459942;12372297;14562095;14562106;17531808;17563356;18407956;19779198;20489023;21126336;22218487;23749301;24374639;30516470;32597660;33481703;33491328;9169874", "class_list": "", "function": "Serine/threonine-protein kinase involved in the control of sugar metabolism and translation. Phosphorylates UGP1, which is required for normal glycogen and beta-(1,6)-glucan synthesis. This phosphorylation shifts glucose partitioning toward cell wall glucan synthesis at the expense of glycogen synthesis. Also phosphorylates the glycogen synthase GSY2 and the translation factors CAF20, TIF11 and SRO9., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 24, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W221", "ec_number_list": [ { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.1.26.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.26.-", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.67", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:2000766 negative regulation of cytoplasmic translation;GO:0045719 negative regulation of glycogen biosynthetic process;GO:0060917 regulation of (1->6)-beta-D-glucan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q08217-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08234-1", "uniprot_id": [ { "id": "YO075_YEAST", "url": "https://www.uniprot.org/uniprot/Q08234", "type": "external" } ], "mass": 145072.0, "length": 1294, "protein_name": "Uncharacterized ABC transporter ATP-binding protein/permease YOL075C", "gene_name": "YOL074C", "organism": "Yeast", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_014567", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014567", "type": "external" } ], 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"go_molecular_function": "GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0016020 membrane;GO:0071944 cell periphery;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q08234-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08235-1", "uniprot_id": [ { "id": "BRX1_YEAST", "url": "https://www.uniprot.org/uniprot/Q08235", "type": "external" } ], "mass": 33531.0, "length": 291, "protein_name": "Ribosome biogenesis protein BRX1", "gene_name": "BRX1", "organism": "Yeast", "refseq_name": "ribosome biogenesis protein BRX1", "refseq_ac": [ { "id": "NP_014565", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014565", "type": "external" } ], "gene_names_uniprotkb": "BRX1", "gene_names_refseq": "BRX1", "protein_names_uniprotkb": "Ribosome biogenesis protein BRX1", "protein_names_refseq": "ribosome biogenesis protein BRX1", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL077C)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "11843177;14562095;14562106;18407956;19779198;19795423;19823750;20702584;24374639;30516470;32597660;33481703;33491328;9169874;9178509", "class_list": "", "function": "Required for biogenesis of the 60S ribosomal subunit., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1Z1", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0008097 5S rRNA binding;GO:0042134 rRNA primary transcript binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor", "go_biological_process": "GO:0000027 ribosomal large subunit assembly;GO:0000464 endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000465 exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q08235-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08236-1", "uniprot_id": [ { "id": "AVO1_YEAST", "url": "https://www.uniprot.org/uniprot/Q08236", "type": "external" } ], "mass": 131379.0, "length": 1176, "protein_name": "Target of rapamycin complex 2 subunit AVO1", "gene_name": "AVO1", "organism": "Yeast", "refseq_name": "Avo1p", "refseq_ac": [ { "id": "NP_014563", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014563", "type": "external" } ], "gene_names_uniprotkb": "AVO1; O1110", "gene_names_refseq": "AVO1", "protein_names_uniprotkb": "Target of rapamycin complex 2 subunit AVO1; Adheres voraciously to TOR2 protein 1; TORC2 subunit AVO1", "protein_names_refseq": "Avo1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL078W); (R-SCE-1257604); (R-SCE-389357); (R-SCE-5218920); (R-SCE-6804757); (R-SCE-9856530)", "pathway_count": 6, "publication_count": 24, "publication_id_list": "12408816;12631735;14562106;16002396;17330950;17563356;18407956;19684113;19779198;20489023;20702584;21126336;21177495;22218487;22505404;22814378;23749301;24374639;29170376;32597660;33481703;33491328;9169874;9178509", "class_list": "", "function": "Component of TORC2, which regulates cell cycle-dependent polarization of the actin-cytoskeleton and cell wall integrity. TORC2 controls polarity of the actin cytoskeleton, which is required for orienting the secretory pathway toward discrete growth sites, via the RHO1/PKC1/MAPK cell integrity pathway., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 67, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1Y9", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005774 vacuolar membrane;GO:0031932 TORC2 complex", "go_biological_process": "GO:0001558 regulation of cell growth;GO:0031929 TOR signaling;GO:0030950 establishment or maintenance of actin cytoskeleton polarity;GO:0038203 TORC2 signaling", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "Q08236-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08245-1", "uniprot_id": [ { "id": "ZEO1_YEAST", "url": "https://www.uniprot.org/uniprot/Q08245", "type": "external" } ], "mass": 12589.0, "length": 113, "protein_name": "Protein ZEO1", "gene_name": "ZEO1", "organism": "Yeast", "refseq_name": "Zeo1p", "refseq_ac": [ { "id": "NP_014532", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014532", "type": "external" } ], "gene_names_uniprotkb": "ZEO1; O0738", "gene_names_refseq": "ZEO1", "protein_names_uniprotkb": "Protein ZEO1; Zeocin resistance protein 1", "protein_names_refseq": "Zeo1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL109W)", "pathway_count": 1, "publication_count": 29, "publication_id_list": "12872131;12949174;15665377;17287358;17322287;17330950;17563356;17761666;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22106047;22218487;23749301;24374639;24909858;27821475;30516470;32597660;33481703;33491328;33502312;34965436;9169874", "class_list": "", "function": "Acts antagonistically to MID2 in signaling cell wall stress to the PKC1-MPK1 cell integrity pathway., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1V8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0031505 fungal-type cell wall organization;GO:1903138 negative regulation of cell integrity MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 3.0, "record_id": "Q08245-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08287-1", "uniprot_id": [ { "id": "NOP8_YEAST", "url": "https://www.uniprot.org/uniprot/Q08287", "type": "external" } ], "mass": 56966.0, "length": 484, "protein_name": "60S ribosome subunit biogenesis protein NOP8", "gene_name": "NOP8", "organism": "Yeast", "refseq_name": "Nop8p", "refseq_ac": [ { "id": "NP_014497", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014497", "type": "external" } ], "gene_names_uniprotkb": "NOP8", "gene_names_refseq": "NOP8", "protein_names_uniprotkb": "60S ribosome subunit biogenesis protein NOP8; Nucleolar protein 8", "protein_names_refseq": "Nop8p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL144W)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "14562106;17145778;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;22218487;22814378;23749301;24374639;30516470;32597660;33481703;33491328;34965436;9169874;9891085", "class_list": "", "function": "Required for 60S ribosomal subunit synthesis. May be involved in assembly reactions occurring within late pre-ribosomal particles., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1S5", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0008428 ribonuclease inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus", "go_biological_process": "GO:0042273 ribosomal large subunit biogenesis;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "Q08287-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08412-1", "uniprot_id": [ { "id": "CUE5_YEAST", "url": "https://www.uniprot.org/uniprot/Q08412", "type": "external" } ], "mass": 46870.0, "length": 411, "protein_name": "Ubiquitin-binding protein CUE5", "gene_name": "CUE5", "organism": "Yeast", "refseq_name": "ubiquitin-binding protein CUE5", "refseq_ac": [ { "id": "NP_014685", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014685", "type": "external" } ], "gene_names_uniprotkb": "CUE5", "gene_names_refseq": "CUE5", "protein_names_uniprotkb": "Ubiquitin-binding protein CUE5; Coupling of ubiquitin conjugation to ER degradation protein 5", "protein_names_refseq": "ubiquitin-binding protein CUE5", "tax_id": 559292, "disease": "neurodegenerative disease (Disease Ontology:DOID:1289)", "pathway": " (sce:YOR042W); (R-SCE-6798695)", "pathway_count": 2, "publication_count": 30, "publication_id_list": "11875433;12628920;12872131;14562095;14562106;15200949;17287358;17322287;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22106047;22218487;23749301;24374639;24909858;25042851;30516470;32597660;33481703;33491328;34965436;9169874", "class_list": "", "function": "Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 adapter and thus mediating autophagic clearance of ubiquitin conjugates under starvation conditions. The CUE5-dependent selective autophagy pathway plays an important role in clearance of cytotoxic protein aggregates. Not required for cytoplasmic to vacuole pathway (cvt), mitophagy, pexophagy, or ribophagy., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 40, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2A8", "ec_number_list": [], "go_molecular_function": "GO:0036435 K48-linked polyubiquitin modification-dependent protein binding;GO:0030674 protein-macromolecule adaptor activity;GO:0031624 ubiquitin conjugating enzyme binding;GO:0043130 ubiquitin binding;GO:0070530 K63-linked polyubiquitin modification-dependent protein binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006914 autophagy;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0006995 cellular response to nitrogen starvation", "synthesized_glycan_count": 0, "hit_score": 3.1, "record_id": "Q08412-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08465-1", "uniprot_id": [ { "id": "YNG1_YEAST", "url": "https://www.uniprot.org/uniprot/Q08465", "type": "external" } ], "mass": 25350.0, "length": 219, "protein_name": "Protein YNG1", "gene_name": "YNG1", "organism": "Yeast", "refseq_name": "Yng1p", "refseq_ac": [ { "id": "NP_014707", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014707", "type": "external" } ], "gene_names_uniprotkb": "YNG1; YOR29-15", "gene_names_refseq": "YNG1; YOR29-15", "protein_names_uniprotkb": "Protein YNG1; ING1 homolog 1", "protein_names_refseq": "Yng1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR064C)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "12077334;14562095;14562106;16728974;17157260;17322287;19779198;24374639;25104842;28108585;33481703;33491328;9133743;9169874", "class_list": "", "function": "Histone-binding component of the NuA3a histone acetyltransferase complex. Targets the NuA3a HAT complex via histone H3K4me3 to facilitate transcription initiation at promoter regions. SAS3 then acetylates H3K14, leading to transcription initiation at a subset of genes. YNG1 is required for the HAT activity of NuA3 but not for its integrity. Mediates the interaction of SAS3 with nucleosomes., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2C7;O00025", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0140002 histone H3K4me3 reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:1990467 NuA3a histone acetyltransferase complex;GO:0033100 NuA3 histone acetyltransferase complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006325 chromatin organization;GO:0032968 positive regulation of transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q08465-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08550-1", "uniprot_id": [ { "id": "MPC54_YEAST", "url": "https://www.uniprot.org/uniprot/Q08550", "type": "external" } ], "mass": 54358.0, "length": 464, "protein_name": "Meiotic plaque component protein 54", "gene_name": "MPC54", "organism": "Yeast", "refseq_name": "Mpc54p", "refseq_ac": [ { "id": "NP_014820", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014820", "type": "external" } ], "gene_names_uniprotkb": "MPC54", "gene_names_refseq": "MPC54", "protein_names_uniprotkb": "Meiotic plaque component protein 54", "protein_names_refseq": "Mpc54p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR177C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10899120;11553705;11742972;12796288;24374639;33491328;9169874", "class_list": "", "function": "Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2N3", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005816 spindle pole body;GO:0005628 prospore membrane;GO:0035974 meiotic spindle pole body", "go_biological_process": "GO:0051301 cell division;GO:0048278 vesicle docking;GO:0032120 ascospore-type prospore membrane formation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q08550-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08746-1", "uniprot_id": [ { "id": "RRS1_YEAST", "url": "https://www.uniprot.org/uniprot/Q08746", "type": "external" } ], "mass": 22963.0, "length": 203, "protein_name": "Regulator of ribosome biosynthesis", "gene_name": "RRS1", "organism": "Yeast", "refseq_name": "ribosome biogenesis protein RRS1", "refseq_ac": [ { "id": "NP_014937", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014937", "type": "external" } ], "gene_names_uniprotkb": "RRS1", "gene_names_refseq": "RRS1", "protein_names_uniprotkb": "Regulator of ribosome biosynthesis", "protein_names_refseq": "ribosome biogenesis protein RRS1", "tax_id": 559292, "disease": "Huntington's disease (Disease Ontology:DOID:12858); papillary thyroid carcinoma (Disease Ontology:DOID:3969)", "pathway": " (sce:YOR294W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10688653;24374639;33481703;33491328;37291423;9153758;9169874", "class_list": "", "function": "Required for ribosome biogenesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2Z3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor;GO:0034399 nuclear periphery", "go_biological_process": "GO:0000055 ribosomal large subunit export from nucleus;GO:0042273 ribosomal large subunit biogenesis;GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q08746-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08912-1", "uniprot_id": [ { "id": "YO389_YEAST", "url": "https://www.uniprot.org/uniprot/Q08912", "type": "external" } ], "mass": 70221.0, "length": 624, "protein_name": "Uncharacterized protein YOR389W", "gene_name": "", "organism": "Yeast", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_015034", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015034", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein YOR389W", "protein_names_refseq": "uncharacterized protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR389W)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "24374639;9169874", "class_list": "", "function": "", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D6W382", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q08912-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08920-1", "uniprot_id": [ { "id": "NCBP2_YEAST", "url": "https://www.uniprot.org/uniprot/Q08920", "type": "external" } ], "mass": 23774.0, "length": 208, "protein_name": "Nuclear cap-binding protein subunit 2", "gene_name": "CBC2", "organism": "Yeast", "refseq_name": "nuclear cap-binding protein subunit CBC2", "refseq_ac": [ { "id": "NP_015147", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015147", "type": "external" } ], "gene_names_uniprotkb": "CBC2; CBP20; MUD13; SAE1", "gene_names_refseq": "CBC2; CBP20; MUD13; SAE1", "protein_names_uniprotkb": "Nuclear cap-binding protein subunit 2; 20 kDa nuclear cap-binding protein; CBP20; NCBP 20 kDa subunit", "protein_names_refseq": "nuclear cap-binding protein subunit CBC2", "tax_id": 559292, "disease": "chromosome 3q29 microdeletion syndrome (Disease Ontology:DOID:0060419)", "pathway": " (sce:YPL178W); (R-SCE-113418); (R-SCE-674695); (R-SCE-72086); (R-SCE-72203); (R-SCE-77595); (R-SCE-975956); (R-SCE-975957)", "pathway_count": 8, "publication_count": 22, "publication_id_list": "10490594;10504710;10823828;12756324;14562095;14562106;14671320;15753296;16166263;16427013;16729021;17322287;22814378;24374639;32597660;33481703;33491328;8682299;8811086;8858145;9169875;9215889", "class_list": "", "function": "Component of the CBC complex, which binds co-transcriptionally to the cap of pre-mRNAs and is involved in maturation, export and degradation of nuclear mRNAs. The CBC complex is required for efficient pre-mRNA splicing through efficient commitment complex and spliceosome formation. Together with NPL3, the CBC complex is required for export of mRNAs out of the nucleus. The CBC complex is also involved in nuclear mRNA degradation, probably by directing the mRNAs to the sites of degradation. Affects replication of the positive-strand RNA virus BMV., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3J0", "ec_number_list": [], "go_molecular_function": "GO:0000339 RNA cap binding", "go_cellular_component": "GO:0005634 nucleus;GO:0048471 perinuclear region of cytoplasm;GO:0000243 commitment complex;GO:0005846 nuclear cap binding complex", "go_biological_process": "GO:0006406 mRNA export from nucleus;GO:0006970 response to osmotic stress;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000956 nuclear-transcribed mRNA catabolic process;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "Q08920-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08951-1", "uniprot_id": [ { "id": "AP3D_YEAST", "url": "https://www.uniprot.org/uniprot/Q08951", "type": "external" } ], "mass": 106924.0, "length": 932, "protein_name": "AP-3 complex subunit delta", "gene_name": "APL5", "organism": "Yeast", "refseq_name": "Apl5p", "refseq_ac": [ { "id": "NP_015129", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015129", "type": "external" } ], "gene_names_uniprotkb": "APL5; YKS4", "gene_names_refseq": "APL5; YKS4", "protein_names_uniprotkb": "AP-3 complex subunit delta; Adaptor-related protein complex 3 subunit delta; Delta-adaptin 3; Delta-adaptin", "protein_names_refseq": "Apl5p", "tax_id": 559292, "disease": "Hermansky-Pudlak syndrome 1 (Disease Ontology:DOID:0060539); Hermansky-Pudlak syndrome 2 (Disease Ontology:DOID:0060540); platelet storage pool deficiency (Disease Ontology:DOID:2223); Hermansky-Pudlak syndrome (Disease Ontology:DOID:3753)", "pathway": " (sce:YPL195W)", "pathway_count": 1, "publication_count": 26, "publication_id_list": "10559961;11160821;14562095;14562106;15665377;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;22218487;22814378;23749301;24374639;24909858;30516470;32597660;33229814;33481703;33491328;9169875;9250663;9335339", "class_list": "", "function": "Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole. Required for the transport via the ALP pathway, which directs the transport of the cargo proteins PHO8 and VAM3 to the vacuole., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 22, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W3H3;Q02737;Q7LIB1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0010008 endosome membrane;GO:0030665 clathrin-coated vesicle membrane;GO:0030123 AP-3 adaptor complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006623 protein targeting to vacuole;GO:0006896 Golgi to vacuole transport", "synthesized_glycan_count": 0, "hit_score": 3.0, "record_id": "Q08951-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08968-1", "uniprot_id": [ { "id": "SELO_YEAST", "url": "https://www.uniprot.org/uniprot/Q08968", "type": "external" } ], "mass": 78313.0, "length": 688, "protein_name": "Protein adenylyltransferase SelO, mitochondrial", "gene_name": "FMP40", "organism": "Yeast", "refseq_name": "Fmp40p", "refseq_ac": [ { "id": "NP_015102", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015102", "type": "external" } ], "gene_names_uniprotkb": "FMP40", "gene_names_refseq": "FMP40", "protein_names_uniprotkb": "Protein adenylyltransferase SelO, mitochondrial; 2.7.7.-; SelO; Selenoprotein O", "protein_names_refseq": "Fmp40p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL222W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;14576278;17938904;24374639;30270044;9169875", "class_list": "", "function": "Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Tyr residues of target mitochondrial proteins (AMPylation) (PubMed:30270044). Involved in redox homeostasis by regulating the cellular response to oxidative stress (PubMed:30270044). Regulates protein S-glutathionylation levels possibly by AMPylation of deglutathionylation enzymes such as glutaredoxins (PubMed:30270044)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3E8", "ec_number_list": [ { "id": "2.7.7.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0070733 AMPylase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0045454 cell redox homeostasis;GO:0018117 protein adenylylation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q08968-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12028-1", "uniprot_id": [ { "id": "AP1G1_YEAST", "url": "https://www.uniprot.org/uniprot/Q12028", "type": "external" } ], "mass": 93624.0, "length": 832, "protein_name": "AP-1 complex subunit gamma-1", "gene_name": "APL4", "organism": "Yeast", "refseq_name": "AP-1 complex subunit gamma", "refseq_ac": [ { "id": "NP_015354", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015354", "type": "external" } ], "gene_names_uniprotkb": "APL4", "gene_names_refseq": "APL4", "protein_names_uniprotkb": "AP-1 complex subunit gamma-1; Clathrin assembly protein complex 1 gamma large chain; Clathrin assembly protein large gamma chain; Gamma-adaptin", "protein_names_refseq": "AP-1 complex subunit gamma", "tax_id": 559292, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (sce:YPR029C); (R-SCE-432720)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "10564262;14562106;17563356;21126336;23749301;24374639;26658609;33491328;9169875", "class_list": "", "function": "Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles (PubMed:10564262). Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (PubMed:10564262). The AP-1 complex interacts directly with clathrin (PubMed:10564262). Component of the AP-1-related (AP-1R) complex, an adapter protein complex that mediates sorting of cargo SNARE SNC1 (PubMed:26658609). In contrast to the APM1-containing AP-1 complex, AP-1R is incapable of sorting CHS3 (PubMed:26658609)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W439", "ec_number_list": [], "go_molecular_function": "GO:0030276 clathrin binding;GO:0035615 clathrin adaptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005829 cytosol;GO:0030121 AP-1 adaptor complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0048203 vesicle targeting, trans-Golgi to endosome;GO:0006896 Golgi to vacuole transport", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q12028-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12033-1", "uniprot_id": [ { "id": "PALA_YEAST", "url": "https://www.uniprot.org/uniprot/Q12033", "type": "external" } ], "mass": 75947.0, "length": 661, "protein_name": "pH-response regulator protein palA/RIM20", "gene_name": "RIM20", "organism": "Yeast", "refseq_name": "Rim20p", "refseq_ac": [ { "id": "NP_014918", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014918", "type": "external" } ], "gene_names_uniprotkb": "RIM20", "gene_names_refseq": "RIM20", "protein_names_uniprotkb": "pH-response regulator protein palA/RIM20; Regulator of IME2 protein 20", "protein_names_refseq": "Rim20p", "tax_id": 559292, "disease": "primary autosomal recessive microcephaly 29 (Disease Ontology:DOID:0051040)", "pathway": " (sce:YOR275C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11698381;14562095;14562106;15371534;22814378;24374639;8896271;9169874", "class_list": "", "function": "Required for the proteolytic cleavage of the transcriptional repressor RIM101 in response to alkaline ambient pH, which is necessary for sporulation and invasive growth. May act as a scaffold protein that recruits the calpain-like protease RIM13 via SNF7 to its substrate RIM101., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2X5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005777 peroxisome", "go_biological_process": "GO:0016485 protein processing;GO:0001403 invasive growth in response to glucose limitation;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12033-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12046-1", "uniprot_id": [ { "id": "CWC2_YEAST", "url": "https://www.uniprot.org/uniprot/Q12046", "type": "external" } ], "mass": 38431.0, "length": 339, "protein_name": "Pre-mRNA-splicing factor CWC2", "gene_name": "CWC2", "organism": "Yeast", "refseq_name": "active spliceosome conformation promoter CWC2", "refseq_ac": [ { "id": "NP_010072", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010072", "type": "external" } ], "gene_names_uniprotkb": "CWC2; D1041; NTC40; SLC3", "gene_names_refseq": "CWC2; NTC40", "protein_names_uniprotkb": "Pre-mRNA-splicing factor CWC2; Complexed with CEF1 protein 2; PRP19-associated complex protein 40; Synthetic lethal with CLF1 protein 3", "protein_names_refseq": "active spliceosome conformation promoter CWC2", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL209C)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "11884590;12088152;12871902;14562095;14562106;14690591;17322287;19435883;19684113;19779198;19795423;19823750;22246180;23749301;24374639;33481703;33491328;9046097;9169867;9528791", "class_list": "", "function": "Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Binds also to U1, U4, U5 and U6 snRNAs and to pre-mRNAs, in vitro. Is not required for the Prp2-mediated remodeling of the activated spliceosome., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRE5", "ec_number_list": [], "go_molecular_function": "GO:0036002 pre-mRNA binding;GO:0008270 zinc ion binding;GO:0017070 U6 snRNA binding", "go_cellular_component": "GO:0071006 U2-type catalytic step 1 spliceosome;GO:0071007 U2-type catalytic step 2 spliceosome;GO:0000974 Prp19 complex", "go_biological_process": "GO:0033120 positive regulation of RNA splicing;GO:0045787 positive regulation of cell cycle;GO:0000387 spliceosomal snRNP assembly;GO:0000398 mRNA splicing, via spliceosome;GO:0045292 mRNA cis splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q12046-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12071-1", "uniprot_id": [ { "id": "VPS54_YEAST", "url": "https://www.uniprot.org/uniprot/Q12071", "type": "external" } ], "mass": 101520.0, "length": 889, "protein_name": "Vacuolar protein sorting-associated protein 54", "gene_name": "VPS54", "organism": "Yeast", "refseq_name": "Vps54p", "refseq_ac": [ { "id": "NP_010310", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010310", "type": "external" } ], "gene_names_uniprotkb": "VPS54; CGP1; LUV1; PZF889; RKI1; TCS3; YD9813.05C", "gene_names_refseq": "CGP1; LUV1; TCS3; VPS54", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 54; CPF1 genetically-interacting protein 1; Temperature-sensitive clathrin synthetic mutation protein 3", "protein_names_refseq": "Vps54p", "tax_id": 559292, "disease": "amyotrophic lateral sclerosis type 1 (Disease Ontology:DOID:0060193); Werdnig-Hoffmann disease (Disease Ontology:DOID:13137); motor neuron disease (Disease Ontology:DOID:231)", "pathway": " (sce:YDR027C)", "pathway_count": 1, "publication_count": 27, "publication_id_list": "10628971;10637310;10888679;11689439;12377769;12395193;12446664;12620189;12686613;14562095;14562106;14576278;15665377;17330950;17563356;18407956;19779198;20702584;23749301;24374639;32597660;33481703;33491328;34965436;8896275;9169867;9914379", "class_list": "", "function": "Involved in retrograde transport from early and late endosomes to late Golgi by linking the vesicle through the t-SNARE TGL1 to the Golgi, leading to the membrane fusion between late Golgi and endosomal vesicles. Also seems to be involved in protein transport from Golgi to the plasma membrane and is required for the integrity of the actin cytoskeleton., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS12", "ec_number_list": [], "go_molecular_function": "GO:0019905 syntaxin binding", "go_cellular_component": "GO:0000938 GARP complex;GO:0005739 mitochondrion;GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0042147 retrograde transport, endosome to Golgi;GO:0090156 intracellular sphingolipid homeostasis;GO:0006623 protein targeting to vacuole;GO:0006896 Golgi to vacuole transport;GO:0030476 ascospore wall assembly", "synthesized_glycan_count": 0, "hit_score": 2.8, "record_id": "Q12071-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12072-1", "uniprot_id": [ { "id": "IOC2_YEAST", "url": "https://www.uniprot.org/uniprot/Q12072", "type": "external" } ], "mass": 93446.0, "length": 812, "protein_name": "ISWI one complex protein 2", "gene_name": "IOC2", "organism": "Yeast", "refseq_name": "Ioc2p", "refseq_ac": [ { "id": "NP_013196", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013196", "type": "external" } ], "gene_names_uniprotkb": "IOC2", "gene_names_refseq": "IOC2", "protein_names_uniprotkb": "ISWI one complex protein 2", "protein_names_refseq": "Ioc2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR095C)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "12482963;14562095;14562106;14622597;18407956;19779198;20190278;21126336;23749301;24374639;32597660;33481703;33491328;9169871", "class_list": "", "function": "Functions as a component of the ISW1B complex, which acts in remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. The ISW1B complex acts within coding regions to control the amount of RNA polymerase II released into productive elongation and to coordinate elongation with termination and pre-mRNA processing., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 21, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY95", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0036437 Isw1b complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0009408 response to heat", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q12072-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12158-1", "uniprot_id": [ { "id": "SCC1_YEAST", "url": "https://www.uniprot.org/uniprot/Q12158", "type": "external" } ], "mass": 63290.0, "length": 566, "protein_name": "Sister chromatid cohesion protein 1", "gene_name": "MCD1", "organism": "Yeast", "refseq_name": "kleisin alpha", "refseq_ac": [ { "id": "NP_010281", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010281", "type": "external" } ], "gene_names_uniprotkb": "MCD1; PDS3; RHC21; SCC1; YD8119.04", "gene_names_refseq": "MCD1; PDS3; RHC21; SCC1", "protein_names_uniprotkb": "Sister chromatid cohesion protein 1", "protein_names_refseq": "kleisin alpha", "tax_id": 559292, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); colorectal carcinoma (Disease Ontology:DOID:0080199); Cornelia de Lange syndrome 4 (Disease Ontology:DOID:0080508); Cornelia de Lange syndrome (Disease Ontology:DOID:11725); brain cancer (Disease Ontology:DOID:1319); endometrial cancer (Disease Ontology:DOID:1380); congenital heart disease (Disease Ontology:DOID:1682); lung non-small cell carcinoma (Disease Ontology:DOID:3908); Roberts syndrome (Disease Ontology:DOID:5325); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (sce:YDL003W); (R-SCE-2468052); (R-SCE-2500257); (R-SCE-3108214)", "pathway_count": 4, "publication_count": 25, "publication_id_list": "10403247;11371343;11864574;11983169;14562106;15241476;17563356;18407956;18614046;19779198;20190278;20489023;20702584;23749301;24374639;27325700;30516470;32597660;33481703;33491328;9169867;9335333;9335334;9491073;9990856", "class_list": "", "function": "Cleavable component of the cohesin complex involved in chromosome cohesion during cell cycle. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by ESP1 and dissociates from chromatin, allowing sister chromatids to segregate., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 35, "reported_mutagensis": 10, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VRY5;Q05325", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0030892 mitotic cohesin complex;GO:0000794 condensed nuclear chromosome;GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0000775 chromosome, centromeric region", "go_biological_process": "GO:0051301 cell division;GO:0000086 G2/M transition of mitotic cell cycle;GO:0006915 apoptotic process;GO:0006974 DNA damage response;GO:0006302 double-strand break repair", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "Q12158-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12164-1", "uniprot_id": [ { "id": "POM33_YEAST", "url": "https://www.uniprot.org/uniprot/Q12164", "type": "external" } ], "mass": 32186.0, "length": 279, "protein_name": "Pore membrane protein of 33 kDa", "gene_name": "POM33", "organism": "Yeast", "refseq_name": "nucleoporin POM33", "refseq_ac": [ { "id": "NP_013077", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013077", "type": "external" } ], "gene_names_uniprotkb": "POM33; L1201", "gene_names_refseq": "POM33", "protein_names_uniprotkb": "Pore membrane protein of 33 kDa", "protein_names_refseq": "nucleoporin POM33", "tax_id": 559292, "disease": "", "pathway": " (sce:YLL023C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;16847258;19779198;20498018;24374639;9046100;9169871", "class_list": "", "function": "Contributes to proper distribution and/or efficient assembly of nuclear pores. Required for normal pore density in the daughter nucleus during telophase., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXY1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005643 nuclear pore;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0005640 nuclear outer membrane", "go_biological_process": "GO:0006999 nuclear pore organization;GO:0071786 endoplasmic reticulum tubular network organization;GO:0015031 protein transport;GO:0061024 membrane organization;GO:0051028 mRNA transport", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12164-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12168-1", "uniprot_id": [ { "id": "ENG2_YEAST", "url": "https://www.uniprot.org/uniprot/Q12168", "type": "external" } ], "mass": 88403.0, "length": 779, "protein_name": "Glucan endo-1,3-beta-D-glucosidase 2", "gene_name": "ACF2", "organism": "Yeast", "refseq_name": "endo-1,3(4)-beta-glucanase", "refseq_ac": [ { "id": "NP_013245", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013245", "type": "external" } ], "gene_names_uniprotkb": "ACF2; ENG2; L3180; PCA1", "gene_names_refseq": "ACF2; ENG2; PCA1", "protein_names_uniprotkb": "Glucan endo-1,3-beta-D-glucosidase 2; 3.2.1.39; Endo-1,3-beta-glucanase 2; Laminarinase-2", "protein_names_refseq": "endo-1,3(4)-beta-glucanase", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR144C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12455695;14562106;17933563;23749301;24374639;33481703;33491328;9169871", "class_list": "glycogene;glycosylhydrolase", "function": "Cleaves internal linkages in 1,3-beta-glucan., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYD8;Q07268", "ec_number_list": [], "go_molecular_function": "GO:0042973 glucan endo-1,3-beta-D-glucosidase activity;GO:0052861 endo-1,3(4)-beta-glucanase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0009986 cell surface", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0000272 polysaccharide catabolic process;GO:0071555 cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12168-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.10100", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12176-1", "uniprot_id": [ { "id": "MAK21_YEAST", "url": "https://www.uniprot.org/uniprot/Q12176", "type": "external" } ], "mass": 116677.0, "length": 1025, "protein_name": "Ribosome biogenesis protein MAK21", "gene_name": "MAK21", "organism": "Yeast", "refseq_name": "RNA-binding ribosome biosynthesis protein MAK21", "refseq_ac": [ { "id": "NP_010345", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010345", "type": "external" } ], "gene_names_uniprotkb": "MAK21; D4237; NOC1; YD9609.14", "gene_names_refseq": "MAK21; NOC1", "protein_names_uniprotkb": "Ribosome biogenesis protein MAK21; Maintenance of killer protein 21; Nucleolar complex protein 1", "protein_names_refseq": "RNA-binding ribosome biosynthesis protein MAK21", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR060W)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "11371346;14562106;15665377;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22218487;22814378;23749301;24374639;30516470;33481703;33491328;8789263;9169867;9786894", "class_list": "", "function": "Required for 60S ribosomal subunit synthesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 31, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS46", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor;GO:0030690 Noc1p-Noc2p complex", "go_biological_process": "GO:0042273 ribosomal large subunit biogenesis;GO:0000027 ribosomal large subunit assembly", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "Q12176-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12181-1", "uniprot_id": [ { "id": "NDOR1_YEAST", "url": "https://www.uniprot.org/uniprot/Q12181", "type": "external" } ], "mass": 72328.0, "length": 623, "protein_name": "NADPH-dependent diflavin oxidoreductase 1", "gene_name": "TAH18", "organism": "Yeast", "refseq_name": "NAPDH-dependent diflavin reductase", "refseq_ac": [ { "id": "NP_015373", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015373", "type": "external" } ], "gene_names_uniprotkb": "TAH18; YP9499.06", "gene_names_refseq": "TAH18", "protein_names_uniprotkb": "NADPH-dependent diflavin oxidoreductase 1; 1.18.1.-; NADPH-dependent FMN and FAD-containing oxidoreductase", "protein_names_refseq": "NAPDH-dependent diflavin reductase", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR048W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12759774;19194512;20802492;21902732;24374639;33481703;33491328;9169875", "class_list": "", "function": "NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery (PubMed:20802492). Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery (PubMed:20802492, PubMed:21902732). In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins (PubMed:20802492). Positively controls H(2)O(2)-induced cell death (PubMed:19194512)., [UniProtKB, HAMAP, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W456", "ec_number_list": [ { "id": "7.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.-.-.-", "type": "external" }, { "id": "1.18.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.18.1.-", "type": "external" } ], "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0016491 oxidoreductase activity;GO:0016651 oxidoreductase activity, acting on NAD(P)H;GO:0010181 FMN binding;GO:0050661 NADP binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0045429 positive regulation of nitric oxide biosynthetic process;GO:0034599 cellular response to oxidative stress;GO:0006809 nitric oxide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12181-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12186-1", "uniprot_id": [ { "id": "BBP_YEAST", "url": "https://www.uniprot.org/uniprot/Q12186", "type": "external" } ], "mass": 53034.0, "length": 476, "protein_name": "Branchpoint-bridging protein", "gene_name": "MSL5", "organism": "Yeast", "refseq_name": "mRNA splicing protein MSL5", "refseq_ac": [ { "id": "NP_013217", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013217", "type": "external" } ], "gene_names_uniprotkb": "MSL5; BBP; L2949; SF1", "gene_names_refseq": "MSL5", "protein_names_uniprotkb": "Branchpoint-bridging protein; Mud synthetic-lethal 5 protein; Splicing factor 1; Zinc finger protein BBP", "protein_names_refseq": "mRNA splicing protein MSL5", "tax_id": 559292, "disease": "ischemia (Disease Ontology:DOID:326)", "pathway": " (sce:YLR116W)", "pathway_count": 1, "publication_count": 27, "publication_id_list": "10376880;10775271;11875433;14562095;14562106;16120600;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;23749301;23754852;24374639;30516470;32597660;33229814;33481703;33491328;34965436;9090053;9150140;9169871", "class_list": "", "function": "Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. 2 commitment complexes, CC1 and CC2, have been defined. CC1 is a basal complex dependent only on the 5'-splice site. CC2 is a complex of lower mobility and is dependent on a branchpoint as well as a 5'-splice site region. This protein is involved in CC2 formation where it binds to the snRNP U1-associated protein PRP40, bridging the U1 snRNP-associated 5'-splice site and the MSL5-associated branch point 3' intron splice site. Involved in nuclear retention of pre-mRNA., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 13, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6VYB4", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0008270 zinc ion binding;GO:0045131 pre-mRNA branch point binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0000243 commitment complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0000245 spliceosomal complex assembly;GO:0045292 mRNA cis splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 3.2, "record_id": "Q12186-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12200-1", "uniprot_id": [ { "id": "NPC1_YEAST", "url": "https://www.uniprot.org/uniprot/Q12200", "type": "external" } ], "mass": 132645.0, "length": 1170, "protein_name": "NPC intracellular sterol transporter 1-related protein 1", "gene_name": "NCR1", "organism": "Yeast", "refseq_name": "sphingolipid transporter", "refseq_ac": [ { "id": "NP_015319", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015319", "type": "external" } ], "gene_names_uniprotkb": "NCR1", "gene_names_refseq": "NCR1", "protein_names_uniprotkb": "NPC intracellular sterol transporter 1-related protein 1; Niemann-Pick type C-related protein 1", "protein_names_refseq": "sphingolipid transporter", "tax_id": 559292, "disease": "Niemann-Pick disease type C1 (Disease Ontology:DOID:0070113); Niemann-Pick disease (Disease Ontology:DOID:14504)", "pathway": " (sce:YPL006W); (R-SCE-8963678); (R-SCE-8964038)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "14562095;14562106;14970192;15522102;16138904;24374639;33491328;9169875", "class_list": "", "function": "Involved in sphingolipid trafficking. May recycle sphingolipids between cellular membranous compartments., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 2, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 2, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 2, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D6W406", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0032934 sterol binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0006665 sphingolipid metabolic process;GO:0015918 sterol transport", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q12200-1", "record_type": "protein", "filter_code": "0000000.0100111.010000.000000000000000010.1000000010001.101.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12208-1", "uniprot_id": [ { "id": "USB1_YEAST", "url": "https://www.uniprot.org/uniprot/Q12208", "type": "external" } ], "mass": 33694.0, "length": 290, "protein_name": "U6 snRNA phosphodiesterase 1", "gene_name": "USB1", "organism": "Yeast", "refseq_name": "phosphoric diester hydrolase", "refseq_ac": [ { "id": "NP_013233", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013233", "type": "external" } ], "gene_names_uniprotkb": "USB1; L3127", "gene_names_refseq": "USB1", "protein_names_uniprotkb": "U6 snRNA phosphodiesterase 1; 3'-5' RNA exonuclease USB1; 3.1.4.-; 4.6.1.-; Cyclic phosphodiesterase USB1; U six biogenesis protein 1", "protein_names_refseq": "phosphoric diester hydrolase", "tax_id": 559292, "disease": "ablepharon macrostomia syndrome (Disease Ontology:DOID:0060550); poikiloderma with neutropenia (Disease Ontology:DOID:0060551)", "pathway": " (sce:YLR132C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562095;14562106;14690591;18407956;22899009;23190533;24374639;28887445;33481703;33491328;9169871", "class_list": "", "function": "3'-5' RNA exonuclease that trims the 3' end of oligo(U) tracts of the pre-U6 small nuclear RNA (snRNA) molecule, leading to the formation of a U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate (PubMed:28887445). In a second step acts as a cyclic phosphodiesterase that hydrolyzes a U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate to a U6 snRNA 3'-end-terminated with a 3' phosphate (PubMed:22899009, PubMed:28887445). Participates in the U6 snRNA 3' end processing that prevents U6 snRNA degradation (PubMed:22899009, PubMed:23190533, PubMed:28887445). Could be involved in aerobic respiration (PubMed:14690591)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VYC7", "ec_number_list": [ { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "4.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0016829 lyase activity;GO:0000175 3'-5'-RNA exonuclease activity;GO:1990838 poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends;GO:0008663 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0034477 U6 snRNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q12208-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12245-1", "uniprot_id": [ { "id": "POC4_YEAST", "url": "https://www.uniprot.org/uniprot/Q12245", "type": "external" } ], "mass": 16573.0, "length": 148, "protein_name": "Proteasome chaperone 4", "gene_name": "POC4", "organism": "Yeast", "refseq_name": "Poc4p", "refseq_ac": [ { "id": "NP_015181", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015181", "type": "external" } ], "gene_names_uniprotkb": "POC4; DMP1", "gene_names_refseq": "DMP1; PBA4; POC4", "protein_names_uniprotkb": "Proteasome chaperone 4", "protein_names_refseq": "Poc4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL144W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;14562106;15161972;17322287;17707236;18278057;22814378;24374639;8948103;9169875", "class_list": "", "function": "Involved in 20S proteasome assembly, facilitating the alpha-ring formation. Involved in maintenance of telomere length., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3M5;Q6Q5F7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0032991 protein-containing complex", "go_biological_process": "GO:0043248 proteasome assembly;GO:0080129 proteasome core complex assembly;GO:0051131 chaperone-mediated protein complex assembly", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q12245-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12255-1", "uniprot_id": [ { "id": "NYV1_YEAST", "url": "https://www.uniprot.org/uniprot/Q12255", "type": "external" } ], "mass": 28964.0, "length": 253, "protein_name": "Vacuolar v-SNARE NYV1", "gene_name": "NYV1", "organism": "Yeast", "refseq_name": "Nyv1p", "refseq_ac": [ { "id": "NP_013194", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013194", "type": "external" } ], "gene_names_uniprotkb": "NYV1; MAM2", "gene_names_refseq": "MAM2; NYV1", "protein_names_uniprotkb": "Vacuolar v-SNARE NYV1; New v-SNARE 1; R-SNARE NYV1; Synaptobrevin NYV1", "protein_names_refseq": "Nyv1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR093C); (R-SCE-199992)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "10385523;10734188;11080502;11823419;14562095;14562106;14734531;16855025;17322287;19779198;23749301;24374639;33481703;33491328;9144293;9169871", "class_list": "", "function": "Vacuolar v-SNARE required for docking. Only involved in homotypic vacuole fusion. Required for Ca(2+) efflux from the vacuolar lumen, a required signal for subsequent membrane fusion events, by inhibiting vacuolar Ca(2+)-ATPase PMC1 and promoting Ca(2+) release when forming trans-SNARE assemblies during the docking step., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY93", "ec_number_list": [], "go_molecular_function": "GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005774 vacuolar membrane;GO:0031201 SNARE complex;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0042144 vacuole fusion, non-autophagic;GO:0006886 intracellular protein transport;GO:0016192 vesicle-mediated transport;GO:0006906 vesicle fusion;GO:0099500 vesicle fusion to plasma membrane", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q12255-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12270-1", "uniprot_id": [ { "id": "RBD2_YEAST", "url": "https://www.uniprot.org/uniprot/Q12270", "type": "external" } ], "mass": 29500.0, "length": 262, "protein_name": "Rhomboid-type serine protease 2", "gene_name": "RBD2", "organism": "Yeast", "refseq_name": "putative rhomboid protease RBD2", "refseq_ac": [ { "id": "NP_015078", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015078", "type": "external" } ], "gene_names_uniprotkb": "RBD2", "gene_names_refseq": "RBD2", "protein_names_uniprotkb": "Rhomboid-type serine protease 2; 3.4.21.105; Rhomboid protein 2", "protein_names_refseq": "putative rhomboid protease RBD2", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL246C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12774122;14562095;14562106;15263065;16847258;24374639;9169875", "class_list": "", "function": "Probable rhomboid-type serine protease that catalyzes intramembrane proteolysis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3C5", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0034399 nuclear periphery", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q12270-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12276-1", "uniprot_id": [ { "id": "HER1_YEAST", "url": "https://www.uniprot.org/uniprot/Q12276", "type": "external" } ], "mass": 139458.0, "length": 1246, "protein_name": "HMG2-induced ER-remodeling protein 1", "gene_name": "HER1", "organism": "Yeast", "refseq_name": "Her1p", "refseq_ac": [ { "id": "NP_014870", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014870", "type": "external" } ], "gene_names_uniprotkb": "HER1; YOR50-17", "gene_names_refseq": "HER1", "protein_names_uniprotkb": "HMG2-induced ER-remodeling protein 1", "protein_names_refseq": "Her1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR227W)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "14562095;14562106;16702403;17287358;17330950;17563356;18407956;18667535;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;23749301;24374639;32597660;33229814;33481703;33491328;8840505;9169874", "class_list": "", "function": "Required for HMG2-induced endoplasmic reticulum-remodeling., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 13, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 13, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 13, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 64, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 12, "binding_glycan_count": 0, "secondary_ac_list": "D6W2T1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0007029 endoplasmic reticulum organization", "synthesized_glycan_count": 0, "hit_score": 3.9, "record_id": "Q12276-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12334-1", "uniprot_id": [ { "id": "SCM3_YEAST", "url": "https://www.uniprot.org/uniprot/Q12334", "type": "external" } ], "mass": 25754.0, "length": 223, "protein_name": "Protein SCM3", "gene_name": "SCM3", "organism": "Yeast", "refseq_name": "Scm3p", "refseq_ac": [ { "id": "NP_010142", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010142", "type": "external" } ], "gene_names_uniprotkb": "SCM3; D2155", "gene_names_refseq": "SCM3", "protein_names_uniprotkb": "Protein SCM3; Suppressor of chromosome missegregation protein 3", "protein_names_refseq": "Scm3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL139C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "12748633;14562095;14562106;17322287;22218487;22814378;24374639;32079723;32597660;33481703;33491328;8972577;9169867", "class_list": "", "function": "Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRK9", "ec_number_list": [], "go_molecular_function": "GO:0042393 histone binding;GO:0097030 CENP-A containing nucleosome binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000779 condensed chromosome, centromeric region", "go_biological_process": "GO:0051382 kinetochore assembly;GO:0071459 protein localization to chromosome, centromeric region;GO:0007059 chromosome segregation;GO:0000086 G2/M transition of mitotic cell cycle;GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q12334-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12344-1", "uniprot_id": [ { "id": "GYP5_YEAST", "url": "https://www.uniprot.org/uniprot/Q12344", "type": "external" } ], "mass": 101800.0, "length": 894, "protein_name": "GTPase-activating protein GYP5", "gene_name": "GYP5", "organism": "Yeast", "refseq_name": "GTPase-activating protein GYP5", "refseq_ac": [ { "id": "NP_015075", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015075", "type": "external" } ], "gene_names_uniprotkb": "GYP5", "gene_names_refseq": "GYP5", "protein_names_uniprotkb": "GTPase-activating protein GYP5", "protein_names_refseq": "GTPase-activating protein GYP5", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL249C); (R-SCE-6811440)", "pathway_count": 2, "publication_count": 22, "publication_id_list": "10679030;12189143;14562095;14562106;15331637;15802519;17287358;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;21177495;23749301;24374639;32597660;33481703;33491328;9169875", "class_list": "", "function": "GTPase-activating protein which accelerates the GTP hydrolysis rate of YPT1 and SEC4. Involved in ER to Golgi trafficking and polarized exocytosis., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 43, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3C2", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005798 Golgi-associated vesicle;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0000131 incipient cellular bud site", "go_biological_process": "GO:0015031 protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0016192 vesicle-mediated transport;GO:0006887 exocytosis", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "Q12344-1", "record_type": "protein", "filter_code": "0000000.0100101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12365-1", "uniprot_id": [ { "id": "BBP1_YEAST", "url": "https://www.uniprot.org/uniprot/Q12365", "type": "external" } ], "mass": 45384.0, "length": 385, "protein_name": "Spindle pole component BBP1", "gene_name": "BBP1", "organism": "Yeast", "refseq_name": "Bbp1p", "refseq_ac": [ { "id": "NP_015068", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015068", "type": "external" } ], "gene_names_uniprotkb": "BBP1; P0745", "gene_names_refseq": "BBP1", "protein_names_uniprotkb": "Spindle pole component BBP1; BFR1-binding protein 1", "protein_names_refseq": "Bbp1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL255W)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "10654940;14562106;14767068;15665377;17322287;17330950;18407956;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;24374639;24909858;32597660;33481703;33491328;9169875", "class_list": "", "function": "Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication. Connects the central plaque of the SPB with the half-bridge. Required for proper localization of CDC5 at the SPB and for proper M-phase progression., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 23, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3B6", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0016020 membrane;GO:0005816 spindle pole body;GO:0005823 central plaque of spindle pole body", "go_biological_process": "GO:0030474 spindle pole body duplication;GO:0071988 protein localization to spindle pole body;GO:1990608 mitotic spindle pole body localization", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "Q12365-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12389-1", "uniprot_id": [ { "id": "DBP10_YEAST", "url": "https://www.uniprot.org/uniprot/Q12389", "type": "external" } ], "mass": 112946.0, "length": 995, "protein_name": "ATP-dependent RNA helicase DBP10", "gene_name": "DBP10", "organism": "Yeast", "refseq_name": "ATP-dependent RNA helicase DBP10", "refseq_ac": [ { "id": "NP_010253", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010253", "type": "external" } ], "gene_names_uniprotkb": "DBP10; D2770", "gene_names_refseq": "DBP10", "protein_names_uniprotkb": "ATP-dependent RNA helicase DBP10; 3.6.4.13; DEAD box protein 10", "protein_names_refseq": "ATP-dependent RNA helicase DBP10", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL031W)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "10871363;11875433;15100437;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21725298;23749301;24374639;24909858;32597660;33481703;33491328;9046088;9169867", "class_list": "", "function": "ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRW1", "ec_number_list": [ { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "5.6.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.4", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0016887 ATP hydrolysis activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor", "go_biological_process": "GO:0006364 rRNA processing;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:1902626 assembly of large subunit precursor of preribosome", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "Q12389-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12411-1", "uniprot_id": [ { "id": "MPC70_YEAST", "url": "https://www.uniprot.org/uniprot/Q12411", "type": "external" } ], "mass": 69878.0, "length": 609, "protein_name": "Sporulation-specific protein 21", "gene_name": "SPO21", "organism": "Yeast", "refseq_name": "Spo21p", "refseq_ac": [ { "id": "NP_014550", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014550", "type": "external" } ], "gene_names_uniprotkb": "SPO21; MPC70", "gene_names_refseq": "MPC70; SPO21", "protein_names_uniprotkb": "Sporulation-specific protein 21; Meiotic plaque component protein 70", "protein_names_refseq": "Spo21p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL091W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10899120;11244080;11408572;11973299;12796288;21126336;24374639;33491328;8533473;9169874", "class_list": "", "function": "Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation. May provide a meiosis-specific scaffold for the assembly of other proteins on spindle pole bodies (SPBs), and may be a limiting component for SPB formation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1X7", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005816 spindle pole body;GO:0005628 prospore membrane;GO:0035974 meiotic spindle pole body", "go_biological_process": "GO:0051301 cell division;GO:0051321 meiotic cell cycle;GO:0032120 ascospore-type prospore membrane formation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q12411-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12417-1", "uniprot_id": [ { "id": "PRP46_YEAST", "url": "https://www.uniprot.org/uniprot/Q12417", "type": "external" } ], "mass": 50700.0, "length": 451, "protein_name": "Pre-mRNA-splicing factor PRP46", "gene_name": "PRP46", "organism": "Yeast", "refseq_name": "mRNA splicing protein PRP46", "refseq_ac": [ { "id": "NP_015174", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015174", "type": "external" } ], "gene_names_uniprotkb": "PRP46; CWC1; NTC50; P2594", "gene_names_refseq": "NTC50; PRP46", "protein_names_uniprotkb": "Pre-mRNA-splicing factor PRP46; Complexed with CEF1 protein 1; PRP nineteen-associated complex protein 50; PRP19-associated complex protein 50; Pre-mRNA-processing protein 46", "protein_names_refseq": "mRNA splicing protein PRP46", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL151C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "11079560;11884590;12088152;12554883;14562095;14562106;14690591;18407956;24374639;33491328;8948103;9169875", "class_list": "", "function": "Involved in pre-mRNA splicing. May also be required for cell cycle progression at G2/M (By similarity)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3L8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005681 spliceosomal complex;GO:0071013 catalytic step 2 spliceosome;GO:0000974 Prp19 complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q12417-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12421-1", "uniprot_id": [ { "id": "ATG31_YEAST", "url": "https://www.uniprot.org/uniprot/Q12421", "type": "external" } ], "mass": 22191.0, "length": 196, "protein_name": "Autophagy-related protein 31", "gene_name": "ATG31", "organism": "Yeast", "refseq_name": "Atg31p", "refseq_ac": [ { "id": "NP_010305", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010305", "type": "external" } ], "gene_names_uniprotkb": "ATG31; CIS1; PZD196; YD9335.08c", "gene_names_refseq": "ATG31; CIS1", "protein_names_uniprotkb": "Autophagy-related protein 31; CIK1 suppressor protein 1; Protein CIS1", "protein_names_refseq": "Atg31p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR022C)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "14562095;14562106;17322287;17362880;18287526;19337029;19755117;19779198;19793921;24374639;25773276;33481703;33491328;8896275;9169867;9348527", "class_list": "", "function": "Plays a role in starvation-induced autophagy (PubMed:17362880, PubMed:18287526, PubMed:19755117, PubMed:25773276). Involved in mitophagy (PubMed:19793921). Functions with ATG17 and ATG29 at the preautophagosomal structure (PAS) in order to form normal autophagosomes under starvation conditions (PubMed:17362880, PubMed:18287526, PubMed:25773276). May be involved in microtubule function, such as chromosome segregation and karyogamy (PubMed:9348527)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS08;Q03939", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005874 microtubule;GO:0000407 phagophore assembly site;GO:1990316 Atg1/ULK1 kinase complex", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0007059 chromosome segregation;GO:0015031 protein transport;GO:0042594 response to starvation;GO:0006914 autophagy", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q12421-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12447-1", "uniprot_id": [ { "id": "PAA1_YEAST", "url": "https://www.uniprot.org/uniprot/Q12447", "type": "external" } ], "mass": 21947.0, "length": 191, "protein_name": "Polyamine N-acetyltransferase 1", "gene_name": "PAA1", "organism": "Yeast", "refseq_name": "polyamine acetyltransferase", "refseq_ac": [ { "id": "NP_010356", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010356", "type": "external" } ], "gene_names_uniprotkb": "PAA1", "gene_names_refseq": "PAA1", "protein_names_uniprotkb": "Polyamine N-acetyltransferase 1; 2.3.1.-; Arylalkylamine N-acetyltransferase homolog; scAANAT", "protein_names_refseq": "polyamine acetyltransferase", "tax_id": 559292, "disease": "advanced sleep phase syndrome (Disease Ontology:DOID:0050628); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (sce:YDR071C); (R-SCE-209931)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "11559708;14562095;14562106;15723835;17322287;24374639;33481703;33491328;9169867", "class_list": "", "function": "Acetylates spermine and probably also other polyamines such as putrescine or spermidine. May regulate the levels of polyamines on chromosomal DNA, which would modify chromatin structure and affect transcription or replication. Also able to acetylate arylalkylamines such as tryptamine and serotonin in vitro., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS57", "ec_number_list": [ { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" } ], "go_molecular_function": "GO:0004145 diamine N-acetyltransferase activity;GO:0004059 aralkylamine N-acetyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q12447-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12450-1", "uniprot_id": [ { "id": "ERP4_YEAST", "url": "https://www.uniprot.org/uniprot/Q12450", "type": "external" } ], "mass": 23515.0, "length": 207, "protein_name": "Protein ERP4", "gene_name": "ERP4", "organism": "Yeast", "refseq_name": "Erp4p", "refseq_ac": [ { "id": "NP_014659", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014659", "type": "external" } ], "gene_names_uniprotkb": "ERP4", "gene_names_refseq": "ERP4", "protein_names_uniprotkb": "Protein ERP4", "protein_names_refseq": "Erp4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR016C); (R-SCE-6807878); (R-SCE-6811434)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "10359606;14562106;17322287;24374639;9169874", "class_list": "", "function": "Involved in vesicular protein trafficking., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W282", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016020 membrane;GO:0030134 COPII-coated ER to Golgi transport vesicle;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030 Golgi organization;GO:0006621 protein retention in ER lumen", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q12450-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12451-1", "uniprot_id": [ { "id": "OSH2_YEAST", "url": "https://www.uniprot.org/uniprot/Q12451", "type": "external" } ], "mass": 145796.0, "length": 1283, "protein_name": "Oxysterol-binding protein homolog 2", "gene_name": "OSH2", "organism": "Yeast", "refseq_name": "oxysterol-binding protein related protein OSH2", "refseq_ac": [ { "id": "NP_010265", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010265", "type": "external" } ], "gene_names_uniprotkb": "OSH2; D2845", "gene_names_refseq": "OSH2", "protein_names_uniprotkb": "Oxysterol-binding protein homolog 2; ORP 2; OSBP-related protein 2; Oxysterol-binding protein-related protein 2", "protein_names_refseq": "oxysterol-binding protein related protein OSH2", "tax_id": 559292, "disease": "autosomal dominant nonsyndromic deafness 67 (Disease Ontology:DOID:0110588); cholangiocarcinoma (Disease Ontology:DOID:4947); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (sce:YDL019C); (R-SCE-192105)", "pathway_count": 2, "publication_count": 29, "publication_id_list": "11238399;11408574;12727870;14562106;15023338;15173322;15665377;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20008566;20702584;21126336;21177495;22218487;23749301;24213531;24374639;30516470;32597660;33229814;33481703;33491328;9169867", "class_list": "", "function": "Lipid transport protein (LTP) involved in non-vesicular transfer of lipids between membranes. Functions in phosphoinositide-coupled directional transport of various lipids by carrying the lipid molecule in a hydrophobic pocket and transferring it between membranes through the cytosol. Involved in maintenance of intracellular sterol distribution and homeostasis (PubMed:15173322). Binds and transports sterol (PubMed:20008566). Plays a role in the positive regulation of vesicular transport of ceramide from the ER to the Golgi, negatively regulating COPII-mediated ER export of cargos (PubMed:24213531)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 54, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6VRX1;P89891", "ec_number_list": [], "go_molecular_function": "GO:0008289 lipid binding;GO:0032934 sterol binding;GO:0120015 sterol transfer activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0097038 perinuclear endoplasmic reticulum", "go_biological_process": "GO:0006897 endocytosis;GO:0006887 exocytosis;GO:0030011 maintenance of cell polarity;GO:0034727 piecemeal microautophagy of the nucleus;GO:0035621 ER to Golgi ceramide transport", "synthesized_glycan_count": 0, "hit_score": 3.5, "record_id": "Q12451-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12453-1", "uniprot_id": [ { "id": "CEX1_YEAST", "url": "https://www.uniprot.org/uniprot/Q12453", "type": "external" } ], "mass": 84769.0, "length": 761, "protein_name": "Cytoplasmic export protein 1", "gene_name": "CEX1", "organism": "Yeast", "refseq_name": "COPI-interacting protein CEX1", "refseq_ac": [ { "id": "NP_014755", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014755", "type": "external" } ], "gene_names_uniprotkb": "CEX1; O3240; YOR3240w", "gene_names_refseq": "CEX1", "protein_names_uniprotkb": "Cytoplasmic export protein 1", "protein_names_refseq": "COPI-interacting protein CEX1", "tax_id": 559292, "disease": "hereditary ataxia (Disease Ontology:DOID:0050951); autosomal recessive spinocerebellar ataxia 21 (Disease Ontology:DOID:0111155)", "pathway": " (sce:YOR112W)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "14562095;14562106;17203074;17330950;17563356;19779198;23749301;24374639;30516470;32597660;33229814;33491328;8904341;9169874;9200815", "class_list": "", "function": "Component of the nuclear tRNA export machinery that my collect tRNA from the nuclear tRNA export receptors of the aminoacylation-dependent export and may deliver aminoacylated tRNAs to the translation machinery pathway at the nuclear pore complex., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6W2H1", "ec_number_list": [], "go_molecular_function": "GO:0000049 tRNA binding", "go_cellular_component": "GO:0005643 nuclear pore;GO:0005737 cytoplasm", "go_biological_process": "GO:0006409 tRNA export from nucleus;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q12453-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12488-1", "uniprot_id": [ { "id": "PSF1_YEAST", "url": "https://www.uniprot.org/uniprot/Q12488", "type": "external" } ], "mass": 24204.0, "length": 208, "protein_name": "DNA replication complex GINS protein PSF1", "gene_name": "PSF1", "organism": "Yeast", "refseq_name": "DNA replication protein PSF1", "refseq_ac": [ { "id": "NP_010296", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010296", "type": "external" } ], "gene_names_uniprotkb": "PSF1; PZA208; YD8119.18", "gene_names_refseq": "CDC101; PSF1", "protein_names_uniprotkb": "DNA replication complex GINS protein PSF1; Partner of Sld five 1", "protein_names_refseq": "DNA replication protein PSF1", "tax_id": 559292, "disease": "immunodeficiency 55 (Disease Ontology:DOID:0111993)", "pathway": " (sce:YDR013W); (R-SCE-176974)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "12730134;14562106;14690591;17322287;22814378;24374639;33491328;8896275;9169867", "class_list": "", "function": "Required for DNA replication. Functions as part of the GINS complex which plays an essential role in the initiation of DNA replication by binding to DNA replication origins and facilitating the assembly of the DNA replication machinery. Required for the chromatin binding of CDC45., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRZ9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0031261 DNA replication preinitiation complex;GO:0043596 nuclear replication fork;GO:0005634 nucleus;GO:0000811 GINS complex;GO:0071162 CMG complex", "go_biological_process": "GO:0006260 DNA replication;GO:1902983 DNA strand elongation involved in mitotic DNA replication;GO:0000727 double-strand break repair via break-induced replication;GO:0006261 DNA-templated DNA replication", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q12488-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12510-1", "uniprot_id": [ { "id": "CMR1_YEAST", "url": "https://www.uniprot.org/uniprot/Q12510", "type": "external" } ], "mass": 59156.0, "length": 522, "protein_name": "DNA damage-binding protein CMR1", "gene_name": "CMR1", "organism": "Yeast", "refseq_name": "Cmr1p", "refseq_ac": [ { "id": "NP_010125", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010125", "type": "external" } ], "gene_names_uniprotkb": "CMR1; D1536", "gene_names_refseq": "CMR1", "protein_names_uniprotkb": "DNA damage-binding protein CMR1; Changed mutation rate protein 1", "protein_names_refseq": "Cmr1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL156W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "14562095;14562106;17287358;18407956;19779198;20702584;21126336;22367945;23349438;23749301;24374639;32597660;33481703;33491328;34965436;8972581;9169867", "class_list": "", "function": "DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA in vitro (PubMed:22367945). May be involved in DNA-metabolic processes (PubMed:23349438)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRJ4", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000785 chromatin;GO:0034399 nuclear periphery", "go_biological_process": "GO:2000001 regulation of DNA damage checkpoint;GO:0006974 DNA damage response", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q12510-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12518-1", "uniprot_id": [ { "id": "ENT1_YEAST", "url": "https://www.uniprot.org/uniprot/Q12518", "type": "external" } ], "mass": 52352.0, "length": 454, "protein_name": "Epsin-1", "gene_name": "ENT1", "organism": "Yeast", "refseq_name": "epsin", "refseq_ac": [ { "id": "NP_010120", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010120", "type": "external" } ], "gene_names_uniprotkb": "ENT1", "gene_names_refseq": "ENT1", "protein_names_uniprotkb": "Epsin-1", "protein_names_refseq": "epsin", "tax_id": 559292, "disease": "middle cerebral artery infarction (Disease Ontology:DOID:3525)", "pathway": " (sce:YDL161W); (R-SCE-8856825)", "pathway_count": 2, "publication_count": 24, "publication_id_list": "10449404;11694597;12529323;13679512;15665377;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22106047;22218487;23749301;24374639;32597660;33481703;33491328;9169867", "class_list": "", "function": "Binds to membranes enriched in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin. Negatively regulated via phosphorylation., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 24, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRI8", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0030276 clathrin binding;GO:0043130 ubiquitin binding;GO:0070530 K63-linked polyubiquitin modification-dependent protein binding", "go_cellular_component": "GO:0030125 clathrin vesicle coat;GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005769 early endosome;GO:0005886 plasma membrane", "go_biological_process": "GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0000147 actin cortical patch assembly", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "Q12518-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12527-1", "uniprot_id": [ { "id": "ATG11_YEAST", "url": "https://www.uniprot.org/uniprot/Q12527", "type": "external" } ], "mass": 135025.0, "length": 1178, "protein_name": "Autophagy-related protein 11", "gene_name": "ATG11", "organism": "Yeast", "refseq_name": "autophagy protein ATG11", "refseq_ac": [ { "id": "NP_015374", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015374", "type": "external" } ], "gene_names_uniprotkb": "ATG11; CVT9; YP9499.07c", "gene_names_refseq": "ATG11; CVT3; CVT9", "protein_names_uniprotkb": "Autophagy-related protein 11; Cytoplasm to vacuole targeting protein 9", "protein_names_refseq": "autophagy protein ATG11", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR049C); (R-SCE-1632852)", "pathway_count": 2, "publication_count": 51, "publication_id_list": "10995454;11264288;11309418;11675395;12479808;14536056;14562095;14562106;15138258;15659643;16901900;17012830;17178909;17192412;17295840;18077553;18287526;18407956;18497569;18625846;18701704;18725539;18818209;19061865;19303850;19371383;19619494;19619495;19795423;19823750;20639194;20647741;20855505;21343297;21429936;21757540;22157017;22308029;22509044;22768199;23337777;23559066;23749301;24374639;31356628;32597660;33491328;34965436;38964378;8663607;9169875", "class_list": "", "function": "Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation, through its interaction with ATG32. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for ATG9 anterograde transport from the mitochondria to the PAS. Also recruits the ATG19-prAPE1 complex to the PAS. Required for the Cvt vesicles completion. Plays a significant role in life span extension., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W457", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0019901 protein kinase binding;GO:0000149 SNARE binding", "go_cellular_component": "GO:0005774 vacuolar membrane;GO:0034045 phagophore assembly site membrane;GO:0000407 phagophore assembly site;GO:1990316 Atg1/ULK1 kinase complex;GO:0071957 old mitotic spindle pole body", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0007059 chromosome segregation;GO:0006914 autophagy;GO:0034497 protein localization to phagophore assembly site;GO:0000422 autophagy of mitochondrion", "synthesized_glycan_count": 0, "hit_score": 5.2, "record_id": "Q12527-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12675-1", "uniprot_id": [ { "id": "ATC4_YEAST", "url": "https://www.uniprot.org/uniprot/Q12675", "type": "external" } ], "mass": 182619.0, "length": 1612, "protein_name": "Phospholipid-transporting ATPase DNF2", "gene_name": "DNF2", "organism": "Yeast", "refseq_name": "aminophospholipid-translocating P4-type ATPase DNF2", "refseq_ac": [ { "id": "NP_010378", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010378", "type": "external" } ], "gene_names_uniprotkb": "DNF2; YD8557.01", "gene_names_refseq": "DNF2", "protein_names_uniprotkb": "Phospholipid-transporting ATPase DNF2; 7.6.2.1; Flippase DNF2", "protein_names_refseq": "aminophospholipid-translocating P4-type ATPase DNF2", "tax_id": 559292, "disease": "progressive familial intrahepatic cholestasis (Disease Ontology:DOID:0070221)", "pathway": " (sce:YDR093W)", "pathway_count": 1, "publication_count": 27, "publication_id_list": "12221123;12631737;15665377;16847258;17330950;18199685;18407956;19684113;19779198;19795423;19823750;19966303;20702584;22106047;22218487;23749301;24374639;24909858;27235400;30824614;32597660;33060204;33320091;33481703;33491328;34965436;9169867", "class_list": "", "function": "Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of glucosylceramide, phosphatidylcholine, phosphatidylethanolamine, and small amounts of phosphatidylserine from the lumenal to the cytosolic leaflet of the cell membrane and ensures the maintenance of asymmetric distribution of phospholipids (PubMed:12631737, PubMed:33060204, PubMed:33320091). Does not appear to transport sphingomyelin, inositol phosphoceramide or phosphatidic acid (PubMed:12631737, PubMed:33320091). Required for efficient endocytosis (PubMed:12631737). Required for protein transport from Golgi to vacuoles (PubMed:12221123)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 35, "reported_mutagensis": 12, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS80", "ec_number_list": [ { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0090554 phosphatidylcholine floppase activity;GO:0090556 phosphatidylserine floppase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:1990531 phospholipid-translocating ATPase complex;GO:0005935 cellular bud neck", "go_biological_process": "GO:0006897 endocytosis;GO:0015031 protein transport;GO:0045332 phospholipid translocation;GO:0007163 establishment or maintenance of cell polarity;GO:0099040 ceramide translocation", "synthesized_glycan_count": 0, "hit_score": 2.8, "record_id": "Q12675-1", "record_type": "protein", "filter_code": "0000000.0100111.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12692-1", "uniprot_id": [ { "id": "H2AZ_YEAST", "url": "https://www.uniprot.org/uniprot/Q12692", "type": "external" } ], "mass": 14283.0, "length": 134, "protein_name": "Histone H2A.Z", "gene_name": "HTZ1", "organism": "Yeast", "refseq_name": "histone H2AZ", "refseq_ac": [ { "id": "NP_014631", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014631", "type": "external" } ], "gene_names_uniprotkb": "HTZ1; H2AZ; HTA3; O2345", "gene_names_refseq": "HTA3; HTZ1", "protein_names_uniprotkb": "Histone H2A.Z", "protein_names_refseq": "histone H2AZ", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL012C); (R-SCE-2299718)", "pathway_count": 2, "publication_count": 25, "publication_id_list": "11000274;11081628;11090616;11509669;12628191;14562095;14562106;14645854;14690608;15045029;15353583;16239142;16299513;16344463;16543222;16543223;16598039;17322287;18086883;21518795;22814378;24374639;33491328;9009827;9169874", "class_list": "", "function": "Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received (PubMed:11000274, PubMed:11081628, PubMed:11090616, PubMed:11509669, PubMed:12628191, PubMed:14645854, PubMed:14690608, PubMed:15045029, PubMed:16239142, PubMed:16344463, PubMed:16543223). Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins (PubMed:16543222). Required for the RNA polymerase II and SPT15/TBP recruitment to the target genes (PubMed:11509669). Involved in chromosome stability (PubMed:15353583). Required to target MPS3 to the inner membrane of the nuclear envelope (PubMed:21518795)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W255", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0042802 identical protein binding;GO:0046982 protein heterodimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0031490 chromatin DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0000791 euchromatin;GO:0000786 nucleosome", "go_biological_process": "GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay;GO:0006338 chromatin remodeling;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "Q12692-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12743-1", "uniprot_id": [ { "id": "DFM1_YEAST", "url": "https://www.uniprot.org/uniprot/Q12743", "type": "external" } ], "mass": 38131.0, "length": 341, "protein_name": "DER1-like family member protein 1", "gene_name": "DFM1", "organism": "Yeast", "refseq_name": "Dfm1p", "refseq_ac": [ { "id": "NP_010699", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010699", "type": "external" } ], "gene_names_uniprotkb": "DFM1; D9461.2", "gene_names_refseq": "DFM1", "protein_names_uniprotkb": "DER1-like family member protein 1", "protein_names_refseq": "Dfm1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR411C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10847680;14562095;15093775;16847258;23749301;24374639;25454947;32597660;33229814;33481703;33491328;8212897;9169867", "class_list": "", "function": "Involved in endoplasmic reticulum-associated protein degradation (ERAD) of membrane proteins; ERAD comprises protein catabolic pathways that target ER-resident proteins for degradation by the cytoplasmic proteasome (PubMed:15093775, PubMed:25454947). Functions in the ERAD-R branch together with DOA10 and YPF1; this pathway regulates protein levels in response to signaling (PubMed:25454947)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VT43;Q7LIJ5", "ec_number_list": [], "go_molecular_function": "GO:0005047 signal recognition particle binding;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0030968 endoplasmic reticulum unfolded protein response;GO:0036503 ERAD pathway;GO:1904152 regulation of retrograde protein transport, ER to cytosol", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q12743-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12745-1", "uniprot_id": [ { "id": "SEC39_YEAST", "url": "https://www.uniprot.org/uniprot/Q12745", "type": "external" } ], "mass": 82396.0, "length": 709, "protein_name": "Protein transport protein SEC39", "gene_name": "SEC39", "organism": "Yeast", "refseq_name": "Sec39p", "refseq_ac": [ { "id": "NP_013545", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013545", "type": "external" } ], "gene_names_uniprotkb": "SEC39; DSL3", "gene_names_refseq": "DSL3; SEC39", "protein_names_uniprotkb": "Protein transport protein SEC39; Dependent on SLY1-20 protein 3", "protein_names_refseq": "Sec39p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR440C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "15242642;15942868;15958492;16429126;24374639;7828914;9169871", "class_list": "", "function": "Required for protein transport between the Golgi and the endoplasmic reticulum. May contribute to tethering of coatomer-coated retrograde transport vesicles to the ER membrane through interaction with and stabilization of the SNARE complex., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ75;Q7LHI0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0070939 Dsl1/NZR complex;GO:0005635 nuclear envelope;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0015031 protein transport;GO:0016192 vesicle-mediated transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0032581 ER-dependent peroxisome organization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q12745-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q12754-1", "uniprot_id": [ { "id": "RRP12_YEAST", "url": "https://www.uniprot.org/uniprot/Q12754", "type": "external" } ], "mass": 137509.0, "length": 1228, "protein_name": "Ribosomal RNA-processing protein 12", "gene_name": "RRP12", "organism": "Yeast", "refseq_name": "mRNA-binding protein RRP12", "refseq_ac": [ { "id": "NP_015313", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015313", "type": "external" } ], "gene_names_uniprotkb": "RRP12", "gene_names_refseq": "RRP12", "protein_names_uniprotkb": "Ribosomal RNA-processing protein 12", "protein_names_refseq": "mRNA-binding protein RRP12", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL012W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "12628929;14562095;14562106;14729571;17330950;17563356;18407956;19684113;19779198;19795423;19823750;21126336;23749301;24374639;33481703;33491328;9169875", "class_list": "", "function": "In association with GSP1, required for nuclear export of both pre-40S and pre-60S ribosomal subunits. Required for the late maturation of the 18S and 5.8S rRNA of the pre-40S ribosomes and for maturation of the 25S and 5.8S rRNA of the pre-60S ribosomes., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W400;Q7LH12", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005840 ribosome;GO:0030688 preribosome, small subunit precursor", "go_biological_process": "GO:0042254 ribosome biogenesis;GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q12754-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q3E7B2-1", "uniprot_id": [ { "id": "COA3_YEAST", "url": "https://www.uniprot.org/uniprot/Q3E7B2", "type": "external" } ], "mass": 9882.0, "length": 85, "protein_name": "Cytochrome c oxidase assembly factor 3, mitochondrial", "gene_name": "COA3", "organism": "Yeast", "refseq_name": "Coa3p", "refseq_ac": [ { "id": "NP_076894", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_076894", "type": "external" } ], "gene_names_uniprotkb": "COA3; COX25; RRG10", "gene_names_refseq": "COA3; COX25; RRG10", "protein_names_uniprotkb": "Cytochrome c oxidase assembly factor 3, mitochondrial; Cytochrome c oxidase protein 25; Required for respiratory growth protein 10", "protein_names_refseq": "Coa3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL062W-A)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "11152879;14562095;14562106;16510898;16823961;19751518;20876281;21068384;22814378;24374639;8641269", "class_list": "", "function": "Required for assembly of cytochrome c oxidase (complex IV). With COX14, negatively regulates COX1 translation and is involved in MSS51 association with newly synthesized COX1., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWB9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0050821 protein stabilization;GO:0033617 mitochondrial respiratory chain complex IV assembly;GO:0070130 negative regulation of mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q3E7B2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q92331-1", "uniprot_id": [ { "id": "VPS5_YEAST", "url": "https://www.uniprot.org/uniprot/Q92331", "type": "external" } ], "mass": 76484.0, "length": 675, "protein_name": "Vacuolar protein sorting-associated protein 5", "gene_name": "VPS5", "organism": "Yeast", "refseq_name": "sorting nexin 1", "refseq_ac": [ { "id": "NP_014712", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014712", "type": "external" } ], "gene_names_uniprotkb": "VPS5; GRD2; PEP10; VPT5; YOR29-20", "gene_names_refseq": "GRD2; PEP10; VPS5; VPT5", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 5; Carboxypeptidase Y-deficient protein 10; Vacuolar protein-targeting protein 5", "protein_names_refseq": "sorting nexin 1", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR069W)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "14562106;17322287;17563356;18407956;23749301;24374639;32597660;33229814;33481703;33491328;9133743;9169874;9175702;9285823;9700157", "class_list": "", "function": "Plays a role in vesicular protein sorting. Required for retention of late Golgi membrane proteins and vacuolar biogenesis. Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport. The VPS5-VPS17 subcomplex may assemble onto the membrane to promote vesicle formation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 6, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 6, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 6, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6W2D1;E9P8U6;Q08483", "ec_number_list": [], "go_molecular_function": "GO:0032266 phosphatidylinositol-3-phosphate binding;GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005768 endosome;GO:0005829 cytosol;GO:0012505 endomembrane system;GO:0010008 endosome membrane", "go_biological_process": "GO:0045053 protein retention in Golgi apparatus;GO:0015031 protein transport;GO:0042147 retrograde transport, endosome to Golgi;GO:0032456 endocytic recycling", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "Q92331-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q99278-1", "uniprot_id": [ { "id": "MED11_YEAST", "url": "https://www.uniprot.org/uniprot/Q99278", "type": "external" } ], "mass": 13307.0, "length": 115, "protein_name": "Mediator of RNA polymerase II transcription subunit 11", "gene_name": "MED11", "organism": "Yeast", "refseq_name": "Med11p", "refseq_ac": [ { "id": "NP_013830", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013830", "type": "external" } ], "gene_names_uniprotkb": "MED11; YM9718.11C", "gene_names_refseq": "MED11", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 11; Mediator complex subunit 11", "protein_names_refseq": "Med11p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR112C)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "11555651;12191485;14562095;14562106;15175151;15477388;16002404;16076843;16263706;16885025;17101987;17192271;17322287;18691966;21498544;21725323;24374639;9169872;9812975", "class_list": "", "function": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre-initiation complex (PIC) with RNA polymerase II and the general transcription factors. The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins. The essential MED11/22 heterodimer specifically functions in promoting stable PIC formation., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZT5", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0001097 TFIIH-class transcription factor complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016592 mediator complex;GO:0070847 core mediator complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0032968 positive regulation of transcription elongation by RNA polymerase II;GO:0051123 RNA polymerase II preinitiation complex assembly", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q99278-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q99380-1", "uniprot_id": [ { "id": "OST4_YEAST", "url": "https://www.uniprot.org/uniprot/Q99380", "type": "external" } ], "mass": 3985.0, "length": 36, "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST4", "gene_name": "OST4", "organism": "Yeast", "refseq_name": "olichyl-diphosphooligosaccharide--protein glycotransferase OST4", "refseq_ac": [ { "id": "NP_010049", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010049", "type": "external" } ], "gene_names_uniprotkb": "OST4", "gene_names_refseq": "OST4", "protein_names_uniprotkb": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST4; OTase 4 kDa subunit; Oligosaccharyl transferase 4 kDa subunit; Oligosaccharyl transferase subunit OST4", "protein_names_refseq": "olichyl-diphosphooligosaccharide--protein glycotransferase OST4", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL232W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "10677492;11580295;12810948;14562095;14562106;15001703;15831493;15886282;16096345;16096346;16297388;24374639;29301962;29466327;8175708;8621712;9169867;9405463;9878773", "class_list": "", "function": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 12, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRC4", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005789 endoplasmic reticulum membrane;GO:0008250 oligosaccharyltransferase complex", "go_biological_process": "GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q99380-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9URQ5-1", "uniprot_id": [ { "id": "HTL1_YEAST", "url": "https://www.uniprot.org/uniprot/Q9URQ5", "type": "external" } ], "mass": 9180.0, "length": 78, "protein_name": "High temperature lethal protein 1", "gene_name": "HTL1", "organism": "Yeast", "refseq_name": "Htl1p", "refseq_ac": [ { "id": "NP_009949", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009949", "type": "external" } ], "gene_names_uniprotkb": "HTL1; DRT1", "gene_names_refseq": "HTL1", "protein_names_uniprotkb": "High temperature lethal protein 1; Chromatin structure-remodeling complex protein HTL1", "protein_names_refseq": "Htl1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR020W-B)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "11571756;12417720;12684875;14562106;14729968;1574125;16204215;17322287;22814378;24374639;33481703;33491328", "class_list": "", "function": "Required for cell cycle progression through G2/M transition at temperatures higher than 33 degrees Celsius. Component of the chromatin structure-remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton. When associated with the RSC complex, may act coordinately with PKC1 to regulate G2/M transition. Together with LDB7, NPL6, RSC3, RSC30 components, defines a fungal-specific module within the RSC complex that plays a role in many cellular functions including the maintenance of cell wall integrity., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR30", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0016586 RSC-type complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0000086 G2/M transition of mitotic cell cycle;GO:0006368 transcription elongation by RNA polymerase II;GO:0006337 nucleosome disassembly", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9URQ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A2P2R3-1", "uniprot_id": [ { "id": "YM084_YEAST", "url": "https://www.uniprot.org/uniprot/A2P2R3", "type": "external" } ], "mass": 29272.0, "length": 262, "protein_name": "Putative glutamine--fructose-6-phosphate aminotransferase [isomerizing]", "gene_name": "", "organism": "Yeast", "refseq_name": "putative glutamine--fructose-6-phosphate transaminase", "refseq_ac": [ { "id": "NP_013801", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013801", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Putative glutamine--fructose-6-phosphate aminotransferase [isomerizing]; 2.6.1.16; D-fructose-6-phosphate amidotransferase; GFAT; Hexosephosphate aminotransferase", "protein_names_refseq": "putative glutamine--fructose-6-phosphate transaminase", "tax_id": 559292, "disease": "congenital myasthenic syndrome 12 (Disease Ontology:DOID:0110660); familial hyperlipidemia (Disease Ontology:DOID:1168); Machado-Joseph disease (Disease Ontology:DOID:1440); hyperinsulinism (Disease Ontology:DOID:2018); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YMR084W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12844361;17322287;24374639;9169872", "class_list": "", "function": "Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZQ7;E9P8R5;Q3E7C0;Q6B308;Q6WV01", "ec_number_list": [ { "id": "2.6.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.16", "type": "external" } ], "go_molecular_function": "GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity", "go_cellular_component": "", "go_biological_process": "GO:0006487 protein N-linked glycosylation;GO:0006048 UDP-N-acetylglucosamine biosynthetic process;GO:0006047 UDP-N-acetylglucosamine metabolic process;GO:0006002 fructose 6-phosphate metabolic process;GO:0006031 chitin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A2P2R3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O14468-1", "uniprot_id": [ { "id": "YO304_YEAST", "url": "https://www.uniprot.org/uniprot/O14468", "type": "external" } ], "mass": 8617.0, "length": 76, "protein_name": "Uncharacterized protein YOR304C-A", "gene_name": "", "organism": "Yeast", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein YOR304C-A", "protein_names_refseq": "", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR304C-A)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;24374639;24909858;33481703;33491328;9169874", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W304", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005933 cellular bud;GO:0005934 cellular bud tip;GO:0005935 cellular bud neck;GO:0043332 mating projection tip", "go_biological_process": "GO:0051017 actin filament bundle assembly", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "O14468-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O74302-1", "uniprot_id": [ { "id": "YD13A_YEAST", "url": "https://www.uniprot.org/uniprot/O74302", "type": "external" } ], "mass": 49009.0, "length": 440, "protein_name": "Transposon Ty1-DR4 Gag polyprotein", "gene_name": "TY1A-DR4", "organism": "Yeast", "refseq_name": "gag protein", "refseq_ac": [ { "id": "NP_058149", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_058149", "type": "external" } ], "gene_names_uniprotkb": "TY1A-DR4; YDRCTy1-3 GAG", "gene_names_refseq": "", "protein_names_uniprotkb": "Transposon Ty1-DR4 Gag polyprotein; Gag-p45; Gag-p49; TY1A; TYA; Transposon Ty1 protein A; p54; p58", "protein_names_refseq": "gag protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR261C-C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11884596;16093660;24374639;9169867;9582191", "class_list": "", "function": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VSP5", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "O74302-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P00498-1", "uniprot_id": [ { "id": "HIS1_YEAST", "url": "https://www.uniprot.org/uniprot/P00498", "type": "external" } ], "mass": 32266.0, "length": 297, "protein_name": "ATP phosphoribosyltransferase", "gene_name": "HIS1", "organism": "Yeast", "refseq_name": "ATP phosphoribosyltransferase", "refseq_ac": [ { "id": "NP_010975", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010975", "type": "external" } ], "gene_names_uniprotkb": "HIS1", "gene_names_refseq": "HIS1", "protein_names_uniprotkb": "ATP phosphoribosyltransferase; 2.4.2.17; ATP-PRTase; ATP-PRT", "protein_names_refseq": "ATP phosphoribosyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YER055C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "22814378;24374639;33491328;6300123;9169868", "class_list": "", "function": "Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of the enzymatic activity (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLV8", "ec_number_list": [ { "id": "2.4.2.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.17", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0003879 ATP phosphoribosyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0000105 L-histidine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P00498-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P00912-1", "uniprot_id": [ { "id": "TRPF_YEAST", "url": "https://www.uniprot.org/uniprot/P00912", "type": "external" } ], "mass": 24144.0, "length": 224, "protein_name": "N-(5'-phosphoribosyl)anthranilate isomerase", "gene_name": "TRP1", "organism": "Yeast", "refseq_name": "phosphoribosylanthranilate isomerase TRP1", "refseq_ac": [ { "id": "NP_010290", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010290", "type": "external" } ], "gene_names_uniprotkb": "TRP1", "gene_names_refseq": "TRP1", "protein_names_uniprotkb": "N-(5'-phosphoribosyl)anthranilate isomerase; 5.3.1.24; PRAI", "protein_names_refseq": "phosphoribosylanthranilate isomerase TRP1", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR007W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562106;15087486;21126336;24374639;33491328;3785376;6248420;8154181;9169867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRZ5;Q03448;Q12131;Q70DA4;Q70DA7;Q70DB2;Q7LHE0", "ec_number_list": [ { "id": "5.3.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.24", "type": "external" } ], "go_molecular_function": "GO:0004640 phosphoribosylanthranilate isomerase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0000162 L-tryptophan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P00912-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P01098-1", "uniprot_id": [ { "id": "STF1_YEAST", "url": "https://www.uniprot.org/uniprot/P01098", "type": "external" } ], "mass": 10062.0, "length": 86, "protein_name": "F(1)-ATPase inhibitor STF1, mitochondrial", "gene_name": "STF1", "organism": "Yeast", "refseq_name": "ATPase-binding protein", "refseq_ac": [ { "id": "NP_010152", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010152", "type": "external" } ], "gene_names_uniprotkb": "STF1; AIS2; YDL130BW", "gene_names_refseq": "AIS2; STF1", "protein_names_uniprotkb": "F(1)-ATPase inhibitor STF1, mitochondrial; 9 kDa ATPase inhibitor complex-stabilizing factor; 9K; Stabilizing factor 1", "protein_names_refseq": "ATPase-binding protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL130W-A)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "12167646;12186878;12809520;18407956;2172220;24374639;2907329;33491328;6194151;6200468;9169867", "class_list": "", "function": "Endogenous low-affinity ATPase inhibitor, which inhibits specifically the reverse ATPase reaction of mitochondrial F(1)F(0)-type ATP synthase (PubMed:12809520). Found to stabilize, together with STF2, a complex of intrinsic ATPase inhibitor INH1 and proton-translocating ATPase in mitochondrial membranes (PubMed:6200468). Binds directly to purified F1-ATPase (PubMed:2172220)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRL9", "ec_number_list": [], "go_molecular_function": "GO:0051117 ATPase binding;GO:0042030 ATPase inhibitor activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0032780 negative regulation of ATP-dependent activity", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P01098-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P02407-1", "uniprot_id": [ { "id": "RS17A_YEAST", "url": "https://www.uniprot.org/uniprot/P02407", "type": "external" } ], "mass": 15788.0, "length": 136, "protein_name": "Small ribosomal subunit protein eS17A", "gene_name": "RPS17A", "organism": "Yeast", "refseq_name": "40S ribosomal protein eS17 RPS17A", "refseq_ac": [ { "id": "NP_013688", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013688", "type": "external" } ], "gene_names_uniprotkb": "RPS17A; RP51A", "gene_names_refseq": "RP51A; RPL51A; RPS17A", "protein_names_uniprotkb": "Small ribosomal subunit protein eS17A; 40S ribosomal protein S17-A; RP51A", "protein_names_refseq": "40S ribosomal protein eS17 RPS17A", "tax_id": 559292, "disease": "intrinsic cardiomyopathy (Disease Ontology:DOID:0060036); Diamond-Blackfan anemia 4 (Disease Ontology:DOID:0111890); Diamond-Blackfan anemia (Disease Ontology:DOID:1339)", "pathway": " (sce:YML024W); (R-SCE-156827); (R-SCE-1799339); (R-SCE-6791226); (R-SCE-72649); (R-SCE-72689); (R-SCE-72695); (R-SCE-72702); (R-SCE-72706); (R-SCE-975956); (R-SCE-975957); (R-SCE-9954714)", "pathway_count": 12, "publication_count": 15, "publication_id_list": "14562095;14562106;15665377;17287358;21109664;21126336;22096102;22218487;24374639;24524803;30516470;32597660;6308621;9169872;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZF0", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation;GO:0000028 ribosomal small subunit assembly", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P02407-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P03874-1", "uniprot_id": [ { "id": "CBP2_YEAST", "url": "https://www.uniprot.org/uniprot/P03874", "type": "external" } ], "mass": 73861.0, "length": 630, "protein_name": "Cytochrome B pre-mRNA-processing protein 2", "gene_name": "CBP2", "organism": "Yeast", "refseq_name": "Cbp2p", "refseq_ac": [ { "id": "NP_011825", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011825", "type": "external" } ], "gene_names_uniprotkb": "CBP2", "gene_names_refseq": "CBP2", "protein_names_uniprotkb": "Cytochrome B pre-mRNA-processing protein 2", "protein_names_refseq": "Cbp2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHL038C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;24374639;32597660;33491328;6348045;8091229;9092668", "class_list": "", "function": "Appears to be specifically required for the splicing of the terminal intron (bI5) of the cytochrome b pre-mRNA. Can also stimulates the splicing of the omega intron of the precursor of large ribosomal RNA., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKT1", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0090615 mitochondrial mRNA processing;GO:0000372 Group I intron splicing", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P03874-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P03875-1", "uniprot_id": [ { "id": "AI1M_YEAST", "url": "https://www.uniprot.org/uniprot/P03875", "type": "external" } ], "mass": 96079.0, "length": 834, "protein_name": "Putative COX1/OXI3 intron 1 protein", "gene_name": "AI1", "organism": "Yeast", "refseq_name": "intron-encoded reverse transcriptase aI1", "refseq_ac": [ { "id": "NP_009310", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009310", "type": "external" } ], "gene_names_uniprotkb": "AI1", "gene_names_refseq": "AI1", "protein_names_uniprotkb": "Putative COX1/OXI3 intron 1 protein", "protein_names_refseq": "intron-encoded reverse transcriptase aI1", "tax_id": 559292, "disease": "", "pathway": " (sce:Q0050)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "24374639;3549452;6254986;9872396", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0A7NYG1;Q9ZZX5", "ec_number_list": [], "go_molecular_function": "GO:0003964 RNA-directed DNA polymerase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006278 RNA-templated DNA biosynthetic process;GO:0006397 mRNA processing;GO:0006315 homing of group II introns", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P03875-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P03876-1", "uniprot_id": [ { "id": "AI2M_YEAST", "url": "https://www.uniprot.org/uniprot/P03876", "type": "external" } ], "mass": 98008.0, "length": 854, "protein_name": "Putative COX1/OXI3 intron 2 protein", "gene_name": "AI2", "organism": "Yeast", "refseq_name": "intron-encoded reverse transcriptase aI2", "refseq_ac": [ { "id": "NP_009309", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009309", "type": "external" } ], "gene_names_uniprotkb": "AI2", "gene_names_refseq": "AI2", "protein_names_uniprotkb": "Putative COX1/OXI3 intron 2 protein", "protein_names_refseq": "intron-encoded reverse transcriptase aI2", "tax_id": 559292, "disease": "", "pathway": " (sce:Q0055)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "18407956;24374639;6254986;9872396", "class_list": "", 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61463.0, "length": 549, "protein_name": "Glucoamylase, intracellular sporulation-specific", "gene_name": "SGA1", "organism": "Yeast", "refseq_name": "glucan 1,4-alpha-glucosidase", "refseq_ac": [ { "id": "NP_012167", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012167", "type": "external" } ], "gene_names_uniprotkb": "SGA1; SGA", "gene_names_refseq": "SGA1", "protein_names_uniprotkb": "Glucoamylase, intracellular sporulation-specific; 1,4-alpha-D-glucan glucohydrolase; 3.2.1.3; Glucan 1,4-alpha-glucosidase", "protein_names_refseq": "glucan 1,4-alpha-glucosidase", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL099W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "24374639;3106330;3141213;9169870", "class_list": "glycogene;glycosylhydrolase", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVI8;Q07070", "ec_number_list": [], "go_molecular_function": "GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004339 glucan 1,4-alpha-glucosidase activity", "go_cellular_component": "GO:0000324 fungal-type vacuole;GO:0005628 prospore membrane", "go_biological_process": "GO:0005980 glycogen catabolic process;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P08019-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.10100", "kg_view_protein": true }, { "uniprot_canonical_ac": "P08459-1", "uniprot_id": [ { "id": "SPS2_YEAST", "url": "https://www.uniprot.org/uniprot/P08459", "type": "external" } ], "mass": 55939.0, "length": 502, "protein_name": "Sporulation-specific protein 2", "gene_name": "SPS2", "organism": "Yeast", "refseq_name": "Sps2p", "refseq_ac": [ { "id": "NP_010810", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010810", "type": "external" } ], "gene_names_uniprotkb": "SPS2; D9719.26", "gene_names_refseq": "SPS2", "protein_names_uniprotkb": "Sporulation-specific protein 2", "protein_names_refseq": "Sps2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR522C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;15590821;24374639;3023934;3302678;7565676;9169867", "class_list": "", "function": "Involved in middle stages of meiosis. Redundant with SPS22 for the organization of the beta-glucan layer of the spore wall., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 7, "predicted_n_glycosites": 7, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "D6VTE2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0030476 ascospore wall assembly", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P08459-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P08468-1", "uniprot_id": [ { "id": "PT111_YEAST", "url": "https://www.uniprot.org/uniprot/P08468", "type": "external" } ], "mass": 94523.0, "length": 800, "protein_name": "Protein PET111, mitochondrial", "gene_name": "PET111", "organism": "Yeast", "refseq_name": "Pet111p", "refseq_ac": [ { "id": "NP_013984", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013984", "type": "external" } ], "gene_names_uniprotkb": "PET111; YM9920.11C", "gene_names_refseq": "PET111", "protein_names_uniprotkb": "Protein PET111, mitochondrial", "protein_names_refseq": "Pet111p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR257C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;17322287;24374639;2823103;33229814;33481703;33491328;9169872", "class_list": "", "function": "Required for translation of the mitochondrial gene for cytochrome c oxidase subunit II (COX2)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W083", "ec_number_list": [], "go_molecular_function": "GO:0045182 translation regulator activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0033617 mitochondrial respiratory chain complex IV assembly;GO:0070131 positive regulation of mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P08468-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P09007-1", "uniprot_id": [ { "id": "SRD1_YEAST", "url": "https://www.uniprot.org/uniprot/P09007", "type": "external" } ], "mass": 25514.0, "length": 221, "protein_name": "Pre-rRNA-processing protein SRD1", "gene_name": "SRD1", "organism": "Yeast", "refseq_name": "Srd1p", "refseq_ac": [ { "id": "NP_009944", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009944", "type": "external" } ], "gene_names_uniprotkb": "SRD1; YCR18C", "gene_names_refseq": "SRD1", "protein_names_uniprotkb": "Pre-rRNA-processing protein SRD1; Suppressor of rRNA-processing defect protein 1", "protein_names_refseq": "Srd1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR018C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;14562106;1574125;21177495;2179050;24374639;2825123;32597660;33481703;8165142", "class_list": "", "function": "Plays a direct or indirect role in pre-rRNA processing., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR26;P09008;Q06989", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P09007-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P09436-1", "uniprot_id": [ { "id": "SYIC_YEAST", "url": "https://www.uniprot.org/uniprot/P09436", "type": "external" } ], "mass": 122984.0, "length": 1072, "protein_name": "Isoleucine--tRNA ligase, cytoplasmic", "gene_name": "ILS1", "organism": "Yeast", "refseq_name": "isoleucine--tRNA ligase ILS1", "refseq_ac": [ { "id": "NP_009477", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009477", "type": "external" } ], "gene_names_uniprotkb": "ILS1; YBL0734", "gene_names_refseq": "ILS1", "protein_names_uniprotkb": "Isoleucine--tRNA ligase, cytoplasmic; 6.1.1.5; IleRS; Isoleucyl-tRNA synthetase", "protein_names_refseq": "isoleucine--tRNA ligase ILS1", "tax_id": 559292, "disease": "", "pathway": " (sce:YBL076C)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "14562106;17563356;18407956;19779198;21126336;22106047;23749301;24374639;2663194;32597660;3311074;33229814;33481703;33491328;7502586;7813418", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 22, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VPS6", "ec_number_list": [ { "id": "6.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.5", "type": "external" } ], "go_molecular_function": "GO:0002161 aminoacyl-tRNA deacylase activity;GO:0004822 isoleucine-tRNA ligase activity;GO:1990825 sequence-specific mRNA binding;GO:0005524 ATP binding;GO:0000049 tRNA binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006428 isoleucyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P09436-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P09932-1", "uniprot_id": [ { "id": "HO_YEAST", "url": "https://www.uniprot.org/uniprot/P09932", "type": "external" } ], "mass": 66089.0, "length": 586, "protein_name": "Homothallic switching endonuclease", "gene_name": "HO", "organism": "Yeast", "refseq_name": "Hop", "refseq_ac": [ { "id": "NP_010054", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010054", "type": "external" } ], "gene_names_uniprotkb": "HO", "gene_names_refseq": "HO", "protein_names_uniprotkb": "Homothallic switching endonuclease; Ho endonuclease", "protein_names_refseq": "Hop", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL227C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10963670;14506225;14562095;18807043;2005783;24374639;3025649;8590483;9169867", "class_list": "", "function": "Initiation of mating type interconversion. This protein is a site-specific endonuclease that cleaves a site in the mat locus on chromosome III. The double-strand break is followed by a unidirectional gene conversion event that replaces the information at the mat locus by information copied from either of the two homologous loci (HMR and HML) that reside at the extremity of the chromosome III. Endonuclease expression takes place in late G1 just before cells enter S phase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRC8;Q12183", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0016787 hydrolase activity;GO:0004519 endonuclease activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0016539 intein-mediated protein splicing;GO:0007533 mating type switching;GO:0007534 gene conversion at mating-type locus", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P09932-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0C271-1", "uniprot_id": [ { "id": "PELS1_YEAST", "url": "https://www.uniprot.org/uniprot/P0C271", "type": "external" } ], "mass": 4622.0, "length": 40, "protein_name": "Peroxisomal LYS1 stabilizing protein 1", "gene_name": "PLS1", "organism": "Yeast", "refseq_name": "Pls1p", "refseq_ac": [ { "id": "NP_878155", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_878155", "type": "external" } ], "gene_names_uniprotkb": "PLS1; YNL097C-A", "gene_names_refseq": "PLS1; YNL097C-A", "protein_names_uniprotkb": "Peroxisomal LYS1 stabilizing protein 1", "protein_names_refseq": "Pls1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL097C-B)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11753363;16273108;24374639;35563734;8701612;9169873", "class_list": "", "function": "Modulates the lysine biosynthesis pathway, possibly by stabilizing the lysine biosynthesis LYS1 protein in lysine-deplete conditions., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W182;Q8TGS3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005782 peroxisomal matrix;GO:0005829 cytosol", "go_biological_process": "GO:1902986 regulation of lysine biosynthetic process via aminoadipic acid", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P0C271-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0C2H7-1", "uniprot_id": [ { "id": "RL27B_YEAST", "url": "https://www.uniprot.org/uniprot/P0C2H7", "type": "external" } ], "mass": 15505.0, "length": 136, "protein_name": "Large ribosomal subunit protein eL27B", "gene_name": "RPL27B", "organism": "Yeast", "refseq_name": "60S ribosomal protein eL27 RPL27B", "refseq_ac": [ { "id": "NP_010759", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010759", "type": "external" } ], "gene_names_uniprotkb": "RPL27B; D8035.14; RPL27", "gene_names_refseq": "RPL27B", "protein_names_uniprotkb": "Large ribosomal subunit protein eL27B; 60S ribosomal protein L27-B", "protein_names_refseq": "60S ribosomal protein eL27 RPL27B", "tax_id": 559292, "disease": "Diamond-Blackfan anemia 16 (Disease Ontology:DOID:0111893)", "pathway": " (sce:YDR471W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562095;14562106;17563356;18407956;19779198;21177495;22096102;23749301;24374639;24524803;9169867;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT95;P38706", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0030687 preribosome, large subunit precursor;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P0C2H7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0C2I4-1", "uniprot_id": [ { "id": "YH11A_YEAST", "url": "https://www.uniprot.org/uniprot/P0C2I4", "type": "external" } ], "mass": 53325.0, "length": 478, "protein_name": "Transposon Ty1-H Gag polyprotein", "gene_name": "TY1A-H", "organism": "Yeast", "refseq_name": "gag protein", "refseq_ac": [ { "id": "NP_036195", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036195", "type": "external" } ], "gene_names_uniprotkb": "TY1A-H; YHR214C-A; YHRCTy1-1 GAG", "gene_names_refseq": "", "protein_names_uniprotkb": "Transposon Ty1-H Gag polyprotein; Gag-p45; Gag-p49; TY1A; TYA; Transposon Ty1 protein A; p54; p58", "protein_names_refseq": "gag protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR214C-C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "16093660;24374639;8091229;9582191", "class_list": "", "function": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D3DLG7", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P0C2I4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0C2I8-1", "uniprot_id": [ { "id": "YL14A_YEAST", "url": "https://www.uniprot.org/uniprot/P0C2I8", "type": "external" } ], "mass": 49003.0, "length": 440, "protein_name": "Transposon Ty1-LR4 Gag polyprotein", "gene_name": "TY1A-LR4", "organism": "Yeast", "refseq_name": "gag protein", "refseq_ac": [ { "id": "NP_058173", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_058173", "type": "external" } ], "gene_names_uniprotkb": "TY1A-LR4; L9672.1; YLRWTy1-4 GAG", "gene_names_refseq": "", "protein_names_uniprotkb": "Transposon Ty1-LR4 Gag polyprotein; Gag-p45; Gag-p49; TY1A; TYA; Transposon Ty1 protein A; p54; p58", "protein_names_refseq": "gag protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR256W-A)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11884596;16093660;24374639;9169871;9582191", "class_list": "", "function": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VYQ3", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P0C2I8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0C2J4-1", "uniprot_id": [ { "id": "YL21A_YEAST", "url": "https://www.uniprot.org/uniprot/P0C2J4", "type": "external" } ], "mass": 49771.0, "length": 438, "protein_name": "Transposon Ty2-LR1 Gag polyprotein", "gene_name": "TY2A-LR1", "organism": "Yeast", "refseq_name": "gag protein", "refseq_ac": [ { "id": "NP_058175", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_058175", "type": "external" } ], "gene_names_uniprotkb": "TY2A-LR1; L9931.7b; YLRWTy2-1 GAG", "gene_names_refseq": "", "protein_names_uniprotkb": "Transposon Ty2-LR1 Gag polyprotein; TY2A; TYA; Transposon Ty2 protein A", "protein_names_refseq": "gag protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR410W-A)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "16093660;24374639;9169871;9582191", "class_list": "", "function": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty2 RNA and initiation of reverse transcription (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ46", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P0C2J4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0CE11-1", "uniprot_id": [ { "id": "GMT2_YEAST", "url": "https://www.uniprot.org/uniprot/P0CE11", "type": "external" } ], "mass": 27688.0, "length": 249, "protein_name": "Probable GDP-mannose transporter 2", "gene_name": "HVG1", "organism": "Yeast", "refseq_name": "putative GDP-mannose transporter", "refseq_ac": [ { "id": "NP_010956", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010956", "type": "external" } ], "gene_names_uniprotkb": "HVG1; YEM9", "gene_names_refseq": "HVG1; YEM9", "protein_names_uniprotkb": "Probable GDP-mannose transporter 2; GMT 2", "protein_names_refseq": "putative GDP-mannose transporter", "tax_id": 559292, "disease": "", "pathway": " (sce:YER039C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "17322287;24374639;9169868;9395539", "class_list": "", "function": "Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D3DLT8;P40027;Q3E844", "ec_number_list": [], "go_molecular_function": "GO:0015297 antiporter activity;GO:0005458 GDP-mannose transmembrane transporter activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005789 endoplasmic reticulum membrane;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:1990570 GDP-mannose transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P0CE11-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0CW41-1", "uniprot_id": [ { "id": "MALX4_YEAST", "url": "https://www.uniprot.org/uniprot/P0CW41", "type": "external" } ], "mass": 68699.0, "length": 589, "protein_name": "Oligo-1,6-glucosidase IMA4", "gene_name": "IMA4", "organism": "Yeast", "refseq_name": "oligo-1,6-glucosidase IMA4", "refseq_ac": [ { "id": "NP_012314", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012314", "type": "external" } ], "gene_names_uniprotkb": "IMA4; FSP2; HRE589; J0218", "gene_names_refseq": "FSP2; IMA4", "protein_names_uniprotkb": "Oligo-1,6-glucosidase IMA4; 3.2.1.10; Alpha-glucosidase; Flocculent-specific protein 2; Isomaltase 4", "protein_names_refseq": "oligo-1,6-glucosidase IMA4", "tax_id": 559292, "disease": "cystinuria (Disease Ontology:DOID:9266)", "pathway": " (sce:YIL172C); (sce:YJL221C); (R-SCE-352230)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "20562106;24374639;7496153;7725802;8641269", "class_list": "glycogene;glycosylhydrolase", "function": "Alpha-glucosidase with broad substrate specificity for alpha-1,4- and alpha-1,6-glucosides. Not required for isomaltose utilization, but overexpression allows the IMA1 null mutant to grow on isomaltose., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 1, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 123, "biomarker_type": "", "glycan_count": 11, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVX6;P40439", "ec_number_list": [ { "id": "3.2.1.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.10", "type": "external" } ], "go_molecular_function": "GO:0004558 alpha-1,4-glucosidase activity;GO:0004556 alpha-amylase activity;GO:0004574 oligo-1,6-glucosidase activity;GO:0004575 sucrose alpha-glucosidase activity;GO:0033934 glucan 1,4-alpha-maltotriohydrolase activity", "go_cellular_component": "", "go_biological_process": "GO:0000025 maltose catabolic process;GO:0005987 sucrose catabolic process;GO:0046352 disaccharide catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P0CW41-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.1000000000000.000.10100", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0CX09-1", "uniprot_id": [ { "id": "MAN2_YEAST", "url": "https://www.uniprot.org/uniprot/P0CX09", "type": "external" } ], "mass": 56470.0, "length": 502, "protein_name": "Mannitol dehydrogenase 2", "gene_name": "MAN2", "organism": "Yeast", "refseq_name": "putative mannitol dehydrogenase", "refseq_ac": [ { "id": "NP_014471", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014471", "type": "external" } ], "gene_names_uniprotkb": "MAN2; N3810", "gene_names_refseq": "MAN2", "protein_names_uniprotkb": "Mannitol dehydrogenase 2; 1.1.1.67", "protein_names_refseq": "putative mannitol dehydrogenase", "tax_id": 559292, "disease": "", "pathway": " (sce:YEL070W); (sce:YNR073C)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "24374639;26996892;8904342;9169873", "class_list": "", "function": "Catalyzes the NAD(H)-dependent interconversion of D-fructose and D-mannitol in the mannitol metabolic pathway., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLI1;P39941", "ec_number_list": [ { "id": "1.1.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.67", "type": "external" } ], "go_molecular_function": "GO:0046029 mannitol dehydrogenase activity;GO:0050086 mannitol 2-dehydrogenase activity", "go_cellular_component": "", "go_biological_process": "GO:0019594 mannitol metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P0CX09-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0CX10-1", "uniprot_id": [ { "id": "ERR1_YEAST", "url": "https://www.uniprot.org/uniprot/P0CX10", "type": "external" } ], "mass": 47328.0, "length": 437, "protein_name": "Enolase-related protein 1", "gene_name": "ERR1", "organism": "Yeast", "refseq_name": "phosphopyruvate hydratase ERR1", "refseq_ac": [ { "id": "NP_015038", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015038", "type": "external" } ], "gene_names_uniprotkb": "ERR1", "gene_names_refseq": "ERR1", "protein_names_uniprotkb": "Enolase-related protein 1; 2-phospho-D-glycerate hydro-lyase; 2-phosphoglycerate dehydratase; 4.2.1.11", "protein_names_refseq": "phosphopyruvate hydratase ERR1", "tax_id": 559292, "disease": "prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); urinary bladder cancer (Disease Ontology:DOID:11054); migraine without aura (Disease Ontology:DOID:12783); aortic valve stenosis (Disease Ontology:DOID:1712); neuroendocrine carcinoma (Disease Ontology:DOID:1800); breast carcinoma (Disease Ontology:DOID:3459); brain disease (Disease Ontology:DOID:936)", "pathway": " (sce:YOR393W); (sce:YPL281C); (R-SCE-70171); (R-SCE-70263)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "24374639;7785338;9169874", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W385;Q12007;Q7LGJ4", "ec_number_list": [ { "id": "4.2.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.11", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004634 phosphopyruvate hydratase activity", "go_cellular_component": "GO:0000015 phosphopyruvate hydratase complex", "go_biological_process": "GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P0CX10-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0CX11-1", "uniprot_id": [ { "id": "ERR2_YEAST", "url": "https://www.uniprot.org/uniprot/P0CX11", "type": "external" } ], "mass": 47328.0, "length": 437, "protein_name": "Enolase-related protein 2", "gene_name": "ERR2", "organism": "Yeast", "refseq_name": "phosphopyruvate hydratase ERR2", "refseq_ac": [ { "id": "NP_015042", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015042", "type": "external" } ], "gene_names_uniprotkb": "ERR2", "gene_names_refseq": "ERR2", "protein_names_uniprotkb": "Enolase-related protein 2; 2-phospho-D-glycerate hydro-lyase; 2-phosphoglycerate dehydratase; 4.2.1.11", "protein_names_refseq": "phosphopyruvate hydratase ERR2", "tax_id": 559292, "disease": "prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); urinary bladder cancer (Disease Ontology:DOID:11054); migraine without aura (Disease Ontology:DOID:12783); aortic valve stenosis (Disease Ontology:DOID:1712); neuroendocrine carcinoma (Disease Ontology:DOID:1800); breast carcinoma (Disease Ontology:DOID:3459); brain disease (Disease Ontology:DOID:936)", "pathway": " (sce:YOR393W); (sce:YPL281C); (R-SCE-70171); (R-SCE-70263)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "24374639;9169875", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W385;Q12007;Q7LGJ4", "ec_number_list": [ { "id": "4.2.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.11", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004634 phosphopyruvate hydratase activity", "go_cellular_component": "GO:0000015 phosphopyruvate hydratase complex", "go_biological_process": "GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P0CX11-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0CX13-1", "uniprot_id": [ { "id": "COS3_YEAST", "url": "https://www.uniprot.org/uniprot/P0CX13", "type": "external" } ], "mass": 45165.0, "length": 379, "protein_name": "Protein COS3", "gene_name": "COS3", "organism": "Yeast", "refseq_name": "Cos3p", "refseq_ac": [ { "id": "NP_013574", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013574", "type": "external" } ], "gene_names_uniprotkb": "COS3; YM4987.03", "gene_names_refseq": "COS3", "protein_names_uniprotkb": "Protein COS3", "protein_names_refseq": "Cos3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR302C); (sce:YML132W)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "16847258;19779198;19795423;19823750;20702584;24374639;9169872", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQU7;P38363", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0006883 intracellular sodium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P0CX13-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0CX22-1", "uniprot_id": [ { "id": "YRF18_YEAST", "url": "https://www.uniprot.org/uniprot/P0CX22", "type": "external" } ], "mass": 203781.0, "length": 1796, "protein_name": "Y' element ATP-dependent helicase protein 1 copy 8", "gene_name": "YRF1-8", "organism": "Yeast", "refseq_name": "Y' element ATP-dependent helicase protein 1 copy 8", "refseq_ac": [ { "id": "NP_061495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_061495", "type": "external" } ], "gene_names_uniprotkb": "YRF1-8; O7535", "gene_names_refseq": "YRF1-8", "protein_names_uniprotkb": "Y' element ATP-dependent helicase protein 1 copy 8; 5.6.2.-", "protein_names_refseq": "Y' element ATP-dependent helicase protein 1 copy 8", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR545W); (sce:YLR467W); (sce:YOR396W)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "1628806;19779198;24374639;7785338;9169874;9837911", "class_list": "", "function": "Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTG2;O94087;P24088;P24089;Q53WX0;Q99313", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003676 nucleic acid binding;GO:0004386 helicase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0000722 telomere maintenance via recombination", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P0CX22-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0CX24-1", "uniprot_id": [ { "id": "RL20B_YEAST", "url": "https://www.uniprot.org/uniprot/P0CX24", "type": "external" } ], "mass": 20437.0, "length": 172, "protein_name": "Large ribosomal subunit protein eL20B", "gene_name": "RPL20B", "organism": "Yeast", "refseq_name": "60S ribosomal protein eL20 RPL20B", "refseq_ac": [ { "id": "NP_014957", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014957", "type": "external" } ], "gene_names_uniprotkb": "RPL20B; O6116; RPL18A1; RPL18B", "gene_names_refseq": "RPL18A1; RPL20B", "protein_names_uniprotkb": "Large ribosomal subunit protein eL20B; 60S ribosomal protein L20-B; L18a", "protein_names_refseq": "60S ribosomal protein eL20 RPL20B", "tax_id": 559292, "disease": "alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (sce:YMR242C); (sce:YOR312C); (R-SCE-156827); (R-SCE-1799339); (R-SCE-72689); (R-SCE-72706); (R-SCE-975956); (R-SCE-975957); (R-SCE-9954709); (R-SCE-9954714)", "pathway_count": 10, "publication_count": 13, "publication_id_list": "14562095;17101987;17287358;17351133;22096102;22106047;22814378;24374639;24524803;33491328;8896266;9169874;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1YV95;A1YV96;D6W068;P0C2I0;P0C2I1;P47913", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P0CX24-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0CX57-1", "uniprot_id": [ { "id": "YA11A_YEAST", "url": "https://www.uniprot.org/uniprot/P0CX57", "type": "external" } ], "mass": 49072.0, "length": 440, "protein_name": "Transposon Ty1-A Gag polyprotein", "gene_name": "TY1A-A", "organism": "Yeast", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TY1A-A; P9659.6d; YARCTy1-1 GAG", "gene_names_refseq": "", "protein_names_uniprotkb": "Transposon Ty1-A Gag polyprotein; Gag-p45; Gag-p49; TY1A; TYA; Transposon Ty1 protein A; p54; p58", "protein_names_refseq": "", "tax_id": 559292, "disease": "", "pathway": " (sce:YAR010C); (sce:YPR137C-A)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "11884596;16093660;24374639;7731988;7941740;9582191", "class_list": "", "function": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VPM2;O13528", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P0CX57-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0CX58-1", "uniprot_id": [ { "id": "YP12A_YEAST", "url": "https://www.uniprot.org/uniprot/P0CX58", "type": "external" } ], "mass": 49072.0, "length": 440, "protein_name": "Transposon Ty1-PR1 Gag polyprotein", "gene_name": "TY1A-PR1", "organism": "Yeast", "refseq_name": "gag protein", "refseq_ac": [ { "id": "NP_009407", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009407", "type": "external" } ], "gene_names_uniprotkb": "TY1A-PR1; P9659.6d; YPRCTy1-2 GAG", "gene_names_refseq": "", "protein_names_uniprotkb": "Transposon Ty1-PR1 Gag polyprotein; Gag-p45; Gag-p49; TY1A; TYA; Transposon Ty1 protein A; p54; p58", "protein_names_refseq": "gag protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YAR010C); (sce:YPR137C-A)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "11884596;16093660;17330950;17563356;18407956;19779198;21177495;24374639;9169875;9582191", "class_list": "", "function": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. 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CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 27, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VPM2;O13528", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P0CX58-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0CX59-1", "uniprot_id": [ { "id": "YO12A_YEAST", "url": "https://www.uniprot.org/uniprot/P0CX59", "type": "external" } ], "mass": 49098.0, "length": 440, "protein_name": "Transposon Ty1-OR Gag polyprotein", "gene_name": "TY1A-OR", "organism": "Yeast", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TY1A-OR; O3364; YORWTy1-2 GAG", "gene_names_refseq": "", "protein_names_uniprotkb": "Transposon Ty1-OR Gag polyprotein; Gag-p45; Gag-p49; TY1A; TYA; Transposon Ty1 protein A; p54; p58", "protein_names_refseq": "", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR142W-A); (sce:YPR158W-A)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "11884596;16093660;24374639;9169874;9582191", "class_list": "", "function": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. 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CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6W2K0;Q99209", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P0CX60-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0CX61-1", "uniprot_id": [ { "id": "YF21A_YEAST", "url": "https://www.uniprot.org/uniprot/P0CX61", "type": "external" } ], "mass": 49762.0, "length": 438, "protein_name": "Transposon Ty2-F Gag polyprotein", "gene_name": "TY2A-F", "organism": "Yeast", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TY2A-F; F006; YFLWTy2-1 GAG", "gene_names_refseq": "", "protein_names_uniprotkb": "Transposon Ty2-F Gag polyprotein; TY2A; TYA; Transposon Ty2 protein A", "protein_names_refseq": "", "tax_id": 559292, "disease": "", "pathway": " (sce:YFL002W-B); (sce:YGR161W-A)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "16093660;24374639;7670463;9582191", "class_list": "", "function": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. 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CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty2 RNA and initiation of reverse transcription (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTM8;Q99195", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P0CX61-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0CX62-1", "uniprot_id": [ { "id": "YG22A_YEAST", "url": "https://www.uniprot.org/uniprot/P0CX62", "type": "external" } ], "mass": 49762.0, "length": 438, "protein_name": "Transposon Ty2-GR2 Gag polyprotein", "gene_name": "TY2A-GR2", "organism": "Yeast", "refseq_name": "gag protein", "refseq_ac": [ { "id": "NP_058157", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_058157", "type": "external" } ], "gene_names_uniprotkb": "TY2A-GR2; G7015; YGRWTy2-2 GAG", "gene_names_refseq": "", "protein_names_uniprotkb": "Transposon Ty2-GR2 Gag polyprotein; TY2A; TYA; Transposon Ty2 protein A", "protein_names_refseq": "gag protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YFL002W-B); (sce:YGR161W-A)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "16093660;24374639;9169869;9582191", "class_list": "", "function": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. 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CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VWK0;P47097;Q66R50", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P0CX75-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0CX76-1", "uniprot_id": [ { "id": "YM12A_YEAST", "url": "https://www.uniprot.org/uniprot/P0CX76", "type": "external" } ], "mass": 48993.0, "length": 440, "protein_name": "Transposon Ty1-ML2 Gag polyprotein", "gene_name": "TY1A-ML2", "organism": "Yeast", "refseq_name": "gag protein", "refseq_ac": [ { "id": "NP_012561", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012561", "type": "external" } ], "gene_names_uniprotkb": "TY1A-ML2; YM8054.03; YMLWTy1-2 GAG", "gene_names_refseq": "", "protein_names_uniprotkb": "Transposon Ty1-ML2 Gag polyprotein; Gag-p45; Gag-p49; TY1A; TYA; Transposon Ty1 protein A; p54; p58", "protein_names_refseq": "gag protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR026W); (sce:YLR227W-A); (sce:YML040W)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "11884596;16093660;17287358;24374639;9169872;9582191", "class_list": "", "function": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VWK0;P47097;Q66R50", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P0CX76-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0CY07-1", "uniprot_id": [ { "id": "HMAL1_YEAST", "url": "https://www.uniprot.org/uniprot/P0CY07", "type": "external" } ], "mass": 20413.0, "length": 175, "protein_name": "Silenced mating-type protein ALPHA1", "gene_name": "HMLALPHA1", "organism": "Yeast", "refseq_name": "transcriptional co-activator mating type protein alpha", "refseq_ac": [ { "id": "NP_009867", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009867", "type": "external" } ], "gene_names_uniprotkb": "HMLALPHA1; YCL66W", "gene_names_refseq": "ALPHA1; HMLALPHA1", "protein_names_uniprotkb": "Silenced mating-type protein ALPHA1; Alpha-1 activator; MATalpha1 protein", "protein_names_refseq": "transcriptional co-activator mating type protein alpha", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL066W); (sce:YCR040W)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "1574125;17322287;24374639;33502312;6256656;6276023;7021055;7034964", "class_list": "", "function": "Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion. Silenced copy of ALPHA1 at HML., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQV3;P01365", "ec_number_list": [], "go_molecular_function": "GO:0008301 DNA binding, bending;GO:0003713 transcription coactivator activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007532 regulation of mating-type specific transcription, DNA-templated;GO:0045895 positive regulation of mating-type specific transcription, DNA-templated", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P0CY07-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0CY09-1", "uniprot_id": [ { "id": "HMAL2_YEAST", "url": "https://www.uniprot.org/uniprot/P0CY09", "type": "external" } ], "mass": 24282.0, "length": 210, "protein_name": "Silenced mating-type protein ALPHA2", "gene_name": "HMLALPHA2", "organism": "Yeast", "refseq_name": "homeodomain mating type protein alpha2", "refseq_ac": [ { "id": "NP_009866", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009866", "type": "external" } ], "gene_names_uniprotkb": "HMLALPHA2; YCL67C", "gene_names_refseq": "ALPHA2; HMLALPHA2", "protein_names_uniprotkb": "Silenced mating-type protein ALPHA2; Alpha-2 repressor; MATalpha2 protein", "protein_names_refseq": "homeodomain mating type protein alpha2", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL067C); (sce:YCR039C)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "1574125;24374639;6256656;6276023;7021055;7034964", "class_list": "", "function": "Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion. Silenced copy of ALPHA2 at HML., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQV2;P01367;P01368;Q6B2C0", "ec_number_list": [], "go_molecular_function": "GO:0008301 DNA binding, bending;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007531 mating type determination", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P0CY09-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0CY11-1", "uniprot_id": [ { "id": "HMRA1_YEAST", "url": "https://www.uniprot.org/uniprot/P0CY11", "type": "external" } ], "mass": 14803.0, "length": 126, "protein_name": "Silenced mating-type protein A1", "gene_name": "HMRA1", "organism": "Yeast", "refseq_name": "Hmra1p", "refseq_ac": [ { "id": "NP_010021", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010021", "type": "external" } ], "gene_names_uniprotkb": "HMRA1; YCR97W", "gene_names_refseq": "HMRA1; YCR097WB", "protein_names_uniprotkb": "Silenced mating-type protein A1; MATa1 protein", "protein_names_refseq": "Hmra1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR097W)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "1574125;1574927;24374639", "class_list": "", "function": "Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion. Silenced copy of A1 at HMR., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR98;P01366;P09091;Q06724", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003714 transcription corepressor activity;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007532 regulation of mating-type specific transcription, DNA-templated", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P0CY11-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P10662-1", "uniprot_id": [ { "id": "RT01_YEAST", "url": "https://www.uniprot.org/uniprot/P10662", "type": "external" } ], "mass": 36729.0, "length": 321, "protein_name": "Small ribosomal subunit protein mS43", "gene_name": "MRP1", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein mS43 MRP1", "refseq_ac": [ { "id": "NP_010634", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010634", "type": "external" } ], "gene_names_uniprotkb": "MRP1; D9651.1", "gene_names_refseq": "MRP1; mS43", "protein_names_uniprotkb": "Small ribosomal subunit protein mS43; 37S ribosomal protein MRP1, mitochondrial", "protein_names_refseq": "mitochondrial 37S ribosomal protein mS43 MRP1", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR347W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "11278769;12392552;12426313;14562095;14562106;14576278;17322287;2185247;24374639;25609543;28154081;3029111;32597660;33481703;33491328;9169867", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSX7", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004784 superoxide dismutase activity;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P10662-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P10663-1", "uniprot_id": [ { "id": "RT02_YEAST", "url": "https://www.uniprot.org/uniprot/P10663", "type": "external" } ], "mass": 13538.0, "length": 115, "protein_name": "Small ribosomal subunit protein uS14m", "gene_name": "MRP2", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein uS14m MRP2", "refseq_ac": [ { "id": "NP_015492", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015492", "type": "external" } ], "gene_names_uniprotkb": "MRP2; P9325.7", "gene_names_refseq": "MRP2; uS14m", "protein_names_uniprotkb": "Small ribosomal subunit protein uS14m; 37S ribosomal protein MRP2, mitochondrial", "protein_names_refseq": "mitochondrial 37S ribosomal protein uS14m MRP2", "tax_id": 559292, "disease": "combined oxidative phosphorylation deficiency 38 (Disease Ontology:DOID:0111466)", "pathway": " (sce:YPR166C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "11278769;12392552;14576278;17322287;24374639;25609543;28154081;3029111;33491328;7770043;9169875", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4G7", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006412 translation;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P10663-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P14127-1", "uniprot_id": [ { "id": "RS17B_YEAST", "url": "https://www.uniprot.org/uniprot/P14127", "type": "external" } ], "mass": 15803.0, "length": 136, "protein_name": "Small ribosomal subunit protein eS17B", "gene_name": "RPS17B", "organism": "Yeast", "refseq_name": "40S ribosomal protein eS17 RPS17B", "refseq_ac": [ { "id": "NP_010735", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010735", "type": "external" } ], "gene_names_uniprotkb": "RPS17B; RP51B", "gene_names_refseq": "RP51B; RPL51B; RPS17B", "protein_names_uniprotkb": "Small ribosomal subunit protein eS17B; 40S ribosomal protein S17-B; RP51B", "protein_names_refseq": "40S ribosomal protein eS17 RPS17B", "tax_id": 559292, "disease": "intrinsic cardiomyopathy (Disease Ontology:DOID:0060036); Diamond-Blackfan anemia 4 (Disease Ontology:DOID:0111890); Diamond-Blackfan anemia (Disease Ontology:DOID:1339)", "pathway": " (sce:YDR447C); (R-SCE-156827); (R-SCE-1799339); (R-SCE-6791226); (R-SCE-72649); (R-SCE-72689); (R-SCE-72695); (R-SCE-72702); (R-SCE-72706); (R-SCE-975956); (R-SCE-975957); (R-SCE-9954714)", "pathway_count": 12, "publication_count": 16, "publication_id_list": "14562095;14562106;15665377;18407956;19779198;19795423;19823750;21177495;22096102;22218487;23749301;24374639;24524803;6092944;9169867;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT72", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation;GO:0000028 ribosomal small subunit assembly", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P14127-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P14905-1", "uniprot_id": [ { "id": "CBP7_YEAST", "url": "https://www.uniprot.org/uniprot/P14905", "type": "external" } ], "mass": 44608.0, "length": 389, "protein_name": "Cytochrome B translational activator CBS2", "gene_name": "CBS2", "organism": "Yeast", "refseq_name": "Cbs2p", "refseq_ac": [ { "id": "NP_010483", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010483", "type": "external" } ], "gene_names_uniprotkb": "CBS2; CBP7; YD9346.08", "gene_names_refseq": "CBP7; CBS2", "protein_names_uniprotkb": "Cytochrome B translational activator CBS2", "protein_names_refseq": "Cbs2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR197W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;17322287;2270079;24374639;3070350;9169867", "class_list": "", "function": "Translational activator of cytochrome b. The cytochrome b (coB) leader RNA may represent the target sequence for CBS1 and/ or CBS2., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSI0", "ec_number_list": [], "go_molecular_function": "GO:0045182 translation regulator activity;GO:0050661 NADP binding;GO:0008677 2-dehydropantoate 2-reductase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005761 mitochondrial ribosome", "go_biological_process": "GO:0070131 positive regulation of mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P14905-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P16120-1", "uniprot_id": [ { "id": "THRC_YEAST", "url": "https://www.uniprot.org/uniprot/P16120", "type": "external" } ], "mass": 57474.0, "length": 514, "protein_name": "Threonine synthase", "gene_name": "THR4", "organism": "Yeast", "refseq_name": "threonine synthase THR4", "refseq_ac": [ { "id": "NP_009982", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009982", "type": "external" } ], "gene_names_uniprotkb": "THR4; YCR53W", "gene_names_refseq": "THR4", "protein_names_uniprotkb": "Threonine synthase; 4.2.3.1; TS", "protein_names_refseq": "threonine synthase THR4", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR053W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "11756443;14562106;1574125;17322287;18407956;19779198;20305002;20305003;21126336;2204248;22814378;23749301;2408022;24374639;33481703;33491328;8082795", "class_list": "", "function": "Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR61;E9P943", "ec_number_list": [ { "id": "4.2.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.3.1", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004795 threonine synthase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0009088 threonine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P16120-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P16151-1", "uniprot_id": [ { "id": "ERD1_YEAST", "url": "https://www.uniprot.org/uniprot/P16151", "type": "external" } ], "mass": 43230.0, "length": 362, "protein_name": "Protein ERD1", "gene_name": "ERD1", "organism": "Yeast", "refseq_name": "Erd1p", "refseq_ac": [ { "id": "NP_010702", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010702", "type": "external" } ], "gene_names_uniprotkb": "ERD1; D9461.4", "gene_names_refseq": "ERD1; LDB2", "protein_names_uniprotkb": "Protein ERD1", "protein_names_refseq": "Erd1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR414C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "16847258;2178921;24374639;9169867", "class_list": "", "function": "Required for the retention of luminal endoplasmic reticulum proteins, affects glycoprotein processing in the Golgi apparatus., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT45", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0015031 protein transport;GO:0009101 glycoprotein biosynthetic process;GO:0006621 protein retention in ER lumen;GO:0000301 retrograde transport, vesicle recycling within Golgi", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P16151-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P16523-1", "uniprot_id": [ { "id": "MER1_YEAST", "url": "https://www.uniprot.org/uniprot/P16523", "type": "external" } ], "mass": 31111.0, "length": 270, "protein_name": "Meiotic recombination 1 protein", "gene_name": "MER1", "organism": "Yeast", "refseq_name": "Mer1p", "refseq_ac": [ { "id": "NP_014189", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014189", "type": "external" } ], "gene_names_uniprotkb": "MER1; N1330", "gene_names_refseq": "MER1", "protein_names_uniprotkb": "Meiotic recombination 1 protein", "protein_names_refseq": "Mer1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL210W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "17322287;2183032;24374639;7762305;9169873", "class_list": "", "function": "Required for chromosome pairing and genetic recombination. MER1 may function to bring the axial elements of the synaptonemal complex corresponding to homologous chromosomes together by initiating recombination. MER1 might be responsible for regulating the MER2 gene and/or gene product., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0Y0", "ec_number_list": [], "go_molecular_function": "GO:1990446 U1 snRNP binding;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0048026 positive regulation of mRNA splicing, via spliceosome;GO:0007131 reciprocal meiotic recombination", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P16523-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P16547-1", "uniprot_id": [ { "id": "OM45_YEAST", "url": "https://www.uniprot.org/uniprot/P16547", "type": "external" } ], "mass": 44580.0, "length": 393, "protein_name": "Mitochondrial outer membrane protein OM45", "gene_name": "OM45", "organism": "Yeast", "refseq_name": "Om45p", "refseq_ac": [ { "id": "NP_012130", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012130", "type": "external" } ], "gene_names_uniprotkb": "OM45", "gene_names_refseq": "OM45", "protein_names_uniprotkb": "Mitochondrial outer membrane protein OM45; Outer membrane protein of 45 kDa", "protein_names_refseq": "Om45p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL136W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "11502169;14562106;17322287;18407956;21126336;21177495;21987634;23749301;24374639;2687271;33491328;9169870", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVF0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P16547-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P16639-1", "uniprot_id": [ { "id": "ATE1_YEAST", "url": "https://www.uniprot.org/uniprot/P16639", "type": "external" } ], "mass": 57930.0, "length": 503, "protein_name": "Arginyl-tRNA--protein transferase 1", "gene_name": "ATE1", "organism": "Yeast", "refseq_name": "arginyltransferase", "refseq_ac": [ { "id": "NP_011498", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011498", "type": "external" } ], "gene_names_uniprotkb": "ATE1", "gene_names_refseq": "ATE1", "protein_names_uniprotkb": "Arginyl-tRNA--protein transferase 1; 2.3.2.8; Arginine-tRNA--protein transferase 1; Arginyltransferase 1; R-transferase 1", "protein_names_refseq": "arginyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL017W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;1882553;2185248;24374639;33491328;9169869", "class_list": "", "function": "Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway (PubMed:2185248). Does not arginylate cysteine residues (By similarity)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUC0", "ec_number_list": [ { "id": "2.3.2.8", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.8", "type": "external" } ], "go_molecular_function": "GO:0004057 arginyl-tRNA--protein transferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006915 apoptotic process;GO:0010498 proteasomal protein catabolic process;GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P16639-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P16965-1", "uniprot_id": [ { "id": "STF2_YEAST", "url": "https://www.uniprot.org/uniprot/P16965", "type": "external" } ], "mass": 9615.0, "length": 84, "protein_name": "ATPase-stabilizing factor 15 kDa protein", "gene_name": "STF2", "organism": "Yeast", "refseq_name": "ATPase-stabilizing factor family protein", "refseq_ac": [ { "id": "NP_011522", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011522", "type": "external" } ], "gene_names_uniprotkb": "STF2; G3858", "gene_names_refseq": "STF2", "protein_names_uniprotkb": "ATPase-stabilizing factor 15 kDa protein; 15 kDa ATPase inhibitor complex-stabilizing factor; 15K; Hydrophilin STF2; Stabilizing factor 2", "protein_names_refseq": "ATPase-stabilizing factor family protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR008C)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "11875433;14562106;17287358;17322287;17563356;18407956;19684113;19779198;19795423;19823750;21177495;2169416;2172220;22218487;22442684;24374639;32597660;33481703;33491328;6200468;8982874;9169869", "class_list": "", "function": "Found to stabilize, together with STF1, a complex of intrinsic ATPase inhibitor INH1 and proton-translocating ATPase (F(1)F(0)-ATPase) in mitochondrial membranes (PubMed:6200468). Binds to the F0 part and may function to hold the ATPase inhibitor or STF1 on the F1 subunit (PubMed:2172220). Also acts as a hydrophilins that enhances dry stress tolerance. Cell viability after desiccation and rehydration is due to the antioxidant capacity of the protein, which reduces the number of apoptotic cells during stress conditions by minimising the accumulation of reactive oxygen species (ROS) in the cells (PubMed:22442684)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUE5;P89099", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0071465 cellular response to desiccation", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P16965-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P17122-1", "uniprot_id": [ { "id": "SPO16_YEAST", "url": "https://www.uniprot.org/uniprot/P17122", "type": "external" } ], "mass": 23131.0, "length": 198, "protein_name": "Sporulation-specific protein 16", "gene_name": "SPO16", "organism": "Yeast", "refseq_name": "Spo16p", "refseq_ac": [ { "id": "NP_012023", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012023", "type": "external" } ], "gene_names_uniprotkb": "SPO16", "gene_names_refseq": "SPO16", "protein_names_uniprotkb": "Sporulation-specific protein 16", "protein_names_refseq": "Spo16p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR153C)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "2188099;24374639;8091229", "class_list": "", "function": "Necessary for efficient spore formation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLA2", "ec_number_list": [], "go_molecular_function": "GO:0000217 DNA secondary structure binding", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0000228 nuclear chromosome", "go_biological_process": "GO:0016925 protein sumoylation;GO:0007130 synaptonemal complex assembly;GO:0033235 positive regulation of protein sumoylation;GO:0007129 homologous chromosome pairing at meiosis;GO:0007131 reciprocal meiotic recombination", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P17122-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P17123-1", "uniprot_id": [ { "id": "SPO12_YEAST", "url": "https://www.uniprot.org/uniprot/P17123", "type": "external" } ], "mass": 19912.0, "length": 173, "protein_name": "Sporulation-specific protein 12", "gene_name": "SPO12", "organism": "Yeast", "refseq_name": "Spo12p", "refseq_ac": [ { "id": "NP_012022", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012022", "type": "external" } ], "gene_names_uniprotkb": "SPO12", "gene_names_refseq": "SDB21; SPO12", "protein_names_uniprotkb": "Sporulation-specific protein 12", "protein_names_refseq": "Spo12p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR152W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "11832211;14562106;19268588;19684113;19779198;21177495;2188099;22814378;23749301;24374639;32597660;33481703;33491328;8091229", "class_list": "", "function": "It is required for meiosis I chromosome division during sporulation. A component of the FEAR (CDC14 early anaphase release) network which promotes CDC14 release from the nucleolus during early anaphase., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLA1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus", "go_biological_process": "GO:1904750 negative regulation of protein localization to nucleolus;GO:0031536 positive regulation of exit from mitosis;GO:0007127 meiosis I;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P17123-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P17558-1", "uniprot_id": [ { "id": "RTPT_YEAST", "url": "https://www.uniprot.org/uniprot/P17558", "type": "external" } ], "mass": 35998.0, "length": 318, "protein_name": "Small ribosomal subunit protein mS26", "gene_name": "PET123", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein mS26 PET123", "refseq_ac": [ { "id": "NP_014801", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014801", "type": "external" } ], "gene_names_uniprotkb": "PET123", "gene_names_refseq": "PET123; mS26", "protein_names_uniprotkb": "Small ribosomal subunit protein mS26; 37S ribosomal protein PET123, mitochondrial", "protein_names_refseq": "mitochondrial 37S ribosomal protein mS26 PET123", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR158W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "11278769;12392552;14562095;14562106;14576278;1696234;2167435;22814378;23749301;24374639;25609543;28154081;32597660;33491328;9046089;9169874", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2L5", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P17558-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P18411-1", "uniprot_id": [ { "id": "FUN14_YEAST", "url": "https://www.uniprot.org/uniprot/P18411", "type": "external" } ], "mass": 22063.0, "length": 198, "protein_name": "Protein FUN14", "gene_name": "FUN14", "organism": "Yeast", "refseq_name": "Fun14p", "refseq_ac": [ { "id": "NP_009394", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009394", "type": "external" } ], "gene_names_uniprotkb": "FUN14", "gene_names_refseq": "FUN14; MCP3", "protein_names_uniprotkb": "Protein FUN14", "protein_names_refseq": "Fun14p", "tax_id": 559292, "disease": "", "pathway": " (sce:YAL008W); (R-SCE-8934903)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "14562106;17322287;2253888;24374639;7731988;7941740", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPL0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0055091 phospholipid homeostasis;GO:0007005 mitochondrion organization;GO:0000422 autophagy of mitochondrion", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P18411-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P18496-1", "uniprot_id": [ { "id": "ATP10_YEAST", "url": "https://www.uniprot.org/uniprot/P18496", "type": "external" } ], "mass": 32094.0, "length": 279, "protein_name": "Mitochondrial ATPase complex subunit ATP10", "gene_name": "ATP10", "organism": "Yeast", "refseq_name": "Atp10p", "refseq_ac": [ { "id": "NP_013497", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013497", "type": "external" } ], "gene_names_uniprotkb": "ATP10; L8084.8", "gene_names_refseq": "ATP10", "protein_names_uniprotkb": "Mitochondrial ATPase complex subunit ATP10", "protein_names_refseq": "Atp10p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR393W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;17322287;2141026;24374639;9169871", "class_list": "", "function": "Essential for the assembly of the mitochondrial F1-F0 complex., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ28;Q06020", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P18496-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P18962-1", "uniprot_id": [ { "id": "DAP2_YEAST", "url": "https://www.uniprot.org/uniprot/P18962", "type": "external" } ], "mass": 93404.0, "length": 818, "protein_name": "Dipeptidyl aminopeptidase B", "gene_name": "DAP2", "organism": "Yeast", "refseq_name": "dipeptidyl aminopeptidase", "refseq_ac": [ { "id": "NP_011893", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011893", "type": "external" } ], "gene_names_uniprotkb": "DAP2", "gene_names_refseq": "DAP2; DPP2", "protein_names_uniprotkb": "Dipeptidyl aminopeptidase B; 3.4.14.-; DPAP B; YSCV", "protein_names_refseq": "dipeptidyl aminopeptidase", "tax_id": 559292, "disease": "Middle East respiratory syndrome (Disease Ontology:DOID:0080642); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (sce:YHR028C); (R-SCE-381771)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "17322287;22814378;24374639;2647766;8091229", "class_list": "", "function": "", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D3DKX5;E9P957", "ec_number_list": [ { "id": "3.4.14.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.14.-", "type": "external" } ], "go_molecular_function": "GO:0008239 dipeptidyl-peptidase activity;GO:0004252 serine-type endopeptidase activity;GO:0004177 aminopeptidase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0016485 protein processing", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P18962-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P19956-1", "uniprot_id": [ { "id": "RM44_YEAST", "url": "https://www.uniprot.org/uniprot/P19956", "type": "external" } ], "mass": 11476.0, "length": 98, "protein_name": "Large ribosomal subunit protein mL53", "gene_name": "MRPL44", "organism": "Yeast", "refseq_name": "mitochondrial 54S ribosomal protein mL53 MRPL44", "refseq_ac": [ { "id": "NP_013952", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013952", "type": "external" } ], "gene_names_uniprotkb": "MRPL44; YM9959.07C; YMR44", "gene_names_refseq": "MRPL44; YMR44; mL53", "protein_names_uniprotkb": "Large ribosomal subunit protein mL53; 54S ribosomal protein L44, mitochondrial; YmL44", "protein_names_refseq": "mitochondrial 54S ribosomal protein mL53 MRPL44", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR225C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;14576278;2060626;24374639;24675956;25609543;2693936;9169872", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W050", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P19956-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P20049-1", "uniprot_id": [ { "id": "TYR1_YEAST", "url": "https://www.uniprot.org/uniprot/P20049", "type": "external" } ], "mass": 50923.0, "length": 452, "protein_name": "Prephenate dehydrogenase [NADP(+)]", "gene_name": "TYR1", "organism": "Yeast", "refseq_name": "prephenate dehydrogenase (NADP(+))", "refseq_ac": [ { "id": "NP_009725", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009725", "type": "external" } ], "gene_names_uniprotkb": "TYR1; YBR1218", "gene_names_refseq": "TYR1", "protein_names_uniprotkb": "Prephenate dehydrogenase [NADP(+)]; 1.3.1.13; PRDH", "protein_names_refseq": "prephenate dehydrogenase (NADP(+))", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR166C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;24374639;2697638;33491328;7813418", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQG2", "ec_number_list": [ { "id": "1.3.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.13", "type": "external" } ], "go_molecular_function": "GO:0070403 NAD+ binding;GO:0050661 NADP binding;GO:0004665 prephenate dehydrogenase (NADP+) activity;GO:0008977 prephenate dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006571 tyrosine biosynthetic process;GO:0006570 tyrosine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P20049-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P21264-1", "uniprot_id": [ { "id": "PUR6_YEAST", "url": "https://www.uniprot.org/uniprot/P21264", "type": "external" } ], "mass": 62339.0, "length": 571, "protein_name": "Phosphoribosylaminoimidazole carboxylase", "gene_name": "ADE2", "organism": "Yeast", "refseq_name": "phosphoribosylaminoimidazole carboxylase ADE2", "refseq_ac": [ { "id": "NP_014771", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014771", "type": "external" } ], "gene_names_uniprotkb": "ADE2; O3293; YOR3293C", "gene_names_refseq": "ADE2", "protein_names_uniprotkb": "Phosphoribosylaminoimidazole carboxylase; 4.1.1.21; AIR carboxylase; AIRC", "protein_names_refseq": "phosphoribosylaminoimidazole carboxylase ADE2", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR128C)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "14562106;1514324;19779198;19795423;19823750;21126336;2253890;24374639;32597660;33481703;33491328;8904341;9169874;9200815", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W2I6", "ec_number_list": [ { "id": "4.1.1.21", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.21", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004638 phosphoribosylaminoimidazole carboxylase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006144 purine nucleobase metabolic process;GO:0006189 'de novo' IMP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P21264-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P21592-1", "uniprot_id": [ { "id": "COX10_YEAST", "url": "https://www.uniprot.org/uniprot/P21592", "type": "external" } ], "mass": 52148.0, "length": 462, "protein_name": "Protoheme IX farnesyltransferase, mitochondrial", "gene_name": "COX10", "organism": "Yeast", "refseq_name": "protoheme IX farnesyltransferase", "refseq_ac": [ { "id": "NP_015153", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015153", "type": "external" } ], "gene_names_uniprotkb": "COX10", "gene_names_refseq": "COX10", "protein_names_uniprotkb": "Protoheme IX farnesyltransferase, mitochondrial; 2.5.1.141; HOS; Heme O synthase", "protein_names_refseq": "protoheme IX farnesyltransferase", "tax_id": 559292, "disease": "mitochondrial complex IV deficiency nuclear type 3 (Disease Ontology:DOID:0070492); Parkinson's disease (Disease Ontology:DOID:14330); Leigh disease (Disease Ontology:DOID:3652); cytochrome-c oxidase deficiency disease (Disease Ontology:DOID:3762); mitochondrial myopathy (Disease Ontology:DOID:699)", "pathway": " (sce:YPL172C); (R-SCE-189451)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "11959116;14576278;16823961;18953022;19841065;2167310;22669974;24374639;7836424;8118433;9169875", "class_list": "", "function": "Catalyzes the first reaction in the biosynthesis of heme A, a prosthetic group of mitochondrial cytochrome c oxidase (CcO). Heme A is synthesized from heme B by two sequential enzymatic reactions catalyzed by heme O synthase (HOS/COX10) and heme A synthase (HAS/COX15). HOS converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W3J6", "ec_number_list": [ { "id": "2.5.1.141", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.141", "type": "external" } ], "go_molecular_function": "GO:0008495 protoheme IX farnesyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0006784 heme A biosynthetic process;GO:0048034 heme O biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P21592-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P21705-1", "uniprot_id": [ { "id": "DAL82_YEAST", "url": "https://www.uniprot.org/uniprot/P21705", "type": "external" } ], "mass": 29079.0, "length": 255, "protein_name": "Protein DAL82", "gene_name": "DAL82", "organism": "Yeast", "refseq_name": "Dal82p", "refseq_ac": [ { "id": "NP_014085", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014085", "type": "external" } ], "gene_names_uniprotkb": "DAL82; DURM; N0360", "gene_names_refseq": "DAL82", "protein_names_uniprotkb": "Protein DAL82", "protein_names_refseq": "Dal82p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL314W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "1532796;18407956;1898922;2263474;23749301;24374639;33491328;7502583;9169873", "class_list": "", "function": "Positive regulator of allophanate-induced genes in S.cerevisiae., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, 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binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0000256 allantoin catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P21705-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P22023-1", "uniprot_id": [ { "id": "KRE5_YEAST", "url": "https://www.uniprot.org/uniprot/P22023", "type": "external" } ], "mass": 156477.0, "length": 1365, "protein_name": "Killer toxin-resistance protein 5", "gene_name": "KRE5", "organism": "Yeast", "refseq_name": "Kre5p", "refseq_ac": [ { "id": "NP_014981", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014981", "type": "external" } ], "gene_names_uniprotkb": "KRE5", "gene_names_refseq": "KRE5", "protein_names_uniprotkb": "Killer toxin-resistance protein 5", "protein_names_refseq": "Kre5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR336W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;19684113;2188106;24374639;8896263;9169874", "class_list": "", "function": "Required for (1->6)-beta-D-glucan synthesis and normal cell growth., [UniProtKB]", "predicted_glycosites": 11, "predicted_n_glycosites": 11, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 11, "binding_glycan_count": 0, "secondary_ac_list": "D6W331;Q12190", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0070880 fungal-type cell wall beta-glucan biosynthetic process;GO:0071555 cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P22023-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P22215-1", "uniprot_id": [ { "id": "SLY41_YEAST", "url": "https://www.uniprot.org/uniprot/P22215", "type": "external" } ], "mass": 50903.0, "length": 453, "protein_name": "Uncharacterized transporter SLY41", "gene_name": "SLY41", "organism": "Yeast", "refseq_name": "Sly41p", "refseq_ac": [ { "id": "NP_014952", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014952", "type": "external" } ], "gene_names_uniprotkb": "SLY41; O5663", "gene_names_refseq": "SLY41", "protein_names_uniprotkb": "Uncharacterized transporter SLY41", "protein_names_refseq": "Sly41p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR307C)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "14562106;16847258;17330950;18407956;19779198;19795423;19823750;1990290;21126336;22814378;23749301;24374639;32597660;33481703;33491328;8896266;9153758;9169874", "class_list": "", "function": "Able to suppress the functional loss of YPT1. May form a channel. Protein SLY41 is not essential for cell viability. The SLY41 gene is a multicopy suppressor., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W307", "ec_number_list": [], "go_molecular_function": "GO:0015297 antiporter activity;GO:0089721 phosphoenolpyruvate transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016020 membrane", "go_biological_process": "GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:1990536 phosphoenolpyruvate transmembrane import into Golgi lumen", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P22215-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P22434-1", "uniprot_id": [ { "id": "PDE1_YEAST", "url": "https://www.uniprot.org/uniprot/P22434", "type": "external" } ], "mass": 42016.0, "length": 369, "protein_name": "3',5'-cyclic-nucleotide phosphodiesterase 1", "gene_name": "PDE1", "organism": "Yeast", "refseq_name": "3',5'-cyclic-nucleotide phosphodiesterase PDE1", "refseq_ac": [ { "id": "NP_011266", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011266", "type": "external" } ], "gene_names_uniprotkb": "PDE1; NRB369", "gene_names_refseq": "PDE1", "protein_names_uniprotkb": "3',5'-cyclic-nucleotide phosphodiesterase 1; 3':5'-CNP; 3.1.4.17; Low-affinity cAMP phosphodiesterase; PDEase 1", "protein_names_refseq": "3',5'-cyclic-nucleotide phosphodiesterase PDE1", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL248W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;18407956;24374639;2824992;33491328;8972578;9169869;9880329", "class_list": "", "function": "Controls the level of cAMP in yeast cells, together with the high-affinity cAMP phosphodiesterase (PDE2)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV87", "ec_number_list": [ { "id": "3.1.4.17", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.17", "type": "external" } ], "go_molecular_function": "GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity;GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity", "go_cellular_component": "", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0006198 cAMP catabolic process;GO:1902660 negative regulation of glucose mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P22434-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P23250-1", "uniprot_id": [ { "id": "RPI1_YEAST", "url": "https://www.uniprot.org/uniprot/P23250", "type": "external" } ], "mass": 46623.0, "length": 407, "protein_name": "Negative RAS protein regulator protein", "gene_name": "RPI1", "organism": "Yeast", "refseq_name": "Rpi1p", "refseq_ac": [ { "id": "NP_012147", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012147", "type": "external" } ], "gene_names_uniprotkb": "RPI1", "gene_names_refseq": "RPI1", "protein_names_uniprotkb": "Negative RAS protein regulator protein", "protein_names_refseq": "Rpi1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL119C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562106;1649384;17322287;19779198;19795423;19823750;24374639;33481703;33491328;9169870", "class_list": "", "function": "Negative regulator of the Ras-cyclic AMP pathway. Negatively regulate the activity of normal but not mutationally activated Ras proteins. The down-regulatory effect of RPI1 requires the presence of one of the two Ras GTPase activators, IRA1 and IRA2., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVG8;E9P8U9", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0030695 GTPase regulator activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007265 Ras protein signal transduction;GO:0009272 fungal-type cell wall biogenesis", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P23250-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P23796-1", "uniprot_id": [ { "id": "RIT1_YEAST", "url": "https://www.uniprot.org/uniprot/P23796", "type": "external" } ], "mass": 58882.0, "length": 513, "protein_name": "tRNA A64-2'-O-ribosylphosphate transferase", "gene_name": "RIT1", "organism": "Yeast", "refseq_name": "tRNA A64-2'-O-ribosylphosphate transferase", "refseq_ac": [ { "id": "NP_014010", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014010", "type": "external" } ], "gene_names_uniprotkb": "RIT1; YM8021.09C", "gene_names_refseq": "RIT1", "protein_names_uniprotkb": "tRNA A64-2'-O-ribosylphosphate transferase; 2.4.2.-; Initiator tRNA phosphoribosyl-transferase", "protein_names_refseq": "tRNA A64-2'-O-ribosylphosphate transferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR283C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562106;1718609;17322287;19795423;19823750;24374639;33491328;7954819;9169872", "class_list": "", "function": "tRNA backbone modifying enzyme that mediates initiator/ elongator tRNA discrimination. This enzyme modifies exclusively the initiator tRNA in position 64 using 5'-phosphoribosyl-1'-pyrophosphate as the modification donor. Recognize the stem-loop IV region that is unique in eukaryotic cytoplasmic initiator tRNAs., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0B0", "ec_number_list": [], "go_molecular_function": "GO:0016763 pentosyltransferase activity;GO:0043399 tRNA adenosine(64)-2'-O-ribosylphosphate transferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0019988 charged-tRNA amino acid modification", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P23796-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P23797-1", "uniprot_id": [ { "id": "GPI12_YEAST", "url": "https://www.uniprot.org/uniprot/P23797", "type": "external" } ], "mass": 35446.0, "length": 304, "protein_name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "gene_name": "GPI12", "organism": "Yeast", "refseq_name": "N-acetylglucosaminylphosphatidylinositol deacetylase", "refseq_ac": [ { "id": "NP_014008", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014008", "type": "external" } ], "gene_names_uniprotkb": "GPI12; YM8021.07", "gene_names_refseq": "GPI12", "protein_names_uniprotkb": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; 3.5.1.89", "protein_names_refseq": "N-acetylglucosaminylphosphatidylinositol deacetylase", "tax_id": 559292, "disease": "CHIME syndrome (Disease Ontology:DOID:0112152)", "pathway": " (sce:YMR281W); (R-SCE-162710)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10085243;1718609;21177495;24374639;26928762;9169872", "class_list": "", "function": "Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0A8", "ec_number_list": [ { "id": "3.5.1.89", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.89", "type": "external" } ], "go_molecular_function": "GO:0000225 N-acetylglucosaminylphosphatidylinositol deacetylase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006506 GPI anchor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P23797-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P24031-1", "uniprot_id": [ { "id": "PPA3_YEAST", "url": "https://www.uniprot.org/uniprot/P24031", "type": "external" } ], "mass": 52777.0, "length": 467, "protein_name": "Constitutive acid phosphatase", "gene_name": "PHO3", "organism": "Yeast", "refseq_name": "acid phosphatase PHO3", "refseq_ac": [ { "id": "NP_009650", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009650", "type": "external" } ], "gene_names_uniprotkb": "PHO3; YBR0813", "gene_names_refseq": "PHO3", "protein_names_uniprotkb": "Constitutive acid phosphatase; 3.1.3.2", "protein_names_refseq": "acid phosphatase PHO3", "tax_id": 559292, "disease": "pontocerebellar hypoplasia type 16 (Disease Ontology:DOID:0112333); papillary thyroid carcinoma (Disease Ontology:DOID:3969)", "pathway": " (sce:YBR092C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;19795423;19823750;24374639;6093051;7813418;7900426", "class_list": "", "function": "", "predicted_glycosites": 12, "predicted_n_glycosites": 12, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 12, "binding_glycan_count": 0, "secondary_ac_list": "D6VQ93", "ec_number_list": [ { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.1.3.54", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.54", "type": "external" }, { "id": "3.1.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.7.6", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" } ], "go_molecular_function": "GO:0003993 acid phosphatase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0009277 fungal-type cell wall;GO:0030287 cell wall-bounded periplasmic space", "go_biological_process": "GO:0006796 phosphate-containing compound metabolic process;GO:0042723 thiamine-containing compound metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P24031-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P24720-1", "uniprot_id": [ { "id": "MNE1_YEAST", "url": "https://www.uniprot.org/uniprot/P24720", "type": "external" } ], "mass": 77230.0, "length": 663, "protein_name": "Protein MNE1", "gene_name": "MNE1", "organism": "Yeast", "refseq_name": "Mne1p", "refseq_ac": [ { "id": "NP_014995", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014995", "type": "external" } ], "gene_names_uniprotkb": "MNE1; MNE; O6353", "gene_names_refseq": "MNE1", "protein_names_uniprotkb": "Protein MNE1", "protein_names_refseq": "Mne1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR350C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;1741279;24374639;33491328;8948102;9169874", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W345", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0090615 mitochondrial mRNA processing;GO:0000372 Group I intron splicing", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P24720-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25036-1", "uniprot_id": [ { "id": "YSP3_YEAST", "url": "https://www.uniprot.org/uniprot/P25036", "type": "external" } ], "mass": 52089.0, "length": 478, "protein_name": "Subtilisin-like protease 3", "gene_name": "YSP3", "organism": "Yeast", "refseq_name": "putative subtilisin-like protease YSP3", "refseq_ac": [ { "id": "NP_014645", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014645", "type": "external" } ], "gene_names_uniprotkb": "YSP3", "gene_names_refseq": "YSP3", "protein_names_uniprotkb": "Subtilisin-like protease 3; 3.4.21.-; Subtilisin-like protease III", "protein_names_refseq": "putative subtilisin-like protease YSP3", "tax_id": 559292, "disease": "familial hypercholesterolemia (Disease Ontology:DOID:13810); hypobetalipoproteinemia (Disease Ontology:DOID:1390)", "pathway": " (sce:YOR003W); (R-SCE-8866427); (R-SCE-8964038)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "11115118;24374639;33491328;8896276;9169874;9784122", "class_list": "", "function": "Serine protease with unknown substrate., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W269", "ec_number_list": [ { "id": "3.4.21.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.48", "type": "external" }, { "id": "3.4.21.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.-", "type": "external" } ], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0000328 fungal-type vacuole lumen", "go_biological_process": "GO:0006508 proteolysis;GO:0007039 protein catabolic process in the vacuole;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P25036-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25040-1", "uniprot_id": [ { "id": "TSR4_YEAST", "url": "https://www.uniprot.org/uniprot/P25040", "type": "external" } ], "mass": 45994.0, "length": 408, "protein_name": "uS5 assembly chaperone", "gene_name": "TSR4", "organism": "Yeast", "refseq_name": "small subunit rRNA maturation protein TSR4", "refseq_ac": [ { "id": "NP_014620", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014620", "type": "external" } ], "gene_names_uniprotkb": "TSR4", "gene_names_refseq": "TSR4", "protein_names_uniprotkb": "uS5 assembly chaperone; 20S rRNA accumulation protein 4", "protein_names_refseq": "small subunit rRNA maturation protein TSR4", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL022C)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "14562095;14562106;17287358;17322287;18407956;1935960;19779198;19795423;19806183;19823750;23749301;24374639;31062022;32597660;33481703;33491328;9169874", "class_list": "", "function": "Cytoplasmic chaperone for ribosomal protein uS5; cotranslationally associates with uS5 to facilitate its expression and solubility and is released prior to nuclear import of uS5 (PubMed:31062022). Required for processing of the 20S pre-rRNA at site D to generate mature 18S rRNA (PubMed:19806183)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W243", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0140597 protein carrier chaperone", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0042274 ribosomal small subunit biogenesis;GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P25040-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25335-1", "uniprot_id": [ { "id": "ALLC_YEAST", "url": "https://www.uniprot.org/uniprot/P25335", "type": "external" } ], "mass": 38714.0, "length": 343, "protein_name": "Allantoicase", "gene_name": "DAL2", "organism": "Yeast", "refseq_name": "allantoicase", "refseq_ac": [ { "id": "NP_012295", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012295", "type": "external" } ], "gene_names_uniprotkb": "DAL2; 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YCR045; YCR7C", "gene_names_refseq": "DFP3", "protein_names_uniprotkb": "DUP240 protein DFP3", "protein_names_refseq": "DUP240 family protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR007C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "11283351;12101299;15087486;1574125;1580102;16847258;17322287;24374639;33491328", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR16;Q70DH1;Q70DH4;Q70DH6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P25354-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25355-1", "uniprot_id": [ { "id": "ATX10_YEAST", "url": "https://www.uniprot.org/uniprot/P25355", "type": "external" } ], "mass": 65206.0, "length": 563, "protein_name": "Ataxin-10 homolog", "gene_name": "CTR86", "organism": "Yeast", "refseq_name": "Ctr86p", "refseq_ac": [ { "id": "NP_009983", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009983", "type": "external" } ], "gene_names_uniprotkb": "CTR86; YCR54C", "gene_names_refseq": "CTR86", "protein_names_uniprotkb": "Ataxin-10 homolog; Copper transport protein 86", "protein_names_refseq": "Ctr86p", "tax_id": 559292, "disease": "spinocerebellar ataxia 10 (Disease Ontology:DOID:0050960)", "pathway": " (sce:YCR054C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562095;14562106;1574125;18407956;19779198;21126336;21177495;2204248;23749301;24374639;33481703;33491328", "class_list": "", "function": "May play a role in the regulation of cytokinesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR62", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0051301 cell division;GO:0032465 regulation of cytokinesis", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P25355-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25366-1", "uniprot_id": [ { "id": "OCA4_YEAST", "url": "https://www.uniprot.org/uniprot/P25366", "type": "external" } ], "mass": 41647.0, "length": 362, "protein_name": "Protein OCA4", "gene_name": "OCA4", "organism": "Yeast", "refseq_name": "Oca4p", "refseq_ac": [ { "id": "NP_010019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010019", "type": "external" } ], "gene_names_uniprotkb": "OCA4; YCR131; YCR95C", "gene_names_refseq": "OCA4", "protein_names_uniprotkb": "Protein OCA4; Oxidant-induced cell-cycle arrest protein 4", "protein_names_refseq": "Oca4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR095C)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "14562095;14562106;14671320;1574125;1574927;17287358;17563356;18205808;18407956;18845848;19779198;19795423;19823750;20702584;23749301;24374639;32597660;33481703;33491328", "class_list": "", "function": "Required for replication of Brome mosaic virus (BMV)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR95", "ec_number_list": [], "go_molecular_function": "GO:0016791 phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P25366-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25372-1", "uniprot_id": [ { "id": "TRX3_YEAST", "url": "https://www.uniprot.org/uniprot/P25372", "type": "external" } ], "mass": 14432.0, "length": 127, "protein_name": "Thioredoxin-3, mitochondrial", "gene_name": "TRX3", "organism": "Yeast", "refseq_name": "Trx3p", "refseq_ac": [ { "id": "NP_010006", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010006", "type": "external" } ], "gene_names_uniprotkb": "TRX3; YCR83W", "gene_names_refseq": "TRX3", "protein_names_uniprotkb": "Thioredoxin-3, mitochondrial", "protein_names_refseq": "Trx3p", "tax_id": 559292, "disease": "dilated cardiomyopathy (Disease Ontology:DOID:12930); glaucoma (Disease Ontology:DOID:1686); myocardial infarction (Disease Ontology:DOID:5844); myocarditis (Disease Ontology:DOID:820); intermediate coronary syndrome (Disease Ontology:DOID:8805); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (sce:YCR083W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10037727;14562106;1574125;24374639", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR84", "ec_number_list": [], "go_molecular_function": "GO:0015036 disulfide oxidoreductase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0034599 cellular response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P25372-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25380-1", "uniprot_id": [ { "id": "SPS22_YEAST", "url": "https://www.uniprot.org/uniprot/P25380", "type": "external" } ], "mass": 52008.0, "length": 463, "protein_name": "Sporulation-specific protein 22", "gene_name": "SPS22", "organism": "Yeast", "refseq_name": "Sps22p", "refseq_ac": [ { "id": "NP_009882", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009882", "type": "external" } ], "gene_names_uniprotkb": "SPS22; YCL48W", "gene_names_refseq": "SPS22", "protein_names_uniprotkb": "Sporulation-specific protein 22", "protein_names_refseq": "Sps22p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL048W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15590821;1574125;19684113;24374639", "class_list": "", "function": "Redundant with SPS2 for the organization of the beta-glucan layer of the spore wall., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VQW9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "GO:0030476 ascospore wall assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P25380-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25383-1", "uniprot_id": [ { "id": "YC21A_YEAST", "url": "https://www.uniprot.org/uniprot/P25383", "type": "external" } ], "mass": 49841.0, "length": 438, "protein_name": "Transposon Ty2-C Gag polyprotein", "gene_name": "TY2A-C", "organism": "Yeast", "refseq_name": "gag protein", "refseq_ac": [ { "id": "NP_009910", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009910", "type": "external" } ], "gene_names_uniprotkb": "TY2A-C; YCL20W; YCLWTy2-1 GAG", "gene_names_refseq": "", "protein_names_uniprotkb": "Transposon Ty2-C Gag polyprotein; TY2A; TYA; Transposon Ty2 protein A; Ty1-17 protein A", "protein_names_refseq": "gag protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL020W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "1574125;16093660;24374639;2989787;2997719;3010239;6322112;9582191", "class_list": "", "function": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty2 RNA and initiation of reverse transcription (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQZ5;Q07125", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P25383-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25568-1", "uniprot_id": [ { "id": "ATG22_YEAST", "url": "https://www.uniprot.org/uniprot/P25568", "type": "external" } ], "mass": 58844.0, "length": 528, "protein_name": "Autophagy-related protein 22", "gene_name": "ATG22", "organism": "Yeast", "refseq_name": "Atg22p", "refseq_ac": [ { "id": "NP_009892", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009892", "type": "external" } ], "gene_names_uniprotkb": "ATG22; AUT4; YCL38C", "gene_names_refseq": "ATG22; AUT4", "protein_names_uniprotkb": "Autophagy-related protein 22", "protein_names_refseq": "Atg22p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL038C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "11058089;14536056;1574125;16847258;17021250;18407956;19779198;22814378;24374639;33481703;33491328;8663607", "class_list": "", "function": "Vacuolar effluxer which mediate the efflux of leucine and other amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQX7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0006914 autophagy;GO:0032974 amino acid transmembrane export from vacuole", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P25568-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25579-1", "uniprot_id": [ { "id": "LRE1_YEAST", "url": "https://www.uniprot.org/uniprot/P25579", "type": "external" } ], "mass": 64792.0, "length": 583, "protein_name": "Laminarase-resistance protein LRE1", "gene_name": "LRE1", "organism": "Yeast", "refseq_name": "Lre1p", "refseq_ac": [ { "id": "NP_009879", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009879", "type": "external" } ], "gene_names_uniprotkb": "LRE1; YCL51W", "gene_names_refseq": "LRE1", "protein_names_uniprotkb": "Laminarase-resistance protein LRE1", "protein_names_refseq": "Lre1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL051W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "11532139;11580836;14574415;1574125;17563356;18407956;19684113;19779198;21177495;22218487;23749301;24374639;32597660;33481703;33491328;34965436;9090049", "class_list": "", "function": "Overexpression affects chitinase expression, cell separation and budding pattern, and increases trehalose accumulation and heat resistance by inhibiting protein kinase CBK1. Overexpression also suppresses temperature-induced hyperosmosensitivity and sensitivity to cell wall degrading enzymes. Overexpression of both LRE1 and PBN1 confers resistance to laminarinase., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 25, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQW5", "ec_number_list": [], "go_molecular_function": "GO:0004860 protein kinase inhibitor activity", "go_cellular_component": "GO:0005935 cellular bud neck", "go_biological_process": "GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P25579-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25584-1", "uniprot_id": [ { "id": "PEX34_YEAST", "url": "https://www.uniprot.org/uniprot/P25584", "type": "external" } ], "mass": 16593.0, "length": 144, "protein_name": "Peroxisomal membrane protein PEX34", "gene_name": "PEX34", "organism": "Yeast", "refseq_name": "Pex34p", "refseq_ac": [ { "id": "NP_009875", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009875", "type": "external" } ], "gene_names_uniprotkb": "PEX34; YCL433; YCL56C", "gene_names_refseq": "PEX34", "protein_names_uniprotkb": "Peroxisomal membrane protein PEX34; Peroxin-34", "protein_names_refseq": "Pex34p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL056C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "1441748;14562095;1574125;21441307;24374639", "class_list": "", "function": "In concert with the three peroxisome divisional factors, PEX11, PEX25 and PEX27, controls peroxisome morphology and abundance under conditions of peroxisome proliferation. Maintains mature peroxisomes in actively dividing cells., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQW1", "ec_number_list": [], "go_molecular_function": "GO:0160190 peroxisome-mitochondrion membrane tether activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005778 peroxisomal membrane;GO:0160189 peroxisomal-mitochondrial contact site", "go_biological_process": "GO:0007031 peroxisome organization", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P25584-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25585-1", "uniprot_id": [ { "id": "FYV5_YEAST", "url": "https://www.uniprot.org/uniprot/P25585", "type": "external" } ], "mass": 17139.0, "length": 152, "protein_name": "Protein FYV5", "gene_name": "FYV5", "organism": "Yeast", "refseq_name": "Fyv5p", "refseq_ac": [ { "id": "NP_009873", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009873", "type": "external" } ], "gene_names_uniprotkb": "FYV5; YCL58C", "gene_names_refseq": "FYV5; MDF1", "protein_names_uniprotkb": "Protein FYV5; Function required for yeast viability protein 5", "protein_names_refseq": "Fyv5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL058C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10234789;12663529;12829295;1574125;16251355;17322287;24374639", "class_list": "", "function": "Involved in maintaining an adequate ionic strength homeostasis of the cellular aqueous environment, necessary for normal growth rate. Required for survival upon exposure to K1 killer toxin and hence plays a role in cell wall glucan synthesis. Required for dithiothreitol (DTT) resistance. Involved in cell cycle progression., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQU8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0006873 intracellular monoatomic ion homeostasis;GO:0000750 pheromone-dependent signal transduction involved in conjugation with cellular fusion;GO:0071555 cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P25585-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25611-1", "uniprot_id": [ { "id": "RDS1_YEAST", "url": "https://www.uniprot.org/uniprot/P25611", "type": "external" } ], "mass": 95690.0, "length": 832, "protein_name": "Regulator of drug sensitivity 1", "gene_name": "RDS1", "organism": "Yeast", "refseq_name": "Rds1p", "refseq_ac": [ { "id": "NP_010031", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010031", "type": "external" } ], "gene_names_uniprotkb": "RDS1", "gene_names_refseq": "RDS1", "protein_names_uniprotkb": "Regulator of drug sensitivity 1", "protein_names_refseq": "Rds1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR106W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11943786;15343339;1574125;1641000;19158363;24374639;33491328", "class_list": "", "function": "Zinc cluster transcription factor involved in resistance to cycloheximide., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRA6", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0009410 response to xenobiotic stimulus", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P25611-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25619-1", "uniprot_id": [ { "id": "HSP30_YEAST", "url": "https://www.uniprot.org/uniprot/P25619", "type": "external" } ], "mass": 37045.0, "length": 332, "protein_name": "30 kDa heat shock protein", "gene_name": "HSP30", "organism": "Yeast", "refseq_name": "Hsp30p", "refseq_ac": [ { "id": "NP_009950", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009950", "type": "external" } ], "gene_names_uniprotkb": "HSP30; YCR21C", "gene_names_refseq": "HSP30; YRO1", "protein_names_uniprotkb": "30 kDa heat shock protein", "protein_names_refseq": "Hsp30p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR021C)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "11875433;14562106;1574125;16847258;17563356;18407956;19779198;21126336;21177495;22405770;23749301;24374639;32597660;33491328;8319300", "class_list": "", "function": "Probably cooperates with other heat shock proteins in the translocation of polypeptides through membranes. It may counteract the altering effect of heat shock on the plasma membrane., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 1, "mined_n_glycosites": 1, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VR31;Q04556", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane", "go_biological_process": "GO:0032780 negative regulation of ATP-dependent activity", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P25619-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000100000001.010.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25642-1", "uniprot_id": [ { "id": "IMG2_YEAST", "url": "https://www.uniprot.org/uniprot/P25642", "type": "external" } ], "mass": 16380.0, "length": 146, "protein_name": "Large ribosomal subunit protein mL49", "gene_name": "IMG2", "organism": "Yeast", "refseq_name": "mitochondrial 54S ribosomal protein mL49 IMG2", "refseq_ac": [ { "id": "NP_009996", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009996", "type": "external" } ], "gene_names_uniprotkb": "IMG2; YCR71C", "gene_names_refseq": "IMG2; mL49", "protein_names_uniprotkb": "Large ribosomal subunit protein mL49; 54S ribosomal protein IMG2, mitochondrial; Integrity of mitochondrial genome protein 2", "protein_names_refseq": "mitochondrial 54S ribosomal protein mL49 IMG2", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR071C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12392552;14562095;14562106;14576278;1574125;17322287;24374639;24675956;25609543", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR73;Q6B2B0;Q96VG7", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P25642-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25649-1", "uniprot_id": [ { "id": "AHC2_YEAST", "url": "https://www.uniprot.org/uniprot/P25649", "type": "external" } ], "mass": 15117.0, "length": 128, "protein_name": "ADA histone acetyltransferase complex component 2", "gene_name": "AHC2", "organism": "Yeast", "refseq_name": "Ahc2p", "refseq_ac": [ { "id": "NP_010005", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010005", "type": "external" } ], "gene_names_uniprotkb": "AHC2; YCR82W", "gene_names_refseq": "AHC2", "protein_names_uniprotkb": "ADA histone acetyltransferase complex component 2; Putative transcriptional regulator AHC2", "protein_names_refseq": "Ahc2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR082W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;14562106;1574125;16464826;21734642;24374639", "class_list": "", "function": "Component of the ADA histone acetyltransferase complex, which preferentially acetylates nucleosomal histones H3 (to form H3K14ac and H3K18ac) and H2B., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR83", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0140671 ADA complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P25649-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P25659-1", "uniprot_id": [ { "id": "FUB1_YEAST", "url": "https://www.uniprot.org/uniprot/P25659", "type": "external" } ], "mass": 26756.0, "length": 250, "protein_name": "Silencing boundary-establishment protein FUB1", "gene_name": "FUB1", "organism": "Yeast", "refseq_name": "Fub1p", "refseq_ac": [ { "id": "NP_010001", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010001", "type": "external" } ], "gene_names_uniprotkb": "FUB1; YCR76C", "gene_names_refseq": "FUB1", "protein_names_uniprotkb": "Silencing boundary-establishment protein FUB1; Function of boundary protein 1; Proteasome inhibitor PI31-like protein FUB1", "protein_names_refseq": "Fub1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR076C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;1574125;22362029;24374639;33491328", "class_list": "", "function": "Plays a role in the establishment of transcriptional silencing boundaries, preventing the propagation of heterochromatic silencing., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR79", "ec_number_list": [], "go_molecular_function": "GO:0070628 proteasome binding", "go_cellular_component": "", "go_biological_process": "GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P25659-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P26637-1", "uniprot_id": [ { "id": "SYLC_YEAST", "url": "https://www.uniprot.org/uniprot/P26637", "type": "external" } ], "mass": 124142.0, "length": 1090, "protein_name": "Leucine--tRNA ligase, cytoplasmic", "gene_name": "CDC60", "organism": "Yeast", "refseq_name": "leucine--tRNA ligase CDC60", "refseq_ac": [ { "id": "NP_015165", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015165", "type": "external" } ], "gene_names_uniprotkb": "CDC60; P2564", "gene_names_refseq": "CDC60", "protein_names_uniprotkb": "Leucine--tRNA ligase, cytoplasmic; 6.1.1.4; LeuRS; Leucyl-tRNA synthetase", "protein_names_refseq": "leucine--tRNA ligase CDC60", "tax_id": 559292, "disease": "infantile liver failure syndrome 1 (Disease Ontology:DOID:0080717)", "pathway": " (sce:YPL160W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "1398122;14562106;18407956;19779198;19795423;19823750;22814378;23749301;24374639;27821475;32597660;33481703;33491328;33502312;8948103;9169875", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3K8", "ec_number_list": [ { "id": "6.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.4", "type": "external" } ], "go_molecular_function": "GO:0002161 aminoacyl-tRNA deacylase activity;GO:0004823 leucine-tRNA ligase activity;GO:1990825 sequence-specific mRNA binding;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006429 leucyl-tRNA aminoacylation;GO:1903432 regulation of TORC1 signaling", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P26637-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P28625-1", "uniprot_id": [ { "id": "YIM1_YEAST", "url": "https://www.uniprot.org/uniprot/P28625", "type": "external" } ], "mass": 41637.0, "length": 365, "protein_name": "Protein YIM1", "gene_name": "YIM1", "organism": "Yeast", "refseq_name": "Yim1p", "refseq_ac": [ { "id": "NP_013872", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013872", "type": "external" } ], "gene_names_uniprotkb": "YIM1; YM8520.01; YM9375.22", "gene_names_refseq": "YIM1", "protein_names_uniprotkb": "Protein YIM1", "protein_names_refseq": "Yim1p", "tax_id": 559292, "disease": "optic atrophy 10 (Disease Ontology:DOID:0111434)", "pathway": " (sce:YMR152W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10515935;12077312;14562106;14576278;17322287;18407956;1886606;24374639;33491328;9169872", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZX3", "ec_number_list": [], "go_molecular_function": "GO:0018455 alcohol dehydrogenase [NAD(P)+] activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005811 lipid droplet", "go_biological_process": "GO:0006974 DNA damage response;GO:0006744 ubiquinone biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P28625-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P28778-1", "uniprot_id": [ { "id": "RT06_YEAST", "url": "https://www.uniprot.org/uniprot/P28778", "type": "external" } ], "mass": 15021.0, "length": 131, "protein_name": "Small ribosomal subunit protein bS6m", "gene_name": "MRP17", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein bS6m MRP17", "refseq_ac": [ { "id": "NP_012923", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012923", "type": "external" } ], "gene_names_uniprotkb": "MRP17", "gene_names_refseq": "MRP17; bS6m", "protein_names_uniprotkb": "Small ribosomal subunit protein bS6m; 37S ribosomal protein MRP17, mitochondrial; YmS16", "protein_names_refseq": "mitochondrial 37S ribosomal protein bS6m MRP17", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL003C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "12392552;1279374;14562095;14576278;22814378;24374639;25609543;28154081;8196765;8668135;9151978", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXT4", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome;GO:0070181 small ribosomal subunit rRNA binding", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P28778-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P30402-1", "uniprot_id": [ { "id": "PYRX_YEAST", "url": "https://www.uniprot.org/uniprot/P30402", "type": "external" } ], "mass": 24811.0, "length": 227, "protein_name": "Orotate phosphoribosyltransferase 2", "gene_name": "URA10", "organism": "Yeast", "refseq_name": "orotate phosphoribosyltransferase URA10", "refseq_ac": [ { "id": "NP_013998", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013998", "type": "external" } ], "gene_names_uniprotkb": "URA10; YM8156.13C", "gene_names_refseq": "URA10", "protein_names_uniprotkb": "Orotate phosphoribosyltransferase 2; 2.4.2.10; OPRT 2; OPRTase 2", "protein_names_refseq": "orotate phosphoribosyltransferase URA10", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR271C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;17322287;2182197;24374639;7882422;9169872", "class_list": "", "function": "Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W097", "ec_number_list": [ { "id": "2.4.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.10", "type": "external" } ], "go_molecular_function": "GO:0004588 orotate phosphoribosyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006221 pyrimidine nucleotide biosynthetic process;GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process;GO:0044205 'de novo' UMP biosynthetic process;GO:0046132 pyrimidine ribonucleoside biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P30402-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P30777-1", "uniprot_id": [ { "id": "GPI10_YEAST", "url": "https://www.uniprot.org/uniprot/P30777", "type": "external" } ], "mass": 72566.0, "length": 616, "protein_name": "GPI mannosyltransferase 3", "gene_name": "GPI10", "organism": "Yeast", "refseq_name": "putative glycosylphosphatidylinositol-alpha 1,2 mannosyltransferase", "refseq_ac": [ { "id": "NP_011373", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011373", "type": "external" } ], "gene_names_uniprotkb": "GPI10", "gene_names_refseq": "GPI10", "protein_names_uniprotkb": "GPI mannosyltransferase 3; 2.4.1.-; GPI mannosyltransferase III; GPI-MT-III; Glycosylphosphatidylinositol-anchor biosynthesis protein 10", "protein_names_refseq": "putative glycosylphosphatidylinositol-alpha 1,2 mannosyltransferase", "tax_id": 559292, "disease": "developmental and epileptic encephalopathy 80 (Disease Ontology:DOID:0112216); sleeping sickness (Disease Ontology:DOID:10112)", "pathway": " (sce:YGL142C); (R-SCE-162710)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "11159918;1475194;16847258;24374639;9046099;9169869;9576863;9639537", "class_list": "glycogene;glycosyltransferase", "function": "Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VU07", "ec_number_list": [ { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" } ], "go_molecular_function": "GO:0000026 alpha-1,2-mannosyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006506 GPI anchor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P30777-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000000.000.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32317-1", "uniprot_id": [ { "id": "AFG1_YEAST", "url": "https://www.uniprot.org/uniprot/P32317", "type": "external" } ], "mass": 58265.0, "length": 509, "protein_name": "Protein AFG1", "gene_name": "AFG1", "organism": "Yeast", "refseq_name": "Afg1p", "refseq_ac": [ { "id": "NP_010862", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010862", "type": "external" } ], "gene_names_uniprotkb": "AFG1; AFG", "gene_names_refseq": "AFG1", "protein_names_uniprotkb": "Protein AFG1", "protein_names_refseq": "Afg1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YEL052W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "1441755;14562106;17322287;19684113;24374639;9169868", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLJ8;E9P923", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0034599 cellular response to oxidative stress;GO:0006515 protein quality control for misfolded or incompletely synthesized proteins;GO:0141164 mitochondrial protein quality control", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P32317-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32351-1", "uniprot_id": [ { "id": "IMPX_YEAST", "url": "https://www.uniprot.org/uniprot/P32351", "type": "external" } ], "mass": 39071.0, "length": 346, "protein_name": "Sugar utilization regulatory protein IMP2", "gene_name": "IMP2'", "organism": "Yeast", "refseq_name": "Imp21p", "refseq_ac": [ { "id": "NP_012112", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012112", "type": "external" } ], "gene_names_uniprotkb": "IMP2'; IMP2", "gene_names_refseq": "IMP21; IMP2", "protein_names_uniprotkb": "Sugar utilization regulatory protein IMP2", "protein_names_refseq": "Imp21p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL154C)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "14562106;1561839;17330950;19779198;20702584;21126336;21177495;22218487;23749301;24374639;32597660;33481703;33491328;9169870", "class_list": "", "function": "Controls the nucleo-mitochondrial dependence of galactose, maltose and raffinose utilization. Becomes essential in the absence of functioning mitochondria., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVD3", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P32351-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32375-1", "uniprot_id": [ { "id": "ALN_YEAST", "url": "https://www.uniprot.org/uniprot/P32375", "type": "external" } ], "mass": 50126.0, "length": 460, "protein_name": "Allantoinase", "gene_name": "DAL1", "organism": "Yeast", "refseq_name": "allantoinase", "refseq_ac": [ { "id": "NP_012293", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012293", "type": "external" } ], "gene_names_uniprotkb": "DAL1", "gene_names_refseq": "DAL1", "protein_names_uniprotkb": "Allantoinase; 3.5.2.5", "protein_names_refseq": "allantoinase", "tax_id": 559292, "disease": "Ritscher-Schinzel syndrome (Disease Ontology:DOID:0060565); dihydropyrimidinase deficiency (Disease Ontology:DOID:0111629); hypothyroidism (Disease Ontology:DOID:1459); status epilepticus (Disease Ontology:DOID:1824); brain ischemia (Disease Ontology:DOID:2316); purine-pyrimidine metabolic disorder (Disease Ontology:DOID:653)", "pathway": " (sce:YIR027C)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "1803816;24374639;9169870", "class_list": "", "function": "Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring. Involved in the utilization of purines as secondary nitrogen sources, when primary sources are limiting., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVV8", "ec_number_list": [ { "id": "3.5.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.2.5", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0050897 cobalt ion binding;GO:0004038 allantoinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006145 purine nucleobase catabolic process;GO:0009442 allantoin assimilation pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P32375-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32388-1", "uniprot_id": [ { "id": "RM49_YEAST", "url": "https://www.uniprot.org/uniprot/P32388", "type": "external" } ], "mass": 16021.0, "length": 137, "protein_name": "Large ribosomal subunit protein mL61", "gene_name": "MRP49", "organism": "Yeast", "refseq_name": "mitochondrial 54S ribosomal protein mL61 MRP49", "refseq_ac": [ { "id": "NP_012754", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012754", "type": "external" } ], "gene_names_uniprotkb": "MRP49; YKL631", "gene_names_refseq": "MRP49; mL61", "protein_names_uniprotkb": "Large ribosomal subunit protein mL61; 54S ribosomal protein MRP49, mitochondrial", "protein_names_refseq": "mitochondrial 54S ribosomal protein mL61 MRP49", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL167C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14576278;1544898;17322287;24374639;24675956;25609543;8091858;8196765", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane (PubMed:24675956, PubMed:25609543). mL61 is not essential in cells grown at 30 degrees Celsius but is required for mitochondrial translation in cells grown at 18 degrees Celsius., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VX32", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P32388-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32435-1", "uniprot_id": [ { "id": "MFAL2_YEAST", "url": "https://www.uniprot.org/uniprot/P32435", "type": "external" } ], "mass": 13271.0, "length": 120, "protein_name": "Mating factor alpha-2", "gene_name": "MF(ALPHA)2", "organism": "Yeast", "refseq_name": "Mf(Alpha)2p", "refseq_ac": [ { "id": "NP_011426", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011426", "type": "external" } ], "gene_names_uniprotkb": "MF(ALPHA)2; MF-ALPHA-2; MFAL2", "gene_names_refseq": "MF(ALPHA)2", "protein_names_uniprotkb": "Mating factor alpha-2; Alpha-2 mating pheromone", "protein_names_refseq": "Mf(Alpha)2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL089C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "21177495;24374639;340452;6306574;9169869;9290212", "class_list": "", "function": "The active factor is excreted into the culture medium by haploid cells of the alpha mating type and acts on cells of the opposite mating type (type A). It mediates the conjugation process between the two types by inhibiting the initiation of DNA synthesis in type a cells and synchronizing them with type alpha., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VU56", "ec_number_list": [], "go_molecular_function": "GO:0000772 mating pheromone activity;GO:1903135 cupric ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0007618 mating;GO:0000750 pheromone-dependent signal transduction involved in conjugation with cellular fusion", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P32435-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32448-1", "uniprot_id": [ { "id": "ASF2_YEAST", "url": "https://www.uniprot.org/uniprot/P32448", "type": "external" } ], "mass": 59347.0, "length": 525, "protein_name": "Anti-silencing protein 2", "gene_name": "ASF2", "organism": "Yeast", "refseq_name": "Asf2p", "refseq_ac": [ { "id": "NP_010084", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010084", "type": "external" } ], "gene_names_uniprotkb": "ASF2; D1219", "gene_names_refseq": "ASF2", "protein_names_uniprotkb": "Anti-silencing protein 2", "protein_names_refseq": "Asf2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL197C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562106;18407956;19779198;24374639;33491328;8896272;9046097;9169867;9290207", "class_list": "", "function": "Derepression of silent mating type loci when overexpressed., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VRF7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0030466 silent mating-type cassette heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P32448-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32452-1", "uniprot_id": [ { "id": "PHA2_YEAST", "url": "https://www.uniprot.org/uniprot/P32452", "type": "external" } ], "mass": 38225.0, "length": 334, "protein_name": "Probable prephenate dehydratase", "gene_name": "PHA2", "organism": "Yeast", "refseq_name": "prephenate dehydratase PHA2", "refseq_ac": [ { "id": "NP_014083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014083", "type": "external" } ], "gene_names_uniprotkb": "PHA2; N0351", "gene_names_refseq": "PHA2", "protein_names_uniprotkb": "Probable prephenate dehydratase; 4.2.1.51; PDT; Phenylalanine-requiring protein 2", "protein_names_refseq": "prephenate dehydratase PHA2", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL316C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12748633;14562095;14562106;1532796;24374639;6060189;7502583;9169873", "class_list": "", "function": "Catayzes the decarboxylation/dehydration of prephenate to phenylpyruvate., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0M9", "ec_number_list": [ { "id": "4.2.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.51", "type": "external" } ], "go_molecular_function": "GO:0004664 prephenate dehydratase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0009094 L-phenylalanine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P32452-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32453-1", "uniprot_id": [ { "id": "ATP11_YEAST", "url": "https://www.uniprot.org/uniprot/P32453", "type": "external" } ], "mass": 36851.0, "length": 318, "protein_name": "Protein ATP11, mitochondrial", "gene_name": "ATP11", "organism": "Yeast", "refseq_name": "Atp11p", "refseq_ac": [ { "id": "NP_014084", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014084", "type": "external" } ], "gene_names_uniprotkb": "ATP11; N0357", "gene_names_refseq": "ATP11", "protein_names_uniprotkb": "Protein ATP11, mitochondrial", "protein_names_refseq": "Atp11p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL315C)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "14562106;1532796;17322287;17330950;19779198;19795423;19823750;20702584;23749301;24374639;33481703;33491328;7502583;9169873", "class_list": "", "function": "Essential for the assembly of the mitochondrial F1-F0 complex. May interact with the alpha and/or beta subunits of F1-ATPase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0N0", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0140777 protein-containing complex stabilizing activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0007005 mitochondrion organization;GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P32453-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32493-1", "uniprot_id": [ { "id": "AEP1_YEAST", "url": "https://www.uniprot.org/uniprot/P32493", "type": "external" } ], "mass": 59748.0, "length": 518, "protein_name": "ATPase expression protein 1, mitochondrial", "gene_name": "AEP1", "organism": "Yeast", "refseq_name": "Aep1p", "refseq_ac": [ { "id": "NP_013780", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013780", "type": "external" } ], "gene_names_uniprotkb": "AEP1; NCA1; YM9916.03", "gene_names_refseq": "AEP1; NCA1", "protein_names_uniprotkb": "ATPase expression protein 1, mitochondrial; Nuclear control of ATPase messenger RNA expression protein 1", "protein_names_refseq": "Aep1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR064W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;14562106;24374639;8358819;8445655;9169872", "class_list": "", "function": "Required for translation of the mitochondrial OLI1 transcript encoding subunit 9 of mitochondrial ATP synthase., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZN8;P32446", "ec_number_list": [], "go_molecular_function": "GO:0045182 translation regulator activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006417 regulation of translation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P32493-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32572-1", "uniprot_id": [ { "id": "SPS18_YEAST", "url": "https://www.uniprot.org/uniprot/P32572", "type": "external" } ], "mass": 34240.0, "length": 300, "protein_name": "Sporulation protein SPS18", "gene_name": "SPS18", "organism": "Yeast", "refseq_name": "Sps18p", "refseq_ac": [ { "id": "NP_014195", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014195", "type": "external" } ], "gene_names_uniprotkb": "SPS18; N1354; SPX18", "gene_names_refseq": "SPS18; SPX18", "protein_names_uniprotkb": "Sporulation protein SPS18; Sporulation-specific protein SPX18", "protein_names_refseq": "Sps18p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL204C); (R-SCE-6807878); (R-SCE-6811434)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "17322287;24374639;7725799;7969036;9169873", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0Y5", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0030100 regulation of endocytosis;GO:0032012 regulation of ARF protein signal transduction;GO:0030437 ascospore formation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P32572-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32583-1", "uniprot_id": [ { "id": "SRP40_YEAST", "url": "https://www.uniprot.org/uniprot/P32583", "type": "external" } ], "mass": 41015.0, "length": 406, "protein_name": "Suppressor protein SRP40", "gene_name": "SRP40", "organism": "Yeast", "refseq_name": "Srp40p", "refseq_ac": [ { "id": "NP_013018", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013018", "type": "external" } ], "gene_names_uniprotkb": "SRP40; YKR412A", "gene_names_refseq": "SRP40", "protein_names_uniprotkb": "Suppressor protein SRP40", "protein_names_refseq": "Srp40p", "tax_id": 559292, "disease": "", "pathway": " (sce:YKR092C)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "14562106;15604408;17287358;17330950;17563356;17873058;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;23749301;24374639;24909858;32597660;33481703;33491328;8154186;8196765;8516295", "class_list": "", "function": "Not known; weak suppressor of a mutant of the subunit AC40 of DNA dependent RNA polymerase I and III., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VXF2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0006913 nucleocytoplasmic transport", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P32583-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32606-1", "uniprot_id": [ { "id": "PT127_YEAST", "url": "https://www.uniprot.org/uniprot/P32606", "type": "external" } ], "mass": 93408.0, "length": 800, "protein_name": "Putative mitochondrial translation system component PET127", "gene_name": "PET127", "organism": "Yeast", "refseq_name": "Pet127p", "refseq_ac": [ { "id": "NP_014660", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014660", "type": "external" } ], "gene_names_uniprotkb": "PET127; OR26.07", "gene_names_refseq": "PET127", "protein_names_uniprotkb": "Putative mitochondrial translation system component PET127", "protein_names_refseq": "Pet127p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR017W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "1279374;14562106;24374639;33229814;33481703;9169874", "class_list": "", "function": "Could be a component of the mitochondrial translation system with a role in promoting accuracy of translational initiation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6W283", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005740 mitochondrial envelope", "go_biological_process": "GO:0000964 mitochondrial RNA 5'-end processing;GO:0000957 mitochondrial RNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P32606-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32616-1", "uniprot_id": [ { "id": "YEF5_YEAST", "url": "https://www.uniprot.org/uniprot/P32616", "type": "external" } ], "mass": 16469.0, "length": 141, "protein_name": "Uncharacterized protein YEL045C", "gene_name": "SYGP-ORF33", "organism": "Yeast", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SYGP-ORF33", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein YEL045C", "protein_names_refseq": "", "tax_id": 559292, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 7, "publication_id_list": "12453218;14993228;15060153;15937126;17322287;24374639;9169868", "class_list": "", "function": "Required for optimal growth under alkaline conditions., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P32616-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32618-1", "uniprot_id": [ { "id": "YEF3_YEAST", "url": "https://www.uniprot.org/uniprot/P32618", "type": "external" } ], "mass": 106133.0, "length": 956, "protein_name": "Uncharacterized protein YEL043W", "gene_name": "SYGP-ORF14", "organism": "Yeast", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SYGP-ORF14", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein YEL043W", "protein_names_refseq": "", "tax_id": 559292, "disease": "", "pathway": " (sce:YEL043W)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "14562106;17287358;17322287;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;23749301;24374639;32597660;33229814;33481703;33491328;34965436;8994808;9169868", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 11, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 11, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 11, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 38, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 10, "binding_glycan_count": 0, "secondary_ac_list": "D3DLK6;Q66RC2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0071944 cell periphery", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 3.5, "record_id": "P32618-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32634-1", "uniprot_id": [ { "id": "PMD1_YEAST", "url": "https://www.uniprot.org/uniprot/P32634", "type": "external" } ], "mass": 195383.0, "length": 1753, "protein_name": "Negative regulator of sporulation PMD1", "gene_name": "PMD1", "organism": "Yeast", "refseq_name": "Pmd1p", "refseq_ac": [ { "id": "NP_011058", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011058", "type": "external" } ], "gene_names_uniprotkb": "PMD1; SYGP-ORF50", "gene_names_refseq": "PMD1", "protein_names_uniprotkb": "Negative regulator of sporulation PMD1", "protein_names_refseq": "Pmd1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER132C); (R-SCE-6798695)", "pathway_count": 2, "publication_count": 25, "publication_id_list": "12524333;14562095;14562106;15665377;17330950;17563356;18407956;19087957;19684113;19779198;19795423;19823750;20489023;21126336;21177495;23749301;24374639;31208443;32597660;33229814;33481703;33491328;34965436;9169868;9383076", "class_list": "", "function": "Negatively regulates early sporulation-specific genes. Seems to exert its function by positively regulating the Ras/cAMP pathway. Required for growth under alkaline conditions. Acts synergetically with MDS3., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 10, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 10, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 10, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 102, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "D3DM38", "ec_number_list": [], "go_molecular_function": "GO:0004601 peroxidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0045454 cell redox homeostasis;GO:0030437 ascospore formation", "synthesized_glycan_count": 0, "hit_score": 3.7, "record_id": "P32634-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32770-1", "uniprot_id": [ { "id": "DRI1_YEAST", "url": "https://www.uniprot.org/uniprot/P32770", "type": "external" } ], "mass": 79299.0, "length": 719, "protein_name": "Putative RNA-binding protein involved in heterochromatin assembly", "gene_name": "NRP1", "organism": "Yeast", "refseq_name": "Nrp1p", "refseq_ac": [ { "id": "NP_010114", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010114", "type": "external" } ], "gene_names_uniprotkb": "NRP1; ARP1; ARP", "gene_names_refseq": "NRP1", "protein_names_uniprotkb": "Putative RNA-binding protein involved in heterochromatin assembly; Asparagine-rich protein; Protein ARP", "protein_names_refseq": "Nrp1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL167C)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "14562106;15665377;17330950;17563356;18407956;19779198;21126336;23749301;24374639;32597660;33229814;33481703;33491328;8483449;9169867", "class_list": "", "function": "May play a role in chromatin organization., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 17, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VRI4;Q12228", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005694 chromosome;GO:0010494 cytoplasmic stress granule", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P32770-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32775-1", "uniprot_id": [ { "id": "GLGB_YEAST", "url": "https://www.uniprot.org/uniprot/P32775", "type": "external" } ], "mass": 81116.0, "length": 704, "protein_name": "1,4-alpha-glucan-branching enzyme", "gene_name": "GLC3", "organism": "Yeast", "refseq_name": "1,4-alpha-glucan branching enzyme", "refseq_ac": [ { "id": "NP_010905", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010905", "type": "external" } ], "gene_names_uniprotkb": "GLC3", "gene_names_refseq": "GHA1; GLC3", "protein_names_uniprotkb": "1,4-alpha-glucan-branching enzyme; 2.4.1.18; Glycogen-branching enzyme", "protein_names_refseq": "1,4-alpha-glucan branching enzyme", "tax_id": 559292, "disease": "porphyria (Disease Ontology:DOID:13268); glycogen storage disease IV (Disease Ontology:DOID:2750); pulmonary tuberculosis (Disease Ontology:DOID:2957)", "pathway": " (sce:YEL011W); (R-SCE-3322077)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "14562106;1634552;18407956;19779198;24374639;33481703;33491328;38832010;9169868", "class_list": "", "function": "Glycogen-branching enzyme participates in the glycogen biosynthetic process along with glycogenin and glycogen synthase. Generates alpha-1,6-glucosidic branches from alpha-1,4-linked glucose chains, to increase solubility of the glycogen polymer., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLN8", "ec_number_list": [ { "id": "2.4.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.11", "type": "external" }, { "id": "2.4.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.18", "type": "external" }, { "id": "2.4.1.186", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.186", "type": "external" } ], "go_molecular_function": "GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0003844 1,4-alpha-glucan branching enzyme activity;GO:0043169 cation binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0005978 glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P32775-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32806-1", "uniprot_id": [ { "id": "GYP6_YEAST", "url": "https://www.uniprot.org/uniprot/P32806", "type": "external" } ], "mass": 53815.0, "length": 458, "protein_name": "GTPase-activating protein GYP6", "gene_name": "GYP6", "organism": "Yeast", "refseq_name": "GTPase-activating protein GYP6", "refseq_ac": [ { "id": "NP_012491", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012491", "type": "external" } ], "gene_names_uniprotkb": "GYP6; J1202", "gene_names_refseq": "GYP6", "protein_names_uniprotkb": "GTPase-activating protein GYP6; GAP for YPT6", "protein_names_refseq": "GTPase-activating protein GYP6", "tax_id": 559292, "disease": "obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YJL044C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562106;18407956;23749301;24374639;32597660;33481703;33491328;8441469;8641269", "class_list": "", "function": "Stimulates specifically the GTPase activity of YPT6., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWE0", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005829 cytosol;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0090630 activation of GTPase activity", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P32806-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32857-1", "uniprot_id": [ { "id": "PTM1_YEAST", "url": "https://www.uniprot.org/uniprot/P32857", "type": "external" } ], "mass": 60018.0, "length": 523, "protein_name": "Membrane protein PTM1", "gene_name": "PTM1", "organism": "Yeast", "refseq_name": "Ptm1p", "refseq_ac": [ { "id": "NP_012885", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012885", "type": "external" } ], "gene_names_uniprotkb": "PTM1; YKL252", "gene_names_refseq": "PTM1", "protein_names_uniprotkb": "Membrane protein PTM1", "protein_names_refseq": "Ptm1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL039W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12748633;1481573;16107716;18407956;21177495;24374639;32597660;33491328;8196765", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VXP7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0016020 membrane;GO:0031901 early endosome membrane", "go_biological_process": "GO:0042147 retrograde transport, endosome to Golgi", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P32857-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32858-1", "uniprot_id": [ { "id": "AIM26_YEAST", "url": "https://www.uniprot.org/uniprot/P32858", "type": "external" } ], "mass": 12936.0, "length": 118, "protein_name": "Altered inheritance of mitochondria protein 26, mitochondrial", "gene_name": "AIM26", "organism": "Yeast", "refseq_name": "Aim26p", "refseq_ac": [ { "id": "NP_012887", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012887", "type": "external" } ], "gene_names_uniprotkb": "AIM26; YKL250", "gene_names_refseq": "AIM26", "protein_names_uniprotkb": "Altered inheritance of mitochondria protein 26, mitochondrial", "protein_names_refseq": "Aim26p", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL037W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "1481573;19300474;19793921;20364111;24374639;8196765", "class_list": "", "function": "Involved in selective mitochondria autophagy (mitophagy)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VXP9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0016236 macroautophagy;GO:0000422 autophagy of mitochondrion", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P32858-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P32902-1", "uniprot_id": [ { "id": "RT04_YEAST", "url": "https://www.uniprot.org/uniprot/P32902", "type": "external" } ], "mass": 44152.0, "length": 394, "protein_name": "Small ribosomal subunit protein uS2m", "gene_name": "MRP4", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein uS2m MRP4", "refseq_ac": [ { "id": "NP_011859", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011859", "type": "external" } ], "gene_names_uniprotkb": "MRP4; MRP4A", "gene_names_refseq": "MRP4; uS2m", "protein_names_uniprotkb": "Small ribosomal subunit protein uS2m; 37S ribosomal protein MRP4, mitochondrial", "protein_names_refseq": "mitochondrial 37S ribosomal protein uS2m MRP4", "tax_id": 559292, "disease": "intrinsic cardiomyopathy (Disease Ontology:DOID:0060036); combined oxidative phosphorylation deficiency 36 (Disease Ontology:DOID:0111482)", "pathway": " (sce:YHL004W); (R-SCE-9837999)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "11278769;12392552;14562095;14562106;14576278;1531984;17322287;24374639;25609543;28154081;8091229", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKR0", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P32902-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P33303-1", "uniprot_id": [ { "id": "SFC1_YEAST", "url": "https://www.uniprot.org/uniprot/P33303", "type": "external" } ], "mass": 35340.0, "length": 322, "protein_name": "Succinate/fumarate mitochondrial transporter", "gene_name": "SFC1", "organism": "Yeast", "refseq_name": "Sfc1p", "refseq_ac": [ { "id": "NP_012629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012629", "type": "external" } ], "gene_names_uniprotkb": "SFC1; ACR1; J1921", "gene_names_refseq": "ACR1; SFC1", "protein_names_uniprotkb": "Succinate/fumarate mitochondrial transporter; Regulator of acetyl-CoA synthase activity", "protein_names_refseq": "Sfc1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR095W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "17322287;24374639;7908717;8641269;9395087", "class_list": "", "function": "Transports cytoplasmic succinate, derived from isocitrate by the action of isocitrate lyase in the cytosol, into the mitochondrial matrix in exchange for fumarate., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWR4", "ec_number_list": [], "go_molecular_function": "GO:0005469 succinate:fumarate antiporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0015744 succinate transport;GO:0015741 fumarate transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P33303-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P33304-1", "uniprot_id": [ { "id": "AFR1_YEAST", "url": "https://www.uniprot.org/uniprot/P33304", "type": "external" } ], "mass": 71364.0, "length": 620, "protein_name": "Protein AFR1", "gene_name": "AFR1", "organism": "Yeast", "refseq_name": "Afr1p", "refseq_ac": [ { "id": "NP_010370", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010370", "type": "external" } ], "gene_names_uniprotkb": "AFR1; D4471", "gene_names_refseq": "AFR1", "protein_names_uniprotkb": "Protein AFR1", "protein_names_refseq": "Afr1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR085C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "15665377;17322287;17330950;19779198;23749301;24374639;32597660;33481703;33491328;8413281;9169867", "class_list": "", "function": "Acts in conjunction with the alpha-factor receptor to promote morphogenesis and adaptation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS72", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding", "go_cellular_component": "GO:0005777 peroxisome;GO:0001400 mating projection base", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0032185 septin cytoskeleton organization;GO:0007618 mating;GO:0000753 cell morphogenesis involved in conjugation with cellular fusion;GO:0097271 protein localization to bud neck", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P33304-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P33331-1", "uniprot_id": [ { "id": "NTF2_YEAST", "url": "https://www.uniprot.org/uniprot/P33331", "type": "external" } ], "mass": 14453.0, "length": 125, "protein_name": "Nuclear transport factor 2", "gene_name": "NTF2", "organism": "Yeast", "refseq_name": "Ran GTPase-binding protein NTF2", "refseq_ac": [ { "id": "NP_010925", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010925", "type": "external" } ], "gene_names_uniprotkb": "NTF2", "gene_names_refseq": "NTF2", "protein_names_uniprotkb": "Nuclear transport factor 2; NTF-2; Nuclear transport factor P10", "protein_names_refseq": "Ran GTPase-binding protein NTF2", "tax_id": 559292, "disease": "diabetic retinopathy (Disease Ontology:DOID:8947)", "pathway": " (sce:YER009W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12065398;17322287;22106047;22814378;24374639;33481703;33491328;8600522;8889515;9169868", "class_list": "", "function": "Facilitates protein transport into the nucleus. Interacts with various nucleoporins and with Ran-GDP. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import. In vitro, the NTF2-Ran-GDP association, in the presence of GTP, triggers dissociation of the karyopherin alpha-beta complex, allowing nuclear translocation of karyopherin alpha and the NLS substrate., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLQ6", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding;GO:0061608 nuclear import signal receptor activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0044613 nuclear pore central transport channel", "go_biological_process": "GO:0006913 nucleocytoplasmic transport;GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P33331-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P33335-1", "uniprot_id": [ { "id": "SGE1_YEAST", "url": "https://www.uniprot.org/uniprot/P33335", "type": "external" } ], "mass": 59426.0, "length": 543, "protein_name": "Protein SGE1", "gene_name": "SGE1", "organism": "Yeast", "refseq_name": "Sge1p", "refseq_ac": [ { "id": "NP_015524", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015524", "type": "external" } ], "gene_names_uniprotkb": "SGE1; NOR1; P9677.3", "gene_names_refseq": "NOR1; SGE1", "protein_names_uniprotkb": "Protein SGE1; 10-N-nonyl acridine orange resistance protein; Crystal violet resistance protein", "protein_names_refseq": "Sge1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR198W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "16847258;24374639;8058039;8349103;9169875;9271105;9483795", "class_list": "", "function": "Drug export permease. Multi-copy suppressor of loss-of-function mutation of GAL11. Involved specifically in transcription of GAL4-dependent genes. Can link GAL4 with the basal transcription machinery if GAL11 is missing. Confers resistance to 10-N-nonyl acridine orange (NAO) and in general to cationic dyes., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4J6;Q05720", "ec_number_list": [], "go_molecular_function": "GO:0042910 xenobiotic transmembrane transporter activity;GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane", "go_biological_process": "GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P33335-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P33757-1", "uniprot_id": [ { "id": "SPO23_YEAST", "url": "https://www.uniprot.org/uniprot/P33757", "type": "external" } ], "mass": 59919.0, "length": 523, "protein_name": "Sporulation protein 23", "gene_name": "SPO23", "organism": "Yeast", "refseq_name": "Spo23p", "refseq_ac": [ { "id": "NP_009809", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009809", "type": "external" } ], "gene_names_uniprotkb": "SPO23; YBR1702", "gene_names_refseq": "SPO23", "protein_names_uniprotkb": "Sporulation protein 23", "protein_names_refseq": "Spo23p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR250W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15755922;17179081;24374639;7813418;8256522", "class_list": "", "function": "Regulates expression of PIS1., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQP6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0051321 meiotic cell cycle;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P33757-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P34228-1", "uniprot_id": [ { "id": "SEF1_YEAST", "url": "https://www.uniprot.org/uniprot/P34228", "type": "external" } ], "mass": 127992.0, "length": 1148, "protein_name": "Putative transcription factor SEF1", "gene_name": "SEF1", "organism": "Yeast", "refseq_name": "Sef1p", "refseq_ac": [ { "id": "NP_009487", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009487", "type": "external" } ], "gene_names_uniprotkb": "SEF1; YBL0501; YBL0526", "gene_names_refseq": "SEF1", "protein_names_uniprotkb": "Putative transcription factor SEF1; Suppressor of essential function protein 1; Suppressor protein SEF1", "protein_names_refseq": "Sef1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBL066C)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "18407956;19779198;20489023;20702584;21177495;23749301;24374639;32597660;33229814;33481703;33491328;33502312;7813418;8154187;9483797", "class_list": "", "function": "Putative transcription factor that seems to be involved in the sporulation process. Suppresses the lethal phenotype of RPM2 deletion., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 12, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 12, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 12, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 31, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 12, "binding_glycan_count": 0, "secondary_ac_list": "D6VPT5", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001216 DNA-binding transcription activator activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "P34228-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P34231-1", "uniprot_id": [ { "id": "YKS7_YEAST", "url": "https://www.uniprot.org/uniprot/P34231", "type": "external" } ], "mass": 81033.0, "length": 750, "protein_name": "Uncharacterized protein YKL187C", "gene_name": "", "organism": "Yeast", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein YKL187C", "protein_names_refseq": "", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL187C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12872131;14576278;17761666;19756047;19779198;24374639;33491328;8154185;8196765", "class_list": "", "function": "", "predicted_glycosites": 21, "predicted_n_glycosites": 21, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 21, "binding_glycan_count": 0, "secondary_ac_list": "D6VX13", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0051285 cell cortex of cell tip", "go_biological_process": "GO:0015909 long-chain fatty acid transport;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P34231-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P34234-1", "uniprot_id": [ { "id": "LOT5_YEAST", "url": "https://www.uniprot.org/uniprot/P34234", "type": "external" } ], "mass": 34326.0, "length": 306, "protein_name": "Protein LOT5", "gene_name": "LOT5", "organism": "Yeast", "refseq_name": "Lot5p", "refseq_ac": [ { "id": "NP_012738", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012738", "type": "external" } ], "gene_names_uniprotkb": "LOT5", "gene_names_refseq": "LOT5", "protein_names_uniprotkb": "Protein LOT5; Low temperature-responsive protein 5", "protein_names_refseq": "Lot5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL183W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11327734;14562095;14562106;24374639;8154185;8196765", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VX18", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005681 spliceosomal complex;GO:0034715 pICln-Sm protein complex", "go_biological_process": "GO:0000387 spliceosomal snRNP assembly;GO:0045292 mRNA cis splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P34234-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P34248-1", "uniprot_id": [ { "id": "SPP_YEAST", "url": "https://www.uniprot.org/uniprot/P34248", "type": "external" } ], "mass": 67525.0, "length": 587, "protein_name": "Intramembrane protease YPF1", "gene_name": "YPF1", "organism": "Yeast", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "YPF1; YKL450", "gene_names_refseq": "", "protein_names_uniprotkb": "Intramembrane protease YPF1; 3.4.23.-; Signal peptide peptidase; Yeast presenilin fold 1", "protein_names_refseq": "", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL100C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "16847258;24374639;25454947;8196765;8256524", "class_list": "", "function": "Catalyzes intramembrane proteolysis of endoplasmic reticulum (ER)-resident proteins (PubMed:25454947). Targets signal peptides (By similarity). Functions in endoplasmic reticulum-associated protein degradation (ERAD) of membrane proteins; ERAD comprises protein catabolic pathways that target ER-resident proteins for degradation by the cytoplasmic proteasome (PubMed:25454947). Involved in the ERAD-R branch together with DOA10 and DFM1; this pathway regulates protein levels in response to signal transduction (PubMed:25454947). Regulates the abundance of plasma membrane nutrient transporters in response to nutrient starvation (PubMed:25454947). Degrades the high-affinity zinc transporter ZRT1 in zinc-replete conditions (PubMed:25454947)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VXI7", "ec_number_list": [], "go_molecular_function": "GO:0042500 aspartic endopeptidase activity, intramembrane cleaving", "go_cellular_component": "GO:0098554 cytoplasmic side of endoplasmic reticulum membrane;GO:1990578 perinuclear endoplasmic reticulum membrane;GO:0098553 lumenal side of endoplasmic reticulum membrane", "go_biological_process": "GO:0009267 cellular response to starvation;GO:0051603 proteolysis involved in protein catabolic process;GO:0033619 membrane protein proteolysis;GO:0006465 signal peptide processing", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P34248-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P34250-1", "uniprot_id": [ { "id": "SEG2_YEAST", "url": "https://www.uniprot.org/uniprot/P34250", "type": "external" } ], "mass": 125593.0, "length": 1132, "protein_name": "Eisosome protein SEG2", "gene_name": "SEG2", "organism": "Yeast", "refseq_name": "Seg2p", "refseq_ac": [ { "id": "NP_012817", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012817", "type": "external" } ], "gene_names_uniprotkb": "SEG2; YKL459", "gene_names_refseq": "SEG2", "protein_names_uniprotkb": "Eisosome protein SEG2; Stability of eisosomes guaranteed protein 2", "protein_names_refseq": "Seg2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL105C)", "pathway_count": 1, "publication_count": 25, "publication_id_list": "14562106;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22106047;22218487;22869600;23749301;24374639;24909858;30516470;32597660;33229814;33481703;33491328;8109175;8196765", "class_list": "", "function": "Likely plays only a minor role in eisosome assembly., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 6, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 6, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 6, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 64, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VXI3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 3.3, "record_id": "P34250-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P35172-1", "uniprot_id": [ { "id": "TREB_YEAST", "url": "https://www.uniprot.org/uniprot/P35172", "type": "external" } ], "mass": 89679.0, "length": 780, "protein_name": "Probable trehalase", "gene_name": "NTH2", "organism": "Yeast", "refseq_name": "alpha,alpha-trehalase NTH2", "refseq_ac": [ { "id": "NP_009555", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009555", "type": "external" } ], "gene_names_uniprotkb": "NTH2; YBR0106", "gene_names_refseq": "NTH2", "protein_names_uniprotkb": "Probable trehalase; 3.2.1.28; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase", "protein_names_refseq": "alpha,alpha-trehalase NTH2", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR001C)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "14562106;17287358;17563356;18407956;19779198;20702584;23749301;24374639;30516470;32597660;33481703;33491328;7730323;7813418;8091860", "class_list": "glycogene;glycosylhydrolase", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQ02", "ec_number_list": [ { "id": "3.2.1.28", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.28", "type": "external" } ], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0004555 alpha,alpha-trehalase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0005993 trehalose catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P35172-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.10100", "kg_view_protein": true }, { "uniprot_canonical_ac": "P35195-1", "uniprot_id": [ { "id": "ECM15_YEAST", "url": "https://www.uniprot.org/uniprot/P35195", "type": "external" } ], "mass": 11518.0, "length": 104, "protein_name": "UPF0045 thiamine-binding protein family member ECM15", "gene_name": "ECM15", "organism": "Yeast", "refseq_name": "Ecm15p", "refseq_ac": [ { "id": "NP_009554", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009554", "type": "external" } ], "gene_names_uniprotkb": "ECM15; YBL0105", "gene_names_refseq": "ECM15", "protein_names_uniprotkb": "UPF0045 thiamine-binding protein family member ECM15; Extracellular mutant protein 15", "protein_names_refseq": "Ecm15p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBL001C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12866058;14562095;14562106;24374639;33491328;7813418;8091860", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQ01", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P35195-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P35209-1", "uniprot_id": [ { "id": "SPT21_YEAST", "url": "https://www.uniprot.org/uniprot/P35209", "type": "external" } ], "mass": 84697.0, "length": 758, "protein_name": "Protein SPT21", "gene_name": "SPT21", "organism": "Yeast", "refseq_name": "Spt21p", "refseq_ac": [ { "id": "NP_013904", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013904", "type": "external" } ], "gene_names_uniprotkb": "SPT21; YM8010.09", "gene_names_refseq": "SPT21", "protein_names_uniprotkb": "Protein SPT21", "protein_names_refseq": "Spt21p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR179W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "17287358;18407956;19684113;19779198;23749301;24374639;33481703;33491328;8138180;9169872", "class_list": "", "function": "Required for normal transcription at a number of loci in yeast., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W002", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0031509 subtelomeric heterochromatin formation;GO:0006357 regulation of transcription by RNA polymerase II;GO:0000183 rDNA heterochromatin formation;GO:0030466 silent mating-type cassette heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P35209-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P35724-1", "uniprot_id": [ { "id": "MNR2_YEAST", "url": "https://www.uniprot.org/uniprot/P35724", "type": "external" } ], "mass": 109737.0, "length": 969, "protein_name": "Manganese resistance protein MNR2", "gene_name": "MNR2", "organism": "Yeast", "refseq_name": "putative Mg(2+) transporter MNR2", "refseq_ac": [ { "id": "NP_012859", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012859", "type": "external" } ], "gene_names_uniprotkb": "MNR2", "gene_names_refseq": "MNR2", "protein_names_uniprotkb": "Manganese resistance protein MNR2", "protein_names_refseq": "putative Mg(2+) transporter MNR2", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL064W)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "14562106;16847258;17287358;17330950;17563356;18407956;19684113;19779198;20489023;20702584;21126336;21177495;22218487;23749301;24374639;27821475;30516470;32597660;33481703;33491328;34965436;8091862;8196765", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 46, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VXM3", "ec_number_list": [], "go_molecular_function": "GO:0015095 magnesium ion transmembrane transporter activity", "go_cellular_component": "GO:0000329 fungal-type vacuole membrane;GO:1990816 vacuole-mitochondrion membrane contact site", "go_biological_process": "GO:0010961 intracellular magnesium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P35724-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P36026-1", "uniprot_id": [ { "id": "UBP11_YEAST", "url": "https://www.uniprot.org/uniprot/P36026", "type": "external" } ], "mass": 82703.0, "length": 717, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11", "gene_name": "UBP11", "organism": "Yeast", "refseq_name": "ubiquitin-specific protease UBP11", "refseq_ac": [ { "id": "NP_013024", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013024", "type": "external" } ], "gene_names_uniprotkb": "UBP11", "gene_names_refseq": "UBP11", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 11; 3.4.19.12; Deubiquitinating enzyme 11; Ubiquitin thioesterase 11; Ubiquitin-specific-processing protease 11", "protein_names_refseq": "ubiquitin-specific protease UBP11", "tax_id": 559292, "disease": "", "pathway": " (sce:YKR098C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "22031224;23749301;24374639;32597660;33481703;33491328;8196765", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXF9", "ec_number_list": [], "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0031647 regulation of protein stability", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P36026-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P36029-1", "uniprot_id": [ { "id": "TPO5_YEAST", "url": "https://www.uniprot.org/uniprot/P36029", "type": "external" } ], "mass": 69243.0, "length": 618, "protein_name": "Polyamine transporter TPO5", "gene_name": "TPO5", "organism": "Yeast", "refseq_name": "Tpo5p", "refseq_ac": [ { "id": "NP_012747", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012747", "type": "external" } ], "gene_names_uniprotkb": "TPO5; YKL639", "gene_names_refseq": "TPO5", "protein_names_uniprotkb": "Polyamine transporter TPO5", "protein_names_refseq": "Tpo5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL174C)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "15668236;16847258;18407956;19779198;19795423;19823750;21126336;22814378;23749301;24374639;32597660;33481703;33491328;8091858;8196765", "class_list": "", "function": "Required for polyamine transport. Transports putrescine effectively and spermidine less effectively., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VX26", "ec_number_list": [], "go_molecular_function": "GO:0015185 gamma-aminobutyric acid transmembrane transporter activity;GO:0015203 polyamine transmembrane transporter activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0015812 gamma-aminobutyric acid transport;GO:0015846 polyamine transport", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P36029-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P36038-1", "uniprot_id": [ { "id": "CBT1_YEAST", "url": "https://www.uniprot.org/uniprot/P36038", "type": "external" } ], "mass": 31157.0, "length": 271, "protein_name": "Cytochrome b termination protein 1", "gene_name": "CBT1", "organism": "Yeast", "refseq_name": "Cbt1p", "refseq_ac": [ { "id": "NP_012714", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012714", "type": "external" } ], "gene_names_uniprotkb": "CBT1; SOC1", "gene_names_refseq": "CBT1; SOC1", "protein_names_uniprotkb": "Cytochrome b termination protein 1", "protein_names_refseq": "Cbt1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL208W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10101159;14562095;16118200;17322287;21177495;24374639;7851755;8196765;9339340", "class_list": "", "function": "Involved in 5'-end processing of mitochondrial COB, 15S rRNA, and RPM1 transcript. May also have a role in 3'-end processing of the COB pre-mRNA., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWZ5;Q6Q574", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006397 mRNA processing;GO:0048255 mRNA stabilization;GO:0006364 rRNA processing;GO:0017004 cytochrome complex assembly", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P36038-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P36044-1", "uniprot_id": [ { "id": "MNN4_YEAST", "url": "https://www.uniprot.org/uniprot/P36044", "type": "external" } ], "mass": 139381.0, "length": 1178, "protein_name": "Mannosyltransferase regulator 4", "gene_name": "MNN4", "organism": "Yeast", "refseq_name": "Mnn4p", "refseq_ac": [ { "id": "NP_012721", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012721", "type": "external" } ], "gene_names_uniprotkb": "MNN4; YKL200C", "gene_names_refseq": "MNN4; YKL200C", "protein_names_uniprotkb": "Mannosyltransferase regulator 4", "protein_names_refseq": "Mnn4p", "tax_id": 559292, "disease": "Fukuyama congenital muscular dystrophy (Disease Ontology:DOID:0050559); Walker-Warburg syndrome (Disease Ontology:DOID:0050560); muscular dystrophy-dystroglycanopathy type B1 (Disease Ontology:DOID:0050588); autosomal recessive limb-girdle muscular dystrophy type 2L (Disease Ontology:DOID:0110284); autosomal recessive limb-girdle muscular dystrophy type 2M (Disease Ontology:DOID:0110296); dilated cardiomyopathy 1B (Disease Ontology:DOID:0110443); dilated cardiomyopathy 1X (Disease Ontology:DOID:0110444); muscular dystrophy-dystroglycanopathy type B4 (Disease Ontology:DOID:0112379); muscular dystrophy (Disease Ontology:DOID:9884)", "pathway": " (sce:YKL201C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "15993632;24374639;28101612;30842360;8196765;9023541;9459307", "class_list": "", "function": "Golgi apparatus protein involved in N-glycan mannosylphosphorylation (PubMed:15993632, PubMed:28101612, PubMed:30842360, PubMed:9023541, PubMed:9459307). While MNN4 seems to have a regulatory role in N-glycan mannosylphosphorylation, a transferase activity of MNN4 cannot be ruled out (PubMed:15993632, PubMed:28101612, PubMed:30842360, PubMed:9023541, PubMed:9459307). Mediates mannosylphosphate transfer in both the core and outer chain portions of N-linked oligosaccharides (PubMed:9023541). Has partially redundant function with MNN14 (PubMed:28101612)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VX01;P36043;P89095", "ec_number_list": [], "go_molecular_function": "GO:0008047 enzyme activator activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0006493 protein O-linked glycosylation;GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P36044-1", "record_type": "protein", "filter_code": "0000000.0100111.010000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P36078-1", "uniprot_id": [ { "id": "HOT13_YEAST", "url": "https://www.uniprot.org/uniprot/P36078", "type": "external" } ], "mass": 13641.0, "length": 116, "protein_name": "Helper of Tim protein 13", "gene_name": "HOT13", "organism": "Yeast", "refseq_name": "Hot13p", "refseq_ac": [ { "id": "NP_012839", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012839", "type": "external" } ], "gene_names_uniprotkb": "HOT13", "gene_names_refseq": "HOT13", "protein_names_uniprotkb": "Helper of Tim protein 13", "protein_names_refseq": "Hot13p", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL084W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "15294910;17322287;22814378;24374639;33491328;8196765", "class_list": "", "function": "Required for the assembly or recycling of the small Tim proteins in the mitochondrial intermembrane, thereby participating in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Probably acts by facilitating the formation of disulfide bonds in small Tim proteins., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, 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"record_id": "P36090-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P36114-1", "uniprot_id": [ { "id": "YKR18_YEAST", "url": "https://www.uniprot.org/uniprot/P36114", "type": "external" } ], "mass": 81754.0, "length": 725, "protein_name": "IML2-like protein YKR018C", "gene_name": "", "organism": "Yeast", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_012943", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012943", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "IML2-like protein YKR018C", "protein_names_refseq": "uncharacterized protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YKR018C)", "pathway_count": 1, "publication_count": 22, "publication_id_list": 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"0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P36137-1", "uniprot_id": [ { "id": "UIP5_YEAST", "url": "https://www.uniprot.org/uniprot/P36137", "type": "external" } ], "mass": 50981.0, "length": 443, "protein_name": "Protein UIP5", "gene_name": "UIP5", "organism": "Yeast", "refseq_name": "Uip5p", "refseq_ac": [ { "id": "NP_012970", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012970", "type": "external" } ], "gene_names_uniprotkb": "UIP5", "gene_names_refseq": "UIP5", "protein_names_uniprotkb": "Protein UIP5; ULP1-interacting protein 5", "protein_names_refseq": "Uip5p", "tax_id": 559292, "disease": "autosomal dominant intellectual developmental disorder 69 (Disease Ontology:DOID:0061042); autosomal recessive intellectual developmental disorder 52 (Disease Ontology:DOID:0081215); factor XIII deficiency (Disease Ontology:DOID:2211); factor V deficiency (Disease Ontology:DOID:2216)", "pathway": " (sce:YKR044W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562106;16847258;17322287;23749301;24374639;32597660;33481703;33491328;8196765", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, 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"url": "https://www.uniprot.org/uniprot/P36139", "type": "external" } ], "mass": 31246.0, "length": 283, "protein_name": "Protein PET10", "gene_name": "PET10", "organism": "Yeast", "refseq_name": "Pln1p", "refseq_ac": [ { "id": "NP_012972", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012972", "type": "external" } ], "gene_names_uniprotkb": "PET10", "gene_names_refseq": "PET10; PLN1", "protein_names_uniprotkb": "Protein PET10; Petite colonies protein 10", "protein_names_refseq": "Pln1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YKR046C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10515935;14562106;19779198;20702584;23749301;24374639;33229814;33481703;33491328;8196765", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, 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"reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VXG6", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005774 vacuolar membrane", "go_biological_process": "GO:0055085 transmembrane transport;GO:1903826 L-arginine transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P36172-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P36973-1", "uniprot_id": [ { "id": "APT2_YEAST", "url": "https://www.uniprot.org/uniprot/P36973", "type": "external" } ], "mass": 19986.0, "length": 181, "protein_name": "Adenine phosphoribosyltransferase 2", "gene_name": "APT2", "organism": "Yeast", "refseq_name": "adenine phosphoribosyltransferase APT2", "refseq_ac": [ { "id": "NP_010729", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010729", "type": "external" } ], "gene_names_uniprotkb": "APT2; D9461.27", "gene_names_refseq": "APT2", "protein_names_uniprotkb": "Adenine phosphoribosyltransferase 2; 2.4.2.7; APRT 2", "protein_names_refseq": "adenine phosphoribosyltransferase APT2", "tax_id": 559292, "disease": "adenine phosphoribosyltransferase deficiency (Disease Ontology:DOID:0060350); Lesch-Nyhan syndrome (Disease Ontology:DOID:1919); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (sce:YDR441C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;22814378;24374639;33491328;7941749;9169867;9864350", "class_list": "", "function": "Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. May lack catalytic activity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q04090", "ec_number_list": [ { "id": "2.4.2.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.7", "type": "external" } ], "go_molecular_function": "GO:0016208 AMP binding;GO:0002055 adenine binding;GO:0003999 adenine phosphoribosyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0044209 AMP salvage;GO:0006166 purine ribonucleoside salvage;GO:0006168 adenine salvage", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P36973-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P37261-1", "uniprot_id": [ { "id": "FRM2_YEAST", "url": "https://www.uniprot.org/uniprot/P37261", "type": "external" } ], "mass": 21232.0, "length": 193, "protein_name": "nitroreductase FRM2", "gene_name": "FRM2", "organism": "Yeast", "refseq_name": "type II nitroreductase", "refseq_ac": [ { "id": "NP_009904", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009904", "type": "external" } ], "gene_names_uniprotkb": "FRM2; YCLX08C; YCLX8C", "gene_names_refseq": "FRM2; YCLX08C", "protein_names_uniprotkb": "nitroreductase FRM2; 1.7.1.9; Fatty acid repression mutant protein 2", "protein_names_refseq": "type II nitroreductase", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL026C-A)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "14562095;1574125;16506856;18407956;18627600;19904831;22687599;24374639;25864423;33481703;33491328;8313894;8701605", "class_list": "", "function": "Type II nitroreductase, able to reduce 4-nitroquinoline N-oxide (4-NQO) into 4-aminoquinoline-N-oxide (4-AQO) via 4-hydroxyaminoquinoline (4-HAQO), using NADH as reductant (PubMed:22687599, PubMed:25864423). involved in the oxidative stress response (PubMed:19904831). Plays a possible role in the metal stress response (PubMed:18627600). Involved in negative regulation of fatty acid metabolism (PubMed:8701605)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQZ0;Q8NIM8", "ec_number_list": [ { "id": "1.7.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:1.7.1.9", "type": "external" } ], "go_molecular_function": "GO:0016651 oxidoreductase activity, acting on NAD(P)H;GO:0050465 nitroquinoline-N-oxide reductase [NAD(P)H] activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0045922 negative regulation of fatty acid metabolic process;GO:0006631 fatty acid metabolic process;GO:0034599 cellular response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P37261-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P37267-1", "uniprot_id": [ { "id": "CBP4_YEAST", "url": "https://www.uniprot.org/uniprot/P37267", "type": "external" } ], "mass": 17532.0, "length": 147, "protein_name": "Assembly factor CBP4", "gene_name": "CBP4", "organism": "Yeast", "refseq_name": "Cbp4p", "refseq_ac": [ { "id": "NP_011690", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011690", "type": "external" } ], "gene_names_uniprotkb": "CBP4; G7122", "gene_names_refseq": "CBP4", "protein_names_uniprotkb": "Assembly factor CBP4; Cytochrome b mRNA-processing protein 4", "protein_names_refseq": "Cbp4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR174C); (R-SCE-9865878)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "14562095;14562106;14576278;15759116;17322287;24374639;8063753;9169869", "class_list": "", "function": "Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUV8;Q6TQT9;Q6TQU0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0034551 mitochondrial respiratory chain complex III assembly", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P37267-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P37293-1", "uniprot_id": [ { "id": "NAT2_YEAST", "url": "https://www.uniprot.org/uniprot/P37293", "type": "external" } ], "mass": 32804.0, "length": 288, "protein_name": "Putative N-terminal acetyltransferase 2", "gene_name": "NAT2", "organism": "Yeast", "refseq_name": "Nat2p", "refseq_ac": [ { "id": "NP_011663", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011663", "type": "external" } ], "gene_names_uniprotkb": "NAT2; G6630", "gene_names_refseq": "NAT2", "protein_names_uniprotkb": "Putative N-terminal acetyltransferase 2; 2.3.1.-; Amino-terminal, alpha-amino, acetyltransferase 2", "protein_names_refseq": "Nat2p", "tax_id": 559292, "disease": "systemic lupus erythematosus (Disease Ontology:DOID:9074)", "pathway": " (sce:YGR147C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;24374639;8175741;8585325;9169869", "class_list": "", "function": "Maybe involved in N-terminal acetylation of proteins. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUS8", "ec_number_list": [], "go_molecular_function": "GO:0016746 acyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0017196 N-terminal peptidyl-methionine acetylation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P37293-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P37304-1", "uniprot_id": [ { "id": "PAM1_YEAST", "url": "https://www.uniprot.org/uniprot/P37304", "type": "external" } ], "mass": 92872.0, "length": 830, "protein_name": "Protein PAM1", "gene_name": "PAM1", "organism": "Yeast", "refseq_name": "Pam1p", "refseq_ac": [ { "id": "NP_010537", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010537", "type": "external" } ], "gene_names_uniprotkb": "PAM1; YD8419.18; YD9320A.01", "gene_names_refseq": "PAM1", "protein_names_uniprotkb": "Protein PAM1", "protein_names_refseq": "Pam1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR251W)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "11875433;14562106;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;22218487;23749301;24374639;30516470;32597660;33229814;33481703;33491328;8106383;9169867", "class_list": "", "function": "Not known. It is a suppressor of protein phosphatase 2A depletion., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 17, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 17, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 17, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 49, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 16, "binding_glycan_count": 0, "secondary_ac_list": "D6VSN1;Q03789", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005933 cellular bud;GO:0005934 cellular bud tip;GO:0005935 cellular bud neck", "go_biological_process": "GO:0007124 pseudohyphal growth", "synthesized_glycan_count": 0, "hit_score": 4.2, "record_id": "P37304-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38061-1", "uniprot_id": [ { "id": "RL32_YEAST", "url": "https://www.uniprot.org/uniprot/P38061", "type": "external" } ], "mass": 14771.0, "length": 130, "protein_name": "Large ribosomal subunit protein eL32", "gene_name": "RPL32", "organism": "Yeast", "refseq_name": "60S ribosomal protein eL32 RPL32", "refseq_ac": [ { "id": "NP_009460", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009460", "type": "external" } ], "gene_names_uniprotkb": "RPL32; YBL0838", "gene_names_refseq": "RPL32", "protein_names_uniprotkb": "Large ribosomal subunit protein eL32; 60S ribosomal protein L32", "protein_names_refseq": "60S ribosomal protein eL32 RPL32", "tax_id": 559292, "disease": "", "pathway": " (sce:YBL092W); (R-SCE-156827); (R-SCE-1799339); (R-SCE-72689); (R-SCE-72706); (R-SCE-975956); (R-SCE-975957); (R-SCE-9954709); (R-SCE-9954714)", "pathway_count": 9, "publication_count": 22, "publication_id_list": "10601260;11701127;14976550;17244705;17287358;17322287;18407956;19779198;19795423;19823750;21109664;21126336;22096102;23749301;24374639;24524803;32597660;33481703;33491328;7502586;7813418;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A2TBM1;D6VPR1", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P38061-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38073-1", "uniprot_id": [ { "id": "EDS1_YEAST", "url": "https://www.uniprot.org/uniprot/P38073", "type": "external" } ], "mass": 103397.0, "length": 919, "protein_name": "Transcriptional regulatory protein EDS1", "gene_name": "EDS1", "organism": "Yeast", "refseq_name": "Eds1p", "refseq_ac": [ { "id": "NP_009589", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009589", "type": "external" } ], "gene_names_uniprotkb": "EDS1; YBR0318", "gene_names_refseq": "EDS1", "protein_names_uniprotkb": "Transcriptional regulatory protein EDS1; Expression dependent on SLT2 protein 1", "protein_names_refseq": "Eds1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR033W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "19111667;19779198;24374639;33491328;7813418;8091864", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQ33", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P38073-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38079-1", "uniprot_id": [ { "id": "YRO2_YEAST", "url": "https://www.uniprot.org/uniprot/P38079", "type": "external" } ], "mass": 38720.0, "length": 344, "protein_name": "Protein YRO2", "gene_name": "YRO2", "organism": "Yeast", "refseq_name": "Yro2p", "refseq_ac": [ { "id": "NP_009610", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009610", "type": "external" } ], "gene_names_uniprotkb": "YRO2; 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YBR0833", "gene_names_refseq": "YMC2", "protein_names_uniprotkb": "Carrier protein YMC2, mitochondrial", "protein_names_refseq": "organic acid transporter", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR104W); (R-SCE-70635)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "14562106;17322287;24374639;7813418;7900426", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQA3", "ec_number_list": [], "go_molecular_function": "GO:0015187 glycine transmembrane transporter activity;GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006839 mitochondrial transport;GO:0055085 transmembrane transport;GO:1990575 mitochondrial L-ornithine transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P38087-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38089-1", "uniprot_id": [ { "id": "PP2C4_YEAST", "url": "https://www.uniprot.org/uniprot/P38089", "type": "external" } ], "mass": 44176.0, "length": 393, "protein_name": "Protein phosphatase 2C homolog 4", "gene_name": "PTC4", "organism": "Yeast", "refseq_name": "type 2C protein phosphatase PTC4", "refseq_ac": [ { "id": "NP_009683", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009683", "type": "external" } ], "gene_names_uniprotkb": "PTC4; GCT1; YBR0921", "gene_names_refseq": "GCT1; PTC4", "protein_names_uniprotkb": "Protein phosphatase 2C homolog 4; 3.1.3.16; PP2C-4", "protein_names_refseq": "type 2C protein phosphatase PTC4", "tax_id": 559292, "disease": "asthma (Disease Ontology:DOID:2841)", "pathway": " (sce:YBR125C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;19779198;20489023;24374639;7813418;7900426", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQC2", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.43", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.43", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction;GO:0006470 protein dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P38089-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38120-1", "uniprot_id": [ { "id": "RT09_YEAST", "url": "https://www.uniprot.org/uniprot/P38120", "type": "external" } ], "mass": 31925.0, "length": 278, "protein_name": "Small ribosomal subunit protein uS9m", "gene_name": "MRPS9", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein uS9m MRPS9", "refseq_ac": [ { "id": "NP_009704", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009704", "type": "external" } ], "gene_names_uniprotkb": "MRPS9; YBR1123", "gene_names_refseq": "MRPS9; uS9m", "protein_names_uniprotkb": "Small ribosomal subunit protein uS9m; 37S ribosomal protein S9, mitochondrial", "protein_names_refseq": "mitochondrial 37S ribosomal protein uS9m MRPS9", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR146W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11278769;12392552;14576278;24374639;25609543;28154081;7813418;8536310", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VQE1", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P38120-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38124-1", "uniprot_id": [ { "id": "FLR1_YEAST", "url": "https://www.uniprot.org/uniprot/P38124", "type": "external" } ], "mass": 61629.0, "length": 548, "protein_name": "Fluconazole resistance protein 1", "gene_name": "FLR1", "organism": "Yeast", "refseq_name": "Flr1p", "refseq_ac": [ { "id": "NP_009562", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009562", "type": "external" } ], "gene_names_uniprotkb": "FLR1; YBR0120", "gene_names_refseq": "FLR1", "protein_names_uniprotkb": "Fluconazole resistance protein 1", "protein_names_refseq": "Flr1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR008C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "24374639;33491328;7813418;9235926", "class_list": "", "function": "Probable efflux transporter. Confers resistance to the azole derivative fluconazole (FCZ)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQ09", "ec_number_list": [], "go_molecular_function": "GO:0015244 fluconazole transmembrane transporter activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:1990961 xenobiotic detoxification by transmembrane export across the plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P38124-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38141-1", "uniprot_id": [ { "id": "THI2_YEAST", "url": "https://www.uniprot.org/uniprot/P38141", "type": "external" } ], "mass": 51823.0, "length": 450, "protein_name": "Thiamine biosynthesis regulatory protein", "gene_name": "THI2", "organism": "Yeast", "refseq_name": "Thi2p", "refseq_ac": [ { "id": "NP_009799", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009799", "type": "external" } ], "gene_names_uniprotkb": "THI2; PHO6; YBR1624", "gene_names_refseq": "PHO6; THI2", "protein_names_uniprotkb": "Thiamine biosynthesis regulatory protein", "protein_names_refseq": "Thi2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR240C)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "24374639;7813418", "class_list": "", "function": "Positive regulator of thiamine biosynthesis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQN6", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0090180 positive regulation of thiamine biosynthetic process;GO:0009228 thiamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P38141-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38142-1", "uniprot_id": [ { "id": "YB91_YEAST", "url": "https://www.uniprot.org/uniprot/P38142", "type": "external" } ], "mass": 53526.0, "length": 488, "protein_name": "Probable metabolite transport protein YBR241C", "gene_name": "YBR1625", "organism": "Yeast", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "YBR1625", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable metabolite transport protein YBR241C", "protein_names_refseq": "", "tax_id": 559292, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); myelomeningocele (Disease Ontology:DOID:0060326); abdominal obesity-metabolic syndrome (Disease Ontology:DOID:0060611); glucose transporter type 1 deficiency syndrome (Disease Ontology:DOID:0070560); glucose transporter type 1 deficiency syndrome 1 (Disease Ontology:DOID:0070561); Fanconi-Bickel syndrome (Disease Ontology:DOID:0070562); dystonia 9 (Disease Ontology:DOID:0090044); glucose transporter type 1 deficiency syndrome 2 (Disease Ontology:DOID:0090045); Hirschsprung's disease (Disease Ontology:DOID:10487); pre-eclampsia (Disease Ontology:DOID:10591); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); hypothyroidism (Disease Ontology:DOID:1459); childhood absence epilepsy (Disease Ontology:DOID:1825); hyperuricemia (Disease Ontology:DOID:1920); nephroblastoma (Disease Ontology:DOID:2154); hemangioma (Disease Ontology:DOID:255); glycogen storage disease (Disease Ontology:DOID:2747); acanthosis nigricans (Disease Ontology:DOID:3138); coronary artery disease (Disease Ontology:DOID:3393); middle cerebral artery infarction (Disease Ontology:DOID:3525); insulinoma (Disease Ontology:DOID:3892); gastrinoma (Disease Ontology:DOID:5577); congestive heart failure (Disease Ontology:DOID:6000); pulmonary hypertension (Disease Ontology:DOID:6432); cataract (Disease Ontology:DOID:83); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YBR241C); (R-SCE-189200); (R-SCE-196836); (R-SCE-422356); (R-SCE-5653890); (R-SCE-6798695); (R-SCE-8981373)", "pathway_count": 7, "publication_count": 5, "publication_id_list": "14562095;16847258;17322287;24374639;7813418", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 29, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VQN7;Q6B2Y5", "ec_number_list": [], "go_molecular_function": "GO:0015149 hexose transmembrane transporter activity;GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0055085 transmembrane transport;GO:0015749 monosaccharide transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P38142-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38145-1", "uniprot_id": [ { "id": "RISA_YEAST", "url": "https://www.uniprot.org/uniprot/P38145", "type": "external" } ], "mass": 26196.0, "length": 238, "protein_name": "Riboflavin synthase", "gene_name": "RIB5", "organism": "Yeast", "refseq_name": "riboflavin synthase", "refseq_ac": [ { "id": "NP_009815", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009815", "type": "external" } ], "gene_names_uniprotkb": "RIB5; YBR1724", "gene_names_refseq": "RIB5", "protein_names_uniprotkb": "Riboflavin synthase; 2.5.1.9; RS", "protein_names_refseq": "riboflavin synthase", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR256C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;18407956;24374639;33491328;7813418;7814407;8465606", "class_list": "", "function": "Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQQ3", "ec_number_list": [ { "id": "2.5.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.9", "type": "external" } ], "go_molecular_function": "GO:0004746 riboflavin synthase activity", "go_cellular_component": "", "go_biological_process": "GO:0009231 riboflavin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P38145-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38151-1", "uniprot_id": [ { "id": "PBP2_YEAST", "url": "https://www.uniprot.org/uniprot/P38151", "type": "external" } ], "mass": 45782.0, "length": 413, "protein_name": "PAB1-binding protein 2", "gene_name": "PBP2", "organism": "Yeast", "refseq_name": "telomere maintenance protein PBP2", "refseq_ac": [ { "id": "NP_009792", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009792", "type": "external" } ], "gene_names_uniprotkb": "PBP2; YBR1531", "gene_names_refseq": "HEK1; PBP2", "protein_names_uniprotkb": "PAB1-binding protein 2", "protein_names_refseq": "telomere maintenance protein PBP2", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR233W); (R-SCE-72203)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "14562106;15665377;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21177495;24374639;32597660;33481703;33491328;7813418;9819425", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQM8", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000723 telomere maintenance", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P38151-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38152-1", "uniprot_id": [ { "id": "TXTP_YEAST", "url": "https://www.uniprot.org/uniprot/P38152", "type": "external" } ], "mass": 32173.0, "length": 299, "protein_name": "Tricarboxylate transport protein", "gene_name": "CTP1", "organism": "Yeast", "refseq_name": "Ctp1p", "refseq_ac": [ { "id": "NP_009850", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009850", "type": "external" } ], "gene_names_uniprotkb": "CTP1; YBR2039", "gene_names_refseq": "CTP1", "protein_names_uniprotkb": "Tricarboxylate transport protein; CTP; Citrate transport protein", "protein_names_refseq": "Ctp1p", "tax_id": 559292, "disease": "2-hydroxyglutaric aciduria (Disease Ontology:DOID:0050573); chromosome 22q11.2 deletion syndrome, distal (Disease Ontology:DOID:0060413); combined D-2- and L-2-hydroxyglutaric aciduria (Disease Ontology:DOID:0111619); DiGeorge syndrome (Disease Ontology:DOID:11198); congenital myasthenic syndrome (Disease Ontology:DOID:3635); mitochondrial metabolism disease (Disease Ontology:DOID:700)", "pathway": " (sce:YBR291C); (R-SCE-428643)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "21126336;24374639;7813418;7876161;8091861", "class_list": "", "function": "Mitochondrial electroneutral antiporter that exports citrate from the mitochondria into the cytosol in exchange for malate (PubMed:7876161). Substrate exchange across the membrane occurs consecutively with one substrate being transported first, then dissociating from the substrate binding site before the second substrate binds for transport in the opposite direction (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQT6;Q02507", "ec_number_list": [], "go_molecular_function": "GO:0015297 antiporter activity;GO:0005371 tricarboxylate secondary active transmembrane transporter activity;GO:0071913 citrate secondary active transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0055085 transmembrane transport;GO:0006843 mitochondrial citrate transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P38152-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38156-1", "uniprot_id": [ { "id": "MAL31_YEAST", "url": "https://www.uniprot.org/uniprot/P38156", "type": "external" } ], "mass": 68263.0, "length": 614, "protein_name": "Maltose permease MAL31", "gene_name": "MAL31", "organism": "Yeast", "refseq_name": "maltose permease", "refseq_ac": [ { "id": "NP_009857", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009857", "type": "external" } ], "gene_names_uniprotkb": "MAL31; MAL3T; YBR2116", "gene_names_refseq": "MAL31", "protein_names_uniprotkb": "Maltose permease MAL31; Maltose transport protein MAL31", "protein_names_refseq": "maltose permease", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR298C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12210897;16088872;16847258;17322287;24374639;7483839;7813418", "class_list": "", "function": "High-affinity uptake of maltose and maltotriose. Also transports turanose but not alpha-methylglucoside, melezitose or trehalose., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQU3;Q3SCJ3", "ec_number_list": [], "go_molecular_function": "GO:0005351 carbohydrate:proton symporter activity;GO:0005352 alpha-glucoside:proton symporter activity", "go_cellular_component": "GO:0016020 membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0008643 carbohydrate transport;GO:0000023 maltose metabolic process;GO:0000017 alpha-glucoside transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P38156-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38157-1", "uniprot_id": [ { "id": "MAL33_YEAST", "url": "https://www.uniprot.org/uniprot/P38157", "type": "external" } ], "mass": 54194.0, "length": 468, "protein_name": "Maltose fermentation regulatory protein MAL33", "gene_name": "MAL33", "organism": "Yeast", "refseq_name": "transcription factor MAL33", "refseq_ac": [ { "id": "NP_009856", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009856", "type": "external" } ], "gene_names_uniprotkb": "MAL33; MAL3R; YBR2115", "gene_names_refseq": "MAL33", "protein_names_uniprotkb": "Maltose fermentation regulatory protein MAL33", "protein_names_refseq": "transcription factor MAL33", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR297W)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "17322287;24374639;7813418", "class_list": "", "function": "Regulates the coordinate transcription of structural MAL3S (maltase) and MAL3T (maltose permease) genes., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQU2", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0000023 maltose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P38157-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38172-1", "uniprot_id": [ { "id": "MRX3_YEAST", "url": "https://www.uniprot.org/uniprot/P38172", "type": "external" } ], "mass": 30545.0, "length": 270, "protein_name": "MIOREX complex component 3", "gene_name": "MRX3", "organism": "Yeast", "refseq_name": "Mrx3p", "refseq_ac": [ { "id": "NP_009457", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009457", "type": "external" } ], "gene_names_uniprotkb": "MRX3; YBL0835", "gene_names_refseq": "MRX3", "protein_names_uniprotkb": "MIOREX complex component 3; Mitochondrial organization of gene expression protein 3", "protein_names_refseq": "Mrx3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBL095W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;16823961;17322287;24374639;25683707;7502586;7813418", "class_list": "", "function": "Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VPQ9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P38172-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38176-1", "uniprot_id": [ { "id": "AVT5_YEAST", "url": "https://www.uniprot.org/uniprot/P38176", "type": "external" } ], "mass": 50892.0, "length": 459, "protein_name": "Vacuolar amino acid transporter 5", "gene_name": "AVT5", "organism": "Yeast", "refseq_name": "amino acid transporter", "refseq_ac": [ { "id": "NP_009464", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009464", "type": "external" } ], "gene_names_uniprotkb": "AVT5; YBL0703", "gene_names_refseq": "AVT5", "protein_names_uniprotkb": "Vacuolar amino acid transporter 5", "protein_names_refseq": "amino acid transporter", "tax_id": 559292, "disease": "hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (sce:YBL089W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11274162;12748633;24374639;7502586;7813418", "class_list": "", "function": "Probable amino acid transporter of unknown specificity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPR5", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015194 L-serine transmembrane transporter activity;GO:0015189 L-lysine transmembrane transporter activity;GO:0005290 L-histidine transmembrane transporter activity;GO:0005302 L-tyrosine transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0055085 transmembrane transport;GO:0003333 amino acid transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P38176-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38197-1", "uniprot_id": [ { "id": "PLPHP_YEAST", "url": "https://www.uniprot.org/uniprot/P38197", "type": "external" } ], "mass": 29123.0, "length": 257, "protein_name": "Pyridoxal phosphate homeostasis protein", "gene_name": "YBL0413", "organism": "Yeast", "refseq_name": "pyridoxal phosphate homeostasis protein", "refseq_ac": [ { "id": "NP_009517", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009517", "type": "external" } ], "gene_names_uniprotkb": "YBL0413", "gene_names_refseq": "", "protein_names_uniprotkb": "Pyridoxal phosphate homeostasis protein; PLP homeostasis protein", "protein_names_refseq": "pyridoxal phosphate homeostasis protein", "tax_id": 559292, "disease": "early-onset vitamin B6-dependent epilepsy 1 (Disease Ontology:DOID:0080769)", "pathway": " (sce:YBL036C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12499548;14562095;14562106;17322287;22218487;22814378;24374639;33491328;7813418;7871888", "class_list": "", "function": "Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPW3;Q6B256", "ec_number_list": [], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0042816 vitamin B6 metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P38197-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38206-1", "uniprot_id": [ { "id": "RFT1_YEAST", "url": "https://www.uniprot.org/uniprot/P38206", "type": "external" } ], "mass": 66211.0, "length": 574, "protein_name": "Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1", "gene_name": "RFT1", "organism": "Yeast", "refseq_name": "glycolipid translocation protein", "refseq_ac": [ { "id": "NP_009533", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009533", "type": "external" } ], "gene_names_uniprotkb": "RFT1; YBL0442", "gene_names_refseq": "RFT1", "protein_names_uniprotkb": "Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1; Requiring fifty-three protein 1", "protein_names_refseq": "glycolipid translocation protein", "tax_id": 559292, "disease": "congenital disorder of glycosylation type I (Disease Ontology:DOID:0050570); congenital disorder of glycosylation In (Disease Ontology:DOID:0080566); cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YBL020W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11807558;16847258;18668045;22814378;24374639;2832732;7673248;7813418", "class_list": "", "function": "Intramembrane glycolipid transporter that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. RFT1 could mediate the translocation of the cytosolically oriented intermediate DolPP-GlcNAc2Man5, produced by ALG11, into the ER lumen where dolichol-linked oligosaccharides assembly continues (PubMed:11807558). However, the intramembrane lipid transporter activity could not be confirmed in vitro (PubMed:18668045)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPY0;Q05814", "ec_number_list": [], "go_molecular_function": "GO:0034202 glycolipid floppase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006488 dolichol-linked oligosaccharide biosynthetic process;GO:0006487 protein N-linked glycosylation;GO:0034203 glycolipid translocation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P38206-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38229-1", "uniprot_id": [ { "id": "GIP1_YEAST", "url": "https://www.uniprot.org/uniprot/P38229", "type": "external" } ], "mass": 73355.0, "length": 639, "protein_name": "GLC7-interacting protein 1", "gene_name": "GIP1", "organism": "Yeast", "refseq_name": "protein phosphatase regulator GIP1", "refseq_ac": [ { "id": "NP_009601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009601", "type": "external" } ], "gene_names_uniprotkb": "GIP1; YBR0420", "gene_names_refseq": "GIP1", "protein_names_uniprotkb": "GLC7-interacting protein 1", "protein_names_refseq": "protein phosphatase regulator GIP1", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR045C)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "17322287;24374639;7813418", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VQ45", "ec_number_list": [], "go_molecular_function": "GO:0019888 protein phosphatase regulator activity;GO:0008157 protein phosphatase 1 binding", "go_cellular_component": "GO:0000164 protein phosphatase type 1 complex;GO:0005628 prospore membrane", "go_biological_process": "GO:0030476 ascospore wall assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P38229-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38230-1", "uniprot_id": [ { "id": "QOR_YEAST", "url": "https://www.uniprot.org/uniprot/P38230", "type": "external" } ], "mass": 37019.0, "length": 334, "protein_name": "Zeta-crystallin", "gene_name": "ZTA1", "organism": "Yeast", "refseq_name": "NADPH:quinone reductase", "refseq_ac": [ { "id": "NP_009602", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009602", "type": "external" } ], "gene_names_uniprotkb": "ZTA1; YBR0421", "gene_names_refseq": "ZTA1", "protein_names_uniprotkb": "Zeta-crystallin; 1.6.5.5; NADPH:quinone reductase; Quinone oxidoreductase", "protein_names_refseq": "NADPH:quinone reductase", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR046C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "17322287;17497241;21820057;24374639;7813418", "class_list": "", "function": "Multifunctional crystallin endowed with unrelated mRNA stabilization and enzymatic oxidoreductase activities (PubMed:17497241, PubMed:21820057). Binds (AU)-rich elements (ARE) in the 3'-UTR of target mRNA to enhance their stability (PubMed:17497241). Beside its mRNA stabilization activity, also catalyzes the reduction of orthoquinones such as 1,2-naphthoquinone or 9,10-phenanthrenequinone in the presence of NADPH in vitro and could be involved in the detoxification of xenobiotics and protection against oxidative stress (PubMed:17497241, PubMed:21820057)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 10, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQ46", "ec_number_list": [ { "id": "1.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.5.5", "type": "external" } ], "go_molecular_function": "GO:0032440 2-alkenal reductase [NAD(P)H] activity;GO:0008270 zinc ion binding;GO:0003960 quinone reductase (NADPH) activity;GO:0035925 mRNA 3'-UTR AU-rich region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0034599 cellular response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P38230-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38234-1", "uniprot_id": [ { "id": "RFS1_YEAST", "url": "https://www.uniprot.org/uniprot/P38234", "type": "external" } ], "mass": 22921.0, "length": 210, "protein_name": "Protein RFS1", "gene_name": "RFS1", "organism": "Yeast", "refseq_name": "flavodoxin-like fold family protein", "refseq_ac": [ { "id": "NP_009608", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009608", "type": "external" } ], "gene_names_uniprotkb": "RFS1; YBR0505", "gene_names_refseq": "RFS1", "protein_names_uniprotkb": "Protein RFS1; RAD55 suppressor protein 1", "protein_names_refseq": "flavodoxin-like fold family protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR052C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;16782999;17322287;19064668;24374639;7597852;7813418", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQ51", "ec_number_list": [], "go_molecular_function": "GO:0016491 oxidoreductase activity;GO:0010181 FMN binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0045121 membrane raft;GO:0032126 eisosome", "go_biological_process": "GO:0160020 positive regulation of ferroptosis", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P38234-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38271-1", "uniprot_id": [ { "id": "OPY1_YEAST", "url": "https://www.uniprot.org/uniprot/P38271", "type": "external" } ], "mass": 37740.0, "length": 328, "protein_name": "Pleckstrin homology domain protein OPY1", "gene_name": "OPY1", "organism": "Yeast", "refseq_name": "Opy1p", "refseq_ac": [ { "id": "NP_009687", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009687", "type": "external" } ], "gene_names_uniprotkb": "OPY1; YBR1004", "gene_names_refseq": "OPY1", "protein_names_uniprotkb": "Pleckstrin homology domain protein OPY1; Overproduction-induced pheromone-resistant yeast protein 1", "protein_names_refseq": "Opy1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR129C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562106;19779198;22562153;23749301;24374639;33491328;7813418;8091856;9383053", "class_list": "", "function": "Binds phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2/PIP2) at the cell membrane (PubMed:22562153). Negatively regulates the activity of phosphatidylinositol 4-phosphate 5-kinase MSS4 (PubMed:22562153)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQC6", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0043325 phosphatidylinositol-3,4-bisphosphate binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005886 plasma membrane", "go_biological_process": "GO:1902647 negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P38271-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38281-1", "uniprot_id": [ { "id": "APD1_YEAST", "url": "https://www.uniprot.org/uniprot/P38281", "type": "external" } ], "mass": 35759.0, "length": 316, "protein_name": "Actin patches distal protein 1", "gene_name": "APD1", "organism": "Yeast", "refseq_name": "Apd1p", "refseq_ac": [ { "id": "NP_009709", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009709", "type": "external" } ], "gene_names_uniprotkb": "APD1; YBR1201", "gene_names_refseq": "APD1", "protein_names_uniprotkb": "Actin patches distal protein 1", "protein_names_refseq": "Apd1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR151W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10628851;11909958;14562095;14562106;17322287;22814378;24374639;33491328;7813418", "class_list": "", "function": "Required for normal localization of actin patches. Involved in tolerance to sodium ions and hydrogen peroxide., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQE6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P38281-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38288-1", "uniprot_id": [ { "id": "TOS1_YEAST", "url": "https://www.uniprot.org/uniprot/P38288", "type": "external" } ], "mass": 47994.0, "length": 455, "protein_name": "Probable circularly permuted 1,3-beta-glucanase TOS1", "gene_name": "TOS1", "organism": "Yeast", "refseq_name": "Tos1p", "refseq_ac": [ { "id": "NP_009720", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009720", "type": "external" } ], "gene_names_uniprotkb": "TOS1; YBR1213", "gene_names_refseq": "TOS1", "protein_names_uniprotkb": "Probable circularly permuted 1,3-beta-glucanase TOS1; 3.2.1.39; Target of SBF protein 1", "protein_names_refseq": "Tos1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR162C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "11206552;11935221;14562106;15781460;17563356;20016268;24374639;7597849;7813418", "class_list": "", "function": "Probable circularly permuted 1,3-beta-glucanase involved in cell wall modification through beta-1,3-glucan network alterations such as increased branching or remodeling., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VQF7", "ec_number_list": [], "go_molecular_function": "GO:0042973 glucan endo-1,3-beta-D-glucosidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole;GO:0009277 fungal-type cell wall", "go_biological_process": "GO:0071555 cell wall organization", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P38288-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38305-1", "uniprot_id": [ { "id": "AIM4_YEAST", "url": "https://www.uniprot.org/uniprot/P38305", "type": "external" } ], "mass": 14234.0, "length": 123, "protein_name": "Altered inheritance of mitochondria protein 4", "gene_name": "AIM4", "organism": "Yeast", "refseq_name": "Aim4p", "refseq_ac": [ { "id": "NP_009753", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009753", "type": "external" } ], "gene_names_uniprotkb": "AIM4; SOY1; YBR1404", "gene_names_refseq": "AIM4; SOY1", "protein_names_uniprotkb": "Altered inheritance of mitochondria protein 4; Synthetic with old yellow enzyme protein 1", "protein_names_refseq": "Aim4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR194W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10684247;16989656;17322287;19300474;20210661;22814378;24374639;7813418;8346681", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQI8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P38305-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38314-1", "uniprot_id": [ { "id": "SDS24_YEAST", "url": "https://www.uniprot.org/uniprot/P38314", "type": "external" } ], "mass": 57187.0, "length": 527, "protein_name": "Protein SDS24", "gene_name": "SDS24", "organism": "Yeast", "refseq_name": "Sds24p", "refseq_ac": [ { "id": "NP_009773", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009773", "type": "external" } ], "gene_names_uniprotkb": "SDS24; YBR1501", "gene_names_refseq": "SDS24", "protein_names_uniprotkb": "Protein SDS24", "protein_names_refseq": "Sds24p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR214W)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "14562095;14562106;16041152;17287358;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;21177495;23749301;24374639;30516470;33229814;33481703;33491328;7813418", "class_list": "", "function": "Involved in DNA replication and cell separation during budding., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 5, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 5, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 5, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 25, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VQL0", "ec_number_list": [], "go_molecular_function": "GO:0004865 protein serine/threonine phosphatase inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0000920 septum digestion after cytokinesis;GO:0006897 endocytosis;GO:0042149 cellular response to glucose starvation;GO:0030071 regulation of mitotic metaphase/anaphase transition", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "P38314-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38325-1", "uniprot_id": [ { "id": "OM14_YEAST", "url": "https://www.uniprot.org/uniprot/P38325", "type": "external" } ], "mass": 14610.0, "length": 134, "protein_name": "Mitochondrial outer membrane protein OM14", "gene_name": "OM14", "organism": "Yeast", "refseq_name": "Om14p", "refseq_ac": [ { "id": "NP_009789", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009789", "type": "external" } ], "gene_names_uniprotkb": "OM14; YBR1527", "gene_names_refseq": "OM14", "protein_names_uniprotkb": "Mitochondrial outer membrane protein OM14; Outer membrane protein of 14 kDa", "protein_names_refseq": "Om14p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR230C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;14576278;16689936;17287358;19684113;24374639;33491328;7813418", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, 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"RMD9L_YEAST", "url": "https://www.uniprot.org/uniprot/P38330", "type": "external" } ], "mass": 83761.0, "length": 731, "protein_name": "RNA-binding protein RMD9-like, mitochondrial", "gene_name": "YBR1608", "organism": "Yeast", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_009797", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009797", "type": "external" } ], "gene_names_uniprotkb": "YBR1608", "gene_names_refseq": "", "protein_names_uniprotkb": "RNA-binding protein RMD9-like, mitochondrial", "protein_names_refseq": "uncharacterized protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR238C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562106;19779198;21177495;23749301;24374639;32597660;33481703;33491328;7813418", "class_list": "", "function": "May be involved in the processing or stability of mitochondrial mRNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, 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"YHI0_YEAST", "url": "https://www.uniprot.org/uniprot/P38708", "type": "external" } ], "mass": 77386.0, "length": 688, "protein_name": "Putative proline--tRNA ligase YHR020W", "gene_name": "", "organism": "Yeast", "refseq_name": "proline--tRNA ligase", "refseq_ac": [ { "id": "NP_011884", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011884", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Putative proline--tRNA ligase YHR020W; 6.1.1.15; ProRS; Prolyl-tRNA synthetase", "protein_names_refseq": "proline--tRNA ligase", "tax_id": 559292, "disease": "hypomyelinating leukodystrophy 15 (Disease Ontology:DOID:0070398)", "pathway": " (sce:YHR020W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "18407956;19779198;24374639;27821475;33481703;33491328;8091229", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, 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0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D3DKU0", "ec_number_list": [], "go_molecular_function": "GO:0008320 protein transmembrane transporter activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", 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"missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKP8", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P38746-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38750-1", "uniprot_id": [ { "id": "YHA8_YEAST", "url": "https://www.uniprot.org/uniprot/P38750", "type": "external" } ], "mass": 69969.0, "length": 627, "protein_name": "Uncharacterized transporter YHL008C", "gene_name": "", "organism": "Yeast", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_011855", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011855", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized transporter YHL008C", "protein_names_refseq": "uncharacterized protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YHL008C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "16847258;17322287;18407956;19779198;21126336;23749301;24374639;30516470;32597660;33481703;33491328;8091229", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, 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transport;GO:0015707 nitrite transport", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P38750-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38751-1", "uniprot_id": [ { "id": "SHU1_YEAST", "url": "https://www.uniprot.org/uniprot/P38751", "type": "external" } ], "mass": 17121.0, "length": 150, "protein_name": "Suppressor of HU sensitivity involved in recombination protein 1", "gene_name": "SHU1", "organism": "Yeast", "refseq_name": "Shu1p", "refseq_ac": [ { "id": "NP_011857", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011857", "type": "external" } ], "gene_names_uniprotkb": "SHU1", "gene_names_refseq": "SHU1", "protein_names_uniprotkb": "Suppressor of HU sensitivity involved in recombination protein 1", "protein_names_refseq": "Shu1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHL006C)", "pathway_count": 1, "publication_count": 4, 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true }, { "uniprot_canonical_ac": "P38754-1", "uniprot_id": [ { "id": "RL14B_YEAST", "url": "https://www.uniprot.org/uniprot/P38754", "type": "external" } ], "mass": 15153.0, "length": 138, "protein_name": "Large ribosomal subunit protein eL14B", "gene_name": "RPL14B", "organism": "Yeast", "refseq_name": "60S ribosomal protein eL14 RPL14B", "refseq_ac": [ { "id": "NP_011862", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011862", "type": "external" } ], "gene_names_uniprotkb": "RPL14B", "gene_names_refseq": "RPL14B", "protein_names_uniprotkb": "Large ribosomal subunit protein eL14B; 60S ribosomal protein L14-B", "protein_names_refseq": "60S ribosomal protein eL14 RPL14B", "tax_id": 559292, "disease": "congenital heart disease (Disease Ontology:DOID:1682); systemic lupus erythematosus (Disease Ontology:DOID:9074)", "pathway": " (sce:YHL001W); (R-SCE-156827); (R-SCE-1799339); (R-SCE-72689); (R-SCE-72706); (R-SCE-975956); (R-SCE-975957); (R-SCE-9954709); (R-SCE-9954714)", 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The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKR3", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005730 nucleolus;GO:0005829 cytosol;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0042273 ribosomal large subunit biogenesis;GO:0002181 cytoplasmic translation;GO:0000027 ribosomal large subunit assembly;GO:0000470 maturation of LSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P38754-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38756-1", "uniprot_id": [ { "id": "TCD1_YEAST", "url": "https://www.uniprot.org/uniprot/P38756", "type": "external" } ], "mass": 48883.0, "length": 429, "protein_name": "tRNA threonylcarbamoyladenosine dehydratase 1", "gene_name": "TCD1", "organism": "Yeast", "refseq_name": "tRNA threonylcarbamoyladenosine dehydratase", "refseq_ac": [ { "id": "NP_011866", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011866", "type": "external" } ], "gene_names_uniprotkb": "TCD1", "gene_names_refseq": "TCD1", "protein_names_uniprotkb": "tRNA threonylcarbamoyladenosine dehydratase 1; 6.1.-.-; t(6)A37 dehydratase 1", "protein_names_refseq": "tRNA threonylcarbamoyladenosine dehydratase", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR003C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562106;14576278;16407407;17330950;23242255;24374639;32597660;33491328;8091229", "class_list": "", "function": "Catalyzes the ATP-dependent dehydration of threonylcarbamoyladenosine at position 37 (t(6)A37) to form cyclic t(6)A37 (ct(6)A37) in tRNAs that read codons beginning with adenine., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKU6", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008641 ubiquitin-like modifier activating enzyme activity;GO:0061503 tRNA threonylcarbamoyladenosine dehydratase", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0061504 cyclic threonylcarbamoyladenosine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P38756-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38760-1", "uniprot_id": [ { "id": "MIP6_YEAST", "url": "https://www.uniprot.org/uniprot/P38760", "type": "external" } ], "mass": 75920.0, "length": 659, "protein_name": "RNA-binding protein MIP6", "gene_name": "MIP6", "organism": "Yeast", "refseq_name": "Mip6p", "refseq_ac": [ { "id": "NP_011879", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011879", "type": "external" } ], "gene_names_uniprotkb": "MIP6", "gene_names_refseq": "MIP6", "protein_names_uniprotkb": "RNA-binding protein MIP6; MEX67-interacting protein 6", "protein_names_refseq": "Mip6p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR015W); (R-SCE-156827); (R-SCE-429947); (R-SCE-72649); (R-SCE-975956); (R-SCE-975957)", "pathway_count": 6, "publication_count": 6, "publication_id_list": "14562095;14562106;24374639;33481703;8091229;9214641", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKW0", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003730 mRNA 3'-UTR binding;GO:0008143 poly(A) binding;GO:0008266 poly(U) RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0010494 cytoplasmic stress granule;GO:1990904 ribonucleoprotein complex;GO:0005628 prospore membrane", "go_biological_process": "GO:0016071 mRNA metabolic process;GO:0010609 mRNA localization resulting in post-transcriptional regulation of gene expression;GO:0006417 regulation of translation;GO:0043934 sporulation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P38760-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38765-1", "uniprot_id": [ { "id": "YHI9_YEAST", "url": "https://www.uniprot.org/uniprot/P38765", "type": "external" } ], "mass": 32563.0, "length": 294, "protein_name": "Uncharacterized isomerase YHI9", "gene_name": "YHI9", "organism": "Yeast", "refseq_name": "Yhi9p", "refseq_ac": [ { "id": "NP_011894", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011894", "type": "external" } ], "gene_names_uniprotkb": "YHI9", "gene_names_refseq": "YHI9", "protein_names_uniprotkb": "Uncharacterized isomerase YHI9; 5.1.-.-", "protein_names_refseq": "Yhi9p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR029C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "16021630;16582425;17322287;24374639;8091229", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKX6", "ec_number_list": [], "go_molecular_function": "GO:0016853 isomerase activity", "go_cellular_component": "GO:0000785 chromatin", "go_biological_process": "GO:0030968 endoplasmic reticulum unfolded protein response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P38765-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38767-1", "uniprot_id": [ { "id": "ERC1_YEAST", "url": "https://www.uniprot.org/uniprot/P38767", "type": "external" } ], "mass": 64209.0, "length": 581, "protein_name": "Ethionine resistance-conferring protein 1", "gene_name": "ERC1", "organism": "Yeast", "refseq_name": "Erc1p", "refseq_ac": [ { "id": "NP_011897", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011897", "type": "external" } ], "gene_names_uniprotkb": "ERC1", "gene_names_refseq": "ERC1", "protein_names_uniprotkb": "Ethionine resistance-conferring protein 1", "protein_names_refseq": "Erc1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR032W); (R-SCE-549127)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "16847258;18592490;24374639;33481703;33491328;7765914;8091229", "class_list": "", "function": "Probable transporter involved in ethionine resistance. Overproduction leads to accumulation of S-adenosylmethionine., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKX9", "ec_number_list": [], "go_molecular_function": "GO:0042910 xenobiotic transmembrane transporter activity;GO:0022857 transmembrane transporter activity;GO:0015297 antiporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006556 S-adenosylmethionine biosynthetic process;GO:1990961 xenobiotic detoxification by transmembrane export across the plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P38767-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38769-1", "uniprot_id": [ { "id": "NEL1_YEAST", "url": "https://www.uniprot.org/uniprot/P38769", "type": "external" } ], "mass": 72307.0, "length": 630, "protein_name": "GTPase-activating protein NEL1", "gene_name": "NEL1", "organism": "Yeast", "refseq_name": "GTPase-activating protein NEL1", "refseq_ac": [ { "id": "NP_011900", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011900", "type": "external" } ], "gene_names_uniprotkb": "NEL1", "gene_names_refseq": "NEL1", "protein_names_uniprotkb": "GTPase-activating protein NEL1; Non-ERES-localized SEC23 homolog 1", "protein_names_refseq": "GTPase-activating protein NEL1", "tax_id": 559292, "disease": "craniolenticulosutural dysplasia (Disease Ontology:DOID:0070307)", "pathway": " (sce:YHR035W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;18407956;24374639;24947508;8091229", "class_list": "", "function": "Acts as a GTPase-activating protein (GAP) for SAR1 (PubMed:24947508). Contrary to its SEC23 homolog, NEL1 does not associate with SEC24 and its homologs, nor does it associate with the COPII components, suggesting that it is unlikely that NEL1 functions as a structural component of the vesicle coat machinery (PubMed:24947508). May function as a signaling molecule (PubMed:24947508)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKY2", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0070971 endoplasmic reticulum exit site;GO:0030127 COPII vesicle coat", "go_biological_process": "GO:0090110 COPII-coated vesicle cargo loading;GO:0006886 intracellular protein transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P38769-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38771-1", "uniprot_id": [ { "id": "RRF1_YEAST", "url": "https://www.uniprot.org/uniprot/P38771", "type": "external" } ], "mass": 26407.0, "length": 230, "protein_name": "Ribosome-recycling factor, mitochondrial", "gene_name": "RRF1", "organism": "Yeast", "refseq_name": "Rrf1p", "refseq_ac": [ { "id": "NP_011903", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011903", "type": "external" } ], "gene_names_uniprotkb": "RRF1; FIL1; KIM4", "gene_names_refseq": "FIL1; KIM4; RRF1", "protein_names_uniprotkb": "Ribosome-recycling factor, mitochondrial; RRF; Ribosome-releasing factor, mitochondrial", "protein_names_refseq": "Rrf1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR038W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12853640;14562106;24374639;30516470;33229814;33481703;8091229;8563640;9746366", "class_list": "", "function": "Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D3DKY5", "ec_number_list": [], "go_molecular_function": "GO:0003747 translation release factor activity;GO:0043023 ribosomal large subunit binding", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006412 translation;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P38771-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38772-1", "uniprot_id": [ { "id": "BCD1_YEAST", "url": "https://www.uniprot.org/uniprot/P38772", "type": "external" } ], "mass": 42334.0, "length": 366, "protein_name": "Box C/D snoRNA protein 1", "gene_name": "BCD1", "organism": "Yeast", "refseq_name": "Bcd1p", "refseq_ac": [ { "id": "NP_011906", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011906", "type": "external" } ], "gene_names_uniprotkb": "BCD1", "gene_names_refseq": "BCD1", "protein_names_uniprotkb": "Box C/D snoRNA protein 1", "protein_names_refseq": "Bcd1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR040W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "12837249;14562095;14562106;14690591;17330950;18407956;20190278;21177495;23749301;24374639;33481703;33491328;8091229", "class_list": "", "function": "Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKY8", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0030515 snoRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0070761 pre-snoRNP complex", "go_biological_process": "GO:0016074 sno(s)RNA metabolic process;GO:0042254 ribosome biogenesis;GO:0000492 box C/D snoRNP assembly;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P38772-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38773-1", "uniprot_id": [ { "id": "DOG2_YEAST", "url": "https://www.uniprot.org/uniprot/P38773", "type": "external" } ], "mass": 27165.0, "length": 246, "protein_name": "2-deoxyglucose-6-phosphate phosphatase 2", "gene_name": "DOG2", "organism": "Yeast", "refseq_name": "2-deoxyglucose-6-phosphatase", "refseq_ac": [ { "id": "NP_011909", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011909", "type": "external" } ], "gene_names_uniprotkb": "DOG2", "gene_names_refseq": "DOG2", "protein_names_uniprotkb": "2-deoxyglucose-6-phosphate phosphatase 2; 2-DOG-6-P 2; 2-deoxyglucose-6-phosphatase 2; 3.1.3.68", "protein_names_refseq": "2-deoxyglucose-6-phosphatase", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YHR043C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "14562106;24374639;8091229;8553694", "class_list": "", "function": "Phosphatase that is active on 2-deoxy-D-glucose 6-phosphate (2-DOG-6P), but not very active on fructose-1-P., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKZ1", "ec_number_list": [ { "id": "3.1.3.68", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.68", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003850 2-deoxyglucose-6-phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0006006 glucose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P38773-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38774-1", "uniprot_id": [ { "id": "DOG1_YEAST", "url": "https://www.uniprot.org/uniprot/P38774", "type": "external" } ], "mass": 27100.0, "length": 246, "protein_name": "2-deoxyglucose-6-phosphate phosphatase 1", "gene_name": "DOG1", "organism": "Yeast", "refseq_name": "2-deoxyglucose-6-phosphatase", "refseq_ac": [ { "id": "NP_011910", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011910", "type": "external" } ], "gene_names_uniprotkb": "DOG1", "gene_names_refseq": "DOG1", "protein_names_uniprotkb": "2-deoxyglucose-6-phosphate phosphatase 1; 2-DOG-6-P 1; 2-deoxyglucose-6-phosphatase 1; 3.1.3.68", "protein_names_refseq": "2-deoxyglucose-6-phosphatase", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR044C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;17322287;24374639;7754708;8091229;8553694", "class_list": "", "function": "Phosphatase that is active on 2-deoxy-D-glucose 6-phosphate (2-DOG-6P), as well as on fructose-1-P., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKZ2;P38923", "ec_number_list": [ { "id": "3.1.3.68", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.68", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003850 2-deoxyglucose-6-phosphatase activity", "go_cellular_component": "", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0006006 glucose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P38774-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38776-1", "uniprot_id": [ { "id": "YHK8_YEAST", "url": "https://www.uniprot.org/uniprot/P38776", "type": "external" } ], "mass": 57838.0, "length": 514, "protein_name": "Probable drug/proton antiporter YHK8", "gene_name": "YHK8", "organism": "Yeast", "refseq_name": "Yhk8p", "refseq_ac": [ { "id": "NP_011914", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011914", "type": "external" } ], "gene_names_uniprotkb": "YHK8", "gene_names_refseq": "YHK8", "protein_names_uniprotkb": "Probable drug/proton antiporter YHK8", "protein_names_refseq": "Yhk8p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR048W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12697649;16630275;16847258;24374639;33481703;8091229", "class_list": "", "function": "Probable drug/proton antiporter., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKZ6", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015297 antiporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0055085 transmembrane transport;GO:1902600 proton transmembrane transport;GO:1990961 xenobiotic detoxification by transmembrane export across the plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P38776-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38783-1", "uniprot_id": [ { "id": "FYV4_YEAST", "url": "https://www.uniprot.org/uniprot/P38783", "type": "external" } ], "mass": 15292.0, "length": 130, "protein_name": "Small ribosomal subunit protein mS41", "gene_name": "FYV4", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein mS41 FYV4", "refseq_ac": [ { "id": "NP_011926", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011926", "type": "external" } ], "gene_names_uniprotkb": "FYV4", "gene_names_refseq": "FYV4; mS41", "protein_names_uniprotkb": "Small ribosomal subunit protein mS41; Function required for yeast viability protein 4; Protein FYV4, mitochondrial", "protein_names_refseq": "mitochondrial 37S ribosomal protein mS41 FYV4", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR059W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12663529;14562095;14562106;16552446;17322287;24374639;25609543;28154081;8091229", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane (PubMed:25609543, PubMed:28154081). mS41 is involved in telomere length regulation and required for survival upon exposure to K1 killer toxin (PubMed:12663529, PubMed:16552446)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DL08", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P38783-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38784-1", "uniprot_id": [ { "id": "VMA22_YEAST", "url": "https://www.uniprot.org/uniprot/P38784", "type": "external" } ], "mass": 21078.0, "length": 181, "protein_name": "Vacuolar ATPase assembly protein VMA22", "gene_name": "VMA22", "organism": "Yeast", "refseq_name": "Vma22p", "refseq_ac": [ { "id": "NP_011927", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011927", "type": "external" } ], "gene_names_uniprotkb": "VMA22", "gene_names_refseq": "CEV1; VMA22; VPH6", "protein_names_uniprotkb": "Vacuolar ATPase assembly protein VMA22", "protein_names_refseq": "Vma22p", "tax_id": 559292, "disease": "congenital disorder of glycosylation type IIo (Disease Ontology:DOID:0070267)", "pathway": " (sce:YHR060W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;22814378;24374639;33481703;7673216;8091229", "class_list": "", "function": "Required for V-ATPase activity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DL09", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:1990871 Vma12-Vma22 assembly complex", "go_biological_process": "GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly;GO:0007035 vacuolar acidification", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P38784-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38787-1", "uniprot_id": [ { "id": "PANE_YEAST", "url": "https://www.uniprot.org/uniprot/P38787", "type": "external" } ], "mass": 42821.0, "length": 379, "protein_name": "2-dehydropantoate 2-reductase", "gene_name": "PAN5", "organism": "Yeast", "refseq_name": "2-dehydropantoate 2-reductase PAN5", "refseq_ac": [ { "id": "NP_011930", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011930", "type": "external" } ], "gene_names_uniprotkb": "PAN5", "gene_names_refseq": "PAN5", "protein_names_uniprotkb": "2-dehydropantoate 2-reductase; 1.1.1.169; KPA reductase; KPR; Ketopantoate reductase", "protein_names_refseq": "2-dehydropantoate 2-reductase PAN5", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR063C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "14562106;24374639;33491328;8091229", "class_list": "", "function": "Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DL12", "ec_number_list": [ { "id": "1.1.1.169", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.169", "type": "external" } ], "go_molecular_function": "GO:0050661 NADP binding;GO:0008677 2-dehydropantoate 2-reductase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0015940 pantothenate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P38787-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38795-1", "uniprot_id": [ { "id": "NADE_YEAST", "url": "https://www.uniprot.org/uniprot/P38795", "type": "external" } ], "mass": 80686.0, "length": 714, "protein_name": "Glutamine-dependent NAD(+) synthetase", "gene_name": "QNS1", "organism": "Yeast", "refseq_name": "glutamine-dependent NAD(+) synthetase", "refseq_ac": [ { "id": "NP_011941", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011941", "type": "external" } ], "gene_names_uniprotkb": "QNS1", "gene_names_refseq": "QNS1", "protein_names_uniprotkb": "Glutamine-dependent NAD(+) synthetase; 6.3.5.1; NAD(+) synthase [glutamine-hydrolyzing]", "protein_names_refseq": "glutamine-dependent NAD(+) synthetase", "tax_id": 559292, "disease": "high grade glioma (Disease Ontology:DOID:3070)", "pathway": " (sce:YHR074W); (R-SCE-196807)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "14562106;19779198;24374639;33481703;33491328;8091229", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DL24", "ec_number_list": [ { "id": "6.3.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.5.1", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity;GO:0004359 glutaminase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0009435 NAD+ biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P38795-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38804-1", "uniprot_id": [ { "id": "SDO1L_YEAST", "url": "https://www.uniprot.org/uniprot/P38804", "type": "external" } ], "mass": 12009.0, "length": 111, "protein_name": "Restriction of telomere capping protein 3", "gene_name": "RTC3", "organism": "Yeast", "refseq_name": "Rtc3p", "refseq_ac": [ { "id": "NP_011955", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011955", "type": "external" } ], "gene_names_uniprotkb": "RTC3", "gene_names_refseq": "HGI1; RTC3", "protein_names_uniprotkb": "Restriction of telomere capping protein 3", "protein_names_refseq": "Rtc3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR087W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;14562106;15701634;17322287;18407956;18845848;21177495;24374639;33491328;8091229", "class_list": "", "function": "May play a role in RNA metabolism, rRNA-processing, and in a process influencing telomere capping., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DL39", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P38804-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38809-1", "uniprot_id": [ { "id": "YHP7_YEAST", "url": "https://www.uniprot.org/uniprot/P38809", "type": "external" } ], "mass": 40663.0, "length": 366, "protein_name": "Uncharacterized protein YHR097C", "gene_name": "", "organism": "Yeast", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein YHR097C", "protein_names_refseq": "", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR097C)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "11875433;12872131;14562095;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;21126336;21177495;22218487;23749301;24374639;32597660;33229814;33481703;33491328;33502312;34035143;8091229", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 5, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 5, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 5, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 33, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D3DL47", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0034399 nuclear periphery;GO:0030479 actin cortical patch", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 3.0, "record_id": "P38809-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38812-1", "uniprot_id": [ { "id": "GEP4_YEAST", "url": "https://www.uniprot.org/uniprot/P38812", "type": "external" } ], "mass": 20945.0, "length": 185, "protein_name": "Phosphatidylglycerophosphatase GEP4, mitochondrial", "gene_name": "GEP4", "organism": "Yeast", "refseq_name": "phosphatidylglycerophosphatase", "refseq_ac": [ { "id": "NP_011968", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011968", "type": "external" } ], "gene_names_uniprotkb": "GEP4", "gene_names_refseq": "GEP4", "protein_names_uniprotkb": "Phosphatidylglycerophosphatase GEP4, mitochondrial; 3.1.3.27; Genetic interactor of prohibitins 4; PGP phosphatase GEP4", "protein_names_refseq": "phosphatidylglycerophosphatase", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR100C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "16823961;17322287;19221197;20485265;22814378;24374639;33481703;8091229", "class_list": "", "function": "Phosphatidylglycerophosphatase involved in the biosynthesis of cardiolipin (CL), a unique dimeric phosphoglycerolipid predominantly present in mitochondrial membranes and which has important functions for cellular energy metabolism, mitochondrial dynamics and the initiation of apoptotic pathways. Required for the stability of respiratory chain supercomplexes and for growth at elevated temperature, in presence of ethidium bromide or in absence of prohibitins., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DL50", "ec_number_list": [ { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "GO:0008962 phosphatidylglycerophosphatase activity", "go_cellular_component": "GO:0031314 extrinsic component of mitochondrial inner membrane;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0032049 cardiolipin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P38812-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38813-1", "uniprot_id": [ { "id": "BIG1_YEAST", "url": "https://www.uniprot.org/uniprot/P38813", "type": "external" } ], "mass": 39069.0, "length": 335, "protein_name": "Protein BIG1", "gene_name": "BIG1", "organism": "Yeast", "refseq_name": "Big1p", "refseq_ac": [ { "id": "NP_011969", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011969", "type": "external" } ], "gene_names_uniprotkb": "BIG1", "gene_names_refseq": "BIG1", "protein_names_uniprotkb": "Protein BIG1; Bad in glucose protein 1", "protein_names_refseq": "Big1p", "tax_id": 559292, "disease": "follicular lymphoma (Disease Ontology:DOID:0050873)", "pathway": " (sce:YHR101C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12112232;14562095;14562106;23749301;24374639;32597660;33481703;33491328;8091229;9545237", "class_list": "", "function": "Required for normal beta-1,6-glucan synthesis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, 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"binding_glycan_count": 0, "secondary_ac_list": "D3DL51", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly;GO:0006078 (1->6)-beta-D-glucan biosynthetic process;GO:0071555 cell wall organization", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P38813-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38814-1", "uniprot_id": [ { "id": "SBE22_YEAST", "url": "https://www.uniprot.org/uniprot/P38814", "type": "external" } ], "mass": 96398.0, "length": 852, "protein_name": "Protein SBE22", "gene_name": "SBE22", "organism": "Yeast", "refseq_name": "Sbe22p", "refseq_ac": [ { "id": "NP_011971", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011971", "type": "external" } ], "gene_names_uniprotkb": "SBE22", "gene_names_refseq": "SBE22", "protein_names_uniprotkb": "Protein SBE22", "protein_names_refseq": "Sbe22p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR103W)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "10679005;12045225;12121919;14562095;15665377;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;23749301;24374639;30516470;32597660;33481703;33491328;8091229", "class_list": "", "function": "With SBE2, is involved in cell wall integrity and polarity processes like bud growth, through the transport of CHS3 and UTR2 to sites of growth., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 32, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DL53", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0015031 protein transport;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P38814-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38818-1", "uniprot_id": [ { "id": "CTM1_YEAST", "url": "https://www.uniprot.org/uniprot/P38818", "type": "external" } ], "mass": 68284.0, "length": 585, "protein_name": "Cytochrome c lysine N-methyltransferase 1", "gene_name": "CTM1", "organism": "Yeast", "refseq_name": "cytochrome c lysine N-methyltransferase", "refseq_ac": [ { "id": "NP_011977", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011977", "type": "external" } ], "gene_names_uniprotkb": "CTM1", "gene_names_refseq": "CTM1", "protein_names_uniprotkb": "Cytochrome c lysine N-methyltransferase 1; 2.1.1.59", "protein_names_refseq": "cytochrome c lysine N-methyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR109W)", 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0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DL59;Q66R84", "ec_number_list": [ { "id": "2.1.1.59", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.59", "type": "external" } ], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0042800 histone H3K4 methyltransferase activity;GO:0046975 histone H3K36 methyltransferase activity;GO:0000277 [cytochrome c]-lysine N-methyltransferase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0018022 peptidyl-lysine methylation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P38818-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38824-1", "uniprot_id": [ { "id": "COX23_YEAST", "url": "https://www.uniprot.org/uniprot/P38824", "type": "external" } ], "mass": 17318.0, "length": 151, "protein_name": "Cytochrome c oxidase-assembly factor COX23, mitochondrial", "gene_name": "COX23", "organism": "Yeast", "refseq_name": "Cox23p", "refseq_ac": [ { "id": "NP_011984", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011984", "type": "external" } ], "gene_names_uniprotkb": "COX23", "gene_names_refseq": "COX23", "protein_names_uniprotkb": "Cytochrome c oxidase-assembly factor COX23, mitochondrial", "protein_names_refseq": "Cox23p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR116W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;15145942;17095012;17322287;22984289;24374639;8091229", "class_list": "", 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"reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D3DL66", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0033108 mitochondrial respiratory chain complex assembly;GO:0033617 mitochondrial respiratory chain complex IV assembly", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P38824-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38836-1", "uniprot_id": [ { "id": "ECM14_YEAST", "url": "https://www.uniprot.org/uniprot/P38836", "type": "external" } ], "mass": 49829.0, "length": 430, "protein_name": "Inactive metallocarboxypeptidase ECM14", "gene_name": "ECM14", "organism": 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0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D3DL80", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0006508 proteolysis;GO:0071555 cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P38836-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38837-1", "uniprot_id": [ { "id": "NSG1_YEAST", "url": "https://www.uniprot.org/uniprot/P38837", "type": "external" } ], "mass": 32214.0, "length": 291, "protein_name": "Protein NSG1", "gene_name": "NSG1", "organism": "Yeast", "refseq_name": "Nsg1p", "refseq_ac": [ { "id": "NP_012001", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012001", "type": "external" } ], "gene_names_uniprotkb": "NSG1", "gene_names_refseq": "NSG1", "protein_names_uniprotkb": "Protein NSG1; INSIG homolog 1", "protein_names_refseq": "Nsg1p", "tax_id": 559292, "disease": "end stage renal disease (Disease Ontology:DOID:783); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (sce:YHR133C)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "14562106;15665377;16270032;16847258;17322287;18407956;19779198;19795423;19823750;22218487;24374639;33481703;33491328;8091229", "class_list": "", "function": "Stabilizes the HMG-CoA reductase HMG2 by preventing its HRD1-dependent degradation. Binds directly to the sterol-sensing domain (SSD)-containing transmembrane region of HMG2, promoting its folding to protect it from degradation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DL82;Q6Q5G1", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0071561 nucleus-vacuole junction;GO:0005634 nucleus;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0016126 sterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P38837-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38839-1", "uniprot_id": [ { "id": "SPL2_YEAST", "url": "https://www.uniprot.org/uniprot/P38839", "type": "external" } ], "mass": 17036.0, "length": 148, "protein_name": "Putative cyclin-dependent kinase inhibitor SPL2", "gene_name": "SPL2", "organism": "Yeast", "refseq_name": "Spl2p", "refseq_ac": [ { "id": "NP_012004", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012004", "type": "external" } ], "gene_names_uniprotkb": "SPL2", "gene_names_refseq": "SPL2", "protein_names_uniprotkb": "Putative cyclin-dependent kinase inhibitor SPL2; 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SNU40", "protein_names_uniprotkb": "Protein LIN1", "protein_names_refseq": "U5 snRNP complex subunit LIN1", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR156C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12402242;14562106;17322287;24374639;33481703;33491328;8091229", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLA5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0005682 U5 snRNP", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P38852-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38854-1", "uniprot_id": [ { "id": "TDA11_YEAST", "url": "https://www.uniprot.org/uniprot/P38854", "type": "external" } ], "mass": 56314.0, "length": 504, "protein_name": "Topoisomerase I damage affected protein 11", "gene_name": "TDA11", "organism": "Yeast", "refseq_name": "Tda11p", "refseq_ac": [ { "id": "NP_012029", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012029", "type": "external" } ], "gene_names_uniprotkb": "TDA11", "gene_names_refseq": "TDA11", "protein_names_uniprotkb": "Topoisomerase I damage affected protein 11", "protein_names_refseq": "Tda11p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR159W)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "14562095;14562106;15665377;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21173034;21177495;22218487;22814378;23749301;24374639;30516470;32597660;33481703;33491328;8091229", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 34, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLA8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P38854-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38858-1", "uniprot_id": [ { "id": "SOL3_YEAST", "url": "https://www.uniprot.org/uniprot/P38858", "type": "external" } ], "mass": 27784.0, "length": 249, "protein_name": "6-phosphogluconolactonase 3", "gene_name": "SOL3", "organism": "Yeast", "refseq_name": "6-phosphogluconolactonase SOL3", "refseq_ac": [ { "id": "NP_012033", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012033", "type": "external" } ], "gene_names_uniprotkb": "SOL3", "gene_names_refseq": "SOL3", "protein_names_uniprotkb": "6-phosphogluconolactonase 3; 3.1.1.31; 6PGL", "protein_names_refseq": "6-phosphogluconolactonase SOL3", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR163W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12748633;14562095;14562106;15454531;15905473;22814378;24374639;33491328;8091229;8725220", "class_list": "", "function": "Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLB2", "ec_number_list": [ { "id": "3.1.1.31", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.31", "type": "external" } ], "go_molecular_function": "GO:0017057 6-phosphogluconolactonase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0009051 pentose-phosphate shunt, oxidative branch", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P38858-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38860-1", "uniprot_id": [ { "id": "MTG2_YEAST", "url": "https://www.uniprot.org/uniprot/P38860", "type": "external" } ], "mass": 57847.0, "length": 518, "protein_name": "GTPase MTG2, mitochondrial", "gene_name": "MTG2", "organism": "Yeast", "refseq_name": "putative GTPase MTG2", "refseq_ac": [ { "id": "NP_012038", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012038", "type": "external" } ], "gene_names_uniprotkb": "MTG2", "gene_names_refseq": "MTG2", "protein_names_uniprotkb": "GTPase MTG2, mitochondrial; Mitochondrial GTPase 2", "protein_names_refseq": "putative GTPase MTG2", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR168W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "14562106;15591131;24374639;8091229", "class_list": "", "function": "Required for mitochondrial protein synthesis. May be involved in mitochondrial ribosome biogenesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLB7;Q6DUF2", "ec_number_list": [], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0043022 ribosome binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006412 translation;GO:1902775 mitochondrial large ribosomal subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P38860-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38861-1", "uniprot_id": [ { "id": "NMD3_YEAST", "url": "https://www.uniprot.org/uniprot/P38861", "type": "external" } ], "mass": 59095.0, "length": 518, "protein_name": "60S ribosomal export protein NMD3", "gene_name": "NMD3", "organism": "Yeast", "refseq_name": "ribosome-binding protein NMD3", "refseq_ac": [ { "id": "NP_012040", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012040", "type": "external" } ], "gene_names_uniprotkb": "NMD3", "gene_names_refseq": "NMD3; SRC5", "protein_names_uniprotkb": "60S ribosomal export protein NMD3; Nonsense-mediated mRNA decay protein 3", "protein_names_refseq": "ribosome-binding protein NMD3", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR170W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11086007;14562106;19779198;24374639;32597660;33481703;33491328;8091229", "class_list": "", "function": "Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit. Unlikely to play a significant role in nonsense-mediated mRNA decay (NMD)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLB9", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0043023 ribosomal large subunit binding;GO:0070180 large ribosomal subunit rRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0000055 ribosomal large subunit export from nucleus;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P38861-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38865-1", "uniprot_id": [ { "id": "CTR2_YEAST", "url": "https://www.uniprot.org/uniprot/P38865", "type": "external" } ], "mass": 21651.0, "length": 189, "protein_name": "Copper transport protein CTR2", "gene_name": "CTR2", "organism": "Yeast", "refseq_name": "low-affinity Cu transporter", "refseq_ac": [ { "id": "NP_012045", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012045", "type": "external" } ], "gene_names_uniprotkb": "CTR2", "gene_names_refseq": "CTR2", "protein_names_uniprotkb": "Copper transport protein CTR2; Copper transporter 2", "protein_names_refseq": "low-affinity Cu transporter", "tax_id": 559292, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); Wilson disease (Disease Ontology:DOID:893)", "pathway": " (sce:YHR175W); (R-SCE-425410)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "15494390;16847258;24374639;33491328;7499355;8091229", "class_list": "", "function": "Provides bioavailable copper via mobilization of vacuolar copper stores and export to the cytoplasm., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLC3", "ec_number_list": [], "go_molecular_function": "GO:0005375 copper ion transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0035434 copper ion transmembrane transport;GO:0006878 intracellular copper ion homeostasis;GO:0006825 copper ion transport;GO:0015677 copper ion import", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P38865-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38866-1", "uniprot_id": [ { "id": "FMO1_YEAST", "url": "https://www.uniprot.org/uniprot/P38866", "type": "external" } ], "mass": 49099.0, "length": 432, "protein_name": "Thiol-specific monooxygenase", "gene_name": "FMO1", "organism": "Yeast", "refseq_name": "N,N-dimethylaniline monooxygenase", "refseq_ac": [ { "id": "NP_012046", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012046", "type": "external" } ], "gene_names_uniprotkb": "FMO1", "gene_names_refseq": "FMO1", "protein_names_uniprotkb": "Thiol-specific monooxygenase; 1.14.13.-; Flavin-dependent monooxygenase", "protein_names_refseq": "N,N-dimethylaniline monooxygenase", "tax_id": 559292, "disease": "chromosome 1q21.1 deletion syndrome (Disease Ontology:DOID:0060411); trimethylaminuria (Disease Ontology:DOID:0080361); hypertension (Disease Ontology:DOID:10763); inherited metabolic disorder (Disease Ontology:DOID:655)", "pathway": " (sce:YHR176W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12139977;22814378;24374639;33491328;8091229", "class_list": "", "function": "Flavin-dependent oxidation of thiol-containing compounds. Probably required for the correct folding of disulfide-bonded proteins., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLC5;Q6UZ93", "ec_number_list": [], "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0050661 NADP binding;GO:0004497 monooxygenase activity;GO:0004499 N,N-dimethylaniline monooxygenase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P38866-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38872-1", "uniprot_id": [ { "id": "ADY1_YEAST", "url": "https://www.uniprot.org/uniprot/P38872", "type": "external" } ], "mass": 27884.0, "length": 237, "protein_name": "Prospore formation at selected spindle poles protein 1", "gene_name": "PFS1", "organism": "Yeast", "refseq_name": "Pfs1p", "refseq_ac": [ { "id": "NP_012055", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012055", "type": "external" } ], "gene_names_uniprotkb": "PFS1; ADY1", "gene_names_refseq": "ADY1; PFS1", "protein_names_uniprotkb": "Prospore formation at selected spindle poles protein 1; Accumulates dyads protein 1", "protein_names_refseq": "Pfs1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR185C)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "11553705;24374639;8091229", "class_list": "", "function": "Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation. Required to localize MPC54 to all four spindle pole bodies, and localize DON1 and SPO14 to four prospore membranes., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLD3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005816 spindle pole body", "go_biological_process": "GO:0030476 ascospore wall assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P38872-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38876-1", "uniprot_id": [ { "id": "PTH_YEAST", "url": "https://www.uniprot.org/uniprot/P38876", "type": "external" } ], "mass": 21036.0, "length": 190, "protein_name": "Peptidyl-tRNA hydrolase", "gene_name": "PTH1", "organism": "Yeast", "refseq_name": "aminoacyl-tRNA hydrolase", "refseq_ac": [ { "id": "NP_012059", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012059", "type": "external" } ], "gene_names_uniprotkb": "PTH1", "gene_names_refseq": "PTH1", "protein_names_uniprotkb": "Peptidyl-tRNA hydrolase; 3.1.1.29; PTH", "protein_names_refseq": "aminoacyl-tRNA hydrolase", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR189W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12100553;12475929;12799450;14562095;14562106;24374639;8091229;8563640", "class_list": "", "function": "Peptidyl-tRNA hydrolase involved in the recycling of tRNA-Lys from diacetyl-lysyl-tRNA-Lys and is important for mitochondrial function., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLD7", "ec_number_list": [ { "id": "3.1.1.29", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.29", "type": "external" } ], "go_molecular_function": "GO:0004045 peptidyl-tRNA hydrolase activity;GO:0000049 tRNA binding", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P38876-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38880-1", "uniprot_id": [ { "id": "MDM31_YEAST", "url": "https://www.uniprot.org/uniprot/P38880", "type": "external" } ], "mass": 66703.0, "length": 579, "protein_name": "Mitochondrial distribution and morphology protein 31", "gene_name": "MDM31", "organism": "Yeast", "refseq_name": "Mdm31p", "refseq_ac": [ { "id": "NP_012064", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012064", "type": "external" } ], "gene_names_uniprotkb": "MDM31", "gene_names_refseq": "MDM31", "protein_names_uniprotkb": "Mitochondrial distribution and morphology protein 31", "protein_names_refseq": "Mdm31p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR194W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11907266;14562095;14562106;15631992;16847258;24374639;8091229", "class_list": "", "function": "Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLE2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0007005 mitochondrion organization;GO:0006873 intracellular monoatomic ion homeostasis;GO:1900208 regulation of cardiolipin metabolic process;GO:0000001 mitochondrion inheritance", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P38880-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38884-1", "uniprot_id": [ { "id": "AIM18_YEAST", "url": "https://www.uniprot.org/uniprot/P38884", "type": "external" } ], "mass": 36502.0, "length": 321, "protein_name": "Altered inheritance of mitochondria protein 18, mitochondrial", "gene_name": "AIM18", "organism": "Yeast", "refseq_name": "Aim18p", "refseq_ac": [ { "id": "NP_012068", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012068", "type": "external" } ], "gene_names_uniprotkb": "AIM18; FMP22", "gene_names_refseq": "AIM18; FMP22", "protein_names_uniprotkb": "Altered inheritance of mitochondria protein 18, mitochondrial; Found in mitochondrial proteome protein 22", "protein_names_refseq": "Aim18p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR198C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;14562106;17322287;19300474;24374639;8091229", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, 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"go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P38884-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38885-1", "uniprot_id": [ { "id": "AIM46_YEAST", "url": "https://www.uniprot.org/uniprot/P38885", "type": "external" } ], "mass": 34113.0, "length": 310, "protein_name": "Altered inheritance of mitochondria protein 46, mitochondrial", "gene_name": "AIM46", "organism": "Yeast", "refseq_name": "Aim46p", "refseq_ac": [ { "id": "NP_012069", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012069", "type": "external" } ], "gene_names_uniprotkb": "AIM46; FMP34", "gene_names_refseq": "AIM46; FMP34", "protein_names_uniprotkb": "Altered inheritance of mitochondria protein 46, mitochondrial; Found in mitochondrial proteome protein 34", 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0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLE7", "ec_number_list": [], "go_molecular_function": "GO:0020037 heme binding;GO:0016872 intramolecular lyase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P38885-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38892-1", "uniprot_id": [ { "id": "CRG1_YEAST", "url": "https://www.uniprot.org/uniprot/P38892", "type": "external" } ], "mass": 33785.0, "length": 291, "protein_name": "Probable S-adenosylmethionine-dependent methyltransferase CRG1", "gene_name": "CRG1", "organism": "Yeast", "refseq_name": "S-adenosylmethionine-dependent methyltransferase", "refseq_ac": [ { "id": "NP_012079", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012079", "type": "external" } ], "gene_names_uniprotkb": "CRG1", "gene_names_refseq": "CRG1", "protein_names_uniprotkb": "Probable S-adenosylmethionine-dependent methyltransferase CRG1; 2.1.1.-; Cantharidin resistance protein 1", "protein_names_refseq": "S-adenosylmethionine-dependent methyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR209W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;15116342;17322287;18622389;23749301;24374639;8091229;9873020", "class_list": "", "function": "Probable S-adenosylmethionine-dependent methyltransferase which mediates cantharidin resistance., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLF8;Q6Q5R3", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0008168 methyltransferase activity;GO:0008757 S-adenosylmethionine-dependent methyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0055088 lipid homeostasis;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P38892-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38904-1", "uniprot_id": [ { "id": "SPP41_YEAST", "url": "https://www.uniprot.org/uniprot/P38904", "type": "external" } ], "mass": 161597.0, "length": 1435, "protein_name": "Protein SPP41", "gene_name": "SPP41", "organism": "Yeast", "refseq_name": "Spp41p", "refseq_ac": [ { "id": "NP_010752", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010752", "type": "external" } ], "gene_names_uniprotkb": "SPP41", "gene_names_refseq": "SPP41", "protein_names_uniprotkb": "Protein SPP41", "protein_names_refseq": "Spp41p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR464W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "15166219;17330950;17563356;18407956;19779198;20702584;21177495;22218487;23749301;24374639;32597660;33481703;33491328;33502312;8005438;9169867", "class_list": "", "function": "Negative regulator of PRP3 and PRP4 genes., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 30, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT89;Q03291", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0010629 negative regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P38904-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38909-1", "uniprot_id": [ { "id": "CYC2_YEAST", "url": "https://www.uniprot.org/uniprot/P38909", "type": "external" } ], "mass": 42368.0, "length": 366, "protein_name": "Cytochrome c mitochondrial import factor CYC2", "gene_name": "CYC2", "organism": "Yeast", "refseq_name": "oxidoreductase", "refseq_ac": [ { "id": "NP_014680", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014680", "type": "external" } ], "gene_names_uniprotkb": "CYC2; OR26.30", "gene_names_refseq": "CYC2", "protein_names_uniprotkb": "Cytochrome c mitochondrial import factor CYC2; 1.-.-.-; Cytochrome c assembly flavoprotein CYC2", "protein_names_refseq": "oxidoreductase", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR037W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12748633;14562095;14562106;14576278;16207709;24374639;8413243;9169874", "class_list": "", "function": "Redox component that participates in c-type cytochrome biogenesis in the mitochondrial intermembrane space. May play a role in the reduction of heme prior to its ligation to apocytochrome c by cytochrome c heme lyase. Has oxidoreductase activity in vitro., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2A4", "ec_number_list": [], "go_molecular_function": "GO:0016491 oxidoreductase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0018063 cytochrome c-heme linkage;GO:0007006 mitochondrial membrane organization", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P38909-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38913-1", "uniprot_id": [ { "id": "FAD1_YEAST", "url": "https://www.uniprot.org/uniprot/P38913", "type": "external" } ], "mass": 35546.0, "length": 306, "protein_name": "FAD synthase", "gene_name": "FAD1", "organism": "Yeast", "refseq_name": "FMN adenylyltransferase", "refseq_ac": [ { "id": "NP_010239", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010239", "type": "external" } ], "gene_names_uniprotkb": "FAD1; D2702", "gene_names_refseq": "FAD1", "protein_names_uniprotkb": "FAD synthase; 2.7.7.2; FMN adenylyltransferase; FMNAT; Flavin adenine dinucleotide synthase", "protein_names_refseq": "FMN adenylyltransferase", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YDL045C); (R-SCE-196843)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "17322287;20359485;24374639;33481703;33491328;34575116;7799934;9046088;9169867", "class_list": "", "function": "Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRV1", "ec_number_list": [ { "id": "2.7.7.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.2", "type": "external" } ], "go_molecular_function": "GO:0003919 FMN adenylyltransferase activity;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006747 FAD biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P38913-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38921-1", "uniprot_id": [ { "id": "PET8_YEAST", "url": "https://www.uniprot.org/uniprot/P38921", "type": "external" } ], "mass": 31027.0, "length": 284, "protein_name": "Mitochondrial S-adenosylmethionine carrier protein", "gene_name": "PET8", "organism": "Yeast", "refseq_name": "Pet8p", "refseq_ac": [ { "id": "NP_014395", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014395", "type": "external" } ], "gene_names_uniprotkb": "PET8; N2012; SAM5", "gene_names_refseq": "PET8; SAM5", "protein_names_uniprotkb": "Mitochondrial S-adenosylmethionine carrier protein", "protein_names_refseq": "Pet8p", "tax_id": 559292, "disease": "combined oxidative phosphorylation deficiency 28 (Disease Ontology:DOID:0111470)", "pathway": " (sce:YNL003C); (R-SCE-549127)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "14562106;14609944;24374639;7941739;7985421;8402262;9169873;9178508", "class_list": "", "function": "S-adenosylmethionine (SAM) transporter of the mitochondrial inner membrane. Also transports S-adenosylhomocysteine (SAH). Probably catalyzes the uptake of SAM into the mitochondria, where it is required for the activity of BIO2, LIP5 and for methylation of DNA, RNA, proteins and other compounds, and the export of SAH, which is produced from SAM in the methylation reactions and hydrolyzed in the cytosol by SAH1. The rate of the exchange is much higher than that of the uniport. However, the uniport reaction is necessary in special conditions, when the intramitochondrial level of SAM has to be increased when cells divide or when cells are transferred to a medium containing non-fermentative carbon sources., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1H4", "ec_number_list": [], "go_molecular_function": "GO:0000095 S-adenosyl-L-methionine transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0015805 S-adenosyl-L-methionine transport", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P38921-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38957-1", "uniprot_id": [ { "id": "SHU2_YEAST", "url": "https://www.uniprot.org/uniprot/P38957", "type": "external" } ], "mass": 26123.0, "length": 223, "protein_name": "Suppressor of hydroxyurea sensitivity protein 2", "gene_name": "SHU2", "organism": "Yeast", "refseq_name": "Shu2p", "refseq_ac": [ { "id": "NP_010363", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010363", "type": "external" } ], "gene_names_uniprotkb": "SHU2; D4436", "gene_names_refseq": "SHU2", "protein_names_uniprotkb": "Suppressor of hydroxyurea sensitivity protein 2", "protein_names_refseq": "Shu2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR078C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12972632;15654096;17322287;17671161;19496932;24374639;9169867", "class_list": "", "function": "Plays a role in a RAD51/RAD54-dependent homologous recombination repair (HRR) pathway to repair MMS-induced lesions during S-phase. Required for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS64", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0035861 site of double-strand break;GO:0097196 Shu complex", "go_biological_process": "GO:0000725 recombinational repair;GO:0000730 DNA recombinase assembly;GO:0042275 error-free postreplication DNA repair;GO:0043007 maintenance of rDNA;GO:1903112 positive regulation of single-strand break repair via homologous recombination", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P38957-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38958-1", "uniprot_id": [ { "id": "PT100_YEAST", "url": "https://www.uniprot.org/uniprot/P38958", "type": "external" } ], "mass": 13188.0, "length": 111, "protein_name": "Protein PET100, mitochondrial", "gene_name": "PET100", "organism": "Yeast", "refseq_name": "Pet100p", "refseq_ac": [ { "id": "NP_010364", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010364", "type": "external" } ], "gene_names_uniprotkb": "PET100; D4441", "gene_names_refseq": "PET100", "protein_names_uniprotkb": "Protein PET100, mitochondrial", "protein_names_refseq": "Pet100p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR079W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;17322287;24374639;8702496;9169867", "class_list": "", "function": "Required for the biogenesis of cytochrome c oxidase. Probably for its assembly into an active holoenzyme., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS65", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0033617 mitochondrial respiratory chain complex IV assembly", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P38958-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38962-1", "uniprot_id": [ { "id": "TVP23_YEAST", "url": "https://www.uniprot.org/uniprot/P38962", "type": "external" } ], "mass": 23148.0, "length": 199, "protein_name": "Golgi apparatus membrane protein TVP23", "gene_name": "TVP23", "organism": "Yeast", "refseq_name": "Tvp23p", "refseq_ac": [ { "id": "NP_010369", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010369", "type": "external" } ], "gene_names_uniprotkb": "TVP23; D4466", "gene_names_refseq": "TVP23", "protein_names_uniprotkb": "Golgi apparatus membrane protein TVP23; TLG2 compartment vesicle protein of 23 kDa", "protein_names_refseq": "Tvp23p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR084C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;16107716;17178117;17322287;24374639;9169867", "class_list": "", "function": "Golgi membrane protein involved in vesicular trafficking., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VS71", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005737 cytoplasm", "go_biological_process": "GO:0016192 vesicle-mediated transport;GO:0009306 protein secretion", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P38962-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38966-1", "uniprot_id": [ { "id": "VTC5_YEAST", "url": "https://www.uniprot.org/uniprot/P38966", "type": "external" } ], "mass": 98712.0, "length": 869, "protein_name": "Vacuole transporter chaperone complex subunit 5", "gene_name": "VTC5", "organism": "Yeast", "refseq_name": "Vtc5p", "refseq_ac": [ { "id": "NP_010374", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010374", "type": "external" } ], "gene_names_uniprotkb": "VTC5; D4495; YD8554.22", "gene_names_refseq": "VTC5", "protein_names_uniprotkb": "Vacuole transporter chaperone complex subunit 5; PolyP polymerase; Vacuolar membrane polyphosphate polymerase regulatory subunit 5", "protein_names_refseq": "Vtc5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR089W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "14562106;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21177495;23749301;24374639;27587415;32597660;33481703;33491328;34544285;9169867", "class_list": "", "function": "Regulatory subunit of the vacuolar transporter chaperone (VTC) complex (PubMed:27587415). The VTC complex acts as a vacuolar polyphosphate polymerase that catalyzes the synthesis of inorganic polyphosphate (polyP) via transfer of phosphate from ATP to a growing polyP chain, releasing ADP. VTC exposes its catalytic domain VTC4 to the cytosol, where the growing polyP chain winds through a tunnel-shaped pocket, integrating cytoplasmic polymer synthesis with polyP membrane translocation (Probable). The VTC complex carries 9 vacuolar transmembrane domains, which are likely to constitute the translocation channel into the organelle lumen (Probable). PolyP synthesis is tightly coupled to its transport into the vacuole lumen, in order to avoid otherwise toxic intermediates in the cytosol, and it depends on the proton gradient across the membrane, formed by V-ATPase (Probable). VTC5 interacts with the VTC complex to increase the rate of polyP production (PubMed:27587415)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 26, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS76;Q03192", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0000329 fungal-type vacuole membrane;GO:0033254 vacuolar transporter chaperone complex", "go_biological_process": "GO:0030643 intracellular phosphate ion homeostasis;GO:0006799 polyphosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P38966-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38969-1", "uniprot_id": [ { "id": "PNT1_YEAST", "url": "https://www.uniprot.org/uniprot/P38969", "type": "external" } ], "mass": 48934.0, "length": 423, "protein_name": "Pentamidine resistance factor, mitochondrial", "gene_name": "PNT1", "organism": "Yeast", "refseq_name": "Pnt1p", "refseq_ac": [ { "id": "NP_014909", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014909", "type": "external" } ], "gene_names_uniprotkb": "PNT1", "gene_names_refseq": "PNT1", "protein_names_uniprotkb": "Pentamidine resistance factor, mitochondrial", "protein_names_refseq": "Pnt1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR266W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10490599;11950926;14562106;16823961;17322287;24374639;7634332;7695273;9153759;9169874", "class_list": "", "function": "Probably involved in mitochondrial export. Confers resistance to the anti-pneumocystis carinii drug pentamidine. May act by the removal of pentamidine, or its damage targets, from the matrix by an active-transport mechanism., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2W6;Q08730", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0046677 response to antibiotic;GO:0032979 protein insertion into mitochondrial inner membrane from matrix", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P38969-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38971-1", "uniprot_id": [ { "id": "ALP1_YEAST", "url": "https://www.uniprot.org/uniprot/P38971", "type": "external" } ], "mass": 64014.0, "length": 573, "protein_name": "Basic amino-acid permease", "gene_name": "ALP1", "organism": "Yeast", "refseq_name": "arginine permease ALP1", "refseq_ac": [ { "id": "NP_014129", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014129", "type": "external" } ], "gene_names_uniprotkb": "ALP1; N0660", "gene_names_refseq": "ALP1; APL1", "protein_names_uniprotkb": "Basic amino-acid permease", "protein_names_refseq": "arginine permease ALP1", "tax_id": 559292, "disease": "retinitis pigmentosa 68 (Disease Ontology:DOID:0110374)", "pathway": " (sce:YNL270C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10654085;16847258;24374639;7941748;8740425;9169873", "class_list": "", "function": "High-affinity permease for basic amino acids., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0S4", "ec_number_list": [], "go_molecular_function": "GO:0015171 amino acid transmembrane transporter activity;GO:0015174 basic amino acid transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0015802 basic amino acid transport;GO:0003333 amino acid transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P38971-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38972-1", "uniprot_id": [ { "id": "PUR4_YEAST", "url": "https://www.uniprot.org/uniprot/P38972", "type": "external" } ], "mass": 148905.0, "length": 1358, "protein_name": "Phosphoribosylformylglycinamidine synthase", "gene_name": "ADE6", "organism": "Yeast", "refseq_name": "phosphoribosylformylglycinamidine synthase", "refseq_ac": [ { "id": "NP_011575", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011575", "type": "external" } ], "gene_names_uniprotkb": "ADE6", "gene_names_refseq": "ADE6", "protein_names_uniprotkb": "Phosphoribosylformylglycinamidine synthase; 6.3.5.3; FGAM synthase; FGAMS; FGAR amidotransferase; FGAR-AT; Formylglycinamide ribonucleotide amidotransferase; Formylglycinamide ribotide amidotransferase", "protein_names_refseq": "phosphoribosylformylglycinamidine synthase", "tax_id": 559292, "disease": "colon adenocarcinoma (Disease Ontology:DOID:234); renal cell carcinoma (Disease Ontology:DOID:4450); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (sce:YGR061C); (R-SCE-73817)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "14562106;18407956;22814378;23749301;24374639;33481703;33491328;9169869", "class_list": "", "function": "Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VUJ6", "ec_number_list": [ { "id": "6.3.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.5.3", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004642 phosphoribosylformylglycinamidine synthase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006164 purine nucleotide biosynthetic process;GO:0006189 'de novo' IMP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P38972-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38986-1", "uniprot_id": [ { "id": "ASPG1_YEAST", "url": "https://www.uniprot.org/uniprot/P38986", "type": "external" } ], "mass": 41395.0, "length": 381, "protein_name": "L-asparaginase 1", "gene_name": "ASP1", "organism": "Yeast", "refseq_name": "asparaginase ASP1", "refseq_ac": [ { "id": "NP_010607", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010607", "type": "external" } ], "gene_names_uniprotkb": "ASP1; D9798.6", "gene_names_refseq": "ASP1", "protein_names_uniprotkb": "L-asparaginase 1; 3.5.1.1; ASP I; L-asparaginase I; L-asparagine amidohydrolase I", "protein_names_refseq": "asparaginase ASP1", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR321W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "18407956;19795423;19823750;21126336;24374639;32597660;33481703;33491328;8026756;9169867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSV3", "ec_number_list": [ { "id": "3.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.1", "type": "external" } ], "go_molecular_function": "GO:0004067 asparaginase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0042597 periplasmic space", "go_biological_process": "GO:0006530 L-asparagine catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P38986-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38988-1", "uniprot_id": [ { "id": "GGC1_YEAST", "url": "https://www.uniprot.org/uniprot/P38988", "type": "external" } ], "mass": 33215.0, "length": 300, "protein_name": "Mitochondrial GTP/GDP carrier protein 1", "gene_name": "GGC1", "organism": "Yeast", "refseq_name": "Ggc1p", "refseq_ac": [ { "id": "NP_010083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010083", "type": "external" } ], "gene_names_uniprotkb": "GGC1; D1214; SHM1; YHM1", "gene_names_refseq": "GGC1; SHM1; YHM1", "protein_names_uniprotkb": "Mitochondrial GTP/GDP carrier protein 1", "protein_names_refseq": "Ggc1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL198C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14576278;14629196;14998997;17322287;22814378;24374639;8896272;8905928;9169867", "class_list": "", "function": "Mitochondrial GTP/GDP transporter required for GTP uptake and GDP exit from mitochondria. Involved in mitochondrial iron transport and essential for mitochondrial genome maintenance., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRF6", "ec_number_list": [], "go_molecular_function": "GO:0001409 guanine nucleotide transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0055085 transmembrane transport;GO:0006879 intracellular iron ion homeostasis;GO:0001408 guanine nucleotide transport", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P38988-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P38999-1", "uniprot_id": [ { "id": "LYS9_YEAST", "url": "https://www.uniprot.org/uniprot/P38999", "type": "external" } ], "mass": 48918.0, "length": 446, "protein_name": "Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]", "gene_name": "LYS9", "organism": "Yeast", "refseq_name": "saccharopine dehydrogenase (NADP+, L-glutamate-forming)", "refseq_ac": [ { "id": "NP_014448", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014448", "type": "external" } ], "gene_names_uniprotkb": "LYS9; LYS13; N3461", "gene_names_refseq": "LYS13; LYS9", "protein_names_uniprotkb": "Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]; 1.5.1.10; Saccharopine reductase", "protein_names_refseq": "saccharopine dehydrogenase (NADP+, L-glutamate-forming)", "tax_id": 559292, "disease": "hyperlysinemia (Disease Ontology:DOID:9274)", "pathway": " (sce:YNR050C); (R-SCE-71064)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "14562106;15899842;17322287;21126336;24374639;33481703;33491328;8935650;9169873", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1M5;E9P930", "ec_number_list": [ { "id": "1.5.1.10", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.10", "type": "external" } ], "go_molecular_function": "GO:0004753 saccharopine dehydrogenase activity;GO:0004755 saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0071944 cell periphery", "go_biological_process": "GO:0019878 lysine biosynthetic process via aminoadipic acid", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P38999-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39000-1", "uniprot_id": [ { "id": "SHC1_YEAST", "url": "https://www.uniprot.org/uniprot/P39000", "type": "external" } ], "mass": 56578.0, "length": 512, "protein_name": "Protein SHC1", "gene_name": "SHC1", "organism": "Yeast", "refseq_name": "Shc1p", "refseq_ac": [ { "id": "NP_011022", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011022", "type": "external" } ], "gene_names_uniprotkb": "SHC1", "gene_names_refseq": "SHC1", "protein_names_uniprotkb": "Protein SHC1; Sporulation-specific homolog of CSD4", "protein_names_refseq": "Shc1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER096W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10082665;11918806;15715908;15755916;1581961;24374639;9169868", "class_list": "", "function": "Required for the activation of chitin synthase III (CHS3) activity during the sporulation process., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM04", "ec_number_list": [], "go_molecular_function": "GO:0008047 enzyme activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005628 prospore membrane", "go_biological_process": "GO:0006031 chitin biosynthetic process;GO:0030437 ascospore formation;GO:0071555 cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P39000-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39005-1", "uniprot_id": [ { "id": "KRE9_YEAST", "url": "https://www.uniprot.org/uniprot/P39005", "type": "external" } ], "mass": 29989.0, "length": 276, "protein_name": "Cell wall synthesis protein KRE9", "gene_name": "KRE9", "organism": "Yeast", "refseq_name": "Kre9p", "refseq_ac": [ { "id": "NP_012361", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012361", "type": "external" } ], "gene_names_uniprotkb": "KRE9; J0504", "gene_names_refseq": "KRE9", "protein_names_uniprotkb": "Cell wall synthesis protein KRE9; Killer toxin resistant protein 9", "protein_names_refseq": "Kre9p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL174W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "24374639;29897761;8413233;8462845;8641269", "class_list": "", "function": "Involved in cell wall beta(1->6) glucan synthesis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VW14", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0006077 (1->6)-beta-D-glucan metabolic process;GO:0042546 cell wall biogenesis;GO:0006078 (1->6)-beta-D-glucan biosynthetic process;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P39005-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39076-1", "uniprot_id": [ { "id": "TCPB_YEAST", "url": "https://www.uniprot.org/uniprot/P39076", "type": "external" } ], "mass": 57203.0, "length": 527, "protein_name": "T-complex protein 1 subunit beta", "gene_name": "CCT2", "organism": "Yeast", "refseq_name": "chaperonin-containing T-complex subunit CCT2", "refseq_ac": [ { "id": "NP_012124", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012124", "type": "external" } ], "gene_names_uniprotkb": "CCT2; BIN3; TCP2", "gene_names_refseq": "BIN3; CCT2; TCP2", "protein_names_uniprotkb": "T-complex protein 1 subunit beta; CCT-beta; TCP-1-beta", "protein_names_refseq": "chaperonin-containing T-complex subunit CCT2", "tax_id": 559292, "disease": "Leber congenital amaurosis (Disease Ontology:DOID:14791); candidiasis (Disease Ontology:DOID:1508)", "pathway": " (sce:YIL142W); (R-SCE-390471); (R-SCE-6798695); (R-SCE-6814122)", "pathway_count": 4, "publication_count": 12, "publication_id_list": "17322287;17429077;17563356;18407956;22814378;23749301;24374639;33481703;33491328;7908441;7916460;9169870", "class_list": "", "function": "Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. In yeast may play a role in mitotic spindle formation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVE5", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity;GO:0140662 ATP-dependent protein folding chaperone", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005832 chaperonin-containing T-complex", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P39076-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39077-1", "uniprot_id": [ { "id": "TCPG_YEAST", "url": "https://www.uniprot.org/uniprot/P39077", "type": "external" } ], "mass": 58814.0, "length": 534, "protein_name": "T-complex protein 1 subunit gamma", "gene_name": "CCT3", "organism": "Yeast", "refseq_name": "chaperonin-containing T-complex subunit CCT3", "refseq_ac": [ { "id": "NP_012520", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012520", "type": "external" } ], "gene_names_uniprotkb": "CCT3; BIN2; J1336; TCP3", "gene_names_refseq": "BIN2; CCT3; TCP3", "protein_names_uniprotkb": "T-complex protein 1 subunit gamma; CCT-gamma; TCP-1-gamma", "protein_names_refseq": "chaperonin-containing T-complex subunit CCT3", "tax_id": 559292, "disease": "intrinsic cardiomyopathy (Disease Ontology:DOID:0060036)", "pathway": " (sce:YJL014W); (R-SCE-390471); (R-SCE-6814122)", "pathway_count": 3, "publication_count": 10, "publication_id_list": "17330950;19779198;21126336;22814378;24374639;32597660;33481703;33491328;7916460;8641269", "class_list": "", "function": "Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. In yeast may play a role in mitotic spindle formation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWG3", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity;GO:0140662 ATP-dependent protein folding chaperone", "go_cellular_component": "GO:0005832 chaperonin-containing T-complex", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P39077-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39078-1", "uniprot_id": [ { "id": "TCPD_YEAST", "url": "https://www.uniprot.org/uniprot/P39078", "type": "external" } ], "mass": 57604.0, "length": 528, "protein_name": "T-complex protein 1 subunit delta", "gene_name": "CCT4", "organism": "Yeast", "refseq_name": "chaperonin-containing T-complex subunit CCT4", "refseq_ac": [ { "id": "NP_010138", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010138", "type": "external" } ], "gene_names_uniprotkb": "CCT4; ANC2; TCP4", "gene_names_refseq": "ANC2; CCT4; TCP4", "protein_names_uniprotkb": "T-complex protein 1 subunit delta; CCT-delta; TCP-1-delta", "protein_names_refseq": "chaperonin-containing T-complex subunit CCT4", "tax_id": 559292, "disease": "hereditary sensory and autonomic neuropathy (Disease Ontology:DOID:0050548); intrinsic cardiomyopathy (Disease Ontology:DOID:0060036)", "pathway": " (sce:YDL143W); (R-SCE-390471); (R-SCE-6814122)", "pathway_count": 3, "publication_count": 9, "publication_id_list": "14562106;21126336;22218487;24374639;33229814;33481703;33491328;7916461;9169867", "class_list": "", "function": "Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. In yeast may play a role in mitotic spindle formation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VRK5;Q07561", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity;GO:0140662 ATP-dependent protein folding chaperone", "go_cellular_component": "GO:0005832 chaperonin-containing T-complex", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P39078-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39079-1", "uniprot_id": [ { "id": "TCPZ_YEAST", "url": "https://www.uniprot.org/uniprot/P39079", "type": "external" } ], "mass": 59924.0, "length": 546, "protein_name": "T-complex protein 1 subunit zeta", "gene_name": "CCT6", "organism": "Yeast", "refseq_name": "chaperonin-containing T-complex subunit CCT6", "refseq_ac": [ { "id": "NP_010474", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010474", "type": "external" } ], "gene_names_uniprotkb": "CCT6; TCP20; TCP6; YD9395.21", "gene_names_refseq": "CCT6; HTR3; TCP20; TCP6", "protein_names_uniprotkb": "T-complex protein 1 subunit zeta; CCT-zeta; TCP-1-zeta", "protein_names_refseq": "chaperonin-containing T-complex subunit CCT6", "tax_id": 559292, "disease": "intrinsic cardiomyopathy (Disease Ontology:DOID:0060036)", "pathway": " (sce:YDR188W); (R-SCE-390471); (R-SCE-6814122)", "pathway_count": 3, "publication_count": 10, "publication_id_list": "18407956;21126336;22814378;23749301;24374639;32597660;33481703;33491328;8034610;9169867", "class_list": "", "function": "Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. In yeast may play a role in mitotic spindle formation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSH1", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity;GO:0140662 ATP-dependent protein folding chaperone", "go_cellular_component": "GO:0005832 chaperonin-containing T-complex", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P39079-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39102-1", "uniprot_id": [ { "id": "XDJ1_YEAST", "url": "https://www.uniprot.org/uniprot/P39102", "type": "external" } ], "mass": 51347.0, "length": 459, "protein_name": "DnaJ protein homolog XDJ1", "gene_name": "XDJ1", "organism": "Yeast", "refseq_name": "Xdj1p", "refseq_ac": [ { "id": "NP_013191", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013191", "type": "external" } ], "gene_names_uniprotkb": "XDJ1; L9449.3", "gene_names_refseq": "XDJ1", "protein_names_uniprotkb": "DnaJ protein homolog XDJ1", "protein_names_refseq": "Xdj1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR090W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;16689936;16823961;23749301;24374639;33491328;8045410;9169871", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY90;Q12014", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0051082 unfolded protein binding;GO:0001671 ATPase activator activity;GO:0030544 Hsp70 protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0006457 protein folding;GO:0030150 protein import into mitochondrial matrix", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P39102-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39106-1", "uniprot_id": [ { "id": "MNN1_YEAST", "url": "https://www.uniprot.org/uniprot/P39106", "type": "external" } ], "mass": 88529.0, "length": 762, "protein_name": "Alpha-1,3-mannosyltransferase MNN1", "gene_name": "MNN1", "organism": "Yeast", "refseq_name": "alpha-1,3-mannosyltransferase MNN1", "refseq_ac": [ { "id": "NP_010916", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010916", "type": "external" } ], "gene_names_uniprotkb": "MNN1", "gene_names_refseq": "MNN1", "protein_names_uniprotkb": "Alpha-1,3-mannosyltransferase MNN1; 2.4.1.-", "protein_names_refseq": "alpha-1,3-mannosyltransferase MNN1", "tax_id": 559292, "disease": "", "pathway": " (sce:YER001W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "14562106;24374639;8146181;9169868", "class_list": "glycogene;glycosyltransferase", "function": "Responsible for addition of the terminal mannose residues to the outer chain of core N-linked polysaccharides and to O-linked mannotriose. Implicated in late Golgi modifications., [UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 4, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D3DLP7", "ec_number_list": [], "go_molecular_function": "GO:0000033 alpha-1,3-mannosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0006493 protein O-linked glycosylation;GO:0006491 N-glycan processing", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P39106-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000011000.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39110-1", "uniprot_id": [ { "id": "CIN4_YEAST", "url": "https://www.uniprot.org/uniprot/P39110", "type": "external" } ], "mass": 22067.0, "length": 191, "protein_name": "GTP-binding protein CIN4", "gene_name": "CIN4", "organism": "Yeast", "refseq_name": "Arf family GTPase CIN4", "refseq_ac": [ { "id": "NP_013858", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013858", "type": "external" } ], "gene_names_uniprotkb": "CIN4; GTP1; UGX1; YM9375.07", "gene_names_refseq": "CIN4; GTP1; UGX1", "protein_names_uniprotkb": "GTP-binding protein CIN4; Chromosome instability protein 4", "protein_names_refseq": "Arf family GTPase CIN4", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR138W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;17322287;24374639;33491328;7874754;9169872", "class_list": "", "function": "Implicated in yeast microtubule function., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VZW1", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0015630 microtubule cytoskeleton", "go_biological_process": "GO:0006457 protein folding;GO:0007021 tubulin complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P39110-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39113-1", "uniprot_id": [ { "id": "CAT8_YEAST", "url": "https://www.uniprot.org/uniprot/P39113", "type": "external" } ], "mass": 160485.0, "length": 1433, "protein_name": "Regulatory protein CAT8", "gene_name": "CAT8", "organism": "Yeast", "refseq_name": "DNA-binding transcription factor CAT8", "refseq_ac": [ { "id": "NP_014007", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014007", "type": "external" } ], "gene_names_uniprotkb": "CAT8; MSP8; YM8021.06C", "gene_names_refseq": "CAT8; DIL1; MSP8", "protein_names_uniprotkb": "Regulatory protein CAT8", "protein_names_refseq": "DNA-binding transcription factor CAT8", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR280C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "15121831;18407956;19779198;23749301;24374639;33229814;33491328;7891685;9169872", "class_list": "", "function": "Activator of the gluconeogenic enzymes FBP1 and PCK1 genes., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 21, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 21, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 21, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 20, "binding_glycan_count": 0, "secondary_ac_list": "D6W0A7", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045722 positive regulation of gluconeogenesis;GO:2000876 positive regulation of glyoxylate cycle", "synthesized_glycan_count": 0, "hit_score": 3.2, "record_id": "P39113-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39525-1", "uniprot_id": [ { "id": "CEM1_YEAST", "url": "https://www.uniprot.org/uniprot/P39525", "type": "external" } ], "mass": 47555.0, "length": 442, "protein_name": "3-oxoacyl-[acyl-carrier-protein] synthase homolog", "gene_name": "CEM1", "organism": "Yeast", "refseq_name": "fatty acid synthase CEM1", "refseq_ac": [ { "id": "NP_010983", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010983", "type": "external" } ], "gene_names_uniprotkb": "CEM1", "gene_names_refseq": "CEM1", "protein_names_uniprotkb": "3-oxoacyl-[acyl-carrier-protein] synthase homolog; 2.3.1.41; Beta-ketoacyl-ACP synthase homolog", "protein_names_refseq": "fatty acid synthase CEM1", "tax_id": 559292, "disease": "", "pathway": " (sce:YER061C); (R-SCE-9837999)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "14562095;14562106;16823961;24374639;8412701;9169868", "class_list": "", "function": "Possibly involved in the synthesis of a specialized molecule, probably related to a fatty acid, which is essential for mitochondrial respiration. Is essential for oxygen uptake and the presence of cytochromes A and B., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLW6", "ec_number_list": [ { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "7.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.2.2", "type": "external" }, { "id": "2.3.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.1", "type": "external" }, { "id": "4.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.2", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "4.98.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.98.1.1", "type": "external" }, { "id": "1.1.1.100", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.100", "type": "external" }, { "id": "2.3.1.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.41", "type": "external" }, { "id": "2.3.1.86", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.86", "type": "external" }, { "id": "4.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.3", "type": "external" }, { "id": "1.2.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.2", "type": "external" }, { "id": "1.1.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.37", "type": "external" }, { "id": "1.2.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.1", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "1.2.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.4", "type": "external" }, { "id": "1.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.5", "type": "external" }, { "id": "6.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.5", "type": "external" }, { "id": "2.3.3.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.10", "type": "external" } ], "go_molecular_function": "GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006633 fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P39525-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39526-1", "uniprot_id": [ { "id": "LAA1_YEAST", "url": "https://www.uniprot.org/uniprot/P39526", "type": "external" } ], "mass": 229900.0, "length": 2014, "protein_name": "AP-1 accessory protein LAA1", "gene_name": "LAA1", "organism": "Yeast", "refseq_name": "AP-1 complex accessory protein LAA1", "refseq_ac": [ { "id": "NP_012328", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012328", "type": "external" } ], "gene_names_uniprotkb": "LAA1; HRD550; J0312", "gene_names_refseq": "LAA1", "protein_names_uniprotkb": "AP-1 accessory protein LAA1; Large AP-1 accessory protein 1", "protein_names_refseq": "AP-1 complex accessory protein LAA1", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL207C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10407277;14562095;14562106;16687571;16702403;24374639;30523155;33491328;7725802;7754713;8641269", "class_list": "", "function": "Involved in localization of clathrin adapter protein complex-1 (AP-1) and subsequent AP-1-mediated clathrin-coated vesicle cargo loading (PubMed:16687571, PubMed:30523155). In complex with LAA2, cooperates with the small GTPase ARF1 and the phosphatidyl-inositol-4-phosphate (PI4P) synthesis to confer temporal specificity to AP-1 recruitment (PubMed:30523155)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVY7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0030136 clathrin-coated vesicle;GO:0030139 endocytic vesicle", "go_biological_process": "GO:0006897 endocytosis;GO:0015031 protein transport;GO:0008104 intracellular protein localization;GO:0042147 retrograde transport, endosome to Golgi;GO:0035653 clathrin-coated vesicle cargo loading, AP-1-mediated", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P39526-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39535-1", "uniprot_id": [ { "id": "PHO90_YEAST", "url": "https://www.uniprot.org/uniprot/P39535", "type": "external" } ], "mass": 97689.0, "length": 881, "protein_name": "Low-affinity phosphate transporter PHO90", "gene_name": "PHO90", "organism": "Yeast", "refseq_name": "SPX domain-containing inorganic phosphate transporter", "refseq_ac": [ { "id": "NP_012337", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012337", "type": "external" } ], "gene_names_uniprotkb": "PHO90; J0336", "gene_names_refseq": "PHO90", "protein_names_uniprotkb": "Low-affinity phosphate transporter PHO90", "protein_names_refseq": "SPX domain-containing inorganic phosphate transporter", "tax_id": 559292, "disease": "alcohol-related neurodevelopmental disorder (Disease Ontology:DOID:0050667); developmental and epileptic encephalopathy 25 (Disease Ontology:DOID:0080453); Kohlschutter-Tonz syndrome (Disease Ontology:DOID:0111668); epilepsy (Disease Ontology:DOID:1826)", "pathway": " (sce:YJL198W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "11779791;12821119;14562106;20133652;21143198;24374639;32597660;33229814;33481703;33491328;7754713;8641269", "class_list": "", "function": "Low-affinity phosphate transporter involved in the control of cellular phosphate levels., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 4, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005315 phosphate transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0055085 transmembrane transport;GO:0006817 phosphate ion transport;GO:0006797 polyphosphate metabolic process;GO:2000185 regulation of phosphate transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P39535-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39543-1", "uniprot_id": [ { "id": "SOP4_YEAST", "url": "https://www.uniprot.org/uniprot/P39543", "type": "external" } ], "mass": 26598.0, "length": 234, "protein_name": "Protein SOP4", "gene_name": "SOP4", "organism": "Yeast", "refseq_name": "Sop4p", "refseq_ac": [ { "id": "NP_012343", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012343", "type": "external" } ], "gene_names_uniprotkb": "SOP4; J0351", "gene_names_refseq": "EMC7; SOP4", "protein_names_uniprotkb": "Protein SOP4; Suppressor of PMA1-7 protein 4", "protein_names_refseq": "Sop4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL192C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12230471;14562095;14562106;17322287;24374639;7754713;8641269;9265642", "class_list": "", "function": "Involved in the export of PMA1, possibly through the monitoring or assisting of PMA1 folding and acquisition of competence to enter vesicles., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VVZ9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0015031 protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P39543-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39547-1", "uniprot_id": [ { "id": "UIP3_YEAST", "url": "https://www.uniprot.org/uniprot/P39547", "type": "external" } ], "mass": 27117.0, "length": 235, "protein_name": "ULP1-interacting protein 3", "gene_name": "UIP3", "organism": "Yeast", "refseq_name": "DUP240 family protein UIP3", "refseq_ac": [ { "id": "NP_009414", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009414", "type": "external" } ], "gene_names_uniprotkb": "UIP3; FUN55", "gene_names_refseq": "UIP3", "protein_names_uniprotkb": "ULP1-interacting protein 3; DUP240 protein UIP3", "protein_names_refseq": "DUP240 family protein UIP3", "tax_id": 559292, "disease": "", "pathway": " (sce:YAR027W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "11056382;12101299;12872131;14562106;19779198;21126336;22106047;23749301;24374639;30516470;33491328;36800387;7731988", "class_list": "", "function": "Does not confer resistance to killer toxin K28, a protein-toxin encoded by the M28 virus that uses S.cerevisiae as a host., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPM9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005886 plasma membrane;GO:0031965 nuclear membrane;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P39547-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39548-1", "uniprot_id": [ { "id": "KTD1_YEAST", "url": "https://www.uniprot.org/uniprot/P39548", "type": "external" } ], "mass": 26458.0, "length": 234, "protein_name": "Protein-toxin resistance protein KTD1", "gene_name": "KTD1", "organism": "Yeast", "refseq_name": "DUP240 family protein", "refseq_ac": [ { "id": "NP_009415", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009415", "type": "external" } ], "gene_names_uniprotkb": "KTD1; FUN56", "gene_names_refseq": "KTD1", "protein_names_uniprotkb": "Protein-toxin resistance protein KTD1; Killer Toxin Defense 1", "protein_names_refseq": "DUP240 family protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YAR028W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "12101299;14557538;14562106;16847258;17563356;22106047;23749301;24374639;33481703;33491328;36800387;7731988", "class_list": "", "function": "Confers resistance to killer toxin K28, a protein-toxin encoded by the M28 virus that uses S.cerevisiae as a host (PubMed:36800387). Probably acts against K28 after endocytosis of the protein-toxin (PubMed:36800387)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPN0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0010008 endosome membrane;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0097237 cellular response to toxic substance", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P39548-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39551-1", "uniprot_id": [ { "id": "PRM9_YEAST", "url": "https://www.uniprot.org/uniprot/P39551", "type": "external" } ], "mass": 35073.0, "length": 298, "protein_name": "Pheromone-regulated membrane protein 9", "gene_name": "PRM9", "organism": "Yeast", "refseq_name": "pheromone-regulated DUP240 family protein PRM9", "refseq_ac": [ { "id": "NP_009418", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009418", "type": "external" } ], "gene_names_uniprotkb": "PRM9; FUN58", "gene_names_refseq": "PRM9", "protein_names_uniprotkb": "Pheromone-regulated membrane protein 9; DUP240 protein PRM9", "protein_names_refseq": "pheromone-regulated DUP240 family protein PRM9", "tax_id": 559292, "disease": "", "pathway": " (sce:YAR031W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11062271;12101299;12925749;14562106;16847258;24374639;7731988", "class_list": "", "function": "May be involved in endoplasmic reticulum exit trafficking of proteins., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPN2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane", "go_biological_process": "GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P39551-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39677-1", "uniprot_id": [ { "id": "RRF2M_YEAST", "url": "https://www.uniprot.org/uniprot/P39677", "type": "external" } ], "mass": 91283.0, "length": 819, "protein_name": "Ribosome-releasing factor 2, mitochondrial", "gene_name": "MEF2", "organism": "Yeast", "refseq_name": "mitochondrial elongation factor MEF2", "refseq_ac": [ { "id": "NP_012433", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012433", "type": "external" } ], "gene_names_uniprotkb": "MEF2; D819; J0826", "gene_names_refseq": "MEF2", "protein_names_uniprotkb": "Ribosome-releasing factor 2, mitochondrial; EF-G2mt; Elongation factor G 2, mitochondrial; RRF2mt; mEF-G 2", "protein_names_refseq": "mitochondrial elongation factor MEF2", "tax_id": 559292, "disease": "combined oxidative phosphorylation deficiency 39 (Disease Ontology:DOID:0111475)", "pathway": " (sce:YJL102W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;14576278;21414316;24374639;33481703;33491328;7483851;8641269", "class_list": "", "function": "Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation (By similarity). Required for respiratory growth and essential for mitochondrial genome maintenance., [UniProtKB, HAMAP, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW82", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0032790 ribosome disassembly;GO:0051881 regulation of mitochondrial membrane potential;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P39677-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39682-1", "uniprot_id": [ { "id": "PRP39_YEAST", "url": "https://www.uniprot.org/uniprot/P39682", "type": "external" } ], "mass": 74748.0, "length": 629, "protein_name": "Pre-mRNA-processing factor 39", "gene_name": "PRP39", "organism": "Yeast", "refseq_name": "Prp39p", "refseq_ac": [ { "id": "NP_013667", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013667", "type": "external" } ], "gene_names_uniprotkb": "PRP39; YM9827.06", "gene_names_refseq": "PRP39", "protein_names_uniprotkb": "Pre-mRNA-processing factor 39", "protein_names_refseq": "Prp39p", "tax_id": 559292, "disease": "", "pathway": " (sce:YML046W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;17322287;24374639;33491328;8196608;9012791;9169872", "class_list": "", "function": "Function prior to stable branch point recognition by the U1 snRNP particle to facilitate or stabilize the U1 snRNP/5'-splice site interaction. Has a direct role in the assembly or function of a catalytically active spliceosome., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZC9;E9P8Z1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0005634 nucleus;GO:0000243 commitment complex;GO:0071004 U2-type prespliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0000395 mRNA 5'-splice site recognition", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P39682-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39684-1", "uniprot_id": [ { "id": "PES4_YEAST", "url": "https://www.uniprot.org/uniprot/P39684", "type": "external" } ], "mass": 70842.0, "length": 611, "protein_name": "Protein PES4", "gene_name": "PES4", "organism": "Yeast", "refseq_name": "Pes4p", "refseq_ac": [ { "id": "NP_116678", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116678", "type": "external" } ], "gene_names_uniprotkb": "PES4", "gene_names_refseq": "PES4", "protein_names_uniprotkb": "Protein PES4; DNA polymerase epsilon suppressor 4", "protein_names_refseq": "Pes4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YFR023W); (R-SCE-156827); (R-SCE-429947); (R-SCE-72649); (R-SCE-975956); (R-SCE-975957)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "24374639;7670463", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTQ3", "ec_number_list": [], "go_molecular_function": "GO:0003730 mRNA 3'-UTR binding;GO:0008143 poly(A) binding;GO:0008266 poly(U) RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0010494 cytoplasmic stress granule;GO:1990904 ribonucleoprotein complex;GO:0005628 prospore membrane", "go_biological_process": "GO:0016071 mRNA metabolic process;GO:0010609 mRNA localization resulting in post-transcriptional regulation of gene expression;GO:0006417 regulation of translation;GO:0043934 sporulation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P39684-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39692-1", "uniprot_id": [ { "id": "MET10_YEAST", "url": "https://www.uniprot.org/uniprot/P39692", "type": "external" } ], "mass": 114829.0, "length": 1035, "protein_name": "Sulfite reductase [NADPH] flavoprotein component", "gene_name": "MET10", "organism": "Yeast", "refseq_name": "sulfite reductase subunit alpha", "refseq_ac": [ { "id": "NP_116686", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116686", "type": "external" } ], "gene_names_uniprotkb": "MET10", "gene_names_refseq": "MET10", "protein_names_uniprotkb": "Sulfite reductase [NADPH] flavoprotein component; 1.8.1.2", "protein_names_refseq": "sulfite reductase subunit alpha", "tax_id": 559292, "disease": "", "pathway": " (sce:YFR030W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562106;24374639;33491328;6751400;7670463;7698648;7788524;7928966;8686381", "class_list": "", "function": "This enzyme catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VTR0;Q12683", "ec_number_list": [ { "id": "1.8.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.1.2", "type": "external" } ], "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0016491 oxidoreductase activity;GO:0010181 FMN binding;GO:0004783 sulfite reductase (NADPH) activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0009337 sulfite reductase complex (NADPH)", "go_biological_process": "GO:0000097 sulfur amino acid biosynthetic process;GO:0070814 hydrogen sulfide biosynthetic process;GO:0000103 sulfate assimilation", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P39692-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39708-1", "uniprot_id": [ { "id": "DHE5_YEAST", "url": "https://www.uniprot.org/uniprot/P39708", "type": "external" } ], "mass": 49627.0, "length": 457, "protein_name": "NADP-specific glutamate dehydrogenase 2", "gene_name": "GDH3", "organism": "Yeast", "refseq_name": "glutamate dehydrogenase (NADP(+)) GDH3", "refseq_ac": [ { "id": "NP_009339", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009339", "type": "external" } ], "gene_names_uniprotkb": "GDH3; FUN51", "gene_names_refseq": "FUN51; GDH3", "protein_names_uniprotkb": "NADP-specific glutamate dehydrogenase 2; 1.4.1.4; NADP-GDH 2; NADP-dependent glutamate dehydrogenase 2", "protein_names_refseq": "glutamate dehydrogenase (NADP(+)) GDH3", "tax_id": 559292, "disease": "familial hyperinsulinemic hypoglycemia 6 (Disease Ontology:DOID:0070217); Alzheimer's disease (Disease Ontology:DOID:10652); hepatic encephalopathy (Disease Ontology:DOID:13413); childhood absence epilepsy (Disease Ontology:DOID:1825); hyperinsulinism (Disease Ontology:DOID:2018); brain ischemia (Disease Ontology:DOID:2316); temporal lobe epilepsy (Disease Ontology:DOID:3328); fascioliasis (Disease Ontology:DOID:885); hypoglycemia (Disease Ontology:DOID:9993)", "pathway": " (sce:YAL062W)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "24374639;7731988", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPF7", "ec_number_list": [ { "id": "1.4.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.1.4", "type": "external" } ], "go_molecular_function": "GO:0004354 glutamate dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006537 glutamate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P39708-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39709-1", "uniprot_id": [ { "id": "SEO1_YEAST", "url": "https://www.uniprot.org/uniprot/P39709", "type": "external" } ], "mass": 68842.0, "length": 593, "protein_name": "Probable transporter SEO1", "gene_name": "SEO1", "organism": "Yeast", "refseq_name": "putative permease SEO1", "refseq_ac": [ { "id": "NP_009333", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009333", "type": "external" } ], "gene_names_uniprotkb": "SEO1", "gene_names_refseq": "SEO1", "protein_names_uniprotkb": "Probable transporter SEO1", "protein_names_refseq": "putative permease SEO1", "tax_id": 559292, "disease": "autosomal dominant nonsyndromic deafness 25 (Disease Ontology:DOID:0110555); lysosomal storage disease (Disease Ontology:DOID:3211); sialuria (Disease Ontology:DOID:3659)", "pathway": " (sce:YAL067C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "16847258;19779198;20702584;24374639;33481703;33491328;7731988", "class_list": "", "function": "Not known; suppressor of sulfoxide ethionine resistance., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPF0", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0071916 dipeptide transmembrane transporter activity;GO:0015124 allantoate transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0055085 transmembrane transport;GO:0042938 dipeptide transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P39709-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39712-1", "uniprot_id": [ { "id": "FLO9_YEAST", "url": "https://www.uniprot.org/uniprot/P39712", "type": "external" } ], "mass": 138073.0, "length": 1322, "protein_name": "Flocculation protein FLO9", "gene_name": "FLO9", "organism": "Yeast", "refseq_name": "flocculin FLO9", "refseq_ac": [ { "id": "NP_009338", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009338", "type": "external" } ], "gene_names_uniprotkb": "FLO9", "gene_names_refseq": "FLO9", "protein_names_uniprotkb": "Flocculation protein FLO9; Flocculin-9", "protein_names_refseq": "flocculin FLO9", "tax_id": 559292, "disease": "", "pathway": " (sce:YAL063C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15470092;16086015;24374639;7502576;7731988", "class_list": "", "function": "Cell wall protein that participates directly in adhesive cell-cell interactions during yeast flocculation, a reversible, asexual and Ca(2+)-dependent process in which cells adhere to form aggregates (flocs) consisting of thousands of cells. The lectin-like protein sticks out of the cell wall of flocculent cells and selectively binds mannose residues in the cell walls of adjacent cells., [UniProtKB]", "predicted_glycosites": 16, "predicted_n_glycosites": 16, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 16, "binding_glycan_count": 0, "secondary_ac_list": "D6VPF6", "ec_number_list": [], "go_molecular_function": "GO:0005537 D-mannose binding", "go_cellular_component": "GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0031589 cell-substrate adhesion;GO:0000128 flocculation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P39712-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39713-1", "uniprot_id": [ { "id": "BDH2_YEAST", "url": "https://www.uniprot.org/uniprot/P39713", "type": "external" } ], "mass": 46099.0, "length": 417, "protein_name": "Probable diacetyl reductase [(R)-acetoin forming] 2", "gene_name": "BDH2", "organism": "Yeast", "refseq_name": "putative dehydrogenase BDH2", "refseq_ac": [ { "id": "NP_009340", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009340", "type": "external" } ], "gene_names_uniprotkb": "BDH2; FUN50", "gene_names_refseq": "BDH2", "protein_names_uniprotkb": "Probable diacetyl reductase [(R)-acetoin forming] 2; 1.1.1.303", "protein_names_refseq": "putative dehydrogenase BDH2", "tax_id": 559292, "disease": "", "pathway": " (sce:YAL061W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11470516;14562095;14562106;14871952;17322287;24374639;33491328;7731988", "class_list": "", "function": "Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPF8", "ec_number_list": [ { "id": "1.1.1.303", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.303", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000721 (R,R)-butanediol dehydrogenase activity;GO:0052587 diacetyl reductase ((R)-acetoin forming) (NAD+) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0034079 butanediol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P39713-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39715-1", "uniprot_id": [ { "id": "ECM1_YEAST", "url": "https://www.uniprot.org/uniprot/P39715", "type": "external" } ], "mass": 23891.0, "length": 212, "protein_name": "Shuttling pre-60S factor ECM1", "gene_name": "ECM1", "organism": "Yeast", "refseq_name": "Ecm1p", "refseq_ac": [ { "id": "NP_009342", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009342", "type": "external" } ], "gene_names_uniprotkb": "ECM1; SIM1", "gene_names_refseq": "ECM1", "protein_names_uniprotkb": "Shuttling pre-60S factor ECM1; Extracellular mutant protein 1; Protein SIM1", "protein_names_refseq": "Ecm1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YAL059W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "11583615;14562095;14562106;17322287;17563356;19779198;20348449;23749301;24374639;33229814;33481703;33491328;7731988", "class_list": "", "function": "Pre-ribosomal factor involved in 60S ribosomal protein subunit export from the nucleus., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VPG0;E9P8V4", "ec_number_list": [], "go_molecular_function": "GO:1990275 preribosome binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0030687 preribosome, large subunit precursor", "go_biological_process": "GO:0000055 ribosomal large subunit export from nucleus", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P39715-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39734-1", "uniprot_id": [ { "id": "HPH2_YEAST", "url": "https://www.uniprot.org/uniprot/P39734", "type": "external" } ], "mass": 58750.0, "length": 528, "protein_name": "Protein HPH2", "gene_name": "FRT2", "organism": "Yeast", "refseq_name": "Frt2p", "refseq_ac": [ { "id": "NP_009374", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009374", "type": "external" } ], "gene_names_uniprotkb": "FRT2; HPH2", "gene_names_refseq": "FRT2; HPH2", "protein_names_uniprotkb": "Protein HPH2; Functionally related to TCP1 protein 2; High pH protein 2", "protein_names_refseq": "Frt2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YAL028W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14574415;15189990;24374639;33491328;7731988", "class_list": "", "function": "Required for growth under high NaCl, alkaline pH and cell wall stress., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPJ0;P39733", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0071469 cellular response to alkaline pH;GO:0071472 cellular response to salt stress;GO:0031204 post-translational protein targeting to membrane, translocation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P39734-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39924-1", "uniprot_id": [ { "id": "HXT13_YEAST", "url": "https://www.uniprot.org/uniprot/P39924", "type": "external" } ], "mass": 62734.0, "length": 564, "protein_name": "Hexose transporter HXT13", "gene_name": "HXT13", "organism": "Yeast", "refseq_name": "hexose transporter HXT13", "refseq_ac": [ { "id": "NP_010845", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010845", "type": "external" } ], "gene_names_uniprotkb": "HXT13; HXT8", "gene_names_refseq": "HLT1; HXT13", "protein_names_uniprotkb": "Hexose transporter HXT13", "protein_names_refseq": "hexose transporter HXT13", "tax_id": 559292, "disease": "", "pathway": " (sce:YEL069C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "16847258;17322287;24374639;9169868", "class_list": "", "function": "Probable glucose transporter., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLI2", "ec_number_list": [], "go_molecular_function": "GO:0005353 fructose transmembrane transporter activity;GO:0015578 mannose transmembrane transporter activity;GO:0005351 carbohydrate:proton symporter activity;GO:0055056 D-glucose transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane", "go_biological_process": "GO:0015797 mannitol transmembrane transport;GO:0008643 carbohydrate transport;GO:0008645 hexose transmembrane transport;GO:0015795 sorbitol transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P39924-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39932-1", "uniprot_id": [ { "id": "STL1_YEAST", "url": "https://www.uniprot.org/uniprot/P39932", "type": "external" } ], "mass": 63532.0, "length": 569, "protein_name": "Sugar transporter STL1", "gene_name": "STL1", "organism": "Yeast", "refseq_name": "glucose-inactivated glycerol proton symporter STL1", "refseq_ac": [ { "id": "NP_010825", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010825", "type": "external" } ], "gene_names_uniprotkb": "STL1; D9719.39", "gene_names_refseq": "STL1", "protein_names_uniprotkb": "Sugar transporter STL1", "protein_names_refseq": "glucose-inactivated glycerol proton symporter STL1", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR536W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "16847258;17322287;24374639;8076821;9169867", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VTF6;E9P950", "ec_number_list": [], "go_molecular_function": "GO:0015295 solute:proton symporter activity;GO:0005351 carbohydrate:proton symporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0055085 transmembrane transport;GO:0015793 glycerol transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P39932-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39933-1", "uniprot_id": [ { "id": "TF3A_YEAST", "url": "https://www.uniprot.org/uniprot/P39933", "type": "external" } ], "mass": 50027.0, "length": 429, "protein_name": "Transcription factor IIIA", "gene_name": "PZF1", "organism": "Yeast", "refseq_name": "Pzf1p", "refseq_ac": [ { "id": "NP_015512", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015512", "type": "external" } ], "gene_names_uniprotkb": "PZF1; P9677.9; TFC2; TFIIIA", "gene_names_refseq": "PZF1; TFC2", "protein_names_uniprotkb": "Transcription factor IIIA; Putative zinc finger protein 1; TFIIIA", "protein_names_refseq": "Pzf1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR186C); (R-SCE-6807505)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "14562106;1570325;1737784;18407956;24374639;32597660;33481703;33491328;9169875", "class_list": "", "function": "Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4I6", "ec_number_list": [], "go_molecular_function": "GO:0001010 RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity;GO:0001002 RNA polymerase III type 1 promoter sequence-specific DNA binding;GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0042791 5S class rRNA transcription by RNA polymerase III;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P39933-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39937-1", "uniprot_id": [ { "id": "PAC2_YEAST", "url": "https://www.uniprot.org/uniprot/P39937", "type": "external" } ], "mass": 59258.0, "length": 518, "protein_name": "Protein PAC2", "gene_name": "PAC2", "organism": "Yeast", "refseq_name": "Pac2p", "refseq_ac": [ { "id": "NP_010922", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010922", "type": "external" } ], "gene_names_uniprotkb": "PAC2", "gene_names_refseq": "PAC2", "protein_names_uniprotkb": "Protein PAC2", "protein_names_refseq": "Pac2p", "tax_id": 559292, "disease": "hypoparathyroidism-retardation-dysmorphism syndrome (Disease Ontology:DOID:0060348); Kenny-Caffey syndrome type 1 (Disease Ontology:DOID:0080722); hypoparathyroidism (Disease Ontology:DOID:11199)", "pathway": " (sce:YER007W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;24374639;33229814;9169868;9215891", "class_list": "", "function": "Required for viability in the absence of the kinesin-related CIN8 mitotic motor. Seems to be involved in the assembly of alpha-tubulin., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D3DLQ3", "ec_number_list": [], "go_molecular_function": "GO:0043014 alpha-tubulin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule", "go_biological_process": "GO:0006457 protein folding;GO:0000226 microtubule cytoskeleton organization;GO:0007021 tubulin complex assembly;GO:0007023 post-chaperonin tubulin folding pathway", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P39937-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39938-1", "uniprot_id": [ { "id": "RS26A_YEAST", "url": "https://www.uniprot.org/uniprot/P39938", "type": "external" } ], "mass": 13505.0, "length": 119, "protein_name": "Small ribosomal subunit protein eS26A", "gene_name": "RPS26A", "organism": "Yeast", "refseq_name": "40S ribosomal protein eS26 RPS26A", "refseq_ac": [ { "id": "NP_011326", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011326", "type": "external" } ], "gene_names_uniprotkb": "RPS26A; G1355; RPS26", "gene_names_refseq": "RPS26A; RPS26", "protein_names_uniprotkb": "Small ribosomal subunit protein eS26A; 40S ribosomal protein S26-A", "protein_names_refseq": "40S ribosomal protein eS26 RPS26A", "tax_id": 559292, "disease": "Diamond-Blackfan anemia 10 (Disease Ontology:DOID:0111888); Diamond-Blackfan anemia (Disease Ontology:DOID:1339)", "pathway": " (sce:YGL189C); (R-SCE-156827); (R-SCE-1799339); (R-SCE-6791226); (R-SCE-72649); (R-SCE-72689); (R-SCE-72695); (R-SCE-72702); (R-SCE-72706); (R-SCE-975956); (R-SCE-975957); (R-SCE-9954714)", "pathway_count": 12, "publication_count": 17, "publication_id_list": "10688190;12837249;14562095;14562106;15665377;17244705;17287358;22096102;22218487;24374639;24524803;33481703;33491328;7821815;9046087;9169869;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A2TBN5;D6VTW5", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0030686 90S preribosome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0000054 ribosomal subunit export from nucleus;GO:0002181 cytoplasmic translation;GO:0042255 ribosome assembly;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P39938-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39939-1", "uniprot_id": [ { "id": "RS26B_YEAST", "url": "https://www.uniprot.org/uniprot/P39939", "type": "external" } ], "mass": 13447.0, "length": 119, "protein_name": "Small ribosomal subunit protein eS26B", "gene_name": "RPS26B", "organism": "Yeast", "refseq_name": "40S ribosomal protein eS26 RPS26B", "refseq_ac": [ { "id": "NP_011057", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011057", "type": "external" } ], "gene_names_uniprotkb": "RPS26B", "gene_names_refseq": "RPS26B", "protein_names_uniprotkb": "Small ribosomal subunit protein eS26B; 40S ribosomal protein S26-B", "protein_names_refseq": "40S ribosomal protein eS26 RPS26B", "tax_id": 559292, "disease": "Diamond-Blackfan anemia 10 (Disease Ontology:DOID:0111888); Diamond-Blackfan anemia (Disease Ontology:DOID:1339)", "pathway": " (sce:YER131W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "10688190;12837249;14562095;14562106;15665377;17244705;17322287;18407956;19779198;22096102;22218487;23749301;24374639;24524803;32597660;33481703;33491328;9169868;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A2TBN5;D3DM37;Q6B2E8", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0030686 90S preribosome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0000054 ribosomal subunit export from nucleus;GO:0002181 cytoplasmic translation;GO:0042255 ribosome assembly;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P39939-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39944-1", "uniprot_id": [ { "id": "UBP5_YEAST", "url": "https://www.uniprot.org/uniprot/P39944", "type": "external" } ], "mass": 92261.0, "length": 805, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 5", "gene_name": "UBP5", "organism": "Yeast", "refseq_name": "putative ubiquitin-specific protease UBP5", "refseq_ac": [ { "id": "NP_011071", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011071", "type": "external" } ], "gene_names_uniprotkb": "UBP5", "gene_names_refseq": "UBP5", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 5; 3.4.19.12; Deubiquitinating enzyme 5; Ubiquitin thioesterase 5; Ubiquitin-specific-processing protease 5", "protein_names_refseq": "putative ubiquitin-specific protease UBP5", "tax_id": 559292, "disease": "ACTH-secreting pituitary adenoma (Disease Ontology:DOID:7004)", "pathway": " (sce:YER144C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562106;23749301;24374639;32597660;33229814;33481703;33491328;7871889;9169868", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D3DM51", "ec_number_list": [], "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0000131 incipient cellular bud site;GO:0005935 cellular bud neck", "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P39944-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39953-1", "uniprot_id": [ { "id": "YEA6_YEAST", "url": "https://www.uniprot.org/uniprot/P39953", "type": "external" } ], "mass": 36961.0, "length": 335, "protein_name": "Mitochondrial nicotinamide adenine dinucleotide transporter 2", "gene_name": "YEA6", "organism": "Yeast", "refseq_name": "NAD+ transporter", "refseq_ac": [ { "id": "NP_010910", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010910", "type": "external" } ], "gene_names_uniprotkb": "YEA6; NDT2", "gene_names_refseq": "NDT2; YEA6", "protein_names_uniprotkb": "Mitochondrial nicotinamide adenine dinucleotide transporter 2; Mitochondrial NAD(+) transporter 2", "protein_names_refseq": "NAD+ transporter", "tax_id": 559292, "disease": "", "pathway": " (sce:YEL006W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;16291748;17563356;24374639;32906142;9169868;9178508", "class_list": "", "function": "Mitochondrial inner membrane carrier protein that mediates the import of NAD(+) into mitochondria (PubMed:16291748, PubMed:32906142). Can transport NAD(+) by unidirectional transport or by exchange with intramitochondrially generated dAMP and dGMP (PubMed:16291748). Also able to transport NAD(+) by exchange with AMP, GMP or deamido-NAD (+) in vitro (PubMed:16291748)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLP1", "ec_number_list": [], "go_molecular_function": "GO:0051724 NAD transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:1990549 mitochondrial NAD transmembrane transport;GO:0035352 NAD transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P39953-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39954-1", "uniprot_id": [ { "id": "SAHH_YEAST", "url": "https://www.uniprot.org/uniprot/P39954", "type": "external" } ], "mass": 49126.0, "length": 449, "protein_name": "Adenosylhomocysteinase", "gene_name": "SAH1", "organism": "Yeast", "refseq_name": "adenosylhomocysteinase", "refseq_ac": [ { "id": "NP_010961", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010961", "type": "external" } ], "gene_names_uniprotkb": "SAH1", "gene_names_refseq": "SAH1", "protein_names_uniprotkb": "Adenosylhomocysteinase; 3.13.2.1; AdoHcyase; S-adenosyl-L-homocysteine hydrolase", "protein_names_refseq": "adenosylhomocysteinase", "tax_id": 559292, "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); hypermethioninemia with deficiency of S-adenosylhomocysteine hydrolase (Disease Ontology:DOID:0111039); abdominal aortic aneurysm (Disease Ontology:DOID:7693); pyridoxine deficiency anemia (Disease Ontology:DOID:8455); hyperhomocysteinemia (Disease Ontology:DOID:9279); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (sce:YER043C); (R-SCE-156581); (R-SCE-1614635)", "pathway_count": 3, "publication_count": 15, "publication_id_list": "17287358;17322287;17330950;18407956;19779198;19795423;19823750;20702584;22106047;22814378;23749301;24374639;33481703;33491328;9169868", "class_list": "", "function": "Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 16, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLU3", "ec_number_list": [ { "id": "3.13.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.13.2.1", "type": "external" } ], "go_molecular_function": "GO:0004013 adenosylhomocysteinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006641 triglyceride metabolic process;GO:0006656 phosphatidylcholine biosynthetic process;GO:0006730 one-carbon metabolic process;GO:0033353 S-adenosylmethionine cycle", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P39954-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39961-1", "uniprot_id": [ { "id": "TOG1_YEAST", "url": "https://www.uniprot.org/uniprot/P39961", "type": "external" } ], "mass": 91077.0, "length": 794, "protein_name": "Transcription factor TOG1", "gene_name": "TOG1", "organism": "Yeast", "refseq_name": "Tog1p", "refseq_ac": [ { "id": "NP_011111", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011111", "type": "external" } ], "gene_names_uniprotkb": "TOG1", "gene_names_refseq": "TOG1", "protein_names_uniprotkb": "Transcription factor TOG1; Transcriptional regulator of oleate 1", "protein_names_refseq": "Tog1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER184C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11353088;24374639;24998441;33229814;9169868", "class_list": "", "function": "Transcriptional activator required for growth on non-fermentable carbon sources and that regulates genes involved in fatty acid utilization (PubMed:11353088, PubMed:24998441). Acts as a direct activator that binds the promoters of oleate utilizing genes, encoded key enzymes in beta-oxidation and NADPH regeneration (POX1, FOX2,POT1 and IDP2), the glyoxylate shunt (MLS1 and ICL1), and gluconeogenesis (PCK1 and FBP1) (PubMed:24998441). Also regulates the abundance of peroxisomes that are vital for fatty acid oxidation (PubMed:24998441)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D3DM93", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P39961-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39965-1", "uniprot_id": [ { "id": "SYPM_YEAST", "url": "https://www.uniprot.org/uniprot/P39965", "type": "external" } ], "mass": 65880.0, "length": 576, "protein_name": "Probable proline--tRNA ligase, mitochondrial", "gene_name": "AIM10", "organism": "Yeast", "refseq_name": "putative proline--tRNA ligase AIM10", "refseq_ac": [ { "id": "NP_011010", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011010", "type": "external" } ], "gene_names_uniprotkb": "AIM10", "gene_names_refseq": "AIM10", "protein_names_uniprotkb": "Probable proline--tRNA ligase, mitochondrial; 6.1.1.15; Altered inheritance rate of mitochondria protein 10; ProRS; Prolyl-tRNA synthetase", "protein_names_refseq": "putative proline--tRNA ligase AIM10", "tax_id": 559292, "disease": "developmental and epileptic encephalopathy 75 (Disease Ontology:DOID:0112211)", "pathway": " (sce:YER087W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;16823961;17287358;21126336;24374639;33491328;9169868", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLZ3", "ec_number_list": [ { "id": "6.1.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.15", "type": "external" } ], "go_molecular_function": "GO:0004827 proline-tRNA ligase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006433 prolyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P39965-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39967-1", "uniprot_id": [ { "id": "UBP9_YEAST", "url": "https://www.uniprot.org/uniprot/P39967", "type": "external" } ], "mass": 86244.0, "length": 754, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 9", "gene_name": "UBP9", "organism": "Yeast", "refseq_name": "putative ubiquitin-specific protease UBP9", "refseq_ac": [ { "id": "NP_011024", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011024", "type": "external" } ], "gene_names_uniprotkb": "UBP9", "gene_names_refseq": "UBP9", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 9; 3.4.19.12; Deubiquitinating enzyme 9; Ubiquitin thioesterase 9; Ubiquitin-specific-processing protease 9", "protein_names_refseq": "putative ubiquitin-specific protease UBP9", "tax_id": 559292, "disease": "", "pathway": " (sce:YER098W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;22031224;22218487;24374639;32597660;33481703;33491328;9169868", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, 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deubiquitination;GO:0031647 regulation of protein stability", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P39967-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39980-1", "uniprot_id": [ { "id": "SIT1_YEAST", "url": "https://www.uniprot.org/uniprot/P39980", "type": "external" } ], "mass": 70562.0, "length": 628, "protein_name": "Siderophore iron transporter 1", "gene_name": "SIT1", "organism": "Yeast", "refseq_name": "siderophore transporter", "refseq_ac": [ { "id": "NP_010849", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010849", "type": "external" } ], "gene_names_uniprotkb": "SIT1; ARN3", "gene_names_refseq": "ARN3; SIT1", "protein_names_uniprotkb": "Siderophore iron transporter 1; Ferrioxamine B permease; Siderophore iron transporter ARN3", "protein_names_refseq": "siderophore transporter", "tax_id": 559292, "disease": "", "pathway": " (sce:YEL065W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10744769;10748025;17322287;24374639;33481703;9169868;9884238", "class_list": "", "function": "Involved in the transport of siderophore ferrioxamine B and so has a role in iron homeostasis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLI5;E9P951", "ec_number_list": [], "go_molecular_function": "GO:0015343 siderophore-iron transmembrane transporter activity;GO:0015344 siderophore uptake transmembrane transporter activity", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle;GO:0010008 endosome membrane;GO:0005774 vacuolar membrane", "go_biological_process": "GO:0055085 transmembrane transport;GO:0006879 intracellular iron ion homeostasis;GO:0015891 siderophore transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P39980-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39981-1", "uniprot_id": [ { "id": "AVT2_YEAST", "url": "https://www.uniprot.org/uniprot/P39981", "type": "external" } ], "mass": 53324.0, "length": 480, "protein_name": "Vacuolar amino acid transporter 2", "gene_name": "AVT2", "organism": "Yeast", "refseq_name": "Avt2p", "refseq_ac": [ { "id": "NP_010850", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010850", "type": "external" } ], "gene_names_uniprotkb": "AVT2", "gene_names_refseq": "AVT2", "protein_names_uniprotkb": "Vacuolar amino acid transporter 2", "protein_names_refseq": "Avt2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YEL064C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11274162;15905473;24374639;33491328;9169868", "class_list": "", "function": "Probable amino acid transporter of unknown specificity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLI6;Q2VQX2", "ec_number_list": [], "go_molecular_function": "GO:0015179 L-amino acid transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0005774 vacuolar membrane", "go_biological_process": "GO:0003333 amino acid transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P39981-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39982-1", "uniprot_id": [ { "id": "HHY1_YEAST", "url": "https://www.uniprot.org/uniprot/P39982", "type": "external" } ], "mass": 11341.0, "length": 102, "protein_name": "Hypersensitivity to hygromycin-B protein 1", "gene_name": "HHY1", "organism": "Yeast", "refseq_name": "Hhy1p", "refseq_ac": [ { "id": "NP_001381963", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001381963", "type": "external" } ], "gene_names_uniprotkb": "HHY1", "gene_names_refseq": "HHY1", "protein_names_uniprotkb": "Hypersensitivity to hygromycin-B protein 1", "protein_names_refseq": "Hhy1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YEL059W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "16847258;20043226;24374639;9169868", "class_list": "", "function": "Involved in vacuolar trafficking., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8D9PCP9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P39982-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39983-1", "uniprot_id": [ { "id": "SDD1_YEAST", "url": "https://www.uniprot.org/uniprot/P39983", "type": "external" } ], "mass": 27229.0, "length": 233, "protein_name": "Uncharacterized protein YEL057C", "gene_name": "SDD1", "organism": "Yeast", "refseq_name": "Sdd1p", "refseq_ac": [ { "id": "NP_010857", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010857", "type": "external" } ], "gene_names_uniprotkb": "SDD1", "gene_names_refseq": "SDD1", "protein_names_uniprotkb": "Uncharacterized protein YEL057C; Suppressor of degenerative death", "protein_names_refseq": "Sdd1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YEL057C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "17322287;24374639;32203490;9169868", "class_list": "", "function": "Acts as an endogenous target of the ribosome quality control (RQC) pathway (PubMed:32203490). During translation, the nascent chain has a propensity to stall ribosomes, thereby stimulating activation of the RQC pathway (PubMed:32203490)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 16, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLJ3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P39983-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39987-1", "uniprot_id": [ { "id": "HSP7E_YEAST", "url": "https://www.uniprot.org/uniprot/P39987", "type": "external" } ], "mass": 70084.0, "length": 644, "protein_name": "Heat shock protein SSC3, mitochondrial", "gene_name": "ECM10", "organism": "Yeast", "refseq_name": "Hsp70 family ATPase ECM10", "refseq_ac": [ { "id": "NP_010884", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010884", "type": "external" } ], "gene_names_uniprotkb": "ECM10; SSC3", "gene_names_refseq": "ECM10; SSC3", "protein_names_uniprotkb": "Heat shock protein SSC3, mitochondrial; Extracellular mutant protein 10", "protein_names_refseq": "Hsp70 family ATPase ECM10", "tax_id": 559292, "disease": "autosomal dominant sideroblastic anemia 4 (Disease Ontology:DOID:0060335); Parkinsonism (Disease Ontology:DOID:0080855); Alzheimer's disease (Disease Ontology:DOID:10652); Parkinson's disease (Disease Ontology:DOID:14330); brain ischemia (Disease Ontology:DOID:2316); rheumatoid arthritis (Disease Ontology:DOID:7148)", "pathway": " (sce:YEL030W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11150530;12943685;21126336;23749301;24374639;33491328;9169868", "class_list": "", "function": "Plays a role in facilitating the assembly of some protein complexes inside the mitochondria. It may initiate the events that lead to refolding of imported precursors in the matrix space., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLL9", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity;GO:0031072 heat shock protein binding;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0042645 mitochondrial nucleoid", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0006626 protein targeting to mitochondrion;GO:0042026 protein refolding", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P39987-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39988-1", "uniprot_id": [ { "id": "BUD16_YEAST", "url": "https://www.uniprot.org/uniprot/P39988", "type": "external" } ], "mass": 35559.0, "length": 312, "protein_name": "Putative pyridoxal kinase BUD16", "gene_name": "BUD16", "organism": "Yeast", "refseq_name": "putative pyridoxal kinase BUD16", "refseq_ac": [ { "id": "NP_010885", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010885", "type": "external" } ], "gene_names_uniprotkb": "BUD16", "gene_names_refseq": "BUD16", "protein_names_uniprotkb": "Putative pyridoxal kinase BUD16; 2.7.1.35; Bud site selection protein 16", "protein_names_refseq": "putative pyridoxal kinase BUD16", "tax_id": 559292, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (sce:YEL029C); (R-SCE-6798695); (R-SCE-964975)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "11452010;14562095;24374639;9169868", "class_list": "", "function": "Required for synthesis of pyridoxal-5-phosphate from vitamin B6 (By similarity). Important for bud site selection., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLM0", "ec_number_list": [ { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "5.4.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.11", "type": "external" }, { "id": "2.7.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.1", "type": "external" }, { "id": "4.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.24", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.1", "type": "external" }, { "id": "3.4.23.25", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.25", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "5.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.9", "type": "external" }, { "id": "5.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.3.-", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "3.5.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.6", "type": "external" }, { "id": "2.7.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.11", "type": "external" }, { "id": "2.7.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.2", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "3.4.25.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.25.1", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "2.3.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.16", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "1.11.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.24", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.4.1.186", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.186", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.4.2.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.7", "type": "external" }, { "id": "3.5.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.3", "type": "external" }, { "id": "5.4.2.7", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.7", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.4.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.1", "type": "external" }, { "id": "2.7.1.59", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.59", "type": "external" }, { "id": "3.2.1.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.14", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008478 pyridoxal kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005777 peroxisome;GO:0005829 cytosol", "go_biological_process": "GO:0009443 pyridoxal 5'-phosphate salvage;GO:0042823 pyridoxal phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P39988-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P39994-1", "uniprot_id": [ { "id": "PXP1_YEAST", "url": "https://www.uniprot.org/uniprot/P39994", "type": "external" } ], "mass": 61288.0, "length": 560, "protein_name": "2-hydroxyacyl-CoA lyase", "gene_name": "PXP1", "organism": "Yeast", "refseq_name": "putative indolepyruvate decarboxylase family protein", "refseq_ac": [ { "id": "NP_010895", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010895", "type": "external" } ], "gene_names_uniprotkb": "PXP1", "gene_names_refseq": "PXP1", "protein_names_uniprotkb": "2-hydroxyacyl-CoA lyase; 4.1.2.63; Peroxisomal protein 1", "protein_names_refseq": "putative indolepyruvate decarboxylase family protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YEL020C); (R-SCE-389599); (R-SCE-9033241)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "14562095;24374639;26928762;27392156;9169868", "class_list": "", "function": "Catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLM9", "ec_number_list": [ { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "1.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.2.4", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "1.3.1.124", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.124", "type": "external" }, { "id": "2.3.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.7", "type": "external" }, { "id": "4.1.2.63", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.63", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.8", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.1.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.56", "type": "external" }, { "id": "3.6.1.77", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.77", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0030976 thiamine pyrophosphate binding;GO:0016830 carbon-carbon lyase activity;GO:0106359 2-hydroxyacyl-CoA lyase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005777 peroxisome;GO:0005782 peroxisomal matrix", "go_biological_process": "GO:0001561 fatty acid alpha-oxidation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P39994-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40002-1", "uniprot_id": [ { "id": "MIT1_YEAST", "url": "https://www.uniprot.org/uniprot/P40002", "type": "external" } ], "mass": 72534.0, "length": 666, "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "organism": "Yeast", "refseq_name": "Mit1p", "refseq_ac": [ { "id": "NP_010909", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010909", "type": "external" } ], "gene_names_uniprotkb": "MIT1", "gene_names_refseq": "MIT1", "protein_names_uniprotkb": "Transcriptional regulator MIT1", "protein_names_refseq": "Mit1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YEL007W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562095;14562106;18407956;19779198;21126336;22095082;23749301;24374639;32597660;33229814;33491328;9169868", "class_list": "", "function": "Transcription factor that acts as a master regulator of a morphological transition, and more specifically pseudohyphal growth (PubMed:22095082). Appears to be as integral a part of the core filamentous growth network (PubMed:22095082). Binds to the promoters of 4 of the 5 known flocculin genes (FLO1, FLO9, FLO10, and FLO11 but not FLO5) (PubMed:22095082). Also regulates 21 genes encoding sequence-specific DNA-binding proteins, including PHD1, SOK2, MGA1, TEC1 and MIT1 itself (PubMed:22095082)., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 8, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 8, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 8, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D3DLP0", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P40002-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40004-1", "uniprot_id": [ { "id": "YEA4_YEAST", "url": "https://www.uniprot.org/uniprot/P40004", "type": "external" } ], "mass": 39266.0, "length": 342, "protein_name": "UDP-N-acetylglucosamine transporter YEA4", "gene_name": "YEA4", "organism": "Yeast", "refseq_name": "Yea4p", "refseq_ac": [ { "id": "NP_010912", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010912", "type": "external" } ], "gene_names_uniprotkb": "YEA4", "gene_names_refseq": "YEA4", "protein_names_uniprotkb": "UDP-N-acetylglucosamine transporter YEA4", "protein_names_refseq": "Yea4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YEL004W); (R-SCE-727802)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10788474;16847258;24374639;9169868", "class_list": "", "function": "Sugar transporter that specifically mediates the transport of UDP-N-acetylglucosamine (UDP-GlcNAc) and is required for cell wall chitin synthesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLP3", "ec_number_list": [], "go_molecular_function": "GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity;GO:0005464 UDP-xylose transmembrane transporter activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0055085 transmembrane transport;GO:0015786 UDP-glucose transmembrane transport;GO:1990569 UDP-N-acetylglucosamine transmembrane transport;GO:0006031 chitin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P40004-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40006-1", "uniprot_id": [ { "id": "IRC22_YEAST", "url": "https://www.uniprot.org/uniprot/P40006", "type": "external" } ], "mass": 24992.0, "length": 225, "protein_name": "Increased recombination centers protein 22", "gene_name": "IRC22", "organism": "Yeast", "refseq_name": "Irc22p", "refseq_ac": [ { "id": "NP_010915", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010915", "type": "external" } ], "gene_names_uniprotkb": "IRC22", "gene_names_refseq": "IRC22", "protein_names_uniprotkb": "Increased recombination centers protein 22", "protein_names_refseq": "Irc22p", "tax_id": 559292, "disease": "", "pathway": " (sce:YEL001C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "1293887;14562095;14562106;17322287;18085829;24374639;9169868", "class_list": "", "function": "Is probably involved in a pathway contributing to genomic integrity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLP6;Q05243", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P40006-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40007-1", "uniprot_id": [ { "id": "NOP16_YEAST", "url": "https://www.uniprot.org/uniprot/P40007", "type": "external" } ], "mass": 26901.0, "length": 231, "protein_name": "Nucleolar protein 16", "gene_name": "NOP16", "organism": "Yeast", "refseq_name": "Nop16p", "refseq_ac": [ { "id": "NP_010917", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010917", "type": "external" } ], "gene_names_uniprotkb": "NOP16", "gene_names_refseq": "NOP16", "protein_names_uniprotkb": "Nucleolar protein 16", "protein_names_refseq": "Nop16p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER002W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "11583614;14562095;14562106;15100437;15769876;17287358;17322287;18407956;20702584;23749301;24374639;30516470;32597660;33481703;33491328;9169868", "class_list": "", "function": "Involved in the biogenesis of the 60S ribosomal subunit., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLP8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor", "go_biological_process": "GO:0042273 ribosomal large subunit biogenesis;GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P40007-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40012-1", "uniprot_id": [ { "id": "PPOX_YEAST", "url": "https://www.uniprot.org/uniprot/P40012", "type": "external" } ], "mass": 59703.0, "length": 539, "protein_name": "Protoporphyrinogen oxidase", "gene_name": "HEM14", "organism": "Yeast", "refseq_name": "oxygen-dependent protoporphyrinogen oxidase", "refseq_ac": [ { "id": "NP_010930", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010930", "type": "external" } ], "gene_names_uniprotkb": "HEM14", "gene_names_refseq": "HEM14", "protein_names_uniprotkb": "Protoporphyrinogen oxidase; 1.3.3.4; PPO", "protein_names_refseq": "oxygen-dependent protoporphyrinogen oxidase", "tax_id": 559292, "disease": "porphyria (Disease Ontology:DOID:13268); variegate porphyria (Disease Ontology:DOID:4346)", "pathway": " (sce:YER014W); (R-SCE-189451)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "14562106;22814378;24374639;7798202;8621563;9169868", "class_list": "", "function": "Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLR1", "ec_number_list": [ { "id": "1.3.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.3.4", "type": "external" } ], "go_molecular_function": "GO:0004729 oxygen-dependent protoporphyrinogen oxidase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006783 heme biosynthetic process;GO:0006782 protoporphyrinogen IX biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P40012-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40017-1", "uniprot_id": [ { "id": "YAT2_YEAST", "url": "https://www.uniprot.org/uniprot/P40017", "type": "external" } ], "mass": 103334.0, "length": 923, "protein_name": "Carnitine O-acetyltransferase YAT2", "gene_name": "YAT2", "organism": "Yeast", "refseq_name": "carnitine O-acetyltransferase YAT2", "refseq_ac": [ { "id": "NP_010941", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010941", "type": "external" } ], "gene_names_uniprotkb": "YAT2", "gene_names_refseq": "YAT2", "protein_names_uniprotkb": "Carnitine O-acetyltransferase YAT2; 2.3.1.7", "protein_names_refseq": "carnitine O-acetyltransferase YAT2", "tax_id": 559292, "disease": "", "pathway": " (sce:YER024W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "11329169;14562095;14562106;17563356;18407956;18427809;19779198;22814378;23749301;24374639;33481703;33491328;9169868", "class_list": "", "function": "Carnitine O-acetyltransferase involved in the shutteling of acetyl-CoA in the cell., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 18, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLS3", "ec_number_list": [ { "id": "2.3.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.7", "type": "external" } ], "go_molecular_function": "GO:0004092 carnitine O-acetyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0006066 alcohol metabolic process;GO:0009437 carnitine metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P40017-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40019-1", "uniprot_id": [ { "id": "CHZ1_YEAST", "url": "https://www.uniprot.org/uniprot/P40019", "type": "external" } ], "mass": 17463.0, "length": 153, "protein_name": "Histone H2A.Z-specific chaperone CHZ1", "gene_name": "CHZ1", "organism": "Yeast", "refseq_name": "Chz1p", "refseq_ac": [ { "id": "NP_010947", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010947", "type": "external" } ], "gene_names_uniprotkb": "CHZ1", "gene_names_refseq": "CHZ1", "protein_names_uniprotkb": "Histone H2A.Z-specific chaperone CHZ1", "protein_names_refseq": "Chz1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER030W)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "12748633;14562095;14562106;15905473;17289584;18407956;19779198;21126336;21177495;22218487;22814378;23749301;24374639;24909858;30516470;33481703;33491328;9169868", "class_list": "", "function": "Forms a chaperone-bound H2A.Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A.Z histone replacement in chromatin., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLS9", "ec_number_list": [], "go_molecular_function": "GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006338 chromatin remodeling", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P40019-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40023-1", "uniprot_id": [ { "id": "EDC2_YEAST", "url": "https://www.uniprot.org/uniprot/P40023", "type": "external" } ], "mass": 16071.0, "length": 145, "protein_name": "Enhancer of mRNA-decapping protein 2", "gene_name": "EDC2", "organism": "Yeast", "refseq_name": "Edc2p", "refseq_ac": [ { "id": "NP_010952", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010952", "type": "external" } ], "gene_names_uniprotkb": "EDC2", "gene_names_refseq": "EDC2", "protein_names_uniprotkb": "Enhancer of mRNA-decapping protein 2", "protein_names_refseq": "Edc2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER035W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "11139489;12554866;12554867;14562095;14562106;17322287;23749301;24374639;32597660;33491328;9169868", "class_list": "", "function": "mRNA-binding protein which stimulates mRNA decapping by DCP1 and DCP2., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLT4", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0006397 mRNA processing;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0032056 positive regulation of translation in response to stress", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P40023-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40025-1", "uniprot_id": [ { "id": "PHM8_YEAST", "url": "https://www.uniprot.org/uniprot/P40025", "type": "external" } ], "mass": 37719.0, "length": 321, "protein_name": "Phosphate metabolism protein 8", "gene_name": "PHM8", "organism": "Yeast", "refseq_name": "bifunctional nucleotidase/lysophosphatidic acid phosphatase", "refseq_ac": [ { "id": "NP_010954", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010954", "type": "external" } ], "gene_names_uniprotkb": "PHM8", "gene_names_refseq": "PHM8", "protein_names_uniprotkb": "Phosphate metabolism protein 8", "protein_names_refseq": "bifunctional nucleotidase/lysophosphatidic acid phosphatase", "tax_id": 559292, "disease": "", "pathway": " (sce:YER037W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11102525;14562106;24374639;33481703;33491328;9169868", "class_list": "", "function": "May be involved in phosphate metabolism., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLT6", "ec_number_list": [], "go_molecular_function": "GO:0052642 lysophosphatidic acid phosphatase activity;GO:0008252 nucleotidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0070328 triglyceride homeostasis;GO:0016036 cellular response to phosphate starvation;GO:0006206 pyrimidine nucleobase metabolic process;GO:0009166 nucleotide catabolic process;GO:0090549 response to carbon starvation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P40025-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40026-1", "uniprot_id": [ { "id": "KRE29_YEAST", "url": "https://www.uniprot.org/uniprot/P40026", "type": "external" } ], "mass": 53772.0, "length": 464, "protein_name": "DNA repair protein KRE29", "gene_name": "KRE29", "organism": "Yeast", "refseq_name": "Smc5-Smc6 complex subunit KRE29", "refseq_ac": [ { "id": "NP_010955", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010955", "type": "external" } ], "gene_names_uniprotkb": "KRE29", "gene_names_refseq": "KRE29; NSE6", "protein_names_uniprotkb": "DNA repair protein KRE29; Killer toxin-resistance protein 29", "protein_names_refseq": "Smc5-Smc6 complex subunit KRE29", "tax_id": 559292, "disease": "", "pathway": " (sce:YER038C)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "14562095;14690591;15738391;17330950;18407956;19779198;19795423;19823750;20702584;21177495;23749301;24374639;32597660;33481703;33491328;9169868", "class_list": "", "function": "Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLT7", "ec_number_list": [], "go_molecular_function": "GO:0042030 ATPase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000781 chromosome, telomeric region;GO:0030915 Smc5-Smc6 complex", "go_biological_process": "GO:0032204 regulation of telomere maintenance;GO:0006281 DNA repair;GO:0000724 double-strand break repair via homologous recombination;GO:0140588 chromatin looping", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P40026-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40029-1", "uniprot_id": [ { "id": "MSRA_YEAST", "url": "https://www.uniprot.org/uniprot/P40029", "type": "external" } ], "mass": 21141.0, "length": 184, "protein_name": "Peptide methionine sulfoxide reductase", "gene_name": "MXR1", "organism": "Yeast", "refseq_name": "peptide-methionine-S-sulfoxide reductase", "refseq_ac": [ { "id": "NP_010960", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010960", "type": "external" } ], "gene_names_uniprotkb": "MXR1", "gene_names_refseq": "MXR1", "protein_names_uniprotkb": "Peptide methionine sulfoxide reductase; 1.8.4.11; Peptide Met(O) reductase; Peptide-methionine (S)-S-oxide reductase; Protein-methionine-S-oxide reductase", "protein_names_refseq": "peptide-methionine-S-sulfoxide reductase", "tax_id": 559292, "disease": "", "pathway": " (sce:YER042W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10473395;10799493;14562106;17322287;17563356;18407956;19779198;21126336;24374639;30516470;33481703;33491328;9169868", "class_list": "", "function": "Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. Also able to reduce dimethyl sulfoxide (DMSO) as well, with DMS as the product., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLU2", "ec_number_list": [ { "id": "1.8.4.11", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.4.11", "type": "external" } ], "go_molecular_function": "GO:0008113 peptide-methionine (S)-S-oxide reductase activity;GO:0033744 L-methionine:thioredoxin-disulfide S-oxidoreductase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0034599 cellular response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P40029-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40031-1", "uniprot_id": [ { "id": "SPO73_YEAST", "url": "https://www.uniprot.org/uniprot/P40031", "type": "external" } ], "mass": 16598.0, "length": 143, "protein_name": "Sporulation-specific protein 73", "gene_name": "SPO73", "organism": "Yeast", "refseq_name": "Spo73p", "refseq_ac": [ { "id": "NP_010965", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010965", "type": "external" } ], "gene_names_uniprotkb": "SPO73", "gene_names_refseq": "SPO73", "protein_names_uniprotkb": "Sporulation-specific protein 73", "protein_names_refseq": "Spo73p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER046W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "11470404;15590821;17322287;24374639;26605945;27303688;29897761;33481703;33491328;9169868", "class_list": "", "function": "Required for spore wall assembly and ascus formation (PubMed:11470404, PubMed:15590821). Involved in the formation and elongation of prospore membranes (PubMed:26605945, PubMed:27303688)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLU7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0005628 prospore membrane", "go_biological_process": "GO:0030437 ascospore formation;GO:0030476 ascospore wall assembly;GO:0032120 ascospore-type prospore membrane formation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P40031-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40033-1", "uniprot_id": [ { "id": "RSM18_YEAST", "url": "https://www.uniprot.org/uniprot/P40033", "type": "external" } ], "mass": 15835.0, "length": 138, "protein_name": "Small ribosomal subunit protein bS18m", "gene_name": "RSM18", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein bS18m RSM18", "refseq_ac": [ { "id": "NP_010970", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010970", "type": "external" } ], "gene_names_uniprotkb": "RSM18", "gene_names_refseq": "RSM18; bS18m", "protein_names_uniprotkb": "Small ribosomal subunit protein bS18m; 37S ribosomal protein RSM18, mitochondrial", "protein_names_refseq": "mitochondrial 37S ribosomal protein bS18m RSM18", "tax_id": 559292, "disease": "", "pathway": " (sce:YER050C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11278769;14562106;14576278;15905473;24374639;25609543;28154081;9169868", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLV2", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome;GO:0070181 small ribosomal subunit rRNA binding", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P40033-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40035-1", "uniprot_id": [ { "id": "PIC2_YEAST", "url": "https://www.uniprot.org/uniprot/P40035", "type": "external" } ], "mass": 33528.0, "length": 300, "protein_name": "Mitochondrial phosphate carrier protein 2", "gene_name": "PIC2", "organism": "Yeast", "refseq_name": "Cu/Pi carrier", "refseq_ac": [ { "id": "NP_010973", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010973", "type": "external" } ], "gene_names_uniprotkb": "PIC2", "gene_names_refseq": "PIC2", "protein_names_uniprotkb": "Mitochondrial phosphate carrier protein 2; PTP 2; Phosphate transport protein 2; Pi carrier isoform 2; mPic 2", "protein_names_refseq": "Cu/Pi carrier", "tax_id": 559292, "disease": "mitochondrial metabolism disease (Disease Ontology:DOID:700)", "pathway": " (sce:YER053C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11328608;14562106;14756774;22814378;24374639;9169868", "class_list": "", "function": "Transport of phosphate groups from the cytosol to the mitochondrial matrix., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLV5", "ec_number_list": [], "go_molecular_function": "GO:0005315 phosphate transmembrane transporter activity;GO:0005375 copper ion transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0035434 copper ion transmembrane transport;GO:0006878 intracellular copper ion homeostasis;GO:0035435 phosphate ion transmembrane transport;GO:1990547 mitochondrial phosphate ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P40035-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40037-1", "uniprot_id": [ { "id": "HMF1_YEAST", "url": "https://www.uniprot.org/uniprot/P40037", "type": "external" } ], "mass": 13906.0, "length": 129, "protein_name": "Protein HMF1", "gene_name": "HMF1", "organism": "Yeast", "refseq_name": "putative isoleucine biosynthesis protein HMF1", "refseq_ac": [ { "id": "NP_010978", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010978", "type": "external" } ], "gene_names_uniprotkb": "HMF1; HIG1", "gene_names_refseq": "HIG1; HMF1", "protein_names_uniprotkb": "Protein HMF1; High dosage growth inhibitor; Homologous mitochondrial matrix factor 1", "protein_names_refseq": "putative isoleucine biosynthesis protein HMF1", "tax_id": 559292, "disease": "", "pathway": " (sce:YER057C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "11003673;11442631;12112709;14562106;17322287;18407956;22106047;22984289;24374639;33481703;33491328;9169868", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLW1", "ec_number_list": [], "go_molecular_function": "GO:0019239 deaminase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005758 mitochondrial intermembrane space;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P40037-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40039-1", "uniprot_id": [ { "id": "FCY21_YEAST", "url": "https://www.uniprot.org/uniprot/P40039", "type": "external" } ], "mass": 58050.0, "length": 528, "protein_name": "Purine-cytosine permease FCY21", "gene_name": "FCY21", "organism": "Yeast", "refseq_name": "purine-cytosine permease", "refseq_ac": [ { "id": "NP_010981", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010981", "type": "external" } ], "gene_names_uniprotkb": "FCY21; FCYY", "gene_names_refseq": "FCY21", "protein_names_uniprotkb": "Purine-cytosine permease FCY21; Cytosine/purine transport protein FCY21; Fluorocytosine resistance protein 21; PCP FCY21", "protein_names_refseq": "purine-cytosine permease", "tax_id": 559292, "disease": "", "pathway": " (sce:YER060W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "16847258;19779198;19795423;19823750;23749301;24374639;32597660;33481703;33491328;9169868", "class_list": "", "function": "Probable purine-cytosine permease., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D3DLW4", "ec_number_list": [], "go_molecular_function": "GO:0015205 nucleobase transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0072530 purine-containing compound transmembrane transport;GO:0015856 cytosine transport", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P40039-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40040-1", "uniprot_id": [ { "id": "THO1_YEAST", "url": "https://www.uniprot.org/uniprot/P40040", "type": "external" } ], "mass": 24138.0, "length": 218, "protein_name": "Protein THO1", "gene_name": "THO1", "organism": "Yeast", "refseq_name": "Tho1p", "refseq_ac": [ { "id": "NP_010985", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010985", "type": "external" } ], "gene_names_uniprotkb": "THO1", "gene_names_refseq": "THO1", "protein_names_uniprotkb": "Protein THO1", "protein_names_refseq": "Tho1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER063W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "14562106;17322287;18407956;19779198;19795423;19823750;21177495;22814378;23749301;24374639;24909858;32597660;33481703;33491328;37578863;9169868;9707445", "class_list": "", "function": "Facilitates RNA binding of SUB2 and likely plays a role in mRNA export (PubMed:37578863). Suppressor of the transcriptional defect of HPR1 by overexpression., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLW8", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003723 RNA binding;GO:0003690 double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0016973 poly(A)+ mRNA export from nucleus;GO:0006368 transcription elongation by RNA polymerase II;GO:0022618 protein-RNA complex assembly", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P40040-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40041-1", "uniprot_id": [ { "id": "VHR2_YEAST", "url": "https://www.uniprot.org/uniprot/P40041", "type": "external" } ], "mass": 56638.0, "length": 505, "protein_name": "Transcription factor VHR2", "gene_name": "VHR2", "organism": "Yeast", "refseq_name": "Vhr2p", "refseq_ac": [ { "id": "NP_010986", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010986", "type": "external" } ], "gene_names_uniprotkb": "VHR2", "gene_names_refseq": "VHR2", "protein_names_uniprotkb": "Transcription factor VHR2; VHT1 regulator 2", "protein_names_refseq": "Vhr2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER064C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11342098;14562095;14562106;22189060;23749301;24374639;33491328;9169868", "class_list": "", "function": "Transcription factor that regulates ERG9, but seems to have a more global function in transcription., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D3DLW9", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P40041-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40043-1", "uniprot_id": [ { "id": "RGI1_YEAST", "url": "https://www.uniprot.org/uniprot/P40043", "type": "external" } ], "mass": 18989.0, "length": 161, "protein_name": "Respiratory growth induced protein 1", "gene_name": "RGI1", "organism": "Yeast", "refseq_name": "Rgi1p", "refseq_ac": [ { "id": "NP_010990", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010990", "type": "external" } ], "gene_names_uniprotkb": "RGI1", "gene_names_refseq": "RGI1", "protein_names_uniprotkb": "Respiratory growth induced protein 1", "protein_names_refseq": "Rgi1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER067W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10770760;12872131;14562106;15870279;17322287;18756096;20567505;24374639;33491328;9169868", "class_list": "", "function": "Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLX2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0006112 energy reserve metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P40043-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40045-1", "uniprot_id": [ { "id": "TDA2_YEAST", "url": "https://www.uniprot.org/uniprot/P40045", "type": "external" } ], "mass": 14498.0, "length": 126, "protein_name": "Topoisomerase I damage affected protein 2", "gene_name": "TDA2", "organism": "Yeast", "refseq_name": "Tda2p", "refseq_ac": [ { "id": "NP_010994", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010994", "type": "external" } ], "gene_names_uniprotkb": "TDA2", "gene_names_refseq": "TDA2", "protein_names_uniprotkb": "Topoisomerase I damage affected protein 2", "protein_names_refseq": "Tda2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER071C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;17322287;19053807;21173034;22814378;24374639;33491328;9169868", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLX6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030479 actin cortical patch;GO:0110131 Aim21-Tda2 complex;GO:0043332 mating projection tip", "go_biological_process": "GO:0030837 negative regulation of actin filament polymerization;GO:2000813 negative regulation of barbed-end actin filament capping", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P40045-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40050-1", "uniprot_id": [ { "id": "MRX1_YEAST", "url": "https://www.uniprot.org/uniprot/P40050", "type": "external" } ], "mass": 79548.0, "length": 688, "protein_name": "MIOREX complex component 1", "gene_name": "MRX1", "organism": "Yeast", "refseq_name": "Mrx1p", "refseq_ac": [ { "id": "NP_011000", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011000", "type": "external" } ], "gene_names_uniprotkb": "MRX1", "gene_names_refseq": "MRX1", "protein_names_uniprotkb": "MIOREX complex component 1; Mitochondrial organization of gene expression protein 1", "protein_names_refseq": "Mrx1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER077C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;14562106;24374639;25683707;33491328;9169868", "class_list": "", "function": "Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLY3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P40050-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40051-1", "uniprot_id": [ { "id": "ICP55_YEAST", "url": "https://www.uniprot.org/uniprot/P40051", "type": "external" } ], "mass": 57990.0, "length": 511, "protein_name": "Intermediate cleaving peptidase 55", "gene_name": "ICP55", "organism": "Yeast", "refseq_name": "aminopeptidase", "refseq_ac": [ { "id": "NP_011001", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011001", "type": "external" } ], "gene_names_uniprotkb": "ICP55", "gene_names_refseq": "ICP55", "protein_names_uniprotkb": "Intermediate cleaving peptidase 55; 3.4.11.26; Intermediate cleaving peptidase of 55 kDa", "protein_names_refseq": "aminopeptidase", "tax_id": 559292, "disease": "nephronophthisis-like nephropathy 1 (Disease Ontology:DOID:0111117)", "pathway": " (sce:YER078C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;16823961;19720832;19837041;24374639;9169868", "class_list": "", "function": "Aminopeptidase which cleaves preprotein intermediates that carry destabilizing N-ter amino acid residues after the mitochondrial processing peptidase (MPP) cleavage site and is thus critical for stabilization of the mitochondrial proteome. Cleaves NFS1 (PubMed:19720832)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLY4", "ec_number_list": [], "go_molecular_function": "GO:0030145 manganese ion binding;GO:0004177 aminopeptidase activity;GO:0070006 metalloaminopeptidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0016485 protein processing;GO:0050821 protein stabilization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P40051-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40063-1", "uniprot_id": [ { "id": "RT105_YEAST", "url": "https://www.uniprot.org/uniprot/P40063", "type": "external" } ], "mass": 24413.0, "length": 208, "protein_name": "Regulator of Ty1 transposition protein 105", "gene_name": "RTT105", "organism": "Yeast", "refseq_name": "Rtt105p", "refseq_ac": [ { "id": "NP_011030", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011030", "type": "external" } ], "gene_names_uniprotkb": "RTT105", "gene_names_refseq": "RTT105", "protein_names_uniprotkb": "Regulator of Ty1 transposition protein 105", "protein_names_refseq": "Rtt105p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER104W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "11779788;14562095;14562106;17322287;18407956;19779198;21177495;23749301;24374639;32597660;33481703;33491328;9169868", "class_list": "", "function": "Involved in regulation of Ty1 transposition. Inhibits Ty1 transposition at a post-transcriptional and pre-integrational stage of the Ty1 retrotransposition cycle., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM11", "ec_number_list": [], "go_molecular_function": "GO:0060590 ATPase regulator activity;GO:0140597 protein carrier chaperone", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000723 telomere maintenance;GO:0000724 double-strand break repair via homologous recombination;GO:0032196 transposition;GO:0000727 double-strand break repair via break-induced replication;GO:0031507 heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P40063-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40071-1", "uniprot_id": [ { "id": "TMN3_YEAST", "url": "https://www.uniprot.org/uniprot/P40071", "type": "external" } ], "mass": 81546.0, "length": 706, "protein_name": "Transmembrane 9 superfamily member 3", "gene_name": "TMN3", "organism": "Yeast", "refseq_name": "Tmn3p", "refseq_ac": [ { "id": "NP_011038", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011038", "type": "external" } ], "gene_names_uniprotkb": "TMN3", "gene_names_refseq": "TMN3", "protein_names_uniprotkb": "Transmembrane 9 superfamily member 3", "protein_names_refseq": "Tmn3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER113C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;16847258;18178563;20681974;24374639;33491328;9169868", "class_list": "", "function": "With EMP70 and TMN2, plays a critical role in the late stages of a nutrient-controlled pathway notably regulating FLO11 gene expression. Acts downstream of RAS2 and TOR. Essential for cell adhesion and filamentous growth. May play a role as effector of cellular copper homeostasis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM19", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0016020 membrane", "go_biological_process": "GO:0007034 vacuolar transport;GO:0006811 monoatomic ion transport;GO:0006878 intracellular copper ion homeostasis;GO:0072657 protein localization to membrane;GO:0001403 invasive growth in response to glucose limitation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P40071-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40074-1", "uniprot_id": [ { "id": "AVT6_YEAST", "url": "https://www.uniprot.org/uniprot/P40074", "type": "external" } ], "mass": 48840.0, "length": 448, "protein_name": "Vacuolar amino acid transporter 6", "gene_name": "AVT6", "organism": "Yeast", "refseq_name": "aspartate/glutamate transporter", "refseq_ac": [ { "id": "NP_011044", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011044", "type": "external" } ], "gene_names_uniprotkb": "AVT6", "gene_names_refseq": "AVT6", "protein_names_uniprotkb": "Vacuolar amino acid transporter 6", "protein_names_refseq": "aspartate/glutamate transporter", "tax_id": 559292, "disease": "foveal hypoplasia 2 (Disease Ontology:DOID:0070531)", "pathway": " (sce:YER119C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "11274162;16847258;18407956;19779198;22218487;24374639;33481703;33491328;7668045;9169868", "class_list": "", "function": "Involved in amino acid efflux from the vacuole to the cytoplasm. Capable of transporting aspartate and glutamate. Requires ATP for function., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM25", "ec_number_list": [], "go_molecular_function": "GO:0015194 L-serine transmembrane transporter activity;GO:0015189 L-lysine transmembrane transporter activity;GO:0005290 L-histidine transmembrane transporter activity;GO:0005302 L-tyrosine transmembrane transporter activity;GO:0005313 L-glutamate transmembrane transporter activity", "go_cellular_component": "GO:0000329 fungal-type vacuole membrane;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0055085 transmembrane transport;GO:0003333 amino acid transmembrane transport;GO:0032974 amino acid transmembrane export from vacuole", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P40074-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40080-1", "uniprot_id": [ { "id": "VFA1_YEAST", "url": "https://www.uniprot.org/uniprot/P40080", "type": "external" } ], "mass": 23489.0, "length": 203, "protein_name": "VPS4-associated protein 1", "gene_name": "VFA1", "organism": "Yeast", "refseq_name": "Vfa1p", "refseq_ac": [ { "id": "NP_011054", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011054", "type": "external" } ], "gene_names_uniprotkb": "VFA1; SYGP-ORF44", "gene_names_refseq": "VFA1", "protein_names_uniprotkb": "VPS4-associated protein 1", "protein_names_refseq": "Vfa1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER128W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;21777356;22814378;23749301;24374639;33481703;33491328;9169868", "class_list": "", "function": "VPS4-associated protein involved in trafficking to the vacuole., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM34", "ec_number_list": [], "go_molecular_function": "GO:0001671 ATPase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome", "go_biological_process": "GO:0007034 vacuolar transport;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P40080-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40081-1", "uniprot_id": [ { "id": "MGDP1_YEAST", "url": "https://www.uniprot.org/uniprot/P40081", "type": "external" } ], "mass": 20441.0, "length": 178, "protein_name": "Putative magnesium-dependent phosphatase YER134C", "gene_name": "", "organism": "Yeast", "refseq_name": "Mg-dependent acid phosphatase", "refseq_ac": [ { "id": "NP_011060", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011060", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Putative magnesium-dependent phosphatase YER134C; 3.1.3.48", "protein_names_refseq": "Mg-dependent acid phosphatase", "tax_id": 559292, "disease": "", "pathway": " (sce:YER134C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;17322287;18407956;19779198;24374639;9169868", "class_list": "", "function": "Magnesium-dependent phosphatase which may act as a tyrosine phosphatase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM40", "ec_number_list": [ { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003993 acid phosphatase activity;GO:0030946 protein tyrosine phosphatase activity, metal-dependent", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P40081-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40085-1", "uniprot_id": [ { "id": "TAPT1_YEAST", "url": "https://www.uniprot.org/uniprot/P40085", "type": "external" } ], "mass": 64794.0, "length": 556, "protein_name": "Endoplasmic reticulum membrane protein 65", "gene_name": "EMP65", "organism": "Yeast", "refseq_name": "Emp65p", "refseq_ac": [ { "id": "NP_011067", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011067", "type": "external" } ], "gene_names_uniprotkb": "EMP65", "gene_names_refseq": "EMP65", "protein_names_uniprotkb": "Endoplasmic reticulum membrane protein 65; 65 kDa endoplasmic reticulum membrane protein", "protein_names_refseq": "Emp65p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER140W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "14576278;16847258;17330950;18407956;19325107;19779198;23275891;23749301;24374639;32597660;33481703;33491328;9169868", "class_list": "", "function": "May be involved in membrane protein folding., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D3DM47", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0034975 protein folding in endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P40085-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40092-1", "uniprot_id": [ { "id": "SPI1_YEAST", "url": "https://www.uniprot.org/uniprot/P40092", "type": "external" } ], "mass": 14996.0, "length": 148, "protein_name": "Uncharacterized cell wall protein SPI1", "gene_name": "SPI1", "organism": "Yeast", "refseq_name": "Spi1p", "refseq_ac": [ { "id": "NP_011077", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011077", "type": "external" } ], "gene_names_uniprotkb": "SPI1", "gene_names_refseq": "SPI1", "protein_names_uniprotkb": "Uncharacterized cell wall protein SPI1; Stationary phase-induced protein 1", "protein_names_refseq": "Spi1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER150W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10383953;10641036;11136466;16980434;17322287;24374639;9169868;9613572", "class_list": "", "function": "Cell wall protein that plays a role in adaptation and resistance to cell wall stress., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D3DM57", "ec_number_list": [], "go_molecular_function": "GO:0005199 structural constituent of cell wall", "go_cellular_component": "GO:0071944 cell periphery;GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0010447 response to acidic pH;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P40092-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40099-1", "uniprot_id": [ { "id": "FTHC_YEAST", "url": "https://www.uniprot.org/uniprot/P40099", "type": "external" } ], "mass": 24059.0, "length": 211, "protein_name": "5-formyltetrahydrofolate cyclo-ligase", "gene_name": "FAU1", "organism": "Yeast", "refseq_name": "5-formyltetrahydrofolate cyclo-ligase", "refseq_ac": [ { "id": "NP_011110", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011110", "type": "external" } ], "gene_names_uniprotkb": "FAU1", "gene_names_refseq": "FAU1", "protein_names_uniprotkb": "5-formyltetrahydrofolate cyclo-ligase; 5,10-methenyl-tetrahydrofolate synthetase; 6.3.3.2; MTHFS; Methenyl-THF synthetase", "protein_names_refseq": "5-formyltetrahydrofolate cyclo-ligase", "tax_id": 559292, "disease": "", "pathway": " (sce:YER183C); (R-SCE-196757)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "11923304;14562106;14576278;19756047;24374639;9169868", "class_list": "", "function": "Only enzyme known to utilize 5-formyltetrahydrofolate (folinic acid) as substrate. Contributes to tetrahydrofolate metabolism in an alternative way of folate biosynthesis. May regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM92", "ec_number_list": [ { "id": "6.3.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.3.2", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0035999 tetrahydrofolate interconversion;GO:0009396 folic acid-containing compound biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P40099-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40100-1", "uniprot_id": [ { "id": "PUG1_YEAST", "url": "https://www.uniprot.org/uniprot/P40100", "type": "external" } ], "mass": 33733.0, "length": 303, "protein_name": "Protoporphyrin uptake protein 1", "gene_name": "PUG1", "organism": "Yeast", "refseq_name": "Pug1p", "refseq_ac": [ { "id": "NP_011112", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011112", "type": "external" } ], "gene_names_uniprotkb": "PUG1", "gene_names_refseq": "PUG1", "protein_names_uniprotkb": "Protoporphyrin uptake protein 1", "protein_names_refseq": "Pug1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER185W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12524434;18326586;19756047;19779198;24374639;33481703;9169868", "class_list": "", "function": "Involved in inducible protoporphyrin IX influx and heme efflux., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM94", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0035351 heme transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P40100-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40105-1", "uniprot_id": [ { "id": "YRF12_YEAST", "url": "https://www.uniprot.org/uniprot/P40105", "type": "external" } ], "mass": 190503.0, "length": 1681, "protein_name": "Y' element ATP-dependent helicase protein 1 copy 2", "gene_name": "YRF1-2", "organism": "Yeast", "refseq_name": "Y' element ATP-dependent helicase protein 1 copy 2", "refseq_ac": [ { "id": "NP_011117", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011117", "type": "external" } ], "gene_names_uniprotkb": "YRF1-2", "gene_names_refseq": "YRF1-2; YRF1", "protein_names_uniprotkb": "Y' element ATP-dependent helicase protein 1 copy 2; 5.6.2.-", "protein_names_refseq": "Y' element ATP-dependent helicase protein 1 copy 2", "tax_id": 559292, "disease": "", "pathway": " (sce:YER190W)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "24374639;9169868;9837911", "class_list": "", "function": "Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM99", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003676 nucleic acid binding;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000722 telomere maintenance via recombination", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P40105-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40151-1", "uniprot_id": [ { "id": "WRIP1_YEAST", "url": "https://www.uniprot.org/uniprot/P40151", "type": "external" } ], "mass": 66544.0, "length": 587, "protein_name": "DNA-dependent ATPase MGS1", "gene_name": "MGS1", "organism": "Yeast", "refseq_name": "ssDNA-dependent ATPase MGS1", "refseq_ac": [ { "id": "NP_014181", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014181", "type": "external" } ], "gene_names_uniprotkb": "MGS1; N1302", "gene_names_refseq": "MGS1", "protein_names_uniprotkb": "DNA-dependent ATPase MGS1; Maintenance of genome stability protein 1", "protein_names_refseq": "ssDNA-dependent ATPase MGS1", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL218W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "11301316;11459965;12436259;14562106;17322287;24374639;33229814;7762305;9169873", "class_list": "", "function": "Involved in the maintenance of proper DNA topology and chromosome integrity via annealing of single-stranded DNA breaks. Modulates DNA polymerase delta during replication or replication-associated repair. May function as a modulator for SGS1 when DNA is damaged., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 9, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 9, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 9, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D6W0X2", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008047 enzyme activator activity;GO:0008270 zinc ion binding;GO:0016887 ATP hydrolysis activity;GO:0051880 G-quadruplex DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000731 DNA synthesis involved in DNA repair;GO:0006261 DNA-templated DNA replication;GO:0051276 chromosome organization;GO:0006282 regulation of DNA repair;GO:0033567 DNA replication, Okazaki fragment processing", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P40151-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40154-1", "uniprot_id": [ { "id": "IES2_YEAST", "url": "https://www.uniprot.org/uniprot/P40154", "type": "external" } ], "mass": 36154.0, "length": 320, "protein_name": "Ino eighty subunit 2", "gene_name": "IES2", "organism": "Yeast", "refseq_name": "Ies2p", "refseq_ac": [ { "id": "NP_014184", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014184", "type": "external" } ], "gene_names_uniprotkb": "IES2; N1315", "gene_names_refseq": "IES2", "protein_names_uniprotkb": "Ino eighty subunit 2", "protein_names_refseq": "Ies2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL215W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "12887900;14562095;14562106;17287358;17563356;18407956;19779198;21126336;22218487;24374639;33481703;33491328;7762305;9169873", "class_list": "", "function": "Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0X5", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0031011 Ino80 complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P40154-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40156-1", "uniprot_id": [ { "id": "RRG9_YEAST", "url": "https://www.uniprot.org/uniprot/P40156", "type": "external" } ], "mass": 25274.0, "length": 214, "protein_name": "Required for respiratory growth protein 9, mitochondrial", "gene_name": "RRG9", "organism": "Yeast", "refseq_name": "mitochondrial ribosome assembly protein RRG9", "refseq_ac": [ { "id": "NP_014186", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014186", "type": "external" } ], "gene_names_uniprotkb": "RRG9; N1323", "gene_names_refseq": "RRG9", "protein_names_uniprotkb": "Required for respiratory growth protein 9, mitochondrial", "protein_names_refseq": "mitochondrial ribosome assembly protein RRG9", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL213C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;16823961;19751518;24374639;7762305;9169873", "class_list": "", "function": "Required for respiratory activity and maintenance and expression of the mitochondrial genome., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0X7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0007005 mitochondrion organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P40156-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40165-1", "uniprot_id": [ { "id": "NNRE_YEAST", "url": "https://www.uniprot.org/uniprot/P40165", "type": "external" } ], "mass": 27521.0, "length": 246, "protein_name": "NAD(P)H-hydrate epimerase", "gene_name": "NNR1", "organism": "Yeast", "refseq_name": "NADHX epimerase", "refseq_ac": [ { "id": "NP_014199", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014199", "type": "external" } ], "gene_names_uniprotkb": "NNR1; N1370", "gene_names_refseq": "NNR1", "protein_names_uniprotkb": "NAD(P)H-hydrate epimerase; 5.1.99.6; NAD(P)HX epimerase; Nicotinamide nucleotide repair protein 1", "protein_names_refseq": "NADHX epimerase", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL200C); (R-SCE-196807)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "14562095;14562106;14576278;17322287;21994945;24374639;7725799;9169873", "class_list": "", "function": "Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX., [UniProtKB, HAMAP, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0Y8", "ec_number_list": [ { "id": "5.1.99.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.99.6", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000166 nucleotide binding;GO:0052856 NAD(P)HX epimerase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0046496 nicotinamide nucleotide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P40165-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40169-1", "uniprot_id": [ { "id": "YNT4_YEAST", "url": "https://www.uniprot.org/uniprot/P40169", "type": "external" } ], "mass": 34081.0, "length": 301, "protein_name": "Uncharacterized plasma membrane protein YNL194C", "gene_name": "N1394", "organism": "Yeast", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_014205", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014205", "type": "external" } ], "gene_names_uniprotkb": "N1394", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized plasma membrane protein YNL194C", "protein_names_refseq": "uncharacterized protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL194C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11784867;14562095;16847258;24374639;33491328;7725799;9169873", "class_list": "", "function": "Involved in sporulation and affects the sphingolipid composition of the plasma membrane., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0Z3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0045121 membrane raft", "go_biological_process": "GO:0006897 endocytosis;GO:0030866 cortical actin cytoskeleton organization;GO:0032185 septin cytoskeleton organization;GO:0030437 ascospore formation;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P40169-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40185-1", "uniprot_id": [ { "id": "MMF1_YEAST", "url": "https://www.uniprot.org/uniprot/P40185", "type": "external" } ], "mass": 15908.0, "length": 145, "protein_name": "Protein MMF1, mitochondrial", "gene_name": "MMF1", "organism": "Yeast", "refseq_name": "isoleucine biosynthesis protein MMF1", "refseq_ac": [ { "id": "NP_012213", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012213", "type": "external" } ], "gene_names_uniprotkb": "MMF1; IBM1", "gene_names_refseq": "IBM1; MMF1", "protein_names_uniprotkb": "Protein MMF1, mitochondrial; Isoleucine biosynthesis and maintenance of intact mitochondria 1; Maintenance of mitochondrial function 1", "protein_names_refseq": "isoleucine biosynthesis protein MMF1", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL051C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "11003673;11442631;14562106;17322287;18407956;21126336;24374639;33481703;33491328;9169870", "class_list": "", "function": "Plays a role in the maintenance of mitochondrial DNA., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVN0", "ec_number_list": [], "go_molecular_function": "GO:0019239 deaminase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0005829 cytosol", "go_biological_process": "GO:0032543 mitochondrial translation;GO:0009097 isoleucine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P40185-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40187-1", "uniprot_id": [ { "id": "PIG2_YEAST", "url": "https://www.uniprot.org/uniprot/P40187", "type": "external" } ], "mass": 61938.0, "length": 538, "protein_name": "GSY2-interacting protein PIG2", "gene_name": "PIG2", "organism": "Yeast", "refseq_name": "putative protein phosphatase regulator PIG2", "refseq_ac": [ { "id": "NP_012219", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012219", "type": "external" } ], "gene_names_uniprotkb": "PIG2", "gene_names_refseq": "PIG2", "protein_names_uniprotkb": "GSY2-interacting protein PIG2", "protein_names_refseq": "putative protein phosphatase regulator PIG2", "tax_id": 559292, "disease": "alcohol use disorder (Disease Ontology:DOID:1574); type 2 diabetes mellitus (Disease Ontology:DOID:9352); hypoglycemia (Disease Ontology:DOID:9993)", "pathway": " (sce:YIL045W); (R-SCE-3322077)", "pathway_count": 2, "publication_count": 18, "publication_id_list": "14562106;17287358;17322287;17330950;18407956;19779198;19795423;19823750;20489023;20702584;21177495;23749301;24374639;32597660;33481703;33491328;9046081;9169870", "class_list": "", "function": "Interacts with glycogen synthase 2 (GSY2); possibly also interacts with phosphatase 1 (GLC7)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVN7;E9P960", "ec_number_list": [], "go_molecular_function": "GO:0019888 protein phosphatase regulator activity;GO:0008157 protein phosphatase 1 binding;GO:2001069 glycogen binding", "go_cellular_component": "GO:0000164 protein phosphatase type 1 complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0005979 regulation of glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P40187-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40188-1", "uniprot_id": [ { "id": "RGI2_YEAST", "url": "https://www.uniprot.org/uniprot/P40188", "type": "external" } ], "mass": 19229.0, "length": 164, "protein_name": "Respiratory growth induced protein 2", "gene_name": "RGI2", "organism": "Yeast", "refseq_name": "Rgi2p", "refseq_ac": [ { "id": "NP_012207", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012207", "type": "external" } ], "gene_names_uniprotkb": "RGI2", "gene_names_refseq": "RGI2", "protein_names_uniprotkb": "Respiratory growth induced protein 2", "protein_names_refseq": "Rgi2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL057C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12414795;14562095;14562106;16969341;17322287;17563356;20567505;24374639;9169870", "class_list": "", "function": "Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVM5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006112 energy reserve metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P40188-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40207-1", "uniprot_id": [ { "id": "ERG29_YEAST", "url": "https://www.uniprot.org/uniprot/P40207", "type": "external" } ], "mass": 27921.0, "length": 237, "protein_name": "Ergosterol biosynthesis protein 29", "gene_name": "ERG29", "organism": "Yeast", "refseq_name": "Erg29p", "refseq_ac": [ { "id": "NP_013853", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013853", "type": "external" } ], "gene_names_uniprotkb": "ERG29; YM9375.03", "gene_names_refseq": "ERG29", "protein_names_uniprotkb": "Ergosterol biosynthesis protein 29", "protein_names_refseq": "Erg29p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR134W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562095;14562106;16135527;16630279;17322287;23892078;24374639;29773647;32679672;33481703;9169872;9180083", "class_list": "", "function": "Part of the third module of ergosterol biosynthesis pathway that includes the late steps of the pathway (PubMed:23892078). ERG29 regulates the activity of the iron-containing C4-methylsterol oxidase ERG25 (PubMed:23892078). The third module or late pathway involves the ergosterol synthesis itself through consecutive reactions that mainly occur in the endoplasmic reticulum (ER) membrane. Firstly, the squalene synthase ERG9 catalyzes the condensation of 2 farnesyl pyrophosphate moieties to form squalene, which is the precursor of all steroids. Squalene synthase is crucial for balancing the incorporation of farnesyl diphosphate (FPP) into sterol and nonsterol isoprene synthesis. Secondly, the squalene epoxidase ERG1 catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, which is considered to be a rate-limiting enzyme in steroid biosynthesis. Then, the lanosterol synthase ERG7 catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol core. In the next steps, lanosterol is transformed to zymosterol through a complex process involving various demethylation, reduction and desaturation reactions. The lanosterol 14-alpha-demethylase ERG11 (also known as CYP51) catalyzes C14-demethylation of lanosterol to produce 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol, which is critical for ergosterol biosynthesis. The C-14 reductase ERG24 reduces the C14=C15 double bond of 4,4-dimethyl-cholesta-8,14,24-trienol to produce 4,4-dimethyl-cholesta-8,24-dienol. 4,4-dimethyl-cholesta-8,24-dienol is substrate of the C-4 demethylation complex ERG25-ERG26-ERG27 in which ERG25 catalyzes the three-step monooxygenation required for the demethylation of 4,4-dimethyl and 4alpha-methylsterols, ERG26 catalyzes the oxidative decarboxylation that results in a reduction of the 3-beta-hydroxy group at the C-3 carbon to an oxo group, and ERG27 is responsible for the reduction of the keto group on the C-3. ERG28 has a role as a scaffold to help anchor ERG25, ERG26 and ERG27 to the endoplasmic reticulum and ERG29 regulates the activity of the iron-containing C4-methylsterol oxidase ERG25. Then, the sterol 24-C-methyltransferase ERG6 catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. The C-8 sterol isomerase ERG2 catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols and thus converts fecosterol to episterol. The sterol-C5-desaturase ERG3 then catalyzes the introduction of a C-5 double bond in the B ring to produce 5-dehydroepisterol. The C-22 sterol desaturase ERG5 further converts 5-dehydroepisterol into ergosta-5,7,22,24(28)-tetraen-3beta-ol by forming the C-22(23) double bond in the sterol side chain. Finally, ergosta-5,7,22,24(28)-tetraen-3beta-ol is substrate of the C-24(28) sterol reductase ERG4 to produce ergosterol (PubMed:32679672)., [UniProtKB, PubMed, PubMed]; Plays a role in maintaining mitochondrial and plasma membrane integrity and consequently impacting the iron homeostasis, respiratory metabolism and antioxidant response (PubMed:16135527, PubMed:16630279, PubMed:23892078, PubMed:29773647, PubMed:9180083)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZV7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006696 ergosterol biosynthetic process;GO:0006879 intracellular iron ion homeostasis;GO:0007005 mitochondrion organization", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P40207-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40210-1", "uniprot_id": [ { "id": "SIP5_YEAST", "url": "https://www.uniprot.org/uniprot/P40210", "type": "external" } ], "mass": 55859.0, "length": 489, "protein_name": "Protein SIP5", "gene_name": "SIP5", "organism": "Yeast", "refseq_name": "Sip5p", "refseq_ac": [ { "id": "NP_013860", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013860", "type": "external" } ], "gene_names_uniprotkb": "SIP5; YM9375.09", "gene_names_refseq": "SIP5", "protein_names_uniprotkb": "Protein SIP5; SNF1-interacting protein 5", "protein_names_refseq": "Sip5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR140W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "10628972;14562095;14562106;16170412;17330950;17563356;18086883;18407956;19779198;19795423;19823750;21177495;23749301;24374639;30516470;32597660;33481703;33491328;9169872", "class_list": "", "function": "May negatively regulate the SNF1 kinase by promoting the interaction of the REG1/GLC7 phosphatase complex with the kinase. Deletion of SIP5 promotes resistance to artemisinin, which is probably an indirect effect of an action on the electron transport chain., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 21, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VZW3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0042149 cellular response to glucose starvation", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P40210-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40212-1", "uniprot_id": [ { "id": "RL13B_YEAST", "url": "https://www.uniprot.org/uniprot/P40212", "type": "external" } ], "mass": 22525.0, "length": 199, "protein_name": "Large ribosomal subunit protein eL13B", "gene_name": "RPL13B", "organism": "Yeast", "refseq_name": "60S ribosomal protein eL13 RPL13B", "refseq_ac": [ { "id": "NP_013862", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013862", "type": "external" } ], "gene_names_uniprotkb": "RPL13B; RPL13; YM9375.11C", "gene_names_refseq": "RPL13B", "protein_names_uniprotkb": "Large ribosomal subunit protein eL13B; 60S ribosomal protein L13-B", "protein_names_refseq": "60S ribosomal protein eL13 RPL13B", "tax_id": 559292, "disease": "spondyloepimetaphyseal dysplasia (Disease Ontology:DOID:0080027); congenital heart disease (Disease Ontology:DOID:1682)", "pathway": " (sce:YMR142C); (R-SCE-156827); (R-SCE-1799339); (R-SCE-72689); (R-SCE-72706); (R-SCE-975956); (R-SCE-975957); (R-SCE-9954709); (R-SCE-9954714)", "pathway_count": 9, "publication_count": 14, "publication_id_list": "14562095;14562106;15665377;17287358;19779198;22096102;22218487;23749301;24374639;24524803;32597660;33491328;9169872;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZW4", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0016236 macroautophagy;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P40212-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40214-1", "uniprot_id": [ { "id": "FDO1_YEAST", "url": "https://www.uniprot.org/uniprot/P40214", "type": "external" } ], "mass": 38570.0, "length": 342, "protein_name": "Protein FDO1", "gene_name": "FDO1", "organism": "Yeast", "refseq_name": "Fdo1p", "refseq_ac": [ { "id": "NP_013864", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013864", "type": "external" } ], "gene_names_uniprotkb": "FDO1; YM9375.13", "gene_names_refseq": "FDO1", "protein_names_uniprotkb": "Protein FDO1; FKH1-interacting protein involved in donor preference", "protein_names_refseq": "Fdo1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR144W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562106;17563356;18407956;19795423;19823750;23749301;24374639;27257873;33481703;33491328;9169872", "class_list": "", "function": "In concert with FKH1, plays a role in directionality of mating type switching by controlling which donor mating-type locus is inserted into MAT locus during mating type switching., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 20, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZW6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0007535 donor selection", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P40214-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40219-1", "uniprot_id": [ { "id": "LDO16_YEAST", "url": "https://www.uniprot.org/uniprot/P40219", "type": "external" } ], "mass": 16384.0, "length": 148, "protein_name": "Lipid droplet organization protein LDO16", "gene_name": "LDO16", "organism": "Yeast", "refseq_name": "Ldo16p", "refseq_ac": [ { "id": "NP_013868", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013868", "type": "external" } ], "gene_names_uniprotkb": "LDO16; OSW5; YM9375.18", "gene_names_refseq": "LDO16; OSW5", "protein_names_uniprotkb": "Lipid droplet organization protein LDO16; Lipid droplet organization 16 KDa protein; Outer spore wall protein 5", "protein_names_refseq": "Ldo16p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR148W)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "14562095;14562106;16847258;17322287;17563356;18407956;19208812;19779198;19779569;21748599;21820081;22218487;23749301;24374639;26572621;29187527;29187528;33481703;33491328;9169872", "class_list": "", "function": "Involved in lipid droplet (LD) organization. Functions primarily upon nutrient depletion, facilitating LD consumption by lipophagy (PubMed:29187528). Required for correct LD distribution during entry into stationary phase, where LDs accumulate at nucleus-vacuole junction (NVJ) contact sites (PubMed:29187527). Involved in membrane interaction in a manner similar to those of SNARE proteins, binding to partners present in mitochondria or peroxisomes. Its partner on the mitochondrion side might be TOM22, a mitochondrial outer membrane protein, linking lipid droplets and mitochondria by protein-protein interaction (Probable). Involved in spore wall assembly (PubMed:19779569)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZX0", "ec_number_list": [], "go_molecular_function": "GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005811 lipid droplet;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0034389 lipid droplet organization;GO:0061724 lipophagy;GO:0030476 ascospore wall assembly", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P40219-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40260-1", "uniprot_id": [ { "id": "MEP1_YEAST", "url": "https://www.uniprot.org/uniprot/P40260", "type": "external" } ], "mass": 54202.0, "length": 492, "protein_name": "Ammonium transporter MEP1", "gene_name": "MEP1", "organism": "Yeast", "refseq_name": "ammonium permease MEP1", "refseq_ac": [ { "id": "NP_011636", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011636", "type": "external" } ], "gene_names_uniprotkb": "MEP1; AMT1; G6331", "gene_names_refseq": "AMT1; MEP1", "protein_names_uniprotkb": "Ammonium transporter MEP1", "protein_names_refseq": "ammonium permease MEP1", "tax_id": 559292, "disease": "Rh deficiency syndrome (Disease Ontology:DOID:0050641); overhydrated hereditary stomatocytosis (Disease Ontology:DOID:0111562); Rh isoimmunization (Disease Ontology:DOID:4175); hemolytic anemia (Disease Ontology:DOID:583)", "pathway": " (sce:YGR121C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11486013;16847258;19779198;24374639;8062822;9046098;9169869;9234685", "class_list": "", "function": "Transporter for ammonium (both charged and uncharged NH3 and NH4) to use as a nitrogen source. Can also transport methylamine. The affinity of MEP1 is about twenty times lower than that of MEP2. MEP3 has the lowest affinity., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VUQ2", "ec_number_list": [], "go_molecular_function": "GO:0008519 ammonium channel activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane", "go_biological_process": "GO:0072488 ammonium transmembrane transport;GO:0019740 nitrogen utilization", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P40260-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40309-1", "uniprot_id": [ { "id": "KHA1_YEAST", "url": "https://www.uniprot.org/uniprot/P40309", "type": "external" } ], "mass": 97111.0, "length": 873, "protein_name": "K(+)/H(+) antiporter 1", "gene_name": "KHA1", "organism": "Yeast", "refseq_name": "Kha1p", "refseq_ac": [ { "id": "NP_012441", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012441", "type": "external" } ], "gene_names_uniprotkb": "KHA1; J0909", "gene_names_refseq": "KHA1", "protein_names_uniprotkb": "K(+)/H(+) antiporter 1", "protein_names_refseq": "Kha1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL094C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562106;16847258;17330950;18407956;19779198;22106047;23749301;24374639;33481703;33491328;7985424;8641269", "class_list": "", "function": "Potassium-proton antiport., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW90", "ec_number_list": [], "go_molecular_function": "GO:0015386 potassium:proton antiporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016020 membrane", "go_biological_process": "GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P40309-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40310-1", "uniprot_id": [ { "id": "TOK1_YEAST", "url": "https://www.uniprot.org/uniprot/P40310", "type": "external" } ], "mass": 77408.0, "length": 691, "protein_name": "Outward-rectifier potassium channel TOK1", "gene_name": "TOK1", "organism": "Yeast", "refseq_name": "Tok1p", "refseq_ac": [ { "id": "NP_012442", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012442", "type": "external" } ], "gene_names_uniprotkb": "TOK1; DUK1; J0911", "gene_names_refseq": "DUK1; TOK1; YKC1; YPK1", "protein_names_uniprotkb": "Outward-rectifier potassium channel TOK1; Two-domain outward rectifier K(+) channel YORK", "protein_names_refseq": "Tok1p", "tax_id": 559292, "disease": "Birk-Barel syndrome (Disease Ontology:DOID:0050675); heart conduction disease (Disease Ontology:DOID:10273); heart disease (Disease Ontology:DOID:114); primary pulmonary hypertension (Disease Ontology:DOID:14557); status epilepticus (Disease Ontology:DOID:1824); epilepsy (Disease Ontology:DOID:1826); transient cerebral ischemia (Disease Ontology:DOID:224); brain ischemia (Disease Ontology:DOID:2316); brain infarction (Disease Ontology:DOID:3454); pulmonary venoocclusive disease (Disease Ontology:DOID:5453); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); pulmonary hypertension (Disease Ontology:DOID:6432)", "pathway": " (sce:YJL093C); (R-SCE-1299287); (R-SCE-1299308); (R-SCE-1299316); (R-SCE-1299344); (R-SCE-1299361); (R-SCE-1299503); (R-SCE-5576886)", "pathway_count": 8, "publication_count": 10, "publication_id_list": "16847258;18407956;22329368;24374639;33491328;7651518;7985424;8626760;8641269;8723646", "class_list": "", "function": "Outwardly rectifying potassium channel., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 13, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW91;Q05721", "ec_number_list": [], "go_molecular_function": "GO:0015271 outward rectifier potassium channel activity;GO:0022841 potassium ion leak channel activity;GO:0005267 potassium channel activity;GO:0005249 voltage-gated potassium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0034702 monoatomic ion channel complex", "go_biological_process": "GO:0030007 intracellular potassium ion homeostasis;GO:0071805 potassium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P40310-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40312-1", "uniprot_id": [ { "id": "CYB5_YEAST", "url": "https://www.uniprot.org/uniprot/P40312", "type": "external" } ], "mass": 13297.0, "length": 120, "protein_name": "Cytochrome b5", "gene_name": "CYB5", "organism": "Yeast", "refseq_name": "Cyb5p", "refseq_ac": [ { "id": "NP_014288", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014288", "type": "external" } ], "gene_names_uniprotkb": "CYB5; N1949", "gene_names_refseq": "CYB5", "protein_names_uniprotkb": "Cytochrome b5", "protein_names_refseq": "Cyb5p", "tax_id": 559292, "disease": "methemoglobinemia and ambiguous genitalia (Disease Ontology:DOID:0112316); methemoglobinemia (Disease Ontology:DOID:10783); pyelonephritis (Disease Ontology:DOID:11400); stomatitis (Disease Ontology:DOID:9637)", "pathway": " (sce:YNL111C); (R-SCE-196836); (R-SCE-9609523)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "14562106;17322287;24374639;32597660;33491328;8181746;9090055;9169873", "class_list": "", "function": "Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases. It plays a role in fatty-acid desaturation and is also involved in several steps of the sterol biosynthesis pathway, particularly in the 4-demethylation of the 4,4'-dimethyl zymosterol., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W170", "ec_number_list": [], "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0020037 heme binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0016126 sterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P40312-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40314-1", "uniprot_id": [ { "id": "NACB2_YEAST", "url": "https://www.uniprot.org/uniprot/P40314", "type": "external" } ], "mass": 16620.0, "length": 149, "protein_name": "Nascent polypeptide-associated complex subunit beta-2", "gene_name": "BTT1", "organism": "Yeast", "refseq_name": "CCR4-NOT core subunit BTT1", "refseq_ac": [ { "id": "NP_010538", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010538", "type": "external" } ], "gene_names_uniprotkb": "BTT1; YD9320A.02", "gene_names_refseq": "BTT1", "protein_names_uniprotkb": "Nascent polypeptide-associated complex subunit beta-2; BTF3 homolog BTT1; Beta-2-NAC; NAC-beta-2", "protein_names_refseq": "CCR4-NOT core subunit BTT1", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR252W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10219998;14562095;14562106;17322287;24374639;33491328;8052529;9169867", "class_list": "", "function": "Acts as a component of the nascent polypeptide-associated complex (NAC), which promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane. Also blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. BTT1 may act as a transcription factor that exert a negative effect on the expression of several genes that are transcribed by RNA polymerase II., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSN2", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005854 nascent polypeptide-associated complex;GO:0030015 CCR4-NOT core complex", "go_biological_process": "GO:0051083 'de novo' cotranslational protein folding;GO:0006351 DNA-templated transcription;GO:0015031 protein transport;GO:0006613 cotranslational protein targeting to membrane", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P40314-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40317-1", "uniprot_id": [ { "id": "SOK1_YEAST", "url": "https://www.uniprot.org/uniprot/P40317", "type": "external" } ], "mass": 101082.0, "length": 901, "protein_name": "Protein SOK1", "gene_name": "SOK1", "organism": "Yeast", "refseq_name": "Sok1p", "refseq_ac": [ { "id": "NP_010289", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010289", "type": "external" } ], "gene_names_uniprotkb": "SOK1; YD8119.12C", "gene_names_refseq": "SOK1", "protein_names_uniprotkb": "Protein SOK1", "protein_names_refseq": "Sok1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR006C)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "17287358;17330950;18407956;19779198;19795423;19823750;20702584;21126336;23749301;24374639;32597660;33481703;33491328;8065298;9169867", "class_list": "", "function": "High copy suppressor of a cyclic AMP-dependent protein kinase mutant., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 30, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRZ4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0007165 signal transduction;GO:0141156 cAMP/PKA signal transduction", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P40317-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40328-1", "uniprot_id": [ { "id": "TBP6_YEAST", "url": "https://www.uniprot.org/uniprot/P40328", "type": "external" } ], "mass": 85300.0, "length": 754, "protein_name": "Microtubule severing ATPase YTA6", "gene_name": "YTA6", "organism": "Yeast", "refseq_name": "putative AAA family ATPase YTA6", "refseq_ac": [ { "id": "NP_015251", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015251", "type": "external" } ], "gene_names_uniprotkb": "YTA6; LPF11C", "gene_names_refseq": "YTA6", "protein_names_uniprotkb": "Microtubule severing ATPase YTA6; 5.6.1.1; Tat-binding homolog 6", "protein_names_refseq": "putative AAA family ATPase YTA6", "tax_id": 559292, "disease": "nicotine dependence (Disease Ontology:DOID:0050742); hereditary spastic paraplegia 4 (Disease Ontology:DOID:0110792); hereditary spastic paraplegia (Disease Ontology:DOID:2476)", "pathway": " (sce:YPL074W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "14562106;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21177495;23749301;24374639;3025612;30516470;32597660;32639961;33481703;33491328;7754704;9169875", "class_list": "", "function": "May function as an ATP-dependent microtubule severing protein., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 18, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3U2;P40324;Q02845;Q05773", "ec_number_list": [], "go_molecular_function": "GO:0008568 microtubule severing ATPase activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005938 cell cortex", "go_biological_process": "GO:0051013 microtubule severing;GO:0045727 positive regulation of translation", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P40328-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40354-1", "uniprot_id": [ { "id": "NTA1_YEAST", "url": "https://www.uniprot.org/uniprot/P40354", "type": "external" } ], "mass": 51897.0, "length": 457, "protein_name": "Protein N-terminal amidase", "gene_name": "NTA1", "organism": "Yeast", "refseq_name": "amidase", "refseq_ac": [ { "id": "NP_012596", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012596", "type": "external" } ], "gene_names_uniprotkb": "NTA1; J1742", "gene_names_refseq": "DEA1; NTA1", "protein_names_uniprotkb": "Protein N-terminal amidase; 3.5.1.-; NT-amidase", "protein_names_refseq": "amidase", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR062C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;19684113;21177495;24374639;33491328;7744855;8641269;8840504", "class_list": "", "function": "Deamidates N-terminal Asn and Gln. Component of a targeting complex in the N-end rule pathway., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWN3", "ec_number_list": [], "go_molecular_function": "GO:0008418 protein-N-terminal asparagine amidohydrolase activity;GO:0070773 protein-N-terminal glutamine amidohydrolase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0031365 N-terminal protein amino acid modification;GO:0030163 protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P40354-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40363-1", "uniprot_id": [ { "id": "SFGH_YEAST", "url": "https://www.uniprot.org/uniprot/P40363", "type": "external" } ], "mass": 33934.0, "length": 299, "protein_name": "S-formylglutathione hydrolase", "gene_name": "HRE299; J1102", "organism": "Yeast", "refseq_name": "S-formylglutathione hydrolase", "refseq_ac": [ { "id": "NP_012467", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012467", "type": "external" } ], "gene_names_uniprotkb": "HRE299; J1102", "gene_names_refseq": "", "protein_names_uniprotkb": "S-formylglutathione hydrolase; 3.1.2.12; FGH", "protein_names_refseq": "S-formylglutathione hydrolase", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL068C); (R-SCE-156590)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "10427036;14562106;18707125;22814378;22906720;24374639;33491328;7762302;8641269", "class_list": "", "function": "Serine hydrolase involved in the detoxification of formaldehyde., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWB5", "ec_number_list": [ { "id": "3.1.2.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.12", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0052689 carboxylic ester hydrolase activity;GO:0018738 S-formylglutathione hydrolase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0046294 formaldehyde catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P40363-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40413-1", "uniprot_id": [ { "id": "TCPE_YEAST", "url": "https://www.uniprot.org/uniprot/P40413", "type": "external" } ], "mass": 61914.0, "length": 562, "protein_name": "T-complex protein 1 subunit epsilon", "gene_name": "CCT5", "organism": "Yeast", "refseq_name": "chaperonin-containing T-complex subunit CCT5", "refseq_ac": [ { "id": "NP_012598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012598", "type": "external" } ], "gene_names_uniprotkb": "CCT5; J1752; TCP5", "gene_names_refseq": "CCT5; TCP5", "protein_names_uniprotkb": "T-complex protein 1 subunit epsilon; CCT-epsilon; TCP-1-epsilon", "protein_names_refseq": "chaperonin-containing T-complex subunit CCT5", "tax_id": 559292, "disease": "intrinsic cardiomyopathy (Disease Ontology:DOID:0060036); autosomal recessive sensory neuropathy with spastic paraplegia (Disease Ontology:DOID:0061188); Bardet-Biedl syndrome 10 (Disease Ontology:DOID:0110132); sensory peripheral neuropathy (Disease Ontology:DOID:2491)", "pathway": " (sce:YJR064W); (R-SCE-390471); (R-SCE-6814122)", "pathway_count": 3, "publication_count": 7, "publication_id_list": "23749301;24374639;32597660;33481703;33491328;8641269;8840504", "class_list": "", "function": "Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. In yeast may play a role in mitotic spindle formation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWN5", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity;GO:0140662 ATP-dependent protein folding chaperone", "go_cellular_component": "GO:0005832 chaperonin-containing T-complex", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P40413-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40434-1", "uniprot_id": [ { "id": "YIR7_YEAST", "url": "https://www.uniprot.org/uniprot/P40434", "type": "external" } ], "mass": 197512.0, "length": 1758, "protein_name": "Y' element ATP-dependent helicase YIL177C", "gene_name": "", "organism": "Yeast", "refseq_name": "Y' element ATP-dependent helicase", "refseq_ac": [ { "id": "NP_012092", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012092", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Y' element ATP-dependent helicase YIL177C; 5.6.2.-", "protein_names_refseq": "Y' element ATP-dependent helicase", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL177C)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "24374639;9169870;9837911", "class_list": "", "function": "Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVB6", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003676 nucleic acid binding;GO:0004386 helicase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0000722 telomere maintenance via recombination", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P40434-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40442-1", "uniprot_id": [ { "id": "CSS1_YEAST", "url": "https://www.uniprot.org/uniprot/P40442", "type": "external" } ], "mass": 99736.0, "length": 995, "protein_name": "Secreted protein CSS1", "gene_name": "CSS1", "organism": "Yeast", "refseq_name": "Css1p", "refseq_ac": [ { "id": "NP_012097", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012097", "type": "external" } ], "gene_names_uniprotkb": "CSS1; HPF1'; YI9402.07C", "gene_names_refseq": "CSS1; HZY1", "protein_names_uniprotkb": "Secreted protein CSS1; Condition specific secretion protein 1; Haze protective factor 1'", "protein_names_refseq": "Css1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL169C)", 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"P40445-1", "uniprot_id": [ { "id": "YIQ6_YEAST", "url": "https://www.uniprot.org/uniprot/P40445", "type": "external" } ], "mass": 61898.0, "length": 542, "protein_name": "Uncharacterized transporter YIL166C", "gene_name": "", "organism": "Yeast", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized transporter YIL166C", "protein_names_refseq": "", "tax_id": 559292, "disease": "neurodegenerative disease (Disease Ontology:DOID:1289); Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (sce:YIL166C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "16847258;17322287;24374639;9169870", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVC1", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015116 sulfate transmembrane transporter activity;GO:1901682 sulfur compound transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:1902358 sulfate transmembrane transport;GO:0000316 sulfite transmembrane transport;GO:0072348 sulfur compound transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P40445-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40451-1", "uniprot_id": [ { "id": "AIM20_YEAST", "url": "https://www.uniprot.org/uniprot/P40451", "type": "external" } ], "mass": 22840.0, "length": 204, "protein_name": "Altered inheritance of mitochondria protein 20", "gene_name": "AIM20", "organism": "Yeast", "refseq_name": "Aim20p", "refseq_ac": [ { "id": "NP_012108", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012108", "type": "external" } ], "gene_names_uniprotkb": "AIM20", "gene_names_refseq": "AIM20", "protein_names_uniprotkb": "Altered inheritance of mitochondria protein 20", "protein_names_refseq": "Aim20p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL158W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;18617996;19300474;20472512;23749301;24374639;33481703;9169870", "class_list": "", "function": "Involved in cell cycle progression and surviving DNA damage., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, 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"kg_view_protein": true }, { "uniprot_canonical_ac": "P40459-1", "uniprot_id": [ { "id": "PANC_YEAST", "url": "https://www.uniprot.org/uniprot/P40459", "type": "external" } ], "mass": 35032.0, "length": 309, "protein_name": "Pantoate--beta-alanine ligase", "gene_name": "PAN6", "organism": "Yeast", "refseq_name": "pantoate--beta-alanine ligase PAN6", "refseq_ac": [ { "id": "NP_012121", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012121", "type": "external" } ], "gene_names_uniprotkb": "PAN6", "gene_names_refseq": "PAN6", "protein_names_uniprotkb": "Pantoate--beta-alanine ligase; 6.3.2.1; Pantoate-activating enzyme; Pantothenate synthetase", "protein_names_refseq": "pantoate--beta-alanine ligase PAN6", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL145C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11154694;12748633;14562095;14562106;24374639;33491328;9169870", "class_list": "", "function": "Required for pantothenic acid biosynthesis., [UniProtKB, 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"glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVE2", "ec_number_list": [ { "id": "6.3.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.2.1", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004592 pantoate-beta-alanine ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0015940 pantothenate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P40459-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40463-1", "uniprot_id": [ { "id": "VHS2_YEAST", "url": "https://www.uniprot.org/uniprot/P40463", "type": "external" } ], "mass": 47961.0, "length": 436, "protein_name": "Protein VHS2", "gene_name": "VHS2", "organism": "Yeast", "refseq_name": "Vhs2p", "refseq_ac": [ { "id": "NP_012131", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012131", "type": "external" } ], "gene_names_uniprotkb": "VHS2", "gene_names_refseq": "VHS2", "protein_names_uniprotkb": "Protein VHS2; Viable in a HAL3 SIT4 background protein 2", "protein_names_refseq": "Vhs2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL135C)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "12518319;14562095;14562106;15665377;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;24374639;30516470;32597660;33229814;33481703;33491328;9169870", "class_list": "", "function": "Can suppress the synthetic lethality of the hal3 sit4 double mutation when overexpressed, suggesting that it is involved in the G1-S transition., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 15, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 15, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 15, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 67, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 14, "binding_glycan_count": 0, "secondary_ac_list": "D6VVF1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0034605 cellular response to heat;GO:0030950 establishment or maintenance of actin cytoskeleton polarity;GO:0032186 cellular bud neck septin ring organization", "synthesized_glycan_count": 0, "hit_score": 4.0, "record_id": "P40463-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40464-1", "uniprot_id": [ { "id": "FLX1_YEAST", "url": "https://www.uniprot.org/uniprot/P40464", "type": "external" } ], "mass": 34409.0, "length": 311, "protein_name": "Mitochondrial FAD carrier protein FLX1", "gene_name": "FLX1", "organism": "Yeast", "refseq_name": "flavin adenine dinucleotide transporter FLX1", "refseq_ac": [ { "id": "NP_012132", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012132", "type": "external" } ], "gene_names_uniprotkb": "FLX1", "gene_names_refseq": "FLX1", "protein_names_uniprotkb": "Mitochondrial FAD carrier protein FLX1", "protein_names_refseq": "flavin adenine dinucleotide transporter FLX1", "tax_id": 559292, "disease": "multiple acyl-CoA dehydrogenase deficiency (Disease Ontology:DOID:0060358)", "pathway": " (sce:YIL134W); (R-SCE-196757)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "17322287;24374639;8631763;9169870", "class_list": "", "function": "Transport of FAD from the cytosol to the mitochondrial matrix., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, 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"0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40467-1", "uniprot_id": [ { "id": "ASG1_YEAST", "url": "https://www.uniprot.org/uniprot/P40467", "type": "external" } ], "mass": 108781.0, "length": 964, "protein_name": "Activator of stress genes 1", "gene_name": "ASG1", "organism": "Yeast", "refseq_name": "Asg1p", "refseq_ac": [ { "id": "NP_012136", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012136", "type": "external" } ], "gene_names_uniprotkb": "ASG1", "gene_names_refseq": "ASG1", "protein_names_uniprotkb": "Activator of stress genes 1", "protein_names_refseq": "Asg1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL130W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "11353088;14562095;14562106;15665377;16273108;17330950;17563356;18407956;19779198;19795423;19823750;20190278;22814378;23749301;24374639;32597660;33481703;33491328;9169870", "class_list": "", "function": 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"reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VVF7;Q45U13", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P40467-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40473-1", "uniprot_id": [ { "id": "POG1_YEAST", "url": "https://www.uniprot.org/uniprot/P40473", "type": "external" } ], "mass": 39498.0, "length": 351, "protein_name": "Transcriptional activator POG1", "gene_name": "POG1", "organism": "Yeast", "refseq_name": "Pog1p", "refseq_ac": [ { "id": "NP_012144", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012144", "type": "external" } ], "gene_names_uniprotkb": "POG1", "gene_names_refseq": "POG1", "protein_names_uniprotkb": "Transcriptional activator POG1; Promoter of growth protein 1", "protein_names_refseq": "Pog1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL122W)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "12464632;14562095;14562106;14574415;16278933;17986087;18407956;19779198;21126336;21177495;22218487;23749301;24374639;24909858;25073408;32597660;33229814;33481703;33491328;34965436;9169870;9927449", "class_list": "", "function": "Transcriptional activator which promotes cell cycle recovery with CLN2, after pheromone induced G1 arrest, probably inhibiting the ability of STE20 to activate the pheromone response pathway. Binds the promoters of genes that function in cell cycle regulation, cytoskeletal organization, and spindle assembly. May also be involved in stress-resistance., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 9, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 9, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 9, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D6VVG5", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051301 cell division;GO:0000321 re-entry into mitotic cell cycle after pheromone arrest;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 3.3, "record_id": "P40473-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40474-1", "uniprot_id": [ { "id": "QDR2_YEAST", "url": "https://www.uniprot.org/uniprot/P40474", "type": "external" } ], "mass": 59618.0, "length": 542, "protein_name": "Quinidine resistance protein 2", "gene_name": "QDR2", "organism": "Yeast", "refseq_name": "cation transporter", "refseq_ac": [ { "id": "NP_012145", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012145", "type": "external" } ], "gene_names_uniprotkb": "QDR2", "gene_names_refseq": "QDR2", "protein_names_uniprotkb": "Quinidine resistance protein 2", "protein_names_refseq": "cation transporter", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL121W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "15215105;16847258;17189489;17322287;17563356;18407956;19779198;20702584;21126336;21177495;22218487;23749301;24374639;32597660;33481703;33491328;9169870", "class_list": "", "function": "Multidrug resistance transporter involved in resistance and adaptation to quinidine and to the herbicide barban (4-chloro-2-butynyl [3-chlorophenyl] carbamate). Implicated in potassium uptake., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVG6", "ec_number_list": [], "go_molecular_function": "GO:0042910 xenobiotic transmembrane transporter activity;GO:0008324 monoatomic cation transmembrane transporter activity;GO:0022857 transmembrane transporter activity;GO:0015565 threonine efflux transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0055085 transmembrane transport;GO:0060003 copper ion export;GO:1990573 potassium ion import across plasma membrane;GO:0032973 amino acid export across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P40474-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40475-1", "uniprot_id": [ { "id": "QDR1_YEAST", "url": "https://www.uniprot.org/uniprot/P40475", "type": "external" } ], "mass": 61759.0, "length": 563, "protein_name": "Quinidine resistance protein 1", "gene_name": "QDR1", "organism": "Yeast", "refseq_name": "multidrug transporter", "refseq_ac": [ { "id": "NP_012146", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012146", "type": "external" } ], "gene_names_uniprotkb": "QDR1", "gene_names_refseq": "QDR1", "protein_names_uniprotkb": "Quinidine resistance protein 1", "protein_names_refseq": "multidrug transporter", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL120W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11302822;16847258;24374639;9169870", "class_list": "", "function": "Multidrug resistance transporter involved in resistance and adaptation to quinidine and ketoconazole., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVG7", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015562 efflux transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0055085 transmembrane transport;GO:0030476 ascospore wall assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P40475-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40478-1", "uniprot_id": [ { "id": "VDAC2_YEAST", "url": "https://www.uniprot.org/uniprot/P40478", "type": "external" } ], "mass": 31177.0, "length": 281, "protein_name": "Non-selective voltage-gated ion channel 2", "gene_name": "POR2", "organism": "Yeast", "refseq_name": "putative porin POR2", "refseq_ac": [ { "id": "NP_012152", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012152", "type": "external" } ], "gene_names_uniprotkb": "POR2", "gene_names_refseq": "POR2", "protein_names_uniprotkb": "Non-selective voltage-gated ion channel 2; Outer mitochondrial membrane protein porin 2; VDAC-2; Voltage-dependent anion-selective channel protein 2", "protein_names_refseq": "putative porin POR2", "tax_id": 559292, "disease": "Parkinsonism (Disease Ontology:DOID:0080855); prostate cancer (Disease Ontology:DOID:10283); neurodegenerative disease (Disease Ontology:DOID:1289); Parkinson's disease (Disease Ontology:DOID:14330); temporal lobe epilepsy (Disease Ontology:DOID:3328); myocardial infarction (Disease Ontology:DOID:5844); retinal degeneration (Disease Ontology:DOID:8466)", "pathway": " (sce:YIL114C); (R-SCE-5205685); (R-SCE-70268)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "17322287;19779198;24374639;9169870;9315631;9435273", "class_list": "", "function": "Catalyzes the scrambling of phospholipids across the outer mitochondrial membrane; the mechanism is unrelated to channel activity and is capable of translocating both anionic and zwitterionic phospholipids., [UniProtKB, UniProtKB]; Non-selective voltage-gated ion channel that mediates the transport of anions and cations through the mitochondrion outer membrane. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity). Does not confer permeability to NADH (PubMed:9435273)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVH3", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0015288 porin activity;GO:0008308 voltage-gated monoatomic anion channel activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0046930 pore complex", "go_biological_process": "GO:0006869 lipid transport;GO:0045454 cell redox homeostasis;GO:0051027 DNA transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P40478-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40481-1", "uniprot_id": [ { "id": "HPM1_YEAST", "url": "https://www.uniprot.org/uniprot/P40481", "type": "external" } ], "mass": 42515.0, "length": 377, "protein_name": "Histidine protein methyltransferase 1", "gene_name": "HPM1", "organism": "Yeast", "refseq_name": "protein-histidine N-methyltransferase", "refseq_ac": [ { "id": "NP_012156", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012156", "type": "external" } ], "gene_names_uniprotkb": "HPM1; MNI1", "gene_names_refseq": "HPM1; MNI1", "protein_names_uniprotkb": "Histidine protein methyltransferase 1; 2.1.1.85; Mitotic exit network interactor 1", "protein_names_refseq": "protein-histidine N-methyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL110W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;15166135;16234568;17322287;20864530;24374639;24865971;26826131;33491328;9169870", "class_list": "", "function": "Protein-histidine N-methyltransferase that mediates methylation of RPL3 at 'His-243' (PubMed:20864530, PubMed:24865971). Methylates ribosome-associated RPL3, but not free RPL3, thereby regulating 60S subunit assembly (PubMed:24865971, PubMed:26826131). In addition to RPL3, mediates His methylation of other proteins (PubMed:26826131)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVH7", "ec_number_list": [ { "id": "2.1.1.85", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.85", "type": "external" } ], "go_molecular_function": "GO:0018064 protein-L-histidine N-tele-methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006417 regulation of translation;GO:0000027 ribosomal large subunit assembly;GO:0042038 peptidyl-histidine methylation, to form tele-methylhistidine;GO:0045903 positive regulation of translational fidelity", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P40481-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40486-1", "uniprot_id": [ { "id": "SHQ1_YEAST", "url": "https://www.uniprot.org/uniprot/P40486", "type": "external" } ], "mass": 59151.0, "length": 507, "protein_name": "Protein SHQ1", "gene_name": "SHQ1", "organism": "Yeast", "refseq_name": "Hsp90 cochaperone SHQ1", "refseq_ac": [ { "id": "NP_012162", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012162", "type": "external" } ], "gene_names_uniprotkb": "SHQ1", "gene_names_refseq": "SHQ1", "protein_names_uniprotkb": "Protein SHQ1; Small nucleolar RNAs of the box H/ACA family quantitative accumulation protein 1", "protein_names_refseq": "Hsp90 cochaperone SHQ1", "tax_id": 559292, "disease": "dystonia 35, childhood-onset (Disease Ontology:DOID:0060955)", "pathway": " (sce:YIL104C); (R-SCE-171319)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "12228251;14562095;14562106;15798213;24374639;33491328;9169870", "class_list": "", "function": "Involved in the early biogenesis steps of box H/ACA snoRNP assembly., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVI3", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0000493 box H/ACA snoRNP assembly", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P40486-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40489-1", "uniprot_id": [ { "id": "XBP1_YEAST", "url": "https://www.uniprot.org/uniprot/P40489", "type": "external" } ], "mass": 72687.0, "length": 647, "protein_name": "Transcriptional repressor XBP1", "gene_name": "XBP1", "organism": "Yeast", "refseq_name": "Xbp1p", "refseq_ac": [ { "id": "NP_012165", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012165", "type": "external" } ], "gene_names_uniprotkb": "XBP1", "gene_names_refseq": "XBP1", "protein_names_uniprotkb": "Transcriptional repressor XBP1; XhoI site-binding protein 1", "protein_names_refseq": "Xbp1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL101C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562106;18407956;19684113;21467995;23749301;24374639;3141213;32597660;33491328;9169870;9343412", "class_list": "", "function": "Transcriptional repressor which binds to the consensus sequence 5'-GCCTCGA[G/A]G[C/A]-3'. Represses CLN1 transcription., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVI7;Q12688", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0030907 MBF transcription complex;GO:0033309 SBF transcription complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0034605 cellular response to heat;GO:0042149 cellular response to glucose starvation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P40489-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40491-1", "uniprot_id": [ { "id": "FMC1_YEAST", "url": "https://www.uniprot.org/uniprot/P40491", "type": "external" } ], "mass": 18364.0, "length": 155, "protein_name": "ATP synthase assembly factor FMC1, mitochondrial", "gene_name": "FMC1", "organism": "Yeast", "refseq_name": "Fmc1p", "refseq_ac": [ { "id": "NP_012168", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012168", "type": "external" } ], "gene_names_uniprotkb": "FMC1", "gene_names_refseq": "FMC1", "protein_names_uniprotkb": "ATP synthase assembly factor FMC1, mitochondrial; Formation of mitochondrial complexes protein 1", "protein_names_refseq": "Fmc1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL098C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11096112;14562095;14562106;14576278;17322287;24374639;9169870", "class_list": "", "function": "Needed for the assembly of the mitochondrial F1-F0 complex at high temperature., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVI9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0016236 macroautophagy;GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P40491-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40493-1", "uniprot_id": [ { "id": "BMT5_YEAST", "url": "https://www.uniprot.org/uniprot/P40493", "type": "external" } ], "mass": 39402.0, "length": 336, "protein_name": "25S rRNA (uridine(2634)-N(3))-methyltransferase", "gene_name": "BMT5", "organism": "Yeast", "refseq_name": "25S rRNA (uracil2634-N3)-methyltransferase", "refseq_ac": [ { "id": "NP_012170", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012170", "type": "external" } ], "gene_names_uniprotkb": "BMT5", "gene_names_refseq": "BMT5", "protein_names_uniprotkb": "25S rRNA (uridine(2634)-N(3))-methyltransferase; 2.1.1.313; Base methyltransferase of 25S RNA 5", "protein_names_refseq": "25S rRNA (uracil2634-N3)-methyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL096C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;21858014;24335083;24374639;32597660;33491328;9169870", "class_list": "", "function": "S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(3) position of uridine 2634 (m3U2634) in 25S rRNA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVJ1", "ec_number_list": [ { "id": "2.1.1.313", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.313", "type": "external" } ], "go_molecular_function": "GO:0008757 S-adenosylmethionine-dependent methyltransferase activity;GO:0070042 rRNA (uridine-N3-)-methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0070475 rRNA base methylation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P40493-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40496-1", "uniprot_id": [ { "id": "RT25_YEAST", "url": "https://www.uniprot.org/uniprot/P40496", "type": "external" } ], "mass": 30513.0, "length": 264, "protein_name": "Small ribosomal subunit protein mS23", "gene_name": "RSM25", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein mS23 RSM25", "refseq_ac": [ { "id": "NP_012173", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012173", "type": "external" } ], "gene_names_uniprotkb": "RSM25", "gene_names_refseq": "RSM25; mS23", "protein_names_uniprotkb": "Small ribosomal subunit protein mS23; 37S ribosomal protein S25, mitochondrial", "protein_names_refseq": "mitochondrial 37S ribosomal protein mS23 RSM25", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL093C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "11278769;12392552;14562095;14562106;16823961;22814378;24374639;25609543;28154081;32597660;9169870", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVJ4", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P40496-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40499-1", "uniprot_id": [ { "id": "ICE2_YEAST", "url": "https://www.uniprot.org/uniprot/P40499", "type": "external" } ], "mass": 56333.0, "length": 491, "protein_name": "Protein ICE2", "gene_name": "ICE2", "organism": "Yeast", "refseq_name": "Ice2p", "refseq_ac": [ { "id": "NP_012176", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012176", "type": "external" } ], "gene_names_uniprotkb": "ICE2", "gene_names_refseq": "ICE2", "protein_names_uniprotkb": "Protein ICE2; Inheritance of cortical ER protein 2", "protein_names_refseq": "Ice2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL090W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;14562106;16847258;17322287;24374639;9169870", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VVJ7;Q6B2T7", "ec_number_list": [], "go_molecular_function": "GO:0004865 protein serine/threonine phosphatase inhibitor activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0097038 perinuclear endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0032541 cortical endoplasmic reticulum", "go_biological_process": "GO:0000921 septin ring assembly;GO:0006882 intracellular zinc ion homeostasis;GO:0031204 post-translational protein targeting to membrane, translocation;GO:0036228 protein localization to nuclear inner membrane;GO:0048309 endoplasmic reticulum inheritance", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P40499-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40504-1", "uniprot_id": [ { "id": "KTR7_YEAST", "url": "https://www.uniprot.org/uniprot/P40504", "type": "external" } ], "mass": 61438.0, "length": 517, "protein_name": "Probable mannosyltransferase KTR7", "gene_name": "KTR7", "organism": "Yeast", "refseq_name": "putative mannosyltransferase", "refseq_ac": [ { "id": "NP_012181", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012181", "type": "external" } ], "gene_names_uniprotkb": "KTR7", "gene_names_refseq": "KTR7", "protein_names_uniprotkb": "Probable mannosyltransferase KTR7; 2.4.1.-", "protein_names_refseq": "putative mannosyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL085C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "14562106;24374639;9090056;9169870", "class_list": "glycogene;glycosyltransferase", "function": "Possible glycosyltransferase that transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VVK1", "ec_number_list": [], "go_molecular_function": "GO:0000026 alpha-1,2-mannosyltransferase activity;GO:0000030 mannosyltransferase activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0016020 membrane", "go_biological_process": "GO:0000032 cell wall mannoprotein biosynthetic process;GO:0006487 protein N-linked glycosylation;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P40504-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40511-1", "uniprot_id": [ { "id": "SPO22_YEAST", "url": "https://www.uniprot.org/uniprot/P40511", "type": "external" } ], "mass": 112434.0, "length": 975, "protein_name": "Sporulation-specific protein 22", "gene_name": "SPO22", "organism": "Yeast", "refseq_name": "Spo22p", "refseq_ac": [ { "id": "NP_012192", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012192", "type": "external" } ], "gene_names_uniprotkb": "SPO22", "gene_names_refseq": "SPO22; ZIP4", "protein_names_uniprotkb": "Sporulation-specific protein 22", "protein_names_refseq": "Spo22p", "tax_id": 559292, "disease": "X-linked spermatogenic failure 2 (Disease Ontology:DOID:0070185)", "pathway": " (sce:YIL073C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11101837;11470404;12775844;24374639;33229814;33491328;9169870", "class_list": "", "function": "Involved in chromosome segregation during sporulation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VVL1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005634 nucleus", "go_biological_process": "GO:0016925 protein sumoylation;GO:0033235 positive regulation of protein sumoylation;GO:0007129 homologous chromosome pairing at meiosis;GO:0007131 reciprocal meiotic recombination;GO:0035825 homologous recombination", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P40511-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40512-1", "uniprot_id": [ { "id": "CSN11_YEAST", "url": "https://www.uniprot.org/uniprot/P40512", "type": "external" } ], "mass": 51288.0, "length": 444, "protein_name": "Cop9 signalosome complex subunit 11", "gene_name": "PCI8", "organism": "Yeast", "refseq_name": "Pci8p", "refseq_ac": [ { "id": "NP_085069", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_085069", "type": "external" } ], "gene_names_uniprotkb": "PCI8; CSN11; YIH1", "gene_names_refseq": "CSN11; PCI8; YIH1; YIL071W", "protein_names_uniprotkb": "Cop9 signalosome complex subunit 11; Proteasome-COP9 signalosome-eIF3 domain protein 8", "protein_names_refseq": "Pci8p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL071C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "11457827;11805826;12186635;12446563;14562095;14562106;24374639;33491328;9169870;9605331", "class_list": "", "function": "Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes The CSN complex is involved in the regulation of the mating pheromone response. PCI8 may also be involved in transcriptional and translational control., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVL3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0008180 COP9 signalosome", "go_biological_process": "GO:0000338 protein deneddylation;GO:2000434 regulation of protein neddylation;GO:0000754 adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P40512-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40513-1", "uniprot_id": [ { "id": "MAM33_YEAST", "url": "https://www.uniprot.org/uniprot/P40513", "type": "external" } ], "mass": 30132.0, "length": 266, "protein_name": "Mitochondrial acidic protein MAM33", "gene_name": "MAM33", "organism": "Yeast", "refseq_name": "Mam33p", "refseq_ac": [ { "id": "NP_012194", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012194", "type": "external" } ], "gene_names_uniprotkb": "MAM33", "gene_names_refseq": "MAM33", "protein_names_uniprotkb": "Mitochondrial acidic protein MAM33", "protein_names_refseq": "Mam33p", "tax_id": 559292, "disease": "combined oxidative phosphorylation deficiency 33 (Disease Ontology:DOID:0111495)", "pathway": " (sce:YIL070C); (R-SCE-8980692); (R-SCE-9013106)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "14562106;17322287;18407956;24374639;30516470;33491328;9169870;9559539", "class_list": "", "function": "Not known. Binds to the sorting sequence of cytochrome b2., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VVL4;Q6Q5P4", "ec_number_list": [], "go_molecular_function": "GO:0097177 mitochondrial ribosome binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0009060 aerobic respiration;GO:0042256 cytosolic ribosome assembly;GO:1902775 mitochondrial large ribosomal subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P40513-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40516-1", "uniprot_id": [ { "id": "EFM4_YEAST", "url": "https://www.uniprot.org/uniprot/P40516", "type": "external" } ], "mass": 25486.0, "length": 229, "protein_name": "Protein-lysine N-methyltransferase EFM4", "gene_name": "EFM4", "organism": "Yeast", "refseq_name": "Efm4p", "refseq_ac": [ { "id": "NP_012200", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012200", "type": "external" } ], "gene_names_uniprotkb": "EFM4; SEE1", "gene_names_refseq": "EFM4; SEE1", "protein_names_uniprotkb": "Protein-lysine N-methyltransferase EFM4; 2.1.1.-; Elongation factor methyltransferase 4; Secretion and early endocytosis protein 1", "protein_names_refseq": "Efm4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL064W); (R-SCE-8876725)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "14562095;14562106;17322287;19160456;20510667;22522802;24374639;24517342;25231983;38199565;9169870", "class_list": "", "function": "S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha (TEF1 and TEF2) at 'Lys-316'. May play a role in intracellular transport., [UniProtKB, HAMAP, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVM0;Q6B2R5", "ec_number_list": [ { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" } ], "go_molecular_function": "GO:0016279 protein-lysine N-methyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006417 regulation of translation;GO:0016192 vesicle-mediated transport;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P40516-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40518-1", "uniprot_id": [ { "id": "ARPC5_YEAST", "url": "https://www.uniprot.org/uniprot/P40518", "type": "external" } ], "mass": 17134.0, "length": 154, "protein_name": "Actin-related protein 2/3 complex subunit 5", "gene_name": "ARC15", "organism": "Yeast", "refseq_name": "Arc15p", "refseq_ac": [ { "id": "NP_012202", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012202", "type": "external" } ], "gene_names_uniprotkb": "ARC15", "gene_names_refseq": "ARC15", "protein_names_uniprotkb": "Actin-related protein 2/3 complex subunit 5; Arp2/3 complex 16 kDa subunit; p16-ARC", "protein_names_refseq": "Arc15p", "tax_id": 559292, "disease": "congenital hypothyroidism (Disease Ontology:DOID:0050328); immunodeficiency 113 (Disease Ontology:DOID:0051056); candidiasis (Disease Ontology:DOID:1508); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": " (sce:YIL062C); (R-SCE-2029482); (R-SCE-5663213); (R-SCE-6798695)", "pathway_count": 4, "publication_count": 10, "publication_id_list": "11248049;14562106;17322287;18407956;23749301;24374639;33481703;33491328;9169870;9210376", "class_list": "", "function": "Functions as a component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVM2", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0015629 actin cytoskeleton;GO:0030863 cortical cytoskeleton;GO:0005885 Arp2/3 protein complex;GO:0030479 actin cortical patch", "go_biological_process": "GO:0034314 Arp2/3 complex-mediated actin nucleation;GO:0045010 actin nucleation;GO:0030833 regulation of actin filament polymerization;GO:0000001 mitochondrion inheritance;GO:0044396 actin cortical patch organization", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P40518-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40522-1", "uniprot_id": [ { "id": "VHR1_YEAST", "url": "https://www.uniprot.org/uniprot/P40522", "type": "external" } ], "mass": 71421.0, "length": 640, "protein_name": "Transcription factor VHR1", "gene_name": "VHR1", "organism": "Yeast", "refseq_name": "Vhr1p", "refseq_ac": [ { "id": "NP_012208", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012208", "type": "external" } ], "gene_names_uniprotkb": "VHR1", "gene_names_refseq": "VHR1", "protein_names_uniprotkb": "Transcription factor VHR1; VHT1 regulator 1", "protein_names_refseq": "Vhr1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL056W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562095;14562106;15713640;16533810;17330950;19779198;23749301;24374639;32597660;33481703;33491328;9169870", "class_list": "", "function": "Transcription factor that binds to the VHRE consensus sequence in promoters of VHT1 and BIO5, and regulates their biotin-dependent expression., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VVM6", "ec_number_list": [], "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:1990383 cellular response to biotin starvation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P40522-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40525-1", "uniprot_id": [ { "id": "RL34B_YEAST", "url": "https://www.uniprot.org/uniprot/P40525", "type": "external" } ], "mass": 13641.0, "length": 121, "protein_name": "Large ribosomal subunit protein eL34B", "gene_name": "RPL34B", "organism": "Yeast", "refseq_name": "60S ribosomal protein eL34 RPL34B", "refseq_ac": [ { "id": "NP_012212", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012212", "type": "external" } ], "gene_names_uniprotkb": "RPL34B", "gene_names_refseq": "RPL34B", "protein_names_uniprotkb": "Large ribosomal subunit protein eL34B; 60S ribosomal protein L34-B", "protein_names_refseq": "60S ribosomal protein eL34 RPL34B", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL052C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;22096102;24374639;24524803;32597660;9169870;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVM9", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0042254 ribosome biogenesis;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P40525-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40528-1", "uniprot_id": [ { "id": "S53A1_YEAST", "url": "https://www.uniprot.org/uniprot/P40528", "type": "external" } ], "mass": 104218.0, "length": 902, "protein_name": "Phosphate exporter SYG1", "gene_name": "SYG1", "organism": "Yeast", "refseq_name": "Syg1p", "refseq_ac": [ { "id": "NP_012217", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012217", "type": "external" } ], "gene_names_uniprotkb": "SYG1", "gene_names_refseq": "SYG1", "protein_names_uniprotkb": "Phosphate exporter SYG1", "protein_names_refseq": "Syg1p", "tax_id": 559292, "disease": "basal ganglia calcification (Disease Ontology:DOID:0060230)", "pathway": " (sce:YIL047C)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "11875433;14562106;15665377;16847258;17330950;18407956;19684113;19779198;21126336;21177495;23749301;24374639;32597660;33481703;33491328;7592711;9169870", "class_list": "", "function": "Inorganic ion transporter that mediates phosphate ion export across the plasma membrane (By similarity). Has been implicated in the regulation of G protein-coupled signal transduction (PubMed:7592711)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 27, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VVN4;P40964", "ec_number_list": [], "go_molecular_function": "GO:0005315 phosphate transmembrane transporter activity;GO:0000822 inositol hexakisphosphate binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0006817 phosphate ion transport;GO:0016036 cellular response to phosphate starvation", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P40528-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40529-1", "uniprot_id": [ { "id": "AGE2_YEAST", "url": "https://www.uniprot.org/uniprot/P40529", "type": "external" } ], "mass": 32638.0, "length": 298, "protein_name": "ADP-ribosylation factor GTPase-activating protein effector protein 2", "gene_name": "AGE2", "organism": "Yeast", "refseq_name": "GTPase-activating protein AGE2", "refseq_ac": [ { "id": "NP_012220", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012220", "type": "external" } ], "gene_names_uniprotkb": "AGE2", "gene_names_refseq": "AGE2; SAT2", "protein_names_uniprotkb": "ADP-ribosylation factor GTPase-activating protein effector protein 2; ARF GAP effector protein 2", "protein_names_refseq": "GTPase-activating protein AGE2", "tax_id": 559292, "disease": "candidiasis (Disease Ontology:DOID:1508)", "pathway": " (sce:YIL044C)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "14562095;14562106;15665377;18407956;19779198;20702584;21126336;22814378;23749301;24374639;24909858;30516470;32597660;33229814;33481703;33491328;9169870", "class_list": "", "function": "GTPase-activating protein for the ADP ribosylation factor family., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 18, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 18, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 18, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 19, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 17, "binding_glycan_count": 0, "secondary_ac_list": "D6VVN8", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0000138 Golgi trans cisterna", "go_biological_process": "GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006891 intra-Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 3.7, "record_id": "P40529-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40531-1", "uniprot_id": [ { "id": "GVP36_YEAST", "url": "https://www.uniprot.org/uniprot/P40531", "type": "external" } ], "mass": 36670.0, "length": 326, "protein_name": "Protein GVP36", "gene_name": "GVP36", "organism": "Yeast", "refseq_name": "Gvp36p", "refseq_ac": [ { "id": "NP_012223", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012223", "type": "external" } ], "gene_names_uniprotkb": "GVP36", "gene_names_refseq": "GVP36", "protein_names_uniprotkb": "Protein GVP36; 36 kDa Golgi vesicle protein", "protein_names_refseq": "Gvp36p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL041W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "12872131;14562106;15665377;16107716;17330950;17563356;18407956;19779198;19795423;19823750;21126336;22106047;23749301;24374639;27821475;32597660;33481703;33491328;9169870", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 27, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVP1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006897 endocytosis;GO:0030950 establishment or maintenance of actin cytoskeleton polarity;GO:0007033 vacuole organization", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P40531-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40532-1", "uniprot_id": [ { "id": "APQ12_YEAST", "url": "https://www.uniprot.org/uniprot/P40532", "type": "external" } ], "mass": 16508.0, "length": 138, "protein_name": "Nuclear membrane organization protein APQ12", "gene_name": "APQ12", "organism": "Yeast", "refseq_name": "Apq12p", "refseq_ac": [ { "id": "NP_012224", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012224", "type": "external" } ], "gene_names_uniprotkb": "APQ12", "gene_names_refseq": "APQ12", "protein_names_uniprotkb": "Nuclear membrane organization protein APQ12", "protein_names_refseq": "Apq12p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL040W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;15273328;16847258;17724120;20016074;24374639;9169870", "class_list": "", "function": "Involved in the regulation of lipid homeostasis in the endoplasmic reticulum, thereby impacting nuclear pore complex biogenesis and localization, and nucleocytoplasmic mRNA transport., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVP2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0031965 nuclear membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0055088 lipid homeostasis;GO:0006998 nuclear envelope organization;GO:0051028 mRNA transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P40532-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40533-1", "uniprot_id": [ { "id": "TED1_YEAST", "url": "https://www.uniprot.org/uniprot/P40533", "type": "external" } ], "mass": 54928.0, "length": 473, "protein_name": "Protein TED1", "gene_name": "TED1", "organism": "Yeast", "refseq_name": "Ted1p", "refseq_ac": [ { "id": "NP_012225", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012225", "type": "external" } ], "gene_names_uniprotkb": "TED1", "gene_names_refseq": "TED1", "protein_names_uniprotkb": "Protein TED1; Trafficking of EMP24/ERV25-dependent cargo disrupted protein 1", "protein_names_refseq": "Ted1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL039W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;14562106;17989219;19756047;24374639;9169870", "class_list": "", "function": "Acts together with EMP24 and ERV25 in cargo exit from the endoplasmic reticulum., [UniProtKB, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VVP3", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006506 GPI anchor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P40533-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40537-1", "uniprot_id": [ { "id": "ULP2_YEAST", "url": "https://www.uniprot.org/uniprot/P40537", "type": "external" } ], "mass": 116883.0, "length": 1034, "protein_name": "Ubiquitin-like-specific protease 2", "gene_name": "ULP2", "organism": "Yeast", "refseq_name": "SUMO protease ULP2", "refseq_ac": [ { "id": "NP_012233", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012233", "type": "external" } ], "gene_names_uniprotkb": "ULP2; SMT4", "gene_names_refseq": "SMT4; ULP2", "protein_names_uniprotkb": "Ubiquitin-like-specific protease 2; 3.4.22.-", "protein_names_refseq": "SUMO protease ULP2", "tax_id": 559292, "disease": "acute promyelocytic leukemia (Disease Ontology:DOID:0060318)", "pathway": " (sce:YIL031W); (R-SCE-3065679); (R-SCE-6791226)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "14562106;17563356;18407956;19779198;20702584;23749301;24374639;32597660;33481703;33491328;9169870", "class_list": "", "function": "Insertion mutation in SMT4 confers temperature and benomyl sensitivity; high copy suppressor of a temperature sensitive mutation in MIF2., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 34, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVQ0", "ec_number_list": [ { "id": "3.4.22.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.-", "type": "external" }, { "id": "3.4.22.68", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.68", "type": "external" }, { "id": "2.7.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.-", "type": "external" } ], "go_molecular_function": "GO:0016929 deSUMOylase activity;GO:0008234 cysteine-type peptidase activity;GO:0003711 transcription elongation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0006508 proteolysis;GO:0007094 mitotic spindle assembly checkpoint signaling;GO:0030261 chromosome condensation;GO:0016926 protein desumoylation;GO:0006276 plasmid maintenance", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P40537-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40544-1", "uniprot_id": [ { "id": "YKE4_YEAST", "url": "https://www.uniprot.org/uniprot/P40544", "type": "external" } ], "mass": 37418.0, "length": 346, "protein_name": "Zinc transporter YKE4", "gene_name": "YKE4", "organism": "Yeast", "refseq_name": "Zn(2+) transporter YKE4", "refseq_ac": [ { "id": "NP_012241", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012241", "type": "external" } ], "gene_names_uniprotkb": "YKE4", "gene_names_refseq": "YKE4", "protein_names_uniprotkb": "Zinc transporter YKE4", "protein_names_refseq": "Zn(2+) transporter YKE4", "tax_id": 559292, "disease": "alcohol-associated liver disease (Disease Ontology:DOID:0070658); Ehlers-Danlos syndrome spondylodysplastic type 3 (Disease Ontology:DOID:0080739); agammaglobulinemia 9 (Disease Ontology:DOID:0081141); Ehlers-Danlos syndrome (Disease Ontology:DOID:13359)", "pathway": " (sce:YIL023C); (R-SCE-442380)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "16760462;16847258;24374639;9169870", "class_list": "", "function": "Zinc transporter whose role depends on the zinc status of the cells. It helps to balance zinc levels between the cytosol and the secretory pathway. It transports zinc into the secretory pathway in a zinc-adequate environment and in a high zinc medium. In high zinc medium, transport of zinc into the secretory pathway is a way to eliminate zinc from the cytosol. Under low cytosolic zinc conditions, it removes zinc from the secretory pathway and acts as a zinc importer that helps to alleviate ER stress., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VVQ6", "ec_number_list": [], "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0071577 zinc ion transmembrane transport;GO:0006829 zinc ion transport;GO:0006882 intracellular zinc ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P40544-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40545-1", "uniprot_id": [ { "id": "HIS4_YEAST", "url": "https://www.uniprot.org/uniprot/P40545", "type": "external" } ], "mass": 29557.0, "length": 261, "protein_name": "1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase", "gene_name": "HIS6", "organism": "Yeast", "refseq_name": "1-(5-phosphoribosyl)-5- ((5-phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase HIS6", "refseq_ac": [ { "id": "NP_012244", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012244", "type": "external" } ], "gene_names_uniprotkb": "HIS6", "gene_names_refseq": "HIS6", "protein_names_uniprotkb": "1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; 5-proFAR isomerase; 5.3.1.16; Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase", "protein_names_refseq": "1-(5-phosphoribosyl)-5- ((5-phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase HIS6", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL020C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;16731983;17322287;24374639;33491328;9169870;9332345", "class_list": "", "function": "Catalyzes the isomerization of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVQ9;Q6Q5P5", "ec_number_list": [ { "id": "5.3.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.16", "type": "external" } ], "go_molecular_function": "GO:0003949 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000105 L-histidine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P40545-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40546-1", "uniprot_id": [ { "id": "FAF1_YEAST", "url": "https://www.uniprot.org/uniprot/P40546", "type": "external" } ], "mass": 38889.0, "length": 346, "protein_name": "Protein FAF1", "gene_name": "FAF1", "organism": "Yeast", "refseq_name": "Faf1p", "refseq_ac": [ { "id": "NP_012245", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012245", "type": "external" } ], "gene_names_uniprotkb": "FAF1", "gene_names_refseq": "FAF1", "protein_names_uniprotkb": "Protein FAF1; Forty S assembly factor", "protein_names_refseq": "Faf1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL019W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "15178413;17322287;22814378;24374639;33481703;9169870", "class_list": "", "function": "Required for pre-rRNA processing and 40S ribosomal subunit assembly. Seems to act in the processing of 35S rRNA at the A(0), A(1), and A(2) cleavage sites., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVR0;Q6Q5G5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P40546-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40549-1", "uniprot_id": [ { "id": "MNT3_YEAST", "url": "https://www.uniprot.org/uniprot/P40549", "type": "external" } ], "mass": 72410.0, "length": 630, "protein_name": "Alpha-1,3-mannosyltransferase MNT3", "gene_name": "MNT3", "organism": "Yeast", "refseq_name": "alpha-1,3-mannosyltransferase MNT3", "refseq_ac": [ { "id": "NP_012251", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012251", "type": "external" } ], "gene_names_uniprotkb": "MNT3", "gene_names_refseq": "MNT3", "protein_names_uniprotkb": "Alpha-1,3-mannosyltransferase MNT3; 2.4.1.-", "protein_names_refseq": "alpha-1,3-mannosyltransferase MNT3", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL014W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10521541;14562106;17322287;22814378;24374639;9169870", "class_list": "glycogene;glycosyltransferase", "function": "Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VVR6", "ec_number_list": [], "go_molecular_function": "GO:0000033 alpha-1,3-mannosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0006493 protein O-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P40549-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40550-1", "uniprot_id": [ { "id": "PDR11_YEAST", "url": "https://www.uniprot.org/uniprot/P40550", "type": "external" } ], "mass": 160538.0, "length": 1411, "protein_name": "ATP-dependent permease PDR11", "gene_name": "PDR11", "organism": "Yeast", "refseq_name": "ATP-binding cassette multidrug transporter PDR11", "refseq_ac": [ { "id": "NP_012252", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012252", "type": "external" } ], "gene_names_uniprotkb": "PDR11", "gene_names_refseq": "PDR11", "protein_names_uniprotkb": "ATP-dependent permease PDR11", "protein_names_refseq": "ATP-binding cassette multidrug transporter PDR11", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL013C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12077145;16847258;24374639;7629127;9169870", "class_list": "", "function": "Transporter involved in the uptake of sterol., [UniProtKB, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6VVR7;Q03092", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0035376 sterol import", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P40550-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40552-1", "uniprot_id": [ { "id": "TIR3_YEAST", "url": "https://www.uniprot.org/uniprot/P40552", "type": "external" } ], "mass": 26308.0, "length": 269, "protein_name": "Cell wall protein TIR3", "gene_name": "TIR3", "organism": "Yeast", "refseq_name": "Tir3p", "refseq_ac": [ { "id": "NP_012254", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012254", "type": "external" } ], "gene_names_uniprotkb": "TIR3; YIB1", "gene_names_refseq": "TIR3; YIB1", "protein_names_uniprotkb": "Cell wall protein TIR3; TIP1-related protein 3", "protein_names_refseq": "Tir3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL011W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10383953;11292809;24374639;9169870", "class_list": "", "function": "Component of the cell wall. Required for anaerobic growth., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VVR8", "ec_number_list": [], "go_molecular_function": "GO:0005199 structural constituent of cell wall", "go_cellular_component": "GO:0071944 cell periphery;GO:0000324 fungal-type vacuole;GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P40552-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40566-1", "uniprot_id": [ { "id": "EGH1_YEAST", "url": "https://www.uniprot.org/uniprot/P40566", "type": "external" } ], "mass": 86979.0, "length": 764, "protein_name": "Ergosteryl-beta-glucosidase", "gene_name": "EGH1", "organism": "Yeast", "refseq_name": "hydrolase", "refseq_ac": [ { "id": "NP_012272", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012272", "type": "external" } ], "gene_names_uniprotkb": "EGH1; YIB7W", "gene_names_refseq": "EGH1", "protein_names_uniprotkb": "Ergosteryl-beta-glucosidase; 3.2.1.-", "protein_names_refseq": "hydrolase", "tax_id": 559292, "disease": "", "pathway": " (sce:YIR007W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562106;18407956;19779198;23749301;24374639;26116408;32597660;33481703;33491328;34965436;7762303;9169870", "class_list": "glycogene;glycosylhydrolase", "function": "Ergosteryl beta-glucosidase involved in the ergosteryl beta-glucoside (EG) catabolic pathway and vacuole formation via hydrolysis of EG to generate glucose (PubMed:26116408). Is also able to hydrolyze cholesteryl beta-glucoside and sitosteryl beta-glucoside to generate glucose; and C6-7-nitro-2,1,3-benzoxadiazole (NBD)-GlcCer to generate C6-NBD-ceramide (Cer) (PubMed:26116408)., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VVT7", "ec_number_list": [ { "id": "3.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.-", "type": "external" } ], "go_molecular_function": "GO:0050295 steryl-beta-glucosidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0000272 polysaccharide catabolic process;GO:1904462 ergosteryl 3-beta-D-glucoside catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P40566-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.10100", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40567-1", "uniprot_id": [ { "id": "MSL1_YEAST", "url": "https://www.uniprot.org/uniprot/P40567", "type": "external" } ], "mass": 12830.0, "length": 111, "protein_name": "U2 small nuclear ribonucleoprotein B''", "gene_name": "MSL1", "organism": "Yeast", "refseq_name": "U2 snRNP complex subunit MSL1", "refseq_ac": [ { "id": "NP_012274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012274", "type": "external" } ], "gene_names_uniprotkb": "MSL1; YIB9W", "gene_names_refseq": "MSL1; YIB9", "protein_names_uniprotkb": "U2 small nuclear ribonucleoprotein B''; U2 snRNP B''", "protein_names_refseq": "U2 snRNP complex subunit MSL1", "tax_id": 559292, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); disease of cellular proliferation (Disease Ontology:DOID:14566); germ cell cancer (Disease Ontology:DOID:2994); connective tissue disease (Disease Ontology:DOID:65)", "pathway": " (sce:YIR009W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11884590;14562106;17322287;24374639;7762303;8649387;9169870;9799242", "class_list": "", "function": "Involved in pre-mRNA splicing. This protein is associated with snRNP U2. It binds stem loop IV of U2 snRNA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVT9", "ec_number_list": [], "go_molecular_function": "GO:0030620 U2 snRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0071004 U2-type prespliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:1903241 U2-type prespliceosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P40567-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40570-1", "uniprot_id": [ { "id": "VLD1_YEAST", "url": "https://www.uniprot.org/uniprot/P40570", "type": "external" } ], "mass": 27600.0, "length": 242, "protein_name": "Vacuole localized DSC protein 1", "gene_name": "VLD1", "organism": "Yeast", "refseq_name": "Vld1p", "refseq_ac": [ { "id": "NP_012279", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012279", "type": "external" } ], "gene_names_uniprotkb": "VLD1", "gene_names_refseq": "VLD1", "protein_names_uniprotkb": "Vacuole localized DSC protein 1", "protein_names_refseq": "Vld1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIR014W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12748633;17322287;24374639;29355480;33481703;33491328;9169870", "class_list": "", "function": "Component of the vacuole-localized DSC E3 ubiquitin ligase complex involved in the targeting of the complex to the vacuole membrane via the AP3 pathway to ubiquitinate vacuolar membrane proteins (PubMed:29355480). Competes with GLD1 to determine the subcellular localizations of the DSC complex (PubMed:29355480)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVU4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0000329 fungal-type vacuole membrane;GO:0000324 fungal-type vacuole;GO:0044695 Dsc E3 ubiquitin ligase complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P40570-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40574-1", "uniprot_id": [ { "id": "YAP5_YEAST", "url": "https://www.uniprot.org/uniprot/P40574", "type": "external" } ], "mass": 28386.0, "length": 245, "protein_name": "AP-1-like transcription factor YAP5", "gene_name": "YAP5", "organism": "Yeast", "refseq_name": "Yap5p", "refseq_ac": [ { "id": "NP_012283", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012283", "type": "external" } ], "gene_names_uniprotkb": "YAP5", "gene_names_refseq": "YAP5", "protein_names_uniprotkb": "AP-1-like transcription factor YAP5", "protein_names_refseq": "Yap5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIR018W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "12464632;14555958;14562095;14562106;17322287;24374639;33481703;33491328;8665859;9169870;9372930", "class_list": "", "function": "Transcription activator involved in the regulation of genes expressed in response to environmental changes and metabolic requirements. According to genome-wide promoter binding and gene expression studies it is a coregulator for the expression of ribosomal genes, while its own expression is induced by the cell cycle specific activator SBF (SWI4-SWI6)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVU8", "ec_number_list": [], "go_molecular_function": "GO:0000976 transcription cis-regulatory region binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0071281 cellular response to iron ion", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P40574-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40578-1", "uniprot_id": [ { "id": "MGA2_YEAST", "url": "https://www.uniprot.org/uniprot/P40578", "type": "external" } ], "mass": 127055.0, "length": 1113, "protein_name": "Protein MGA2", "gene_name": "MGA2", "organism": "Yeast", "refseq_name": "Mga2p", "refseq_ac": [ { "id": "NP_012299", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012299", "type": "external" } ], "gene_names_uniprotkb": "MGA2", "gene_names_refseq": "MGA2", "protein_names_uniprotkb": "Protein MGA2", "protein_names_refseq": "Mga2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIR033W); (R-SCE-8948751)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "14562106;15665377;18407956;19779198;20702584;23749301;24374639;32597660;33481703;33491328;9169870", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVW4", "ec_number_list": [], "go_molecular_function": "GO:0106254 lipid sensor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0048255 mRNA stabilization;GO:0071456 cellular response to hypoxia;GO:0071279 cellular response to cobalt ion;GO:2001280 positive regulation of unsaturated fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P40578-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40580-1", "uniprot_id": [ { "id": "BZRD_YEAST", "url": "https://www.uniprot.org/uniprot/P40580", "type": "external" } ], "mass": 28804.0, "length": 263, "protein_name": "Benzil reductase ((S)-benzoin forming) IRC24", "gene_name": "IRC24", "organism": "Yeast", "refseq_name": "sepiapterin reductase family protein IRC24", "refseq_ac": [ { "id": "NP_012302", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012302", "type": "external" } ], "gene_names_uniprotkb": "IRC24", "gene_names_refseq": "IRC24", "protein_names_uniprotkb": "Benzil reductase ((S)-benzoin forming) IRC24; 1.1.1.320; Increased recombination centers protein 24", "protein_names_refseq": "sepiapterin reductase family protein IRC24", "tax_id": 559292, "disease": "cortisone reductase deficiency (Disease Ontology:DOID:0090139); cortisone reductase deficiency 2 (Disease Ontology:DOID:0090140); pre-eclampsia (Disease Ontology:DOID:10591); hypertension (Disease Ontology:DOID:10763); essential hypertension (Disease Ontology:DOID:10825); coronary artery disease (Disease Ontology:DOID:3393); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YIR036C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "11796169;14562095;14562106;17163986;17322287;18085829;22814378;24374639;32597660;33481703;33491328;37602278;9169870", "class_list": "", "function": "Reduces benzil stereospecifically to (S)-benzoin (PubMed:11796169, PubMed:37602278). Also reduces 1-phenyl-1,2-propanedione to 2-hydroxy-1-phenyl-1-propanone (PubMed:11796169). Is probably involved in a pathway contributing to genomic integrity (Probable)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVW7;Q54AB5", "ec_number_list": [ { "id": "1.1.1.320", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.320", "type": "external" } ], "go_molecular_function": "GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P40580-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40582-1", "uniprot_id": [ { "id": "GST1_YEAST", "url": "https://www.uniprot.org/uniprot/P40582", "type": "external" } ], "mass": 26795.0, "length": 234, "protein_name": "Glutathione S-transferase 1", "gene_name": "GTT1", "organism": "Yeast", "refseq_name": "bifunctional glutathione transferase/peroxidase", "refseq_ac": [ { "id": "NP_012304", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012304", "type": "external" } ], "gene_names_uniprotkb": "GTT1", "gene_names_refseq": "GTT1", "protein_names_uniprotkb": "Glutathione S-transferase 1; 2.5.1.18; GST-I", "protein_names_refseq": "bifunctional glutathione transferase/peroxidase", "tax_id": 559292, "disease": "", "pathway": " (sce:YIR038C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "18407956;19779198;23749301;24374639;33481703;33491328;9169870;9792709", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVW9", "ec_number_list": [ { "id": "1.11.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.9", "type": "external" }, { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" }, { "id": "1.8.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.5.1", "type": "external" } ], "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0004602 glutathione peroxidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane", "go_biological_process": "GO:0006749 glutathione metabolic process;GO:0010731 protein glutathionylation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P40582-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40583-1", "uniprot_id": [ { "id": "YPS6_YEAST", "url": "https://www.uniprot.org/uniprot/P40583", "type": "external" } ], "mass": 58214.0, "length": 537, "protein_name": "Aspartic proteinase yapsin-6", "gene_name": "YPS6", "organism": "Yeast", "refseq_name": "aspartyl protease", "refseq_ac": [ { "id": "NP_012305", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012305", "type": "external" } ], "gene_names_uniprotkb": "YPS6", "gene_names_refseq": "YPS6", "protein_names_uniprotkb": "Aspartic proteinase yapsin-6; 3.4.23.-", "protein_names_refseq": "aspartyl protease", "tax_id": 559292, "disease": "", "pathway": " (sce:YIR039C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10383953;16087741;19756047;24374639;9169870", "class_list": "", "function": "Cleaves proteins C-terminally to mono- and paired-basic residues (By similarity). Required for cell wall integrity., [UniProtKB, PubMed]", "predicted_glycosites": 12, "predicted_n_glycosites": 11, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 12, "binding_glycan_count": 0, "secondary_ac_list": "D6VVX0;E9PAD7", "ec_number_list": [], "go_molecular_function": "GO:0004190 aspartic-type endopeptidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0016485 protein processing;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P40583-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40858-1", "uniprot_id": [ { "id": "RN49_YEAST", "url": "https://www.uniprot.org/uniprot/P40858", "type": "external" } ], "mass": 18387.0, "length": 161, "protein_name": "Large ribosomal subunit protein bL21m", "gene_name": "MRPL49", "organism": "Yeast", "refseq_name": "mitochondrial 54S ribosomal protein bL21m MRPL49", "refseq_ac": [ { "id": "NP_012439", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012439", "type": "external" } ], "gene_names_uniprotkb": "MRPL49; J0904", "gene_names_refseq": "MRPL49; bL21m", "protein_names_uniprotkb": "Large ribosomal subunit protein bL21m; 54S ribosomal protein L49, mitochondrial; YmL49", "protein_names_refseq": "mitochondrial 54S ribosomal protein bL21m MRPL49", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL096W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "12392552;12748633;12775844;14562095;14562106;14576278;17322287;19779198;23749301;24374639;24675956;25609543;33491328;7871887;8641269;9151978", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW88", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P40858-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40884-1", "uniprot_id": [ { "id": "IMA5_YEAST", "url": "https://www.uniprot.org/uniprot/P40884", "type": "external" } ], "mass": 67557.0, "length": 581, "protein_name": "Oligo-1,6-glucosidase IMA5", "gene_name": "IMA5", "organism": "Yeast", "refseq_name": "oligo-1,6-glucosidase IMA5", "refseq_ac": [ { "id": "NP_012319", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012319", "type": "external" } ], "gene_names_uniprotkb": "IMA5; HRF581; J0228", "gene_names_refseq": "IMA5", "protein_names_uniprotkb": "Oligo-1,6-glucosidase IMA5; 3.2.1.10; Alpha-glucosidase; Isomaltase 5", "protein_names_refseq": "oligo-1,6-glucosidase IMA5", "tax_id": 559292, "disease": "cystinuria (Disease Ontology:DOID:9266)", "pathway": " (sce:YJL216C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12529331;20562106;24374639;7725802;8641269", "class_list": "glycogene;glycosylhydrolase", "function": "Alpha-glucosidase with specificity for isomaltose, maltose, and palatinose., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVY0", "ec_number_list": [], "go_molecular_function": "GO:0004558 alpha-1,4-glucosidase activity;GO:0004556 alpha-amylase activity;GO:0004574 oligo-1,6-glucosidase activity;GO:0004575 sucrose alpha-glucosidase activity;GO:0033934 glucan 1,4-alpha-maltotriohydrolase activity", "go_cellular_component": "", "go_biological_process": "GO:0000025 maltose catabolic process;GO:0005987 sucrose catabolic process;GO:0046352 disaccharide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P40884-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.10100", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40885-1", "uniprot_id": [ { "id": "HXT9_YEAST", "url": "https://www.uniprot.org/uniprot/P40885", "type": "external" } ], "mass": 62858.0, "length": 567, "protein_name": "Hexose transporter HXT9", "gene_name": "HXT9", "organism": "Yeast", "refseq_name": "hexose transporter HXT9", "refseq_ac": [ { "id": "NP_012316", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012316", "type": "external" } ], "gene_names_uniprotkb": "HXT9; HRC567; J0222", "gene_names_refseq": "HXT9", "protein_names_uniprotkb": "Hexose transporter HXT9", "protein_names_refseq": "hexose transporter HXT9", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL219W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "16847258;24374639;7725802;8641269", "class_list": "", "function": "Probable glucose transporter., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VVX7", "ec_number_list": [], "go_molecular_function": "GO:0005353 fructose transmembrane transporter activity;GO:0015578 mannose transmembrane transporter activity;GO:0005351 carbohydrate:proton symporter activity;GO:0055056 D-glucose transmembrane transporter activity;GO:0005354 galactose transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0008643 carbohydrate transport;GO:0008645 hexose transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P40885-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40886-1", "uniprot_id": [ { "id": "HXT8_YEAST", "url": "https://www.uniprot.org/uniprot/P40886", "type": "external" } ], "mass": 63493.0, "length": 569, "protein_name": "Hexose transporter HXT8", "gene_name": "HXT8", "organism": "Yeast", "refseq_name": "hexose transporter HXT8", "refseq_ac": [ { "id": "NP_012321", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012321", "type": "external" } ], "gene_names_uniprotkb": "HXT8; HRA569; J0232", "gene_names_refseq": "HXT8", "protein_names_uniprotkb": "Hexose transporter HXT8", "protein_names_refseq": "hexose transporter HXT8", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL214W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;16847258;24374639;7725802;8641269", "class_list": "", "function": "Probable glucose transporter., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VVY1", "ec_number_list": [], "go_molecular_function": "GO:0005353 fructose transmembrane transporter activity;GO:0015578 mannose transmembrane transporter activity;GO:0005351 carbohydrate:proton symporter activity;GO:0055056 D-glucose transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0008643 carbohydrate transport;GO:0008645 hexose transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P40886-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40889-1", "uniprot_id": [ { "id": "YJW5_YEAST", "url": "https://www.uniprot.org/uniprot/P40889", "type": "external" } ], "mass": 197565.0, "length": 1758, "protein_name": "Y' element ATP-dependent helicase YJL225C", "gene_name": "HRD1054; HRD732; J0202", "organism": "Yeast", "refseq_name": "Y' element ATP-dependent helicase", "refseq_ac": [ { "id": "NP_012311", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012311", "type": "external" } ], "gene_names_uniprotkb": "HRD1054; HRD732; J0202", "gene_names_refseq": "", "protein_names_uniprotkb": "Y' element ATP-dependent helicase YJL225C; 5.6.2.-", "protein_names_refseq": "Y' element ATP-dependent helicase", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL225C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "24374639;7725802;8641269;9837911", "class_list": "", "function": "Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVX3;P40887;Q05371;Q9UQW2", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003676 nucleic acid binding;GO:0004386 helicase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0000722 telomere maintenance via recombination", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P40889-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40890-1", "uniprot_id": [ { "id": "VTH2_YEAST", "url": "https://www.uniprot.org/uniprot/P40890", "type": "external" } ], "mass": 174402.0, "length": 1549, "protein_name": "VPS10 homolog 2", "gene_name": "VTH2", "organism": "Yeast", "refseq_name": "signal sequence-binding protein", "refseq_ac": [ { "id": "NP_012313", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012313", "type": "external" } ], "gene_names_uniprotkb": "VTH2; HRC1549; J0213", "gene_names_refseq": "VTH2", "protein_names_uniprotkb": "VPS10 homolog 2; Sortilin VTH2", "protein_names_refseq": "signal sequence-binding protein", "tax_id": 559292, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); proteinuria (Disease Ontology:DOID:576); abdominal aortic aneurysm (Disease Ontology:DOID:7693)", "pathway": " (sce:YJL222W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;24374639;33481703;7725802;8636229;8641269;8662642", "class_list": "", "function": "Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VVX5", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0000166 nucleotide binding;GO:0005048 signal sequence binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0016020 membrane;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0006895 Golgi to endosome transport;GO:0006623 protein targeting to vacuole;GO:0006896 Golgi to vacuole transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P40890-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40897-1", "uniprot_id": [ { "id": "OPT1_YEAST", "url": "https://www.uniprot.org/uniprot/P40897", "type": "external" } ], "mass": 91616.0, "length": 799, "protein_name": "Oligopeptide transporter 1", "gene_name": "OPT1", "organism": "Yeast", "refseq_name": "oligopeptide transporter OPT1", "refseq_ac": [ { "id": "NP_012323", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012323", "type": "external" } ], "gene_names_uniprotkb": "OPT1; GSH11; HGT1; HRD799; J0236", "gene_names_refseq": "DUG4; GSH11; HGT1; OPT1", "protein_names_uniprotkb": "Oligopeptide transporter 1; High affinity glutathione transporter 1", "protein_names_refseq": "oligopeptide transporter OPT1", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL212C)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10652283;10788431;14562106;16847258;18407956;19684113;19779198;19795423;19823750;24374639;32597660;33481703;33491328;7725802;8641269", "class_list": "", "function": "High affinity transporter for glutathione. Also transports tetra- and pentapeptides like the opioids leucine enkephalin (Tyr-Gly-Gly-Phe-Leu) and methionine enkephalin (Tyr-Gly-Gly_Phe-Met) across the cell membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VVY3", "ec_number_list": [], "go_molecular_function": "GO:0035673 oligopeptide transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0015031 protein transport;GO:0006857 oligopeptide transport", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P40897-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000011001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40965-1", "uniprot_id": [ { "id": "MSH4_YEAST", "url": "https://www.uniprot.org/uniprot/P40965", "type": "external" } ], "mass": 99225.0, "length": 878, "protein_name": "MutS protein homolog 4", "gene_name": "MSH4", "organism": "Yeast", "refseq_name": "MutS family protein MSH4", "refseq_ac": [ { "id": "NP_116652", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116652", "type": "external" } ], "gene_names_uniprotkb": "MSH4", "gene_names_refseq": "MSH4", "protein_names_uniprotkb": "MutS protein homolog 4", "protein_names_refseq": "MutS family protein MSH4", "tax_id": 559292, "disease": "spermatogenic failure 2 (Disease Ontology:DOID:0070164); primary ovarian insufficiency (Disease Ontology:DOID:5426)", "pathway": " (sce:YFL003C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "22031224;24374639;7670463;8001134;8789262;9374523", "class_list": "", "function": "Involved in meiotic recombination. Facilitate crossovers between homologs during meiosis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTM6", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0030983 mismatched DNA binding;GO:0140664 ATP-dependent DNA damage sensor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000228 nuclear chromosome;GO:0062128 MutSgamma complex", "go_biological_process": "GO:0007131 reciprocal meiotic recombination", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P40965-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40971-1", "uniprot_id": [ { "id": "LYS14_YEAST", "url": "https://www.uniprot.org/uniprot/P40971", "type": "external" } ], "mass": 89397.0, "length": 790, "protein_name": "Lysine biosynthesis regulatory protein LYS14", "gene_name": "LYS14", "organism": "Yeast", "refseq_name": "Lys14p", "refseq_ac": [ { "id": "NP_010317", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010317", "type": "external" } ], "gene_names_uniprotkb": "LYS14; YD9673.04C", "gene_names_refseq": "LYS14", "protein_names_uniprotkb": "Lysine biosynthesis regulatory protein LYS14", "protein_names_refseq": "Lys14p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR034C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562106;17322287;18407956;19779198;22814378;23749301;24374639;32597660;33491328;7935367;9169867", "class_list": "", "function": "Activates the transcription of lysine biosynthesis genes. This activation is dependent on the inducer alpha-aminoadipate semialdehyde and repressed by lysine., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS18", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0009085 lysine biosynthetic process;GO:2001196 positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P40971-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40975-1", "uniprot_id": [ { "id": "PMP2_YEAST", "url": "https://www.uniprot.org/uniprot/P40975", "type": "external" } ], "mass": 4848.0, "length": 43, "protein_name": "Plasma membrane ATPase proteolipid 2", "gene_name": "PMP2", "organism": "Yeast", "refseq_name": "proteolipid ATPase", "refseq_ac": [ { "id": "NP_010898", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010898", "type": "external" } ], "gene_names_uniprotkb": "PMP2; YEL017BC", "gene_names_refseq": "PMP2", "protein_names_uniprotkb": "Plasma membrane ATPase proteolipid 2", "protein_names_refseq": "proteolipid ATPase", "tax_id": 559292, "disease": "", "pathway": " (sce:YEL017C-A)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;17322287;24374639;8063750;9169868", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLN2", "ec_number_list": [], "go_molecular_function": "GO:0030234 enzyme regulator activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0071944 cell periphery;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0032781 positive regulation of ATP-dependent activity", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P40975-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40985-1", "uniprot_id": [ { "id": "HUL4_YEAST", "url": "https://www.uniprot.org/uniprot/P40985", "type": "external" } ], "mass": 103457.0, "length": 892, "protein_name": "Probable E3 ubiquitin-protein ligase HUL4", "gene_name": "HUL4", "organism": "Yeast", "refseq_name": "putative E3 ubiquitin-protein ligase HUL4", "refseq_ac": [ { "id": "NP_012570", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012570", "type": "external" } ], "gene_names_uniprotkb": "HUL4; J1608", "gene_names_refseq": "HUL4", "protein_names_uniprotkb": "Probable E3 ubiquitin-protein ligase HUL4; 2.3.2.26; HECT ubiquitin ligase 4; HECT-type E3 ubiquitin transferase HUL4", "protein_names_refseq": "putative E3 ubiquitin-protein ligase HUL4", "tax_id": 559292, "disease": "Angelman syndrome (Disease Ontology:DOID:1932)", "pathway": " (sce:YJR036C); (R-SCE-983168)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "15828860;24374639;7668047;7957102;8641269;9858558", "class_list": "", "function": "Probable E3 ubiquitin-protein ligase, component of the TRAMP (TRF4) complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism limiting inappropriate expression of genetic information. Polyadenylation is required for the degradative activity of the exosome on several of its nuclear RNA substrates., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWK9", "ec_number_list": [ { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "6.2.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.45", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "1.14.11.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.27", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "6.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.2.-", "type": "external" } ], "go_molecular_function": "GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0031499 TRAMP complex;GO:0005628 prospore membrane", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0000209 protein polyubiquitination;GO:0000292 RNA fragment catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P40985-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40986-1", "uniprot_id": [ { "id": "CDC1_YEAST", "url": "https://www.uniprot.org/uniprot/P40986", "type": "external" } ], "mass": 57147.0, "length": 491, "protein_name": "Cell division control protein 1", "gene_name": "CDC1", "organism": "Yeast", "refseq_name": "putative lipid phosphatase CDC1", "refseq_ac": [ { "id": "NP_010468", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010468", "type": "external" } ], "gene_names_uniprotkb": "CDC1; DSR1; ESP2; YD9395.16", "gene_names_refseq": "CDC1; DSC1; DSR1; ESP2", "protein_names_uniprotkb": "Cell division control protein 1; 3.1.-.-", "protein_names_refseq": "putative lipid phosphatase CDC1", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR182W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562106;16847258;18407956;19684113;21177495;24374639;32597660;33481703;33491328;7969142;9169867", "class_list": "", "function": "Probable metallophosphoesterase which may participate in recombinational repair of double -strand breaks., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSG5", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0006281 DNA repair;GO:0051301 cell division;GO:0006506 GPI anchor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P40986-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40987-1", "uniprot_id": [ { "id": "CIN1_YEAST", "url": "https://www.uniprot.org/uniprot/P40987", "type": "external" } ], "mass": 116648.0, "length": 1014, "protein_name": "Chromosome instability protein 1", "gene_name": "CIN1", "organism": "Yeast", "refseq_name": "Cin1p", "refseq_ac": [ { "id": "NP_014994", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014994", "type": "external" } ], "gene_names_uniprotkb": "CIN1; O6350", "gene_names_refseq": "CIN1", "protein_names_uniprotkb": "Chromosome instability protein 1", "protein_names_refseq": "Cin1p", "tax_id": 559292, "disease": "early onset progressive encephalopathy with brain atrophy and thin corpus callosum (Disease Ontology:DOID:0070423)", "pathway": " (sce:YOR349W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;21126336;24374639;8948102;9169874", "class_list": "", "function": "Required for microtubule stability. Interacts with CIN4., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W344", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0048487 beta-tubulin binding", "go_cellular_component": "", "go_biological_process": "GO:0006457 protein folding;GO:0000226 microtubule cytoskeleton organization;GO:0007021 tubulin complex assembly;GO:0007023 post-chaperonin tubulin folding pathway", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P40987-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P40990-1", "uniprot_id": [ { "id": "MSS2_YEAST", "url": "https://www.uniprot.org/uniprot/P40990", "type": "external" } ], "mass": 41476.0, "length": 351, "protein_name": "Protein MSS2, mitochondrial", "gene_name": "MSS2", "organism": "Yeast", "refseq_name": "Mss2p", "refseq_ac": [ { "id": "NP_010176", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010176", "type": "external" } ], "gene_names_uniprotkb": "MSS2; D2340", "gene_names_refseq": "MSS2", "protein_names_uniprotkb": "Protein MSS2, mitochondrial", "protein_names_refseq": "Mss2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL107W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11604502;11950926;14562106;24374639;7857963;8896274;9169867", "class_list": "", "function": "Required to stabilize mitochondrial cytochrome C oxidase subunit 2 (COX2) and to translocate the C-terminal domain of COX2 through the inner membrane., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRP3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0032979 protein insertion into mitochondrial inner membrane from matrix", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P40990-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41057-1", "uniprot_id": [ { "id": "RS29A_YEAST", "url": "https://www.uniprot.org/uniprot/P41057", "type": "external" } ], "mass": 6661.0, "length": 56, "protein_name": "Small ribosomal subunit protein uS14A", "gene_name": "RPS29A", "organism": "Yeast", "refseq_name": "40S ribosomal protein uS14 RPS29A", "refseq_ac": [ { "id": "NP_013492", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013492", "type": "external" } ], "gene_names_uniprotkb": "RPS29A; L8084.11; RPS36A; YS29A", "gene_names_refseq": "RPS29A", "protein_names_uniprotkb": "Small ribosomal subunit protein uS14A; 40S ribosomal protein S29-A; S36; YS29", "protein_names_refseq": "40S ribosomal protein uS14 RPS29A", "tax_id": 559292, "disease": "Diamond-Blackfan anemia 13 (Disease Ontology:DOID:0111889)", "pathway": " (sce:YLR388W); (R-SCE-156827); (R-SCE-1799339); (R-SCE-6791226); (R-SCE-72649); (R-SCE-72689); (R-SCE-72695); (R-SCE-72702); (R-SCE-72706); (R-SCE-975956); (R-SCE-975957); (R-SCE-9954714)", "pathway_count": 12, "publication_count": 19, "publication_id_list": "10601260;14562095;14562106;17244705;17287358;18407956;18782943;19779198;21109664;22096102;23749301;24374639;24524803;32597660;33481703;33491328;34965436;9169871;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A2TBM8;D6VZ23;P05761", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation;GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P41057-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41058-1", "uniprot_id": [ { "id": "RS29B_YEAST", "url": "https://www.uniprot.org/uniprot/P41058", "type": "external" } ], "mass": 6728.0, "length": 56, "protein_name": "Small ribosomal subunit protein uS14B", "gene_name": "RPS29B", "organism": "Yeast", "refseq_name": "40S ribosomal protein uS14 RPS29B", "refseq_ac": [ { "id": "NP_010222", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010222", "type": "external" } ], "gene_names_uniprotkb": "RPS29B; RPS36B; YS29B", "gene_names_refseq": "RPS29B", "protein_names_uniprotkb": "Small ribosomal subunit protein uS14B; 40S ribosomal protein S29-B; S36; YS29", "protein_names_refseq": "40S ribosomal protein uS14 RPS29B", "tax_id": 559292, "disease": "Diamond-Blackfan anemia 13 (Disease Ontology:DOID:0111889)", "pathway": " (sce:YDL061C)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10601260;11701127;14562095;14562106;14976550;17244705;18782943;19779198;22096102;23749301;24374639;24524803;32597660;33481703;33491328;9169867;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A2TBP5;D6VRT5;P05761", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation;GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P41058-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41544-1", "uniprot_id": [ { "id": "SYS1_YEAST", "url": "https://www.uniprot.org/uniprot/P41544", "type": "external" } ], "mass": 23716.0, "length": 203, "protein_name": "Protein SYS1", "gene_name": "SYS1", "organism": "Yeast", "refseq_name": "Sys1p", "refseq_ac": [ { "id": "NP_012530", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012530", "type": "external" } ], "gene_names_uniprotkb": "SYS1; J1402; YJR83.17", "gene_names_refseq": "SYS1", "protein_names_uniprotkb": "Protein SYS1", "protein_names_refseq": "Sys1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL004C); (R-SCE-6811440)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "14557538;14562106;15077113;15077114;16847258;17322287;18407956;21126336;24374639;3327602;33491328;7720878;8641269", "class_list": "", "function": "Necessary for the targeting of ARL3 to the Golgi. Involved in protein trafficking. May serve as a receptor for acetylated ARL3., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWH1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005829 cytosol;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0043001 Golgi to plasma membrane protein transport;GO:0006895 Golgi to endosome transport;GO:0034067 protein localization to Golgi apparatus", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P41544-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41696-1", "uniprot_id": [ { "id": "AZF1_YEAST", "url": "https://www.uniprot.org/uniprot/P41696", "type": "external" } ], "mass": 101170.0, "length": 914, "protein_name": "Transcription factor AZF1", "gene_name": "AZF1", "organism": "Yeast", "refseq_name": "Azf1p", "refseq_ac": [ { "id": "NP_014756", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014756", "type": "external" } ], "gene_names_uniprotkb": "AZF1; O3244; YOR3244W", "gene_names_refseq": "AZF1", "protein_names_uniprotkb": "Transcription factor AZF1; asparagine-rich zinc-finger protein 1", "protein_names_refseq": "Azf1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR113W)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "11839825;14562106;16467472;19684113;19779198;21177495;22218487;22932476;23388641;23549479;23749301;24374639;27693355;33229814;33491328;34019539;7975891;8904341;9169874;9200815;9799362", "class_list": "", "function": "As an intrinsically disordered protein, AZF1 is capable of forming the prion [AZF1+] that confers resistance to the drug radicicol in a gain-of-function manner but decreases the expression of AZF1's target genes., [UniProtKB, PubMed, PubMed]; Transcription factor involved in the diauxic shift (PubMed:11839825, PubMed:16467472, PubMed:23549479). In the presence of glucose, activates carbon and energy metabolism genes, and in te presence of glycerol-lactate, activates genes needed for cell wall maintenance (PubMed:11839825, PubMed:16467472, PubMed:23549479). Binds to DNA elements with the sequence AAAAGAAA (A4GA3), a motif enriched in the promoters of AZF1-sensitive genes (PubMed:16467472, PubMed:23388641). Required for glucose induction of CLN3 transcription (PubMed:11839825). Also required for proper FLO11 expression (PubMed:23388641). May also function as a corepressor (PubMed:34019539)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 13, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 13, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 13, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 13, "binding_glycan_count": 0, "secondary_ac_list": "D6W2H2", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0043565 sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0071322 cellular response to carbohydrate stimulus;GO:0060237 regulation of fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 3.6, "record_id": "P41696-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41698-1", "uniprot_id": [ { "id": "BUD8_YEAST", "url": "https://www.uniprot.org/uniprot/P41698", "type": "external" } ], "mass": 66289.0, "length": 603, "protein_name": "Bud site selection protein 8", "gene_name": "BUD8", "organism": "Yeast", "refseq_name": "Bud8p", "refseq_ac": [ { "id": "NP_013457", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013457", "type": "external" } ], "gene_names_uniprotkb": "BUD8; L9638.3", "gene_names_refseq": "BUD8", "protein_names_uniprotkb": "Bud site selection protein 8", "protein_names_refseq": "Bud8p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR353W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "11514631;15356260;17287358;18407956;19779198;20678480;21625000;23749301;24374639;32597660;33481703;33491328;9169871", "class_list": "", "function": "Involved in positioning the distal bud pole signal., [UniProtKB, PubMed]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 31, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D6VYZ1;Q06482", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0000131 incipient cellular bud site;GO:0005934 cellular bud tip", "go_biological_process": "GO:0000282 cellular bud site selection;GO:0007124 pseudohyphal growth", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P41698-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41733-1", "uniprot_id": [ { "id": "CDC91_YEAST", "url": "https://www.uniprot.org/uniprot/P41733", "type": "external" } ], "mass": 44741.0, "length": 394, "protein_name": "GPI transamidase component GAB1", "gene_name": "GAB1", "organism": "Yeast", "refseq_name": "GPI-anchor transamidase subunit GAB1", "refseq_ac": [ { "id": "NP_013564", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013564", "type": "external" } ], "gene_names_uniprotkb": "GAB1; CDC91; L9122.2", "gene_names_refseq": "CDC91; GAB1", "protein_names_uniprotkb": "GPI transamidase component GAB1; Cell division control protein 91", "protein_names_refseq": "GPI-anchor transamidase subunit GAB1", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR459W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12802054;16847258;24374639;9169871", "class_list": "", "function": "Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ92", "ec_number_list": [], "go_molecular_function": "GO:0003923 GPI-anchor transamidase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0042765 GPI-anchor transamidase complex", "go_biological_process": "GO:0051301 cell division;GO:0006506 GPI anchor biosynthetic process;GO:0016255 attachment of GPI anchor to protein;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P41733-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41806-1", "uniprot_id": [ { "id": "VMA21_YEAST", "url": "https://www.uniprot.org/uniprot/P41806", "type": "external" } ], "mass": 8435.0, "length": 77, "protein_name": "Vacuolar ATPase assembly integral membrane protein VMA21", "gene_name": "VMA21", "organism": "Yeast", "refseq_name": "Vma21p", "refseq_ac": [ { "id": "NP_011619", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011619", "type": "external" } ], "gene_names_uniprotkb": "VMA21", "gene_names_refseq": "VMA21", "protein_names_uniprotkb": "Vacuolar ATPase assembly integral membrane protein VMA21", "protein_names_refseq": "Vma21p", "tax_id": 559292, "disease": "X-linked myopathy with excessive autophagy (Disease Ontology:DOID:0050760); follicular lymphoma (Disease Ontology:DOID:0050873)", "pathway": " (sce:YGR105W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562106;15356264;16569636;16847258;16926153;17077122;17322287;18799613;24374639;7841520;8416931;9169869", "class_list": "", "function": "Functions with VOA1 in assembly of the integral membrane sector (also called V0 sector) of the V-ATPase in the endoplasmic reticulum. Escorts the assembled V0 sector in COPII vesicles. Also required for normal packaging of the SNARE BOS1 and possibly the ER to Golgi transport receptor ERV29., [UniProtKB, PubMed, PubMed, HAMAP, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUN7;Q6Q5Q3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0012507 ER to Golgi transport vesicle membrane;GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane", "go_biological_process": "GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P41806-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41815-1", "uniprot_id": [ { "id": "BAP3_YEAST", "url": "https://www.uniprot.org/uniprot/P41815", "type": "external" } ], "mass": 67365.0, "length": 604, "protein_name": "Valine amino-acid permease", "gene_name": "BAP3", "organism": "Yeast", "refseq_name": "amino acid transporter BAP3", "refseq_ac": [ { "id": "NP_010331", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010331", "type": "external" } ], "gene_names_uniprotkb": "BAP3; PAP1; YD9609.02C", "gene_names_refseq": "BAP3; PAP1", "protein_names_uniprotkb": "Valine amino-acid permease; Branched-chain amino-acid permease 3", "protein_names_refseq": "amino acid transporter BAP3", "tax_id": 559292, "disease": "retinitis pigmentosa 68 (Disease Ontology:DOID:0110374); sensorineural hearing loss (Disease Ontology:DOID:10003); blindness (Disease Ontology:DOID:1432)", "pathway": " (sce:YDR046C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10467005;10654085;16847258;23749301;24374639;33481703;33491328;8200527;9169867", "class_list": "", "function": "Involved in transport of isoleucine, leucine, valine, cysteine, methionine, phenylalanine, tyrosine and tryptophan., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS34", "ec_number_list": [], "go_molecular_function": "GO:0015171 amino acid transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0055085 transmembrane transport;GO:0006865 amino acid transport;GO:0003333 amino acid transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P41815-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41817-1", "uniprot_id": [ { "id": "CUP9_YEAST", "url": "https://www.uniprot.org/uniprot/P41817", "type": "external" } ], "mass": 34654.0, "length": 306, "protein_name": "Homeobox protein CUP9", "gene_name": "CUP9", "organism": "Yeast", "refseq_name": "Cup9p", "refseq_ac": [ { "id": "NP_015148", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015148", "type": "external" } ], "gene_names_uniprotkb": "CUP9", "gene_names_refseq": "CUP9", "protein_names_uniprotkb": "Homeobox protein CUP9", "protein_names_refseq": "Cup9p", "tax_id": 559292, "disease": "restless legs syndrome (Disease Ontology:DOID:0050425); acute promyelocytic leukemia (Disease Ontology:DOID:0060318); leukemia (Disease Ontology:DOID:1240); acute leukemia (Disease Ontology:DOID:12603); Down syndrome (Disease Ontology:DOID:14250); cancer (Disease Ontology:DOID:162); brain infarction (Disease Ontology:DOID:3454); muscular atrophy (Disease Ontology:DOID:767); chronic myeloid leukemia (Disease Ontology:DOID:8552); myeloid leukemia (Disease Ontology:DOID:8692); acute lymphoblastic leukemia (Disease Ontology:DOID:9952); substance dependence (Disease Ontology:DOID:9973)", "pathway": " (sce:YPL177C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;17322287;22814378;24374639;33491328;7969120;9169875", "class_list": "", "function": "Probable DNA-binding protein which plays a role in protecting yeast cells against copper toxicity. May regulate the expression of important copper homeostatic genes., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W3J1", "ec_number_list": [], "go_molecular_function": "GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0043565 sequence-specific DNA binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:2000877 negative regulation of oligopeptide transport;GO:2000879 negative regulation of dipeptide transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P41817-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41819-1", "uniprot_id": [ { "id": "DIM1_YEAST", "url": "https://www.uniprot.org/uniprot/P41819", "type": "external" } ], "mass": 35951.0, "length": 318, "protein_name": "Dimethyladenosine transferase", "gene_name": "DIM1", "organism": "Yeast", "refseq_name": "putative dimethyladenosine transferase", "refseq_ac": [ { "id": "NP_015057", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015057", "type": "external" } ], "gene_names_uniprotkb": "DIM1", "gene_names_refseq": "CDH1; DIM1", "protein_names_uniprotkb": "Dimethyladenosine transferase; 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase; 18S rRNA dimethylase; 2.1.1.183; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase", "protein_names_refseq": "putative dimethyladenosine transferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL266W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "12628929;19779198;24374639;29897761;31227701;32597660;32943521;33229814;33326748;33491328;8064863;9169875", "class_list": "", "function": "Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6W3A4", "ec_number_list": [ { "id": "2.1.1.183", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.183", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0052909 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity;GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0030688 preribosome, small subunit precursor;GO:0030686 90S preribosome", "go_biological_process": "GO:0031167 rRNA methylation;GO:0000154 rRNA modification;GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P41819-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41913-1", "uniprot_id": [ { "id": "GLDS1_YEAST", "url": "https://www.uniprot.org/uniprot/P41913", "type": "external" } ], "mass": 57048.0, "length": 522, "protein_name": "Protein GDS1", "gene_name": "GDS1", "organism": "Yeast", "refseq_name": "Gds1p", "refseq_ac": [ { "id": "NP_015000", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015000", "type": "external" } ], "gene_names_uniprotkb": "GDS1", "gene_names_refseq": "GDS1", "protein_names_uniprotkb": "Protein GDS1", "protein_names_refseq": "Gds1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR355W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562106;19684113;19795423;19823750;23749301;24374639;32597660;33481703;33491328;8750239;9169874", "class_list": "", "function": "Involved in nuclear control of mitochondria., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 17, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W350", "ec_number_list": [], "go_molecular_function": "GO:0062060 NuA4 histone acetyltransferase complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0009060 aerobic respiration", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P41913-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41930-1", "uniprot_id": [ { "id": "SSU1_YEAST", "url": "https://www.uniprot.org/uniprot/P41930", "type": "external" } ], "mass": 52545.0, "length": 458, "protein_name": "Sulfite efflux pump SSU1", "gene_name": "SSU1", "organism": "Yeast", "refseq_name": "Ssu1p", "refseq_ac": [ { "id": "NP_015233", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015233", "type": "external" } ], "gene_names_uniprotkb": "SSU1; LPG16W", "gene_names_refseq": "LPG16; SSU1", "protein_names_uniprotkb": "Sulfite efflux pump SSU1; Sulfite sensitivity protein SSU1", "protein_names_refseq": "Ssu1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL092W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10870099;12368245;16847258;16879422;17322287;17563356;18407956;19779198;20702584;23749301;24374639;32597660;33491328;8082198;9169875;9294463", "class_list": "", "function": "Involved in efflux of free sulfite. Mutations in the SSU1 gene cause sensitivity to sulfite., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3S5;P87026;Q02893;Q2VQ61;Q2VQ65;Q2VQ70;Q2VQ74;Q2VQ76;Q2VQ77;Q8J1R0;Q8J1R1", "ec_number_list": [], "go_molecular_function": "GO:0000319 sulfite transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0000316 sulfite transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P41930-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P41940-1", "uniprot_id": [ { "id": "MPG1_YEAST", "url": "https://www.uniprot.org/uniprot/P41940", "type": "external" } ], "mass": 39566.0, "length": 361, "protein_name": "Mannose-1-phosphate guanyltransferase", "gene_name": "PSA1", "organism": "Yeast", "refseq_name": "mannose-1-phosphate guanylyltransferase", "refseq_ac": [ { "id": "NP_010228", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010228", "type": "external" } ], "gene_names_uniprotkb": "PSA1; MPG1; SRB1; VIG9", "gene_names_refseq": "MPG1; PSA1; SRB1; VIG9", "protein_names_uniprotkb": "Mannose-1-phosphate guanyltransferase; 2.7.7.13; ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase", "protein_names_refseq": "mannose-1-phosphate guanylyltransferase", "tax_id": 559292, "disease": "autosomal recessive limb-girdle muscular dystrophy type 2T (Disease Ontology:DOID:0110294); congenital muscular dystrophy-dystroglycanopathy type A14 (Disease Ontology:DOID:0111233); muscular dystrophy-dystroglycanopathy (Disease Ontology:DOID:0112374); muscular dystrophy-dystroglycanopathy type B14 (Disease Ontology:DOID:0112377)", "pathway": " (sce:YDL055C)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "11055399;14562106;18407956;19779198;19795423;19823750;20702584;22106047;22814378;23749301;24374639;32597660;33481703;33491328;8821656;9169867;9195935", "class_list": "", "function": "Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRU1", "ec_number_list": [ { "id": "2.7.7.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.13", "type": "external" } ], "go_molecular_function": "GO:0004475 mannose-1-phosphate guanylyltransferase (GTP) activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0000032 cell wall mannoprotein biosynthetic process;GO:0009101 glycoprotein biosynthetic process;GO:0009298 GDP-mannose biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P41940-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42222-1", "uniprot_id": [ { "id": "ERR3_YEAST", "url": "https://www.uniprot.org/uniprot/P42222", "type": "external" } ], "mass": 47313.0, "length": 437, "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "organism": "Yeast", "refseq_name": "phosphopyruvate hydratase ERR3", "refseq_ac": [ { "id": "NP_014056", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014056", "type": "external" } ], "gene_names_uniprotkb": "ERR3; YM9924.15", "gene_names_refseq": "ERR3", "protein_names_uniprotkb": "Enolase-related protein 3; 2-phospho-D-glycerate hydro-lyase; 2-phosphoglycerate dehydratase; 4.2.1.11", "protein_names_refseq": "phosphopyruvate hydratase ERR3", "tax_id": 559292, "disease": "prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); urinary bladder cancer (Disease Ontology:DOID:11054); migraine without aura (Disease Ontology:DOID:12783); aortic valve stenosis (Disease Ontology:DOID:1712); neuroendocrine carcinoma (Disease Ontology:DOID:1800); breast carcinoma (Disease Ontology:DOID:3459); brain disease (Disease Ontology:DOID:936)", "pathway": " (sce:YMR323W); (R-SCE-70171); (R-SCE-70263)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "24374639;9169872", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0F0", "ec_number_list": [ { "id": "4.2.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.11", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004634 phosphopyruvate hydratase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000015 phosphopyruvate hydratase complex", "go_biological_process": "GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P42222-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42223-1", "uniprot_id": [ { "id": "SBE2_YEAST", "url": "https://www.uniprot.org/uniprot/P42223", "type": "external" } ], "mass": 98971.0, "length": 864, "protein_name": "Protein SBE2", "gene_name": "SBE2", "organism": "Yeast", "refseq_name": "Sbe2p", "refseq_ac": [ { "id": "NP_010638", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010638", "type": "external" } ], "gene_names_uniprotkb": "SBE2; D9476.7", "gene_names_refseq": "SBE2", "protein_names_uniprotkb": "Protein SBE2; Suppressor of BEM4 protein 2", "protein_names_refseq": "Sbe2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR351W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10679005;12045225;17287358;18407956;19684113;19779198;19795423;19823750;21126336;21177495;23749301;24374639;30516470;32597660;33481703;33491328;9169867", "class_list": "", "function": "With SBE22, is involved in cell wall integrity and polarity processes like bud growth, through the transport of CHS3 and UTR2 to sites of growth., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 36, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSY1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus", "go_biological_process": "GO:0015031 protein transport;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P42223-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42826-1", "uniprot_id": [ { "id": "XKS1_YEAST", "url": "https://www.uniprot.org/uniprot/P42826", "type": "external" } ], "mass": 68321.0, "length": 600, "protein_name": "Xylulose kinase", "gene_name": "XKS1", "organism": "Yeast", "refseq_name": "xylulokinase", "refseq_ac": [ { "id": "NP_011710", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011710", "type": "external" } ], "gene_names_uniprotkb": "XKS1; G7584", "gene_names_refseq": "XKS1", "protein_names_uniprotkb": "Xylulose kinase; 2.7.1.17; Xylulokinase", "protein_names_refseq": "xylulokinase", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR194C); (R-SCE-5661270)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "14562095;14562106;19779198;19795423;19823750;21126336;24374639;33481703;33491328;7645350;9169869;9595677", "class_list": "", "function": "Xylulose kinase necessary for growth in culture media with D-xylulose as the solecarbon source., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUX6", "ec_number_list": [ { "id": "2.7.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.17", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004856 D-xylulokinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0005997 xylulose metabolic process;GO:0042732 D-xylose metabolic process;GO:0005998 xylulose catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P42826-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42833-1", "uniprot_id": [ { "id": "HXT14_YEAST", "url": "https://www.uniprot.org/uniprot/P42833", "type": "external" } ], "mass": 60979.0, "length": 540, "protein_name": "Hexose transporter HXT14", "gene_name": "HXT14", "organism": "Yeast", "refseq_name": "Hxt14p", "refseq_ac": [ { "id": "NP_014081", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014081", "type": "external" } ], "gene_names_uniprotkb": "HXT14; HXT9; N0345", "gene_names_refseq": "HXT14", "protein_names_uniprotkb": "Hexose transporter HXT14", "protein_names_refseq": "Hxt14p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL318C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "16847258;24374639;7502583;9169873", "class_list": "", "function": "Probable glucose transporter., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0M7", "ec_number_list": [], "go_molecular_function": "GO:0005351 carbohydrate:proton symporter activity;GO:0005354 galactose transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0008643 carbohydrate transport;GO:0008645 hexose transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P42833-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42834-1", "uniprot_id": [ { "id": "MDJ2_YEAST", "url": "https://www.uniprot.org/uniprot/P42834", "type": "external" } ], "mass": 16474.0, "length": 146, "protein_name": "Mitochondrial DnaJ homolog 2", "gene_name": "MDJ2", "organism": "Yeast", "refseq_name": "Mdj2p", "refseq_ac": [ { "id": "NP_014071", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014071", "type": "external" } ], "gene_names_uniprotkb": "MDJ2; N0315", "gene_names_refseq": "MDJ2", "protein_names_uniprotkb": "Mitochondrial DnaJ homolog 2", "protein_names_refseq": "Mdj2p", "tax_id": 559292, "disease": "3-methylglutaconic aciduria type 5 (Disease Ontology:DOID:0110000)", "pathway": " (sce:YNL328C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;16027163;17322287;24374639;7645347;9169873;9325105", "class_list": "", "function": "Plays a role in mitochondrial biogenesis and protein folding. Participates in the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner, probably by stimulating activity of mtHSP70 (SSC1)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0L9", "ec_number_list": [], "go_molecular_function": "GO:0001671 ATPase activator activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0001405 PAM complex, Tim23 associated import motor", "go_biological_process": "GO:0030150 protein import into mitochondrial matrix", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P42834-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42841-1", "uniprot_id": [ { "id": "PFS2_YEAST", "url": "https://www.uniprot.org/uniprot/P42841", "type": "external" } ], "mass": 53143.0, "length": 465, "protein_name": "Polyadenylation factor subunit 2", "gene_name": "PFS2", "organism": "Yeast", "refseq_name": "cleavage polyadenylation factor subunit PFS2", "refseq_ac": [ { "id": "NP_014082", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014082", "type": "external" } ], "gene_names_uniprotkb": "PFS2; N0348", "gene_names_refseq": "PFS2", "protein_names_uniprotkb": "Polyadenylation factor subunit 2", "protein_names_refseq": "cleavage polyadenylation factor subunit PFS2", "tax_id": 559292, "disease": "primary ovarian insufficiency (Disease Ontology:DOID:5426)", "pathway": " (sce:YNL317W); (R-SCE-77595)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "10619842;12819204;14562095;14562106;17322287;24374639;33491328;7502583;9169873", "class_list": "", "function": "Integral and essential component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. May bridge the CPF and CFIA complexes., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0M8;Q6B1M2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005847 mRNA cleavage and polyadenylation specificity factor complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0031124 mRNA 3'-end processing;GO:0030846 termination of RNA polymerase II transcription, poly(A)-coupled", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P42841-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42842-1", "uniprot_id": [ { "id": "EMW1_YEAST", "url": "https://www.uniprot.org/uniprot/P42842", "type": "external" } ], "mass": 102336.0, "length": 904, "protein_name": "Essential for maintenance of the cell wall protein 1", "gene_name": "EMW1", "organism": "Yeast", "refseq_name": "tetratricopeptide repeat-containing protein EMW1", "refseq_ac": [ { "id": "NP_014086", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014086", "type": "external" } ], "gene_names_uniprotkb": "EMW1; N0364", "gene_names_refseq": "EMW1", "protein_names_uniprotkb": "Essential for maintenance of the cell wall protein 1", "protein_names_refseq": "tetratricopeptide repeat-containing protein EMW1", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL313C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "11206552;14562095;14562106;14690591;21273246;24374639;33491328;7502583;9169873", "class_list": "", "function": "Required for the maintenance of the cell wall integrity., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W0N2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P42842-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42847-1", "uniprot_id": [ { "id": "RT18_YEAST", "url": "https://www.uniprot.org/uniprot/P42847", "type": "external" } ], "mass": 24563.0, "length": 217, "protein_name": "Small ribosomal subunit protein uS11m", "gene_name": "MRPS18", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein uS11m MRPS18", "refseq_ac": [ { "id": "NP_014093", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014093", "type": "external" } ], "gene_names_uniprotkb": "MRPS18; N0397", "gene_names_refseq": "MRPS18; uS11m", "protein_names_uniprotkb": "Small ribosomal subunit protein uS11m; 37S ribosomal protein S18, mitochondrial; YmS18", "protein_names_refseq": "mitochondrial 37S ribosomal protein uS11m MRPS18", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL306W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "12392552;14562095;14562106;14576278;17322287;24374639;25609543;28154081;32597660;33491328;7502583;8553702;9151978;9169873", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0N9", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006412 translation;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P42847-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42883-1", "uniprot_id": [ { "id": "THI12_YEAST", "url": "https://www.uniprot.org/uniprot/P42883", "type": "external" } ], "mass": 38620.0, "length": 340, "protein_name": "4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI12", "gene_name": "THI12", "organism": "Yeast", "refseq_name": "4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase", "refseq_ac": [ { "id": "NP_014067", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014067", "type": "external" } ], "gene_names_uniprotkb": "THI12; N0295", "gene_names_refseq": "THI12", "protein_names_uniprotkb": "4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI12; 2.-.-.-; HMP-P synthase; Hydroxymethylpyrimidine phosphate synthase; Thiamine biosynthesis protein 12; Thiamine pyrimidine synthase", "protein_names_refseq": "4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL332W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12777485;24374639;8533474;9169873", "class_list": "", "function": "Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP). The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0L5", "ec_number_list": [ { "id": "2.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.-.-.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0106344 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP", "go_cellular_component": "", "go_biological_process": "GO:0009229 thiamine diphosphate biosynthetic process;GO:0009228 thiamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P42883-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42934-1", "uniprot_id": [ { "id": "PMT6_YEAST", "url": "https://www.uniprot.org/uniprot/P42934", "type": "external" } ], "mass": 88026.0, "length": 759, "protein_name": "Dolichyl-phosphate-mannose--protein mannosyltransferase 6", "gene_name": "PMT6", "organism": "Yeast", "refseq_name": "dolichyl-phosphate-mannose-protein mannosyltransferase PMT6", "refseq_ac": [ { "id": "NP_011715", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011715", "type": "external" } ], "gene_names_uniprotkb": "PMT6; G7722", "gene_names_refseq": "PMT6", "protein_names_uniprotkb": "Dolichyl-phosphate-mannose--protein mannosyltransferase 6; 2.4.1.109", "protein_names_refseq": "dolichyl-phosphate-mannose-protein mannosyltransferase PMT6", "tax_id": 559292, "disease": "lissencephaly (Disease Ontology:DOID:0050453); Walker-Warburg syndrome (Disease Ontology:DOID:0050560); autosomal recessive limb-girdle muscular dystrophy (Disease Ontology:DOID:0110274); autosomal recessive limb-girdle muscular dystrophy type 2N (Disease Ontology:DOID:0110298); congenital muscular dystrophy-dystroglycanopathy type A2 (Disease Ontology:DOID:0111240); muscular dystrophy-dystroglycanopathy (Disease Ontology:DOID:0112374); muscular dystrophy-dystroglycanopathy type B2 (Disease Ontology:DOID:0112380); muscular dystrophy (Disease Ontology:DOID:9884)", "pathway": " (sce:YGR199W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "16847258;18182384;18407956;22814378;23749301;24374639;33481703;33491328;8904340;9169869;9184828", "class_list": "glycogene;glycosyltransferase", "function": "Protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity. Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins., [UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VUY1", "ec_number_list": [ { "id": "2.4.1.109", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.109", "type": "external" } ], "go_molecular_function": "GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006493 protein O-linked glycosylation;GO:0035269 protein O-linked glycosylation via mannose", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P42934-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000010001.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42937-1", "uniprot_id": [ { "id": "YCH1_YEAST", "url": "https://www.uniprot.org/uniprot/P42937", "type": "external" } ], "mass": 17249.0, "length": 148, "protein_name": "CDC25-like phosphatase YCH1", "gene_name": "YCH1", "organism": "Yeast", "refseq_name": "phosphatase YCH1", "refseq_ac": [ { "id": "NP_011719", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011719", "type": "external" } ], "gene_names_uniprotkb": "YCH1; G7731", "gene_names_refseq": "YCH1", "protein_names_uniprotkb": "CDC25-like phosphatase YCH1; 3.1.3.-; CDC25 homolog 1", "protein_names_refseq": "phosphatase YCH1", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR203W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10818363;14562095;14562106;17322287;19382206;22814378;24374639;8904340;9169869;9733650", "class_list": "", "function": "Protein phosphatase., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUY5", "ec_number_list": [], "go_molecular_function": "GO:0016791 phosphatase activity;GO:0004725 protein tyrosine phosphatase activity;GO:0004792 thiosulfate-cyanide sulfurtransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0016311 dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P42937-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42938-1", "uniprot_id": [ { "id": "TDA10_YEAST", "url": "https://www.uniprot.org/uniprot/P42938", "type": "external" } ], "mass": 33337.0, "length": 290, "protein_name": "Probable ATP-dependent kinase TDA10", "gene_name": "TDA10", "organism": "Yeast", "refseq_name": "putative ATP-dependent kinase", "refseq_ac": [ { "id": "NP_011721", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011721", "type": "external" } ], "gene_names_uniprotkb": "TDA10; G7737", "gene_names_refseq": "TDA10", "protein_names_uniprotkb": "Probable ATP-dependent kinase TDA10; 2.7.-.-; Topoisomerase I damage affected protein 10", "protein_names_refseq": "putative ATP-dependent kinase", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR205W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;14562106;14997573;17322287;21173034;24374639;33491328;3514599;8904340;9169869", "class_list": "", "function": "ATP-dependent kinase whose specificity is not yet known., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUY8", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016301 kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P42938-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42940-1", "uniprot_id": [ { "id": "ETFB_YEAST", "url": "https://www.uniprot.org/uniprot/P42940", "type": "external" } ], "mass": 28759.0, "length": 261, "protein_name": "Electron transfer flavoprotein subunit beta", "gene_name": "CIR1", "organism": "Yeast", "refseq_name": "Cir1p", "refseq_ac": [ { "id": "NP_011723", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011723", "type": "external" } ], "gene_names_uniprotkb": "CIR1; G7742", "gene_names_refseq": "CIR1", "protein_names_uniprotkb": "Electron transfer flavoprotein subunit beta; Beta-ETF; Changed intracellular redox state protein 1", "protein_names_refseq": "Cir1p", "tax_id": 559292, "disease": "multiple acyl-CoA dehydrogenase deficiency (Disease Ontology:DOID:0060358)", "pathway": " (sce:YGR207C); (R-SCE-611105)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "14562095;14562106;15961414;17322287;21253464;22814378;24374639;33491328;8904340;9169869", "class_list": "", "function": "Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase. Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism. ETFB binds an AMP molecule that probably has a purely structural role., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUZ0", "ec_number_list": [], "go_molecular_function": "GO:0009055 electron transfer activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P42940-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42941-1", "uniprot_id": [ { "id": "SERB_YEAST", "url": "https://www.uniprot.org/uniprot/P42941", "type": "external" } ], "mass": 34207.0, "length": 309, "protein_name": "Phosphoserine phosphatase", "gene_name": "SER2", "organism": "Yeast", "refseq_name": "phosphoserine phosphatase", "refseq_ac": [ { "id": "NP_011724", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011724", "type": "external" } ], "gene_names_uniprotkb": "SER2; G7744", "gene_names_refseq": "SER2", "protein_names_uniprotkb": "Phosphoserine phosphatase; 3.1.3.3; O-phosphoserine phosphohydrolase; PSPase; PSP", "protein_names_refseq": "phosphoserine phosphatase", "tax_id": 559292, "disease": "PSPH deficiency (Disease Ontology:DOID:0050724); alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (sce:YGR208W); (R-SCE-977347)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "14562106;20489023;24374639;8904340;9169869", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUZ1", "ec_number_list": [ { "id": "3.1.3.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.3", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0036424 L-phosphoserine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006564 L-serine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P42941-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42943-1", "uniprot_id": [ { "id": "TCPH_YEAST", "url": "https://www.uniprot.org/uniprot/P42943", "type": "external" } ], "mass": 59736.0, "length": 550, "protein_name": "T-complex protein 1 subunit eta", "gene_name": "CCT7", "organism": "Yeast", "refseq_name": "chaperonin-containing T-complex subunit CCT7", "refseq_ac": [ { "id": "NP_012424", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012424", "type": "external" } ], "gene_names_uniprotkb": "CCT7; J0804", "gene_names_refseq": "CCT7; TCP7", "protein_names_uniprotkb": "T-complex protein 1 subunit eta; CCT-eta; TCP-1-eta", "protein_names_refseq": "chaperonin-containing T-complex subunit CCT7", "tax_id": 559292, "disease": "intrinsic cardiomyopathy (Disease Ontology:DOID:0060036); sensory peripheral neuropathy (Disease Ontology:DOID:2491)", "pathway": " (sce:YJL111W); (R-SCE-390471); (R-SCE-6814122)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "19795423;19823750;24374639;33481703;33491328;7483851;8641269;8948101", "class_list": "", "function": "Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. In yeast may play a role in mitotic spindle formation (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW73", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity;GO:0140662 ATP-dependent protein folding chaperone", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005832 chaperonin-containing T-complex", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P42943-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42944-1", "uniprot_id": [ { "id": "GZF3_YEAST", "url": "https://www.uniprot.org/uniprot/P42944", "type": "external" } ], "mass": 60520.0, "length": 551, "protein_name": "Protein GZF3", "gene_name": "GZF3", "organism": "Yeast", "refseq_name": "Gzf3p", "refseq_ac": [ { "id": "NP_012425", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012425", "type": "external" } ], "gene_names_uniprotkb": "GZF3; J0806", "gene_names_refseq": "DEH1; GZF3; NIL2", "protein_names_uniprotkb": "Protein GZF3", "protein_names_refseq": "Gzf3p", "tax_id": 559292, "disease": "familial atrial fibrillation (Disease Ontology:DOID:0050650); atrioventricular septal defect (Disease Ontology:DOID:0050651); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); myelodysplastic syndrome (Disease Ontology:DOID:0050908); congenital nonspherocytic hemolytic anemia 9 (Disease Ontology:DOID:0051008); colitis (Disease Ontology:DOID:0060180); atrial fibrillation (Disease Ontology:DOID:0060224); hypoparathyroidism-retardation-dysmorphism syndrome (Disease Ontology:DOID:0060348); hypoparathyroidism-deafness-renal disease syndrome (Disease Ontology:DOID:0060878); transient myeloproliferative syndrome (Disease Ontology:DOID:0060888); bicuspid aortic valve disease (Disease Ontology:DOID:0080332); myeloid leukemia associated with Down Syndrome (Disease Ontology:DOID:0080798); atrial heart septal defect 2 (Disease Ontology:DOID:0110107); atrial heart septal defect 9 (Disease Ontology:DOID:0110114); pancreatic hypoplasia-diabetes-congenital heart disease syndrome (Disease Ontology:DOID:0111733); X-linked thrombocytopenia with beta-thalassemia (Disease Ontology:DOID:0111767); immunodeficiency 21 (Disease Ontology:DOID:0111947); X-linked dyserythropoietic anemia (Disease Ontology:DOID:0112156); sensorineural hearing loss (Disease Ontology:DOID:10003); pre-eclampsia (Disease Ontology:DOID:10591); hypertension (Disease Ontology:DOID:10763); essential hypertension (Disease Ontology:DOID:10825); hypoparathyroidism (Disease Ontology:DOID:11199); beta thalassemia (Disease Ontology:DOID:12241); aplastic anemia (Disease Ontology:DOID:12449); dilated cardiomyopathy (Disease Ontology:DOID:12930); lung cancer (Disease Ontology:DOID:1324); major depressive disorder (Disease Ontology:DOID:1470); thrombocytopenia (Disease Ontology:DOID:1588); depressive disorder (Disease Ontology:DOID:1596); ventricular septal defect (Disease Ontology:DOID:1657); congenital heart disease (Disease Ontology:DOID:1682); atrial heart septal defect (Disease Ontology:DOID:1882); colon adenocarcinoma (Disease Ontology:DOID:234); nephrosis (Disease Ontology:DOID:2527); asthma (Disease Ontology:DOID:2841); congenital diaphragmatic hernia (Disease Ontology:DOID:3827); clear cell renal cell carcinoma (Disease Ontology:DOID:4467); Klatskin's tumor (Disease Ontology:DOID:4927); myelofibrosis (Disease Ontology:DOID:4971); myocardial infarction (Disease Ontology:DOID:5844); tetralogy of Fallot (Disease Ontology:DOID:6419); pulmonary hypertension (Disease Ontology:DOID:6432); autoimmune thyroiditis (Disease Ontology:DOID:7188); polycythemia (Disease Ontology:DOID:8432); myeloid leukemia (Disease Ontology:DOID:8692); acute myeloid leukemia (Disease Ontology:DOID:9119); Barrett's esophagus (Disease Ontology:DOID:9206); colorectal cancer (Disease Ontology:DOID:9256); acute myocardial infarction (Disease Ontology:DOID:9408)", "pathway": " (sce:YJL110C); (R-SCE-9018519)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "14562106;18407956;19684113;19779198;21177495;23749301;24374639;32597660;33229814;33491328;7483851;8641269;8948101", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 9, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 9, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 9, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 16, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 50, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D6VW74", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051457 maintenance of protein location in nucleus;GO:0090295 nitrogen catabolite repression of transcription", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P42944-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P42950-1", "uniprot_id": [ { "id": "GSM1_YEAST", "url": "https://www.uniprot.org/uniprot/P42950", "type": "external" } ], "mass": 70382.0, "length": 618, "protein_name": "Glucose starvation modulator protein 1", "gene_name": "GSM1", "organism": "Yeast", "refseq_name": "Gsm1p", "refseq_ac": [ { "id": "NP_012432", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012432", "type": "external" } ], "gene_names_uniprotkb": "GSM1; 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Binds specifically to 5'-CGGN(8)CGG-3' and 5'-CGGN(9)CGG-3' sequences in the promoter region., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW81;Q66R68", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0009267 cellular response to starvation;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P42950-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43538-1", "uniprot_id": [ { "id": "YFG6_YEAST", "url": "https://www.uniprot.org/uniprot/P43538", "type": "external" } ], "mass": 43829.0, "length": 392, "protein_name": "Y' element ATP-dependent helicase YFL066C", "gene_name": "", "organism": "Yeast", "refseq_name": "Y' element ATP-dependent helicase", "refseq_ac": [ { "id": "NP_116589", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116589", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Y' element ATP-dependent helicase YFL066C; 5.6.2.-", "protein_names_refseq": "Y' element ATP-dependent helicase", "tax_id": 559292, "disease": "", "pathway": " (sce:YFL066C)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "24374639;7670463;9837911", "class_list": "", "function": "Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTG5", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003676 nucleic acid binding;GO:0004386 helicase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P43538-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43544-1", "uniprot_id": [ { "id": "SNO3_YEAST", "url": "https://www.uniprot.org/uniprot/P43544", "type": "external" } ], "mass": 25132.0, "length": 222, "protein_name": "Probable pyridoxal 5'-phosphate synthase subunit SNO3", "gene_name": "SNO3", "organism": "Yeast", "refseq_name": "putative pyridoxal 5'-phosphate synthase", "refseq_ac": [ { "id": "NP_116595", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116595", "type": "external" } ], "gene_names_uniprotkb": "SNO3", "gene_names_refseq": "SNO3", "protein_names_uniprotkb": "Probable pyridoxal 5'-phosphate synthase subunit SNO3; 3.5.1.2; 4.3.3.6; PDX2 homolog 3; Pdx2.3; Pyridoxal 5'-phosphate synthase glutaminase subunit", "protein_names_refseq": "putative pyridoxal 5'-phosphate synthase", "tax_id": 559292, "disease": "", "pathway": " (sce:YFL060C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12271461;14562106;24374639;7670463", "class_list": "", "function": "Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of a SNZ isoform., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTH0", "ec_number_list": [ { "id": "6.3.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.5.5", "type": "external" }, { "id": "6.3.4.16", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.16", "type": "external" }, { "id": "2.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.3.2", "type": "external" }, { "id": "3.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.2", "type": "external" }, { "id": "4.3.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:4.3.2.10", "type": "external" }, { "id": "4.3.3.6", "url": "https://www.rhea-db.org/rhea/?query=ec:4.3.3.6", "type": "external" } ], "go_molecular_function": "GO:0004359 glutaminase activity;GO:0036381 pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity", "go_cellular_component": "GO:0005829 cytosol;GO:1903600 glutaminase complex", "go_biological_process": "GO:0042823 pyridoxal phosphate biosynthetic process;GO:0008614 pyridoxine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P43544-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43545-1", "uniprot_id": [ { "id": "SNZ3_YEAST", "url": "https://www.uniprot.org/uniprot/P43545", "type": "external" } ], "mass": 32019.0, "length": 298, "protein_name": "Probable pyridoxal 5'-phosphate synthase subunit SNZ3", "gene_name": "SNZ3", "organism": "Yeast", "refseq_name": "pyridoxine biosynthesis protein SNZ3", "refseq_ac": [ { "id": "NP_116596", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116596", "type": "external" } ], "gene_names_uniprotkb": "SNZ3", "gene_names_refseq": "SNZ3", "protein_names_uniprotkb": "Probable pyridoxal 5'-phosphate synthase subunit SNZ3; 4.3.3.6; PDX1 homolog 3; PLP synthase subunit SNZ3; Pdx1.3", "protein_names_refseq": "pyridoxine biosynthesis protein SNZ3", "tax_id": 559292, "disease": "", "pathway": " (sce:YFL059W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12271461;19779198;24374639;7670463", "class_list": "", "function": "Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by a SNO isoform. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTH1", "ec_number_list": [ { "id": "3.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.2", "type": "external" }, { "id": "4.3.3.6", "url": "https://www.rhea-db.org/rhea/?query=ec:4.3.3.6", "type": "external" } ], "go_molecular_function": "GO:0016843 amine-lyase activity;GO:0036381 pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity", "go_cellular_component": "", "go_biological_process": "GO:0006520 amino acid metabolic process;GO:0008615 pyridoxine biosynthetic process;GO:0042823 pyridoxal phosphate biosynthetic process;GO:0009228 thiamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P43545-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43548-1", "uniprot_id": [ { "id": "AGP3_YEAST", "url": "https://www.uniprot.org/uniprot/P43548", "type": "external" } ], "mass": 61052.0, "length": 558, "protein_name": "General amino acid permease AGP3", "gene_name": "AGP3", "organism": "Yeast", "refseq_name": "Agp3p", "refseq_ac": [ { "id": "NP_116600", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116600", "type": "external" } ], "gene_names_uniprotkb": "AGP3", "gene_names_refseq": "AGP3", "protein_names_uniprotkb": "General amino acid permease AGP3", "protein_names_refseq": "Agp3p", "tax_id": 559292, "disease": "retinitis pigmentosa 68 (Disease Ontology:DOID:0110374)", "pathway": " (sce:YFL055W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "16847258;21177495;24374639;7670463", "class_list": "", "function": "General amino acid permease with broad substrate specificity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTH5", "ec_number_list": [], "go_molecular_function": "GO:0015171 amino acid transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0055085 transmembrane transport;GO:0006865 amino acid transport;GO:0003333 amino acid transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P43548-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43549-1", "uniprot_id": [ { "id": "AQY3_YEAST", "url": "https://www.uniprot.org/uniprot/P43549", "type": "external" } ], "mass": 70507.0, "length": 646, "protein_name": "Aquaglycerol porin AQY3", "gene_name": "AQY3", "organism": "Yeast", "refseq_name": "Aqy3p", "refseq_ac": [ { "id": "NP_116601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116601", "type": "external" } ], "gene_names_uniprotkb": "AQY3", "gene_names_refseq": "AQY3", "protein_names_uniprotkb": "Aquaglycerol porin AQY3; Aquaporin-3", "protein_names_refseq": "Aqy3p", "tax_id": 559292, "disease": "colitis (Disease Ontology:DOID:0060180); morbid obesity (Disease Ontology:DOID:11981); nephrogenic diabetes insipidus (Disease Ontology:DOID:12387); hypothyroidism (Disease Ontology:DOID:1459); brain ischemia (Disease Ontology:DOID:2316); brain edema (Disease Ontology:DOID:4724); ulcerative colitis (Disease Ontology:DOID:8577); Crohn's disease (Disease Ontology:DOID:8778); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (sce:YFL054C); (R-SCE-432030); (R-SCE-432040); (R-SCE-432047)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "12832087;16847258;17322287;18407956;19684113;19779198;21126336;24374639;33491328;7670463;9765289", "class_list": "", "function": "Channel protein that mediates glycerol entry under ethanol stimulation (PubMed:12832087). Does not seem to mediate glycerol uptake under standard conditions (PubMed:12832087)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTH6", "ec_number_list": [], "go_molecular_function": "GO:0015250 water channel activity;GO:0015254 glycerol channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0055085 transmembrane transport;GO:0006833 water transport;GO:0015793 glycerol transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P43549-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43550-1", "uniprot_id": [ { "id": "DAK2_YEAST", "url": "https://www.uniprot.org/uniprot/P43550", "type": "external" } ], "mass": 62135.0, "length": 591, "protein_name": "Dihydroxyacetone kinase 2", "gene_name": "DAK2", "organism": "Yeast", "refseq_name": "dihydroxyacetone kinase", "refseq_ac": [ { "id": "NP_116602", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116602", "type": "external" } ], "gene_names_uniprotkb": "DAK2", "gene_names_refseq": "DAK2", "protein_names_uniprotkb": "Dihydroxyacetone kinase 2; 2.7.1.28; 2.7.1.29; DHA kinase 2; Glycerone kinase 2; Triokinase 2; Triose kinase 2", "protein_names_refseq": "dihydroxyacetone kinase", "tax_id": 559292, "disease": "", "pathway": " (sce:YFL053W); (R-SCE-70350)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "18407956;21126336;24374639;7670463", "class_list": "", "function": "Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTH7", "ec_number_list": [ { "id": "2.7.1.28", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.28", "type": "external" }, { "id": "2.7.1.29", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.29", "type": "external" } ], "go_molecular_function": "GO:0004371 glycerone kinase activity;GO:0005524 ATP binding;GO:0050354 triokinase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0019563 glycerol catabolic process;GO:0019588 anaerobic glycerol catabolic process;GO:0061610 glycerol to glycerone phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P43550-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43551-1", "uniprot_id": [ { "id": "ZNF1_YEAST", "url": "https://www.uniprot.org/uniprot/P43551", "type": "external" } ], "mass": 53240.0, "length": 465, "protein_name": "Respiratory transcription factor ZNF1", "gene_name": "ZNF1", "organism": "Yeast", "refseq_name": "DNA-binding domain containing protein", "refseq_ac": [ { "id": "NP_116603", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116603", "type": "external" } ], "gene_names_uniprotkb": "ZNF1", "gene_names_refseq": "ZNF1", "protein_names_uniprotkb": "Respiratory transcription factor ZNF1; Zinc finger protein 1", "protein_names_refseq": "DNA-binding domain containing protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YFL052W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11353088;20975739;24374639;25673751;33481703;7670463", "class_list": "", "function": "Transcription factor that regulates respiratory growth and plays a critical role in stress adaptation during non-fermentative growth (PubMed:11353088, PubMed:20975739, PubMed:25673751). Binds to promoters of genes involved in non-fermentative metabolism, including processes such as gluconeogenesis (PCK1, FBP1 and MDH2), glyoxylate shunt (MLS1 and ICL1) and the tricarboxylic acid cycle (ACO1) (PubMed:25673751). Plays a role in maintaining mitochondrial morphology and function (PubMed:25673751). Also plays a role in tolerance to pH and osmotic stress, especially during the oxidative metabolism (PubMed:25673751)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTH8", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0071361 cellular response to ethanol", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P43551-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43553-1", "uniprot_id": [ { "id": "ALR2_YEAST", "url": "https://www.uniprot.org/uniprot/P43553", "type": "external" } ], "mass": 96684.0, "length": 858, "protein_name": "Magnesium transporter ALR2", "gene_name": "ALR2", "organism": "Yeast", "refseq_name": "putative Mg(2+) transporter ALR2", "refseq_ac": [ { "id": "NP_116604", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116604", "type": "external" } ], "gene_names_uniprotkb": "ALR2", "gene_names_refseq": "ALR2", "protein_names_uniprotkb": "Magnesium transporter ALR2; Aluminum resistance protein 2", "protein_names_refseq": "putative Mg(2+) transporter ALR2", "tax_id": 559292, "disease": "", "pathway": " (sce:YFL050C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;16847258;19779198;24374639;7670463;9430719", "class_list": "", "function": "Plasma membrane magnesium transporter., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTI0", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015095 magnesium ion transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0015693 magnesium ion transport;GO:0055085 transmembrane transport;GO:0006812 monoatomic cation transport;GO:0010961 intracellular magnesium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P43553-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43554-1", "uniprot_id": [ { "id": "SWP82_YEAST", "url": "https://www.uniprot.org/uniprot/P43554", "type": "external" } ], "mass": 70276.0, "length": 623, "protein_name": "SWI/SNF global transcription activator complex subunit SWP82", "gene_name": "SWP82", "organism": "Yeast", "refseq_name": "Swp82p", "refseq_ac": [ { "id": "NP_116605", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116605", "type": "external" } ], "gene_names_uniprotkb": "SWP82", "gene_names_refseq": "SWP82", "protein_names_uniprotkb": "SWI/SNF global transcription activator complex subunit SWP82", "protein_names_refseq": "Swp82p", "tax_id": 559292, "disease": "", "pathway": " (sce:YFL049W); (R-SCE-4551638)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "12524530;14562095;14562106;16204215;24374639;33491328;7670463", "class_list": "", "function": "Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTI1", "ec_number_list": [], "go_molecular_function": "GO:0031490 chromatin DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0016514 SWI/SNF complex;GO:0000785 chromatin;GO:0016586 RSC-type complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P43554-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43556-1", "uniprot_id": [ { "id": "RGD2_YEAST", "url": "https://www.uniprot.org/uniprot/P43556", "type": "external" } ], "mass": 82209.0, "length": 714, "protein_name": "Rho-GTPase-activating protein RGD2", "gene_name": "RGD2", "organism": "Yeast", "refseq_name": "GTPase-activating protein RGD2", "refseq_ac": [ { "id": "NP_428268", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_428268", "type": "external" } ], "gene_names_uniprotkb": "RGD2", "gene_names_refseq": "RGD2", "protein_names_uniprotkb": "Rho-GTPase-activating protein RGD2", "protein_names_refseq": "GTPase-activating protein RGD2", "tax_id": 559292, "disease": "chronic recurrent multifocal osteomyelitis (Disease Ontology:DOID:0060645); early-onset Parkinson's disease (Disease Ontology:DOID:0060894); autoinflammatory syndrome with cytopenia, hyperzincemia, and hypercalprotectinemia (Disease Ontology:DOID:0061185); PAPA syndrome (Disease Ontology:DOID:0080519); primary immunodeficiency disease (Disease Ontology:DOID:612)", "pathway": " (sce:YFL047W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11591390;14562106;17563356;24374639;33491328;7670463", "class_list": "", "function": "Acts in signal transduction. Activates CDC42 and RHO5., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTI3", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0032153 cell division site;GO:0000935 division septum;GO:0005934 cellular bud tip", "go_biological_process": "GO:0007010 cytoskeleton organization;GO:0007264 small GTPase-mediated signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P43556-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43557-1", "uniprot_id": [ { "id": "FMP32_YEAST", "url": "https://www.uniprot.org/uniprot/P43557", "type": "external" } ], "mass": 24019.0, "length": 207, "protein_name": "Protein FMP32, mitochondrial", "gene_name": "FMP32", "organism": "Yeast", "refseq_name": "Fmp32p", "refseq_ac": [ { "id": "NP_116608", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116608", "type": "external" } ], "gene_names_uniprotkb": "FMP32", "gene_names_refseq": "FMP32; PUT6", "protein_names_uniprotkb": "Protein FMP32, mitochondrial; Found in mitochondrial proteome protein 32", "protein_names_refseq": "Fmp32p", "tax_id": 559292, "disease": "", "pathway": " (sce:YFL046W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12514182;14562095;14576278;17322287;24374639;7670463", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTI4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0033617 mitochondrial respiratory chain complex IV assembly;GO:2000214 regulation of L-proline metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P43557-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43560-1", "uniprot_id": [ { "id": "LAM5_YEAST", "url": "https://www.uniprot.org/uniprot/P43560", "type": "external" } ], "mass": 76347.0, "length": 674, "protein_name": "Membrane-anchored lipid-binding protein LAM5", "gene_name": "LAM5", "organism": "Yeast", "refseq_name": "Lam5p", "refseq_ac": [ { "id": "NP_116611", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116611", "type": "external" } ], "gene_names_uniprotkb": "LAM5; LTC2", "gene_names_refseq": "LAM5; LTC2; YFL043C", "protein_names_uniprotkb": "Membrane-anchored lipid-binding protein LAM5; Lipid transfer at contact site protein 2; Lipid transfer protein anchored at membrane contact sites 1", "protein_names_refseq": "Lam5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YFL042C)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "17330950;18407956;19684113;19779198;20702584;21126336;23749301;24374639;25987606;26001273;32597660;33229814;33481703;33491328;7670463", "class_list": "", "function": "May be involved in sterol transfer between intracellular membranes., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 22, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 22, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 22, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 19, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 21, "binding_glycan_count": 0, "secondary_ac_list": "D6VTI7;P43559", "ec_number_list": [], "go_molecular_function": "GO:0032934 sterol binding;GO:0120015 sterol transfer activity", "go_cellular_component": "GO:0071561 nucleus-vacuole junction;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0032366 intracellular sterol transport", "synthesized_glycan_count": 0, "hit_score": 3.9, "record_id": "P43560-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43562-1", "uniprot_id": [ { "id": "YFE0_YEAST", "url": "https://www.uniprot.org/uniprot/P43562", "type": "external" } ], "mass": 60610.0, "length": 540, "protein_name": "Probable metabolite transport protein YFL040W", "gene_name": "", "organism": "Yeast", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_116613", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116613", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable metabolite transport protein YFL040W", "protein_names_refseq": "uncharacterized protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YFL040W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "16847258;24374639;33491328;7670463", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VTJ0", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0005366 myo-inositol:proton symporter activity", "go_cellular_component": "GO:0016020 membrane;GO:0000324 fungal-type vacuole;GO:0005628 prospore membrane", "go_biological_process": "GO:0055085 transmembrane transport;GO:1904679 myo-inositol import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P43562-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43569-1", "uniprot_id": [ { "id": "CAF16_YEAST", "url": "https://www.uniprot.org/uniprot/P43569", "type": "external" } ], "mass": 33090.0, "length": 289, "protein_name": "CCR4-associated factor 16", "gene_name": "CAF16", "organism": "Yeast", "refseq_name": "putative ATP-binding cassette family ATPase CAF16", "refseq_ac": [ { "id": "NP_116625", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116625", "type": "external" } ], "gene_names_uniprotkb": "CAF16", "gene_names_refseq": "CAF16", "protein_names_uniprotkb": "CCR4-associated factor 16", "protein_names_refseq": "putative ATP-binding cassette family ATPase CAF16", "tax_id": 559292, "disease": "", "pathway": " (sce:YFL028C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11113136;14562095;14562106;22814378;24374639;7670463", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, 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"P43569-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43574-1", "uniprot_id": [ { "id": "GAT1_YEAST", "url": "https://www.uniprot.org/uniprot/P43574", "type": "external" } ], "mass": 56328.0, "length": 510, "protein_name": "Transcriptional regulatory protein GAT1", "gene_name": "GAT1", "organism": "Yeast", "refseq_name": "Gat1p", "refseq_ac": [ { "id": "NP_116632", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116632", "type": "external" } ], "gene_names_uniprotkb": "GAT1", "gene_names_refseq": "GAT1; MEP80; NIL1", "protein_names_uniprotkb": "Transcriptional regulatory protein GAT1", "protein_names_refseq": "Gat1p", "tax_id": 559292, "disease": "familial atrial fibrillation (Disease Ontology:DOID:0050650); atrioventricular septal defect (Disease Ontology:DOID:0050651); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); myelodysplastic syndrome (Disease Ontology:DOID:0050908); congenital nonspherocytic hemolytic anemia 9 (Disease Ontology:DOID:0051008); colitis (Disease Ontology:DOID:0060180); atrial fibrillation (Disease Ontology:DOID:0060224); hypoparathyroidism-retardation-dysmorphism syndrome (Disease Ontology:DOID:0060348); hypoparathyroidism-deafness-renal disease syndrome (Disease Ontology:DOID:0060878); transient myeloproliferative syndrome (Disease Ontology:DOID:0060888); bicuspid aortic valve disease (Disease Ontology:DOID:0080332); myeloid leukemia associated with Down Syndrome (Disease Ontology:DOID:0080798); atrial heart septal defect 2 (Disease Ontology:DOID:0110107); atrial heart septal defect 9 (Disease Ontology:DOID:0110114); pancreatic hypoplasia-diabetes-congenital heart disease syndrome (Disease Ontology:DOID:0111733); X-linked thrombocytopenia with beta-thalassemia (Disease Ontology:DOID:0111767); immunodeficiency 21 (Disease Ontology:DOID:0111947); X-linked dyserythropoietic anemia (Disease Ontology:DOID:0112156); sensorineural hearing loss (Disease Ontology:DOID:10003); pre-eclampsia (Disease Ontology:DOID:10591); hypertension (Disease Ontology:DOID:10763); essential hypertension (Disease Ontology:DOID:10825); hypoparathyroidism (Disease Ontology:DOID:11199); beta thalassemia (Disease Ontology:DOID:12241); aplastic anemia (Disease Ontology:DOID:12449); dilated cardiomyopathy (Disease Ontology:DOID:12930); lung cancer (Disease Ontology:DOID:1324); major depressive disorder (Disease Ontology:DOID:1470); thrombocytopenia (Disease Ontology:DOID:1588); depressive disorder (Disease Ontology:DOID:1596); ventricular septal defect (Disease Ontology:DOID:1657); congenital heart disease (Disease Ontology:DOID:1682); atrial heart septal defect (Disease Ontology:DOID:1882); colon adenocarcinoma (Disease Ontology:DOID:234); nephrosis (Disease Ontology:DOID:2527); asthma (Disease Ontology:DOID:2841); congenital diaphragmatic hernia (Disease Ontology:DOID:3827); clear cell renal cell carcinoma (Disease Ontology:DOID:4467); Klatskin's tumor (Disease Ontology:DOID:4927); myelofibrosis (Disease Ontology:DOID:4971); myocardial infarction (Disease Ontology:DOID:5844); tetralogy of Fallot (Disease Ontology:DOID:6419); pulmonary hypertension (Disease Ontology:DOID:6432); autoimmune thyroiditis (Disease Ontology:DOID:7188); polycythemia (Disease Ontology:DOID:8432); myeloid leukemia (Disease Ontology:DOID:8692); acute myeloid leukemia (Disease Ontology:DOID:9119); Barrett's esophagus (Disease Ontology:DOID:9206); colorectal cancer (Disease Ontology:DOID:9256); acute myocardial infarction (Disease Ontology:DOID:9408)", "pathway": " (sce:YFL021W); (R-SCE-9018519)", "pathway_count": 2, "publication_count": 23, "publication_id_list": "14562106;15665377;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;24374639;26899143;27821475;30516470;32597660;33481703;33491328;7670463;8622686", "class_list": "", "function": "Positive regulator of multiple nitrogen catabolic genes., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 24, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 50, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VTK9", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P43574-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43577-1", "uniprot_id": [ { "id": "GNA1_YEAST", "url": "https://www.uniprot.org/uniprot/P43577", "type": "external" } ], "mass": 18135.0, "length": 159, "protein_name": "Glucosamine 6-phosphate N-acetyltransferase", "gene_name": "GNA1", "organism": "Yeast", "refseq_name": "glucosamine 6-phosphate N-acetyltransferase", "refseq_ac": [ { "id": "NP_116637", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116637", "type": "external" } ], "gene_names_uniprotkb": "GNA1; PAT1", "gene_names_refseq": "GNA1; PAT1", "protein_names_uniprotkb": "Glucosamine 6-phosphate N-acetyltransferase; 2.3.1.4; Phosphoglucosamine acetylase; Phosphoglucosamine transacetylase", "protein_names_refseq": "glucosamine 6-phosphate N-acetyltransferase", "tax_id": 559292, "disease": "keratosis follicularis spinulosa decalvans (Disease Ontology:DOID:0080753); cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YFL017C); (R-SCE-446210)", "pathway_count": 2, 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"reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTL3", "ec_number_list": [ { "id": "2.3.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.4", "type": "external" } ], "go_molecular_function": "GO:0004343 glucosamine 6-phosphate N-acetyltransferase activity;GO:0004059 aralkylamine N-acetyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006048 UDP-N-acetylglucosamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P43577-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43582-1", "uniprot_id": [ { "id": "WWM1_YEAST", "url": "https://www.uniprot.org/uniprot/P43582", "type": "external" } ], "mass": 22655.0, "length": 211, "protein_name": "WW domain-containing protein WWM1", "gene_name": "WWM1", "organism": "Yeast", "refseq_name": "Wwm1p", "refseq_ac": [ { "id": "NP_570898", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_570898", "type": "external" } ], "gene_names_uniprotkb": "WWM1", "gene_names_refseq": "WWM1", "protein_names_uniprotkb": "WW domain-containing protein WWM1; WW domain-containing protein interacting with metacaspase", "protein_names_refseq": "Wwm1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YFL010C)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10688190;11274415;12062425;14562095;14562106;14576278;16606443;19779198;21177495;22106047;23749301;24374639;33229814;33481703;33491328;7670463", "class_list": "", "function": "Involved in apoptosis. May play a role in nuclear function controlling cellular proliferation coupled to mitochondrial biogenesis. Causes impaired growth when overexpressed., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 6, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 6, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 6, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VTM0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P43582-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43589-1", "uniprot_id": [ { "id": "SAD1_YEAST", "url": "https://www.uniprot.org/uniprot/P43589", "type": "external" } ], "mass": 52167.0, "length": 448, "protein_name": "Pre-mRNA-splicing factor SAD1", "gene_name": "SAD1", "organism": "Yeast", "refseq_name": "mRNA splicing protein SAD1", "refseq_ac": [ { "id": "NP_116660", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116660", "type": "external" } ], "gene_names_uniprotkb": "SAD1", "gene_names_refseq": "SAD1", "protein_names_uniprotkb": "Pre-mRNA-splicing factor SAD1; snRNP assembly-defective protein 1", "protein_names_refseq": "mRNA splicing protein SAD1", "tax_id": 559292, "disease": "", "pathway": " (sce:YFR005C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10022888;11804584;14562095;14562106;17287358;17322287;19779198;22814378;24374639;32597660;33491328;7670463", "class_list": "", "function": "Promotes the assembly of newly synthesized U4 snRNA into the U4/U6 snRNP particle. Required for splicing of pre-mRNA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTN5", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005681 spliceosomal complex", "go_biological_process": "GO:0016579 protein deubiquitination;GO:0000398 mRNA splicing, via spliceosome;GO:0000245 spliceosomal complex assembly", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P43589-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43591-1", "uniprot_id": [ { "id": "YFH7_YEAST", "url": "https://www.uniprot.org/uniprot/P43591", "type": "external" } ], "mass": 39885.0, "length": 353, "protein_name": "ATP-dependent kinase YFH7", "gene_name": "YFH7", "organism": "Yeast", "refseq_name": "Yfh7p", "refseq_ac": [ { "id": "NP_116662", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116662", "type": "external" } ], "gene_names_uniprotkb": "YFH7; AIM12", "gene_names_refseq": "AIM12; YFH7", "protein_names_uniprotkb": "ATP-dependent kinase YFH7; 2.7.1.-; Altered inheritance of mitochondria protein 12", "protein_names_refseq": "Yfh7p", "tax_id": 559292, "disease": "", "pathway": " (sce:YFR007W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12868057;14562106;17322287;18004758;19300474;22814378;24374639;7670463", "class_list": "", "function": "ATP-dependent kinase that could be involved in endoplasmic reticulum membrane assembly., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTN7", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0016301 kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0016310 phosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P43591-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43592-1", "uniprot_id": [ { "id": "FAR7_YEAST", "url": "https://www.uniprot.org/uniprot/P43592", "type": "external" } ], "mass": 25915.0, "length": 221, "protein_name": "Factor arrest protein 7", "gene_name": "FAR7", "organism": "Yeast", "refseq_name": "Far7p", "refseq_ac": [ { "id": "NP_116663", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116663", "type": "external" } ], "gene_names_uniprotkb": "FAR7", "gene_names_refseq": "FAR7", "protein_names_uniprotkb": "Factor arrest protein 7", "protein_names_refseq": "Far7p", "tax_id": 559292, "disease": "", "pathway": " (sce:YFR008W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12588993;14562106;24374639;33491328;7670463", "class_list": "", "function": "Participates in the control of the reentry into the cell cycle following pheromone treatment., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTN8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0010506 regulation of autophagy;GO:0071444 cellular response to pheromone;GO:0000321 re-entry into mitotic cell cycle after pheromone arrest;GO:1903939 regulation of TORC2 signaling", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P43592-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43598-1", "uniprot_id": [ { "id": "IGD1_YEAST", "url": "https://www.uniprot.org/uniprot/P43598", "type": "external" } ], "mass": 21783.0, "length": 195, "protein_name": "Inhibitor of glycogen debranching 1", "gene_name": "IGD1", "organism": "Yeast", "refseq_name": "Igd1p", "refseq_ac": [ { "id": "NP_116672", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116672", "type": "external" } ], "gene_names_uniprotkb": "IGD1", "gene_names_refseq": "IGD1", "protein_names_uniprotkb": "Inhibitor of glycogen debranching 1", "protein_names_refseq": "Igd1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YFR017C)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "11875433;14562095;14562106;15665377;17287358;17322287;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;21585652;22218487;22814378;23749301;24374639;32597660;33481703;33491328;7670463", "class_list": "", "function": "Acts as an inhibitor of GDB1, enhancing the ability of cells to store glucose as glycogen., [UniProtKB, PubMed]", 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0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTP8", "ec_number_list": [], "go_molecular_function": "GO:0004857 enzyme inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045818 negative regulation of glycogen catabolic process;GO:0005978 glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P43598-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43606-1", "uniprot_id": [ { "id": "PTR3_YEAST", "url": "https://www.uniprot.org/uniprot/P43606", "type": "external" } ], "mass": 76286.0, "length": 678, "protein_name": "SPS-sensor component PTR3", "gene_name": "PTR3", "organism": "Yeast", "refseq_name": "Ptr3p", "refseq_ac": [ { "id": "NP_116685", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116685", "type": "external" } ], "gene_names_uniprotkb": "PTR3; APF3; SSY3", "gene_names_refseq": "PTR3; RAA2; SSY3", "protein_names_uniprotkb": "SPS-sensor component PTR3; Peptide transport protein 3", "protein_names_refseq": "Ptr3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YFR029W)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10409731;11154269;11489133;12502738;15947203;17984223;20702584;24374639;32597660;33481703;33491328;7670463;8686381;9483800;9701822", "class_list": "", "function": "Component of the SPS-sensor system, which regulates the expression of several amino acid-metabolizing enzymes and amino acid- and peptide-permeases in response to extracellular amino acid levels by controlling the activity of two transcription factors, STP1 and STP2., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTQ9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0043200 response to amino acid", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P43606-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43607-1", "uniprot_id": [ { "id": "RRT5_YEAST", "url": "https://www.uniprot.org/uniprot/P43607", "type": "external" } ], "mass": 31865.0, "length": 289, "protein_name": "Regulator of rDNA transcription protein 5", "gene_name": "RRT5", "organism": "Yeast", "refseq_name": "Rrt5p", "refseq_ac": [ { "id": "NP_116689", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116689", "type": "external" } ], "gene_names_uniprotkb": "RRT5", "gene_names_refseq": "RRT5", "protein_names_uniprotkb": "Regulator of rDNA transcription protein 5", "protein_names_refseq": "Rrt5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YFR032C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;19270272;24374639;7670463;8686381;9364751", "class_list": "", "function": "May be involved in the modulation of rDNA transcription., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTR3", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:1990904 ribonucleoprotein complex;GO:0005628 prospore membrane", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P43607-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43610-1", "uniprot_id": [ { "id": "IRC5_YEAST", "url": "https://www.uniprot.org/uniprot/P43610", "type": "external" } ], "mass": 96966.0, "length": 853, "protein_name": "Uncharacterized ATP-dependent helicase IRC5", "gene_name": "IRC5", "organism": "Yeast", "refseq_name": "putative ATPase", "refseq_ac": [ { "id": "NP_116696", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116696", "type": "external" } ], "gene_names_uniprotkb": "IRC5", "gene_names_refseq": "IRC5", "protein_names_uniprotkb": "Uncharacterized ATP-dependent helicase IRC5; 3.6.4.-; Increased recombination centers protein 5", "protein_names_refseq": "putative ATPase", "tax_id": 559292, "disease": "immunodeficiency-centromeric instability-facial anomalies syndrome 4 (Disease Ontology:DOID:0090011); high grade glioma (Disease Ontology:DOID:3070)", "pathway": " (sce:YFR038W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "12748633;12844361;18085829;22814378;23749301;24374639;32597660;33229814;33481703;33491328;7670463;8686381", "class_list": "", "function": "Is probably involved in a pathway contributing to genomic integrity., [UniProtKB]", 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"disease_count": 2, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VTS1", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0004386 helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0006312 mitotic recombination;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0031507 heterochromatin formation;GO:0070987 error-free translesion synthesis", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P43610-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43611-1", "uniprot_id": [ { "id": "OSW7_YEAST", "url": "https://www.uniprot.org/uniprot/P43611", "type": "external" } ], "mass": 59360.0, "length": 510, "protein_name": "Outer spore wall protein 7", "gene_name": "OSW7", "organism": "Yeast", "refseq_name": "Osw7p", "refseq_ac": [ { "id": "NP_116697", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116697", "type": "external" } ], "gene_names_uniprotkb": "OSW7", "gene_names_refseq": "OSW7", "protein_names_uniprotkb": "Outer spore wall protein 7", "protein_names_refseq": "Osw7p", "tax_id": 559292, "disease": "", "pathway": " (sce:YFR039C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;17330950;23966878;24374639;33491328;7670463;8686381", "class_list": "", "function": "Involved in spore wall assembly., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTS2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0030476 ascospore wall assembly", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P43611-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43613-1", "uniprot_id": [ { "id": "ERJ5_YEAST", "url": "https://www.uniprot.org/uniprot/P43613", "type": "external" } ], "mass": 34191.0, "length": 295, "protein_name": "ER-localized J domain-containing protein 5", "gene_name": "ERJ5", "organism": "Yeast", "refseq_name": "Erj5p", "refseq_ac": [ { "id": "NP_116699", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116699", "type": "external" } ], "gene_names_uniprotkb": "ERJ5", "gene_names_refseq": "ERJ5", "protein_names_uniprotkb": "ER-localized J domain-containing protein 5", "protein_names_refseq": "Erj5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YFR041C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;16847258;17157937;24374639;7670463;8686379", "class_list": "", "function": "DnaJ-like chaperone required for the folding capacity of the endoplasmic reticulum., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTS4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P43613-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43614-1", "uniprot_id": [ { "id": "KEG1_YEAST", "url": "https://www.uniprot.org/uniprot/P43614", "type": "external" } ], "mass": 23555.0, "length": 200, "protein_name": "Beta-1,6-glucan synthesis-associated protein KEG1", "gene_name": "KEG1", "organism": "Yeast", "refseq_name": "Keg1p", "refseq_ac": [ { "id": "NP_116700", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116700", "type": "external" } ], "gene_names_uniprotkb": "KEG1", "gene_names_refseq": "KEG1", "protein_names_uniprotkb": "Beta-1,6-glucan synthesis-associated protein KEG1; KRE6-binding ER protein responsible for glucan synthesis protein 1", "protein_names_refseq": "Keg1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YFR042W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "16847258;17893149;18439903;24374639;7670463;8686379", "class_list": "", "function": "Involved in the biosynthesis of (1->6)-beta-D-glucan polymers of the cell wall. Required for viability. Involved in maintaining chromosome stability., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A5A8M3;D6VTS5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0051276 chromosome organization;GO:0006078 (1->6)-beta-D-glucan biosynthetic process;GO:0071555 cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P43614-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43615-1", "uniprot_id": [ { "id": "IRC6_YEAST", "url": "https://www.uniprot.org/uniprot/P43615", "type": "external" } ], "mass": 27879.0, "length": 237, "protein_name": "Increased recombination centers protein 6", "gene_name": "IRC6", "organism": "Yeast", "refseq_name": "Irc6p", "refseq_ac": [ { "id": "NP_116701", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116701", "type": "external" } ], "gene_names_uniprotkb": "IRC6", "gene_names_refseq": "IRC6", "protein_names_uniprotkb": "Increased recombination centers protein 6", "protein_names_refseq": "Irc6p", "tax_id": 559292, "disease": "", "pathway": " (sce:YFR043C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "18085829;20194442;24374639;33491328;7670463;8686379", "class_list": "", "function": "Involved in gross chromosomal rearrangements (GCRs) and telomere healing., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTS6", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "", "go_biological_process": "GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P43615-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43619-1", "uniprot_id": [ { "id": "NADC_YEAST", "url": "https://www.uniprot.org/uniprot/P43619", "type": "external" } ], "mass": 32365.0, "length": 295, "protein_name": "Nicotinate-nucleotide pyrophosphorylase [carboxylating]", "gene_name": "BNA6", "organism": "Yeast", "refseq_name": "nicotinate-nucleotide diphosphorylase (carboxylating)", "refseq_ac": [ { "id": "NP_602317", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_602317", "type": "external" } ], "gene_names_uniprotkb": "BNA6; QPT1", "gene_names_refseq": "BNA6; QPT1", "protein_names_uniprotkb": "Nicotinate-nucleotide pyrophosphorylase [carboxylating]; 2.4.2.19; QAPRTase; Quinolinate phosphoribosyltransferase [decarboxylating]", "protein_names_refseq": "nicotinate-nucleotide diphosphorylase (carboxylating)", "tax_id": 559292, "disease": "Huntington's disease (Disease Ontology:DOID:12858); pellagra (Disease Ontology:DOID:8457)", "pathway": " (sce:YFR047C); (R-SCE-196807)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "12062417;14562095;14562106;18321072;21126336;24374639;33491328;7670463;8686379", "class_list": "glycogene;glycosyltransferase", "function": "Involved in the catabolism of quinolinic acid (QA)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTT0", "ec_number_list": [ { "id": "2.4.2.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.19", "type": "external" } ], "go_molecular_function": "GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0009435 NAD+ biosynthetic process;GO:0034213 quinolinate catabolic process;GO:0034354 'de novo' NAD+ biosynthetic process from L-tryptophan", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P43619-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43620-1", "uniprot_id": [ { "id": "RMD8_YEAST", "url": "https://www.uniprot.org/uniprot/P43620", "type": "external" } ], "mass": 75914.0, "length": 662, "protein_name": "Sporulation protein RMD8", "gene_name": "RMD8", "organism": "Yeast", "refseq_name": "Rmd8p", "refseq_ac": [ { "id": "NP_683716", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_683716", "type": "external" } ], "gene_names_uniprotkb": "RMD8", "gene_names_refseq": "RMD8", "protein_names_uniprotkb": "Sporulation protein RMD8; Required for meiotic nuclear division protein 8", "protein_names_refseq": "Rmd8p", "tax_id": 559292, "disease": "", "pathway": " (sce:YFR048W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "12586695;14562106;18407956;19779198;22814378;23749301;24374639;32597660;33229814;33481703;33491328;7670463;8686379", "class_list": "", "function": "Required for sporulation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VTT1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0051321 meiotic cell cycle;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P43620-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43621-1", "uniprot_id": [ { "id": "COPD_YEAST", "url": "https://www.uniprot.org/uniprot/P43621", "type": "external" } ], "mass": 60628.0, "length": 546, "protein_name": "Coatomer subunit delta", "gene_name": "RET2", "organism": "Yeast", "refseq_name": "coatomer subunit delta", "refseq_ac": [ { "id": "NP_116709", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116709", "type": "external" } ], "gene_names_uniprotkb": "RET2", "gene_names_refseq": "RET2", "protein_names_uniprotkb": "Coatomer subunit delta; Delta-COP; Delta-coat protein", "protein_names_refseq": "coatomer subunit delta", "tax_id": 559292, "disease": "", "pathway": " (sce:YFR051C); (R-SCE-6807878); (R-SCE-6811434)", "pathway_count": 3, "publication_count": 13, "publication_id_list": "14504276;14562106;17563356;18407956;19779198;21177495;23749301;24374639;32597660;33491328;7670463;8617224;8686379", "class_list": "", "function": "The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 18, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTT4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0030126 COPI vesicle coat", "go_biological_process": "GO:0015031 protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0051645 Golgi localization;GO:0048313 Golgi inheritance", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P43621-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43623-1", "uniprot_id": [ { "id": "METC_YEAST", "url": "https://www.uniprot.org/uniprot/P43623", "type": "external" } ], "mass": 36971.0, "length": 340, "protein_name": "Putative cystathionine beta-lyase", "gene_name": "IRC7", "organism": "Yeast", "refseq_name": "cysteine-S-conjugate beta-lyase IRC7", "refseq_ac": [ { "id": "NP_116714", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116714", "type": "external" } ], "gene_names_uniprotkb": "IRC7", "gene_names_refseq": "IRC7", "protein_names_uniprotkb": "Putative cystathionine beta-lyase; 4.4.1.13; Beta-cystathionase; CBL; Cysteine lyase; Cysteine-S-conjugate beta-lyase; Increased recombination centers protein 7", "protein_names_refseq": "cysteine-S-conjugate beta-lyase IRC7", "tax_id": 559292, "disease": "", "pathway": " (sce:YFR055W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;24374639;24440502;7670463;8686379", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTT7", "ec_number_list": [ { "id": "4.4.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.13", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0047804 cysteine-S-conjugate beta-lyase activity", "go_cellular_component": "", "go_biological_process": "GO:0006790 sulfur compound metabolic process;GO:0009086 methionine biosynthetic process;GO:0019346 transsulfuration;GO:0019450 L-cysteine catabolic process to pyruvate", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P43623-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43634-1", "uniprot_id": [ { "id": "CHA4_YEAST", "url": "https://www.uniprot.org/uniprot/P43634", "type": "external" } ], "mass": 74393.0, "length": 648, "protein_name": "Activatory protein CHA4", "gene_name": "CHA4", "organism": "Yeast", "refseq_name": "Cha4p", "refseq_ac": [ { "id": "NP_013199", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013199", "type": "external" } ], "gene_names_uniprotkb": "CHA4; L8004.8; SIL2; SIL3", "gene_names_refseq": "CHA4; SIL2; SIL3", "protein_names_uniprotkb": "Activatory protein CHA4", "protein_names_refseq": "Cha4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR098C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562106;17330950;18407956;19779198;21126336;23749301;24374639;32597660;33491328;8889513;9169871", "class_list": "", "function": "Activates the CHA1 gene for L-serine dehydratase. Binds to the DNA sequence 5'-GVGGARAYRTRATTCCRC-3'., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY98", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0009063 amino acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P43634-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P43637-1", "uniprot_id": [ { "id": "TOS3_YEAST", "url": "https://www.uniprot.org/uniprot/P43637", "type": "external" } ], "mass": 62091.0, "length": 560, "protein_name": "Serine/threonine-protein kinase TOS3", "gene_name": "TOS3", "organism": "Yeast", "refseq_name": "serine/threonine protein kinase TOS3", "refseq_ac": [ { "id": "NP_011336", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011336", "type": "external" } ], "gene_names_uniprotkb": "TOS3; G1618", "gene_names_refseq": "TOS3", "protein_names_uniprotkb": "Serine/threonine-protein kinase TOS3; 2.7.11.1; Target of SBF protein 3", "protein_names_refseq": "serine/threonine protein kinase TOS3", "tax_id": 559292, "disease": "high grade glioma (Disease Ontology:DOID:3070)", "pathway": " (sce:YGL179C)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "11062466;12748292;12847291;12906789;15340085;15824893;15879520;16054096;16201971;16607009;16835226;17438333;20489023;23749301;24374639;33491328;7668046;9169869", "class_list": "", "function": "One of the three SNF1 protein kinases (with SAK1 and ELM1) which are required for growth on nonfermentable carbon sources and nonpreferred sugars and for response to environmental stress. Activates SNF1 by phosphorylation of its activation-loop 'Thr-210'. Required for the regulation by SNF1 of the transcription of a large set of genes, the modification the activity of metabolic enzymes, and the control of various nutrient-responsive cellular developmental processes. Also phosphorylates GAL83, MIG1 and SIP2., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTX4", "ec_number_list": [ { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.1.26.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.26.-", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.67", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005777 peroxisome", "go_biological_process": "GO:0007165 signal transduction;GO:0042149 cellular response to glucose starvation;GO:1900180 regulation of protein localization to nucleus", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P43637-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P45819-1", "uniprot_id": [ { "id": "SPO74_YEAST", "url": "https://www.uniprot.org/uniprot/P45819", "type": "external" } ], "mass": 47700.0, "length": 413, "protein_name": "Sporulation-specific protein 74", "gene_name": "SPO74", "organism": "Yeast", "refseq_name": "Spo74p", "refseq_ac": [ { "id": "NP_011345", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011345", "type": "external" } ], "gene_names_uniprotkb": "SPO74; G1654", "gene_names_refseq": "SPO74", "protein_names_uniprotkb": "Sporulation-specific protein 74", "protein_names_refseq": "Spo74p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL170C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12796288;17322287;24374639;8896267;9169869", "class_list": "", "function": "Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation. Probable component of a core structural unit of the scaffold that initiates synthesis of the prospore membrane., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTY2;E9P8T5", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005816 spindle pole body;GO:0035974 meiotic spindle pole body", "go_biological_process": "GO:0030437 ascospore formation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P45819-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46151-1", "uniprot_id": [ { "id": "MTHR1_YEAST", "url": "https://www.uniprot.org/uniprot/P46151", "type": "external" } ], "mass": 73942.0, "length": 657, "protein_name": "Methylenetetrahydrofolate reductase 1", "gene_name": "MET12", "organism": "Yeast", "refseq_name": "methylenetetrahydrofolate reductase (NAD(P)H) MET12", "refseq_ac": [ { "id": "NP_015302", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015302", "type": "external" } ], "gene_names_uniprotkb": "MET12; LPB8C", "gene_names_refseq": "MET12", "protein_names_uniprotkb": "Methylenetetrahydrofolate reductase 1; 1.5.1.20", "protein_names_refseq": "methylenetetrahydrofolate reductase (NAD(P)H) MET12", "tax_id": 559292, "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589); diffuse large B-cell lymphoma (Disease Ontology:DOID:0050745); peripheral artery disease (Disease Ontology:DOID:0050830); non-arteritic anterior ischemic optic neuropathy (Disease Ontology:DOID:0050864); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); coarctation of the aorta (Disease Ontology:DOID:0051054); stroke (Disease Ontology:DOID:0051061); dextro-looped transposition of the great arteries (Disease Ontology:DOID:0060770); myeloid neoplasm (Disease Ontology:DOID:0070004); spina bifida (Disease Ontology:DOID:0080016); neural tube defect (Disease Ontology:DOID:0080074); hepatic veno-occlusive disease (Disease Ontology:DOID:0080177); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); graft-versus-host disease (Disease Ontology:DOID:0081267); thrombophilia due to thrombin defect (Disease Ontology:DOID:0111907); migraine with aura (Disease Ontology:DOID:10024); open-angle glaucoma (Disease Ontology:DOID:1067); kidney failure (Disease Ontology:DOID:1074); Kuhnt-Junius degeneration (Disease Ontology:DOID:10873); sickle cell anemia (Disease Ontology:DOID:10923); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); urinary bladder cancer (Disease Ontology:DOID:11054); Budd-Chiari syndrome (Disease Ontology:DOID:11512); nephrosclerosis (Disease Ontology:DOID:11664); portal vein thrombosis (Disease Ontology:DOID:11695); factor VIII deficiency (Disease Ontology:DOID:12134); male infertility (Disease Ontology:DOID:12336); Graves' disease (Disease Ontology:DOID:12361); cardiovascular system disease (Disease Ontology:DOID:1287); carotid stenosis (Disease Ontology:DOID:13001); angle-closure glaucoma (Disease Ontology:DOID:13550); alcoholic liver cirrhosis (Disease Ontology:DOID:14018); Down syndrome (Disease Ontology:DOID:14250); hypothyroidism (Disease Ontology:DOID:1459); thrombocytopenia (Disease Ontology:DOID:1588); retinal vein occlusion (Disease Ontology:DOID:1727); squamous cell carcinoma (Disease Ontology:DOID:1749); pancreatic cancer (Disease Ontology:DOID:1793); atherosclerosis (Disease Ontology:DOID:1936); rectal benign neoplasm (Disease Ontology:DOID:1984); hepatitis B (Disease Ontology:DOID:2043); nephroblastoma (Disease Ontology:DOID:2154); anemia (Disease Ontology:DOID:2355); renal artery disease (Disease Ontology:DOID:2388); thrombophilia (Disease Ontology:DOID:2452); transitional cell carcinoma (Disease Ontology:DOID:2671); asthma (Disease Ontology:DOID:2841); glomerulonephritis (Disease Ontology:DOID:2921); familial Mediterranean fever (Disease Ontology:DOID:2987); lipid metabolism disorder (Disease Ontology:DOID:3146); ischemia (Disease Ontology:DOID:326); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); osteosarcoma (Disease Ontology:DOID:3347); coronary artery disease (Disease Ontology:DOID:3393); cerebral infarction (Disease Ontology:DOID:3526); cervical cancer (Disease Ontology:DOID:4362); renal cell carcinoma (Disease Ontology:DOID:4450); clear cell renal cell carcinoma (Disease Ontology:DOID:4467); cholangiocarcinoma (Disease Ontology:DOID:4947); liver cirrhosis (Disease Ontology:DOID:5082); lung small cell carcinoma (Disease Ontology:DOID:5409); schizophrenia (Disease Ontology:DOID:5419); eye disease (Disease Ontology:DOID:5614); myocardial infarction (Disease Ontology:DOID:5844); mitral valve disease (Disease Ontology:DOID:61); migraine (Disease Ontology:DOID:6364); tetralogy of Fallot (Disease Ontology:DOID:6419); hepatocellular carcinoma (Disease Ontology:DOID:684); ankylosing spondylitis (Disease Ontology:DOID:7147); rheumatoid arthritis (Disease Ontology:DOID:7148); abdominal aortic aneurysm (Disease Ontology:DOID:7693); end stage renal disease (Disease Ontology:DOID:783); chronic kidney disease (Disease Ontology:DOID:784); hyperthyroidism (Disease Ontology:DOID:7998); cataract (Disease Ontology:DOID:83); chronic myeloid leukemia (Disease Ontology:DOID:8552); smallpox (Disease Ontology:DOID:8736); diabetic retinopathy (Disease Ontology:DOID:8947); acute myeloid leukemia (Disease Ontology:DOID:9119); liver benign neoplasm (Disease Ontology:DOID:916); hyperhomocysteinemia (Disease Ontology:DOID:9279); cleft lip (Disease Ontology:DOID:9296); type 2 diabetes mellitus (Disease Ontology:DOID:9352); hypopituitarism (Disease Ontology:DOID:9406); steatotic liver disease (Disease Ontology:DOID:9452); multiple myeloma (Disease Ontology:DOID:9538); aphthous stomatitis (Disease Ontology:DOID:9663); type 1 diabetes mellitus (Disease Ontology:DOID:9744); Meniere's disease (Disease Ontology:DOID:9849); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (sce:YPL023C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "17563356;18407956;19684113;19779198;20190278;24374639;32597660;33481703;33491328;6095044;7920641;9169875", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 90, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3Y9", "ec_number_list": [ { "id": "1.5.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.20", "type": "external" }, { "id": "1.5.1.53", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.53", "type": "external" } ], "go_molecular_function": "GO:0071949 FAD binding;GO:0004489 methylenetetrahydrofolate reductase [NAD(P)H] activity;GO:0106312 methylenetetrahydrofolate reductase (NADH) activity;GO:0106313 methylenetetrahydrofolate reductase (NADPH) activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0035999 tetrahydrofolate interconversion;GO:0009086 methionine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P46151-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46670-1", "uniprot_id": [ { "id": "TBCC_YEAST", "url": "https://www.uniprot.org/uniprot/P46670", "type": "external" } ], "mass": 30709.0, "length": 268, "protein_name": "Tubulin-specific chaperone C", "gene_name": "CIN2", "organism": "Yeast", "refseq_name": "GTPase-activating protein CIN2", "refseq_ac": [ { "id": "NP_015083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015083", "type": "external" } ], "gene_names_uniprotkb": "CIN2; P1043", "gene_names_refseq": "CIN2", "protein_names_uniprotkb": "Tubulin-specific chaperone C; Chromosome instability protein 2; Tubulin-folding cofactor C", "protein_names_refseq": "GTPase-activating protein CIN2", "tax_id": 559292, "disease": "retinitis pigmentosa (Disease Ontology:DOID:10584)", "pathway": " (sce:YPL241C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;22814378;24374639;33491328;9169875", "class_list": "", "function": "Tubulin-folding protein; involved in the early step of the tubulin folding pathway., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3D0;Q08973", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0005096 GTPase activator activity;GO:0036094 small molecule binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule", "go_biological_process": "GO:0006457 protein folding;GO:0007021 tubulin complex assembly;GO:0007023 post-chaperonin tubulin folding pathway", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P46670-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46784-1", "uniprot_id": [ { "id": "RS10B_YEAST", "url": "https://www.uniprot.org/uniprot/P46784", "type": "external" } ], "mass": 12738.0, "length": 105, "protein_name": "Small ribosomal subunit protein eS10B", "gene_name": "RPS10B", "organism": "Yeast", "refseq_name": "40S ribosomal protein eS10 RPS10B", "refseq_ac": [ { "id": "NP_013957", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013957", "type": "external" } ], "gene_names_uniprotkb": "RPS10B; YM9959.12", "gene_names_refseq": "RPS10B", "protein_names_uniprotkb": "Small ribosomal subunit protein eS10B; 40S ribosomal protein S10-B", "protein_names_refseq": "40S ribosomal protein eS10 RPS10B", "tax_id": 559292, "disease": "Diamond-Blackfan anemia 9 (Disease Ontology:DOID:0111884)", "pathway": " (sce:YMR230W); (R-SCE-156827); (R-SCE-1799339); (R-SCE-6791226); (R-SCE-72649); (R-SCE-72689); (R-SCE-72695); (R-SCE-72702); (R-SCE-72706); (R-SCE-975956); (R-SCE-975957); (R-SCE-9954714)", "pathway_count": 12, "publication_count": 20, "publication_id_list": "10601260;14562095;14562106;15665377;18407956;19684113;19795423;19823750;21177495;22096102;22218487;22814378;23749301;24374639;24524803;25437641;32597660;33491328;9169872;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102). eS10 plays a role as a positive regulator of the GCN2 kinase activity by stimulating GCN1-mediated GCN2 activation (PubMed:25437641)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W055", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0001934 positive regulation of protein phosphorylation;GO:0045860 positive regulation of protein kinase activity;GO:0000054 ribosomal subunit export from nucleus;GO:0034198 cellular response to amino acid starvation;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P46784-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46950-1", "uniprot_id": [ { "id": "SNG1_YEAST", "url": "https://www.uniprot.org/uniprot/P46950", "type": "external" } ], "mass": 61293.0, "length": 547, "protein_name": "Nitrosoguanidine resistance protein SNG1", "gene_name": "SNG1", "organism": "Yeast", "refseq_name": "Sng1p", "refseq_ac": [ { "id": "NP_011713", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011713", "type": "external" } ], "gene_names_uniprotkb": "SNG1; G7591", "gene_names_refseq": "SNG1", "protein_names_uniprotkb": "Nitrosoguanidine resistance protein SNG1", "protein_names_refseq": "Sng1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR197C)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "12529331;17330950;18407956;19779198;20702584;21126336;22218487;23749301;24374639;32597660;33481703;33491328;7502584;7753113;9169869", "class_list": "", "function": "May function as a N-methyl-N'nitro-N-nitrosoguanidine (MNNG) export permease., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUX9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0015931 nucleobase-containing compound transport;GO:0060237 regulation of fungal-type cell wall organization;GO:0061091 regulation of phospholipid translocation", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P46950-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46954-1", "uniprot_id": [ { "id": "SIP4_YEAST", "url": "https://www.uniprot.org/uniprot/P46954", "type": "external" } ], "mass": 96005.0, "length": 829, "protein_name": "Protein SIP4", "gene_name": "SIP4", "organism": "Yeast", "refseq_name": "Sip4p", "refseq_ac": [ { "id": "NP_012446", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012446", "type": "external" } ], "gene_names_uniprotkb": "SIP4; J0922", "gene_names_refseq": "SIP4", "protein_names_uniprotkb": "Protein SIP4", "protein_names_refseq": "Sip4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL089W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "24374639;33491328;7483841;8641269", "class_list": "", "function": "Interacts with the SNF1 protein kinase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW95", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045722 positive regulation of gluconeogenesis;GO:2000218 negative regulation of invasive growth in response to glucose limitation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P46954-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46955-1", "uniprot_id": [ { "id": "NCA3_YEAST", "url": "https://www.uniprot.org/uniprot/P46955", "type": "external" } ], "mass": 35412.0, "length": 337, "protein_name": "Beta-glucosidase-like protein NCA3, mitochondrial", "gene_name": "NCA3", "organism": "Yeast", "refseq_name": "SUN family protein NCA3", "refseq_ac": [ { "id": "NP_012419", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012419", "type": "external" } ], "gene_names_uniprotkb": "NCA3; J0748", "gene_names_refseq": "NCA3", "protein_names_uniprotkb": "Beta-glucosidase-like protein NCA3, mitochondrial", "protein_names_refseq": "SUN family protein NCA3", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL116C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "17322287;24374639;7586026;8641269;8948101", "class_list": "", "function": "Involved in the mitochondrial expression of subunits 6 and 8 of the F0-F1 ATP synthase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW68;E9P8T8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0009986 cell surface;GO:0000324 fungal-type vacuole;GO:0009277 fungal-type cell wall", "go_biological_process": "GO:0042776 proton motive force-driven mitochondrial ATP synthesis;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P46955-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46956-1", "uniprot_id": [ { "id": "PHO86_YEAST", "url": "https://www.uniprot.org/uniprot/P46956", "type": "external" } ], "mass": 34882.0, "length": 311, "protein_name": "Inorganic phosphate transporter PHO86", "gene_name": "PHO86", "organism": "Yeast", "refseq_name": "Pho86p", "refseq_ac": [ { "id": "NP_012418", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012418", "type": "external" } ], "gene_names_uniprotkb": "PHO86; J0744", "gene_names_refseq": "PHO86", "protein_names_uniprotkb": "Inorganic phosphate transporter PHO86", "protein_names_refseq": "Pho86p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL117W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "16847258;17322287;24374639;33481703;8598055;8641269;8948101", "class_list": "", "function": "Involved in the uptake of inorganic phosphate., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW67;E9P8T7", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0010966 regulation of phosphate transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006457 protein folding;GO:0006817 phosphate ion transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P46956-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46958-1", "uniprot_id": [ { "id": "IDS2_YEAST", "url": "https://www.uniprot.org/uniprot/P46958", "type": "external" } ], "mass": 53216.0, "length": 469, "protein_name": "IME2-dependent-signaling protein", "gene_name": "IDS2", "organism": "Yeast", "refseq_name": "Ids2p", "refseq_ac": [ { "id": "NP_012389", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012389", "type": "external" } ], "gene_names_uniprotkb": "IDS2; J0642", "gene_names_refseq": "IDS2", "protein_names_uniprotkb": "IME2-dependent-signaling protein", "protein_names_refseq": "Ids2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL146W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "14562106;15665377;17330950;18407956;19779198;20702584;21177495;22814378;23749301;24374639;30516470;32597660;33481703;33491328;7565676;8641269;8813765", "class_list": "", "function": "Seems to act indirectly to modify IME2 activity, thus permitting IME2 to carry out later meiotic functions., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 20, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW39", "ec_number_list": [], "go_molecular_function": "GO:0051087 protein-folding chaperone binding;GO:0016757 glycosyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006457 protein folding;GO:0051321 meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P46958-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46961-1", "uniprot_id": [ { "id": "GPI2_YEAST", "url": "https://www.uniprot.org/uniprot/P46961", "type": "external" } ], "mass": 32577.0, "length": 280, "protein_name": "Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit", "gene_name": "GPI2", "organism": "Yeast", "refseq_name": "phosphatidylinositol N-acetylglucosaminyltransferase", "refseq_ac": [ { "id": "NP_015249", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015249", "type": "external" } ], "gene_names_uniprotkb": "GPI2; GCR4; LPF9W", "gene_names_refseq": "GCR4; GPI2", "protein_names_uniprotkb": "Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit; 2.4.1.198; GPI-GlcNAc transferase complex subunit GPI2; GPI-GnT subunit GPI2", "protein_names_refseq": "phosphatidylinositol N-acetylglucosaminyltransferase", "tax_id": 559292, "disease": "glycosylphosphatidylinositol biosynthesis defect 16 (Disease Ontology:DOID:0081223)", "pathway": " (sce:YPL076W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "15163411;16847258;17322287;24374639;7502585;7768896;9169875", "class_list": "glycogene;glycosyltransferase", "function": "Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3U0;P48014", "ec_number_list": [ { "id": "2.4.1.198", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.198", "type": "external" } ], "go_molecular_function": "GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006506 GPI anchor biosynthetic process;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P46961-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46969-1", "uniprot_id": [ { "id": "RPE_YEAST", "url": "https://www.uniprot.org/uniprot/P46969", "type": "external" } ], "mass": 25967.0, "length": 238, "protein_name": "Ribulose-phosphate 3-epimerase", "gene_name": "RPE1", "organism": "Yeast", "refseq_name": "ribulose-phosphate 3-epimerase RPE1", "refseq_ac": [ { "id": "NP_012414", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012414", "type": "external" } ], "gene_names_uniprotkb": "RPE1; EPI1; J0731; POS18", "gene_names_refseq": "EPI1; POS18; RPE1", "protein_names_uniprotkb": "Ribulose-phosphate 3-epimerase; 5.1.3.1; PPE; Pentose-5-phosphate 3-epimerase; RPE", "protein_names_refseq": "ribulose-phosphate 3-epimerase RPE1", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL121C); (R-SCE-71336)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "14562106;17322287;18407956;24374639;32597660;33481703;33491328;8641269;8879247;8929392;8948101", "class_list": "", "function": "Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate (By similarity). Involved in the protective response to oxidative stress., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW65", "ec_number_list": [ { "id": "5.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.3.1", "type": "external" } ], "go_molecular_function": "GO:0004750 D-ribulose-phosphate 3-epimerase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0009052 pentose-phosphate shunt, non-oxidative branch;GO:0005975 carbohydrate metabolic process;GO:0006098 pentose-phosphate shunt", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P46969-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46970-1", "uniprot_id": [ { "id": "NMD5_YEAST", "url": "https://www.uniprot.org/uniprot/P46970", "type": "external" } ], "mass": 119967.0, "length": 1048, "protein_name": "Nonsense-mediated mRNA decay protein 5", "gene_name": "NMD5", "organism": "Yeast", "refseq_name": "Nmd5p", "refseq_ac": [ { "id": "NP_012666", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012666", "type": "external" } ], "gene_names_uniprotkb": "NMD5; J2112; KAP119", "gene_names_refseq": "KAP119; NMD5", "protein_names_uniprotkb": "Nonsense-mediated mRNA decay protein 5; Karyopherin-119", "protein_names_refseq": "Nmd5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR132W)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "14562095;14562106;17563356;18407956;19779198;19795423;19823750;20702584;23749301;24374639;30516470;33481703;33491328;8641269;9852143", "class_list": "", "function": "Active in protein import into the nucleus. Its major import substrate is transcription elongation factor TFIIS., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWV0", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding;GO:0061608 nuclear import signal receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0034399 nuclear periphery", "go_biological_process": "GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P46970-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46973-1", "uniprot_id": [ { "id": "HIT1_YEAST", "url": "https://www.uniprot.org/uniprot/P46973", "type": "external" } ], "mass": 18376.0, "length": 164, "protein_name": "Protein HIT1", "gene_name": "HIT1", "organism": "Yeast", "refseq_name": "Hit1p", "refseq_ac": [ { "id": "NP_012589", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012589", "type": "external" } ], "gene_names_uniprotkb": "HIT1; J1705", "gene_names_refseq": "HIT1", "protein_names_uniprotkb": "Protein HIT1", "protein_names_refseq": "Hit1p", "tax_id": 559292, "disease": "PEHO syndrome (Disease Ontology:DOID:0080539)", "pathway": " (sce:YJR055W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "1325386;14562106;17322287;24374639;8641269;8840504", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWM6", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0070761 pre-snoRNP complex", "go_biological_process": "GO:0000492 box C/D snoRNP assembly;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P46973-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46974-1", "uniprot_id": [ { "id": "RSF2_YEAST", "url": "https://www.uniprot.org/uniprot/P46974", "type": "external" } ], "mass": 155063.0, "length": 1380, "protein_name": "Respiration factor 2", "gene_name": "RSF2", "organism": "Yeast", "refseq_name": "Rsf2p", "refseq_ac": [ { "id": "NP_012661", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012661", "type": "external" } ], "gene_names_uniprotkb": "RSF2; J2052; ZMS1", "gene_names_refseq": "RSF2; ZMS1", "protein_names_uniprotkb": "Respiration factor 2; Zinc finger protein ZMS1", "protein_names_refseq": "Rsf2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR127C)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "14562095;16208474;17287358;17563356;18407956;19111667;19779198;19795423;19823750;21126336;23749301;24374639;30516470;32597660;33481703;33491328;8641269;9171100", "class_list": "", "function": "Transcription factor that regulates expression of both nuclear and mitochondrial genes, and more specifically those required for glycerol-based growth and respiration., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 24, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VWU6", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P46974-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46982-1", "uniprot_id": [ { "id": "MNN5_YEAST", "url": "https://www.uniprot.org/uniprot/P46982", "type": "external" } ], "mass": 67204.0, "length": 586, "protein_name": "Alpha-1,2-mannosyltransferase MNN5", "gene_name": "MNN5", "organism": "Yeast", "refseq_name": "alpha-1,2-mannosyltransferase MNN5", "refseq_ac": [ { "id": "NP_012349", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012349", "type": "external" } ], "gene_names_uniprotkb": "MNN5; J0409", "gene_names_refseq": "MNN5", "protein_names_uniprotkb": "Alpha-1,2-mannosyltransferase MNN5; 2.4.1.-", "protein_names_refseq": "alpha-1,2-mannosyltransferase MNN5", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL186W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;20236934;24374639;6802821;6995454;8641269;9756928", "class_list": "glycogene;glycosyltransferase", "function": "Responsible for addition of first and second mannose residues to the outer chain of core N-linked polysaccharides and to O-linked mannotriose. Implicated in late Golgi modifications., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 4, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VW04", "ec_number_list": [], "go_molecular_function": "GO:0000026 alpha-1,2-mannosyltransferase activity", "go_cellular_component": "GO:0005794 Golgi apparatus", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0046354 mannan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P46982-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000011000.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46983-1", "uniprot_id": [ { "id": "ATG36_YEAST", "url": "https://www.uniprot.org/uniprot/P46983", "type": "external" } ], "mass": 33740.0, "length": 293, "protein_name": "Autophagy-related protein 36", "gene_name": "ATG36", "organism": "Yeast", "refseq_name": "Atg36p", "refseq_ac": [ { "id": "NP_012350", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012350", "type": "external" } ], "gene_names_uniprotkb": "ATG36; J0415", "gene_names_refseq": "ATG36", "protein_names_uniprotkb": "Autophagy-related protein 36", "protein_names_refseq": "Atg36p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL185C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "17146497;17322287;18407956;19779198;22643220;23749301;24374639;25287303;33491328;8641269", "class_list": "", "function": "Required for autophagic breakdown of peroxisomes, called pexophagy, through linking peroxisomes to the autophagy apparatus. Involved in regulation of the glyoxylate cycle., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW05", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0000423 mitophagy;GO:0000425 pexophagy", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P46983-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46988-1", "uniprot_id": [ { "id": "PFD1_YEAST", "url": "https://www.uniprot.org/uniprot/P46988", "type": "external" } ], "mass": 12782.0, "length": 109, "protein_name": "Prefoldin subunit 1", "gene_name": "PFD1", "organism": "Yeast", "refseq_name": "prefolding complex chaperone subunit", "refseq_ac": [ { "id": "NP_012356", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012356", "type": "external" } ], "gene_names_uniprotkb": "PFD1; GIM6; J0488", "gene_names_refseq": "GIM6; PFD1", "protein_names_uniprotkb": "Prefoldin subunit 1; Genes involved in microtubule biogenesis protein 6; Gim complex subunit 6; GimC subunit 6", "protein_names_refseq": "prefolding complex chaperone subunit", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL179W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;17322287;21126336;22814378;24374639;33491328;8641269;9878052", "class_list": "", "function": "Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW10;E9P8V7", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016272 prefoldin complex", "go_biological_process": "GO:0007010 cytoskeleton organization;GO:0006457 protein folding;GO:0032968 positive regulation of transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P46988-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46992-1", "uniprot_id": [ { "id": "TOH1_YEAST", "url": "https://www.uniprot.org/uniprot/P46992", "type": "external" } ], "mass": 42958.0, "length": 396, "protein_name": "Probable circularly permuted 1,3-beta-glucanase YJL171C", "gene_name": "TOH1", "organism": "Yeast", "refseq_name": "Toh1p", "refseq_ac": [ { "id": "NP_012364", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012364", "type": "external" } ], "gene_names_uniprotkb": "TOH1; J0512", "gene_names_refseq": "TOH1", "protein_names_uniprotkb": "Probable circularly permuted 1,3-beta-glucanase YJL171C; 3.2.1.39; TOS1 homolog", "protein_names_refseq": "Toh1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL171C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10383953;12644457;14562106;14739279;18434410;22842922;24374639;33481703;8641269;9613572", "class_list": "", "function": "Probable circularly permuted 1,3-beta-glucanase involved in cell wall modification through beta-1,3-glucan network alterations such as increased branching or remodeling., [UniProtKB, UniProtKB]", "predicted_glycosites": 11, "predicted_n_glycosites": 11, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 11, "binding_glycan_count": 0, "secondary_ac_list": "D6VW17", "ec_number_list": [], "go_molecular_function": "GO:0042973 glucan endo-1,3-beta-D-glucosidase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0071555 cell wall organization", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P46992-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46993-1", "uniprot_id": [ { "id": "ASG7_YEAST", "url": "https://www.uniprot.org/uniprot/P46993", "type": "external" } ], "mass": 24946.0, "length": 209, "protein_name": "Protein ASG7", "gene_name": "ASG7", "organism": "Yeast", "refseq_name": "Asg7p", "refseq_ac": [ { "id": "NP_012365", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012365", "type": "external" } ], "gene_names_uniprotkb": "ASG7; J0514", "gene_names_refseq": "ASG7", "protein_names_uniprotkb": "Protein ASG7; A-specific gene 7 protein", "protein_names_refseq": "Asg7p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL170C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10568744;11073982;11073983;12748633;13680367;16847258;17330950;23749301;24374639;33481703;33491328;8641269", "class_list": "", "function": "Required for receptor inhibition of inappropriately expressed a-factor receptor (STE3) in MAT a cells. Inhibits signaling by relocalizing the G protein beta-gamma (STE4-STE18) subunit to intracellular membranes. May also be a mechanism for the down-regulation of the mating pheromone response after the zygotic fusion event, promoting the transition of the new diploid cell to vegetative growth., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW18", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0000747 conjugation with cellular fusion", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P46993-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46997-1", "uniprot_id": [ { "id": "JJJ2_YEAST", "url": "https://www.uniprot.org/uniprot/P46997", "type": "external" } ], "mass": 67389.0, "length": 583, "protein_name": "J protein JJJ2", "gene_name": "JJJ2", "organism": "Yeast", "refseq_name": "Jjj2p", "refseq_ac": [ { "id": "NP_012373", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012373", "type": "external" } ], "gene_names_uniprotkb": "JJJ2; J0549", "gene_names_refseq": "JJJ2", "protein_names_uniprotkb": "J protein JJJ2", "protein_names_refseq": "Jjj2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL162C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "12748633;14562095;14562106;15170475;17563356;18407956;19779198;23749301;24374639;32597660;33481703;33491328;8641269", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW25", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0042026 protein refolding", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P46997-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P46999-1", "uniprot_id": [ { "id": "PIR5_YEAST", "url": "https://www.uniprot.org/uniprot/P46999", "type": "external" } ], "mass": 30215.0, "length": 287, "protein_name": "Cell wall protein PIR5", "gene_name": "PIR5", "organism": "Yeast", "refseq_name": "beta-1,3-glucan linked protein", "refseq_ac": [ { "id": "NP_012375", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012375", "type": "external" } ], "gene_names_uniprotkb": "PIR5; J0555", "gene_names_refseq": "PIR5", "protein_names_uniprotkb": "Cell wall protein PIR5; Protein with internal repeats 5", "protein_names_refseq": "beta-1,3-glucan linked protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL160C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12586695;12748633;12844361;16278933;24374639;8641269", "class_list": "", "function": "Component of the outer cell wall layer (By similarity). May be involved in meiosis and sporulation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW27;Q86ZS0", "ec_number_list": [], "go_molecular_function": "GO:0005199 structural constituent of cell wall", "go_cellular_component": "GO:0000324 fungal-type vacuole;GO:0009277 fungal-type cell wall", "go_biological_process": "GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P46999-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47007-1", "uniprot_id": [ { "id": "MRX5_YEAST", "url": "https://www.uniprot.org/uniprot/P47007", "type": "external" } ], "mass": 44863.0, "length": 382, "protein_name": "MIOREX complex component 5", "gene_name": "MRX5", "organism": "Yeast", "refseq_name": "Smt1p", "refseq_ac": [ { "id": "NP_012388", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012388", "type": "external" } ], "gene_names_uniprotkb": "MRX5; J0639", "gene_names_refseq": "MRX5; SMT1", "protein_names_uniprotkb": "MIOREX complex component 5; Mitochondrial organization of gene expression protein 5", "protein_names_refseq": "Smt1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL147C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;14562106;24374639;25683707;8641269;8813765", "class_list": "", "function": "Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW38", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P47007-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47015-1", "uniprot_id": [ { "id": "IF3M_YEAST", "url": "https://www.uniprot.org/uniprot/P47015", "type": "external" } ], "mass": 41461.0, "length": 356, "protein_name": "Translation initiation factor IF-3, mitochondrial", "gene_name": "AIM23", "organism": "Yeast", "refseq_name": "Aim23p", "refseq_ac": [ { "id": "NP_012404", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012404", "type": "external" } ], "gene_names_uniprotkb": "AIM23; 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J0718", "gene_names_refseq": "MTC1", "protein_names_uniprotkb": "Maintenance of telomere capping protein 1", "protein_names_refseq": "DUF5427 domain-containing protein MTC1", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL123C)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "14562095;14562106;16702403;17330950;17563356;18407956;18845848;19779198;19795423;19823750;20702584;21126336;21177495;23749301;24374639;24909858;30516470;32597660;33481703;33491328;34965436;8641269;8948101", "class_list": "", "function": "Involved in telomere capping., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 29, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW63", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005794 Golgi apparatus;GO:0030137 COPI-coated vesicle", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P47018-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47031-1", "uniprot_id": [ { "id": "IML2_YEAST", "url": "https://www.uniprot.org/uniprot/P47031", "type": "external" } ], "mass": 82536.0, "length": 731, "protein_name": "Inclusion body clearance protein IML2", "gene_name": "IML2", "organism": "Yeast", "refseq_name": "Iml2p", "refseq_ac": [ { "id": "NP_012453", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012453", "type": "external" } ], "gene_names_uniprotkb": "IML2; J1007", "gene_names_refseq": "IML2", "protein_names_uniprotkb": "Inclusion body clearance protein IML2; Increased minichromosome loss protein 2", "protein_names_refseq": "Iml2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL082W)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "10628851;14562095;14562106;15665377;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21177495;23749301;24374639;26004510;27821475;30516470;32597660;33481703;33491328;7483841;8641269", "class_list": "", "function": "Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins. Involved in LD-mediated IB clearing after protein folding stress, probably by enabling access to the IBs of an LD-stored soluble sterol derivative that acts as a chaperone in inclusion clearing., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 25, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWA1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0071218 cellular response to misfolded protein", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P47031-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47040-1", "uniprot_id": [ { "id": "BTN1_YEAST", "url": "https://www.uniprot.org/uniprot/P47040", "type": "external" } ], "mass": 46383.0, "length": 408, "protein_name": "Protein BTN1", "gene_name": "YHC3", "organism": "Yeast", "refseq_name": "amino acid transporter YHC3", "refseq_ac": [ { "id": "NP_012476", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012476", "type": "external" } ], "gene_names_uniprotkb": "YHC3; BTN1; J1139", "gene_names_refseq": "BTN1; YHC3", "protein_names_uniprotkb": "Protein BTN1", "protein_names_refseq": "amino acid transporter YHC3", "tax_id": 559292, "disease": "neuronal ceroid lipofuscinosis 1 (Disease Ontology:DOID:0110721); neuronal ceroid lipofuscinosis 3 (Disease Ontology:DOID:0110731); neuronal ceroid lipofuscinosis (Disease Ontology:DOID:14503)", "pathway": " (sce:YJL059W); (R-SCE-9845576)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "10319861;11053386;14660799;15701790;17322287;24374639;8641269;9219333;9753630", "class_list": "", "function": "Plays a role in vacuolar arginine transport. Involved in pH homeostasis. May be involved in ion homeostasis together with IST2. Not necessary for mitochondrial function or ATP synthase degradation., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWC3;O60004;Q6B1E1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005774 vacuolar membrane;GO:0005773 vacuole;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0051453 regulation of intracellular pH;GO:0015819 lysine transport;GO:1903826 L-arginine transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P47040-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47042-1", "uniprot_id": [ { "id": "IKS1_YEAST", "url": "https://www.uniprot.org/uniprot/P47042", "type": "external" } ], "mass": 75327.0, "length": 667, "protein_name": "Probable serine/threonine-protein kinase IKS1", "gene_name": "IKS1", "organism": "Yeast", "refseq_name": "protein kinase IKS1", "refseq_ac": [ { "id": "NP_012478", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012478", "type": "external" } ], "gene_names_uniprotkb": "IKS1; J1143", "gene_names_refseq": "IKS1", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase IKS1; 2.7.11.1; IRA1 kinase suppressor 1", "protein_names_refseq": "protein kinase IKS1", "tax_id": 559292, "disease": "dystonia 33 (Disease Ontology:DOID:0060940); Alzheimer's disease (Disease Ontology:DOID:10652); Huntington's disease (Disease Ontology:DOID:12858); Parkinson's disease (Disease Ontology:DOID:14330); hepatitis B (Disease Ontology:DOID:2043); amyotrophic lateral sclerosis (Disease Ontology:DOID:332)", "pathway": " (sce:YJL057C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10407277;14562106;17563356;18407956;19779198;21126336;23749301;24374639;32597660;33481703;33491328;8641269", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWC5", "ec_number_list": [ { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.1.26.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.26.-", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.67", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006468 protein phosphorylation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P47042-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47046-1", "uniprot_id": [ { "id": "IRC8_YEAST", "url": "https://www.uniprot.org/uniprot/P47046", "type": "external" } ], "mass": 91256.0, "length": 822, "protein_name": "Uncharacterized protein IRC8", "gene_name": "IRC8", "organism": "Yeast", "refseq_name": "Irc8p", "refseq_ac": [ { "id": "NP_012484", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012484", "type": "external" } ], "gene_names_uniprotkb": "IRC8; J1156", "gene_names_refseq": "IRC8", "protein_names_uniprotkb": "Uncharacterized protein IRC8; Increased recombination centers protein 8", "protein_names_refseq": "Irc8p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL051W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "16847258;19779198;21126336;21177495;23749301;24374639;32597660;33481703;33491328;8641269", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 35, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWD2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole;GO:0005933 cellular bud", "go_biological_process": "GO:0006312 mitotic recombination", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P47046-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47051-1", "uniprot_id": [ { "id": "LPLA_YEAST", "url": "https://www.uniprot.org/uniprot/P47051", "type": "external" } ], "mass": 47003.0, "length": 409, "protein_name": "Putative lipoate-protein ligase A", "gene_name": "AIM22", "organism": "Yeast", "refseq_name": "putative lipoate--protein ligase", "refseq_ac": [ { "id": "NP_012489", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012489", "type": "external" } ], "gene_names_uniprotkb": "AIM22; J1171", "gene_names_refseq": "AIM22; LIP3; RRG3", "protein_names_uniprotkb": "Putative lipoate-protein ligase A; 6.3.1.20; Altered inheritance rate of mitochondria protein 22", "protein_names_refseq": "putative lipoate--protein ligase", "tax_id": 559292, "disease": "Leigh disease (Disease Ontology:DOID:3652)", "pathway": " (sce:YJL046W); (R-SCE-9857492)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "15905473;17322287;24374639;8641269", "class_list": "", "function": "Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWD8", "ec_number_list": [ { "id": "2.3.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.12", "type": "external" }, { "id": "2.3.1.61", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.61", "type": "external" }, { "id": "6.3.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.1.20", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016979 lipoate-protein ligase activity;GO:0017118 lipoyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0009249 protein lipoylation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P47051-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47052-1", "uniprot_id": [ { "id": "SDHX_YEAST", "url": "https://www.uniprot.org/uniprot/P47052", "type": "external" } ], "mass": 69382.0, "length": 634, "protein_name": "Succinate dehydrogenase [ubiquinone] flavoprotein subunit 2, mitochondrial", "gene_name": "J1194", "organism": "Yeast", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "J1194", "gene_names_refseq": "", "protein_names_uniprotkb": "Succinate dehydrogenase [ubiquinone] flavoprotein subunit 2, mitochondrial; 1.3.5.1; FP; Flavoprotein subunit of complex II; SDH1b", "protein_names_refseq": "", "tax_id": 559292, "disease": "mitochondrial complex II deficiency (Disease Ontology:DOID:0060537); pheochromocytoma/paraganglioma syndrome 5 (Disease Ontology:DOID:0061220); dilated cardiomyopathy 1GG (Disease Ontology:DOID:0110435); Parkinson's disease (Disease Ontology:DOID:14330); Leigh disease (Disease Ontology:DOID:3652); lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": " (sce:YJL045W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "19779198;24374639;8641269;9730279", "class_list": "", "function": "Probable minor catalytic subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Probably forms a catalytic dimer with SDH2. Electrons flow from succinate to the FAD bound to the catalytic subunit, and sequentially through the iron-sulfur clusters bound to SDH2 and enter the membrane dimer formed by SDH3 and SDH4., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWD9", "ec_number_list": [ { "id": "1.3.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.5.1", "type": "external" } ], "go_molecular_function": "GO:0009055 electron transfer activity;GO:0050660 flavin adenine dinucleotide binding;GO:0008177 succinate dehydrogenase (quinone) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045273 respiratory chain complex II (succinate dehydrogenase)", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006121 mitochondrial electron transport, succinate to ubiquinone;GO:0045333 cellular respiration", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P47052-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47055-1", "uniprot_id": [ { "id": "LOH1_YEAST", "url": "https://www.uniprot.org/uniprot/P47055", "type": "external" } ], "mass": 24843.0, "length": 219, "protein_name": "Outer spore wall protein 4", "gene_name": "LOH1", "organism": "Yeast", "refseq_name": "Loh1p", "refseq_ac": [ { "id": "NP_012496", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012496", "type": "external" } ], "gene_names_uniprotkb": "LOH1; J1232; OSW4", "gene_names_refseq": "LOH1; OSW4", "protein_names_uniprotkb": "Outer spore wall protein 4; Loss of heterozygosity protein 1", "protein_names_refseq": "Loh1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL038C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12612074;16847258;17322287;18562670;19756047;19779569;23966878;24374639;8641269;9784122", "class_list": "", "function": "Involved in spore wall assembly (PubMed:23966878). May be involved in maintaining genome integrity (PubMed:18562670)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VWE5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0051276 chromosome organization;GO:0030476 ascospore wall assembly", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P47055-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47056-1", "uniprot_id": [ { "id": "IRC18_YEAST", "url": "https://www.uniprot.org/uniprot/P47056", "type": "external" } ], "mass": 24746.0, "length": 224, "protein_name": "Outer spore wall protein 6", "gene_name": "IRC18", "organism": "Yeast", "refseq_name": "Irc18p", "refseq_ac": [ { "id": "NP_012497", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012497", "type": "external" } ], "gene_names_uniprotkb": "IRC18; J1234; OSW6", "gene_names_refseq": "IRC18; OSW6", "protein_names_uniprotkb": "Outer spore wall protein 6; Increased recombination centers protein 18", "protein_names_refseq": "Irc18p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL037W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "11179416;14561723;17322287;18085829;21177495;23966878;24374639;29897761;8641269", "class_list": "", "function": "Involved in spore wall assembly., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VWE6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0030476 ascospore wall assembly", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P47056-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47064-1", "uniprot_id": [ { "id": "AP3S_YEAST", "url": "https://www.uniprot.org/uniprot/P47064", "type": "external" } ], "mass": 21938.0, "length": 194, "protein_name": "AP-3 complex subunit sigma", "gene_name": "APS3", "organism": "Yeast", "refseq_name": "Aps3p", "refseq_ac": [ { "id": "NP_012510", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012510", "type": "external" } ], "gene_names_uniprotkb": "APS3; J1274; YKS7", "gene_names_refseq": "APS3; YKS7", "protein_names_uniprotkb": "AP-3 complex subunit sigma; AP-3 complex sigma3A subunit; Adaptor-related protein complex 3 subunit sigma; Clathrin-associated/assembly/adaptor protein, small 3; Sigma-adaptin 3A; Sigma3-adaptin", "protein_names_refseq": "Aps3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL024C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10559961;14562095;14562106;24374639;33491328;8641269;9250663;9335339", "class_list": "", "function": "Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole. Required for the transport via the ALP pathway, which directs the transport of the cargo proteins PHO8 and VAM3 to the vacuole., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWF8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0030659 cytoplasmic vesicle membrane;GO:0030123 AP-3 adaptor complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0016192 vesicle-mediated transport;GO:0006623 protein targeting to vacuole;GO:0006896 Golgi to vacuole transport", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P47064-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47079-1", "uniprot_id": [ { "id": "TCPQ_YEAST", "url": "https://www.uniprot.org/uniprot/P47079", "type": "external" } ], "mass": 61662.0, "length": 568, "protein_name": "T-complex protein 1 subunit theta", "gene_name": "CCT8", "organism": "Yeast", "refseq_name": "chaperonin-containing T-complex subunit CCT8", "refseq_ac": [ { "id": "NP_012526", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012526", "type": "external" } ], "gene_names_uniprotkb": "CCT8; J1374", "gene_names_refseq": "CCT8", "protein_names_uniprotkb": "T-complex protein 1 subunit theta; CCT-theta; TCP-1-theta", "protein_names_refseq": "chaperonin-containing T-complex subunit CCT8", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL008C); (R-SCE-390471); (R-SCE-6798695); (R-SCE-6814122)", "pathway_count": 4, "publication_count": 7, "publication_id_list": "12872131;19779198;21126336;24374639;33481703;33491328;8641269", "class_list": "", "function": "Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. In yeast may play a role in mitotic spindle formation (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWG8", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity;GO:0140662 ATP-dependent protein folding chaperone", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005832 chaperonin-containing T-complex", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P47079-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47081-1", "uniprot_id": [ { "id": "COX16_YEAST", "url": "https://www.uniprot.org/uniprot/P47081", "type": "external" } ], "mass": 14077.0, "length": 118, "protein_name": "Cytochrome c oxidase assembly protein COX16, mitochondrial", "gene_name": "COX16", "organism": "Yeast", "refseq_name": "Cox16p", "refseq_ac": [ { "id": "NP_012531", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012531", "type": "external" } ], "gene_names_uniprotkb": "COX16; J1403; YJR83.2", "gene_names_refseq": "COX16", "protein_names_uniprotkb": "Cytochrome c oxidase assembly protein COX16, mitochondrial", "protein_names_refseq": "Cox16p", "tax_id": 559292, "disease": "mitochondrial complex IV deficiency nuclear type 22 (Disease Ontology:DOID:0070507)", "pathway": " (sce:YJL003W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12446688;14562106;14576278;17322287;24374639;28821616;8641269", "class_list": "", "function": "Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase (PubMed:12446688, PubMed:28821616). May participate in merging the COX1 and COX2 assembly lines (PubMed:28821616)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWH2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0033617 mitochondrial respiratory chain complex IV assembly", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P47081-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47084-1", "uniprot_id": [ { "id": "MRX12_YEAST", "url": "https://www.uniprot.org/uniprot/P47084", "type": "external" } ], "mass": 59766.0, "length": 519, "protein_name": "MIOREX complex component 12", "gene_name": "MRX12", "organism": "Yeast", "refseq_name": "Mrx12p", "refseq_ac": [ { "id": "NP_012536", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012536", "type": "external" } ], "gene_names_uniprotkb": "MRX12; J1415; YJR83.30", "gene_names_refseq": "MRX12", "protein_names_uniprotkb": "MIOREX complex component 12; Mitochondrial organization of gene expression protein 12", "protein_names_refseq": "Mrx12p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR003C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12748633;12775844;14562095;14562106;16823961;24374639;25683707;33491328;8641269", "class_list": "", "function": "Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VWH7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P47084-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47085-1", "uniprot_id": [ { "id": "MHO1_YEAST", "url": "https://www.uniprot.org/uniprot/P47085", "type": "external" } ], "mass": 38482.0, "length": 338, "protein_name": "MEMO1 family protein MHO1", "gene_name": "MHO1", "organism": "Yeast", "refseq_name": "Mho1p", "refseq_ac": [ { "id": "NP_012541", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012541", "type": "external" } ], "gene_names_uniprotkb": "MHO1; J1431; YJR83.9", "gene_names_refseq": "MHO1", "protein_names_uniprotkb": "MEMO1 family protein MHO1; Memo-homolog 1", "protein_names_refseq": "Mho1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR008W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11102521;12871953;14561723;14562106;22412880;24374639;33491328;8641269", "class_list": "", "function": "Plays a role in haploid invasive growth under conditions of nutrient insufficiency, suggesting that the function of the MEMO1 family in cell motility/invasion is conserved across species., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VWI3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P47085-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47088-1", "uniprot_id": [ { "id": "GPI14_YEAST", "url": "https://www.uniprot.org/uniprot/P47088", "type": "external" } ], "mass": 47166.0, "length": 403, "protein_name": "GPI mannosyltransferase 1", "gene_name": "GPI14", "organism": "Yeast", "refseq_name": "glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I", "refseq_ac": [ { "id": "NP_012547", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012547", "type": "external" } ], "gene_names_uniprotkb": "GPI14; J1444; PMH1; YJR83.11", "gene_names_refseq": "GPI14; PMH1", "protein_names_uniprotkb": "GPI mannosyltransferase 1; 2.4.1.-; GPI mannosyltransferase I; GPI-MT-I; Glycosylphosphatidylinositol-anchor biosynthesis protein 14", "protein_names_refseq": "glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR013W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12844361;14562095;16134120;16847258;17322287;24374639;8641269", "class_list": "glycogene;glycosyltransferase", "function": "Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWI9;E9P8R4", "ec_number_list": [], "go_molecular_function": "GO:0000030 mannosyltransferase activity;GO:0004376 GPI mannosyltransferase activity;GO:0051751 alpha-1,4-mannosyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:1990529 glycosylphosphatidylinositol-mannosyltransferase I complex", "go_biological_process": "GO:0006506 GPI anchor biosynthetic process;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P47088-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47089-1", "uniprot_id": [ { "id": "DENR_YEAST", "url": "https://www.uniprot.org/uniprot/P47089", "type": "external" } ], "mass": 22495.0, "length": 198, "protein_name": "Translation machinery-associated protein 22", "gene_name": "TMA22", "organism": "Yeast", "refseq_name": "Tma22p", "refseq_ac": [ { "id": "NP_012548", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012548", "type": "external" } ], "gene_names_uniprotkb": "TMA22; J1446; RBF22; YJR83.12", "gene_names_refseq": "TMA22", "protein_names_uniprotkb": "Translation machinery-associated protein 22; Density-regulated protein homolog", "protein_names_refseq": "Tma22p", "tax_id": 559292, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041)", "pathway": " (sce:YJR014W)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10093218;14562095;14562106;16702403;17322287;18407956;21126336;23749301;24374639;24909858;30516470;33481703;33491328;34965436;8641269", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWJ0", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0002188 translation reinitiation;GO:0032790 ribosome disassembly;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0001731 formation of translation preinitiation complex", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P47089-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47095-1", "uniprot_id": [ { "id": "MTNB_YEAST", "url": "https://www.uniprot.org/uniprot/P47095", "type": "external" } ], "mass": 27427.0, "length": 244, "protein_name": "Methylthioribulose-1-phosphate dehydratase", "gene_name": "MDE1", "organism": "Yeast", "refseq_name": "methylthioribulose 1-phosphate dehydratase MDE1", "refseq_ac": [ { "id": "NP_012558", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012558", "type": "external" } ], "gene_names_uniprotkb": "MDE1; J1545; YJR83.18", "gene_names_refseq": "MDE1", "protein_names_uniprotkb": "Methylthioribulose-1-phosphate dehydratase; 4.2.1.109; MTRu-1-P dehydratase", "protein_names_refseq": "methylthioribulose 1-phosphate dehydratase MDE1", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR024C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;17322287;18625006;19795423;19823750;24374639;8619316;8641269", "class_list": "", "function": "Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P)., [UniProtKB, HAMAP, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWJ7", "ec_number_list": [ { "id": "4.2.1.109", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.109", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0046570 methylthioribulose 1-phosphate dehydratase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0019509 L-methionine salvage from methylthioadenosine", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P47095-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47099-1", "uniprot_id": [ { "id": "YJ12A_YEAST", "url": "https://www.uniprot.org/uniprot/P47099", "type": "external" } ], "mass": 49112.0, "length": 440, "protein_name": "Transposon Ty1-JR2 Gag polyprotein", "gene_name": "TY1A-JR2", "organism": "Yeast", "refseq_name": "gag protein", "refseq_ac": [ { "id": "NP_012563", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012563", "type": "external" } ], "gene_names_uniprotkb": "TY1A-JR2; J1565; YJRWTy1-2 GAG", "gene_names_refseq": "", "protein_names_uniprotkb": "Transposon Ty1-JR2 Gag polyprotein; Gag-p45; Gag-p49; TY1A; TYA; Transposon Ty1 protein A; p54; p58", "protein_names_refseq": "gag protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR028W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11884596;16093660;24374639;33229814;8619316;8641269;9582191", "class_list": "", "function": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 6, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 6, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 6, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "D6VWK2", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P47099-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47111-1", "uniprot_id": [ { "id": "VPS55_YEAST", "url": "https://www.uniprot.org/uniprot/P47111", "type": "external" } ], "mass": 15664.0, "length": 140, "protein_name": "Vacuolar protein sorting-associated protein 55", "gene_name": "VPS55", "organism": "Yeast", "refseq_name": "Vps55p", "refseq_ac": [ { "id": "NP_012578", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012578", "type": "external" } ], "gene_names_uniprotkb": "VPS55; J1637", "gene_names_refseq": "VPS55", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 55", "protein_names_refseq": "Vps55p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR044C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "12006663;14562095;14562106;16847258;17322287;19779198;21126336;24374639;33481703;33491328;7668047;8641269", "class_list": "", "function": "Involved in protein transport from endosomes to the vacuole., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWL5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005768 endosome;GO:0005770 late endosome;GO:0034424 Vps55/Vps68 complex", "go_biological_process": "GO:0015031 protein transport;GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P47111-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47125-1", "uniprot_id": [ { "id": "I23O_YEAST", "url": "https://www.uniprot.org/uniprot/P47125", "type": "external" } ], "mass": 50775.0, "length": 453, "protein_name": "Indoleamine 2,3-dioxygenase", "gene_name": "BNA2", "organism": "Yeast", "refseq_name": "dioxygenase BNA2", "refseq_ac": [ { "id": "NP_012612", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012612", "type": "external" } ], "gene_names_uniprotkb": "BNA2; J1840", "gene_names_refseq": "BNA2", "protein_names_uniprotkb": "Indoleamine 2,3-dioxygenase; 1.13.11.52; Biosynthesis of nicotinic acid protein 2; IDO", "protein_names_refseq": "dioxygenase BNA2", "tax_id": 559292, "disease": "pre-eclampsia (Disease Ontology:DOID:10591); chlamydia (Disease Ontology:DOID:11263); dengue disease (Disease Ontology:DOID:12205); toxic shock syndrome (Disease Ontology:DOID:14115); pulmonary tuberculosis (Disease Ontology:DOID:2957); acquired immunodeficiency syndrome (Disease Ontology:DOID:635); eczema herpeticum (Disease Ontology:DOID:9123)", "pathway": " (sce:YJR078W); (R-SCE-71240)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "12062417;12756250;12972620;14562106;18828915;21170645;23481038;24374639;33491328;8641269;8840504", "class_list": "", "function": "Catalyzes the first step in tryptophan catabolism in order to supply de novo nicotinamide adenine dinucleotide (NAD(+)) via the kynurenine pathway. Plays a role in the cellular response to telomere uncapping., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWP8", "ec_number_list": [ { "id": "1.13.11.52", "url": "https://www.rhea-db.org/rhea/?query=ec:1.13.11.52", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0004833 L-tryptophan 2,3-dioxygenase activity;GO:0033754 indoleamine 2,3-dioxygenase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0019441 L-tryptophan catabolic process to kynurenine;GO:0034354 'de novo' NAD+ biosynthetic process from L-tryptophan", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P47125-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47127-1", "uniprot_id": [ { "id": "AIM24_YEAST", "url": "https://www.uniprot.org/uniprot/P47127", "type": "external" } ], "mass": 44428.0, "length": 394, "protein_name": "Altered inheritance of mitochondria protein 24, mitochondrial", "gene_name": "AIM24", "organism": "Yeast", "refseq_name": "Aim24p", "refseq_ac": [ { "id": "NP_012614", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012614", "type": "external" } ], "gene_names_uniprotkb": "AIM24; FMP26; J1847", "gene_names_refseq": "AIM24; FMP26", "protein_names_uniprotkb": "Altered inheritance of mitochondria protein 24, mitochondrial; Found in mitochondrial proteome protein 26", "protein_names_refseq": "Aim24p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR080C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;19300474;22218487;24374639;8641269;8840504", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWQ0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0007007 inner mitochondrial membrane organization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P47127-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47135-1", "uniprot_id": [ { "id": "JSN1_YEAST", "url": "https://www.uniprot.org/uniprot/P47135", "type": "external" } ], "mass": 120374.0, "length": 1091, "protein_name": "Protein JSN1", "gene_name": "JSN1", "organism": "Yeast", "refseq_name": "Jsn1p", "refseq_ac": [ { "id": "NP_012624", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012624", "type": "external" } ], "gene_names_uniprotkb": "JSN1; 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DPH4; J1931", "gene_names_refseq": "DPH4; JJJ3", "protein_names_uniprotkb": "Diphthamide biosynthesis protein 4; J protein type 3", "protein_names_refseq": "Jjj3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR097W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;15170475;15485916;17322287;18627462;22814378;24374639;8641269", "class_list": "", "function": "Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWR6", "ec_number_list": [], "go_molecular_function": "GO:0008198 ferrous iron binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0017183 protein histidyl modification to diphthamide", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P47138-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47140-1", "uniprot_id": [ { "id": "AIM25_YEAST", "url": "https://www.uniprot.org/uniprot/P47140", "type": "external" } ], "mass": 37480.0, "length": 327, "protein_name": "Altered inheritance rate of mitochondria protein 25", "gene_name": "AIM25", "organism": "Yeast", "refseq_name": "Aim25p", "refseq_ac": [ { "id": "NP_012634", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012634", "type": "external" } ], "gene_names_uniprotkb": "AIM25; J1946", "gene_names_refseq": "AIM25; SLM35", "protein_names_uniprotkb": "Altered inheritance rate of mitochondria protein 25", "protein_names_refseq": "Aim25p", "tax_id": 559292, "disease": "obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YJR100C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14690591;16823961;20702584;24374639;8641269", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWR9", "ec_number_list": [], "go_molecular_function": "GO:0017128 phospholipid scramblase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005886 plasma membrane", "go_biological_process": "GO:0034605 cellular response to heat;GO:0034599 cellular response to oxidative stress;GO:0017121 plasma membrane phospholipid scrambling;GO:1903147 negative regulation of autophagy of mitochondrion", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P47140-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47141-1", "uniprot_id": [ { "id": "RT26_YEAST", "url": "https://www.uniprot.org/uniprot/P47141", "type": "external" } ], "mass": 30224.0, "length": 266, "protein_name": "Small ribosomal subunit protein mS42", "gene_name": "RSM26", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein mS42 RSM26", "refseq_ac": [ { "id": "NP_012635", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012635", "type": "external" } ], "gene_names_uniprotkb": "RSM26; 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The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWS0", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004784 superoxide dismutase activity;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P47141-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47147-1", "uniprot_id": [ { "id": "YMR1_YEAST", "url": "https://www.uniprot.org/uniprot/P47147", "type": "external" } ], "mass": 80152.0, "length": 688, "protein_name": "Phosphoinositide 3-phosphatase", "gene_name": "YMR1", "organism": "Yeast", "refseq_name": "phosphatidylinositol-3-phosphatase YMR1", "refseq_ac": [ { "id": "NP_012644", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012644", "type": "external" } ], "gene_names_uniprotkb": "YMR1; J2007", "gene_names_refseq": "YMR1", "protein_names_uniprotkb": "Phosphoinositide 3-phosphatase; 3.1.3.64; Yeast myotubularin-related protein 1", "protein_names_refseq": "phosphatidylinositol-3-phosphatase YMR1", "tax_id": 559292, "disease": "Charcot-Marie-Tooth disease type 4B1 (Disease Ontology:DOID:0110191); centronuclear myopathy X-linked (Disease Ontology:DOID:0111225); Charcot-Marie-Tooth disease (Disease Ontology:DOID:10595); centronuclear myopathy (Disease Ontology:DOID:14717); congenital structural myopathy (Disease Ontology:DOID:422); myopathy (Disease Ontology:DOID:423); muscular atrophy (Disease Ontology:DOID:767)", "pathway": " (sce:YJR110W); (R-SCE-1483248); (R-SCE-1632852); (R-SCE-1660499); (R-SCE-1660516); (R-SCE-1660517)", "pathway_count": 6, "publication_count": 12, "publication_id_list": "10900271;14562095;14562106;15169871;18407956;19779198;20489023;24374639;2689869;33481703;33491328;8641269", "class_list": "", "function": "Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P). 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J2009", "gene_names_refseq": "PXP2", "protein_names_uniprotkb": "Peroxisomal protein 2", "protein_names_refseq": "Pxp2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR111C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;22814378;24374639;27392156;33491328;8641269", "class_list": "", "function": "Probably involved in peroxisome formation or maintenance as well as in amino acid metabolism., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWT0", "ec_number_list": [], "go_molecular_function": "GO:0051920 peroxiredoxin activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005777 peroxisome;GO:0005782 peroxisomal matrix;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P47148-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47150-1", "uniprot_id": [ { "id": "RT07_YEAST", "url": "https://www.uniprot.org/uniprot/P47150", "type": "external" } ], "mass": 27816.0, "length": 247, "protein_name": "Small ribosomal subunit protein uS7m", "gene_name": "RSM7", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein uS7m RSM7", "refseq_ac": [ { "id": "NP_012647", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012647", "type": "external" } ], "gene_names_uniprotkb": "RSM7; J2020", "gene_names_refseq": "RSM7; uS7m", "protein_names_uniprotkb": "Small ribosomal subunit protein uS7m; 37S ribosomal protein S7, mitochondrial", "protein_names_refseq": "mitochondrial 37S ribosomal protein uS7m RSM7", "tax_id": 559292, "disease": "combined oxidative phosphorylation deficiency 34 (Disease Ontology:DOID:0111497)", "pathway": " (sce:YJR113C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "11278769;12392552;14562095;14562106;14576278;17322287;24374639;25609543;28154081;33491328;8641269", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWT3", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0019843 rRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005840 ribosome", "go_biological_process": "GO:0006412 translation;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P47150-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47153-1", "uniprot_id": [ { "id": "TDA4_YEAST", "url": "https://www.uniprot.org/uniprot/P47153", "type": "external" } ], "mass": 32011.0, "length": 279, "protein_name": "Topoisomerase I damage affected protein 4", "gene_name": "TDA4", "organism": "Yeast", "refseq_name": "Tda4p", "refseq_ac": [ { "id": "NP_012650", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012650", "type": "external" } ], "gene_names_uniprotkb": "TDA4; J2031", "gene_names_refseq": "TDA4", "protein_names_uniprotkb": "Topoisomerase I damage affected protein 4", "protein_names_refseq": "Tda4p", "tax_id": 559292, "disease": "chromosome 16p11.2 deletion syndrome, 593-kb (Disease Ontology:DOID:0070515)", "pathway": " (sce:YJR116W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "16847258;21173034;24374639;8641269", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWT5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0055088 lipid homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P47153-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47155-1", "uniprot_id": [ { "id": "ILM1_YEAST", "url": "https://www.uniprot.org/uniprot/P47155", "type": "external" } ], "mass": 23645.0, "length": 203, "protein_name": "Protein ILM1", "gene_name": "ILM1", "organism": "Yeast", "refseq_name": "Ilm1p", "refseq_ac": [ { "id": "NP_012652", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012652", "type": "external" } ], "gene_names_uniprotkb": "ILM1; J2033", "gene_names_refseq": "ILM1", "protein_names_uniprotkb": "Protein ILM1; Increased loss of mitochondrial DNA protein 1", "protein_names_refseq": "Ilm1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR118C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562095;14562106;16847258;24374639;8641269", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWT7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P47155-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47161-1", "uniprot_id": [ { "id": "VPS70_YEAST", "url": "https://www.uniprot.org/uniprot/P47161", "type": "external" } ], "mass": 92018.0, "length": 811, "protein_name": "Vacuolar protein sorting-associated protein 70", "gene_name": "VPS70", "organism": "Yeast", "refseq_name": "putative zinc metalloprotease", "refseq_ac": [ { "id": "NP_012660", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012660", "type": "external" } ], "gene_names_uniprotkb": "VPS70; J2050", "gene_names_refseq": "VPS70", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 70; 3.4.-.-", "protein_names_refseq": "putative zinc metalloprotease", "tax_id": 559292, "disease": "hemochromatosis type 3 (Disease Ontology:DOID:0111030); immunodeficiency 46 (Disease Ontology:DOID:0111948); prostate cancer (Disease Ontology:DOID:10283); iron deficiency anemia (Disease Ontology:DOID:11758); breast cancer (Disease Ontology:DOID:1612); hemochromatosis (Disease Ontology:DOID:2352); ovarian cancer (Disease Ontology:DOID:2394); transitional cell carcinoma (Disease Ontology:DOID:2671); breast carcinoma (Disease Ontology:DOID:3459); cerebral infarction (Disease Ontology:DOID:3526); cervical adenocarcinoma (Disease Ontology:DOID:3702); renal cell carcinoma (Disease Ontology:DOID:4450); abdominal aortic aneurysm (Disease Ontology:DOID:7693); acute myeloid leukemia (Disease Ontology:DOID:9119); multiple myeloma (Disease Ontology:DOID:9538)", "pathway": " (sce:YJR126C); (R-SCE-8963693); (R-SCE-8980692); (R-SCE-9013106); (R-SCE-9013406); (R-SCE-9696273)", "pathway_count": 6, "publication_count": 5, "publication_id_list": "12134085;14562106;24374639;33481703;8641269", "class_list": "", "function": "Involved in vacuolar protein sorting., [UniProtKB, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VWU5", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "3.4.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.-.-", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "1.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.3", "type": "external" }, { "id": "1.2.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.64", "type": "external" }, { "id": "3.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.-.-.-", "type": "external" } ], "go_molecular_function": "GO:0008237 metallopeptidase activity;GO:0046872 metal ion binding;GO:0004180 carboxypeptidase activity;GO:0004177 aminopeptidase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0006623 protein targeting to vacuole", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P47161-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47165-1", "uniprot_id": [ { "id": "XPT1_YEAST", "url": "https://www.uniprot.org/uniprot/P47165", "type": "external" } ], "mass": 23671.0, "length": 209, "protein_name": "Xanthine phosphoribosyltransferase 1", "gene_name": "XPT1", "organism": "Yeast", "refseq_name": "xanthine phosphoribosyltransferase", "refseq_ac": [ { "id": "NP_012667", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012667", "type": "external" } ], "gene_names_uniprotkb": "XPT1; J2118", "gene_names_refseq": "XPT1", "protein_names_uniprotkb": "Xanthine phosphoribosyltransferase 1; 2.4.2.-; XPRT", "protein_names_refseq": "xanthine phosphoribosyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR133W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10217799;14562095;14562106;18407956;24374639;8641269", "class_list": "", "function": "May act as a xanthine phosphoribosyltransferase involved in the synthesis of purine nucleotides. Such activity is however unclear in vivo., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWV1", "ec_number_list": [], "go_molecular_function": "GO:0004422 hypoxanthine phosphoribosyltransferase activity;GO:0000310 xanthine phosphoribosyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0032264 IMP salvage;GO:0046100 hypoxanthine metabolic process;GO:0032263 GMP salvage;GO:0032265 XMP salvage", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P47165-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47166-1", "uniprot_id": [ { "id": "SGM1_YEAST", "url": "https://www.uniprot.org/uniprot/P47166", "type": "external" } ], "mass": 81171.0, "length": 707, "protein_name": "Protein SGM1", "gene_name": "SGM1", "organism": "Yeast", "refseq_name": "Sgm1p", "refseq_ac": [ { "id": "NP_012668", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012668", "type": "external" } ], "gene_names_uniprotkb": "SGM1; J2120", "gene_names_refseq": "SGM1", "protein_names_uniprotkb": "Protein SGM1; Slow growth on galactose and mannose protein 1", "protein_names_refseq": "Sgm1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR134C); (R-SCE-6811440)", "pathway_count": 2, "publication_count": 18, "publication_id_list": "10628851;14562095;14562106;16473623;17330950;18407956;19779198;19795423;19823750;21126336;21177495;22814378;23749301;24374639;32597660;33481703;33491328;8641269", "class_list": "", "function": "Required for normal growth rate on galactose and mannose., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 32, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWV2", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P47166-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47172-1", "uniprot_id": [ { "id": "YJ9I_YEAST", "url": "https://www.uniprot.org/uniprot/P47172", "type": "external" } ], "mass": 39902.0, "length": 347, "protein_name": "Uncharacterized protein YJR141W", "gene_name": "J2166", "organism": "Yeast", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "J2166", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein YJR141W", "protein_names_refseq": "", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR141W); (R-SCE-983168)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "17322287;24374639;8641269", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWW0", "ec_number_list": [], "go_molecular_function": "GO:0061630 ubiquitin protein ligase activity;GO:0031624 ubiquitin conjugating enzyme binding;GO:0030332 cyclin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0000209 protein polyubiquitination;GO:0031397 negative regulation of protein ubiquitination;GO:0051865 protein autoubiquitination;GO:0031442 positive regulation of mRNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P47172-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47175-1", "uniprot_id": [ { "id": "HMS2_YEAST", "url": "https://www.uniprot.org/uniprot/P47175", "type": "external" } ], "mass": 41192.0, "length": 358, "protein_name": "Probable transcription factor HMS2", "gene_name": "HMS2", "organism": "Yeast", "refseq_name": "Hms2p", "refseq_ac": [ { "id": "NP_012681", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012681", "type": "external" } ], "gene_names_uniprotkb": "HMS2; 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1.13.12.16; Nitroalkane oxidase", "protein_names_refseq": "putative nitronate monooxygenase", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR149W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562095;14562106;24374639;33491328;8641269", "class_list": "", "function": "Catalyzes the oxidation of alkyl nitronates to produce the corresponding carbonyl compounds and nitrites., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWW7", "ec_number_list": [ { "id": "1.13.12.16", "url": "https://www.rhea-db.org/rhea/?query=ec:1.13.12.16", "type": "external" } ], "go_molecular_function": "GO:0018580 nitronate monooxygenase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P47177-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47179-1", "uniprot_id": [ { "id": "DAN4_YEAST", "url": "https://www.uniprot.org/uniprot/P47179", "type": "external" } ], "mass": 118360.0, "length": 1161, "protein_name": "Cell wall protein DAN4", "gene_name": "DAN4", "organism": "Yeast", "refseq_name": "Dan4p", "refseq_ac": [ { "id": "NP_012685", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012685", "type": "external" } ], "gene_names_uniprotkb": "DAN4; J2223", "gene_names_refseq": "DAN4", "protein_names_uniprotkb": "Cell wall protein DAN4; Delayed anaerobic protein 4", "protein_names_refseq": "Dan4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR151C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11160904;11292809;16086015;24374639;8641269;9613572", "class_list": "", "function": "Component of the cell wall., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VWW9", "ec_number_list": [], "go_molecular_function": "GO:0005199 structural constituent of cell wall", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P47179-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47180-1", "uniprot_id": [ { "id": "PGLR_YEAST", "url": "https://www.uniprot.org/uniprot/P47180", "type": "external" } ], "mass": 37287.0, "length": 361, "protein_name": "Polygalacturonase", "gene_name": "PGU1", "organism": "Yeast", "refseq_name": "endo-polygalacturonase", "refseq_ac": [ { "id": "NP_012687", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012687", "type": "external" } ], "gene_names_uniprotkb": "PGU1; J2235; PGL1; PSM1", "gene_names_refseq": "PGL1; PGU1; PSM1", "protein_names_uniprotkb": "Polygalacturonase; 3.2.1.15; PGase SM; PG; Pectinase", "protein_names_refseq": "endo-polygalacturonase", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR153W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "17322287;24374639;7804908;8641269;9682473", "class_list": "glycogene;glycosylhydrolase", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VWX2;E9P8V0", "ec_number_list": [], "go_molecular_function": "GO:0004650 polygalacturonase activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0045490 pectin catabolic process;GO:0071555 cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P47180-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.10100", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47183-1", "uniprot_id": [ { "id": "THI11_YEAST", "url": "https://www.uniprot.org/uniprot/P47183", "type": "external" } ], "mass": 38632.0, "length": 340, "protein_name": "4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI11", "gene_name": "THI11", "organism": "Yeast", "refseq_name": "4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase", "refseq_ac": [ { "id": "NP_012690", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012690", "type": "external" } ], "gene_names_uniprotkb": "THI11; J2250", "gene_names_refseq": "THI11", "protein_names_uniprotkb": "4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI11; 2.-.-.-; HMP-P synthase; Hydroxymethylpyrimidine phosphate synthase; Thiamine biosynthesis protein 11; Thiamine pyrimidine synthase", "protein_names_refseq": "4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR156C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12777485;14562106;24374639;8641269", "class_list": "", "function": "Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP). The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWX5", "ec_number_list": [ { "id": "2.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.-.-.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0106344 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP", "go_cellular_component": "", "go_biological_process": "GO:0009229 thiamine diphosphate biosynthetic process;GO:0009228 thiamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P47183-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47185-1", "uniprot_id": [ { "id": "HXT16_YEAST", "url": "https://www.uniprot.org/uniprot/P47185", "type": "external" } ], "mass": 62920.0, "length": 567, "protein_name": "Hexose transporter HXT16", "gene_name": "HXT16", "organism": "Yeast", "refseq_name": "hexose transporter HXT16", "refseq_ac": [ { "id": "NP_012692", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012692", "type": "external" } ], "gene_names_uniprotkb": "HXT16; J2260", "gene_names_refseq": "HLT3; HXT16", "protein_names_uniprotkb": "Hexose transporter HXT16", "protein_names_refseq": "hexose transporter HXT16", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR158W)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "24374639;8641269", "class_list": "", "function": "Probable glucose transporter., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWX6", "ec_number_list": [], "go_molecular_function": "GO:0005353 fructose transmembrane transporter activity;GO:0015578 mannose transmembrane transporter activity;GO:0005351 carbohydrate:proton symporter activity;GO:0055056 D-glucose transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0015797 mannitol transmembrane transport;GO:0008643 carbohydrate transport;GO:0008645 hexose transmembrane transport;GO:0015795 sorbitol transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P47185-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47187-1", "uniprot_id": [ { "id": "COS5_YEAST", "url": "https://www.uniprot.org/uniprot/P47187", "type": "external" } ], "mass": 45709.0, "length": 383, "protein_name": "Protein COS5", "gene_name": "COS5", "organism": "Yeast", "refseq_name": "Cos5p", "refseq_ac": [ { "id": "NP_012695", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012695", "type": "external" } ], "gene_names_uniprotkb": "COS5; J2410", "gene_names_refseq": "COS5", "protein_names_uniprotkb": "Protein COS5", "protein_names_refseq": "Cos5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR161C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;16847258;24374639;32597660;8641269", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWX9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005768 endosome;GO:0016020 membrane;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P47187-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47771-1", "uniprot_id": [ { "id": "ALDH2_YEAST", "url": "https://www.uniprot.org/uniprot/P47771", "type": "external" } ], "mass": 55188.0, "length": 506, "protein_name": "Aldehyde dehydrogenase [NAD(P)+] 1", "gene_name": "ALD2", "organism": "Yeast", "refseq_name": "aldehyde dehydrogenase (NAD(+)) ALD2", "refseq_ac": [ { "id": "NP_013893", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013893", "type": "external" } ], "gene_names_uniprotkb": "ALD2; ALD5; YM8520.19C", "gene_names_refseq": "ALD2", "protein_names_uniprotkb": "Aldehyde dehydrogenase [NAD(P)+] 1; 1.2.1.3", "protein_names_refseq": "aldehyde dehydrogenase (NAD(+)) ALD2", "tax_id": 559292, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); isolated microphthalmia 8 (Disease Ontology:DOID:0060841); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); alcohol-associated liver disease (Disease Ontology:DOID:0070658); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); heart disease (Disease Ontology:DOID:114); alcoholic liver cirrhosis (Disease Ontology:DOID:14018); alcohol use disorder (Disease Ontology:DOID:1574); pancreatic cancer (Disease Ontology:DOID:1793); brain infarction (Disease Ontology:DOID:3454); congenital diaphragmatic hernia (Disease Ontology:DOID:3827); liver disease (Disease Ontology:DOID:409); myocardial infarction (Disease Ontology:DOID:5844); hepatocellular carcinoma (Disease Ontology:DOID:684); type 2 diabetes mellitus (Disease Ontology:DOID:9352); diabetic neuropathy (Disease Ontology:DOID:9743); type 1 diabetes mellitus (Disease Ontology:DOID:9744); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (sce:YMR170C); (R-SCE-5365859)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "10407263;11914276;12586697;12794936;14562106;24374639;24909858;33491328;8801420;9169872", "class_list": "", "function": "Cytoplasmic aldehyde dehydrogenase involved in ethanol oxidation. Required for pantothenic acid production through the conversion of 3-aminopropanal to beta-alanine, an intermediate in pantothenic acid (vitamin B5) and coenzyme A (CoA) biosynthesis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 21, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZZ2", "ec_number_list": [ { "id": "1.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.5", "type": "external" }, { "id": "1.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.3", "type": "external" }, { "id": "1.2.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.64", "type": "external" } ], "go_molecular_function": "GO:0004029 aldehyde dehydrogenase (NAD+) activity;GO:0102244 3-aminopropanal dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0019483 beta-alanine biosynthetic process;GO:0006598 polyamine catabolic process;GO:0015940 pantothenate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P47771-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47976-1", "uniprot_id": [ { "id": "CTH1_YEAST", "url": "https://www.uniprot.org/uniprot/P47976", "type": "external" } ], "mass": 36772.0, "length": 325, "protein_name": "mRNA decay factor CTH1", "gene_name": "CTH1", "organism": "Yeast", "refseq_name": "putative mRNA-binding protein CTH1", "refseq_ac": [ { "id": "NP_010435", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010435", "type": "external" } ], "gene_names_uniprotkb": "CTH1; YD8358.07C", "gene_names_refseq": "CTH1", "protein_names_uniprotkb": "mRNA decay factor CTH1; Cysteine-three-histidine protein 1", "protein_names_refseq": "putative mRNA-binding protein CTH1", "tax_id": 559292, "disease": "breast cancer (Disease Ontology:DOID:1612); rheumatoid arthritis (Disease Ontology:DOID:7148)", "pathway": " (sce:YDR151C); (R-SCE-450385); (R-SCE-450513)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "17322287;18522836;24374639;30228242;8890739;9169867", "class_list": "", "function": "Binds to specific AU-rich elements (ARE) in the 3'-untranslated region of target mRNAs and promotes their degradation. In response to iron deficiency, promotes the decay of many mRNAs encoding proteins involved in iron-dependent pathways. Negatively regulates primarily iron-dependent mitochondrial processes including respiration and amino acid biosynthesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSD3", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis;GO:0000956 nuclear-transcribed mRNA catabolic process;GO:0070130 negative regulation of mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P47976-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P47988-1", "uniprot_id": [ { "id": "TEA1_YEAST", "url": "https://www.uniprot.org/uniprot/P47988", "type": "external" } ], "mass": 86833.0, "length": 759, "protein_name": "TY1 enhancer activator", "gene_name": "TEA1", "organism": "Yeast", "refseq_name": "Tea1p", "refseq_ac": [ { "id": "NP_014982", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014982", "type": "external" } ], "gene_names_uniprotkb": "TEA1; O6257", "gene_names_refseq": "TEA1", "protein_names_uniprotkb": "TY1 enhancer activator", "protein_names_refseq": "Tea1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR337W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "14562106;15665377;17330950;17467953;18407956;19779198;20702584;23749301;24374639;32597660;33481703;33491328;8524314;8896263;8948102;9169874", "class_list": "", "function": "TY1 element enhancer binding protein. Binds to the DNA sequence 5'-TCGGTGGTATTATTCCGA-3'., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W332", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0051285 cell cortex of cell tip", "go_biological_process": "GO:0006368 transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P47988-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48015-1", "uniprot_id": [ { "id": "GCST_YEAST", "url": "https://www.uniprot.org/uniprot/P48015", "type": "external" } ], "mass": 44469.0, "length": 400, "protein_name": "Aminomethyltransferase, mitochondrial", "gene_name": "GCV1", "organism": "Yeast", "refseq_name": "glycine decarboxylase subunit T", "refseq_ac": [ { "id": "NP_010302", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010302", "type": "external" } ], "gene_names_uniprotkb": "GCV1; YD9335.05C", "gene_names_refseq": "GCV1; GSD1", "protein_names_uniprotkb": "Aminomethyltransferase, mitochondrial; 2.1.2.10; GCVT; Glycine cleavage system T protein; Glycine decarboxylase complex subunit T", "protein_names_refseq": "glycine decarboxylase subunit T", "tax_id": 559292, "disease": "glycine encephalopathy 2 (Disease Ontology:DOID:0061001); glycine encephalopathy (Disease Ontology:DOID:9268)", "pathway": " (sce:YDR019C); (R-SCE-6783984)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "14562106;24374639;8896275;9047339;9169867", "class_list": "", "function": "The glycine cleavage system (glycine decarboxylase complex) catalyzes the degradation of glycine., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS05", "ec_number_list": [ { "id": "2.1.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.2.10", "type": "external" } ], "go_molecular_function": "GO:0008483 transaminase activity;GO:0004047 aminomethyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005960 glycine cleavage complex", "go_biological_process": "GO:0006730 one-carbon metabolic process;GO:0019464 glycine decarboxylation via glycine cleavage system;GO:0006546 glycine catabolic process;GO:0006544 glycine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P48015-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48239-1", "uniprot_id": [ { "id": "GSTO1_YEAST", "url": "https://www.uniprot.org/uniprot/P48239", "type": "external" } ], "mass": 41301.0, "length": 356, "protein_name": "Glutathione S-transferase omega-like 1", "gene_name": "GTO1", "organism": "Yeast", "refseq_name": "omega-class glutathione transferase", "refseq_ac": [ { "id": "NP_011670", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011670", "type": "external" } ], "gene_names_uniprotkb": "GTO1; G6664", "gene_names_refseq": "GTO1", "protein_names_uniprotkb": "Glutathione S-transferase omega-like 1; 1.8.5.1; 2.5.1.18; Glutathione-dependent dehydroascorbate reductase", "protein_names_refseq": "omega-class glutathione transferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR154C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "16709151;16936141;24374639;8585325;9169869", "class_list": "", "function": "Active as '1-Cys' thiol transferase against beta-hydroxyethyl disulfide (HED), as dehydroascorbate reductase and as dimethylarsinic acid reductase, while not active against the standard GST substrate 1-chloro-2,4-dinitrobenzene (CDNB)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUT4", "ec_number_list": [ { "id": "1.11.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.9", "type": "external" }, { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" }, { "id": "1.8.5.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.5.1", "type": "external" } ], "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0045174 glutathione dehydrogenase (ascorbate) activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005777 peroxisome", "go_biological_process": "GO:0006749 glutathione metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P48239-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48353-1", "uniprot_id": [ { "id": "HLJ1_YEAST", "url": "https://www.uniprot.org/uniprot/P48353", "type": "external" } ], "mass": 25008.0, "length": 224, "protein_name": "Protein HLJ1", "gene_name": "HLJ1", "organism": "Yeast", "refseq_name": "type I HSP40 co-chaperone HLJ1", "refseq_ac": [ { "id": "NP_013884", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013884", "type": "external" } ], "gene_names_uniprotkb": "HLJ1; YM8520.10", "gene_names_refseq": "HLJ1", "protein_names_uniprotkb": "Protein HLJ1", "protein_names_refseq": "type I HSP40 co-chaperone HLJ1", "tax_id": 559292, "disease": "Huntington's disease (Disease Ontology:DOID:12858)", "pathway": " (sce:YMR161W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562106;17330950;18407956;19779198;19795423;19823750;20702584;23749301;24374639;33481703;33491328;9169872", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZY3", "ec_number_list": [], "go_molecular_function": "GO:0001671 ATPase activator activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0036503 ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P48353-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48361-1", "uniprot_id": [ { "id": "ASK10_YEAST", "url": "https://www.uniprot.org/uniprot/P48361", "type": "external" } ], "mass": 126864.0, "length": 1146, "protein_name": "Activator of SKN7 protein 10", "gene_name": "ASK10", "organism": "Yeast", "refseq_name": "Ask10p", "refseq_ac": [ { "id": "NP_011611", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011611", "type": "external" } ], "gene_names_uniprotkb": "ASK10; RGC2", "gene_names_refseq": "ASK10; RGC2", "protein_names_uniprotkb": "Activator of SKN7 protein 10; Regulator of the glycerol channel 2", "protein_names_refseq": "Ask10p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR097W)", "pathway_count": 1, "publication_count": 30, "publication_id_list": "14555478;14562095;15665377;17287358;17330950;18407956;19684113;19779198;19795423;19823750;19956799;20489023;20702584;21126336;21177495;22218487;23749301;24298058;24374639;24909858;28265048;28270554;31208443;32597660;33229814;33481703;33491328;34965436;8904339;9169869", "class_list": "", "function": "Positive regulator of FPS1 glycerol channel required for the glycerol efflux. As a component of the RNA polymerase II holoenzyme, is required for SSN8 destruction in response to oxidative stress but not heat shock. Required for cell survival in response to heat shock independent of SSN8., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 9, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 9, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 9, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 58, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D6VUM9", "ec_number_list": [], "go_molecular_function": "GO:0016247 channel regulator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0034599 cellular response to oxidative stress;GO:0030163 protein catabolic process;GO:0090372 positive regulation of glycerol transport", "synthesized_glycan_count": 0, "hit_score": 4.1, "record_id": "P48361-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48362-1", "uniprot_id": [ { "id": "HGH1_YEAST", "url": "https://www.uniprot.org/uniprot/P48362", "type": "external" } ], "mass": 44951.0, "length": 394, "protein_name": "Co-chaperone protein HGH1", "gene_name": "HGH1", "organism": "Yeast", "refseq_name": "Hgh1p", "refseq_ac": [ { "id": "NP_011703", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011703", "type": "external" } ], "gene_names_uniprotkb": "HGH1; G7538", "gene_names_refseq": "HGH1", "protein_names_uniprotkb": "Co-chaperone protein HGH1; HMG1/2 protein homolog", "protein_names_refseq": "Hgh1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR187C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;22814378;24374639;30876804;30876805;33491328;9133739;9169869", "class_list": "", "function": "Co-chaperone involved in the folding of nascent eukaryotic elongation factor eEF2, an essential component of the translation machinery (PubMed:30876804). Recognizes a non-native conformation in the central domain of eEF2 and recruits the chaperonin-containing T-complex (TRiC) to the C-terminal region of the nascent polypeptide, preventing unproductive interactions and promoting efficient folding of the N-terminal GTPase domain (PubMed:30876804). 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6.1.1.17; GluRS; Glutamyl-tRNA synthetase", "protein_names_refseq": "glutamate--tRNA ligase MSE1", "tax_id": 559292, "disease": "combined oxidative phosphorylation deficiency 12 (Disease Ontology:DOID:0111493)", "pathway": " (sce:YOL033W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "14562106;24374639;33491328;9169874", "class_list": "", "function": "Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W232;Q08203", "ec_number_list": [ { "id": "6.1.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.17", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0000049 tRNA binding;GO:0004818 glutamate-tRNA ligase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006424 glutamyl-tRNA aminoacylation;GO:0032543 mitochondrial translation;GO:0070149 mitochondrial glutamyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P48525-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48526-1", "uniprot_id": [ { "id": "SYIM_YEAST", "url": "https://www.uniprot.org/uniprot/P48526", "type": "external" } ], "mass": 115794.0, "length": 1002, "protein_name": "Isoleucine--tRNA ligase, mitochondrial", "gene_name": "ISM1", "organism": "Yeast", "refseq_name": "isoleucine--tRNA ligase ISM1", "refseq_ac": [ { "id": "NP_015285", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015285", "type": "external" } ], "gene_names_uniprotkb": "ISM1; P7102.10", "gene_names_refseq": "ISM1", "protein_names_uniprotkb": "Isoleucine--tRNA ligase, mitochondrial; 6.1.1.5; IleRS; Isoleucyl-tRNA synthetase", "protein_names_refseq": "isoleucine--tRNA ligase ISM1", "tax_id": 559292, "disease": "mitochondrial metabolism disease (Disease Ontology:DOID:700)", "pathway": " (sce:YPL040C); (R-SCE-9837999)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "14562106;24374639;9169875", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W3X3", "ec_number_list": [ { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "7.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.2.2", "type": "external" }, { "id": "2.3.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.1", "type": "external" }, { "id": "4.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.2", "type": "external" }, { "id": "6.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.5", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "4.98.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.98.1.1", "type": "external" }, { "id": "4.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.3", "type": "external" }, { "id": "1.2.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.2", "type": "external" }, { "id": "1.1.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.37", "type": "external" }, { "id": "1.2.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.1", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "2.3.1.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.41", "type": "external" }, { "id": "1.2.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.4", "type": "external" }, { "id": "1.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.5", "type": "external" }, { "id": "2.3.3.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.10", "type": "external" } ], "go_molecular_function": "GO:0002161 aminoacyl-tRNA deacylase activity;GO:0004822 isoleucine-tRNA ligase activity;GO:0005524 ATP binding;GO:0000049 tRNA binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006428 isoleucyl-tRNA aminoacylation;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P48526-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48527-1", "uniprot_id": [ { "id": "SYYM_YEAST", "url": "https://www.uniprot.org/uniprot/P48527", "type": "external" } ], "mass": 55287.0, "length": 492, "protein_name": "Tyrosine--tRNA ligase, mitochondrial", "gene_name": "MSY1", "organism": "Yeast", "refseq_name": "tyrosine--tRNA ligase MSY1", "refseq_ac": [ { "id": "NP_015228", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015228", "type": "external" } ], "gene_names_uniprotkb": "MSY1; LPG11W", "gene_names_refseq": "MSY1", "protein_names_uniprotkb": "Tyrosine--tRNA ligase, mitochondrial; 6.1.1.1; TyrRS; Tyrosyl-tRNA synthetase", "protein_names_refseq": "tyrosine--tRNA ligase MSY1", "tax_id": 559292, "disease": "myopathy, lactic acidosis, and sideroblastic anemia 2 (Disease Ontology:DOID:0111186)", "pathway": " (sce:YPL097W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562095;14562106;14576278;24374639;9169875", "class_list": "", "function": "Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3R9", "ec_number_list": [ { "id": "6.1.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.1", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0004831 tyrosine-tRNA ligase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0005829 cytosol", "go_biological_process": "GO:0070184 mitochondrial tyrosyl-tRNA aminoacylation;GO:0043039 tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P48527-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48560-1", "uniprot_id": [ { "id": "TOS6_YEAST", "url": "https://www.uniprot.org/uniprot/P48560", "type": "external" } ], "mass": 10170.0, "length": 102, "protein_name": "Protein TOS6", "gene_name": "TOS6", "organism": "Yeast", "refseq_name": "Tos6p", "refseq_ac": [ { "id": "NP_014099", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014099", "type": "external" } ], "gene_names_uniprotkb": "TOS6; 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N0466; PAL2", "gene_names_refseq": "PAL2; RIM21", "protein_names_uniprotkb": "pH-response regulator protein palH/RIM21; Regulator of IME2 protein 21", "protein_names_refseq": "Rim21p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL294C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10821185;16847258;18407956;19779198;24374639;32597660;33481703;33491328;8553702;9169873", "class_list": "", "function": "Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH (By similarity). Required for growth at alkaline pH., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0P9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane", "go_biological_process": "GO:0071469 cellular response to alkaline pH;GO:0071467 cellular response to pH;GO:0044088 regulation of vacuole organization;GO:0001403 invasive growth in response to glucose limitation;GO:0009272 fungal-type cell wall biogenesis", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P48565-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48567-1", "uniprot_id": [ { "id": "PUS4_YEAST", "url": "https://www.uniprot.org/uniprot/P48567", "type": "external" } ], "mass": 45273.0, "length": 403, "protein_name": "tRNA pseudouridine synthase 4", "gene_name": "PUS4", "organism": "Yeast", "refseq_name": "pseudouridine synthase PUS4", "refseq_ac": [ { "id": "NP_014107", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014107", "type": "external" } ], "gene_names_uniprotkb": "PUS4; N0480", "gene_names_refseq": "PUS4", "protein_names_uniprotkb": "tRNA pseudouridine synthase 4; 5.4.99.25; Psi55 synthase; tRNA pseudouridine(55) synthase; tRNA pseudouridylate synthase 4; tRNA-uridine isomerase 4", "protein_names_refseq": "pseudouridine synthase PUS4", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL292W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562106;18407956;21126336;24374639;25219674;33481703;33491328;8553702;9169873;9358157", "class_list": "", "function": "Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs (PubMed:9358157). Also catalyzes pseudouridylation of mRNAs with the consensus sequence 5'-GGUUCRA-3' (PubMed:25219674)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0Q1", "ec_number_list": [ { "id": "5.4.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.99.-", "type": "external" }, { "id": "5.4.99.25", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.99.25", "type": "external" }, { "id": "5.4.99.27", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.99.27", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0009982 pseudouridine synthase activity;GO:0160148 tRNA pseudouridine(55) synthase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006400 tRNA modification;GO:1990481 mRNA pseudouridine synthesis", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P48567-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48570-1", "uniprot_id": [ { "id": "HOSC_YEAST", "url": "https://www.uniprot.org/uniprot/P48570", "type": "external" } ], "mass": 47099.0, "length": 428, "protein_name": "Homocitrate synthase, cytosolic isozyme", "gene_name": "LYS20", "organism": "Yeast", "refseq_name": "homocitrate synthase LYS20", "refseq_ac": [ { "id": "NP_010099", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010099", "type": "external" } ], "gene_names_uniprotkb": "LYS20; D1298", "gene_names_refseq": "LYS20", "protein_names_uniprotkb": "Homocitrate synthase, cytosolic isozyme; 2.3.3.14; HCS", "protein_names_refseq": "homocitrate synthase LYS20", "tax_id": 559292, "disease": "3-hydroxy-3-methylglutaryl-CoA lyase deficiency (Disease Ontology:DOID:0070541); amino acid metabolic disorder (Disease Ontology:DOID:9252)", "pathway": " (sce:YDL182W)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "14562106;15665377;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21177495;22218487;23749301;24374639;32597660;33481703;33491328;8533471;8923736;9169867", "class_list": "", "function": "Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRH0", "ec_number_list": [ { "id": "2.3.3.14", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.14", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004410 homocitrate synthase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006281 DNA repair;GO:0019878 lysine biosynthetic process via aminoadipic acid", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P48570-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P48589-1", "uniprot_id": [ { "id": "RS12_YEAST", "url": "https://www.uniprot.org/uniprot/P48589", "type": "external" } ], "mass": 15472.0, "length": 143, "protein_name": "Small ribosomal subunit protein eS12", "gene_name": "RPS12", "organism": "Yeast", "refseq_name": "40S ribosomal protein eS12 RPS12", "refseq_ac": [ { "id": "NP_015014", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015014", "type": "external" } ], "gene_names_uniprotkb": "RPS12", "gene_names_refseq": "RPS12", "protein_names_uniprotkb": "Small ribosomal subunit protein eS12; 40S ribosomal protein S12", "protein_names_refseq": "40S ribosomal protein eS12 RPS12", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR369C); (R-SCE-156827); (R-SCE-1799339); (R-SCE-6791226); (R-SCE-72649); (R-SCE-72689); (R-SCE-72695); (R-SCE-72702); (R-SCE-72706); (R-SCE-975956); (R-SCE-975957); (R-SCE-9954714)", "pathway_count": 12, "publication_count": 16, "publication_id_list": "17287358;18407956;19684113;19779198;19795423;19823750;22096102;22106047;22218487;24374639;24524803;33481703;33491328;8649984;9169874;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W362;Q02545", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:1990145 maintenance of translational fidelity;GO:0002181 cytoplasmic translation;GO:0042274 ribosomal small subunit biogenesis;GO:0030490 maturation of SSU-rRNA;GO:0000028 ribosomal small subunit assembly", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P48589-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P49089-1", "uniprot_id": [ { "id": "ASNS1_YEAST", "url": "https://www.uniprot.org/uniprot/P49089", "type": "external" } ], "mass": 64470.0, "length": 572, "protein_name": "Asparagine synthetase [glutamine-hydrolyzing] 1", "gene_name": "ASN1", "organism": "Yeast", "refseq_name": "asparagine synthase (glutamine-hydrolyzing) 1", "refseq_ac": [ { "id": "NP_015471", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015471", "type": "external" } ], "gene_names_uniprotkb": "ASN1; P9659.3", "gene_names_refseq": "ASN1", "protein_names_uniprotkb": "Asparagine synthetase [glutamine-hydrolyzing] 1; 6.3.5.4; Glutamine-dependent asparagine synthetase 1", "protein_names_refseq": "asparagine synthase (glutamine-hydrolyzing) 1", "tax_id": 559292, "disease": "hepatocellular carcinoma (Disease Ontology:DOID:684); retinal degeneration (Disease Ontology:DOID:8466)", "pathway": " (sce:YPR145W); (R-SCE-8963693)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "17563356;18407956;19795423;19823750;22814378;23749301;24374639;33481703;33491328;8951815;9169875", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 24, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4E2", "ec_number_list": [ { "id": "6.3.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.5.4", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0097268 cytoophidium", "go_biological_process": "GO:0070981 L-asparagine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P49089-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P49090-1", "uniprot_id": [ { "id": "ASNS2_YEAST", "url": "https://www.uniprot.org/uniprot/P49090", "type": "external" } ], "mass": 64593.0, "length": 572, "protein_name": "Asparagine synthetase [glutamine-hydrolyzing] 2", "gene_name": "ASN2", "organism": "Yeast", "refseq_name": "asparagine synthase (glutamine-hydrolyzing) 2", "refseq_ac": [ { "id": "NP_011640", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011640", "type": "external" } ], "gene_names_uniprotkb": "ASN2; G6358", "gene_names_refseq": "ASN2", "protein_names_uniprotkb": "Asparagine synthetase [glutamine-hydrolyzing] 2; 6.3.5.4; Glutamine-dependent asparagine synthetase 2", "protein_names_refseq": "asparagine synthase (glutamine-hydrolyzing) 2", "tax_id": 559292, "disease": "hepatocellular carcinoma (Disease Ontology:DOID:684); retinal degeneration (Disease Ontology:DOID:8466)", "pathway": " (sce:YGR124W); (R-SCE-8963693)", "pathway_count": 2, "publication_count": 15, "publication_id_list": "14562106;17287358;17322287;17330950;17563356;18407956;19779198;21126336;23749301;24374639;32597660;33481703;33491328;9046098;9169869", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUQ6;E9P8Y0", "ec_number_list": [ { "id": "6.3.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.5.4", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0070981 L-asparagine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P49090-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P49167-1", "uniprot_id": [ { "id": "RL38_YEAST", "url": "https://www.uniprot.org/uniprot/P49167", "type": "external" } ], "mass": 8827.0, "length": 78, "protein_name": "Large ribosomal subunit protein eL38", "gene_name": "RPL38", "organism": "Yeast", "refseq_name": "60S ribosomal protein eL38 RPL38", "refseq_ac": [ { "id": "NP_013429", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013429", "type": "external" } ], "gene_names_uniprotkb": "RPL38; L8543.2", "gene_names_refseq": "RPL38", "protein_names_uniprotkb": "Large ribosomal subunit protein eL38; 60S ribosomal protein L38", "protein_names_refseq": "60S ribosomal protein eL38 RPL38", "tax_id": 559292, "disease": "otitis media (Disease Ontology:DOID:10754)", "pathway": " (sce:YLR325C); (R-SCE-156827); (R-SCE-1799339); (R-SCE-72689); (R-SCE-72706); (R-SCE-975956); (R-SCE-975957); (R-SCE-9954709); (R-SCE-9954714)", "pathway_count": 9, "publication_count": 17, "publication_id_list": "10601260;14562095;14562106;15665377;18407956;19779198;21109664;22096102;23749301;24374639;24524803;30516470;32597660;33481703;33491328;9169871;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYW7", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation;GO:0022618 protein-RNA complex assembly", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P49167-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P49954-1", "uniprot_id": [ { "id": "NIT3_YEAST", "url": "https://www.uniprot.org/uniprot/P49954", "type": "external" } ], "mass": 32549.0, "length": 291, "protein_name": "Omega-amidase NIT3", "gene_name": "NIT3", "organism": "Yeast", "refseq_name": "putative hydrolase", "refseq_ac": [ { "id": "NP_013455", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013455", "type": "external" } ], "gene_names_uniprotkb": "NIT3; L9638.5", "gene_names_refseq": "NIT3", "protein_names_uniprotkb": "Omega-amidase NIT3; 3.5.1.3; Nitrilase homolog 2", "protein_names_refseq": "putative hydrolase", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR351C); (R-SCE-6798695)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "10959838;12833551;14562106;18407956;23749301;24374639;28373563;33491328;9169871", "class_list": "", "function": "Possesses omega-amidase activity (PubMed:28373563). The role of omega-amidase is to remove potentially toxic intermediates by converting 2-oxoglutaramate and 2-oxosuccinamate to biologically useful 2-oxoglutarate and oxaloacetate, respectively., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYY9;Q71SP9", "ec_number_list": [ { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "3.4.23.25", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.23.25", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "2.3.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.16", "type": "external" }, { "id": "5.4.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "3.5.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.3", "type": "external" }, { "id": "3.2.1.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.14", "type": "external" }, { "id": "3.5.4.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5", "type": "external" }, { "id": "3.4.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.-", "type": "external" }, { "id": "3.3.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.3.2.10", "type": "external" } ], "go_molecular_function": "GO:0050152 omega-amidase activity;GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0006528 asparagine metabolic process;GO:0006107 oxaloacetate metabolic process;GO:0006541 glutamine metabolic process;GO:0043605 amide catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P49954-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50077-1", "uniprot_id": [ { "id": "CCH1_YEAST", "url": "https://www.uniprot.org/uniprot/P50077", "type": "external" } ], "mass": 234599.0, "length": 2039, "protein_name": "Calcium-channel protein CCH1", "gene_name": "CCH1", "organism": "Yeast", "refseq_name": "calcium channel protein CCH1", "refseq_ac": [ { "id": "NP_011733", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011733", "type": "external" } ], "gene_names_uniprotkb": "CCH1; G8501", "gene_names_refseq": "CCH1", "protein_names_uniprotkb": "Calcium-channel protein CCH1", "protein_names_refseq": "calcium channel protein CCH1", "tax_id": 559292, "disease": "arrhythmogenic right ventricular cardiomyopathy (Disease Ontology:DOID:0050431); congenital stationary night blindness (Disease Ontology:DOID:0050534); hereditary sensory and autonomic neuropathy (Disease Ontology:DOID:0050548); Aland Island eye disease (Disease Ontology:DOID:0050630); familial atrial fibrillation (Disease Ontology:DOID:0050650); alcohol dependence (Disease Ontology:DOID:0050741); hereditary ataxia (Disease Ontology:DOID:0050951); generalized epilepsy with febrile seizures plus (Disease Ontology:DOID:0060170); Timothy syndrome (Disease Ontology:DOID:0060173); episodic ataxia type 9 (Disease Ontology:DOID:0060965); hereditary sensory and autonomic neuropathy type 7 (Disease Ontology:DOID:0070149); absence epilepsy (Disease Ontology:DOID:0070309); developmental and epileptic encephalopathy 6B (Disease Ontology:DOID:0070379); neurodevelopmental disorder with hypotonia, language delay, and skeletal defects with or without seizures (Disease Ontology:DOID:0070536); developmental and epileptic encephalopathy 62 (Disease Ontology:DOID:0080420); developmental and epileptic encephalopathy 11 (Disease Ontology:DOID:0080421); Dravet syndrome (Disease Ontology:DOID:0080422); developmental and epileptic encephalopathy 13 (Disease Ontology:DOID:0080445); congenital limbs-face contractures-hypotonia-developmental delay syndrome (Disease Ontology:DOID:0081048); benign familial infantile seizures 3 (Disease Ontology:DOID:0081116); benign familial infantile seizures 5 (Disease Ontology:DOID:0081118); congenital myopathy 18 (Disease Ontology:DOID:0081350); congenital myopathy 22A (Disease Ontology:DOID:0081354); congenital myopathy 22B (Disease Ontology:DOID:0081355); familial focal epilepsy with variable foci 4 (Disease Ontology:DOID:0081424); Brugada syndrome 1 (Disease Ontology:DOID:0110218); Brugada syndrome 3 (Disease Ontology:DOID:0110220); dilated cardiomyopathy 1E (Disease Ontology:DOID:0110433); long QT syndrome 3 (Disease Ontology:DOID:0110646); long QT syndrome 8 (Disease Ontology:DOID:0110649); congenital myasthenic syndrome 16 (Disease Ontology:DOID:0110682); congenital stationary night blindness 2A (Disease Ontology:DOID:0110871); X-linked cone-rod dystrophy 3 (Disease Ontology:DOID:0111007); progressive familial heart block type IA (Disease Ontology:DOID:0111074); familial hemiplegic migraine 1 (Disease Ontology:DOID:0111181); familial hemiplegic migraine 3 (Disease Ontology:DOID:0111183); generalized epilepsy with febrile seizures plus 2 (Disease Ontology:DOID:0111294); paroxysmal extreme pain disorder (Disease Ontology:DOID:0111537); paramyotonia congenita of Von Eulenburg (Disease Ontology:DOID:0111538); familial episodic pain syndrome 2 (Disease Ontology:DOID:0111730); familial episodic pain syndrome 3 (Disease Ontology:DOID:0111731); sciatic neuropathy (Disease Ontology:DOID:11446); Duchenne muscular dystrophy (Disease Ontology:DOID:11723); sick sinus syndrome (Disease Ontology:DOID:13884); hyperkalemic periodic paralysis (Disease Ontology:DOID:14451); hypokalemic periodic paralysis (Disease Ontology:DOID:14452); congenital heart disease (Disease Ontology:DOID:1682); epilepsy (Disease Ontology:DOID:1826); long QT syndrome (Disease Ontology:DOID:2843); schizophrenia (Disease Ontology:DOID:5419); migraine (Disease Ontology:DOID:6364); malignant hyperthermia (Disease Ontology:DOID:8545); sudden infant death syndrome (Disease Ontology:DOID:9007); erythromelalgia (Disease Ontology:DOID:9240); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (sce:YGR217W); (R-SCE-445355)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "10958666;16950930;17287358;18407956;19684113;23749301;24374639;32597660;33481703;33491328;8701610;9169869;9290212;9343395", "class_list": "", "function": "Voltage-gated, high-affinity calcium channel that functions together with MID1 to mediate calcium entry into cells (PubMed:10958666, PubMed:9343395). Required during conditions of environmental stress (PubMed:10958666, PubMed:9343395)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 20, "predicted_n_glycosites": 19, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 20, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 55, "glyco_site_count": 20, "binding_glycan_count": 0, "secondary_ac_list": "D6VV00", "ec_number_list": [], "go_molecular_function": "GO:0005262 calcium channel activity;GO:0005509 calcium ion binding;GO:0005245 voltage-gated calcium channel activity;GO:0008331 high voltage-gated calcium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005891 voltage-gated calcium channel complex", "go_biological_process": "GO:0006816 calcium ion transport;GO:0098703 calcium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P50077-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0000000011001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50078-1", "uniprot_id": [ { "id": "TOS2_YEAST", "url": "https://www.uniprot.org/uniprot/P50078", "type": "external" } ], "mass": 69471.0, "length": 622, "protein_name": "Protein TOS2", "gene_name": "TOS2", "organism": "Yeast", "refseq_name": "Tos2p", "refseq_ac": [ { "id": "NP_011737", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011737", "type": "external" } ], "gene_names_uniprotkb": "TOS2; G8523", "gene_names_refseq": "TOS2", "protein_names_uniprotkb": "Protein TOS2; Target of SBF 2", "protein_names_refseq": "Tos2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR221C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562106;14574415;14872283;23749301;24374639;33481703;33491328;8701610;9169869", "class_list": "", "function": "Seems to be involved in the anchoring of CDC24 to the membrane of polarized growth sites., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV03", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0030427 site of polarized growth;GO:0000131 incipient cellular bud site;GO:0005933 cellular bud;GO:0005934 cellular bud tip;GO:0005935 cellular bud neck", "go_biological_process": "GO:0032507 maintenance of protein location in cell;GO:1902413 negative regulation of mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P50078-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50080-1", "uniprot_id": [ { "id": "AZR1_YEAST", "url": "https://www.uniprot.org/uniprot/P50080", "type": "external" } ], "mass": 67169.0, "length": 613, "protein_name": "Azole resistance protein 1", "gene_name": "AZR1", "organism": "Yeast", "refseq_name": "azole transporter", "refseq_ac": [ { "id": "NP_011740", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011740", "type": "external" } ], "gene_names_uniprotkb": "AZR1; G8537", "gene_names_refseq": "AZR1", "protein_names_uniprotkb": "Azole resistance protein 1", "protein_names_refseq": "azole transporter", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR224W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11113970;12529331;16847258;24374639;8701610;9169869", "class_list": "", "function": "Transporter protein required for adaptation to high stress imposed by low-chain organic acids, in particular by acetic acid, and for resistance to azoles, especially to ketoconazole and fluconazole., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV06", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:1901474 azole transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0055085 transmembrane transport;GO:0045117 azole transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P50080-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50104-1", "uniprot_id": [ { "id": "STB4_YEAST", "url": "https://www.uniprot.org/uniprot/P50104", "type": "external" } ], "mass": 109825.0, "length": 949, "protein_name": "Probable transcriptional regulatory protein STB4", "gene_name": "STB4", "organism": "Yeast", "refseq_name": "Stb4p", "refseq_ac": [ { "id": "NP_013732", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013732", "type": "external" } ], "gene_names_uniprotkb": "STB4; YM9711.08", "gene_names_refseq": "STB4", "protein_names_uniprotkb": "Probable transcriptional regulatory protein STB4", "protein_names_refseq": "Stb4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR019W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;15665377;23749301;24374639;33491328;9169872;9393435", "class_list": "", "function": "Binds to SIN3., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZJ3", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P50104-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50109-1", "uniprot_id": [ { "id": "PSP2_YEAST", "url": "https://www.uniprot.org/uniprot/P50109", "type": "external" } ], "mass": 65584.0, "length": 593, "protein_name": "Protein PSP2", "gene_name": "PSP2", "organism": "Yeast", "refseq_name": "Psp2p", "refseq_ac": [ { "id": "NP_013695", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013695", "type": "external" } ], "gene_names_uniprotkb": "PSP2; MRS15; YM9571.01", "gene_names_refseq": "MRS15; PSP2", "protein_names_uniprotkb": "Protein PSP2; Mitochondrial regulator of splicing 15; Polymerase suppressor protein 2", "protein_names_refseq": "Psp2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YML017W); (R-SCE-6791226)", "pathway_count": 2, "publication_count": 30, "publication_id_list": "12844361;14562095;14562106;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23222640;23749301;24374639;26046779;30516470;31208443;32597660;33229814;33481703;33491328;33856219;34965436;8252639;9169872;9529527", "class_list": "", "function": "DNA polymerase alpha mutation suppressor. Suppressor of group II intron splicing defects of a mutation in MRS2. May play a role in mitochondrial mRNA splicing., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 6, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 6, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 6, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VZF7;Q07170;Q870H3", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000932 P-body;GO:0010494 cytoplasmic stress granule;GO:0000172 ribonuclease MRP complex", "go_biological_process": "GO:0001682 tRNA 5'-leader removal", "synthesized_glycan_count": 0, "hit_score": 3.8, "record_id": "P50109-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50112-1", "uniprot_id": [ { "id": "KNH1_YEAST", "url": "https://www.uniprot.org/uniprot/P50112", "type": "external" } ], "mass": 29753.0, "length": 268, "protein_name": "Cell wall synthesis protein KNH1", "gene_name": "KNH1", "organism": "Yeast", "refseq_name": "Knh1p", "refseq_ac": [ { "id": "NP_010234", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010234", "type": "external" } ], "gene_names_uniprotkb": "KNH1", "gene_names_refseq": "KNH1", "protein_names_uniprotkb": "Cell wall synthesis protein KNH1", "protein_names_refseq": "Knh1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL049C)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "24374639;8810042;9169867", "class_list": "", "function": "Involved in cell wall beta(1->6) glucan synthesis., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VRU6;Q07354", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0042546 cell wall biogenesis;GO:0006078 (1->6)-beta-D-glucan biosynthetic process;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P50112-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50113-1", "uniprot_id": [ { "id": "LYS5_YEAST", "url": "https://www.uniprot.org/uniprot/P50113", "type": "external" } ], "mass": 30683.0, "length": 272, "protein_name": "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "gene_name": "LYS5", "organism": "Yeast", "refseq_name": "holo-[acyl-carrier-protein] synthase", "refseq_ac": [ { "id": "NP_011361", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011361", "type": "external" } ], "gene_names_uniprotkb": "LYS5; G1867", "gene_names_refseq": "LYS5", "protein_names_uniprotkb": "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; 2.7.8.7; AASD-PPT", "protein_names_refseq": "holo-[acyl-carrier-protein] synthase", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL154C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10320345;14562106;17322287;24374639;8585324;8654981;9169869", "class_list": "", "function": "Catalyzes the transfer of a 4'-phosphopantetheine moiety from coenzyme A to a serine residue of acceptor proteins, such as alpha-aminoadipate reductase. Necessary for alpha-aminoadipate reductase activity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTZ7", "ec_number_list": [ { "id": "2.7.8.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.7", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0008897 holo-[acyl-carrier-protein] synthase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0019878 lysine biosynthetic process via aminoadipic acid", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P50113-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50273-1", "uniprot_id": [ { "id": "ATP22_YEAST", "url": "https://www.uniprot.org/uniprot/P50273", "type": "external" } ], "mass": 79756.0, "length": 684, "protein_name": "Mitochondrial translation factor ATP22", "gene_name": "ATP22", "organism": "Yeast", "refseq_name": "Atp22p", "refseq_ac": [ { "id": "NP_010637", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010637", "type": "external" } ], "gene_names_uniprotkb": "ATP22; D9476.9; TCM10", "gene_names_refseq": "ATP22; TCM10", "protein_names_uniprotkb": "Mitochondrial translation factor ATP22", "protein_names_refseq": "Atp22p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR350C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12646576;17110482;24374639;33229814;9169867", "class_list": "", "function": "Translation factor specific for subunit 6 of the mitochondrial ATPase. Required for assembly of the CF(0) component of the ATPase., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VSY0", "ec_number_list": [], "go_molecular_function": "GO:0045182 translation regulator activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0070131 positive regulation of mitochondrial translation;GO:0070071 proton-transporting two-sector ATPase complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P50273-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50276-1", "uniprot_id": [ { "id": "MUP1_YEAST", "url": "https://www.uniprot.org/uniprot/P50276", "type": "external" } ], "mass": 63221.0, "length": 574, "protein_name": "High-affinity methionine permease", "gene_name": "MUP1", "organism": "Yeast", "refseq_name": "Mup1p", "refseq_ac": [ { "id": "NP_011569", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011569", "type": "external" } ], "gene_names_uniprotkb": "MUP1", "gene_names_refseq": "MUP1", "protein_names_uniprotkb": "High-affinity methionine permease", "protein_names_refseq": "Mup1p", "tax_id": 559292, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); large cell neuroendocrine carcinoma (Disease Ontology:DOID:0050872); autism spectrum disorder (Disease Ontology:DOID:0060041); lysinuric protein intolerance (Disease Ontology:DOID:0060439); adenoid cystic carcinoma (Disease Ontology:DOID:0080202); lung pleomorphic carcinoma (Disease Ontology:DOID:0080899); sensorineural hearing loss (Disease Ontology:DOID:10003); stomach cancer (Disease Ontology:DOID:10534); esophageal carcinoma (Disease Ontology:DOID:1107); opioid abuse (Disease Ontology:DOID:11206); esophagitis (Disease Ontology:DOID:11963); rectum adenocarcinoma (Disease Ontology:DOID:1996); colon cancer (Disease Ontology:DOID:219); platelet storage pool deficiency (Disease Ontology:DOID:2223); transitional cell carcinoma (Disease Ontology:DOID:2671); glioblastoma (Disease Ontology:DOID:3068); malignant astrocytoma (Disease Ontology:DOID:3069); high grade glioma (Disease Ontology:DOID:3070); extrahepatic bile duct adenocarcinoma (Disease Ontology:DOID:3495); gastric adenocarcinoma (Disease Ontology:DOID:3717); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); Hermansky-Pudlak syndrome (Disease Ontology:DOID:3753); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); bile duct adenocarcinoma (Disease Ontology:DOID:4896); bile duct carcinoma (Disease Ontology:DOID:4897); cholangiocarcinoma (Disease Ontology:DOID:4947); hepatocellular carcinoma (Disease Ontology:DOID:684); malignant pleural mesothelioma (Disease Ontology:DOID:7474); colorectal cancer (Disease Ontology:DOID:9256); cystinuria (Disease Ontology:DOID:9266)", "pathway": " (sce:YGR055W); (R-SCE-352230)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "16273108;16847258;17330950;17563356;18407956;19779198;22106047;23749301;24374639;33481703;33491328;34965436;8893857;9169869", "class_list": "", "function": "High affinity permease for methionine., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 36, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUJ0;Q45U31", "ec_number_list": [], "go_molecular_function": "GO:0015179 L-amino acid transmembrane transporter activity;GO:0000102 L-methionine secondary active transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0003333 amino acid transmembrane transport;GO:0042883 cysteine transport;GO:0015821 methionine transport;GO:0000101 sulfur amino acid transport;GO:1903692 methionine import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P50276-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50277-1", "uniprot_id": [ { "id": "BIOA_YEAST", "url": "https://www.uniprot.org/uniprot/P50277", "type": "external" } ], "mass": 53709.0, "length": 480, "protein_name": "Adenosylmethionine-8-amino-7-oxononanoate aminotransferase", "gene_name": "BIO3", "organism": "Yeast", "refseq_name": "adenosylmethionine-8-amino-7-oxononanoate transaminase", "refseq_ac": [ { "id": "NP_014456", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014456", "type": "external" } ], "gene_names_uniprotkb": "BIO3; N3510", "gene_names_refseq": "BIO3", "protein_names_uniprotkb": "Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; 2.6.1.62; 7,8-diamino-pelargonic acid aminotransferase; DAPA AT; DAPA aminotransferase; Diaminopelargonic acid synthase", "protein_names_refseq": "adenosylmethionine-8-amino-7-oxononanoate transaminase", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR058W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10333520;16269718;17322287;23749301;24374639;33491328;9169873", "class_list": "", "function": "Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA) (PubMed:10333520). It is the only aminotransferase known to utilize SAM as an amino donor (PubMed:10333520)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1N3;E9P967;Q4R1J0", "ec_number_list": [ { "id": "2.6.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.62", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004015 adenosylmethionine-8-amino-7-oxononanoate transaminase activity;GO:0004141 dethiobiotin synthase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0009102 biotin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P50277-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50873-1", "uniprot_id": [ { "id": "MRK1_YEAST", "url": "https://www.uniprot.org/uniprot/P50873", "type": "external" } ], "mass": 57819.0, "length": 501, "protein_name": "Serine/threonine-protein kinase MRK1", "gene_name": "MRK1", "organism": "Yeast", "refseq_name": "putative serine/threonine protein kinase MRK1", "refseq_ac": [ { "id": "NP_010204", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010204", "type": "external" } ], "gene_names_uniprotkb": "MRK1", "gene_names_refseq": "MRK1", "protein_names_uniprotkb": "Serine/threonine-protein kinase MRK1; 2.7.11.1", "protein_names_refseq": "putative serine/threonine protein kinase MRK1", "tax_id": 559292, "disease": "diabetic encephalopathy (Disease Ontology:DOID:0050850); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); Parkinsonism (Disease Ontology:DOID:0080855); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); heart disease (Disease Ontology:DOID:114); sciatic neuropathy (Disease Ontology:DOID:11446); Parkinson's disease (Disease Ontology:DOID:14330); depressive disorder (Disease Ontology:DOID:1596); status epilepticus (Disease Ontology:DOID:1824); colon cancer (Disease Ontology:DOID:219); endometrial carcinoma (Disease Ontology:DOID:2871); substance-related disorder (Disease Ontology:DOID:303); bipolar disorder (Disease Ontology:DOID:3312); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); middle cerebral artery infarction (Disease Ontology:DOID:3525); schizophrenia (Disease Ontology:DOID:5419); myocardial infarction (Disease Ontology:DOID:5844); vascular dementia (Disease Ontology:DOID:8725); degenerative disc disease (Disease Ontology:DOID:90); type 2 diabetes mellitus (Disease Ontology:DOID:9352); acute myocardial infarction (Disease Ontology:DOID:9408)", "pathway": " (sce:YDL079C); (R-SCE-3371453); (R-SCE-69601); (R-SCE-9856649)", "pathway_count": 4, "publication_count": 7, "publication_id_list": "19779198;20489023;23749301;24374639;33491328;7695629;9169867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 23, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRS0;Q07470", "ec_number_list": [ { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.1.26.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.26.-", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.67", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction;GO:0030154 cell differentiation;GO:0042176 regulation of protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P50873-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50896-1", "uniprot_id": [ { "id": "PSP1_YEAST", "url": "https://www.uniprot.org/uniprot/P50896", "type": "external" } ], "mass": 95348.0, "length": 841, "protein_name": "Protein PSP1", "gene_name": "PSP1", "organism": "Yeast", "refseq_name": "Psp1p", "refseq_ac": [ { "id": "NP_010793", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010793", "type": "external" } ], "gene_names_uniprotkb": "PSP1; D9719.11; GIN5", "gene_names_refseq": "GIN5; PSP1", "protein_names_uniprotkb": "Protein PSP1; Growth inhibitory protein 5; Polymerase suppressor protein 1", "protein_names_refseq": "Psp1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR505C)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "14562095;14562106;14576278;17330950;17563356;18407956;19779198;20702584;23749301;24374639;30516470;32597660;33229814;33481703;33491328;9169867;9529527", "class_list": "", "function": "DNA polymerase alpha mutation suppressor., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 16, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VTC7", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0000932 P-body", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P50896-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50944-1", "uniprot_id": [ { "id": "AVT4_YEAST", "url": "https://www.uniprot.org/uniprot/P50944", "type": "external" } ], "mass": 80026.0, "length": 713, "protein_name": "Vacuolar amino acid transporter 4", "gene_name": "AVT4", "organism": "Yeast", "refseq_name": "Avt4p", "refseq_ac": [ { "id": "NP_014298", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014298", "type": "external" } ], "gene_names_uniprotkb": "AVT4; N2185", "gene_names_refseq": "AVT4", "protein_names_uniprotkb": "Vacuolar amino acid transporter 4", "protein_names_refseq": "Avt4p", "tax_id": 559292, "disease": "iminoglycinuria (Disease Ontology:DOID:0112265)", "pathway": " (sce:YNL101W)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "11274162;16847258;17287358;17330950;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;24374639;32597660;33481703;33491328;8701612;9169873", "class_list": "", "function": "Involved in amino acid efflux from the vacuole to the cytoplasm. Capable of transporting large neutral amino acids including tyrosine, glutamine, asparagine, isoleucine and leucine., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 27, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W178", "ec_number_list": [], "go_molecular_function": "GO:0015188 L-isoleucine transmembrane transporter activity;GO:0015186 L-glutamine transmembrane transporter activity;GO:0005302 L-tyrosine transmembrane transporter activity", "go_cellular_component": "GO:0005774 vacuolar membrane;GO:0000329 fungal-type vacuole membrane;GO:0000324 fungal-type vacuole;GO:1990816 vacuole-mitochondrion membrane contact site", "go_biological_process": "GO:0003333 amino acid transmembrane transport;GO:0032974 amino acid transmembrane export from vacuole", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P50944-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P51401-1", "uniprot_id": [ { "id": "RL9B_YEAST", "url": "https://www.uniprot.org/uniprot/P51401", "type": "external" } ], "mass": 21657.0, "length": 191, "protein_name": "Large ribosomal subunit protein uL6B", "gene_name": "RPL9B", "organism": "Yeast", "refseq_name": "60S ribosomal protein uL6 RPL9B", "refseq_ac": [ { "id": "NP_014332", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014332", "type": "external" } ], "gene_names_uniprotkb": "RPL9B; N2406; RPL8B; YNL2406W", "gene_names_refseq": "RPL9B", "protein_names_uniprotkb": "Large ribosomal subunit protein uL6B; 60S ribosomal protein L9-B; L8; RP24; YL11", "protein_names_refseq": "60S ribosomal protein uL6 RPL9B", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL067W); (R-SCE-156827); (R-SCE-1799339); (R-SCE-72689); (R-SCE-72706); (R-SCE-975956); (R-SCE-975957); (R-SCE-9954709); (R-SCE-9954714)", "pathway_count": 9, "publication_count": 10, "publication_id_list": "14562095;14562106;17322287;22096102;24374639;24524803;8533472;8701611;9169873;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1B3", "ec_number_list": [], "go_molecular_function": "GO:0019843 rRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P51401-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P51998-1", "uniprot_id": [ { "id": "RL4P_YEAST", "url": "https://www.uniprot.org/uniprot/P51998", "type": "external" } ], "mass": 31970.0, "length": 286, "protein_name": "Large ribosomal subunit protein uL4m", "gene_name": "YML6", "organism": "Yeast", "refseq_name": "mitochondrial 54S ribosomal protein uL4m YML6", "refseq_ac": [ { "id": "NP_013687", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013687", "type": "external" } ], "gene_names_uniprotkb": "YML6", "gene_names_refseq": "YML6; uL4m", "protein_names_uniprotkb": "Large ribosomal subunit protein uL4m; 54S ribosomal protein YmL6, mitochondrial", "protein_names_refseq": "mitochondrial 54S ribosomal protein uL4m YML6", "tax_id": 559292, "disease": "", "pathway": " (sce:YML025C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562095;14562106;14576278;2060626;24374639;24675956;25609543;32597660;33491328;9151978;9169872", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VZE9", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P51998-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P52290-1", "uniprot_id": [ { "id": "PPAD_YEAST", "url": "https://www.uniprot.org/uniprot/P52290", "type": "external" } ], "mass": 53076.0, "length": 468, "protein_name": "Probable acid phosphatase DIA3", "gene_name": "DIA3", "organism": "Yeast", "refseq_name": "putative acid phosphatase DIA3", "refseq_ac": [ { "id": "NP_010260", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010260", "type": "external" } ], "gene_names_uniprotkb": "DIA3; D2815", "gene_names_refseq": "DIA3", "protein_names_uniprotkb": "Probable acid phosphatase DIA3; 3.1.3.2; Digs into agar protein 3", "protein_names_refseq": "putative acid phosphatase DIA3", "tax_id": 559292, "disease": "pontocerebellar hypoplasia type 16 (Disease Ontology:DOID:0112333); papillary thyroid carcinoma (Disease Ontology:DOID:3969)", "pathway": " (sce:YDL024C)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "24374639;9169867", "class_list": "", "function": "", "predicted_glycosites": 11, "predicted_n_glycosites": 11, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 11, "binding_glycan_count": 0, "secondary_ac_list": "D6VRW7", "ec_number_list": [ { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.1.3.54", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.54", "type": "external" }, { "id": "3.1.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.7.6", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" } ], "go_molecular_function": "GO:0003993 acid phosphatase activity", "go_cellular_component": "GO:0071944 cell periphery;GO:0009277 fungal-type cell wall", "go_biological_process": "GO:0001403 invasive growth in response to glucose limitation;GO:0007124 pseudohyphal growth", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P52290-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P52492-1", "uniprot_id": [ { "id": "UBC11_YEAST", "url": "https://www.uniprot.org/uniprot/P52492", "type": "external" } ], "mass": 17753.0, "length": 156, "protein_name": "Ubiquitin-conjugating enzyme E2-18 kDa", "gene_name": "UBC11", "organism": "Yeast", "refseq_name": "putative E2 ubiquitin-protein ligase UBC11", "refseq_ac": [ { "id": "NP_014984", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014984", "type": "external" } ], "gene_names_uniprotkb": "UBC11; O6268", "gene_names_refseq": "UBC11", "protein_names_uniprotkb": "Ubiquitin-conjugating enzyme E2-18 kDa; 2.3.2.23; E2 ubiquitin-conjugating enzyme 11; Ubiquitin carrier protein; Ubiquitin-protein ligase", "protein_names_refseq": "putative E2 ubiquitin-protein ligase UBC11", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR339C); (R-SCE-983168)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "24374639;8948102;9169874;9675819", "class_list": "", "function": "Catalyzes the covalent attachment of ubiquitin to other proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W334", "ec_number_list": [ { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "6.2.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.45", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "1.14.11.27", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.27", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "6.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.2.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004842 ubiquitin-protein transferase activity;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0031145 anaphase-promoting complex-dependent catabolic process;GO:0000209 protein polyubiquitination;GO:0030071 regulation of mitotic metaphase/anaphase transition;GO:0006513 protein monoubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P52492-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P52892-1", "uniprot_id": [ { "id": "ALAT2_YEAST", "url": "https://www.uniprot.org/uniprot/P52892", "type": "external" } ], "mass": 56770.0, "length": 507, "protein_name": "Inactive alanine aminotransferase", "gene_name": "ALT2", "organism": "Yeast", "refseq_name": "alanine transaminase ALT2", "refseq_ac": [ { "id": "NP_010396", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010396", "type": "external" } ], "gene_names_uniprotkb": "ALT2; YD9727.07C", "gene_names_refseq": "ALT2", "protein_names_uniprotkb": "Inactive alanine aminotransferase; GPT; Glutamate pyruvate transaminase; Glutamic--alanine transaminase; Glutamic--pyruvic transaminase", "protein_names_refseq": "alanine transaminase ALT2", "tax_id": 559292, "disease": "neurodevelopmental disorder with spastic paraplegia and microcephaly (Disease Ontology:DOID:0070542); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); obstructive jaundice (Disease Ontology:DOID:13603); acute kidney failure (Disease Ontology:DOID:3021); liver cancer (Disease Ontology:DOID:3571); liver cirrhosis (Disease Ontology:DOID:5082); myocardial infarction (Disease Ontology:DOID:5844); amino acid metabolic disorder (Disease Ontology:DOID:9252); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (sce:YDR111C); (R-SCE-8964540)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "14562095;14562106;17322287;23049841;24374639;29867852;33491328;9169867", "class_list": "", "function": "Inactive alanine aminotransferase. Forms a catalytically active Schiff base with PLP, but lacks alanine transaminase activity, probably due to an altered structural conformation of the dimeric enzyme. This suggests this protein may have a yet undiscovered physiological function., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS97;Q66RF8", "ec_number_list": [], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0008483 transaminase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0042853 L-alanine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P52892-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P52893-1", "uniprot_id": [ { "id": "ALAT1_YEAST", "url": "https://www.uniprot.org/uniprot/P52893", "type": "external" } ], "mass": 66422.0, "length": 592, "protein_name": "Alanine aminotransferase, mitochondrial", "gene_name": "ALT1", "organism": "Yeast", "refseq_name": "alanine transaminase ALT1", "refseq_ac": [ { "id": "NP_013190", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013190", "type": "external" } ], "gene_names_uniprotkb": "ALT1; L9449.15", "gene_names_refseq": "ALT1", "protein_names_uniprotkb": "Alanine aminotransferase, mitochondrial; 2.6.1.2; GPT; Glutamate pyruvate transaminase; Glutamic--alanine transaminase; Glutamic--pyruvic transaminase", "protein_names_refseq": "alanine transaminase ALT1", "tax_id": 559292, "disease": "neurodevelopmental disorder with spastic paraplegia and microcephaly (Disease Ontology:DOID:0070542); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); obstructive jaundice (Disease Ontology:DOID:13603); acute kidney failure (Disease Ontology:DOID:3021); liver cancer (Disease Ontology:DOID:3571); liver cirrhosis (Disease Ontology:DOID:5082); myocardial infarction (Disease Ontology:DOID:5844); amino acid metabolic disorder (Disease Ontology:DOID:9252); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (sce:YLR089C); (R-SCE-70268); (R-SCE-8964540)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "11502169;14562106;19396236;19779198;23049841;24374639;29867852;32597660;33481703;33491328;9169871", "class_list": "", "function": "Alanine aminotransferase involved in both alanine biosynthesis and utilization. Under respiratory conditions, constitutes the sole pathway for alanine biosynthesis and catabolism. Under fermentative conditions, it plays a catabolic role and alanine is mainly synthesized through an alternative pathway., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY89", "ec_number_list": [ { "id": "2.6.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.2", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0042853 L-alanine catabolic process;GO:0006523 alanine biosynthetic process;GO:0006524 alanine catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P52893-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P52911-1", "uniprot_id": [ { "id": "EXG2_YEAST", "url": "https://www.uniprot.org/uniprot/P52911", "type": "external" } ], "mass": 63508.0, "length": 562, "protein_name": "Glucan 1,3-beta-glucosidase 2", "gene_name": "EXG2", "organism": "Yeast", "refseq_name": "glucan exo-1,3-beta-glucosidase", "refseq_ac": [ { "id": "NP_010547", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010547", "type": "external" } ], "gene_names_uniprotkb": "EXG2; YD9320A.12C", "gene_names_refseq": "EXG2", "protein_names_uniprotkb": "Glucan 1,3-beta-glucosidase 2; 3.2.1.58; Exo-1,3-beta-glucanase 2", "protein_names_refseq": "glucan exo-1,3-beta-glucosidase", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR261C)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "14562106;24374639;9169867", "class_list": "glycogene;glycosylhydrolase", "function": "", "predicted_glycosites": 15, "predicted_n_glycosites": 15, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 15, "binding_glycan_count": 0, "secondary_ac_list": "D6VSP1", "ec_number_list": [], "go_molecular_function": "GO:0004338 glucan exo-1,3-beta-glucosidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0009251 glucan catabolic process;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P52911-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.10100", "kg_view_protein": true }, { "uniprot_canonical_ac": "P52923-1", "uniprot_id": [ { "id": "AIF1_YEAST", "url": "https://www.uniprot.org/uniprot/P52923", "type": "external" } ], "mass": 41335.0, "length": 378, "protein_name": "Apoptosis-inducing factor 1", "gene_name": "AIF1", "organism": "Yeast", "refseq_name": "Aif1p", "refseq_ac": [ { "id": "NP_014472", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014472", "type": "external" } ], "gene_names_uniprotkb": "AIF1; CPD1; N3815", "gene_names_refseq": "AIF1; CPD1", "protein_names_uniprotkb": "Apoptosis-inducing factor 1; 1.-.-.-; Cercosporin and photosensitizer-detoxification protein 1", "protein_names_refseq": "Aif1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR074C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "11409174;14562106;15381687;15939758;19684113;24374639;33491328;8904342;9169873", "class_list": "", "function": "Putative FAD-dependent oxidoreductase involved in the resistance to cercosporin and other singlet oxygen-generating photosensitizers. Translocates from mitochondria to the nucleus under apoptotic conditions, where it degrades DNA and induces apoptosis., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1P9", "ec_number_list": [], "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0004174 electron-transferring-flavoprotein dehydrogenase activity;GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0008637 apoptotic mitochondrial changes;GO:0000304 response to singlet oxygen;GO:0110076 negative regulation of ferroptosis", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P52923-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P52924-1", "uniprot_id": [ { "id": "COS10_YEAST", "url": "https://www.uniprot.org/uniprot/P52924", "type": "external" } ], "mass": 43867.0, "length": 374, "protein_name": "Protein COS10", "gene_name": "COS10", "organism": "Yeast", "refseq_name": "Cos10p", "refseq_ac": [ { "id": "NP_014473", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014473", "type": "external" } ], "gene_names_uniprotkb": "COS10; N3820", "gene_names_refseq": "COS10", "protein_names_uniprotkb": "Protein COS10", "protein_names_refseq": "Cos10p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR075W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;16847258;24374639;8904342;9169873", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1Q0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0006897 endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P52924-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53032-1", "uniprot_id": [ { "id": "SUT1_YEAST", "url": "https://www.uniprot.org/uniprot/P53032", "type": "external" } ], "mass": 33191.0, "length": 299, "protein_name": "Sterol uptake protein 1", "gene_name": "SUT1", "organism": "Yeast", "refseq_name": "Sut1p", "refseq_ac": [ { "id": "NP_011353", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011353", "type": "external" } ], "gene_names_uniprotkb": "SUT1; G1828", "gene_names_refseq": "SUT1", "protein_names_uniprotkb": "Sterol uptake protein 1", "protein_names_refseq": "Sut1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL162W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "11248676;11401714;12435498;14562095;14562106;15035656;19779198;23223039;23749301;23872066;24374639;33481703;33491328;7489925;8585324;9169869", "class_list": "", "function": "Transcription factor involved in the induction of hypoxic gene transcription when the cells are shifted from aerobiosis to anaerobiosis (PubMed:11248676, PubMed:11401714, PubMed:15035656). Promotes exogenous sterol uptake and stimulates endogenous sterol biosynthesis (PubMed:11248676, PubMed:11401714, PubMed:12435498, PubMed:7489925). With SUT2, positively regulates mating by repressing the expression of the mating inhibitors NCE102, PRR2 and RHO5 in response to pheromone (PubMed:23872066). Finally, regulates filamentation via the repression of genes such as GAT2, HAP4, MGA1, MSN4, NCE102, PRR2, RHO3, and RHO5, when nutrients are plentifu (PubMed:23223039)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTY9", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0009267 cellular response to starvation;GO:1900237 positive regulation of induction of conjugation with cellular fusion", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P53032-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53036-1", "uniprot_id": [ { "id": "SAP4_YEAST", "url": "https://www.uniprot.org/uniprot/P53036", "type": "external" } ], "mass": 94729.0, "length": 818, "protein_name": "SIT4-associating protein SAP4", "gene_name": "SAP4", "organism": "Yeast", "refseq_name": "Sap4p", "refseq_ac": [ { "id": "NP_011285", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011285", "type": "external" } ], "gene_names_uniprotkb": "SAP4", "gene_names_refseq": "SAP4", "protein_names_uniprotkb": "SIT4-associating protein SAP4", "protein_names_refseq": "Sap4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL229C); (R-SCE-204005)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "14562106;19779198;24374639;32597660;33491328;8649382;9169869", "class_list": "", "function": "Associates with the SIT4 phosphatase in a cell cycle dependent manner. May be directly or indirectly involved in SIT4-dependent functions in budding and in normal G1 cyclin expression (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVA5", "ec_number_list": [], "go_molecular_function": "GO:0019888 protein phosphatase regulator activity;GO:0019903 protein phosphatase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0000082 G1/S transition of mitotic cell cycle;GO:0009966 regulation of signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P53036-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53046-1", "uniprot_id": [ { "id": "ROM1_YEAST", "url": "https://www.uniprot.org/uniprot/P53046", "type": "external" } ], "mass": 131420.0, "length": 1155, "protein_name": "RHO1 GDP-GTP exchange protein 1", "gene_name": "ROM1", "organism": "Yeast", "refseq_name": "Rho family guanine nucleotide exchange factor ROM1", "refseq_ac": [ { "id": "NP_011584", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011584", "type": "external" } ], "gene_names_uniprotkb": "ROM1; SKC1", "gene_names_refseq": "ROM1; SKC1", "protein_names_uniprotkb": "RHO1 GDP-GTP exchange protein 1; Protein kinase C suppressor SKC1", "protein_names_refseq": "Rho family guanine nucleotide exchange factor ROM1", "tax_id": 559292, "disease": "Charcot-Marie-Tooth disease type 4H (Disease Ontology:DOID:0110192); Charcot-Marie-Tooth disease (Disease Ontology:DOID:10595); X-linked Aarskog syndrome (Disease Ontology:DOID:6683)", "pathway": " (sce:YGR070W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "18407956;19779198;20489023;21126336;22814378;23749301;24374639;32597660;33481703;33491328;8641285;9169869", "class_list": "", "function": "Stimulates the exchange of RHO1 GDP-bound form into GTP-bound form., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q92326", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0071944 cell periphery;GO:0032153 cell division site", "go_biological_process": "GO:0007264 small GTPase-mediated signal transduction;GO:1903338 regulation of cell wall organization or biogenesis", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P53046-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53047-1", "uniprot_id": [ { "id": "RTA1_YEAST", "url": "https://www.uniprot.org/uniprot/P53047", "type": "external" } ], "mass": 35486.0, "length": 317, "protein_name": "Protein RTA1", "gene_name": "RTA1", "organism": "Yeast", "refseq_name": "Rta1p", "refseq_ac": [ { "id": "NP_011729", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011729", "type": "external" } ], "gene_names_uniprotkb": "RTA1", "gene_names_refseq": "RTA1", "protein_names_uniprotkb": "Protein RTA1", "protein_names_refseq": "Rta1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR213C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "16847258;17322287;24374639;8660468;9169869;9290212", "class_list": "", "function": "Involved in 7-aminocholesterol resistance., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, 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"0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53050-1", "uniprot_id": [ { "id": "MGA1_YEAST", "url": "https://www.uniprot.org/uniprot/P53050", "type": "external" } ], "mass": 50735.0, "length": 456, "protein_name": "Protein MGA1", "gene_name": "MGA1", "organism": "Yeast", "refseq_name": "Mga1p", "refseq_ac": [ { "id": "NP_011765", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011765", "type": "external" } ], "gene_names_uniprotkb": "MGA1", "gene_names_refseq": "MGA1", "protein_names_uniprotkb": "Protein MGA1", "protein_names_refseq": "Mga1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR249W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "24374639;33491328;9133742;9169869", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VV29", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0007124 pseudohyphal growth", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P53050-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53058-1", "uniprot_id": [ { "id": "VEL1_YEAST", "url": "https://www.uniprot.org/uniprot/P53058", "type": "external" } ], "mass": 22152.0, "length": 206, "protein_name": "Protein VEL1", "gene_name": "VEL1", "organism": "Yeast", "refseq_name": "Vel1p", "refseq_ac": [ { "id": "NP_011256", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011256", "type": "external" } ], "gene_names_uniprotkb": "VEL1; NRA206", "gene_names_refseq": "VEL1", "protein_names_uniprotkb": "Protein VEL1; Velum formation protein 1", "protein_names_refseq": "Vel1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL258W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11935221;12788058;14660410;19756047;24374639;8972578;9169869", "class_list": "", "function": "", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VV77", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0071944 cell periphery", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P53058-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53059-1", "uniprot_id": [ { "id": "MNT2_YEAST", "url": "https://www.uniprot.org/uniprot/P53059", "type": "external" } ], "mass": 64853.0, "length": 558, "protein_name": "Alpha-1,3-mannosyltransferase MNT2", "gene_name": "MNT2", "organism": "Yeast", "refseq_name": "alpha-1,3-mannosyltransferase MNT2", "refseq_ac": [ { "id": "NP_011257", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011257", "type": "external" } ], "gene_names_uniprotkb": "MNT2; NRD558", "gene_names_refseq": "MNT2", "protein_names_uniprotkb": "Alpha-1,3-mannosyltransferase MNT2; 2.4.1.-", "protein_names_refseq": "alpha-1,3-mannosyltransferase MNT2", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL257C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10521541;14562106;24374639;8972578;9169869", "class_list": "glycogene;glycosyltransferase", "function": "Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VV78", "ec_number_list": [], "go_molecular_function": "GO:0000033 alpha-1,3-mannosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0071944 cell periphery;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0006493 protein O-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P53059-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53060-1", "uniprot_id": [ { "id": "RMR1_YEAST", "url": "https://www.uniprot.org/uniprot/P53060", "type": "external" } ], "mass": 27709.0, "length": 241, "protein_name": "Reduced meiotic recombination protein 1", "gene_name": "RMR1", "organism": "Yeast", "refseq_name": "Rmr1p", "refseq_ac": [ { "id": "NP_011264", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011264", "type": "external" } ], "gene_names_uniprotkb": "RMR1; NRC245", "gene_names_refseq": "RMR1", "protein_names_uniprotkb": "Reduced meiotic recombination protein 1", "protein_names_refseq": "Rmr1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL250W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12748633;14562095;14562106;15590687;18069899;24374639;33491328;8972578;9169869", "class_list": "", "function": "Required for normal levels of gene conversion events during meiosis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV85", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0007131 reciprocal meiotic recombination;GO:0006311 meiotic gene conversion", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P53060-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53062-1", "uniprot_id": [ { "id": "BRR6_YEAST", "url": "https://www.uniprot.org/uniprot/P53062", "type": "external" } ], "mass": 22807.0, "length": 197, "protein_name": "Nucleus export protein BRR6", "gene_name": "BRR6", "organism": "Yeast", "refseq_name": "Brr6p", "refseq_ac": [ { "id": "NP_011267", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011267", "type": "external" } ], "gene_names_uniprotkb": "BRR6; NRA197", "gene_names_refseq": "BRR6", "protein_names_uniprotkb": "Nucleus export protein BRR6; Bad response to refrigeration protein 6", "protein_names_refseq": "Brr6p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL247W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11483521;14562095;14562106;15882446;17322287;24374639;8972578;9169869", "class_list": "", "function": "Required for mRNA nuclear export. Involved in the nuclear pore complex (NPC) distribution and nuclear envelope morphology., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV88", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005783 endoplasmic reticulum;GO:0031965 nuclear membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0055088 lipid homeostasis;GO:0006998 nuclear envelope organization;GO:0051028 mRNA transport", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P53062-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53065-1", "uniprot_id": [ { "id": "TAD1_YEAST", "url": "https://www.uniprot.org/uniprot/P53065", "type": "external" } ], "mass": 45947.0, "length": 400, "protein_name": "tRNA-specific adenosine deaminase 1", "gene_name": "TAD1", "organism": "Yeast", "refseq_name": "tRNA-specific adenosine deaminase", "refseq_ac": [ { "id": "NP_011271", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011271", "type": "external" } ], "gene_names_uniprotkb": "TAD1; HRA400", "gene_names_refseq": "TAD1", "protein_names_uniprotkb": "tRNA-specific adenosine deaminase 1; 3.5.4.34; tRNA-specific adenosine-37 deaminase", "protein_names_refseq": "tRNA-specific adenosine deaminase", "tax_id": 559292, "disease": "transient cerebral ischemia (Disease Ontology:DOID:224); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YGL243W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "16141067;24374639;33491328;8750240;9169869;9707437", "class_list": "", "function": "Deaminates adenosine-37 to inosine in tRNA-Ala., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV92", "ec_number_list": [ { "id": "3.5.4.34", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.34", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0008251 tRNA-specific adenosine deaminase activity;GO:0046872 metal ion binding;GO:0043829 tRNA-specific adenosine-37 deaminase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0002100 tRNA wobble adenosine to inosine editing;GO:0006400 tRNA modification", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P53065-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53070-1", "uniprot_id": [ { "id": "MTO1_YEAST", "url": "https://www.uniprot.org/uniprot/P53070", "type": "external" } ], "mass": 74215.0, "length": 669, "protein_name": "Mitochondrial translation optimization protein 1", "gene_name": "MTO1", "organism": "Yeast", "refseq_name": "tRNA modification protein MTO1", "refseq_ac": [ { "id": "NP_011278", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011278", "type": "external" } ], "gene_names_uniprotkb": "MTO1; IPS1", "gene_names_refseq": "IPS1; MTO1", "protein_names_uniprotkb": "Mitochondrial translation optimization protein 1", "protein_names_refseq": "tRNA modification protein MTO1", "tax_id": 559292, "disease": "nonsyndromic deafness (Disease Ontology:DOID:0050563); combined oxidative phosphorylation deficiency (Disease Ontology:DOID:0060286); combined oxidative phosphorylation deficiency 10 (Disease Ontology:DOID:0111480)", "pathway": " (sce:YGL236C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12748633;22608499;24374639;33491328;9169869;9774408", "class_list": "", "function": "Component of the MSS1-MTO1 complex that catalyzes the 5-carboxymethylaminomethyluridine (cmnm(5)U) modification at the 34th wobble position (U34) of mitochondrial tRNAs., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV98", "ec_number_list": [], "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0030488 tRNA methylation;GO:0070899 mitochondrial tRNA wobble uridine modification", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P53070-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53072-1", "uniprot_id": [ { "id": "TAN1_YEAST", "url": "https://www.uniprot.org/uniprot/P53072", "type": "external" } ], "mass": 33550.0, "length": 289, "protein_name": "tRNA acetyltransferase TAN1", "gene_name": "TAN1", "organism": "Yeast", "refseq_name": "putative tRNA acetyltransferase", "refseq_ac": [ { "id": "NP_011282", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011282", "type": "external" } ], "gene_names_uniprotkb": "TAN1", "gene_names_refseq": "TAN1", "protein_names_uniprotkb": "tRNA acetyltransferase TAN1; 2.3.-.-", "protein_names_refseq": "putative tRNA acetyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL232W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "14562095;14562106;15037780;17330950;17563356;18407956;19779198;19795423;19823750;24374639;32597660;33481703;33491328;9169869", "class_list": "", "function": "Probable tRNA acetyltransferase required for the formation of the modified nucleoside N(4)-acetylcytidine in serine and leucine tRNAs. Binds RNA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVA2", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0016746 acyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0051391 tRNA acetylation;GO:0006400 tRNA modification", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P53072-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53073-1", "uniprot_id": [ { "id": "EMC4_YEAST", "url": "https://www.uniprot.org/uniprot/P53073", "type": "external" } ], "mass": 21460.0, "length": 190, "protein_name": "ER membrane protein complex subunit 4", "gene_name": "EMC4", "organism": "Yeast", "refseq_name": "chaperone EMC4", "refseq_ac": [ { "id": "NP_011283", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011283", "type": "external" } ], "gene_names_uniprotkb": "EMC4", "gene_names_refseq": "EMC4", "protein_names_uniprotkb": "ER membrane protein complex subunit 4", "protein_names_refseq": "chaperone EMC4", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL231C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562095;14562106;15665377;17322287;19325107;21126336;23749301;24374639;29809151;32597660;33481703;9169869", "class_list": "", "function": "Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins (PubMed:29809151). Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues (PubMed:29809151). Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices (PubMed:29809151). It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVA3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0072546 EMC complex;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0015914 phospholipid transport;GO:0006644 phospholipid metabolic process;GO:0034975 protein folding in endoplasmic reticulum;GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P53073-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53075-1", "uniprot_id": [ { "id": "SHE10_YEAST", "url": "https://www.uniprot.org/uniprot/P53075", "type": "external" } ], "mass": 66862.0, "length": 577, "protein_name": "Outer spore wall assembly protein SHE10", "gene_name": "SHE10", "organism": "Yeast", "refseq_name": "She10p", "refseq_ac": [ { "id": "NP_011286", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011286", "type": "external" } ], "gene_names_uniprotkb": "SHE10", "gene_names_refseq": "SHE10", "protein_names_uniprotkb": "Outer spore wall assembly protein SHE10; Sensitivity to high expression protein 10", "protein_names_refseq": "She10p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL228W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;20086051;23966878;24374639;33481703;7762298;9169869", "class_list": "", "function": "Involved in spore wall assembly (PubMed:23966878). May be a component of the mitochondrial RNase MRP (MtMRP), a ribonucleoprotein endoribonuclease involved in the cleaving RNA transcripts to generate primers for DNA replication in mitochondria (PubMed:20086051). Causes growth arrest when highly overexpressed (PubMed:7762298)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVA6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0030476 ascospore wall assembly", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P53075-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53080-1", "uniprot_id": [ { "id": "EDC1_YEAST", "url": "https://www.uniprot.org/uniprot/P53080", "type": "external" } ], "mass": 19238.0, "length": 175, "protein_name": "Enhancer of mRNA-decapping protein 1", "gene_name": "EDC1", "organism": "Yeast", "refseq_name": "Edc1p", "refseq_ac": [ { "id": "NP_011293", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011293", "type": "external" } ], "gene_names_uniprotkb": "EDC1", "gene_names_refseq": "EDC1", "protein_names_uniprotkb": "Enhancer of mRNA-decapping protein 1", "protein_names_refseq": "Edc1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL222C)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "11139489;12554866;12554867;14562095;17287358;17322287;17563356;18407956;19779198;19795423;19823750;20702584;21177495;22814378;23749301;24374639;27821475;32597660;33481703;33491328;9169869;9290212", "class_list": "", "function": "mRNA-binding protein which stimulates mRNA decapping by DCP1 and DCP2. Involved in the regulation of expression of multiple genes involved in glycolysis and gluconeogenesis., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVB3", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0098745 RNA decapping complex", "go_biological_process": "GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0006397 mRNA processing;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0032056 positive regulation of translation in response to stress", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P53080-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53094-1", "uniprot_id": [ { "id": "MDS3_YEAST", "url": "https://www.uniprot.org/uniprot/P53094", "type": "external" } ], "mass": 166971.0, "length": 1487, "protein_name": "Negative regulator of sporulation MDS3", "gene_name": "MDS3", "organism": "Yeast", "refseq_name": "Mds3p", "refseq_ac": [ { "id": "NP_011318", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011318", "type": "external" } ], "gene_names_uniprotkb": "MDS3; G1307", "gene_names_refseq": "MDS3", "protein_names_uniprotkb": "Negative regulator of sporulation MDS3; MCK1 dosage suppressor 3", "protein_names_refseq": "Mds3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL197W); (R-SCE-6798695)", "pathway_count": 2, "publication_count": 26, "publication_id_list": "12524333;14562095;14562106;15665377;17330950;17563356;18407956;19087957;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;23749301;24374639;30516470;32597660;33229814;33481703;33491328;9046087;9169869;9383076", "class_list": "", "function": "Negatively regulates early sporulation-specific genes. Seems to exert its function by positively regulating the Ras/cAMP pathway. Required for growth under alkaline conditions. Acts synergetically with PMD1., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 18, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 18, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 18, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 118, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 17, "binding_glycan_count": 0, "secondary_ac_list": "D6VTV6", "ec_number_list": [], "go_molecular_function": "GO:0004601 peroxidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0031929 TOR signaling;GO:0045454 cell redox homeostasis;GO:0051321 meiotic cell cycle;GO:0007124 pseudohyphal growth;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 4.6, "record_id": "P53094-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53099-1", "uniprot_id": [ { "id": "TPN1_YEAST", "url": "https://www.uniprot.org/uniprot/P53099", "type": "external" } ], "mass": 64546.0, "length": 579, "protein_name": "Vitamin B6 transporter TPN1", "gene_name": "TPN1", "organism": "Yeast", "refseq_name": "Tpn1p", "refseq_ac": [ { "id": "NP_011329", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011329", "type": "external" } ], "gene_names_uniprotkb": "TPN1; G1370", "gene_names_refseq": "TPN1", "protein_names_uniprotkb": "Vitamin B6 transporter TPN1; Transport of pyridoxine protein 1", "protein_names_refseq": "Tpn1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL186C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12649274;16847258;24374639;9046087;9169869", "class_list": "", "function": "Thiamine-regulated, high affinity import carrier of pyridoxine, pyridoxal and pyridoxamine., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTW8", "ec_number_list": [], "go_molecular_function": "GO:0090482 vitamin transmembrane transporter activity;GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0051180 vitamin transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P53099-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53100-1", "uniprot_id": [ { "id": "YGT5_YEAST", "url": "https://www.uniprot.org/uniprot/P53100", "type": "external" } ], "mass": 42984.0, "length": 379, "protein_name": "Putative 2-hydroxyacid dehydrogenase YGL185C", "gene_name": "G1380", "organism": "Yeast", "refseq_name": "putative hydroxyacid dehydrogenase", "refseq_ac": [ { "id": "NP_011330", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011330", "type": "external" } ], "gene_names_uniprotkb": "G1380", "gene_names_refseq": "", "protein_names_uniprotkb": "Putative 2-hydroxyacid dehydrogenase YGL185C; 1.-.-.-", "protein_names_refseq": "putative hydroxyacid dehydrogenase", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL185C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;23749301;24374639;33491328;9046087;9169869", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTW9", "ec_number_list": [], "go_molecular_function": "GO:0016618 hydroxypyruvate reductase [NAD(P)H] activity;GO:0030267 glyoxylate reductase (NADPH) activity;GO:0051287 NAD binding;GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0004617 phosphoglycerate dehydrogenase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P53100-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53102-1", "uniprot_id": [ { "id": "MND1_YEAST", "url": "https://www.uniprot.org/uniprot/P53102", "type": "external" } ], "mass": 26083.0, "length": 219, "protein_name": "Meiotic nuclear division protein 1", "gene_name": "MND1", "organism": "Yeast", "refseq_name": "Mnd1p", "refseq_ac": [ { "id": "NP_011332", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011332", "type": "external" } ], "gene_names_uniprotkb": "MND1; G1604", "gene_names_refseq": "MND1", "protein_names_uniprotkb": "Meiotic nuclear division protein 1", "protein_names_refseq": "Mnd1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL183C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "11940665;12011448;15120066;15249670;17322287;24374639;33481703;9046087;9169869", "class_list": "", "function": "Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Stimulates DMC1-dependent homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTX1", "ec_number_list": [], "go_molecular_function": "GO:0003690 double-stranded DNA binding;GO:0120230 recombinase activator activity", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005634 nucleus;GO:0120231 DNA recombinase auxiliary factor complex", "go_biological_process": "GO:0007129 homologous chromosome pairing at meiosis;GO:0007131 reciprocal meiotic recombination;GO:0000709 meiotic joint molecule formation;GO:0010774 meiotic strand invasion involved in reciprocal meiotic recombination", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P53102-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53107-1", "uniprot_id": [ { "id": "YRB30_YEAST", "url": "https://www.uniprot.org/uniprot/P53107", "type": "external" } ], "mass": 50296.0, "length": 440, "protein_name": "Ran-specific GTPase-activating protein 30", "gene_name": "YRB30", "organism": "Yeast", "refseq_name": "Yrb30p", "refseq_ac": [ { "id": "NP_011351", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011351", "type": "external" } ], "gene_names_uniprotkb": "YRB30; G1817", "gene_names_refseq": "YRB30", "protein_names_uniprotkb": "Ran-specific GTPase-activating protein 30; RANBP30; Ran-binding protein 30", "protein_names_refseq": "Yrb30p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL164C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12578832;14562106;19779198;24374639;3052856;33491328;8585324;9169869", "class_list": "", "function": "Important for the export of protein containing nuclear export signal (NES) out of the nucleus. Stimulates the GTPase activity of GSP1., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTY7;Q6LDS2", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0030695 GTPase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P53107-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53111-1", "uniprot_id": [ { "id": "ARI1_YEAST", "url": "https://www.uniprot.org/uniprot/P53111", "type": "external" } ], "mass": 38083.0, "length": 347, "protein_name": "NADPH-dependent aldehyde reductase ARI1", "gene_name": "ARI1", "organism": "Yeast", "refseq_name": "carbonyl reductase (NADPH-dependent) ARI1", "refseq_ac": [ { "id": "NP_011358", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011358", "type": "external" } ], "gene_names_uniprotkb": "ARI1; G1857", "gene_names_refseq": "ARI1", "protein_names_uniprotkb": "NADPH-dependent aldehyde reductase ARI1; 1.1.1.-", "protein_names_refseq": "carbonyl reductase (NADPH-dependent) ARI1", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL157W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;14562106;14574691;19577617;20525870;24374639;33481703;33491328;8585324;9169869", "class_list": "", "function": "NADPH-dependent aldehyde reductase involved in the detoxification of aldehyde inhibitors derived from lignocellulosic biomass conversion. Reduces commonly detected inhibitors in biomass conversion hydrolysates such as furfural, 5-hydroxymethylfurfural (HMF), cinnamic aldehyde, benzaldehyde, phenylacetaldehyde, and anisaldehyde., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTZ4", "ec_number_list": [], "go_molecular_function": "GO:0016491 oxidoreductase activity;GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0004090 carbonyl reductase (NADPH) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P53111-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53123-1", "uniprot_id": [ { "id": "MRM2_YEAST", "url": "https://www.uniprot.org/uniprot/P53123", "type": "external" } ], "mass": 37423.0, "length": 320, "protein_name": "rRNA methyltransferase 2, mitochondrial", "gene_name": "MRM2", "organism": "Yeast", "refseq_name": "21S rRNA (uridine2791-2'-O) methyltransferase", "refseq_ac": [ { "id": "NP_011379", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011379", "type": "external" } ], "gene_names_uniprotkb": "MRM2; G2830", "gene_names_refseq": "MRM2", "protein_names_uniprotkb": "rRNA methyltransferase 2, mitochondrial; 2.1.1.168; 21S rRNA (uridine(2791)-2'-O)-methyltransferase; 21S rRNA [Um2791] 2'-O-methyltransferase", "protein_names_refseq": "21S rRNA (uridine2791-2'-O) methyltransferase", "tax_id": 559292, "disease": "mitochondrial DNA depletion syndrome 17 (Disease Ontology:DOID:0070448); MELAS syndrome (Disease Ontology:DOID:3687)", "pathway": " (sce:YGL136C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11867542;17322287;24374639;8840506;9169869", "class_list": "", "function": "S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 2791 (Um2791) in the 21S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VU13", "ec_number_list": [ { "id": "2.1.1.168", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.168", "type": "external" } ], "go_molecular_function": "GO:0008650 rRNA (uridine-2'-O-)-methyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0031167 rRNA methylation;GO:0001510 RNA methylation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P53123-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53128-1", "uniprot_id": [ { "id": "MTHR2_YEAST", "url": "https://www.uniprot.org/uniprot/P53128", "type": "external" } ], "mass": 68560.0, "length": 600, "protein_name": "Methylenetetrahydrofolate reductase 2", "gene_name": "MET13", "organism": "Yeast", "refseq_name": "methylenetetrahydrofolate reductase (NAD(P)H) MET13", "refseq_ac": [ { "id": "NP_011390", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011390", "type": "external" } ], "gene_names_uniprotkb": "MET13; G2882; MET11; MRPL45", "gene_names_refseq": "MET11; MET13; MRPL45", "protein_names_uniprotkb": "Methylenetetrahydrofolate reductase 2; 1.5.1.53; YmL45", "protein_names_refseq": "methylenetetrahydrofolate reductase (NAD(P)H) MET13", "tax_id": 559292, "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589); diffuse large B-cell lymphoma (Disease Ontology:DOID:0050745); peripheral artery disease (Disease Ontology:DOID:0050830); non-arteritic anterior ischemic optic neuropathy (Disease Ontology:DOID:0050864); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); coarctation of the aorta (Disease Ontology:DOID:0051054); stroke (Disease Ontology:DOID:0051061); dextro-looped transposition of the great arteries (Disease Ontology:DOID:0060770); myeloid neoplasm (Disease Ontology:DOID:0070004); spina bifida (Disease Ontology:DOID:0080016); neural tube defect (Disease Ontology:DOID:0080074); hepatic veno-occlusive disease (Disease Ontology:DOID:0080177); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); graft-versus-host disease (Disease Ontology:DOID:0081267); thrombophilia due to thrombin defect (Disease Ontology:DOID:0111907); migraine with aura (Disease Ontology:DOID:10024); open-angle glaucoma (Disease Ontology:DOID:1067); kidney failure (Disease Ontology:DOID:1074); Kuhnt-Junius degeneration (Disease Ontology:DOID:10873); sickle cell anemia (Disease Ontology:DOID:10923); attention 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(Disease Ontology:DOID:1984); hepatitis B (Disease Ontology:DOID:2043); nephroblastoma (Disease Ontology:DOID:2154); anemia (Disease Ontology:DOID:2355); renal artery disease (Disease Ontology:DOID:2388); thrombophilia (Disease Ontology:DOID:2452); transitional cell carcinoma (Disease Ontology:DOID:2671); asthma (Disease Ontology:DOID:2841); glomerulonephritis (Disease Ontology:DOID:2921); familial Mediterranean fever (Disease Ontology:DOID:2987); lipid metabolism disorder (Disease Ontology:DOID:3146); ischemia (Disease Ontology:DOID:326); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); osteosarcoma (Disease Ontology:DOID:3347); coronary artery disease (Disease Ontology:DOID:3393); cerebral infarction (Disease Ontology:DOID:3526); cervical cancer (Disease Ontology:DOID:4362); renal cell carcinoma (Disease Ontology:DOID:4450); clear cell renal cell carcinoma (Disease Ontology:DOID:4467); cholangiocarcinoma (Disease Ontology:DOID:4947); liver cirrhosis (Disease Ontology:DOID:5082); lung small cell carcinoma (Disease Ontology:DOID:5409); schizophrenia (Disease Ontology:DOID:5419); eye disease (Disease Ontology:DOID:5614); myocardial infarction (Disease Ontology:DOID:5844); mitral valve disease (Disease Ontology:DOID:61); migraine (Disease Ontology:DOID:6364); tetralogy of Fallot (Disease Ontology:DOID:6419); hepatocellular carcinoma (Disease Ontology:DOID:684); ankylosing spondylitis (Disease Ontology:DOID:7147); rheumatoid arthritis (Disease Ontology:DOID:7148); abdominal aortic aneurysm (Disease Ontology:DOID:7693); end stage renal disease (Disease Ontology:DOID:783); chronic kidney disease (Disease Ontology:DOID:784); hyperthyroidism (Disease Ontology:DOID:7998); cataract (Disease Ontology:DOID:83); chronic myeloid leukemia (Disease Ontology:DOID:8552); smallpox (Disease Ontology:DOID:8736); diabetic retinopathy (Disease Ontology:DOID:8947); acute myeloid leukemia (Disease Ontology:DOID:9119); liver benign neoplasm (Disease 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{ "id": "1.5.1.53", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.53", "type": "external" } ], "go_molecular_function": "GO:0071949 FAD binding;GO:0004489 methylenetetrahydrofolate reductase [NAD(P)H] activity;GO:0106313 methylenetetrahydrofolate reductase (NADPH) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0035999 tetrahydrofolate interconversion;GO:0009086 methionine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P53128-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53139-1", "uniprot_id": [ { "id": "YGK8_YEAST", "url": "https://www.uniprot.org/uniprot/P53139", "type": "external" } ], "mass": 16037.0, "length": 140, "protein_name": "Uncharacterized protein YGL108C", "gene_name": "G3070", "organism": "Yeast", "refseq_name": "uncharacterized protein", 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"uniprot_canonical_ac": "P53142-1", "uniprot_id": [ { "id": "VPS73_YEAST", "url": "https://www.uniprot.org/uniprot/P53142", "type": "external" } ], "mass": 54331.0, "length": 486, "protein_name": "Vacuolar protein sorting-associated protein 73", "gene_name": "VPS73", "organism": "Yeast", "refseq_name": "putative sugar transporter", "refseq_ac": [ { "id": "NP_011411", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011411", "type": "external" } ], "gene_names_uniprotkb": "VPS73; G3090", "gene_names_refseq": "VPS73", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 73", "protein_names_refseq": "putative sugar transporter", "tax_id": 559292, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); myelomeningocele (Disease Ontology:DOID:0060326); abdominal obesity-metabolic syndrome (Disease Ontology:DOID:0060611); glucose transporter type 1 deficiency syndrome (Disease Ontology:DOID:0070560); glucose transporter type 1 deficiency syndrome 1 (Disease Ontology:DOID:0070561); Fanconi-Bickel syndrome (Disease Ontology:DOID:0070562); dystonia 9 (Disease Ontology:DOID:0090044); glucose transporter type 1 deficiency syndrome 2 (Disease Ontology:DOID:0090045); Hirschsprung's disease (Disease Ontology:DOID:10487); pre-eclampsia (Disease Ontology:DOID:10591); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); hypothyroidism (Disease Ontology:DOID:1459); childhood absence epilepsy (Disease Ontology:DOID:1825); hyperuricemia (Disease Ontology:DOID:1920); nephroblastoma (Disease Ontology:DOID:2154); hemangioma (Disease Ontology:DOID:255); glycogen storage disease (Disease Ontology:DOID:2747); acanthosis nigricans (Disease Ontology:DOID:3138); coronary artery disease (Disease Ontology:DOID:3393); middle cerebral artery infarction (Disease Ontology:DOID:3525); insulinoma (Disease Ontology:DOID:3892); gastrinoma (Disease Ontology:DOID:5577); congestive heart failure (Disease Ontology:DOID:6000); pulmonary hypertension (Disease Ontology:DOID:6432); cataract (Disease Ontology:DOID:83); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YGL104C); (R-SCE-189200); (R-SCE-196836); (R-SCE-422356); (R-SCE-6798695); (R-SCE-8981373)", "pathway_count": 6, "publication_count": 13, "publication_id_list": "12134085;14576278;16847258;18407956;19779198;21126336;23749301;24374639;33481703;33491328;9046090;9169869;9290212", "class_list": "", "function": "May be involved in vacuolar protein sorting., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, 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218, "protein_name": "Biogenesis of lysosome-related organelles complex 1 subunit KXD1", "gene_name": "KXD1", "organism": "Yeast", "refseq_name": "Kxd1p", "refseq_ac": [ { "id": "NP_011436", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011436", "type": "external" } ], "gene_names_uniprotkb": "KXD1", "gene_names_refseq": "KXD1", "protein_names_uniprotkb": "Biogenesis of lysosome-related organelles complex 1 subunit KXD1; BLOC-1 subunit KXD1; KxDL homolog", "protein_names_refseq": "Kxd1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL079W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;17322287;21159114;24374639;33491328;9169869;9290212", "class_list": "", "function": "Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, 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"ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005768 endosome;GO:0031083 BLOC-1 complex", "go_biological_process": "GO:0032880 regulation of protein localization;GO:0007032 endosome organization", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P53158-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53167-1", "uniprot_id": [ { "id": "PUS2_YEAST", "url": "https://www.uniprot.org/uniprot/P53167", "type": "external" } ], "mass": 41891.0, "length": 370, "protein_name": "tRNA pseudouridine(27/28) synthase", "gene_name": "PUS2", "organism": "Yeast", "refseq_name": "pseudouridine synthase PUS2", "refseq_ac": [ { "id": "NP_011452", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011452", "type": "external" } ], "gene_names_uniprotkb": "PUS2", "gene_names_refseq": "PUS2", "protein_names_uniprotkb": "tRNA pseudouridine(27/28) synthase; 5.4.99.44; tRNA pseudouridine synthase 2; tRNA pseudouridylate synthase 2; tRNA-uridine isomerase 2", "protein_names_refseq": "pseudouridine synthase PUS2", "tax_id": 559292, "disease": "myopathy, lactic acidosis, and sideroblastic anemia (Disease Ontology:DOID:0080099); myopathy, lactic acidosis, and sideroblastic anemia 1 (Disease Ontology:DOID:0111185)", "pathway": " (sce:YGL063W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "17684231;24374639;8641292;9169869;9234674", "class_list": "", "function": "Mitochondrial-specific pseudouridine synthase catalyzing the formation of pseudouridine at positions 27 and 28 in the anticodon stem and loop of mitochondrial transfer RNAs., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, 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"go_molecular_function": "GO:0003723 RNA binding;GO:0009982 pseudouridine synthase activity;GO:0160153 mitochondrial tRNA pseudouridine(27/28) synthase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0031119 tRNA pseudouridine synthesis;GO:1990481 mRNA pseudouridine synthesis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P53167-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53172-1", "uniprot_id": [ { "id": "SDS23_YEAST", "url": "https://www.uniprot.org/uniprot/P53172", "type": "external" } ], "mass": 58098.0, "length": 527, "protein_name": "Protein SDS23", "gene_name": "SDS23", "organism": "Yeast", "refseq_name": "Sds23p", "refseq_ac": [ { "id": "NP_011459", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011459", "type": "external" } ], "gene_names_uniprotkb": "SDS23", "gene_names_refseq": "SDS23", "protein_names_uniprotkb": "Protein SDS23", "protein_names_refseq": "Sds23p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL056C)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "14562095;14562106;15665377;16041152;17287358;17322287;17330950;17563356;18407956;19779198;19795423;20702584;21126336;23749301;24374639;32597660;33481703;33491328;9169869;9234674", "class_list": "", "function": "Involved in DNA replication and cell separation during budding., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 25, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VU85;Q6B1R7", "ec_number_list": [], "go_molecular_function": "GO:0004865 protein serine/threonine phosphatase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000920 septum digestion after cytokinesis;GO:0042149 cellular response to glucose starvation;GO:0030071 regulation of mitotic metaphase/anaphase transition", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P53172-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53174-1", "uniprot_id": [ { "id": "PRM8_YEAST", "url": "https://www.uniprot.org/uniprot/P53174", "type": "external" } ], "mass": 27250.0, "length": 237, "protein_name": "Pheromone-regulated membrane protein 8", "gene_name": "PRM8", "organism": "Yeast", "refseq_name": "pheromone-regulated DUP240 family protein PRM8", "refseq_ac": [ { "id": "NP_011462", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011462", "type": "external" } ], "gene_names_uniprotkb": "PRM8; DUP1", "gene_names_refseq": "PRM8", "protein_names_uniprotkb": "Pheromone-regulated membrane protein 8; DUP240 protein PRM8; Protein DUP1", "protein_names_refseq": "pheromone-regulated DUP240 family protein PRM8", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL053W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "11062271;12101299;12925749;14562106;16847258;17322287;24374639;33491328;9169869;9234674", "class_list": "", "function": "May be involved in endoplasmic reticulum exit trafficking of proteins., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VU88", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane", "go_biological_process": "GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P53174-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53177-1", "uniprot_id": [ { "id": "TYW3_YEAST", "url": "https://www.uniprot.org/uniprot/P53177", "type": "external" } ], "mass": 30806.0, "length": 273, "protein_name": "tRNA wybutosine-synthesizing protein 3", "gene_name": "TYW3", "organism": "Yeast", "refseq_name": "tRNA methyltransferase TYW3", "refseq_ac": [ { "id": "NP_011465", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011465", "type": "external" } ], "gene_names_uniprotkb": "TYW3", "gene_names_refseq": "TYW3", "protein_names_uniprotkb": "tRNA wybutosine-synthesizing protein 3; 2.1.1.282; tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase; tRNA-yW-synthesizing protein 3", "protein_names_refseq": "tRNA methyltransferase TYW3", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL050W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562106;16642040;18407956;19779198;22814378;24374639;33481703;33491328;9169869;9234674", "class_list": "", "function": "S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VU90", "ec_number_list": [ { "id": "2.1.1.282", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.282", "type": "external" } ], "go_molecular_function": "GO:0008175 tRNA methyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006400 tRNA modification;GO:0030488 tRNA methylation;GO:0031591 wybutosine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P53177-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53179-1", "uniprot_id": [ { "id": "PALF_YEAST", "url": "https://www.uniprot.org/uniprot/P53179", "type": "external" } ], "mass": 60864.0, "length": 542, "protein_name": "pH-response regulator protein palF/RIM8", "gene_name": "RIM8", "organism": "Yeast", "refseq_name": "Rim8p", "refseq_ac": [ { "id": "NP_011470", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011470", "type": "external" } ], "gene_names_uniprotkb": "RIM8; PAL3; YGL046W", "gene_names_refseq": "ART9; PAL3; RIM8; YGL046W", "protein_names_uniprotkb": "pH-response regulator protein palF/RIM8; Regulator of IME2 protein 8", "protein_names_refseq": "Rim8p", "tax_id": 559292, "disease": "stomach cancer (Disease Ontology:DOID:10534); Reye syndrome (Disease Ontology:DOID:14525); glaucoma (Disease Ontology:DOID:1686); renal cell carcinoma (Disease Ontology:DOID:4450); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (sce:YGL045W)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10821185;12509465;14562106;17322287;19779198;21126336;22106047;23749301;24374639;32597660;33481703;33491328;9017390;9169869;9234674", "class_list": "", "function": "Required for the proteolytic cleavage of the transcriptional repressor RIM101 in response to alkaline ambient pH, which is necessary for sporulation and invasive growth., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VU94;P53180;Q9URQ4", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0071230 cellular response to amino acid stimulus;GO:0070086 ubiquitin-dependent endocytosis", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P53179-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53183-1", "uniprot_id": [ { "id": "YGD9_YEAST", "url": "https://www.uniprot.org/uniprot/P53183", "type": "external" } ], "mass": 38259.0, "length": 348, "protein_name": "Putative uncharacterized oxidoreductase YGL039W", "gene_name": "", "organism": "Yeast", "refseq_name": "carbonyl reductase (NADPH-dependent)", "refseq_ac": [ { "id": "NP_011476", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011476", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Putative uncharacterized oxidoreductase YGL039W; 1.1.1.-", "protein_names_refseq": "carbonyl reductase (NADPH-dependent)", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL039W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;17322287;19795423;19823750;24374639;9169869", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUA0", "ec_number_list": [], "go_molecular_function": "GO:0016614 oxidoreductase activity, acting on CH-OH group of donors;GO:0004029 aldehyde dehydrogenase (NAD+) activity;GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0004090 carbonyl reductase (NADPH) activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0042180 ketone metabolic process;GO:1901426 response to furfural", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P53183-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53187-1", "uniprot_id": [ { "id": "HOP2_YEAST", "url": "https://www.uniprot.org/uniprot/P53187", "type": "external" } ], "mass": 24479.0, "length": 214, "protein_name": "Homologous-pairing protein 2", "gene_name": "HOP2", "organism": "Yeast", "refseq_name": "Hop2p", "refseq_ac": [ { "id": "NP_011482", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011482", "type": "external" } ], "gene_names_uniprotkb": "HOP2", "gene_names_refseq": "HOP2", "protein_names_uniprotkb": "Homologous-pairing protein 2", "protein_names_refseq": "Hop2p", "tax_id": 559292, "disease": "ovarian dysgenesis 3 (Disease Ontology:DOID:0080495)", "pathway": " (sce:YGL033W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11940665;15249670;24374639;24798326;9169869;9708739", "class_list": "", "function": "Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Stimulates DMC1-dependent homologous strand assimilation required for the resolution of meiotic double-strand breaks., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUA5;O74245", "ec_number_list": [], "go_molecular_function": "GO:0003690 double-stranded DNA binding;GO:0120230 recombinase activator activity", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0120231 DNA recombinase auxiliary factor complex", "go_biological_process": "GO:0007129 homologous chromosome pairing at meiosis;GO:0007131 reciprocal meiotic recombination;GO:0000709 meiotic joint molecule formation;GO:0010774 meiotic strand invasion involved in reciprocal meiotic recombination", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P53187-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53189-1", "uniprot_id": [ { "id": "SCW11_YEAST", "url": "https://www.uniprot.org/uniprot/P53189", "type": "external" } ], "mass": 56447.0, "length": 542, "protein_name": "Probable family 17 glucosidase SCW11", "gene_name": "SCW11", "organism": "Yeast", "refseq_name": "putative glucan endo-1,3-beta-D-glucosidase", "refseq_ac": [ { "id": "NP_011487", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011487", "type": "external" } ], "gene_names_uniprotkb": "SCW11", "gene_names_refseq": "SCW11", "protein_names_uniprotkb": "Probable family 17 glucosidase SCW11; 3.2.1.-; Soluble cell wall protein 11", "protein_names_refseq": "putative glucan endo-1,3-beta-D-glucosidase", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL028C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "14562106;24374639;9169869;9748433", "class_list": "glycogene;glycosylhydrolase", "function": "Involved in cell separation., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VUB0", "ec_number_list": [], "go_molecular_function": "GO:0042973 glucan endo-1,3-beta-D-glucosidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0009986 cell surface;GO:0071944 cell periphery;GO:0009277 fungal-type cell wall", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0071555 cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P53189-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001000.001.10100", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53198-1", "uniprot_id": [ { "id": "ERP6_YEAST", "url": "https://www.uniprot.org/uniprot/P53198", "type": "external" } ], "mass": 25275.0, "length": 216, "protein_name": "Protein ERP6", "gene_name": "ERP6", "organism": "Yeast", "refseq_name": "Erp6p", "refseq_ac": [ { "id": "NP_011513", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011513", "type": "external" } ], "gene_names_uniprotkb": "ERP6", "gene_names_refseq": "ERP6", "protein_names_uniprotkb": "Protein ERP6", "protein_names_refseq": "Erp6p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL002W); (R-SCE-6807878); (R-SCE-6811434)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "10359606;16847258;17322287;21177495;24374639;9169869", "class_list": "", "function": "Involved in vesicular protein trafficking., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUD6;E9P916", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016020 membrane;GO:0030134 COPII-coated ER to Golgi transport vesicle", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P53198-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53200-1", "uniprot_id": [ { "id": "EFM5_YEAST", "url": "https://www.uniprot.org/uniprot/P53200", "type": "external" } ], "mass": 28582.0, "length": 248, "protein_name": "Protein-lysine N-methyltransferase EFM5", "gene_name": "EFM5", "organism": "Yeast", "refseq_name": "protein-lysine N-methyltransferase", "refseq_ac": [ { "id": "NP_011515", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011515", "type": "external" } ], "gene_names_uniprotkb": "EFM5; AML1", "gene_names_refseq": "AML1; EFM5", "protein_names_uniprotkb": "Protein-lysine N-methyltransferase EFM5; 2.1.1.-; Elongation factor methyltransferase 5; N(6)-adenine-specific DNA methyltransferase-like 1", "protein_names_refseq": "protein-lysine N-methyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR001C); (R-SCE-8876725)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "10734188;14562095;14562106;14671320;15225602;19779198;20582239;21126336;21858014;24374639;25446118;33481703;33491328;9169869", "class_list": "", "function": "S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that trimethylates elongation factor 1-alpha (TEF1 and TEF2) at 'Lys-79' (PubMed:25446118). Required for replication of Brome mosaic virus (BMV) (PubMed:14671320)., [UniProtKB, HAMAP, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUD8", "ec_number_list": [ { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" } ], "go_molecular_function": "GO:0003676 nucleic acid binding;GO:0016279 protein-lysine N-methyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0018023 peptidyl-lysine trimethylation", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P53200-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53203-1", "uniprot_id": [ { "id": "PEX31_YEAST", "url": "https://www.uniprot.org/uniprot/P53203", "type": "external" } ], "mass": 52943.0, "length": 462, "protein_name": "Peroxisomal membrane protein PEX31", "gene_name": "PEX31", "organism": "Yeast", "refseq_name": "peroxisome biogenesis protein", "refseq_ac": [ { "id": "NP_011518", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011518", "type": "external" } ], "gene_names_uniprotkb": "PEX31", "gene_names_refseq": "PEX31", "protein_names_uniprotkb": "Peroxisomal membrane protein PEX31; Peroxin-31", "protein_names_refseq": "peroxisome biogenesis protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR004W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "14562095;14562106;16847258;17287358;17330950;19779198;19795423;19823750;21126336;24374639;32597660;33481703;33491328;9169869", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUE1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0071561 nucleus-vacuole junction;GO:0005778 peroxisomal membrane;GO:0005783 endoplasmic reticulum;GO:0071944 cell periphery;GO:0071782 endoplasmic reticulum tubular network", "go_biological_process": "GO:1900063 regulation of peroxisome organization;GO:0007031 peroxisome organization", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P53203-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53206-1", "uniprot_id": [ { "id": "MCY1_YEAST", "url": "https://www.uniprot.org/uniprot/P53206", "type": "external" } ], "mass": 42801.0, "length": 393, "protein_name": "Putative mitochondrial cysteine synthase", "gene_name": "MCY1", "organism": "Yeast", "refseq_name": "putative cysteine synthase", "refseq_ac": [ { "id": "NP_011526", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011526", "type": "external" } ], "gene_names_uniprotkb": "MCY1", "gene_names_refseq": "MCY1; TCD3", "protein_names_uniprotkb": "Putative mitochondrial cysteine synthase; 2.5.1.47; CSl; CS; Cysteine synthase-like protein; O-acetylserine (thiol)-lyase; O-acetylserine sulfhydrylase; OAS-TL", "protein_names_refseq": "putative cysteine synthase", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR012W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;14562106;16407407;17482430;19795423;19823750;24374639;9169869;9290212;9409150", "class_list": "", "function": "Putative cysteine synthase that catalyzes the conversion of O-acetyl-L-serine (OAS) into cysteine, the last step in the cysteine biosynthesis pathway. However, this CS-like protein is unlikely to function in cysteine biosynthesis. It seems that in S.cerevisiae cysteine biosynthesis occurs exclusively through the cystathionine pathway and not via direct incorporation of sulfur into OAS., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUE8", "ec_number_list": [ { "id": "2.5.1.47", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.47", "type": "external" }, { "id": "2.5.1.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.49", "type": "external" } ], "go_molecular_function": "GO:0004124 cysteine synthase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0006535 cysteine biosynthetic process from serine", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P53206-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53214-1", "uniprot_id": [ { "id": "MTL1_YEAST", "url": "https://www.uniprot.org/uniprot/P53214", "type": "external" } ], "mass": 57528.0, "length": 551, "protein_name": "Protein MTL1", "gene_name": "MTL1", "organism": "Yeast", "refseq_name": "Mtl1p", "refseq_ac": [ { "id": "NP_011537", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011537", "type": "external" } ], "gene_names_uniprotkb": "MTL1", "gene_names_refseq": "MTL1", "protein_names_uniprotkb": "Protein MTL1; MID two-like protein 1", "protein_names_refseq": "Mtl1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR023W)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "10330137;10348843;11779787;12399379;15637049;16273108;19779198;20702584;21126336;21177495;22218487;23749301;24374639;32597660;33481703;33491328;9169869;9290212", "class_list": "", "function": "Involved in cell integrity signaling during vegetative growth at elevated temperature. Acts positively on the PKC1-MAPK pathway. Cell membrane sensor of oxidative stress in the cell integrity pathway upstream of PKC1. Required to transmit the oxidative signal to SLT2 and to restore the correct actin organization following oxidative stress. Multicopy suppressor of 1,3-beta-glucan synthase (GS) mutation. Also suppresses RGD1 null mutations., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VUF7;Q45U60", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005773 vacuole", "go_biological_process": "GO:0034599 cellular response to oxidative stress;GO:0042149 cellular response to glucose starvation;GO:0007039 protein catabolic process in the vacuole;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P53214-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53215-1", "uniprot_id": [ { "id": "THG1_YEAST", "url": "https://www.uniprot.org/uniprot/P53215", "type": "external" } ], "mass": 27757.0, "length": 237, "protein_name": "tRNA(His) guanylyltransferase", "gene_name": "THG1", "organism": "Yeast", "refseq_name": "tRNA guanylyltransferase", "refseq_ac": [ { "id": "NP_011538", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011538", "type": "external" } ], "gene_names_uniprotkb": "THG1", "gene_names_refseq": "THG1", "protein_names_uniprotkb": "tRNA(His) guanylyltransferase; 2.7.7.79; tRNA-histidine guanylyltransferase", "protein_names_refseq": "tRNA guanylyltransferase", "tax_id": 559292, "disease": "autosomal recessive cerebellar ataxia (Disease Ontology:DOID:0050950); autosomal recessive spinocerebellar ataxia 28 (Disease Ontology:DOID:0070409); cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YGR024C)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "14562106;14633974;16273108;16625026;16731615;17322287;18366186;22814378;24374639;24548272;28623126;33790044;9169869;9290212", "class_list": "", "function": "Acts as a tRNA(His) guanylyltransferase that catalyzes 3'-5' addition of a single guanosine residue to the -1 position of tRNA(His), to form a non-Watson-Crick G(-1):A-73 base pair (PubMed:14633974, PubMed:16625026, PubMed:18366186, PubMed:24548272, PubMed:33790044). After addition of G(-1), THG1 removes pyrophosphate from the tRNA 5'-end, generating 5'-monophosphorylated G(-1)-containing tRNA which is important for recognition of tRNA(His) by its cognate histidyl-tRNA synthetase (PubMed:24548272). In addition to the single-G(-1) addition reaction, THG1 polymerizes multiple G residues to the 5'-end of tRNA(His) variants using the 3'-end of the tRNA(His) acceptor stem as a template (PubMed:16731615, PubMed:24548272, PubMed:33790044)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 17, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUF8;Q45U59", "ec_number_list": [ { "id": "2.7.7.79", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.79", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005525 GTP binding;GO:0042802 identical protein binding;GO:0008193 tRNA guanylyltransferase activity;GO:0097748 3'-5' RNA polymerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0008033 tRNA processing;GO:0006400 tRNA modification", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P53215-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53219-1", "uniprot_id": [ { "id": "IMO32_YEAST", "url": "https://www.uniprot.org/uniprot/P53219", "type": "external" } ], "mass": 38511.0, "length": 342, "protein_name": "Probable alcohol acetyltransferase", "gene_name": "IMO32", "organism": "Yeast", "refseq_name": "Imo32p", "refseq_ac": [ { "id": "NP_011545", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011545", "type": "external" } ], "gene_names_uniprotkb": "IMO32", "gene_names_refseq": "IMO32", "protein_names_uniprotkb": "Probable alcohol acetyltransferase; 2.3.1.-; AAT; Intermediate cleaved by mitochondrial octapeptidyl aminopeptidase protein 32", "protein_names_refseq": "Imo32p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR031W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;14562106;16273108;16823961;17322287;21525245;24374639;28356220;9169869;9290212", "class_list": "", "function": "Probable alcohol acetyltransferase that uses acetyl-CoA to synthesize acetate esters from various alcohols (Probable). Not involved in the synthesis of ethyl acetate (PubMed:28356220)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUG6;Q45U54", "ec_number_list": [], "go_molecular_function": "GO:0052689 carboxylic ester hydrolase activity;GO:0016740 transferase activity;GO:0004806 triacylglycerol lipase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P53219-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53221-1", "uniprot_id": [ { "id": "RL26B_YEAST", "url": "https://www.uniprot.org/uniprot/P53221", "type": "external" } ], "mass": 14235.0, "length": 127, "protein_name": "Large ribosomal subunit protein uL24B", "gene_name": "RPL26B", "organism": "Yeast", "refseq_name": "60S ribosomal protein uL24 RPL26B", "refseq_ac": [ { "id": "NP_011548", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011548", "type": "external" } ], "gene_names_uniprotkb": "RPL26B; RPL33B", "gene_names_refseq": "RPL26B", "protein_names_uniprotkb": "Large ribosomal subunit protein uL24B; 60S ribosomal protein L26-B; L33; YL33", "protein_names_refseq": "60S ribosomal protein uL24 RPL26B", "tax_id": 559292, "disease": "Diamond-Blackfan anemia 11 (Disease Ontology:DOID:0111892)", "pathway": " (sce:YGR034W); (R-SCE-156827); (R-SCE-1799339); (R-SCE-72689); (R-SCE-72706); (R-SCE-975956); (R-SCE-975957); (R-SCE-9954709); (R-SCE-9954714)", "pathway_count": 9, "publication_count": 20, "publication_id_list": "14562095;14562106;16273108;17101987;17287358;17351133;18782943;19779198;19795423;19823750;22096102;23749301;24374639;24524803;32597660;33481703;33491328;9169869;9290212;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUH0;Q06HN2;Q45U50", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0042273 ribosomal large subunit biogenesis;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P53221-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53226-1", "uniprot_id": [ { "id": "BUD9_YEAST", "url": "https://www.uniprot.org/uniprot/P53226", "type": "external" } ], "mass": 60751.0, "length": 547, "protein_name": "Bud site selection protein 9", "gene_name": "BUD9", "organism": "Yeast", "refseq_name": "Bud9p", "refseq_ac": [ { "id": "NP_011555", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011555", "type": "external" } ], "gene_names_uniprotkb": "BUD9; G4152", "gene_names_refseq": "BUD9", "protein_names_uniprotkb": "Bud site selection protein 9", "protein_names_refseq": "Bud9p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR041W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "11514631;14562106;15356260;16847258;18407956;19779198;20678480;21625000;23749301;24374639;32597660;33481703;33491328;8657162;9169869;9290212", "class_list": "", "function": "May be involved in positioning the proximal bud pole signal., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 9, "predicted_n_glycosites": 9, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 17, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "D6VUH9;Q9HFS8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005934 cellular bud tip;GO:0005935 cellular bud neck", "go_biological_process": "GO:0000282 cellular bud site selection", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P53226-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53228-1", "uniprot_id": [ { "id": "TAL2_YEAST", "url": "https://www.uniprot.org/uniprot/P53228", "type": "external" } ], "mass": 37254.0, "length": 333, "protein_name": "Transaldolase NQM1", "gene_name": "NQM1", "organism": "Yeast", "refseq_name": "sedoheptulose-7-phosphate:D-glyceraldehyde-3- phosphate transaldolase NQM1", "refseq_ac": [ { "id": "NP_011557", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011557", "type": "external" } ], "gene_names_uniprotkb": "NQM1", "gene_names_refseq": "NQM1", "protein_names_uniprotkb": "Transaldolase NQM1; 2.2.1.2; Non-quiescent mutant protein 1", "protein_names_refseq": "sedoheptulose-7-phosphate:D-glyceraldehyde-3- phosphate transaldolase NQM1", "tax_id": 559292, "disease": "carbohydrate metabolic disorder (Disease Ontology:DOID:2978)", "pathway": " (sce:YGR043C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;17322287;18407956;18831051;24374639;33491328;9169869;9290212", "class_list": "", "function": "Transaldolase involved in the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedoheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate. Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUI1;Q6Q5P8", "ec_number_list": [ { "id": "2.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.2.1.2", "type": "external" } ], "go_molecular_function": "GO:0004801 transaldolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0009052 pentose-phosphate shunt, non-oxidative branch;GO:0005975 carbohydrate metabolic process;GO:0034599 cellular response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P53228-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53235-1", "uniprot_id": [ { "id": "EIF2A_YEAST", "url": "https://www.uniprot.org/uniprot/P53235", "type": "external" } ], "mass": 71305.0, "length": 642, "protein_name": "Eukaryotic translation initiation factor 2A", "gene_name": "", "organism": "Yeast", "refseq_name": "translation initiation factor 2A", "refseq_ac": [ { "id": "NP_011568", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011568", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 2A; eIF-2A", "protein_names_refseq": "translation initiation factor 2A", "tax_id": 559292, "disease": "borna disease (Disease Ontology:DOID:5154)", "pathway": " (sce:YGR054W)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "12133843;15718232;16273108;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;23749301;24374639;30516470;32597660;33481703;33491328;9169869", "class_list": "", "function": "Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. Specifically associates with both 40S subunits and 80S ribosomes., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VUI9;Q45U32", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0000049 tRNA binding;GO:0043022 ribosome binding;GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0022626 cytosolic ribosome;GO:0005850 eukaryotic translation initiation factor 2 complex", "go_biological_process": "GO:0006413 translational initiation;GO:0017148 negative regulation of translation", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P53235-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53237-1", "uniprot_id": [ { "id": "LST7_YEAST", "url": "https://www.uniprot.org/uniprot/P53237", "type": "external" } ], "mass": 28136.0, "length": 242, "protein_name": "Protein LST7", "gene_name": "LST7", "organism": "Yeast", "refseq_name": "Lst7p", "refseq_ac": [ { "id": "NP_011571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011571", "type": "external" } ], "gene_names_uniprotkb": "LST7", "gene_names_refseq": "LST7", "protein_names_uniprotkb": "Protein LST7; Lethal with SEC thirteen protein 7", "protein_names_refseq": "Lst7p", "tax_id": 559292, "disease": "nonpapillary renal cell carcinoma (Disease Ontology:DOID:0050387); Birt-Hogg-Dube syndrome (Disease Ontology:DOID:0050676); primary spontaneous pneumothorax (Disease Ontology:DOID:0080218); renal cell carcinoma (Disease Ontology:DOID:4450); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (sce:YGR057C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12748633;14562106;16273108;24374639;32801125;9169869;9409822", "class_list": "", "function": "Required for the nitrogen-regulated transport of amino acid permeases GAP1 and PUT4 from the Golgi to the cell surface., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUJ2;Q45U29", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005774 vacuolar membrane;GO:1990877 FNIP-folliculin RagC/D GAP", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0071230 cellular response to amino acid stimulus", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P53237-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53239-1", "uniprot_id": [ { "id": "COX18_YEAST", "url": "https://www.uniprot.org/uniprot/P53239", "type": "external" } ], "mass": 35650.0, "length": 316, "protein_name": "Cytochrome c oxidase assembly protein COX18, mitochondrial", "gene_name": "COX18", "organism": "Yeast", "refseq_name": "membrane insertase COX18", "refseq_ac": [ { "id": "NP_011576", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011576", "type": "external" } ], "gene_names_uniprotkb": "COX18; G4532", "gene_names_refseq": "COX18; OXA2", "protein_names_uniprotkb": "Cytochrome c oxidase assembly protein COX18, mitochondrial; Cytochrome c oxidase assembly protein 18", "protein_names_refseq": "membrane insertase COX18", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR062C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10809734;11950926;14562106;24374639;9169869", "class_list": "", "function": "Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome c oxidase. Plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VUJ7", "ec_number_list": [], "go_molecular_function": "GO:0032977 membrane insertase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0033617 mitochondrial respiratory chain complex IV assembly;GO:0032979 protein insertion into mitochondrial inner membrane from matrix", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P53239-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53241-1", "uniprot_id": [ { "id": "VHT1_YEAST", "url": "https://www.uniprot.org/uniprot/P53241", "type": "external" } ], "mass": 69083.0, "length": 593, "protein_name": "Vitamin H transporter", "gene_name": "VHT1", "organism": "Yeast", "refseq_name": "Vht1p", "refseq_ac": [ { "id": "NP_011579", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011579", "type": "external" } ], "gene_names_uniprotkb": "VHT1", "gene_names_refseq": "VHT1", "protein_names_uniprotkb": "Vitamin H transporter; H(+)/biotin symporter", "protein_names_refseq": "Vht1p", "tax_id": 559292, "disease": "autosomal dominant nonsyndromic deafness 25 (Disease Ontology:DOID:0110555); lysosomal storage disease (Disease Ontology:DOID:3211); sialuria (Disease Ontology:DOID:3659)", "pathway": " (sce:YGR065C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10373489;16847258;19779198;19795423;19823750;24374639;32597660;33491328;9169869", "class_list": "", "function": "Involved in uptake of biotin with the concomitant entry of protons., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUJ9", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015293 symporter activity;GO:0015225 biotin transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0015878 biotin transport", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P53241-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53242-1", "uniprot_id": [ { "id": "GID10_YEAST", "url": "https://www.uniprot.org/uniprot/P53242", "type": "external" } ], "mass": 34048.0, "length": 292, "protein_name": "GID complex substrate-recognition subunit 10", "gene_name": "GID10", "organism": "Yeast", "refseq_name": "Gid10p", "refseq_ac": [ { "id": "NP_011580", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011580", "type": "external" } ], "gene_names_uniprotkb": "GID10", "gene_names_refseq": "GID10", "protein_names_uniprotkb": "GID complex substrate-recognition subunit 10; Glucose-induced degradation protein 10", "protein_names_refseq": "Gid10p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR066C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "16273108;17322287;24374639;31337681;31708416;34695755;34767800;35437932;9169869", "class_list": "", "function": "Substrate-recognition component of the GID E3 ligase complex recruiting N termini and catalyzing ubiquitination of proteins targeted for degradation. GID E3 is regulated through assembly with interchangeable N-degron-binding substrate receptors induced by distinct environmental perturbations (PubMed:31708416). Required for the adaptation to osmotic or heat stress (PubMed:31708416). Required for the regulation of protein levels of the adapter protein ART2, a component of the ART-Rsp5 ubiquitin ligase pathway, part of the plasma membrane quality control (PubMed:35437932). Specific for substrates with an N-terminal Pro (Pro/N-degron), including ART2 (PubMed:31337681, PubMed:35437932). Has high affinity for the N-terminal sequence Pro-Tyr-Ile-Thr, and also recognizes nonproline residues such as Met-Tyr-Ile-Thr-Val or Val-Cys-Phe-His (PubMed:31337681, PubMed:34695755)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUK0;Q45U21;Q6B2W2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005773 vacuole;GO:0034657 GID complex", "go_biological_process": "GO:0006970 response to osmotic stress;GO:0042594 response to starvation;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045721 negative regulation of gluconeogenesis;GO:0030163 protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P53242-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53246-1", "uniprot_id": [ { "id": "ENV11_YEAST", "url": "https://www.uniprot.org/uniprot/P53246", "type": "external" } ], "mass": 98109.0, "length": 860, "protein_name": "Late endosome and vacuole interface protein 11", "gene_name": "ENV11", "organism": "Yeast", "refseq_name": "Env11p", "refseq_ac": [ { "id": "NP_011585", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011585", "type": "external" } ], "gene_names_uniprotkb": "ENV11", "gene_names_refseq": "ENV11", "protein_names_uniprotkb": "Late endosome and vacuole interface protein 11", "protein_names_refseq": "Env11p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR071C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12096123;14562095;14562106;19466415;21912603;24374639;33481703;33491328;9169869", "class_list": "", "function": "Involved in vacuolar processing and morphology., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUK4", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005773 vacuole", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0007033 vacuole organization;GO:0006624 vacuolar protein processing", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P53246-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53248-1", "uniprot_id": [ { "id": "PEX8_YEAST", "url": "https://www.uniprot.org/uniprot/P53248", "type": "external" } ], "mass": 68165.0, "length": 589, "protein_name": "Peroxisomal biogenesis factor 8", "gene_name": "PEX8", "organism": "Yeast", "refseq_name": "Pex8p", "refseq_ac": [ { "id": "NP_011591", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011591", "type": "external" } ], "gene_names_uniprotkb": "PEX8; PAS6", "gene_names_refseq": "PAS6; PEX8", "protein_names_uniprotkb": "Peroxisomal biogenesis factor 8; Peroxin-8; Peroxisomal protein PAS6", "protein_names_refseq": "Pex8p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR077C)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "14562106;24374639;9169869", "class_list": "", "function": "Required for peroxisome assembly., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUK9", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:1990429 peroxisomal importomer complex;GO:0005782 peroxisomal matrix", "go_biological_process": "GO:0016558 protein import into peroxisome matrix", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P53248-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53257-1", "uniprot_id": [ { "id": "TPC1_YEAST", "url": "https://www.uniprot.org/uniprot/P53257", "type": "external" } ], "mass": 35137.0, "length": 314, "protein_name": "Mitochondrial thiamine pyrophosphate carrier 1", "gene_name": "TPC1", "organism": "Yeast", "refseq_name": "thiamine transporter TPC1", "refseq_ac": [ { "id": "NP_011610", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011610", "type": "external" } ], "gene_names_uniprotkb": "TPC1", "gene_names_refseq": "TPC1", "protein_names_uniprotkb": "Mitochondrial thiamine pyrophosphate carrier 1", "protein_names_refseq": "thiamine transporter TPC1", "tax_id": 559292, "disease": "microcephaly (Disease Ontology:DOID:10907); inherited metabolic disorder (Disease Ontology:DOID:655)", "pathway": " (sce:YGR096W); (R-SCE-196819)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "10930523;12411483;14562095;17322287;22814378;24374639;9169869;9178508", "class_list": "", "function": "Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUM8;Q6B1H1", "ec_number_list": [], "go_molecular_function": "GO:0090422 thiamine pyrophosphate transmembrane transporter activity;GO:0015234 thiamine transmembrane transporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0030974 thiamine pyrophosphate transmembrane transport;GO:1990545 mitochondrial thiamine pyrophosphate transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P53257-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53258-1", "uniprot_id": [ { "id": "GYP2_YEAST", "url": "https://www.uniprot.org/uniprot/P53258", "type": "external" } ], "mass": 109259.0, "length": 950, "protein_name": "GTPase-activating protein GYP2", "gene_name": "MDR1", "organism": "Yeast", "refseq_name": "GTPase-activating protein MDR1", "refseq_ac": [ { "id": "NP_011614", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011614", "type": "external" } ], "gene_names_uniprotkb": "MDR1; G5717; GYP2; MIC1", "gene_names_refseq": "GYP2; MDR1; MIC1", "protein_names_uniprotkb": "GTPase-activating protein GYP2; MAC1-dependent regulator; Protein MIC1", "protein_names_refseq": "GTPase-activating protein MDR1", "tax_id": 559292, "disease": "nephrotic syndrome type 20 (Disease Ontology:DOID:0070357)", "pathway": " (sce:YGR100W)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "10559187;12807768;14562095;14562106;15574876;17330950;18407956;19779198;19795423;19823750;21177495;22814378;23749301;24374639;32597660;33481703;33491328;9169869", "class_list": "", "function": "Stimulates specifically the GTPase activity of SEC4, YPT6 and YPT36. Inactivates YPT6 during recycling between the endosome and the Golgi compartments., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 18, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUN2", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0043332 mating projection tip", "go_biological_process": "GO:0090630 activation of GTPase activity", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P53258-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53260-1", "uniprot_id": [ { "id": "GATF_YEAST", "url": "https://www.uniprot.org/uniprot/P53260", "type": "external" } ], "mass": 20787.0, "length": 183, "protein_name": "Glutamyl-tRNA(Gln) amidotransferase subunit F, mitochondrial", "gene_name": "GTF1", "organism": "Yeast", "refseq_name": "glutamyl-tRNA(Gln) amidotransferase subunit F", "refseq_ac": [ { "id": "NP_011616", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011616", "type": "external" } ], "gene_names_uniprotkb": "GTF1", "gene_names_refseq": "GTF1", "protein_names_uniprotkb": "Glutamyl-tRNA(Gln) amidotransferase subunit F, mitochondrial; 6.3.5.-; Glu-AdT subunit F", "protein_names_refseq": "glutamyl-tRNA(Gln) amidotransferase subunit F", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR102C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;16823961;17322287;19417106;21799017;24374639;9169869", "class_list": "", "function": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for proper protein synthesis within the mitochondrion., [UniProtKB, PubMed, HAMAP, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUN4;Q6Q591", "ec_number_list": [ { "id": "6.3.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.5.-", "type": "external" }, { "id": "6.3.5.7", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.5.7", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex", "go_biological_process": "GO:0032543 mitochondrial translation;GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P53260-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53266-1", "uniprot_id": [ { "id": "SHY1_YEAST", "url": "https://www.uniprot.org/uniprot/P53266", "type": "external" } ], "mass": 45056.0, "length": 389, "protein_name": "Cytochrome oxidase assembly protein SHY1", "gene_name": "SHY1", "organism": "Yeast", "refseq_name": "cytochrome oxidase assembly protein SHY1", "refseq_ac": [ { "id": "NP_011627", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011627", "type": "external" } ], "gene_names_uniprotkb": "SHY1; G6150", "gene_names_refseq": "SHY1", "protein_names_uniprotkb": "Cytochrome oxidase assembly protein SHY1; SURF1 homolog of Yeast; SURF1-like protein", "protein_names_refseq": "cytochrome oxidase assembly protein SHY1", "tax_id": 559292, "disease": "mitochondrial complex IV deficiency nuclear type 1 (Disease Ontology:DOID:0070491); Charcot-Marie-Tooth disease type 4K (Disease Ontology:DOID:0110187); Leigh disease (Disease Ontology:DOID:3652)", "pathway": " (sce:YGR112W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "11782424;14562095;14562106;14576278;17882259;17882260;18541668;24374639;8905931;9162072;9169869", "class_list": "", "function": "Required for efficient assembly of cytochrome c oxidase in the mitochondrial inner membrane. Involved in a step that couples MSS51-COX14-dependent regulation of COX1 translation to early steps of cytochrome c oxidase assembly., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUP5", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005777 peroxisome;GO:0016020 membrane", "go_biological_process": "GO:0033617 mitochondrial respiratory chain complex IV assembly", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P53266-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53279-1", "uniprot_id": [ { "id": "FHN1_YEAST", "url": "https://www.uniprot.org/uniprot/P53279", "type": "external" } ], "mass": 19152.0, "length": 174, "protein_name": "Non-classical export protein 2 homolog 1", "gene_name": "FHN1", "organism": "Yeast", "refseq_name": "Fhn1p", "refseq_ac": [ { "id": "NP_011647", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011647", "type": "external" } ], "gene_names_uniprotkb": "FHN1", "gene_names_refseq": "FHN1", "protein_names_uniprotkb": "Non-classical export protein 2 homolog 1; Functional homolog of NCE102", "protein_names_refseq": "Fhn1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR131W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12824174;16847258;20581291;24374639;9169869", "class_list": "", "function": "Involved in membrane organization. Required for the formation of membrane compartments of CAN1 (MCCs), localization of CAN1 at the MCCs and subsequent invagination of the plasma membrane at the MCCs sites. Involved in eisosome organization and might act as a sensor of sphingolipids that regulates plasma membrane function. Involved in a novel pathway of export of proteins that lack a cleavable signal sequence. Non-classical export pathway also functions as an alternative clearance/detoxification pathway to eliminate damaged material, when the basic repair pathway is not sufficient., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUR3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0032126 eisosome", "go_biological_process": "GO:0015031 protein transport;GO:0072659 protein localization to plasma membrane;GO:0070941 eisosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P53279-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53283-1", "uniprot_id": [ { "id": "TPO2_YEAST", "url": "https://www.uniprot.org/uniprot/P53283", "type": "external" } ], "mass": 67589.0, "length": 614, "protein_name": "Polyamine transporter 2", "gene_name": "TPO2", "organism": "Yeast", "refseq_name": "spermine transporter", "refseq_ac": [ { "id": "NP_011654", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011654", "type": "external" } ], "gene_names_uniprotkb": "TPO2; G6417", "gene_names_refseq": "TPO2", "protein_names_uniprotkb": "Polyamine transporter 2", "protein_names_refseq": "spermine transporter", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR138C)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "11171066;11875433;12562762;14562095;15066780;16847258;17330950;17563356;18407956;19779198;21177495;22218487;23749301;24374639;32597660;33481703;33491328;34965436;9169869", "class_list": "", "function": "Cell membrane polyamine/proton antiporter, involved in the detoxification of excess polyamines in the cytoplasm. Recognizes spermine, but not spermidine., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUR9", "ec_number_list": [], "go_molecular_function": "GO:0015297 antiporter activity;GO:0000297 spermine transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0000296 spermine transport;GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P53283-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53285-1", "uniprot_id": [ { "id": "VPS62_YEAST", "url": "https://www.uniprot.org/uniprot/P53285", "type": "external" } ], "mass": 54515.0, "length": 467, "protein_name": "Vacuolar protein sorting-associated protein 62", "gene_name": "VPS62", "organism": "Yeast", "refseq_name": "Vps62p", "refseq_ac": [ { "id": "NP_011657", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011657", "type": "external" } ], "gene_names_uniprotkb": "VPS62", "gene_names_refseq": "VPS62", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 62", "protein_names_refseq": "Vps62p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR141W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12134085;14562106;24374639;9169869", "class_list": "", "function": "Involved in vacuolar protein sorting., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VUS1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0006623 protein targeting to vacuole", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P53285-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53289-1", "uniprot_id": [ { "id": "RTS3_YEAST", "url": "https://www.uniprot.org/uniprot/P53289", "type": "external" } ], "mass": 29263.0, "length": 263, "protein_name": "Protein phosphatase type 2A regulatory subunit RTS3", "gene_name": "RTS3", "organism": "Yeast", "refseq_name": "Rts3p", "refseq_ac": [ { "id": "NP_011677", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011677", "type": "external" } ], "gene_names_uniprotkb": "RTS3", "gene_names_refseq": "RTS3", "protein_names_uniprotkb": "Protein phosphatase type 2A regulatory subunit RTS3", "protein_names_refseq": "Rts3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR161C)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "14562095;14562106;14566057;16713564;17563356;18407956;19684113;19779198;20489023;20702584;21126336;21177495;21360731;23749301;24374639;32597660;33481703;33491328;9169869;9290212", "class_list": "", "function": "May be a component of a protein phosphatase type 2A (PP2A) complex. Negatively regulates SIT4 phosphatase, a modulators of caffeine sensitivity., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 28, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUU0;Q7ZA12", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P53289-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53292-1", "uniprot_id": [ { "id": "RT35_YEAST", "url": "https://www.uniprot.org/uniprot/P53292", "type": "external" } ], "mass": 39575.0, "length": 345, "protein_name": "Small ribosomal subunit protein mS45", "gene_name": "MRPS35", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein mS45 MRPS35", "refseq_ac": [ { "id": "NP_011681", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011681", "type": "external" } ], "gene_names_uniprotkb": "MRPS35", "gene_names_refseq": "MRPS35; mS45", "protein_names_uniprotkb": "Small ribosomal subunit protein mS45; 37S ribosomal protein S35, mitochondrial", "protein_names_refseq": "mitochondrial 37S ribosomal protein mS45 MRPS35", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR165W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "12392552;14562095;14562106;16823961;17322287;24374639;25609543;28154081;33491328;9169869;9290212", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUU8", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P53292-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53304-1", "uniprot_id": [ { "id": "SLI1_YEAST", "url": "https://www.uniprot.org/uniprot/P53304", "type": "external" } ], "mass": 54473.0, "length": 468, "protein_name": "N-acetyltransferase SLI1", "gene_name": "SLI1", "organism": "Yeast", "refseq_name": "N-acetyltransferase", "refseq_ac": [ { "id": "NP_011728", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011728", "type": "external" } ], "gene_names_uniprotkb": "SLI1", "gene_names_refseq": "SLI1", "protein_names_uniprotkb": "N-acetyltransferase SLI1; 2.3.1.-; Sphingosine-like immunosuppressant resistant protein 1", "protein_names_refseq": "N-acetyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR212W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15025559;24374639;9169869;9290212", "class_list": "", "function": "Confers resistance to the sphingolipid biosynthesis inhibitor drug myriocin (ISP-1). Inactivates ISP-1 by converting it into N-acetyl-myriocin. Cooperates with YPK1 in mediating resistance to myriocin., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUZ5", "ec_number_list": [], "go_molecular_function": "GO:0008080 N-acetyltransferase activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane", "go_biological_process": "GO:0009410 response to xenobiotic stimulus", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P53304-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53305-1", "uniprot_id": [ { "id": "RT27_YEAST", "url": "https://www.uniprot.org/uniprot/P53305", "type": "external" } ], "mass": 12393.0, "length": 110, "protein_name": "Small ribosomal subunit protein mS33", "gene_name": "RSM27", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein mS33 RSM27", "refseq_ac": [ { "id": "NP_011731", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011731", "type": "external" } ], "gene_names_uniprotkb": "RSM27", "gene_names_refseq": "RSM27; mS33", "protein_names_uniprotkb": "Small ribosomal subunit protein mS33; Mitochondrial 37S ribosomal protein S27", "protein_names_refseq": "mitochondrial 37S ribosomal protein mS33 RSM27", "tax_id": 559292, "disease": "intrinsic cardiomyopathy (Disease Ontology:DOID:0060036)", "pathway": " (sce:YGR215W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "11278769;12392552;14562095;14576278;17322287;22814378;24374639;25609543;28154081;9169869;9290212", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUZ8", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P53305-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53306-1", "uniprot_id": [ { "id": "GPI1_YEAST", "url": "https://www.uniprot.org/uniprot/P53306", "type": "external" } ], "mass": 70354.0, "length": 609, "protein_name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI1", "gene_name": "GPI1", "organism": "Yeast", "refseq_name": "phosphatidylinositol N-acetylglucosaminyltransferase", "refseq_ac": [ { "id": "NP_011732", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011732", "type": "external" } ], "gene_names_uniprotkb": "GPI1", "gene_names_refseq": "GPI1", "protein_names_uniprotkb": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI1; 2.4.1.198; GPI-GlcNAc transferase complex subunit GPI1; GPI-GnT subunit GPI1", "protein_names_refseq": "phosphatidylinositol N-acetylglucosaminyltransferase", "tax_id": 559292, "disease": "multiple congenital anomalies-hypotonia-seizures syndrome 4 (Disease Ontology:DOID:0112213)", "pathway": " (sce:YGR216C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "15163411;16847258;24374639;8910381;9169869;9290212", "class_list": "glycogene;glycosyltransferase", "function": "Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUZ9", "ec_number_list": [ { "id": "2.4.1.198", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.198", "type": "external" } ], "go_molecular_function": "GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006506 GPI anchor biosynthetic process;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P53306-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53312-1", "uniprot_id": [ { "id": "SUCB_YEAST", "url": "https://www.uniprot.org/uniprot/P53312", "type": "external" } ], "mass": 46901.0, "length": 427, "protein_name": "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "gene_name": "LSC2", "organism": "Yeast", "refseq_name": "succinate--CoA ligase (GDP-forming) subunit beta", "refseq_ac": [ { "id": "NP_011760", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011760", "type": "external" } ], "gene_names_uniprotkb": "LSC2; G8625", "gene_names_refseq": "LSC2", "protein_names_uniprotkb": "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; 6.2.1.5; SCS-beta; Succinyl-CoA synthetase beta chain", "protein_names_refseq": "succinate--CoA ligase (GDP-forming) subunit beta", "tax_id": 559292, "disease": "mitochondrial DNA depletion syndrome 5 (Disease Ontology:DOID:0080124)", "pathway": " (sce:YGR244C); (R-SCE-71403)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "14576278;17330950;18407956;19684113;19779198;20190278;23749301;24374639;32597660;33481703;33491328;9090057;9169869;9874242", "class_list": "", "function": "Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA (PubMed:9874242). The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit (By similarity)., [UniProtKB, HAMAP, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV24", "ec_number_list": [ { "id": "6.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.5", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0004775 succinate-CoA ligase (ADP-forming) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0042709 succinate-CoA ligase complex", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006104 succinyl-CoA metabolic process;GO:1901289 succinyl-CoA catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P53312-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53313-1", "uniprot_id": [ { "id": "SDA1_YEAST", "url": "https://www.uniprot.org/uniprot/P53313", "type": "external" } ], "mass": 86618.0, "length": 767, "protein_name": "Protein SDA1", "gene_name": "SDA1", "organism": "Yeast", "refseq_name": "Sda1p", "refseq_ac": [ { "id": "NP_011761", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011761", "type": "external" } ], "gene_names_uniprotkb": "SDA1", "gene_names_refseq": "SDA1", "protein_names_uniprotkb": "Protein SDA1; Severe depolymerization of actin protein 1", "protein_names_refseq": "Sda1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR245C)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "10704371;11160833;11583615;12374754;14562106;15107621;15116429;16541108;17330950;17563356;19779198;19795423;19823750;20702584;22218487;23749301;24374639;33481703;33491328;9133742;9169869", "class_list": "", "function": "Required for 60S pre-ribosomal subunits export to the cytoplasm. May also be required for 60S ribosomal subunit maturation and accumulation. Involved in G1 events and passage through start, and possibly actin cytoskeleton organization., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV25", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus", "go_biological_process": "GO:0000055 ribosomal large subunit export from nucleus;GO:0015031 protein transport;GO:0042273 ribosomal large subunit biogenesis;GO:0007089 traversing start control point of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P53313-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53315-1", "uniprot_id": [ { "id": "SOL4_YEAST", "url": "https://www.uniprot.org/uniprot/P53315", "type": "external" } ], "mass": 28448.0, "length": 255, "protein_name": "6-phosphogluconolactonase 4", "gene_name": "SOL4", "organism": "Yeast", "refseq_name": "6-phosphogluconolactonase SOL4", "refseq_ac": [ { "id": "NP_011764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011764", "type": "external" } ], "gene_names_uniprotkb": "SOL4", "gene_names_refseq": "SOL4", "protein_names_uniprotkb": "6-phosphogluconolactonase 4; 3.1.1.31; 6PGL", "protein_names_refseq": "6-phosphogluconolactonase SOL4", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR248W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;15454531;24374639;33491328;9133742;9169869", "class_list": "", "function": "Involved in the pentose phosphate pathway via hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV28", "ec_number_list": [ { "id": "3.1.1.31", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.31", "type": "external" } ], "go_molecular_function": "GO:0017057 6-phosphogluconolactonase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0009051 pentose-phosphate shunt, oxidative branch", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P53315-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53316-1", "uniprot_id": [ { "id": "YG5B_YEAST", "url": "https://www.uniprot.org/uniprot/P53316", "type": "external" } ], "mass": 89513.0, "length": 781, "protein_name": "Uncharacterized RNA-binding protein YGR250C", "gene_name": "", "organism": "Yeast", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized RNA-binding protein YGR250C", "protein_names_refseq": "", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR250C)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "14562106;15665377;17330950;17563356;18407956;19448108;19779198;20702584;21126336;21177495;23749301;24374639;30516470;32597660;33481703;33491328;9133742;9169869", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 28, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV30", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:2000134 negative regulation of G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P53316-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53319-1", "uniprot_id": [ { "id": "6PGD2_YEAST", "url": "https://www.uniprot.org/uniprot/P53319", "type": "external" } ], "mass": 53923.0, "length": 492, "protein_name": "6-phosphogluconate dehydrogenase, decarboxylating 2", "gene_name": "GND2", "organism": "Yeast", "refseq_name": "phosphogluconate dehydrogenase (decarboxylating) GND2", "refseq_ac": [ { "id": "NP_011772", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011772", "type": "external" } ], "gene_names_uniprotkb": "GND2; G9170", "gene_names_refseq": "GND2", "protein_names_uniprotkb": "6-phosphogluconate dehydrogenase, decarboxylating 2; 1.1.1.44", "protein_names_refseq": "phosphogluconate dehydrogenase (decarboxylating) GND2", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR256W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;17322287;24374639;9133741;9169869", "class_list": "", "function": "Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VV36", "ec_number_list": [ { "id": "1.1.1.44", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.44", "type": "external" } ], "go_molecular_function": "GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0009051 pentose-phosphate shunt, oxidative branch;GO:0019521 D-gluconate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P53319-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53320-1", "uniprot_id": [ { "id": "MTM1_YEAST", "url": "https://www.uniprot.org/uniprot/P53320", "type": "external" } ], "mass": 40763.0, "length": 366, "protein_name": "Mitochondrial carrier protein MTM1", "gene_name": "MTM1", "organism": "Yeast", "refseq_name": "Mtm1p", "refseq_ac": [ { "id": "NP_011773", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011773", "type": "external" } ], "gene_names_uniprotkb": "MTM1; G9175", "gene_names_refseq": "MTM1", "protein_names_uniprotkb": "Mitochondrial carrier protein MTM1; Manganese trafficking factor for mitochondrial SOD2", "protein_names_refseq": "Mtm1p", "tax_id": 559292, "disease": "neurodegenerative disease (Disease Ontology:DOID:1289)", "pathway": " (sce:YGR257C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12890866;14562106;16601688;18281282;18679056;24374639;33491328;9133741;9169869", "class_list": "", "function": "Involved in the mitochondrial activation of SOD2 by specifically facilitating insertion of the essential manganese cofactor. Has the ability to activate iron regulon in an iron-dependent manner. Responds to calorie restriction (CR) strength., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV37", "ec_number_list": [], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis;GO:1990542 mitochondrial transmembrane transport;GO:0031921 pyridoxal phosphate transport", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P53320-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53322-1", "uniprot_id": [ { "id": "TNA1_YEAST", "url": "https://www.uniprot.org/uniprot/P53322", "type": "external" } ], "mass": 60135.0, "length": 534, "protein_name": "High-affinity nicotinic acid transporter", "gene_name": "TNA1", "organism": "Yeast", "refseq_name": "Tna1p", "refseq_ac": [ { "id": "NP_011776", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011776", "type": "external" } ], "gene_names_uniprotkb": "TNA1", "gene_names_refseq": "TNA1", "protein_names_uniprotkb": "High-affinity nicotinic acid transporter; Nicotinic acid permease", "protein_names_refseq": "Tna1p", "tax_id": 559292, "disease": "neurodegenerative disease (Disease Ontology:DOID:1289); Parkinson's disease (Disease Ontology:DOID:14330); lysosomal storage disease (Disease Ontology:DOID:3211); sialuria (Disease Ontology:DOID:3659)", "pathway": " (sce:YGR260W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10869563;12872131;16847258;19684113;19779198;22218487;23749301;24374639;32597660;33481703;33491328;9090059;9169869", "class_list": "", "function": "Involved in the uptake of nicotinic acid., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV39", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0046943 carboxylic acid transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0046942 carboxylic acid transport;GO:1903222 quinolinic acid transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P53322-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53331-1", "uniprot_id": [ { "id": "REXO1_YEAST", "url": "https://www.uniprot.org/uniprot/P53331", "type": "external" } ], "mass": 62849.0, "length": 553, "protein_name": "RNA exonuclease 1", "gene_name": "RNH70", "organism": "Yeast", "refseq_name": "Rnh70p", "refseq_ac": [ { "id": "NP_011792", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011792", "type": "external" } ], "gene_names_uniprotkb": "RNH70; G9381; REX1", "gene_names_refseq": "REX1; RNA82; RNH70", "protein_names_uniprotkb": "RNA exonuclease 1; 3.1.-.-; RNase H(70)", "protein_names_refseq": "Rnh70p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR276C)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "10359084;10716935;16100378;17330950;18407956;18456844;19779198;19795423;19823750;22814378;23749301;24374639;30516470;32597660;33481703;33491328;9133740;9169869", "class_list": "", "function": "3' exoribonuclease required for 5S rRNA maturation and for the proper maturation of the 5' cistron of the tRNA-Arg3 dicistronic gene. Involved with REX2 in the maturation of the 5.8S rRNA, and with REX2 and REX3, in the 3' processing of the U5L snRNA (PubMed:10359084, PubMed:10716935, PubMed:16100378). Also involved in tRNA 3'-end maturation (PubMed:18456844)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VV53", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0008408 3'-5' exonuclease activity;GO:0004527 exonuclease activity;GO:0000175 3'-5'-RNA exonuclease activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0034476 U5 snRNA 3'-end processing;GO:0031125 rRNA 3'-end processing;GO:0042780 tRNA 3'-end processing;GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0002107 generation of mature 3'-end of 5S rRNA generated by RNA polymerase III", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P53331-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53333-1", "uniprot_id": [ { "id": "CWC22_YEAST", "url": "https://www.uniprot.org/uniprot/P53333", "type": "external" } ], "mass": 67294.0, "length": 577, "protein_name": "Pre-mRNA-splicing factor CWC22", "gene_name": "CWC22", "organism": "Yeast", "refseq_name": "U2-type spliceosomal complex subunit CWC22", "refseq_ac": [ { "id": "NP_011794", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011794", "type": "external" } ], "gene_names_uniprotkb": "CWC22", "gene_names_refseq": "CWC22", "protein_names_uniprotkb": "Pre-mRNA-splicing factor CWC22; Complexed with CEF1 protein 22", "protein_names_refseq": "U2-type spliceosomal complex subunit CWC22", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR278W)", "pathway_count": 1, "publication_count": 27, "publication_id_list": "11884590;14562095;14562106;14690591;17563356;18407956;19779198;20702584;20956557;23749301;24374639;27445306;27445308;27459055;27562955;27980089;28076345;28919079;29146870;29146871;29153833;30879786;32597660;33481703;33491328;9090054;9169869", "class_list": "", "function": "Involved in pre-mRNA splicing and associates with the spliceosome prior to catalytic steps and remains associated throughout the reaction (PubMed:20956557). Pre-mRNA splicing is carried out by the spliceosome, a highly dynamic complex that undergoes significant compositional and conformational changes throughout the splicing cycle. 10 conformational states of the spliceosome are named as early complex (E), pre-spliceosome (A), precursor of the pre-catalytic spliceosome (pre-B), pre-catalytic spliceosome (B), activated spliceosome (B(act)), catalytically activated complex (B*), catalytic step I complex (C), step II catalytically activated complex (C*), post-catalytic spliceosome (P), and intron lariat spliceosome (ILS). In the early complex (E), U1 snRNP recognizes the 5' splice site of the pre-mRNA. Subsequently, U2 snRNP binds stably to the branch site region, forming the pre-spliceosome (A). The U4/U5/U6 tri-snRNP then joins to create the pre-B complex. Following several rearrangements, U1 and U4 snRNPs are released, resulting in the formation of the catalytically active spliceosome (B(act)) (PubMed:27445306, PubMed:27562955). Splicing proceeds through 2 sequential transesterification reactions, which result in the removal of the intervening RNA sequences between 2 target exons. In the branching reaction, the 2'-hydroxyl group of the branch point adenosine attacks the 5' splice site, cleaving the RNA and generating a lariat intermediate. In the exon ligation recation, the 3'-hydroxyl group of the upstream exon attacks the 3' splice site, leading to exon ligation and release of the intron lariat. These steps occur spontaneously within the B* and C* complexes, respectively. The transitions from B(act) to B*, and from C to C*, are driven by the ATPase/helicases PRP2 and PRP16, respectively (PubMed:27445306, PubMed:27445308, PubMed:27562955, PubMed:27980089, PubMed:28076345, PubMed:29146870, PubMed:29146871, PubMed:29153833, PubMed:30879786). CWC22 is required for the function of PRP2 in promoting the release of the U2 components SF3a/PRP9 and SF3b/HSH155 (PubMed:20956557)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV55", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0071013 catalytic step 2 spliceosome;GO:0005684 U2-type spliceosomal complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 2.8, "record_id": "P53333-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53338-1", "uniprot_id": [ { "id": "MAL13_YEAST", "url": "https://www.uniprot.org/uniprot/P53338", "type": "external" } ], "mass": 54325.0, "length": 473, "protein_name": "Maltose fermentation regulatory protein MAL13", "gene_name": "MAL13", "organism": "Yeast", "refseq_name": "transcription factor MAL13", "refseq_ac": [ { "id": "NP_011804", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011804", "type": "external" } ], "gene_names_uniprotkb": "MAL13; G9591; MAL1R", "gene_names_refseq": "MAL13", "protein_names_uniprotkb": "Maltose fermentation regulatory protein MAL13", "protein_names_refseq": "transcription factor MAL13", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR288W)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "24374639;9090054;9169869", "class_list": "", "function": "Regulates the coordinate transcription of structural MAL1S (maltase) and AGT1 (maltose permease) genes., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV65", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0005975 carbohydrate metabolic process;GO:0000023 maltose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P53338-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53341-1", "uniprot_id": [ { "id": "MAL12_YEAST", "url": "https://www.uniprot.org/uniprot/P53341", "type": "external" } ], "mass": 68094.0, "length": 584, "protein_name": "Alpha-glucosidase MAL12", "gene_name": "MAL12", "organism": "Yeast", "refseq_name": "alpha-glucosidase MAL12", "refseq_ac": [ { "id": "NP_011808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011808", "type": "external" } ], "gene_names_uniprotkb": "MAL12; MAL1S", "gene_names_refseq": "MAL12", "protein_names_uniprotkb": "Alpha-glucosidase MAL12; 3.2.1.20; Maltase", "protein_names_refseq": "alpha-glucosidase MAL12", "tax_id": 559292, "disease": "cystinuria (Disease Ontology:DOID:9266)", "pathway": " (sce:YGR292W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "14562106;24374639;9090054;9169869", "class_list": "glycogene;glycosylhydrolase", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV67", "ec_number_list": [], "go_molecular_function": "GO:0004558 alpha-1,4-glucosidase activity;GO:0004556 alpha-amylase activity;GO:0004574 oligo-1,6-glucosidase activity;GO:0004575 sucrose alpha-glucosidase activity;GO:0033934 glucan 1,4-alpha-maltotriohydrolase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0000025 maltose catabolic process;GO:0005987 sucrose catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P53341-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.10100", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53388-1", "uniprot_id": [ { "id": "DIP5_YEAST", "url": "https://www.uniprot.org/uniprot/P53388", "type": "external" } ], "mass": 68097.0, "length": 608, "protein_name": "Dicarboxylic amino acid permease", "gene_name": "DIP5", "organism": "Yeast", "refseq_name": "dicarboxylic amino acid permease", "refseq_ac": [ { "id": "NP_015058", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015058", "type": "external" } ], "gene_names_uniprotkb": "DIP5", "gene_names_refseq": "DIP5", "protein_names_uniprotkb": "Dicarboxylic amino acid permease", "protein_names_refseq": "dicarboxylic amino acid permease", "tax_id": 559292, "disease": "retinitis pigmentosa 68 (Disease Ontology:DOID:0110374)", "pathway": " (sce:YPL265W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "10654085;11875433;14562106;16847258;18407956;19779198;19795423;19823750;20702584;21126336;21177495;22106047;22218487;23749301;24374639;32597660;33481703;33491328;9169875", "class_list": "", "function": "Can transport glutamate, aspartate, glutamine, asparagine, serine, alanine and glycine., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 19, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3A5", "ec_number_list": [], "go_molecular_function": "GO:0015171 amino acid transmembrane transporter activity;GO:0005310 dicarboxylic acid transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0071944 cell periphery;GO:0000329 fungal-type vacuole membrane;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0006865 amino acid transport;GO:0003333 amino acid transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P53388-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53389-1", "uniprot_id": [ { "id": "HOL1_YEAST", "url": "https://www.uniprot.org/uniprot/P53389", "type": "external" } ], "mass": 65348.0, "length": 586, "protein_name": "Protein HOL1", "gene_name": "HOL1", "organism": "Yeast", "refseq_name": "Hol1p", "refseq_ac": [ { "id": "NP_014453", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014453", "type": "external" } ], "gene_names_uniprotkb": "HOL1; N3494", "gene_names_refseq": "HOL1", "protein_names_uniprotkb": "Protein HOL1", "protein_names_refseq": "Hol1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR055C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "16847258;21126336;23749301;24374639;33481703;33491328;8955402;9169873", "class_list": "", "function": "Seems to be involved in the uptake of several cations and of histidinol., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1N0", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015203 polyamine transmembrane transporter activity;GO:0015665 alcohol transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0055085 transmembrane transport;GO:0006812 monoatomic cation transport;GO:1902047 polyamine transmembrane transport;GO:0015850 organic hydroxy compound transport", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P53389-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53390-1", "uniprot_id": [ { "id": "MEP3_YEAST", "url": "https://www.uniprot.org/uniprot/P53390", "type": "external" } ], "mass": 53690.0, "length": 489, "protein_name": "Ammonium transporter MEP3", "gene_name": "MEP3", "organism": "Yeast", "refseq_name": "ammonium permease MEP3", "refseq_ac": [ { "id": "NP_015464", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015464", "type": "external" } ], "gene_names_uniprotkb": "MEP3; AMT3; P9659.14", "gene_names_refseq": "MEP3", "protein_names_uniprotkb": "Ammonium transporter MEP3", "protein_names_refseq": "ammonium permease MEP3", "tax_id": 559292, "disease": "Rh deficiency syndrome (Disease Ontology:DOID:0050641); overhydrated hereditary stomatocytosis (Disease Ontology:DOID:0111562); Rh isoimmunization (Disease Ontology:DOID:4175); hemolytic anemia (Disease Ontology:DOID:583)", "pathway": " (sce:YPR138C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11486013;14562106;16847258;17322287;24374639;9169875;9234685", "class_list": "", "function": "Transporter for ammonium (both charged and uncharged NH3 and NH4) to use as a nitrogen source. The affinity of MEP2 is about twenty times higher than that of MEP1. MEP3 has the lowest affinity., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4D6;Q6B2F5", "ec_number_list": [], "go_molecular_function": "GO:0008519 ammonium channel activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane", "go_biological_process": "GO:0072488 ammonium transmembrane transport;GO:0019740 nitrogen utilization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P53390-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53394-1", "uniprot_id": [ { "id": "SULX_YEAST", "url": "https://www.uniprot.org/uniprot/P53394", "type": "external" } ], "mass": 83384.0, "length": 754, "protein_name": "Putative sulfate transporter YPR003C", "gene_name": "LPZ3C; YP9723.03C", "organism": "Yeast", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_015328", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015328", "type": "external" } ], "gene_names_uniprotkb": "LPZ3C; YP9723.03C", "gene_names_refseq": "", "protein_names_uniprotkb": "Putative sulfate transporter YPR003C", "protein_names_refseq": "uncharacterized protein", "tax_id": 559292, "disease": "brachydactyly (Disease Ontology:DOID:0050581); atelosteogenesis (Disease Ontology:DOID:0050648); congenital secretory chloride diarrhea 1 (Disease Ontology:DOID:0060296); Pendred Syndrome (Disease Ontology:DOID:0060744); multiple epiphyseal dysplasia 4 (Disease Ontology:DOID:0070300); achondrogenesis type IB (Disease Ontology:DOID:0080055); autosomal recessive nonsyndromic deafness 4 (Disease Ontology:DOID:0110498); goiter (Disease Ontology:DOID:12176); diastrophic dysplasia (Disease Ontology:DOID:14687); osteochondrodysplasia (Disease Ontology:DOID:2256); spondylolysis (Disease Ontology:DOID:2300); systemic juvenile rheumatoid arthritis (Disease Ontology:DOID:676); gastrointestinal system disease (Disease Ontology:DOID:77)", "pathway": " (sce:YPR003C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;16847258;19779198;23749301;24374639;33481703;9169875", "class_list": "", "function": "Possible sulfate transporter., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 13, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W414", "ec_number_list": [], "go_molecular_function": "GO:0008271 secondary active sulfate transmembrane transporter activity;GO:0015116 sulfate transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P53394-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53437-1", "uniprot_id": [ { "id": "RRN9_YEAST", "url": "https://www.uniprot.org/uniprot/P53437", "type": "external" } ], "mass": 42813.0, "length": 365, "protein_name": "RNA polymerase I-specific transcription initiation factor RRN9", "gene_name": "RRN9", "organism": "Yeast", "refseq_name": "Rrn9p", "refseq_ac": [ { "id": "NP_013997", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013997", "type": "external" } ], "gene_names_uniprotkb": "RRN9; YM8156.12C", "gene_names_refseq": "RRN9", "protein_names_uniprotkb": "RNA polymerase I-specific transcription initiation factor RRN9", "protein_names_refseq": "Rrn9p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR270C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;17322287;24374639;33491328;8846924;8895657;9169872;9837969", "class_list": "", "function": "Component of the UAF (upstream activation factor) complex which interacts with the upstream element of the RNA polymerase I promoter and forms a stable preinitiation complex. Together with SPT15/TBP UAF seems to stimulate basal transcription to a fully activated level., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W096;E9P918", "ec_number_list": [], "go_molecular_function": "GO:0017025 TBP-class protein binding;GO:0001181 RNA polymerase I general transcription initiation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0000500 RNA polymerase I upstream activating factor complex", "go_biological_process": "GO:0045943 positive regulation of transcription by RNA polymerase I;GO:0042790 nucleolar large rRNA transcription by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P53437-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53438-1", "uniprot_id": [ { "id": "SOK2_YEAST", "url": "https://www.uniprot.org/uniprot/P53438", "type": "external" } ], "mass": 85643.0, "length": 785, "protein_name": "Protein SOK2", "gene_name": "SOK2", "organism": "Yeast", "refseq_name": "Sok2p", "refseq_ac": [ { "id": "NP_013729", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013729", "type": "external" } ], "gene_names_uniprotkb": "SOK2; YM9711.03C", "gene_names_refseq": "SOK2", "protein_names_uniprotkb": "Protein SOK2", "protein_names_refseq": "Sok2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR016C)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "11875433;14562106;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21177495;22218487;22814378;23749301;24374639;30516470;32597660;33229814;33481703;33491328;8524252;9169872", "class_list": "", "function": "Plays a general regulatory role in the cyclic AMP-dependent protein kinase-stimulated (PKA) signal transduction pathway by regulating the expression of genes important in growth and development. May inhibit the switch from unicellular to filamentous growth., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 24, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 24, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 24, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 31, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 24, "binding_glycan_count": 0, "secondary_ac_list": "D6VZJ0", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007124 pseudohyphal growth", "synthesized_glycan_count": 0, "hit_score": 4.7, "record_id": "P53438-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53628-1", "uniprot_id": [ { "id": "SNF12_YEAST", "url": "https://www.uniprot.org/uniprot/P53628", "type": "external" } ], "mass": 63871.0, "length": 566, "protein_name": "Transcription regulatory protein SNF12", "gene_name": "SNF12", "organism": "Yeast", "refseq_name": "Snf12p", "refseq_ac": [ { "id": "NP_014420", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014420", "type": "external" } ], "gene_names_uniprotkb": "SNF12; N3224; SWP73", "gene_names_refseq": "SNF12; SWP73", "protein_names_uniprotkb": "Transcription regulatory protein SNF12; SWI/SNF complex component SWP73", "protein_names_refseq": "Snf12p", "tax_id": 559292, "disease": "Coffin-Siris syndrome 11 (Disease Ontology:DOID:0112372); familial hyperlipidemia (Disease Ontology:DOID:1168); alcohol use disorder (Disease Ontology:DOID:1574); Coffin-Siris syndrome (Disease Ontology:DOID:1925)", "pathway": " (sce:YNR023W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12524530;16204215;22031224;23749301;24374639;33229814;33491328;33502312;8804308;9169873", "class_list": "", "function": "Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 6, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 6, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 6, "total_c_glycosites": 0, 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"0000000.0000111.100000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53629-1", "uniprot_id": [ { "id": "ARE2_YEAST", "url": "https://www.uniprot.org/uniprot/P53629", "type": "external" } ], "mass": 74023.0, "length": 642, "protein_name": "Sterol O-acyltransferase 2", "gene_name": "ARE2", "organism": "Yeast", "refseq_name": "sterol acyltransferase", "refseq_ac": [ { "id": "NP_014416", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014416", "type": "external" } ], "gene_names_uniprotkb": "ARE2; N3206; SAT1", "gene_names_refseq": "ARE2; SAT1", "protein_names_uniprotkb": "Sterol O-acyltransferase 2; 2.3.1.-; Sterol-ester synthase 2", "protein_names_refseq": "sterol acyltransferase", "tax_id": 559292, "disease": "nephrotic syndrome (Disease Ontology:DOID:1184); coronary artery disease (Disease Ontology:DOID:3393); hepatocellular carcinoma (Disease Ontology:DOID:684); end stage renal disease (Disease Ontology:DOID:783); chronic kidney disease (Disease Ontology:DOID:784)", "pathway": " (sce:YNR019W)", "pathway_count": 1, "publication_count": 25, "publication_id_list": "10672016;14562106;17287358;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;21177495;22218487;22814378;23749301;24374639;24909858;28270554;31208443;32597660;33481703;33491328;8650549;8798656;9169873", "class_list": "", "function": "Sterol O-acyltransferase that catalyzes the formation of stery esters., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1J4;Q12673", "ec_number_list": [ { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" } ], "go_molecular_function": "GO:0034737 ergosterol O-acyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0008204 ergosterol metabolic process", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "P53629-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53630-1", "uniprot_id": [ { "id": "BIOD_YEAST", "url": "https://www.uniprot.org/uniprot/P53630", "type": "external" } ], "mass": 26257.0, "length": 237, "protein_name": "Dethiobiotin synthetase", "gene_name": "BIO4", "organism": "Yeast", "refseq_name": "dethiobiotin synthase", "refseq_ac": [ { "id": "NP_014455", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014455", "type": "external" } ], "gene_names_uniprotkb": "BIO4; N3506", "gene_names_refseq": "BIO4", "protein_names_uniprotkb": "Dethiobiotin synthetase; 6.3.3.3; DTB synthetase; DTBS; Dethiobiotin synthase", "protein_names_refseq": "dethiobiotin synthase", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR057C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10333520;17322287;24374639;9169873", "class_list": "", "function": "Dethiobiotin synthetase involved in the biotin biosynthesis pathway., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1N2", "ec_number_list": [ { "id": "6.3.3.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.3.3", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0004141 dethiobiotin synthase activity", "go_cellular_component": "", "go_biological_process": "GO:0009102 biotin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P53630-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53631-1", "uniprot_id": [ { "id": "HXT17_YEAST", "url": "https://www.uniprot.org/uniprot/P53631", "type": "external" } ], "mass": 62828.0, "length": 564, "protein_name": "Hexose transporter HXT17", "gene_name": "HXT17", "organism": "Yeast", "refseq_name": "hexose transporter HXT17", "refseq_ac": [ { "id": "NP_014470", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014470", "type": "external" } ], "gene_names_uniprotkb": "HXT17; N3615", "gene_names_refseq": "HLT4; HXT17", "protein_names_uniprotkb": "Hexose transporter HXT17", "protein_names_refseq": "hexose transporter HXT17", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR072W)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "24374639;9169873", "class_list": "", "function": "Probable glucose transporter., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1P7", "ec_number_list": [], "go_molecular_function": "GO:0005353 fructose transmembrane transporter activity;GO:0015578 mannose transmembrane transporter activity;GO:0005351 carbohydrate:proton symporter activity;GO:0055056 D-glucose transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0015797 mannitol transmembrane transport;GO:0008643 carbohydrate transport;GO:0008645 hexose transmembrane transport;GO:0015795 sorbitol transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P53631-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53718-1", "uniprot_id": [ { "id": "NRM1_YEAST", "url": "https://www.uniprot.org/uniprot/P53718", "type": "external" } ], "mass": 27564.0, "length": 249, "protein_name": "Transcription factor NRM1", "gene_name": "NRM1", "organism": "Yeast", "refseq_name": "Nrm1p", "refseq_ac": [ { "id": "NP_014406", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014406", "type": "external" } ], "gene_names_uniprotkb": "NRM1; N2044", "gene_names_refseq": "NRM1", "protein_names_uniprotkb": "Transcription factor NRM1; Negative regulator of MBF targets 1", "protein_names_refseq": "Nrm1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR009W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "14562095;14562106;16916637;17287358;17322287;18407956;22333915;24374639;30516470;32597660;33481703;33491328;7900425;9169873", "class_list": "", "function": "Negative regulatory component of the MBF complex involved in cell-cycle-dependent transcription., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, 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DNA-templated transcription;GO:0000082 G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P53718-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53723-1", "uniprot_id": [ { "id": "YN8B_YEAST", "url": "https://www.uniprot.org/uniprot/P53723", "type": "external" } ], "mass": 47093.0, "length": 404, "protein_name": "UPF0674 endoplasmic reticulum membrane protein YNR021W", "gene_name": "N3216", "organism": "Yeast", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_014418", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014418", "type": "external" } ], "gene_names_uniprotkb": "N3216", "gene_names_refseq": "", "protein_names_uniprotkb": "UPF0674 endoplasmic reticulum membrane protein YNR021W", "protein_names_refseq": "uncharacterized protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR021W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562095;14562106;22814378;24374639;9169873", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6W1J6", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0032469 endoplasmic reticulum calcium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P53723-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53724-1", "uniprot_id": [ { "id": "RM50_YEAST", "url": "https://www.uniprot.org/uniprot/P53724", "type": "external" } ], "mass": 16283.0, "length": 139, "protein_name": "Large ribosomal subunit protein bL9m", "gene_name": "MRPL50", "organism": "Yeast", "refseq_name": "mitochondrial 54S ribosomal protein bL9m MRPL50", "refseq_ac": [ { "id": "NP_014419", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014419", "type": "external" } ], "gene_names_uniprotkb": "MRPL50; N3220", "gene_names_refseq": "MRPL50; bL9m", "protein_names_uniprotkb": "Large ribosomal subunit protein bL9m; 54S ribosomal protein L50, mitochondrial", "protein_names_refseq": "mitochondrial 54S ribosomal protein bL9m MRPL50", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR022C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12392552;14562095;16823961;24374639;24675956;25609543;9169873", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1J7", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P53724-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53727-1", "uniprot_id": [ { "id": "BUD17_YEAST", "url": "https://www.uniprot.org/uniprot/P53727", "type": "external" } ], "mass": 35367.0, "length": 317, "protein_name": "Putative pyridoxal kinase BUD17", "gene_name": "BUD17", "organism": "Yeast", "refseq_name": "putative pyridoxal kinase BUD17", "refseq_ac": [ { "id": "NP_014424", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014424", "type": "external" } ], "gene_names_uniprotkb": "BUD17; N3250", "gene_names_refseq": "BUD17", "protein_names_uniprotkb": "Putative pyridoxal kinase BUD17; 2.7.1.35; Bud site selection protein 17", "protein_names_refseq": "putative pyridoxal kinase BUD17", "tax_id": 559292, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (sce:YNR027W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11452010;14562095;14562106;17322287;24374639;33491328;9169873", "class_list": "", "function": "Required for synthesis of pyridoxal-5-phosphate from vitamin B6 (By similarity). Important for bud site selection., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1K1;Q6B1Y4", "ec_number_list": [ { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008478 pyridoxal kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0009443 pyridoxal 5'-phosphate salvage;GO:0042823 pyridoxal phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P53727-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53728-1", "uniprot_id": [ { "id": "CYP8_YEAST", "url": "https://www.uniprot.org/uniprot/P53728", "type": "external" } ], "mass": 34946.0, "length": 308, "protein_name": "Peptidyl-prolyl cis-trans isomerase CYP8", "gene_name": "CPR8", "organism": "Yeast", "refseq_name": "peptidylprolyl isomerase family protein CPR8", "refseq_ac": [ { "id": "NP_014425", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014425", "type": "external" } ], "gene_names_uniprotkb": "CPR8; N3255", "gene_names_refseq": "CPR8", "protein_names_uniprotkb": "Peptidyl-prolyl cis-trans isomerase CYP8; 5.2.1.8; PPIase CYP8; Rotamase CYP8", "protein_names_refseq": "peptidylprolyl isomerase family protein CPR8", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR028W)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "17322287;24374639;9169873", "class_list": "", "function": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1K2;E9P900", "ec_number_list": [ { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0016018 cyclosporin A binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P53728-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53729-1", "uniprot_id": [ { "id": "ZNG1_YEAST", "url": "https://www.uniprot.org/uniprot/P53729", "type": "external" } ], "mass": 48122.0, "length": 429, "protein_name": "Zinc-regulated GTPase metalloprotein activator 1", "gene_name": "ZNG1", "organism": "Yeast", "refseq_name": "GTP-dependent zinc transferase", "refseq_ac": [ { "id": "NP_014426", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014426", "type": "external" } ], "gene_names_uniprotkb": "ZNG1; N3260", "gene_names_refseq": "ZNG1", "protein_names_uniprotkb": "Zinc-regulated GTPase metalloprotein activator 1; 3.6.5.-", "protein_names_refseq": "GTP-dependent zinc transferase", "tax_id": 559292, "disease": "congenital anomalies of the kidney and urinary tract (Disease Ontology:DOID:0080205)", "pathway": " (sce:YNR029C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;18407956;23749301;24374639;33491328;35584675;9169873", "class_list": "", "function": "Zinc chaperone that directly transfers zinc cofactor to target metalloproteins, thereby activating them (PubMed:35584675). Catalyzes zinc insertion into the active site of methionine aminopeptidase MAP1, which function to cleave the initiator methionine from polypeptides during or after protein translation (PubMed:35584675). Mechanistically, the N-terminal psi-PxLVp motif binds to the C6H2-type zinc finger of inactive form of MAP1 (PubMed:35584675). After formation of the docked complex, zinc is transferred from the CXCC motif in the GTPase domain of ZNG1 to the zinc binding site in the peptidase domain of MAP1 in a process requiring GTP hydrolysis (PubMed:35584675). GTP/GDP exchange is required for release of active MAP1 (PubMed:35584675)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1K3", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0008047 enzyme activator activity;GO:0008270 zinc ion binding;GO:0140827 zinc chaperone activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0051604 protein maturation;GO:0034224 cellular response to zinc ion starvation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P53729-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53730-1", "uniprot_id": [ { "id": "ALG12_YEAST", "url": "https://www.uniprot.org/uniprot/P53730", "type": "external" } ], "mass": 62672.0, "length": 551, "protein_name": "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "gene_name": "ALG12", "organism": "Yeast", "refseq_name": "dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase", "refseq_ac": [ { "id": "NP_014427", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014427", "type": "external" } ], "gene_names_uniprotkb": "ALG12; ECM39; N3265", "gene_names_refseq": "ALG12; ECM39", "protein_names_uniprotkb": "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase; 2.4.1.260; Asparagine-linked glycosylation protein 12; Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase; Extracellular mutant protein 39; Mannosyltransferase ALG12", "protein_names_refseq": "dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase", "tax_id": 559292, "disease": "congenital disorder of glycosylation type I (Disease Ontology:DOID:0050570); congenital disorder of glycosylation Ig (Disease Ontology:DOID:0080559)", "pathway": " (sce:YNR030W); (R-SCE-446193)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "10336995;14562095;14562106;15987956;16847258;17322287;24374639;9169873", "class_list": "glycogene;glycosyltransferase", "function": "Mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the eighth mannose residue in an alpha-1,6 linkage onto Man(7)GlcNAc(2)-PP-dolichol to produce Man(8)GlcNAc(2)-PP-dolichol., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1K4", "ec_number_list": [ { "id": "2.4.1.260", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.260", "type": "external" } ], "go_molecular_function": "GO:0000009 alpha-1,6-mannosyltransferase activity;GO:0052917 dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0006488 dolichol-linked oligosaccharide biosynthetic process;GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P53730-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53732-1", "uniprot_id": [ { "id": "RT12_YEAST", "url": "https://www.uniprot.org/uniprot/P53732", "type": "external" } ], "mass": 16917.0, "length": 153, "protein_name": "Small ribosomal subunit protein uS12m", "gene_name": "MRPS12", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein uS12m MRPS12", "refseq_ac": [ { "id": "NP_014434", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014434", "type": "external" } ], "gene_names_uniprotkb": "MRPS12; N3298", "gene_names_refseq": "MRPS12; uS12m", "protein_names_uniprotkb": "Small ribosomal subunit protein uS12m; 37S ribosomal protein S12, mitochondrial", "protein_names_refseq": "mitochondrial 37S ribosomal protein uS12m MRPS12", "tax_id": 559292, "disease": "sensorineural hearing loss (Disease Ontology:DOID:10003); dilated cardiomyopathy (Disease Ontology:DOID:12930); epilepsy (Disease Ontology:DOID:1826); mitochondrial metabolism disease (Disease Ontology:DOID:700)", "pathway": " (sce:YNR036C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11780787;14562106;16823961;17322287;24374639;25609543;28154081;9169873", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane (PubMed:25609543, PubMed:28154081). uS12m is required for respiratory growth (PubMed:11780787)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1L2", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005840 ribosome", "go_biological_process": "GO:0006412 translation;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P53732-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53733-1", "uniprot_id": [ { "id": "RT19_YEAST", "url": "https://www.uniprot.org/uniprot/P53733", "type": "external" } ], "mass": 10275.0, "length": 91, "protein_name": "Small ribosomal subunit protein uS19m", "gene_name": "RSM19", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein uS19m RSM19", "refseq_ac": [ { "id": "NP_014435", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014435", "type": "external" } ], "gene_names_uniprotkb": "RSM19; N3300", "gene_names_refseq": "RSM19; uS19m", "protein_names_uniprotkb": "Small ribosomal subunit protein uS19m; 37S ribosomal protein S19, mitochondrial", "protein_names_refseq": "mitochondrial 37S ribosomal protein uS19m RSM19", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR037C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11278769;12392552;14576278;24374639;25609543;28154081;9169873", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1L3", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P53733-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53744-1", "uniprot_id": [ { "id": "BIO5_YEAST", "url": "https://www.uniprot.org/uniprot/P53744", "type": "external" } ], "mass": 62428.0, "length": 561, "protein_name": "7-keto 8-aminopelargonic acid transporter", "gene_name": "BIO5", "organism": "Yeast", "refseq_name": "Bio5p", "refseq_ac": [ { "id": "NP_014454", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014454", "type": "external" } ], "gene_names_uniprotkb": "BIO5; N3502", "gene_names_refseq": "BIO5", "protein_names_uniprotkb": "7-keto 8-aminopelargonic acid transporter; KAPA transporter", "protein_names_refseq": "Bio5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR056C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10333520;16847258;24374639;9169873", "class_list": "", "function": "Transport into the cell of 7-keto 8-aminopelargonic acid., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1N1", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015185 gamma-aminobutyric acid transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0051180 vitamin transport;GO:0015812 gamma-aminobutyric acid transport;GO:0009102 biotin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P53744-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53819-1", "uniprot_id": [ { "id": "YRF16_YEAST", "url": "https://www.uniprot.org/uniprot/P53819", "type": "external" } ], "mass": 211099.0, "length": 1859, "protein_name": "Y' element ATP-dependent helicase protein 1 copy 6", "gene_name": "YRF1-6", "organism": "Yeast", "refseq_name": "Y' element ATP-dependent helicase protein 1 copy 6", "refseq_ac": [ { "id": "NP_014060", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014060", "type": "external" } ], "gene_names_uniprotkb": "YRF1-6; N0152", "gene_names_refseq": "YRF1-6; YRF1", "protein_names_uniprotkb": "Y' element ATP-dependent helicase protein 1 copy 6; 5.6.2.-", "protein_names_refseq": "Y' element ATP-dependent helicase protein 1 copy 6", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL339C)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "24374639;9169873;9837911", "class_list": "", "function": "Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0L0;O94144", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003676 nucleic acid binding;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000722 telomere maintenance via recombination", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P53819-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53823-1", "uniprot_id": [ { "id": "SNO2_YEAST", "url": "https://www.uniprot.org/uniprot/P53823", "type": "external" } ], "mass": 25208.0, "length": 222, "protein_name": "Probable pyridoxal 5'-phosphate synthase subunit SNO2", "gene_name": "SNO2", "organism": "Yeast", "refseq_name": "putative pyridoxal 5'-phosphate synthase", "refseq_ac": [ { "id": "NP_014065", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014065", "type": "external" } ], "gene_names_uniprotkb": "SNO2; N0285", "gene_names_refseq": "SNO2", "protein_names_uniprotkb": "Probable pyridoxal 5'-phosphate synthase subunit SNO2; 3.5.1.2; 4.3.3.6; PDX2 homolog 2; Pdx2.2; Pyridoxal 5'-phosphate synthase glutaminase subunit", "protein_names_refseq": "putative pyridoxal 5'-phosphate synthase", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL334C)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12271461;24374639;9169873", "class_list": "", "function": "Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of a SNZ isoform., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0L3", "ec_number_list": [ { "id": "6.3.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.5.5", "type": "external" }, { "id": "6.3.4.16", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.16", "type": "external" }, { "id": "2.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.3.2", "type": "external" }, { "id": "3.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.2", "type": "external" }, { "id": "4.3.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:4.3.2.10", "type": "external" }, { "id": "4.3.3.6", "url": "https://www.rhea-db.org/rhea/?query=ec:4.3.3.6", "type": "external" } ], "go_molecular_function": "GO:0004359 glutaminase activity;GO:0036381 pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity", "go_cellular_component": "GO:0005829 cytosol;GO:1903600 glutaminase complex", "go_biological_process": "GO:0042823 pyridoxal phosphate biosynthetic process;GO:0008614 pyridoxine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P53823-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53824-1", "uniprot_id": [ { "id": "SNZ2_YEAST", "url": "https://www.uniprot.org/uniprot/P53824", "type": "external" } ], "mass": 32033.0, "length": 298, "protein_name": "Probable pyridoxal 5'-phosphate synthase subunit SNZ2", "gene_name": "SNZ2", "organism": "Yeast", "refseq_name": "pyridoxine biosynthesis protein SNZ2", "refseq_ac": [ { "id": "NP_014066", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014066", "type": "external" } ], "gene_names_uniprotkb": "SNZ2; N0290", "gene_names_refseq": "SNZ2", "protein_names_uniprotkb": "Probable pyridoxal 5'-phosphate synthase subunit SNZ2; 4.3.3.6; PDX1 homolog 2; PLP synthase subunit SNZ2; Pdx1.2", "protein_names_refseq": "pyridoxine biosynthesis protein SNZ2", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL333W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12271461;17322287;24374639;9169873", "class_list": "", "function": "Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by a SNO isoform. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0L4", "ec_number_list": [ { "id": "3.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.2", "type": "external" }, { "id": "4.3.3.6", "url": "https://www.rhea-db.org/rhea/?query=ec:4.3.3.6", "type": "external" } ], "go_molecular_function": "GO:0003922 GMP synthase (glutamine-hydrolyzing) activity;GO:0016843 amine-lyase activity;GO:0036381 pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity", "go_cellular_component": "", "go_biological_process": "GO:0006520 amino acid metabolic process;GO:0008615 pyridoxine biosynthetic process;GO:0042823 pyridoxal phosphate biosynthetic process;GO:0042819 vitamin B6 biosynthetic process;GO:0009228 thiamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P53824-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53830-1", "uniprot_id": [ { "id": "CUS2_YEAST", "url": "https://www.uniprot.org/uniprot/P53830", "type": "external" } ], "mass": 32284.0, "length": 285, "protein_name": "Cold sensitive U2 snRNA suppressor 2", "gene_name": "CUS2", "organism": "Yeast", "refseq_name": "U2 snRNP complex subunit CUS2", "refseq_ac": [ { "id": "NP_014113", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014113", "type": "external" } ], "gene_names_uniprotkb": "CUS2; N0549", "gene_names_refseq": "CUS2", "protein_names_uniprotkb": "Cold sensitive U2 snRNA suppressor 2", "protein_names_refseq": "U2 snRNP complex subunit CUS2", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL286W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10640279;11804584;14562106;17322287;17330950;18082608;21126336;24374639;33491328;9169873;9710584", "class_list": "", "function": "U2 snRNP protein which helps to refold U2 into a structure favorable for its binding to SF3b and SF3a prior to spliceosome assembly. Mediates functional interactions between U2 RNA and PRP5. Enforces ATP dependence during formation of the prespliceosome by brokering an interaction between PRP5 and the U2 snRNP that depends on correct U2 RNA structure., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0Q7;E9P8U4", "ec_number_list": [], "go_molecular_function": "GO:0030620 U2 snRNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005686 U2 snRNP;GO:0005684 U2-type spliceosomal complex", "go_biological_process": "GO:0034337 RNA folding;GO:0000398 mRNA splicing, via spliceosome;GO:1903241 U2-type prespliceosome assembly", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P53830-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53834-1", "uniprot_id": [ { "id": "HCH1_YEAST", "url": "https://www.uniprot.org/uniprot/P53834", "type": "external" } ], "mass": 17246.0, "length": 153, "protein_name": "Hsp90 co-chaperone HCH1", "gene_name": "HCH1", "organism": "Yeast", "refseq_name": "Hch1p", "refseq_ac": [ { "id": "NP_014118", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014118", "type": "external" } ], "gene_names_uniprotkb": "HCH1; N0589", "gene_names_refseq": "HCH1", "protein_names_uniprotkb": "Hsp90 co-chaperone HCH1; High-copy Hsp90 suppressor protein 1", "protein_names_refseq": "Hch1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL281W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12504007;12604615;14562095;14562106;24374639;33481703;33491328;9169873;9990037", "class_list": "", "function": "Co-chaperone that binds to the molecular chaperone HSP82 and stimulates its ATPase activity. Although not essential, it confers thermotolerance when intracellular levels of HSP82 are limiting., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0R3", "ec_number_list": [], "go_molecular_function": "GO:0051087 protein-folding chaperone binding;GO:0001671 ATPase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P53834-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53835-1", "uniprot_id": [ { "id": "PRM1_YEAST", "url": "https://www.uniprot.org/uniprot/P53835", "type": "external" } ], "mass": 73353.0, "length": 661, "protein_name": "Plasma membrane fusion protein PRM1", "gene_name": "PRM1", "organism": "Yeast", "refseq_name": "pheromone-regulated protein PRM1", "refseq_ac": [ { "id": "NP_014120", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014120", "type": "external" } ], "gene_names_uniprotkb": "PRM1; N0605", "gene_names_refseq": "PRM1", "protein_names_uniprotkb": "Plasma membrane fusion protein PRM1; Pheromone-regulated membrane protein 1", "protein_names_refseq": "pheromone-regulated protein PRM1", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL279W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "11062271;11179416;12374868;12732146;15590839;17151357;17210951;18299351;24374639;9169873", "class_list": "", "function": "Involved in cell fusion during mating by stabilizing the plasma membrane fusion event., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 14, "predicted_n_glycosites": 14, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 14, "binding_glycan_count": 0, "secondary_ac_list": "D6W0R5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0000324 fungal-type vacuole;GO:0043332 mating projection tip", "go_biological_process": "GO:0032220 plasma membrane fusion involved in cytogamy", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P53835-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53836-1", "uniprot_id": [ { "id": "CA120_YEAST", "url": "https://www.uniprot.org/uniprot/P53836", "type": "external" } ], "mass": 118280.0, "length": 1060, "protein_name": "CCR4-NOT transcriptional complex subunit CAF120", "gene_name": "CAF120", "organism": "Yeast", "refseq_name": "Caf120p", "refseq_ac": [ { "id": "NP_014121", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014121", "type": "external" } ], "gene_names_uniprotkb": "CAF120; N0610", "gene_names_refseq": "CAF120", "protein_names_uniprotkb": "CCR4-NOT transcriptional complex subunit CAF120; 120 kDa CCR4-associated factor", "protein_names_refseq": "Caf120p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL278W)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "11733989;14562095;14562106;17287358;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;23749301;24374639;24909858;32597660;33229814;33481703;33491328;9169873", "class_list": "", "function": "Acts as a component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 49, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6W0R6", "ec_number_list": [], "go_molecular_function": "GO:0004672 protein kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005935 cellular bud neck", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "P53836-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53850-1", "uniprot_id": [ { "id": "RTC4_YEAST", "url": "https://www.uniprot.org/uniprot/P53850", "type": "external" } ], "mass": 46212.0, "length": 401, "protein_name": "Restriction of telomere capping protein 4", "gene_name": "RTC4", "organism": "Yeast", "refseq_name": "Rtc4p", "refseq_ac": [ { "id": "NP_014145", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014145", "type": "external" } ], "gene_names_uniprotkb": "RTC4; N0856", "gene_names_refseq": "RTC4", "protein_names_uniprotkb": "Restriction of telomere capping protein 4", "protein_names_refseq": "Rtc4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL254C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562095;14562106;17322287;18407956;18845848;23749301;24374639;33481703;33491328;9169873;9234673", "class_list": "", "function": "May be involved in a process influencing telomere capping., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0T9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P53850-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53851-1", "uniprot_id": [ { "id": "TEX1_YEAST", "url": "https://www.uniprot.org/uniprot/P53851", "type": "external" } ], "mass": 47167.0, "length": 422, "protein_name": "Protein TEX1", "gene_name": "TEX1", "organism": "Yeast", "refseq_name": "Tex1p", "refseq_ac": [ { "id": "NP_014146", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014146", "type": "external" } ], "gene_names_uniprotkb": "TEX1; N0860", "gene_names_refseq": "TEX1", "protein_names_uniprotkb": "Protein TEX1; Trex component 1", "protein_names_refseq": "Tex1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL253W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11979277;17322287;21126336;21177495;24374639;33491328;9169873;9234673", "class_list": "", "function": "Component of the TREX complex, which operates in coupling transcription elongation to mRNA export., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0U0", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0000445 THO complex part of transcription export complex;GO:0000346 transcription export complex", "go_biological_process": "GO:0006406 mRNA export from nucleus;GO:0006368 transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P53851-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53852-1", "uniprot_id": [ { "id": "SYC_YEAST", "url": "https://www.uniprot.org/uniprot/P53852", "type": "external" } ], "mass": 87530.0, "length": 767, "protein_name": "Cysteine--tRNA ligase", "gene_name": "N0885", "organism": "Yeast", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "N0885", "gene_names_refseq": "", "protein_names_uniprotkb": "Cysteine--tRNA ligase; 6.1.1.16; CysRS; Cysteinyl-tRNA synthetase", "protein_names_refseq": "", "tax_id": 559292, "disease": "microcephaly (Disease Ontology:DOID:10907)", "pathway": " (sce:YNL247W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "14562106;17330950;17563356;18407956;19779198;19795423;19823750;21126336;23749301;24374639;30516470;32597660;33481703;33491328;9169873;9234673;9523015", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0U6", "ec_number_list": [ { "id": "6.1.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.16", "type": "external" } ], "go_molecular_function": "GO:1990825 sequence-specific mRNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004817 cysteine-tRNA ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006423 cysteinyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P53852-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53854-1", "uniprot_id": [ { "id": "CWC25_YEAST", "url": "https://www.uniprot.org/uniprot/P53854", "type": "external" } ], "mass": 20374.0, "length": 179, "protein_name": "Pre-mRNA-splicing factor CWC25", "gene_name": "CWC25", "organism": "Yeast", "refseq_name": "U2-type spliceosomal complex subunit CWC25", "refseq_ac": [ { "id": "NP_014154", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014154", "type": "external" } ], "gene_names_uniprotkb": "CWC25; N0901", "gene_names_refseq": "CWC25", "protein_names_uniprotkb": "Pre-mRNA-splicing factor CWC25; Complexed with CEF1 protein 25", "protein_names_refseq": "U2-type spliceosomal complex subunit CWC25", 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"https://www.uniprot.org/uniprot/P53857", "type": "external" } ], "mass": 47823.0, "length": 426, "protein_name": "Uncharacterized globin-like protein YNL234W", "gene_name": "N1142", "organism": "Yeast", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "NP_014165", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014165", "type": "external" } ], "gene_names_uniprotkb": "N1142", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized globin-like protein YNL234W", "protein_names_refseq": "uncharacterized protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL234W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "14562106;18407956;19795423;19823750;21126336;23749301;24374639;30516470;32597660;33481703;33491328;8896273;9169873", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, 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FAD binding;GO:0020037 heme binding;GO:0019825 oxygen binding;GO:0008941 nitric oxide dioxygenase NAD(P)H activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0071500 cellular response to nitrosative stress;GO:0046210 nitric oxide catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P53857-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53873-1", "uniprot_id": [ { "id": "SWT21_YEAST", "url": "https://www.uniprot.org/uniprot/P53873", "type": "external" } ], "mass": 40308.0, "length": 357, "protein_name": "Protein SWT21", "gene_name": "SWT21", "organism": "Yeast", "refseq_name": "Swt21p", "refseq_ac": [ { "id": "NP_014212", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014212", "type": "external" } ], "gene_names_uniprotkb": "SWT21; N1615", "gene_names_refseq": "SWT21", "protein_names_uniprotkb": "Protein SWT21; Synthetic With TGS1 protein 21", "protein_names_refseq": "Swt21p", "tax_id": 559292, "disease": "autosomal recessive dyskeratosis congenita 3 (Disease Ontology:DOID:0070019); breast cancer (Disease Ontology:DOID:1612); rectal benign neoplasm (Disease Ontology:DOID:1984); motor neuron disease (Disease Ontology:DOID:231); ovarian cancer (Disease Ontology:DOID:2394); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); head and neck squamous cell carcinoma (Disease Ontology:DOID:5520); hepatocellular carcinoma (Disease Ontology:DOID:684); glottis squamous cell carcinoma (Disease Ontology:DOID:7031); colorectal cancer (Disease Ontology:DOID:9256); nasopharynx carcinoma (Disease Ontology:DOID:9261)", "pathway": " (sce:YNL187W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": 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The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W108", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006412 translation;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P53881-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53882-1", "uniprot_id": [ { "id": "TDA7_YEAST", "url": "https://www.uniprot.org/uniprot/P53882", "type": "external" } ], "mass": 67401.0, "length": 636, "protein_name": "Topoisomerase I damage affected protein 7", "gene_name": "TDA7", "organism": "Yeast", "refseq_name": "Tda7p", "refseq_ac": [ { "id": "NP_014223", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014223", "type": "external" } ], "gene_names_uniprotkb": "TDA7; 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This cell-cycle arrest depends upon inhibition of the G protein TEM1 by the BFA1/BUB2 complex., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W118", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus", "go_biological_process": "GO:0051301 cell division;GO:0007094 mitotic spindle assembly checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P53892-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53898-1", "uniprot_id": [ { "id": "NSG2_YEAST", "url": "https://www.uniprot.org/uniprot/P53898", "type": "external" } ], "mass": 33667.0, "length": 299, "protein_name": "Protein NSG2", "gene_name": "NSG2", "organism": "Yeast", "refseq_name": "Nsg2p", "refseq_ac": [ { "id": "NP_014243", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014243", "type": "external" } ], "gene_names_uniprotkb": "NSG2; N1747", "gene_names_refseq": "NSG2", "protein_names_uniprotkb": "Protein NSG2; INSIG homolog 2", "protein_names_refseq": "Nsg2p", "tax_id": 559292, "disease": "end stage renal disease (Disease Ontology:DOID:783); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (sce:YNL156C)", "pathway_count": 1, "publication_count": 26, "publication_id_list": "11875433;14562095;14562106;15665377;16270032;16847258;17322287;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;24374639;32597660;33481703;33491328;34965436;8686380;9169873", "class_list": "", "function": "Stabilizes the HMG-CoA reductase HMG2 by preventing its HRD1-dependent degradation. Binds directly to the sterol-sensing domain (SSD)-containing transmembrane region of HMG2, promoting its folding to protect it from degradation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 20, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W127", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0071561 nucleus-vacuole junction;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0016126 sterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "P53898-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53903-1", "uniprot_id": [ { "id": "PGA2_YEAST", "url": "https://www.uniprot.org/uniprot/P53903", "type": "external" } ], "mass": 15053.0, "length": 129, "protein_name": "Processing of GAS1 and ALP protein 2", "gene_name": "PGA2", "organism": "Yeast", "refseq_name": "Pga2p", "refseq_ac": [ { "id": "NP_014250", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014250", "type": "external" } ], "gene_names_uniprotkb": "PGA2; N1774", "gene_names_refseq": "PGA2", "protein_names_uniprotkb": "Processing of GAS1 and ALP protein 2", "protein_names_refseq": "Pga2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL149C)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "14562095;14690591;16943325;17330950;18407956;19684113;19779198;19795423;19823750;20702584;21126336;23749301;24374639;33481703;33491328;8619318;8686380;9169873", "class_list": "", "function": "Involved in the processing and trafficking of GAS1 and PHO8 glycosylated proteins., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W133", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005783 endoplasmic reticulum;GO:0031965 nuclear membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P53903-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53913-1", "uniprot_id": [ { "id": "FYV6_YEAST", "url": "https://www.uniprot.org/uniprot/P53913", "type": "external" } ], "mass": 20025.0, "length": 173, "protein_name": "Protein FYV6", "gene_name": "FYV6", "organism": "Yeast", "refseq_name": "Fyv6p", "refseq_ac": [ { "id": "NP_014266", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014266", "type": "external" } ], "gene_names_uniprotkb": "FYV6; N1215; N1850", "gene_names_refseq": "FYV6", "protein_names_uniprotkb": "Protein FYV6; Function required for yeast viability protein 6", "protein_names_refseq": "Fyv6p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL133C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "12399380;12663529;14562095;14562106;16552446;17322287;22814378;24374639;33491328;8619318;9169873", "class_list": "", "function": "Involved in telomere length regulation and required for survival upon exposure to K1 killer toxin. Promotes fully efficient non-homologous end-joining (NHEJ) by a mechanism activated in postdiauxic/stationary phase., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W149", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0006303 double-strand break repair via nonhomologous end joining", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P53913-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53916-1", "uniprot_id": [ { "id": "TEP1_YEAST", "url": "https://www.uniprot.org/uniprot/P53916", "type": "external" } ], "mass": 50152.0, "length": 434, "protein_name": "Probable phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TEP1", "gene_name": "TEP1", "organism": "Yeast", "refseq_name": "putative phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase", "refseq_ac": [ { "id": "NP_014271", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014271", "type": "external" } ], "gene_names_uniprotkb": "TEP1; N1220; N1872", "gene_names_refseq": "TEP1", "protein_names_uniprotkb": "Probable phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TEP1; 3.1.3.67", "protein_names_refseq": "putative phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase", "tax_id": 559292, "disease": "disease of metabolism (Disease Ontology:DOID:0014667); Cowden syndrome 1 (Disease Ontology:DOID:0050657); fetal alcohol spectrum disorder (Disease Ontology:DOID:0050696); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); ovarian serous carcinoma (Disease Ontology:DOID:0050933); autism spectrum disorder (Disease Ontology:DOID:0060041); cerebral cavernous malformation (Disease Ontology:DOID:0060669); macrocephaly-autism syndrome (Disease Ontology:DOID:0060867); intestinal pseudo-obstruction (Disease Ontology:DOID:0080072); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); retinitis pigmentosa (Disease Ontology:DOID:10584); portal hypertension (Disease Ontology:DOID:10762); urinary bladder cancer (Disease Ontology:DOID:11054); peripheral nervous system neoplasm (Disease Ontology:DOID:1192); leiomyoma (Disease Ontology:DOID:127); persistent fetal circulation syndrome (Disease Ontology:DOID:13042); biliary atresia (Disease Ontology:DOID:13608); endometrial cancer (Disease Ontology:DOID:1380); major depressive disorder (Disease Ontology:DOID:1470); breast cancer (Disease Ontology:DOID:1612); cancer (Disease Ontology:DOID:162); hyperinsulinism (Disease Ontology:DOID:2018); colon cancer (Disease Ontology:DOID:219); transient cerebral ischemia (Disease Ontology:DOID:224); ovarian cancer (Disease Ontology:DOID:2394); hemangiopericytoma (Disease Ontology:DOID:264); Epstein-Barr virus infectious disease (Disease Ontology:DOID:2938); substance-related disorder (Disease Ontology:DOID:303); high grade glioma (Disease Ontology:DOID:3070); angiomyolipoma (Disease Ontology:DOID:3314); bladder squamous cell carcinoma (Disease Ontology:DOID:3742); lung non-small cell carcinoma (Disease Ontology:DOID:3908); follicular thyroid carcinoma (Disease Ontology:DOID:3962); renal cell carcinoma (Disease Ontology:DOID:4450); familial meningioma (Disease Ontology:DOID:4586); intrahepatic cholangiocarcinoma (Disease Ontology:DOID:4928); esophageal cancer (Disease Ontology:DOID:5041); Cowden syndrome (Disease Ontology:DOID:6457); hepatocellular carcinoma (Disease Ontology:DOID:684); stomach disease (Disease Ontology:DOID:76); sporadic breast cancer (Disease Ontology:DOID:8029); in situ carcinoma (Disease Ontology:DOID:8719); intermediate coronary syndrome (Disease Ontology:DOID:8805); diabetic retinopathy (Disease Ontology:DOID:8947); cervix uteri carcinoma in situ (Disease Ontology:DOID:8991); colorectal cancer (Disease Ontology:DOID:9256); diabetes mellitus (Disease Ontology:DOID:9351); brain disease (Disease Ontology:DOID:936); acute myocardial infarction (Disease Ontology:DOID:9408); steatotic liver disease (Disease Ontology:DOID:9452); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (sce:YNL128W); (R-SCE-1660499); (R-SCE-1855204); (R-SCE-199418); (R-SCE-202424); (R-SCE-8948747); (R-SCE-8948751)", "pathway_count": 7, "publication_count": 5, "publication_id_list": "11070083;20489023;24374639;8619318;9169873", "class_list": "", "function": "May act as a phosphoinositide 3-phosphatase by regulating PtdIns(3,4,5)P3 levels., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 52, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W155", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" } ], "go_molecular_function": "GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0042995 cell projection", "go_biological_process": "GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0048870 cell motility;GO:0046856 phosphatidylinositol dephosphorylation;GO:0030476 ascospore wall assembly", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P53916-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53918-1", "uniprot_id": [ { "id": "ESBP6_YEAST", "url": "https://www.uniprot.org/uniprot/P53918", "type": "external" } ], "mass": 73802.0, "length": 673, "protein_name": "Uncharacterized transporter ESBP6", "gene_name": "ESBP6", "organism": "Yeast", "refseq_name": "Esbp6p", "refseq_ac": [ { "id": "NP_014274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014274", "type": "external" } ], "gene_names_uniprotkb": "ESBP6; MCH3; N1223; N1882", "gene_names_refseq": "ESBP6; MCH3", "protein_names_uniprotkb": "Uncharacterized transporter ESBP6", "protein_names_refseq": "Esbp6p", "tax_id": 559292, "disease": "Allan-Herndon-Dudley syndrome (Disease Ontology:DOID:0050631); familial hyperinsulinemic hypoglycemia 7 (Disease Ontology:DOID:0070214); cataract 47 (Disease Ontology:DOID:0070353); intellectual disability (Disease Ontology:DOID:1059); lymphangioleiomyomatosis (Disease Ontology:DOID:3319); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748)", "pathway": " (sce:YNL125C); (R-SCE-352230); (R-SCE-879518)", "pathway_count": 3, "publication_count": 13, "publication_id_list": "14562095;16847258;18407956;19779198;20702584;23749301;24374639;32597660;33481703;33491328;8619318;9090055;9169873", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 18, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6W158", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015293 symporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:0071944 cell periphery", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P53918-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53921-1", "uniprot_id": [ { "id": "RN35_YEAST", "url": "https://www.uniprot.org/uniprot/P53921", "type": "external" } ], "mass": 13244.0, "length": 115, "protein_name": "Large ribosomal subunit protein bL35m", "gene_name": "MRP35", "organism": "Yeast", "refseq_name": "mitochondrial 54S ribosomal protein bL35m MRP35", "refseq_ac": [ { "id": "NP_014277", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014277", "type": "external" } ], "gene_names_uniprotkb": "MRP35; N1901", "gene_names_refseq": "MRP35; bL35m", "protein_names_uniprotkb": "Large ribosomal subunit protein bL35m; 54S ribosomal protein MRP35", "protein_names_refseq": "mitochondrial 54S ribosomal protein bL35m MRP35", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL122C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;17054397;17322287;18780730;24374639;24675956;25609543;9090055;9169873", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B0KZR4;B0KZU1;B0KZY6;D6W161", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0015934 large ribosomal subunit", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P53921-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53934-1", "uniprot_id": [ { "id": "CARME_YEAST", "url": "https://www.uniprot.org/uniprot/P53934", "type": "external" } ], "mass": 45497.0, "length": 400, "protein_name": "Carnosine N-methyltransferase", "gene_name": "N2227", "organism": "Yeast", "refseq_name": "S-adenosylmethionine-dependent methyltransferase", "refseq_ac": [ { "id": "NP_014307", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014307", "type": "external" } ], "gene_names_uniprotkb": "N2227", "gene_names_refseq": "", "protein_names_uniprotkb": "Carnosine N-methyltransferase; 2.1.1.22", "protein_names_refseq": "S-adenosylmethionine-dependent methyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL092W); (R-SCE-70921)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "14562106;16273108;22814378;24374639;26001783;8771715;9169873", "class_list": "", "function": "N-methyltransferase that mediates the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Also methylates other L-histidine-containing di- and tripeptides such as Gly-Gly-His, Gly-His and homocarnosine (GABA-His)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W188;Q45TZ4", "ec_number_list": [ { "id": "2.1.1.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.22", "type": "external" } ], "go_molecular_function": "GO:0008757 S-adenosylmethionine-dependent methyltransferase activity;GO:0030735 carnosine N-methyltransferase activity", "go_cellular_component": "", "go_biological_process": "GO:0006479 protein methylation;GO:0035498 carnosine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P53934-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53937-1", "uniprot_id": [ { "id": "SWS2_YEAST", "url": "https://www.uniprot.org/uniprot/P53937", "type": "external" } ], "mass": 16089.0, "length": 143, "protein_name": "Small ribosomal subunit protein uS13m", "gene_name": "SWS2", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein uS13m SWS2", "refseq_ac": [ { "id": "NP_014318", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014318", "type": "external" } ], "gene_names_uniprotkb": "SWS2; N2322", "gene_names_refseq": "SWS2; uS13m", "protein_names_uniprotkb": "Small ribosomal subunit protein uS13m; 37S ribosomal protein SWS2, mitochondrial; Sick without securin protein 2", "protein_names_refseq": "mitochondrial 37S ribosomal protein uS13m SWS2", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL081C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10649453;14562095;14562106;16273108;24374639;25609543;28154081;8701611;9169873", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W198;Q45TY3", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005777 peroxisome;GO:0015935 small ribosomal subunit", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P53937-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53938-1", "uniprot_id": [ { "id": "EOS1_YEAST", "url": "https://www.uniprot.org/uniprot/P53938", "type": "external" } ], "mass": 41674.0, "length": 366, "protein_name": "N-glycosylation protein EOS1", "gene_name": "EOS1", "organism": "Yeast", "refseq_name": "Eos1p", "refseq_ac": [ { "id": "NP_014319", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014319", "type": "external" } ], "gene_names_uniprotkb": "EOS1; N2327", "gene_names_refseq": "EOS1", "protein_names_uniprotkb": "N-glycosylation protein EOS1; ER-localized and oxidants sensitive protein 1", "protein_names_refseq": "Eos1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL080C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10649453;14562106;16273108;16847258;17187761;19756047;19779198;21126336;24374639;33481703;8701611;9169873", "class_list": "", "function": "Involved in oxidative stress resistance and N-glycosylation., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6W199;Q45TY2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0034599 cellular response to oxidative stress;GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P53938-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53943-1", "uniprot_id": [ { "id": "AQR1_YEAST", "url": "https://www.uniprot.org/uniprot/P53943", "type": "external" } ], "mass": 65296.0, "length": 586, "protein_name": "Probable transporter AQR1", "gene_name": "AQR1", "organism": "Yeast", "refseq_name": "Aqr1p", "refseq_ac": [ { "id": "NP_014334", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014334", "type": "external" } ], "gene_names_uniprotkb": "AQR1; N2417; YNL2417W", "gene_names_refseq": "AQR1", "protein_names_uniprotkb": "Probable transporter AQR1", "protein_names_refseq": "Aqr1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL065W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "11922628;16847258;17322287;24374639;33481703;33491328;8533472;8701611;9169873", "class_list": "", "function": "Probable transporter that confers resistance to short-chain monocarboxylic acids and quinidine., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6W1B5;Q6B1F8", "ec_number_list": [], "go_molecular_function": "GO:0042910 xenobiotic transmembrane transporter activity;GO:0022857 transmembrane transporter activity;GO:0008028 monocarboxylic acid transmembrane transporter activity;GO:0015565 threonine efflux transmembrane transporter activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0055085 transmembrane transport;GO:0015718 monocarboxylic acid transport;GO:0032973 amino acid export across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P53943-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53946-1", "uniprot_id": [ { "id": "ARP5_YEAST", "url": "https://www.uniprot.org/uniprot/P53946", "type": "external" } ], "mass": 87560.0, "length": 755, "protein_name": "Actin-related protein 5", "gene_name": "ARP5", "organism": "Yeast", "refseq_name": "actin-related protein ARP5", "refseq_ac": [ { "id": "NP_014339", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014339", "type": "external" } ], "gene_names_uniprotkb": "ARP5; N2430; YNL2430C", "gene_names_refseq": "ARP5", "protein_names_uniprotkb": "Actin-related protein 5; Actin-like protein ARP5", "protein_names_refseq": "actin-related protein ARP5", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL059C)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "12887900;14562106;18407956;19779198;19795423;19823750;22106047;23749301;24374639;32597660;33481703;33491328;8533472;9169873;9290209", "class_list": "", "function": "Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 16, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1C0", "ec_number_list": [], "go_molecular_function": "GO:0030234 enzyme regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031011 Ino80 complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P53946-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53960-1", "uniprot_id": [ { "id": "YNE0_YEAST", "url": "https://www.uniprot.org/uniprot/P53960", "type": "external" } ], "mass": 50964.0, "length": 456, "protein_name": "Putative alanyl-tRNA editing protein alaX", "gene_name": "N2679", "organism": "Yeast", "refseq_name": "putative alanine--tRNA ligase", "refseq_ac": [ { "id": "NP_014358", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014358", "type": "external" } ], "gene_names_uniprotkb": "N2679", "gene_names_refseq": "", "protein_names_uniprotkb": "Putative alanyl-tRNA editing protein alaX; AlaXp-II; AlaXp; AlaX; Alanyl-tRNA deacylase alaX", "protein_names_refseq": "putative alanine--tRNA ligase", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL040W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;14663147;19779198;20010690;24374639;33481703;33491328;9169873", "class_list": "", "function": "May function in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1D9", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0002196 Ser-tRNA(Ala) deacylase activity;GO:0004812 aminoacyl-tRNA ligase activity;GO:0043905 L-seryl-tRNA(Thr) hydrolase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0106074 aminoacyl-tRNA metabolism involved in translational fidelity;GO:0006412 translation;GO:0043039 tRNA aminoacylation;GO:0006450 regulation of translational fidelity", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P53960-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53961-1", "uniprot_id": [ { "id": "GPI15_YEAST", "url": "https://www.uniprot.org/uniprot/P53961", "type": "external" } ], "mass": 26817.0, "length": 229, "protein_name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI15", "gene_name": "GPI15", "organism": "Yeast", "refseq_name": "phosphatidylinositol N-acetylglucosaminyltransferase GPI15", "refseq_ac": [ { "id": "NP_014360", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014360", "type": "external" } ], "gene_names_uniprotkb": "GPI15; N2687", "gene_names_refseq": "GPI15", "protein_names_uniprotkb": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI15; 2.4.1.198; GPI-GlcNAc transferase complex subunit GPI5; GPI-GnT subunit GPI5; PIGH homolog", "protein_names_refseq": "phosphatidylinositol N-acetylglucosaminyltransferase GPI15", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL038W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11746600;12775844;17322287;24374639;9169873", "class_list": "glycogene;glycosyltransferase", "function": "Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1E1;Q6B1G8", "ec_number_list": [ { "id": "2.4.1.198", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.198", "type": "external" } ], "go_molecular_function": "GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006506 GPI anchor biosynthetic process;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P53961-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53966-1", "uniprot_id": [ { "id": "KTR5_YEAST", "url": "https://www.uniprot.org/uniprot/P53966", "type": "external" } ], "mass": 61728.0, "length": 522, "protein_name": "Probable mannosyltransferase KTR5", "gene_name": "KTR5", "organism": "Yeast", "refseq_name": "putative mannosyltransferase", "refseq_ac": [ { "id": "NP_014369", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014369", "type": "external" } ], "gene_names_uniprotkb": "KTR5; N2755", "gene_names_refseq": "KTR5", "protein_names_uniprotkb": "Probable mannosyltransferase KTR5; 2.4.1.-", "protein_names_refseq": "putative mannosyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL029C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;19779198;23749301;24374639;9090056;9169873", "class_list": "glycogene;glycosyltransferase", "function": "Possible glycosyltransferase that transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W1F0", "ec_number_list": [], "go_molecular_function": "GO:0000026 alpha-1,2-mannosyltransferase activity;GO:0000030 mannosyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016020 membrane", "go_biological_process": "GO:0000032 cell wall mannoprotein biosynthetic process;GO:0006487 protein N-linked glycosylation;GO:0035269 protein O-linked glycosylation via mannose", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P53966-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010001.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53970-1", "uniprot_id": [ { "id": "EFM6_YEAST", "url": "https://www.uniprot.org/uniprot/P53970", "type": "external" } ], "mass": 27738.0, "length": 246, "protein_name": "Protein-lysine N-methyltransferase EFM6", "gene_name": "EFM6", "organism": "Yeast", "refseq_name": "putative protein-lysine N-methyltransferase", "refseq_ac": [ { "id": "NP_014374", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014374", "type": "external" } ], "gene_names_uniprotkb": "EFM6; N2809", "gene_names_refseq": "EFM6", "protein_names_uniprotkb": "Protein-lysine N-methyltransferase EFM6; 2.1.1.-; Elongation factor methyltransferase 6", "protein_names_refseq": "putative protein-lysine N-methyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL024C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562095;14562106;24374639;26115316;9169873", "class_list": "", "function": "S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha (TEF1 and TEF2) at 'Lys-390'., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1F5", "ec_number_list": [], "go_molecular_function": "GO:0008276 protein methyltransferase activity;GO:0008757 S-adenosylmethionine-dependent methyltransferase activity;GO:0016279 protein-lysine N-methyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P53970-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53971-1", "uniprot_id": [ { "id": "FAP1_YEAST", "url": "https://www.uniprot.org/uniprot/P53971", "type": "external" } ], "mass": 108495.0, "length": 965, "protein_name": "FKBP12-associated protein 1", "gene_name": "FAP1", "organism": "Yeast", "refseq_name": "Fap1p", "refseq_ac": [ { "id": "NP_014375", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014375", "type": "external" } ], "gene_names_uniprotkb": "FAP1; N2812", "gene_names_refseq": "FAP1", "protein_names_uniprotkb": "FKBP12-associated protein 1", "protein_names_refseq": "Fap1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL023C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10998178;14562106;18407956;19779198;24374639;33491328;9169873", "class_list": "", "function": "May play a role in transcription regulation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1F6", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0070651 nonfunctional rRNA decay;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P53971-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P53982-1", "uniprot_id": [ { "id": "IDHH_YEAST", "url": "https://www.uniprot.org/uniprot/P53982", "type": "external" } ], "mass": 47856.0, "length": 420, "protein_name": "Isocitrate dehydrogenase [NADP]", "gene_name": "IDP3", "organism": "Yeast", "refseq_name": "isocitrate dehydrogenase (NADP(+)) IDP3", "refseq_ac": [ { "id": "NP_014389", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014389", "type": "external" } ], "gene_names_uniprotkb": "IDP3; N2870", "gene_names_refseq": "IDP3", "protein_names_uniprotkb": "Isocitrate dehydrogenase [NADP]; 1.1.1.42; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase", "protein_names_refseq": "isocitrate dehydrogenase (NADP(+)) IDP3", "tax_id": 559292, "disease": "D-2-hydroxyglutaric aciduria (Disease Ontology:DOID:0050575); myelodysplastic syndrome (Disease Ontology:DOID:0050908); bone remodeling disease (Disease Ontology:DOID:0080005); D-2-hydroxyglutaric aciduria 2 (Disease Ontology:DOID:0111352); stomach cancer (Disease Ontology:DOID:10534); lung cancer (Disease Ontology:DOID:1324); cancer (Disease Ontology:DOID:162); status epilepticus (Disease Ontology:DOID:1824); glioblastoma (Disease Ontology:DOID:3068); high grade glioma (Disease Ontology:DOID:3070); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); autoimmune disease (Disease Ontology:DOID:417); intrahepatic cholangiocarcinoma (Disease Ontology:DOID:4928); hepatocellular clear cell carcinoma (Disease Ontology:DOID:5016); hepatocellular carcinoma (Disease Ontology:DOID:684); acute myeloid leukemia (Disease Ontology:DOID:9119)", "pathway": " (sce:YNL009W)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "17322287;24374639;9169873", "class_list": "", "function": "May function in the production of NADPH for fatty acid and sterol synthesis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 19, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1G8", "ec_number_list": [ { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0051287 NAD binding;GO:0004450 isocitrate dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005777 peroxisome", "go_biological_process": "GO:0006739 NADP+ metabolic process;GO:0006099 tricarboxylic acid cycle;GO:0006102 isocitrate metabolic process;GO:0006635 fatty acid beta-oxidation;GO:0006097 glyoxylate cycle", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P53982-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P54114-1", "uniprot_id": [ { "id": "ALDH3_YEAST", "url": "https://www.uniprot.org/uniprot/P54114", "type": "external" } ], "mass": 55385.0, "length": 506, "protein_name": "Aldehyde dehydrogenase [NAD(P)+] 2", "gene_name": "ALD3", "organism": "Yeast", "refseq_name": "aldehyde dehydrogenase (NAD(+)) ALD3", "refseq_ac": [ { "id": "NP_013892", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013892", "type": "external" } ], "gene_names_uniprotkb": "ALD3; ALD4; YM8520.18C", "gene_names_refseq": "ALD3", "protein_names_uniprotkb": "Aldehyde dehydrogenase [NAD(P)+] 2; 1.2.1.3", "protein_names_refseq": "aldehyde dehydrogenase (NAD(+)) ALD3", "tax_id": 559292, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); isolated microphthalmia 8 (Disease Ontology:DOID:0060841); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); alcohol-associated liver disease (Disease Ontology:DOID:0070658); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); heart disease (Disease Ontology:DOID:114); alcoholic liver cirrhosis (Disease Ontology:DOID:14018); alcohol use disorder (Disease Ontology:DOID:1574); pancreatic cancer (Disease Ontology:DOID:1793); brain infarction (Disease Ontology:DOID:3454); congenital diaphragmatic hernia (Disease Ontology:DOID:3827); liver disease (Disease Ontology:DOID:409); myocardial infarction (Disease Ontology:DOID:5844); hepatocellular carcinoma (Disease Ontology:DOID:684); type 2 diabetes mellitus (Disease Ontology:DOID:9352); diabetic neuropathy (Disease Ontology:DOID:9743); type 1 diabetes mellitus (Disease Ontology:DOID:9744); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (sce:YMR169C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10407263;12586697;14562106;21126336;24374639;33491328;9169872", "class_list": "", "function": "Cytoplasmic aldehyde dehydrogenase involved in ethanol oxidation. Involved in pantothenic acid production through the conversion of 3-aminopropanal to beta-alanine, an intermediate in pantothenic acid (vitamin B5) and coenzyme A (CoA) biosynthesis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 21, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZZ1", "ec_number_list": [ { "id": "1.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.5", "type": "external" }, { "id": "1.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.3", "type": "external" }, { "id": "1.2.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.64", "type": "external" } ], "go_molecular_function": "GO:0004029 aldehyde dehydrogenase (NAD+) activity;GO:0102244 3-aminopropanal dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0019483 beta-alanine biosynthetic process;GO:0006598 polyamine catabolic process;GO:0015940 pantothenate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P54114-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P54838-1", "uniprot_id": [ { "id": "DAK1_YEAST", "url": "https://www.uniprot.org/uniprot/P54838", "type": "external" } ], "mass": 62207.0, "length": 584, "protein_name": "Dihydroxyacetone kinase 1", "gene_name": "DAK1", "organism": "Yeast", "refseq_name": "dihydroxyacetone kinase", "refseq_ac": [ { "id": "NP_013641", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013641", "type": "external" } ], "gene_names_uniprotkb": "DAK1", "gene_names_refseq": "DAK1", "protein_names_uniprotkb": "Dihydroxyacetone kinase 1; 2.7.1.28; 2.7.1.29; DHA kinase 1; Glycerone kinase 1; Triokinase 1; Triose kinase 1", "protein_names_refseq": "dihydroxyacetone kinase", "tax_id": 559292, "disease": "", "pathway": " (sce:YML070W)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "14562106;15665377;17563356;18407956;19779198;19795423;19823750;20190278;23749301;24374639;32597660;33481703;33491328;9038161;9169872", "class_list": "", "function": "Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 21, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZA3", "ec_number_list": [ { "id": "2.7.1.28", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.28", "type": "external" }, { "id": "2.7.1.29", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.29", "type": "external" } ], "go_molecular_function": "GO:0004371 glycerone kinase activity;GO:0005524 ATP binding;GO:0050354 triokinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0019563 glycerol catabolic process;GO:0019588 anaerobic glycerol catabolic process;GO:0061610 glycerol to glycerone phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P54838-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P54839-1", "uniprot_id": [ { "id": "ERG13_YEAST", "url": "https://www.uniprot.org/uniprot/P54839", "type": "external" } ], "mass": 55014.0, "length": 491, "protein_name": "Hydroxymethylglutaryl-CoA synthase", "gene_name": "ERG13", "organism": "Yeast", "refseq_name": "hydroxymethylglutaryl-CoA synthase", "refseq_ac": [ { "id": "NP_013580", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013580", "type": "external" } ], "gene_names_uniprotkb": "ERG13; HMGS; YM4987.09C", "gene_names_refseq": "ERG13; HMGS", "protein_names_uniprotkb": "Hydroxymethylglutaryl-CoA synthase; 2.3.3.10; 3-hydroxy-3-methylglutaryl coenzyme A synthase; HMG-CoA synthase", "protein_names_refseq": "hydroxymethylglutaryl-CoA synthase", "tax_id": 559292, "disease": "HMG-CoA synthase 2 deficiency (Disease Ontology:DOID:0081168); extrahepatic cholestasis (Disease Ontology:DOID:13619); hepatocellular carcinoma (Disease Ontology:DOID:684); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YML126C); (R-SCE-77111); (R-SCE-9837999); (R-SCE-9969896)", "pathway_count": 4, "publication_count": 10, "publication_id_list": "12702274;14562106;18407956;21126336;24374639;32597660;32679672;33481703;33491328;9169872", "class_list": "", "function": "Hydroxymethylglutaryl-CoA synthase; part of the first module of ergosterol biosynthesis pathway that includes the early steps of the pathway, conserved across all eukaryotes, and which results in the formation of mevalonate from acetyl-coenzyme A (acetyl-CoA) (PubMed:12702274). ERG13 condenses acetyl-CoA with acetoacetyl-CoA to form hydroxymethylglutaryl-CoA (HMG-CoA) (PubMed:12702274). The first module starts with the action of the cytosolic acetyl-CoA acetyltransferase ERG10 that catalyzes the formation of acetoacetyl-CoA. The hydroxymethylglutaryl-CoA synthase ERG13 then condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. The rate-limiting step of the early module is the reduction to mevalonate by the 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductases HMG1 and HMG2 which are derived from a single ancestral HMGR gene by gene duplication (PubMed:32679672)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0F9", "ec_number_list": [ { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "7.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.2.2", "type": "external" }, { "id": "2.3.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.1", "type": "external" }, { "id": "4.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.2", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "4.98.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.98.1.1", "type": "external" }, { "id": "4.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.3", "type": "external" }, { "id": "1.2.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.2", "type": "external" }, { "id": "1.1.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.37", "type": "external" }, { "id": "1.2.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.1", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "2.3.1.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.41", "type": "external" }, { "id": "1.2.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.4", "type": "external" }, { "id": "1.2.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.5", "type": "external" }, { "id": "6.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.5", "type": "external" }, { "id": "2.3.3.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.10", "type": "external" } ], "go_molecular_function": "GO:0004421 hydroxymethylglutaryl-CoA synthase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006696 ergosterol biosynthetic process;GO:0006084 acetyl-CoA metabolic process;GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P54839-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P54885-1", "uniprot_id": [ { "id": "PROA_YEAST", "url": "https://www.uniprot.org/uniprot/P54885", "type": "external" } ], "mass": 49740.0, "length": 456, "protein_name": "Gamma-glutamyl phosphate reductase", "gene_name": "PRO2", "organism": "Yeast", "refseq_name": "glutamate-5-semialdehyde dehydrogenase", "refseq_ac": [ { "id": "NP_014968", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014968", "type": "external" } ], "gene_names_uniprotkb": "PRO2; O6155", "gene_names_refseq": "PRO2", "protein_names_uniprotkb": "Gamma-glutamyl phosphate reductase; 1.2.1.41; GPR; GSA dehydrogenase; Glutamate-5-semialdehyde dehydrogenase; Glutamyl-gamma-semialdehyde dehydrogenase", "protein_names_refseq": "glutamate-5-semialdehyde dehydrogenase", "tax_id": 559292, "disease": "autosomal dominant cutis laxa 3 (Disease Ontology:DOID:0070131); autosomal recessive cutis laxa type IIIA (Disease Ontology:DOID:0070132); autosomal recessive cutis laxa type III (Disease Ontology:DOID:0070143); hereditary spastic paraplegia 9A (Disease Ontology:DOID:0110824); hereditary spastic paraplegia 9B (Disease Ontology:DOID:0110825); enterocele (Disease Ontology:DOID:1283); hereditary spastic paraplegia (Disease Ontology:DOID:2476); cataract (Disease Ontology:DOID:83); amino acid metabolic disorder (Disease Ontology:DOID:9252)", "pathway": " (sce:YOR323C); (R-SCE-8964539); (R-SCE-9837999)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "14562106;17322287;22814378;24374639;33481703;33491328;8896266;9169874", "class_list": "", "function": "Catalyzes the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W321", "ec_number_list": [ { "id": "1.1.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.2.4", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "2.1.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.2.1", "type": "external" }, { "id": "1.2.1.41", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.41", "type": "external" } ], "go_molecular_function": "GO:0050661 NADP binding;GO:0004350 glutamate-5-semialdehyde dehydrogenase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0055129 L-proline biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P54885-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P54964-1", "uniprot_id": [ { "id": "ORN_YEAST", "url": "https://www.uniprot.org/uniprot/P54964", "type": "external" } ], "mass": 30870.0, "length": 269, "protein_name": "Oligoribonuclease, mitochondrial", "gene_name": "REX2", "organism": "Yeast", "refseq_name": "Rex2p", "refseq_ac": [ { "id": "NP_013160", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013160", "type": "external" } ], "gene_names_uniprotkb": "REX2; L2159; YNT20", "gene_names_refseq": "REX2; YNT20", "protein_names_uniprotkb": "Oligoribonuclease, mitochondrial; 3.1.15.-", "protein_names_refseq": "Rex2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR059C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;17322287;19795423;19823750;24374639;33491328;9169871;9933355", "class_list": "", "function": "3'-to-5' exoribonuclease specific for small oligoribonucleotides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY61;E9P909", "ec_number_list": [], "go_molecular_function": "GO:0003676 nucleic acid binding;GO:0000175 3'-5'-RNA exonuclease activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0034476 U5 snRNA 3'-end processing;GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0034475 U4 snRNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P54964-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P56508-1", "uniprot_id": [ { "id": "SNA2_YEAST", "url": "https://www.uniprot.org/uniprot/P56508", "type": "external" } ], "mass": 9180.0, "length": 79, "protein_name": "Protein SNA2", "gene_name": "SNA2", "organism": "Yeast", "refseq_name": "Sna2p", "refseq_ac": [ { "id": "NP_010814", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010814", "type": "external" } ], "gene_names_uniprotkb": "SNA2; YDR525BW", "gene_names_refseq": "SNA2", "protein_names_uniprotkb": "Protein SNA2", "protein_names_refseq": "Sna2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR525W-A)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "11566881;12524434;14562095;14562106;15665377;16847258;17322287;18407956;19684113;19779198;21126336;23749301;24374639;33481703;33491328;9169867;9588799", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTE7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005811 lipid droplet;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P56508-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P56628-1", "uniprot_id": [ { "id": "RL22B_YEAST", "url": "https://www.uniprot.org/uniprot/P56628", "type": "external" } ], "mass": 13827.0, "length": 122, "protein_name": "Large ribosomal subunit protein eL22B", "gene_name": "RPL22B", "organism": "Yeast", "refseq_name": "60S ribosomal protein eL22 RPL22B", "refseq_ac": [ { "id": "NP_116619", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_116619", "type": "external" } ], "gene_names_uniprotkb": "RPL22B; YFL034BC", "gene_names_refseq": "RPL22B; YFL035C-B", "protein_names_uniprotkb": "Large ribosomal subunit protein eL22B; 60S ribosomal protein L22-B; L1c; RP4; YL31", "protein_names_refseq": "60S ribosomal protein eL22 RPL22B", "tax_id": 559292, "disease": "", "pathway": " (sce:YFL034C-A)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;22096102;24374639;24524803;33491328;7670463;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTJ6", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P56628-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P80235-1", "uniprot_id": [ { "id": "CACM_YEAST", "url": "https://www.uniprot.org/uniprot/P80235", "type": "external" } ], "mass": 77766.0, "length": 687, "protein_name": "Putative mitochondrial carnitine O-acetyltransferase", "gene_name": "YAT1", "organism": "Yeast", "refseq_name": "carnitine O-acetyltransferase YAT1", "refseq_ac": [ { "id": "NP_009420", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009420", "type": "external" } ], "gene_names_uniprotkb": "YAT1", "gene_names_refseq": "YAT1", "protein_names_uniprotkb": "Putative mitochondrial carnitine O-acetyltransferase; 2.3.1.7", "protein_names_refseq": "carnitine O-acetyltransferase YAT1", "tax_id": 559292, "disease": "muscular disease (Disease Ontology:DOID:0080000); lipid metabolism disorder (Disease Ontology:DOID:3146); brain disease (Disease Ontology:DOID:936)", "pathway": " (sce:YAR035W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "17761666;24374639;33481703;7731988;8262985", "class_list": "", "function": "Involved in the transfer of acetyl-CoA into mitochondria. May also be involved in the metabolism of acetate and of ethanol., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPN4", "ec_number_list": [ { "id": "2.3.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.7", "type": "external" } ], "go_molecular_function": "GO:0004095 carnitine O-palmitoyltransferase activity;GO:0004092 carnitine O-acetyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0009437 carnitine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P80235-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P81451-1", "uniprot_id": [ { "id": "ATP19_YEAST", "url": "https://www.uniprot.org/uniprot/P81451", "type": "external" } ], "mass": 7534.0, "length": 68, "protein_name": "ATP synthase subunit K, mitochondrial", "gene_name": "ATP19", "organism": "Yeast", "refseq_name": "F1F0 ATP synthase subunit k", "refseq_ac": [ { "id": "NP_014564", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014564", "type": "external" } ], "gene_names_uniprotkb": "ATP19; YOL078BW", "gene_names_refseq": "ATP19", "protein_names_uniprotkb": "ATP synthase subunit K, mitochondrial", "protein_names_refseq": "F1F0 ATP synthase subunit k", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL077W-A)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;17322287;24374639;9169874;9178509;9857174", "class_list": "", "function": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. The K chain binds the dimeric form by interacting with the G and E chains., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1Z0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0015986 proton motive force-driven ATP synthesis;GO:1902600 proton transmembrane transport;GO:0065003 protein-containing complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P81451-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P87262-1", "uniprot_id": [ { "id": "RL34A_YEAST", "url": "https://www.uniprot.org/uniprot/P87262", "type": "external" } ], "mass": 13639.0, "length": 121, "protein_name": "Large ribosomal subunit protein eL34A", "gene_name": "RPL34A", "organism": "Yeast", "refseq_name": "60S ribosomal protein eL34 RPL34A", "refseq_ac": [ { "id": "NP_010977", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010977", "type": "external" } ], "gene_names_uniprotkb": "RPL34A; YER056BC", "gene_names_refseq": "RPL34A", "protein_names_uniprotkb": "Large ribosomal subunit protein eL34A; 60S ribosomal protein L34-A", "protein_names_refseq": "60S ribosomal protein eL34 RPL34A", "tax_id": 559292, "disease": "", "pathway": " (sce:YER056C-A)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562095;14562106;19779198;19795423;19823750;21109664;22096102;23749301;24374639;24524803;9169868;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLW0;Q03189", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0030687 preribosome, large subunit precursor;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0042254 ribosome biogenesis;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P87262-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P87275-1", "uniprot_id": [ { "id": "AIM11_YEAST", "url": "https://www.uniprot.org/uniprot/P87275", "type": "external" } ], "mass": 15753.0, "length": 137, "protein_name": "Altered inheritance of mitochondria protein 11", "gene_name": "AIM11", "organism": "Yeast", "refseq_name": "Aim11p", "refseq_ac": [ { "id": "NP_011019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011019", "type": "external" } ], "gene_names_uniprotkb": "AIM11; GEP8", "gene_names_refseq": "AIM11; GEP8", "protein_names_uniprotkb": "Altered inheritance of mitochondria protein 11; Genetic interactor of prohibitins 8", "protein_names_refseq": "Aim11p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER093C-A)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;19221197;19300474;24374639;9169868", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM01", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005777 peroxisome;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P87275-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P87284-1", "uniprot_id": [ { "id": "PMP3_YEAST", "url": "https://www.uniprot.org/uniprot/P87284", "type": "external" } ], "mass": 6138.0, "length": 55, "protein_name": "Plasma membrane proteolipid 3", "gene_name": "PMP3", "organism": "Yeast", "refseq_name": "Pmp3p", "refseq_ac": [ { "id": "NP_010562", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010562", "type": "external" } ], "gene_names_uniprotkb": "PMP3; SNA1", "gene_names_refseq": "PMP3; SNA1", "protein_names_uniprotkb": "Plasma membrane proteolipid 3", "protein_names_refseq": "Pmp3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR276C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10835350;17322287;24374639;9169867", "class_list": "", "function": "Plays a role in the regulation of membrane potential. Could mediate a proton leak., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSQ7", "ec_number_list": [], "go_molecular_function": "GO:0080025 phosphatidylinositol-3,5-bisphosphate binding;GO:0032266 phosphatidylinositol-3-phosphate binding;GO:0070300 phosphatidic acid binding;GO:0046625 sphingolipid binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0042391 regulation of membrane potential;GO:0006812 monoatomic cation transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P87284-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P89113-1", "uniprot_id": [ { "id": "DDR2_YEAST", "url": "https://www.uniprot.org/uniprot/P89113", "type": "external" } ], "mass": 5955.0, "length": 61, "protein_name": "Protein DDR2", "gene_name": "DDR2", "organism": "Yeast", "refseq_name": "Ddr2p", "refseq_ac": [ { "id": "NP_014589", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014589", "type": "external" } ], "gene_names_uniprotkb": "DDR2; YOL052BC; YOL053C-A", "gene_names_refseq": "DDR2; YOL053C-A", "protein_names_uniprotkb": "Protein DDR2", "protein_names_refseq": "Ddr2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL052C-A)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;24374639;8789261;8954934;9169874", "class_list": "", "function": "May play an important role in the response of cells to diverse environmental stresses., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6W215", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0034605 cellular response to heat;GO:0006974 DNA damage response;GO:0070301 cellular response to hydrogen peroxide;GO:0009267 cellular response to starvation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P89113-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P89886-1", "uniprot_id": [ { "id": "TMA20_YEAST", "url": "https://www.uniprot.org/uniprot/P89886", "type": "external" } ], "mass": 20278.0, "length": 181, "protein_name": "Translation machinery-associated protein 20", "gene_name": "TMA20", "organism": "Yeast", "refseq_name": "translation machinery-associated protein 20", "refseq_ac": [ { "id": "NP_010923", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010923", "type": "external" } ], "gene_names_uniprotkb": "TMA20", "gene_names_refseq": "TMA20", "protein_names_uniprotkb": "Translation machinery-associated protein 20", "protein_names_refseq": "translation machinery-associated protein 20", "tax_id": 559292, "disease": "immunodeficiency 118 (Disease Ontology:DOID:0061084)", "pathway": " (sce:YER007C-A)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10093218;14562095;14562106;16702403;19795423;19823750;22814378;24374639;33491328;9169868", "class_list": "", "function": "Involved in translation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLQ4", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0042254 ribosome biogenesis;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0001731 formation of translation preinitiation complex", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P89886-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q00723-1", "uniprot_id": [ { "id": "PRP38_YEAST", "url": "https://www.uniprot.org/uniprot/Q00723", "type": "external" } ], "mass": 27967.0, "length": 242, "protein_name": "Pre-mRNA-splicing factor 38", "gene_name": "PRP38", "organism": "Yeast", "refseq_name": "U4/U6-U5 snRNP complex subunit PRP38", "refseq_ac": [ { "id": "NP_011589", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011589", "type": "external" } ], "gene_names_uniprotkb": "PRP38", "gene_names_refseq": "PRP38", "protein_names_uniprotkb": "Pre-mRNA-splicing factor 38; Pre-mRNA-processing factor 38", "protein_names_refseq": "U4/U6-U5 snRNP complex subunit PRP38", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YGR075C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10377396;10449419;11804584;14562095;14562106;1508195;17322287;24374639;9169869;9582287", "class_list": "", "function": "Required for pre-mRNA splicing and maintenance of stable U6 small nuclear RNA levels. Implicated in the formation of stable and biologically active snRNP structures. As part of the U4/U6.U5 tri-snRNP particle, dispensible for spliceosome assembly, but required for conformational changes, which result in U4 snRNA release and the subsequent catalytic activation of the spliceosome., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUK7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0071011 precatalytic spliceosome;GO:0046540 U4/U6 x U5 tri-snRNP complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0000388 spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q00723-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q01163-1", "uniprot_id": [ { "id": "RT23_YEAST", "url": "https://www.uniprot.org/uniprot/Q01163", "type": "external" } ], "mass": 50867.0, "length": 450, "protein_name": "Small ribosomal subunit protein mS29", "gene_name": "RSM23", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein mS29 RSM23", "refseq_ac": [ { "id": "NP_011386", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_011386", "type": "external" } ], "gene_names_uniprotkb": "RSM23; G2856", "gene_names_refseq": "RSM23; mS29", "protein_names_uniprotkb": "Small ribosomal subunit protein mS29; 37S ribosomal protein S23, mitochondrial; DAP-3", "protein_names_refseq": "mitochondrial 37S ribosomal protein mS29 RSM23", "tax_id": 559292, "disease": "Perrault syndrome 7 (Disease Ontology:DOID:0061073)", "pathway": " (sce:YGL129C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "11017876;11278769;12392552;1315757;14562095;14562106;14576278;14690591;24374639;25609543;28154081;8686378;9169869", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane. mS29 binds GTP and is probably an active GTPase. GTP hydrolysis may be linked to subunit association (PubMed:25609543, PubMed:28154081). mS29 also has an extraribosomal function, being required for maintenance of mitochondrial DNA (PubMed:11017876)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VU19", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q01163-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q01766-1", "uniprot_id": [ { "id": "HAL1_YEAST", "url": "https://www.uniprot.org/uniprot/Q01766", "type": "external" } ], "mass": 32994.0, "length": 294, "protein_name": "Halotolerance protein HAL1", "gene_name": "HAL1", "organism": "Yeast", "refseq_name": "Hal1p", "refseq_ac": [ { "id": "NP_015330", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015330", "type": "external" } ], "gene_names_uniprotkb": "HAL1; YP9723.05C", "gene_names_refseq": "HAL1", "protein_names_uniprotkb": "Halotolerance protein HAL1", "protein_names_refseq": "Hal1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR005C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "1505513;19779198;21126336;23749301;24374639;33481703;33491328;9169875", "class_list": "", "function": "Involved in salt tolerance., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W416", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0009651 response to salt stress", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q01766-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q01802-1", "uniprot_id": [ { "id": "AATM_YEAST", "url": "https://www.uniprot.org/uniprot/Q01802", "type": "external" } ], "mass": 51795.0, "length": 451, "protein_name": "Aspartate aminotransferase, mitochondrial", "gene_name": "AAT1", "organism": "Yeast", "refseq_name": "aspartate transaminase AAT1", "refseq_ac": [ { "id": "NP_012816", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012816", "type": "external" } ], "gene_names_uniprotkb": "AAT1; YKL461", "gene_names_refseq": "AAT1", "protein_names_uniprotkb": "Aspartate aminotransferase, mitochondrial; 2.6.1.1; Transaminase A", "protein_names_refseq": "aspartate transaminase AAT1", "tax_id": 559292, "disease": "early infantile epileptic encephalopathy (Disease Ontology:DOID:0050709); developmental and epileptic encephalopathy 82 (Disease Ontology:DOID:0080715); neurodegenerative disease (Disease Ontology:DOID:1289); acute kidney failure (Disease Ontology:DOID:3021); schizophrenia (Disease Ontology:DOID:5419); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YKL106W); (R-SCE-389661); (R-SCE-8963693); (R-SCE-8964539); (R-SCE-9856872)", "pathway_count": 5, "publication_count": 8, "publication_id_list": "14562095;14562106;14576278;1482685;21126336;24374639;8109175;8196765", "class_list": "", "function": "Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXI2", "ec_number_list": [ { "id": "2.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.1", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006103 2-oxoglutarate metabolic process;GO:0006533 L-aspartate catabolic process;GO:0006536 glutamate metabolic process;GO:0006531 aspartate metabolic process;GO:1901605 alpha-amino acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q01802-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q01846-1", "uniprot_id": [ { "id": "MDM1_YEAST", "url": "https://www.uniprot.org/uniprot/Q01846", "type": "external" } ], "mass": 129981.0, "length": 1127, "protein_name": "Structural protein MDM1", "gene_name": "MDM1", "organism": "Yeast", "refseq_name": "Mdm1p", "refseq_ac": [ { "id": "NP_013603", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013603", "type": "external" } ], "gene_names_uniprotkb": "MDM1; YM8339.15C", "gene_names_refseq": "MDM1", "protein_names_uniprotkb": "Structural protein MDM1; Mitochondrial distribution and morphology protein 1", "protein_names_refseq": "Mdm1p", "tax_id": 559292, "disease": "autosomal recessive spinocerebellar ataxia 20 (Disease Ontology:DOID:0080066)", "pathway": " (sce:YML104C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "1378448;14562106;19779198;23749301;24374639;33229814;33481703;33491328;9169872", "class_list": "", "function": "Essential for mitotic growth. Mediates organelle inheritance., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6W0I0;Q04196", "ec_number_list": [], "go_molecular_function": "GO:0032266 phosphatidylinositol-3-phosphate binding;GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0071561 nucleus-vacuole junction;GO:0005737 cytoplasm;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0034727 piecemeal microautophagy of the nucleus;GO:0000001 mitochondrion inheritance;GO:1990854 vacuole-ER tethering", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q01846-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q01976-1", "uniprot_id": [ { "id": "ADPP_YEAST", "url": "https://www.uniprot.org/uniprot/Q01976", "type": "external" } ], "mass": 26087.0, "length": 231, "protein_name": "ADP-ribose pyrophosphatase", "gene_name": "YSA1", "organism": "Yeast", "refseq_name": "ADP-ribose diphosphatase", "refseq_ac": [ { "id": "NP_009669", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009669", "type": "external" } ], "gene_names_uniprotkb": "YSA1; YBR0907", "gene_names_refseq": "RMA2; YSA1", "protein_names_uniprotkb": "ADP-ribose pyrophosphatase; 3.6.1.13; ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ADPR-PPase; Adenosine diphosphoribose pyrophosphatase", "protein_names_refseq": "ADP-ribose diphosphatase", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR111C); (R-SCE-2393930)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10542272;14562106;1626431;17322287;18407956;22814378;24374639;30617019;33491328;7813418;7900426", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQB0", "ec_number_list": [ { "id": "3.6.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.13", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0047631 ADP-ribose diphosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0019693 ribose phosphate metabolic process;GO:0006753 nucleoside phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q01976-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02204-1", "uniprot_id": [ { "id": "RM13_YEAST", "url": "https://www.uniprot.org/uniprot/Q02204", "type": "external" } ], "mass": 30271.0, "length": 264, "protein_name": "Large ribosomal subunit protein mL50", "gene_name": "MRPL13", "organism": "Yeast", "refseq_name": "mitochondrial 54S ribosomal protein mL50 MRPL13", "refseq_ac": [ { "id": "NP_012931", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012931", "type": "external" } ], "gene_names_uniprotkb": "MRPL13; YK105", "gene_names_refseq": "MRPL13; YK105; mL50", "protein_names_uniprotkb": "Large ribosomal subunit protein mL50; 54S ribosomal protein L13, mitochondrial; YmL13", "protein_names_refseq": "mitochondrial 54S ribosomal protein mL50 MRPL13", "tax_id": 559292, "disease": "", "pathway": " (sce:YKR006C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "12748633;1441752;14562095;14562106;14576278;2060626;24374639;24675956;25609543;34965436;7954901;8196765;8220240", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VX72", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q02204-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02521-1", "uniprot_id": [ { "id": "SPP2_YEAST", "url": "https://www.uniprot.org/uniprot/Q02521", "type": "external" } ], "mass": 20648.0, "length": 185, "protein_name": "Pre-mRNA-splicing factor SPP2", "gene_name": "SPP2", "organism": "Yeast", "refseq_name": "spliceosome ATPase-activating subunit SPP2", "refseq_ac": [ { "id": "NP_014791", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014791", "type": "external" } ], "gene_names_uniprotkb": "SPP2", "gene_names_refseq": "SPP2", "protein_names_uniprotkb": "Pre-mRNA-splicing factor SPP2; Spliceosome maturation protein SPP2; Suppressor of PRP protein 2", "protein_names_refseq": "spliceosome ATPase-activating subunit SPP2", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR148C)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "11884590;14562095;14562106;15542821;18407956;19779198;20702584;21177495;22218487;23749301;24374639;30516470;32597660;33481703;33491328;7493316;9046089;9169874", "class_list": "", "function": "Involved in pre-mRNA splicing; specifically in the final stages of spliceosome maturation. Promotes the first step of splicing., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2K5;Q12353", "ec_number_list": [], "go_molecular_function": "GO:0003676 nucleic acid binding;GO:0001671 ATPase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005681 spliceosomal complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q02521-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02554-1", "uniprot_id": [ { "id": "CUS1_YEAST", "url": "https://www.uniprot.org/uniprot/Q02554", "type": "external" } ], "mass": 50253.0, "length": 436, "protein_name": "Cold sensitive U2 snRNA suppressor 1", "gene_name": "CUS1", "organism": "Yeast", "refseq_name": "U2 snRNP complex subunit CUS1", "refseq_ac": [ { "id": "NP_013967", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013967", "type": "external" } ], "gene_names_uniprotkb": "CUS1; YM9408.02C", "gene_names_refseq": "CUS1", "protein_names_uniprotkb": "Cold sensitive U2 snRNA suppressor 1", "protein_names_refseq": "U2 snRNP complex subunit CUS1", "tax_id": 559292, "disease": "Goldenhar syndrome (Disease Ontology:DOID:2907)", "pathway": " (sce:YMR240C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "11884590;14517302;14562106;17322287;19779198;24374639;32597660;33481703;33491328;8566755;9169872", "class_list": "", "function": "Essential splicing protein required for U2 snRNP binding to pre-mRNA during spliceosome assembly., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W066;Q04012", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0071013 catalytic step 2 spliceosome;GO:0005686 U2 snRNP;GO:0071011 precatalytic spliceosome;GO:0071004 U2-type prespliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0000245 spliceosomal complex assembly;GO:1903241 U2-type prespliceosome assembly", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q02554-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02608-1", "uniprot_id": [ { "id": "RT16_YEAST", "url": "https://www.uniprot.org/uniprot/Q02608", "type": "external" } ], "mass": 13639.0, "length": 121, "protein_name": "Small ribosomal subunit protein bS16m", "gene_name": "MRPS16", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein bS16m MRPS16", "refseq_ac": [ { "id": "NP_015312", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015312", "type": "external" } ], "gene_names_uniprotkb": "MRPS16; LPA4C", "gene_names_refseq": "MRPS16; bS16m", "protein_names_uniprotkb": "Small ribosomal subunit protein bS16m; 37S ribosomal protein S16, mitochondrial", "protein_names_refseq": "mitochondrial 37S ribosomal protein bS16m MRPS16", "tax_id": 559292, "disease": "combined oxidative phosphorylation deficiency 2 (Disease Ontology:DOID:0111483)", "pathway": " (sce:YPL013C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12392552;14562095;14576278;24374639;25609543;28154081;9169875", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3Z9", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q02608-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02648-1", "uniprot_id": [ { "id": "TRM44_YEAST", "url": "https://www.uniprot.org/uniprot/Q02648", "type": "external" } ], "mass": 64855.0, "length": 567, "protein_name": "tRNA (uracil-O(2)-)-methyltransferase", "gene_name": "TRM44", "organism": "Yeast", "refseq_name": "tRNA (uracil) methyltransferase", "refseq_ac": [ { "id": "NP_015295", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015295", "type": "external" } ], "gene_names_uniprotkb": "TRM44", "gene_names_refseq": "TRM44", "protein_names_uniprotkb": "tRNA (uracil-O(2)-)-methyltransferase; 2.1.1.211; tRNA Um(44) 2'-O-methyltransferase; tRNA(Ser) (uridine(44)-2'-O)-methyltransferase", "protein_names_refseq": "tRNA (uracil) methyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL030W)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "14562095;14562106;17330950;17563356;18025252;18407956;19779198;19795423;19823750;21177495;23749301;24374639;30516470;32053677;32597660;33481703;33491328;9169875", "class_list": "", "function": "tRNA (uracil-O(2)-)-methyltransferase, which catalyzes the formation of O(2)-methyluracil at position 44 (Um44) in tRNA(Ser)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3Y3;Q03090;Q2XN15", "ec_number_list": [ { "id": "2.1.1.211", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.211", "type": "external" } ], "go_molecular_function": "GO:0016300 tRNA (uridine) methyltransferase activity;GO:0141101 tRNA(Ser) (uridine(44)-2'-O-)-methyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0002128 tRNA nucleoside ribose methylation;GO:0030488 tRNA methylation", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q02648-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02710-1", "uniprot_id": [ { "id": "ECM23_YEAST", "url": "https://www.uniprot.org/uniprot/Q02710", "type": "external" } ], "mass": 20614.0, "length": 187, "protein_name": "Protein ECM23", "gene_name": "ECM23", "organism": "Yeast", "refseq_name": "Ecm23p", "refseq_ac": [ { "id": "NP_015304", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015304", "type": "external" } ], "gene_names_uniprotkb": "ECM23; SRD2", "gene_names_refseq": "ECM23; SRD2", "protein_names_uniprotkb": "Protein ECM23; Extracellular mutant protein 23; SRD1 homolog 2", "protein_names_refseq": "Ecm23p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL021W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11889490;17101777;24374639;33481703;9169875;9335584", "class_list": "", "function": "Involved in morphogenesis. May be involved in cell wall organization and biogenesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3Z1", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0007124 pseudohyphal growth;GO:0071555 cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q02710-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02721-1", "uniprot_id": [ { "id": "TO6BL_YEAST", "url": "https://www.uniprot.org/uniprot/Q02721", "type": "external" } ], "mass": 30237.0, "length": 264, "protein_name": "Meiotic recombination protein REC102", "gene_name": "REC102", "organism": "Yeast", "refseq_name": "Rec102p", "refseq_ac": [ { "id": "NP_013433", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013433", "type": "external" } ], "gene_names_uniprotkb": "REC102; L8543.17", "gene_names_refseq": "REC102", "protein_names_uniprotkb": "Meiotic recombination protein REC102", "protein_names_refseq": "Rec102p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR329W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10224247;11805049;12897161;15044957;1545806;15655113;17244705;17264124;1732169;17322287;17558514;2060778;24374639;26917764;39304764;9169871", "class_list": "", "function": "Required for formation of the SPO11-mediated double-strand breaks (DSBs) that initiate meiotic recombination (PubMed:10224247, PubMed:11805049, PubMed:15655113, PubMed:17264124, PubMed:1732169, PubMed:39304764). May mediate the interaction between SPO11 subunits during meiosis (PubMed:10224247, PubMed:11805049, PubMed:15655113, PubMed:17264124, PubMed:1732169, PubMed:39304764). Also needed for homolog chromosome pairing, synaptonemal complex formation, and for the proper timing of the first meiotic division (PubMed:10224247, PubMed:11805049, PubMed:15655113, PubMed:17264124, PubMed:1732169, PubMed:39304764). Not required for mitosis and mitotic DNA repair mechanisms (PubMed:10224247, PubMed:11805049, PubMed:15655113, PubMed:17264124, PubMed:1732169, PubMed:39304764)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYX1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000794 condensed nuclear chromosome", "go_biological_process": "GO:0042138 meiotic DNA double-strand break formation;GO:0007131 reciprocal meiotic recombination", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q02721-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02753-1", "uniprot_id": [ { "id": "RL21A_YEAST", "url": "https://www.uniprot.org/uniprot/Q02753", "type": "external" } ], "mass": 18242.0, "length": 160, "protein_name": "Large ribosomal subunit protein eL21A", "gene_name": "RPL21A", "organism": "Yeast", "refseq_name": "60S ribosomal protein eL21 RPL21A", "refseq_ac": [ { "id": "NP_009750", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_009750", "type": "external" } ], "gene_names_uniprotkb": "RPL21A; URP1; YBR1401", "gene_names_refseq": "RPL21A; URP1", "protein_names_uniprotkb": "Large ribosomal subunit protein eL21A; 60S ribosomal protein L21-A", "protein_names_refseq": "60S ribosomal protein eL21 RPL21A", "tax_id": 559292, "disease": "hypotrichosis 12 (Disease Ontology:DOID:0110709)", "pathway": " (sce:YBR191W); (R-SCE-156827); (R-SCE-1799339); (R-SCE-72689); (R-SCE-72706); (R-SCE-975956); (R-SCE-975957); (R-SCE-9954709); (R-SCE-9954714)", "pathway_count": 9, "publication_count": 19, "publication_id_list": "10601260;11701127;14562095;14976550;18407956;19779198;20702584;21109664;22096102;23749301;24374639;24524803;32597660;33491328;7813418;7871891;8346681;8428379;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQI5", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q02753-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02770-1", "uniprot_id": [ { "id": "CWC27_YEAST", "url": "https://www.uniprot.org/uniprot/Q02770", "type": "external" } ], "mass": 35026.0, "length": 301, "protein_name": "Peptidyl-prolyl isomerase CWC27", "gene_name": "CWC27", "organism": "Yeast", "refseq_name": "putative peptidylprolyl isomerase CWC27", "refseq_ac": [ { "id": "NP_015261", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015261", "type": "external" } ], "gene_names_uniprotkb": "CWC27; CYP7", "gene_names_refseq": "CWC27", "protein_names_uniprotkb": "Peptidyl-prolyl isomerase CWC27; 5.2.1.8; Complexed with CEF1 protein 27; PPIase CWC27; Rotamase CWC27", "protein_names_refseq": "putative peptidylprolyl isomerase CWC27", "tax_id": 559292, "disease": "retinitis pigmentosa (Disease Ontology:DOID:10584)", "pathway": " (sce:YPL064C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11884590;14562095;14562106;24374639;33491328;9169875", "class_list": "", "function": "PPIases accelerate the folding of proteins. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in pre-mRNA splicing (PubMed:11884590)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3V1", "ec_number_list": [ { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0071013 catalytic step 2 spliceosome;GO:0005684 U2-type spliceosomal complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q02770-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02772-1", "uniprot_id": [ { "id": "COA5_YEAST", "url": "https://www.uniprot.org/uniprot/Q02772", "type": "external" } ], "mass": 12394.0, "length": 108, "protein_name": "Cytochrome c oxidase assembly factor PET191", "gene_name": "PET191", "organism": "Yeast", "refseq_name": "Pet191p", "refseq_ac": [ { "id": "NP_012568", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_012568", "type": "external" } ], "gene_names_uniprotkb": "PET191; J1604", "gene_names_refseq": "PET191", "protein_names_uniprotkb": "Cytochrome c oxidase assembly factor PET191", "protein_names_refseq": "Pet191p", "tax_id": 559292, "disease": "mitochondrial complex IV deficiency nuclear type 9 (Disease Ontology:DOID:0080359)", "pathway": " (sce:YJR034W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "11914276;14576278;17322287;22984289;24374639;7668047;7957102;8381337;8641269", "class_list": "", "function": "Assembly factor for cytochrome c oxidase (respiratory chain complex IV). Stabilizes an early formation of cytochrome c oxidase assembly factors, until it is displaced by the metallochaperone copper-delivery protein COX17., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWK7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0033617 mitochondrial respiratory chain complex IV assembly", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q02772-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02796-1", "uniprot_id": [ { "id": "LGE1_YEAST", "url": "https://www.uniprot.org/uniprot/Q02796", "type": "external" } ], "mass": 37309.0, "length": 332, "protein_name": "Transcriptional regulatory protein LGE1", "gene_name": "LGE1", "organism": "Yeast", "refseq_name": "Lge1p", "refseq_ac": [ { "id": "NP_015270", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015270", "type": "external" } ], "gene_names_uniprotkb": "LGE1", "gene_names_refseq": "LGE1", "protein_names_uniprotkb": "Transcriptional regulatory protein LGE1; Large cells protein 1", "protein_names_refseq": "Lge1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL055C)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "12089449;12535538;14562095;14562106;15528187;17322287;18407956;24374639;26046779;32597660;33229814;33481703;33491328;33856219;9169875", "class_list": "", "function": "Required to activate transcription of PDR3, a gene involved in retrograde regulation of multidrug resistance, a phenomenon that takes place in cells that have lost their mitochondrial genome. Also required for ubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. Its precise role in H2BK123ub1 formation however is unclear and is independent of retrograde regulation of multidrug resistance function., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 9, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 9, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 9, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D6W3V9;Q6Q5I8", "ec_number_list": [], "go_molecular_function": "GO:0140693 molecular condensate scaffold activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0031509 subtelomeric heterochromatin formation;GO:0006351 DNA-templated transcription;GO:0008361 regulation of cell size;GO:0006279 premeiotic DNA replication", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "Q02796-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02803-1", "uniprot_id": [ { "id": "OAZ_YEAST", "url": "https://www.uniprot.org/uniprot/Q02803", "type": "external" } ], "mass": 34045.0, "length": 292, "protein_name": "Ornithine decarboxylase antizyme", "gene_name": "OAZ1", "organism": "Yeast", "refseq_name": "Oaz1p", "refseq_ac": [ { "id": "NP_015273", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015273", "type": "external" } ], "gene_names_uniprotkb": "OAZ1", "gene_names_refseq": "OAZ1; YPL052W-A", "protein_names_uniprotkb": "Ornithine decarboxylase antizyme; ODC-Az", "protein_names_refseq": "Oaz1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL052W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "15538383;17322287;18089576;21900894;24374639;33229814;9169875", "class_list": "", "function": "Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis in response to increased intracellular polyamine levels (PubMed:15538383). Binds to ODC/SPE1 monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome (PubMed:18089576)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6W3W2", "ec_number_list": [], "go_molecular_function": "GO:0008073 ornithine decarboxylase inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0061136 regulation of proteasomal protein catabolic process;GO:0075523 viral translational frameshifting;GO:2001125 negative regulation of translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q02803-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02863-1", "uniprot_id": [ { "id": "UBP16_YEAST", "url": "https://www.uniprot.org/uniprot/Q02863", "type": "external" } ], "mass": 56920.0, "length": 499, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 16", "gene_name": "UBP16", "organism": "Yeast", "refseq_name": "putative ubiquitin-specific protease UBP16", "refseq_ac": [ { "id": "NP_015253", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015253", "type": "external" } ], "gene_names_uniprotkb": "UBP16; LPF12W", "gene_names_refseq": "UBP16", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 16; 3.4.19.12; Deubiquitinating enzyme 16; Ubiquitin thioesterase 16; Ubiquitin-specific-processing protease 16", "protein_names_refseq": "putative ubiquitin-specific protease UBP16", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL072W)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "14562106;24374639;9169875", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3U3", "ec_number_list": [], "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q02863-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02866-1", "uniprot_id": [ { "id": "MUK1_YEAST", "url": "https://www.uniprot.org/uniprot/Q02866", "type": "external" } ], "mass": 69538.0, "length": 612, "protein_name": "Protein MUK1", "gene_name": "MUK1", "organism": "Yeast", "refseq_name": "guanine nucleotide exchange factor MUK1", "refseq_ac": [ { "id": "NP_015255", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015255", "type": "external" } ], "gene_names_uniprotkb": "MUK1", "gene_names_refseq": "MUK1", "protein_names_uniprotkb": "Protein MUK1", "protein_names_refseq": "guanine nucleotide exchange factor MUK1", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL070W); (R-SCE-8876198)", "pathway_count": 2, "publication_count": 18, "publication_id_list": "14562095;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;24374639;32597660;33229814;33481703;33491328;9169875", "class_list": "", "function": "Putative GTPase-activating protein., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 5, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 5, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 5, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 35, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6W3U5", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0030139 endocytic vesicle", "go_biological_process": "GO:0036010 protein localization to endosome;GO:0006895 Golgi to endosome transport;GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "Q02866-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02875-1", "uniprot_id": [ { "id": "SYH1_YEAST", "url": "https://www.uniprot.org/uniprot/Q02875", "type": "external" } ], "mass": 94357.0, "length": 849, "protein_name": "SMY2 homolog 2", "gene_name": "SYH1", "organism": "Yeast", "refseq_name": "Syh1p", "refseq_ac": [ { "id": "NP_015220", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015220", "type": "external" } ], "gene_names_uniprotkb": "SYH1", "gene_names_refseq": "MYR1; SYH1", "protein_names_uniprotkb": "SMY2 homolog 2", "protein_names_refseq": "Syh1p", "tax_id": 559292, "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037); Parkinson's disease (Disease Ontology:DOID:14330); schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (sce:YPL105C)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "14562095;14562106;15665377;16120600;16702403;17330950;17563356;18407956;19779198;20702584;21126336;22218487;23749301;24374639;24909858;30516470;32597660;33229814;33481703;33491328;9169875", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 13, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 13, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 13, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 35, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 13, "binding_glycan_count": 0, "secondary_ac_list": "D6W3R2", "ec_number_list": [], "go_molecular_function": "GO:0000900 mRNA regulatory element binding translation repressor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0045947 negative regulation of translational initiation;GO:0051664 nuclear pore localization", "synthesized_glycan_count": 0, "hit_score": 3.6, "record_id": "Q02875-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02883-1", "uniprot_id": [ { "id": "FMP30_YEAST", "url": "https://www.uniprot.org/uniprot/Q02883", "type": "external" } ], "mass": 54368.0, "length": 468, "protein_name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, mitochondrial", "gene_name": "FMP30", "organism": "Yeast", "refseq_name": "N-acetylphosphatidylethanolamine-hydrolyzing phospholipase D", "refseq_ac": [ { "id": "NP_015222", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015222", "type": "external" } ], "gene_names_uniprotkb": "FMP30", "gene_names_refseq": "FMP30", "protein_names_uniprotkb": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, mitochondrial; 3.1.4.54; Found in mitochondrial proteome protein 30; NAPE-PLD; NAPE-hydrolyzing phospholipase D", "protein_names_refseq": "N-acetylphosphatidylethanolamine-hydrolyzing phospholipase D", "tax_id": 559292, "disease": "alcohol use disorder (Disease Ontology:DOID:1574); osteoarthritis (Disease Ontology:DOID:8398); cocaine dependence (Disease Ontology:DOID:9975)", "pathway": " (sce:YPL103C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;14576278;15878693;16254148;24374639;9169875", "class_list": "", "function": "Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3R4", "ec_number_list": [ { "id": "3.1.4.54", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.54", "type": "external" } ], "go_molecular_function": "GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0070291 N-acylethanolamine metabolic process;GO:0009395 phospholipid catabolic process;GO:0070292 N-acylphosphatidylethanolamine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q02883-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02889-1", "uniprot_id": [ { "id": "MGR2_YEAST", "url": "https://www.uniprot.org/uniprot/Q02889", "type": "external" } ], "mass": 12252.0, "length": 113, "protein_name": "Protein MGR2", "gene_name": "MGR2", "organism": "Yeast", "refseq_name": "Mgr2p", "refseq_ac": [ { "id": "NP_015227", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015227", "type": "external" } ], "gene_names_uniprotkb": "MGR2", "gene_names_refseq": "MGR2", "protein_names_uniprotkb": "Protein MGR2; Mitochondrial genome-required protein 2", "protein_names_refseq": "Mgr2p", "tax_id": 559292, "disease": "ureteral obstruction (Disease Ontology:DOID:5199)", "pathway": " (sce:YPL098C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "16267274;16847258;17322287;24374639;9169875", "class_list": "", "function": "Required for cell viability in cells lacking mitochondrial DNA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3R8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005744 TIM23 mitochondrial import inner membrane translocase complex", "go_biological_process": "GO:0045039 protein insertion into mitochondrial inner membrane;GO:0030150 protein import into mitochondrial matrix", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q02889-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02891-1", "uniprot_id": [ { "id": "MCFS1_YEAST", "url": "https://www.uniprot.org/uniprot/Q02891", "type": "external" } ], "mass": 51724.0, "length": 456, "protein_name": "Medium-chain fatty acid ethyl ester synthase/esterase 1", "gene_name": "EEB1", "organism": "Yeast", "refseq_name": "medium-chain fatty acid ethyl ester synthase/esterase", "refseq_ac": [ { "id": "NP_015230", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015230", "type": "external" } ], "gene_names_uniprotkb": "EEB1; LPG13C", "gene_names_refseq": "EEB1", "protein_names_uniprotkb": "Medium-chain fatty acid ethyl ester synthase/esterase 1; 2.3.1.84; 3.1.1.-; Alcohol O-acetyltransferase; Ethyl ester biosynthesis protein 1", "protein_names_refseq": "medium-chain fatty acid ethyl ester synthase/esterase", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL095C); (R-SCE-1483191)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "14562106;16361250;17322287;24374639;33491328;9169875", "class_list": "", "function": "Displays enzymatic activity both for medium-chain fatty acid (MCFA) ethyl ester synthesis and hydrolysis (esterase activity). MCFA are toxic for yeast and this enzyme could thus be involved in their detoxification by esterification., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W3S2", "ec_number_list": [ { "id": "3.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.-", "type": "external" }, { "id": "2.3.1.84", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.84", "type": "external" }, { "id": "3.1.2.20", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.20", "type": "external" }, { "id": "3.1.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.23", "type": "external" } ], "go_molecular_function": "GO:0047372 monoacylglycerol lipase activity;GO:0008126 acetylesterase activity;GO:0034338 short-chain carboxylesterase activity;GO:0004026 alcohol O-acetyltransferase activity", "go_cellular_component": "", "go_biological_process": "GO:0051793 medium-chain fatty acid catabolic process;GO:0051792 medium-chain fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q02891-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02932-1", "uniprot_id": [ { "id": "KA120_YEAST", "url": "https://www.uniprot.org/uniprot/Q02932", "type": "external" } ], "mass": 119623.0, "length": 1032, "protein_name": "Importin beta-like protein KAP120", "gene_name": "KAP120", "organism": "Yeast", "refseq_name": "karyopherin KAP120", "refseq_ac": [ { "id": "NP_015200", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015200", "type": "external" } ], "gene_names_uniprotkb": "KAP120", "gene_names_refseq": "KAP120; LPH2", "protein_names_uniprotkb": "Importin beta-like protein KAP120; Karyopherin-120", "protein_names_refseq": "karyopherin KAP120", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL125W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10684247;11071906;12829295;14562095;14562106;16507575;16581791;22814378;24374639;9169875", "class_list": "", "function": "Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, RAN-dependent mechanism. Required for nuclear import of Ho endonuclease and RFP1, and involved in rRNA-processing and assembly or export of 60S ribosomal subunits., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3P2", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding;GO:0008139 nuclear localization sequence binding;GO:0061608 nuclear import signal receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q02932-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02959-1", "uniprot_id": [ { "id": "HOS3_YEAST", "url": "https://www.uniprot.org/uniprot/Q02959", "type": "external" } ], "mass": 79200.0, "length": 697, "protein_name": "Histone deacetylase HOS3", "gene_name": "HOS3", "organism": "Yeast", "refseq_name": "histone deacetylase", "refseq_ac": [ { "id": "NP_015209", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015209", "type": "external" } ], "gene_names_uniprotkb": "HOS3; LPH11W", "gene_names_refseq": "HOS3", "protein_names_uniprotkb": "Histone deacetylase HOS3; 3.5.1.98", "protein_names_refseq": "histone deacetylase", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL116W)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10535926;14562106;17287358;18407956;19684113;19779198;19795423;19823750;24374639;32597660;33229814;33481703;33491328;8962081;9169875", "class_list": "", "function": "Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 19, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6W3Q2", "ec_number_list": [ { "id": "3.5.1.98", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.98", "type": "external" } ], "go_molecular_function": "GO:0004407 histone deacetylase activity;GO:0141221 histone deacetylase activity, hydrolytic mechanism", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005628 prospore membrane;GO:0005935 cellular bud neck", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0000082 G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q02959-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02961-1", "uniprot_id": [ { "id": "YP113_YEAST", "url": "https://www.uniprot.org/uniprot/Q02961", "type": "external" } ], "mass": 45014.0, "length": 396, "protein_name": "Putative 2-hydroxyacid dehydrogenase YPL113C", "gene_name": "", "organism": "Yeast", "refseq_name": "glyoxylate reductase", "refseq_ac": [ { "id": "NP_015212", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015212", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Putative 2-hydroxyacid dehydrogenase YPL113C; 1.-.-.-", "protein_names_refseq": "glyoxylate reductase", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL113C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12525494;24374639;33229814;9169875", "class_list": "", "function": "Putative 2-hydroxyacid dehydrogenase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W3Q4", "ec_number_list": [], "go_molecular_function": "GO:0016618 hydroxypyruvate reductase [NAD(P)H] activity;GO:0030267 glyoxylate reductase (NADPH) activity;GO:0051287 NAD binding;GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q02961-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02969-1", "uniprot_id": [ { "id": "PEX25_YEAST", "url": "https://www.uniprot.org/uniprot/Q02969", "type": "external" } ], "mass": 44911.0, "length": 394, "protein_name": "Peroxisomal membrane protein PEX25", "gene_name": "PEX25", "organism": "Yeast", "refseq_name": "Pex25p", "refseq_ac": [ { "id": "NP_015213", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015213", "type": "external" } ], "gene_names_uniprotkb": "PEX25", "gene_names_refseq": "PEX25", "protein_names_uniprotkb": "Peroxisomal membrane protein PEX25; Peroxin-25", "protein_names_refseq": "Pex25p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL112C)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "12135984;14517321;14517338;14562095;14562106;15596542;17287358;17322287;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21441307;22218487;23749301;24374639;32597660;33481703;33491328;9169875", "class_list": "", "function": "Required for regulation of peroxisome size and maintenance. Has a role in the import of peroxisomal matrix proteins. Imports RHO1 into the peroxisome. Also promotes peroxisome division and biogenesis., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3Q5;Q6B2A9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005777 peroxisome;GO:0005778 peroxisomal membrane", "go_biological_process": "GO:0016559 peroxisome fission;GO:0007031 peroxisome organization;GO:0016558 protein import into peroxisome matrix;GO:0044375 regulation of peroxisome size", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "Q02969-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02979-1", "uniprot_id": [ { "id": "GDE1_YEAST", "url": "https://www.uniprot.org/uniprot/Q02979", "type": "external" } ], "mass": 138014.0, "length": 1223, "protein_name": "Glycerophosphocholine phosphodiesterase GDE1", "gene_name": "GDE1", "organism": "Yeast", "refseq_name": "glycerophosphocholine phosphodiesterase", "refseq_ac": [ { "id": "NP_015215", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015215", "type": "external" } ], "gene_names_uniprotkb": "GDE1", "gene_names_refseq": "GDE1", "protein_names_uniprotkb": "Glycerophosphocholine phosphodiesterase GDE1; 3.1.4.2; Glycerophosphodiester phosphodiesterase GDE1", "protein_names_refseq": "glycerophosphocholine phosphodiesterase", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL110C)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "14562095;14562106;16141200;16172116;17330950;17563356;18407956;19779198;20702584;21126336;21177495;23749301;24374639;32597660;33229814;33481703;33491328;9169875", "class_list": "", "function": "Glycerophosphocholine glycerophosphodiesterase responsible for the hydrolysis of intracellular glycerophosphocholine into glycerol-phosphate and choline (PubMed:16141200, PubMed:16172116). The choline is used for phosphatidyl-choline synthesis. Required for utilization of glycerophosphocholine as phosphate source (PubMed:16141200). May also use glycerophosphoinositol as substrate in vivo (PubMed:16172116)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W3Q7", "ec_number_list": [ { "id": "3.1.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.2", "type": "external" } ], "go_molecular_function": "GO:0047395 glycerophosphoinositol glycerophosphodiesterase activity;GO:0047389 glycerophosphocholine phosphodiesterase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0046475 glycerophospholipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "Q02979-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q02983-1", "uniprot_id": [ { "id": "RRN5_YEAST", "url": "https://www.uniprot.org/uniprot/Q02983", "type": "external" } ], "mass": 41721.0, "length": 363, "protein_name": "RNA polymerase I-specific transcription initiation factor RRN5", "gene_name": "RRN5", "organism": "Yeast", "refseq_name": "Rrn5p", "refseq_ac": [ { "id": "NP_013242", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013242", "type": "external" } ], "gene_names_uniprotkb": "RRN5; L3165; L9606.3", "gene_names_refseq": "RRN5", "protein_names_uniprotkb": "RNA polymerase I-specific transcription initiation factor RRN5", "protein_names_refseq": "Rrn5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR141W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;24374639;33491328;8846924;9169871;9837969", "class_list": "", "function": "Component of the UAF (upstream activation factor) complex which interacts with the upstream element of the RNA polymerase I promoter and forms a stable preinitiation complex. Together with SPT15/TBP UAF seems to stimulate basal transcription to a fully activated level., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYD5;Q12061", "ec_number_list": [], "go_molecular_function": "GO:0000182 rDNA binding;GO:0001181 RNA polymerase I general transcription initiation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0000500 RNA polymerase I upstream activating factor complex", "go_biological_process": "GO:0006325 chromatin organization;GO:0045943 positive regulation of transcription by RNA polymerase I;GO:0006361 transcription initiation at RNA polymerase I promoter;GO:0042790 nucleolar large rRNA transcription by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q02983-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03002-1", "uniprot_id": [ { "id": "FRK1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03002", "type": "external" } ], "mass": 97693.0, "length": 865, "protein_name": "Fatty acyl-CoA synthetase and RNA processing-associated kinase 1", "gene_name": "FRK1", "organism": "Yeast", "refseq_name": "protein kinase FRK1", "refseq_ac": [ { "id": "NP_015184", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015184", "type": "external" } ], "gene_names_uniprotkb": "FRK1", "gene_names_refseq": "FRK1", "protein_names_uniprotkb": "Fatty acyl-CoA synthetase and RNA processing-associated kinase 1; 2.7.11.1", "protein_names_refseq": "protein kinase FRK1", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL141C)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "14562095;14562106;18407956;19684113;19779198;20489023;21126336;21177495;23749301;24374639;32597660;33481703;33491328;9169875", "class_list": "", "function": "Putative serine/threonine-protein kinase that may be involved in rRNA transcription and ribosome biogenesis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 38, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3M7", "ec_number_list": [ { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "3.1.26.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.26.-", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.67", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005938 cell cortex", "go_biological_process": "GO:0000011 vacuole inheritance;GO:0045033 peroxisome inheritance", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q03002-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03016-1", "uniprot_id": [ { "id": "GIP3_YEAST", "url": "https://www.uniprot.org/uniprot/Q03016", "type": "external" } ], "mass": 140891.0, "length": 1276, "protein_name": "GLC7-interacting protein 3", "gene_name": "GIP3", "organism": "Yeast", "refseq_name": "protein phosphatase regulator GIP3", "refseq_ac": [ { "id": "NP_015188", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015188", "type": "external" } ], "gene_names_uniprotkb": "GIP3", "gene_names_refseq": "GIP3", "protein_names_uniprotkb": "GLC7-interacting protein 3", "protein_names_refseq": "protein phosphatase regulator GIP3", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL137C)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "14562095;14562106;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21177495;22218487;23749301;24374639;28270554;32597660;33229814;33481703;33491328;34965436;9169875", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 51, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6W3N1", "ec_number_list": [], "go_molecular_function": "GO:0019888 protein phosphatase regulator activity;GO:0008157 protein phosphatase 1 binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0007059 chromosome segregation", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "Q03016-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03028-1", "uniprot_id": [ { "id": "ODC1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03028", "type": "external" } ], "mass": 34206.0, "length": 310, "protein_name": "Mitochondrial 2-oxodicarboxylate carrier 1", "gene_name": "ODC1", "organism": "Yeast", "refseq_name": "mitochondrial 2-oxodicarboxylate carrier", "refseq_ac": [ { "id": "NP_015191", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015191", "type": "external" } ], "gene_names_uniprotkb": "ODC1; LPI11C", "gene_names_refseq": "ODC1", "protein_names_uniprotkb": "Mitochondrial 2-oxodicarboxylate carrier 1", "protein_names_refseq": "mitochondrial 2-oxodicarboxylate carrier", "tax_id": 559292, "disease": "mitochondrial DNA depletion syndrome 18 (Disease Ontology:DOID:0070449)", "pathway": " (sce:YPL134C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11013234;14562106;24374639;9169875", "class_list": "", "function": "Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2-oxoglutarate, adipate, glutarate, 2-oxopimelate, oxaloacetate, citrate and malate. The main physiological role is probably to supply 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol where they are used in the biosynthesis of lysine and glutamate, respectively, and in lysine catabolism., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W3N3", "ec_number_list": [], "go_molecular_function": "GO:0005471 ATP:ADP antiporter activity;GO:0005313 L-glutamate transmembrane transporter activity;GO:0015183 L-aspartate transmembrane transporter activity;GO:0005310 dicarboxylic acid transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006839 mitochondrial transport;GO:0015810 aspartate transmembrane transport;GO:0015813 L-glutamate transmembrane transport;GO:0043490 malate-aspartate shuttle;GO:0140021 mitochondrial ADP transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q03028-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03029-1", "uniprot_id": [ { "id": "SPO19_YEAST", "url": "https://www.uniprot.org/uniprot/Q03029", "type": "external" } ], "mass": 24989.0, "length": 223, "protein_name": "Sporulation-specific protein 19", "gene_name": "SPO19", "organism": "Yeast", "refseq_name": "Spo19p", "refseq_ac": [ { "id": "NP_015195", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015195", "type": "external" } ], "gene_names_uniprotkb": "SPO19", "gene_names_refseq": "SPO19", "protein_names_uniprotkb": "Sporulation-specific protein 19", "protein_names_refseq": "Spo19p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL130W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10383953;11101837;17322287;24374639;9169875", "class_list": "", "function": "Involved in sporulation. Essential for completion of the nuclear division., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3N7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005628 prospore membrane;GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0051321 meiotic cell cycle;GO:0070583 spore membrane bending pathway", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q03029-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03079-1", "uniprot_id": [ { "id": "MRX11_YEAST", "url": "https://www.uniprot.org/uniprot/Q03079", "type": "external" } ], "mass": 24166.0, "length": 207, "protein_name": "MIOREX complex component 11", "gene_name": "MRX11", "organism": "Yeast", "refseq_name": "Mrx11p", "refseq_ac": [ { "id": "NP_015284", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015284", "type": "external" } ], "gene_names_uniprotkb": "MRX11", "gene_names_refseq": "MRX11", "protein_names_uniprotkb": "MIOREX complex component 11; Mitochondrial organization of gene expression protein 11", "protein_names_refseq": "Mrx11p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL041C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "16847258;17322287;24374639;25683707;26928762;9169875", "class_list": "", "function": "Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3X2;Q6LE92", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q03079-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03085-1", "uniprot_id": [ { "id": "SRL4_YEAST", "url": "https://www.uniprot.org/uniprot/Q03085", "type": "external" } ], "mass": 31925.0, "length": 281, "protein_name": "Oxidoreductase-like protein SRL4", "gene_name": "SRL4", "organism": "Yeast", "refseq_name": "Srl4p", "refseq_ac": [ { "id": "NP_015292", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015292", "type": "external" } ], "gene_names_uniprotkb": "SRL4", "gene_names_refseq": "SRL4", "protein_names_uniprotkb": "Oxidoreductase-like protein SRL4; Suppressor of RAD53 and LCD1 4; Suppressor of RAD53 null lethality 4", "protein_names_refseq": "Srl4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL033C); (R-SCE-193144); (R-SCE-2187335); (R-SCE-5365859); (R-SCE-8964572)", "pathway_count": 5, "publication_count": 6, "publication_id_list": "10051619;17101777;18337697;19779198;24374639;9169875", "class_list": "", "function": "May be involved in the regulation of dNTP production. Induces the SOS system when expressed in E.coli, therefore, it may play a role in DNA metabolism and/or in genome stability., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3Y0", "ec_number_list": [], "go_molecular_function": "GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0009200 deoxyribonucleoside triphosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q03085-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03088-1", "uniprot_id": [ { "id": "SVL3_YEAST", "url": "https://www.uniprot.org/uniprot/Q03088", "type": "external" } ], "mass": 92144.0, "length": 825, "protein_name": "Styryl dye vacuolar localization protein 3", "gene_name": "SVL3", "organism": "Yeast", "refseq_name": "Svl3p", "refseq_ac": [ { "id": "NP_015293", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015293", "type": "external" } ], "gene_names_uniprotkb": "SVL3; P7102.17", "gene_names_refseq": "SVL3", "protein_names_uniprotkb": "Styryl dye vacuolar localization protein 3", "protein_names_refseq": "Svl3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL032C)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "14562095;14562106;15665377;17330950;17563356;18407956;19684113;19779198;20702584;21177495;22218487;23749301;24374639;30516470;32597660;33229814;33481703;33491328;9169875;9751732", "class_list": "", "function": "May have a vacuolar function., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 8, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 8, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 8, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 43, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D6W3Y1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005938 cell cortex;GO:0071944 cell periphery;GO:0005933 cellular bud;GO:0005934 cellular bud tip", "go_biological_process": "GO:0006897 endocytosis", "synthesized_glycan_count": 0, "hit_score": 3.0, "record_id": "Q03088-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03099-1", "uniprot_id": [ { "id": "YMN3_YEAST", "url": "https://www.uniprot.org/uniprot/Q03099", "type": "external" } ], "mass": 155553.0, "length": 1374, "protein_name": "Y' element ATP-dependent helicase YML133C", "gene_name": "YM4987.01C; YM4987.02C", "organism": "Yeast", "refseq_name": "Y' element ATP-dependent helicase", "refseq_ac": [ { "id": "NP_013573", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013573", "type": "external" } ], "gene_names_uniprotkb": "YM4987.01C; YM4987.02C", "gene_names_refseq": "", "protein_names_uniprotkb": "Y' element ATP-dependent helicase YML133C; 5.6.2.-", "protein_names_refseq": "Y' element ATP-dependent helicase", "tax_id": 559292, "disease": "", "pathway": " (sce:YML133C)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "24374639;9169872;9837911", "class_list": "", "function": "Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0F2;Q12054", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003676 nucleic acid binding;GO:0004386 helicase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0000722 telomere maintenance via recombination", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q03099-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03151-1", "uniprot_id": [ { "id": "MTG1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03151", "type": "external" } ], "mass": 42144.0, "length": 367, "protein_name": "Mitochondrial GTPase 1", "gene_name": "MTG1", "organism": "Yeast", "refseq_name": "putative GTPase MTG1", "refseq_ac": [ { "id": "NP_013815", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013815", "type": "external" } ], "gene_names_uniprotkb": "MTG1; YM6543.04C", "gene_names_refseq": "MTG1", "protein_names_uniprotkb": "Mitochondrial GTPase 1", "protein_names_refseq": "putative GTPase MTG1", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR097C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12808030;14562095;14562106;16823961;24374639;9169872", "class_list": "", "function": "Mitochondrial GTPase involved in assembly of the large ribosomal subunit (PubMed:12808030). Plays a role in expression of the mitochondrial translational machinery (PubMed:12808030)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZS0", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0070129 regulation of mitochondrial translation;GO:1902775 mitochondrial large ribosomal subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q03151-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03153-1", "uniprot_id": [ { "id": "ATP25_YEAST", "url": "https://www.uniprot.org/uniprot/Q03153", "type": "external" } ], "mass": 70414.0, "length": 612, "protein_name": "ATPase synthesis protein 25, mitochondrial", "gene_name": "ATP25", "organism": "Yeast", "refseq_name": "Atp25p", "refseq_ac": [ { "id": "NP_013816", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013816", "type": "external" } ], "gene_names_uniprotkb": "ATP25; YM6543.05C", "gene_names_refseq": "ATP25", "protein_names_uniprotkb": "ATPase synthesis protein 25, mitochondrial; OLI1 mRNA stabilization factor", "protein_names_refseq": "Atp25p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR098C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;14562106;16823961;18216280;24374639;9169872", "class_list": "", "function": "mRNA stabilization factor specific for the 0.95 kb OLI1 mRNA. Also involved in OLI1 ring formation., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VZS1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0048255 mRNA stabilization;GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly;GO:0140053 mitochondrial gene expression", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q03153-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03161-1", "uniprot_id": [ { "id": "YMY9_YEAST", "url": "https://www.uniprot.org/uniprot/Q03161", "type": "external" } ], "mass": 33956.0, "length": 297, "protein_name": "Glucose-6-phosphate 1-epimerase", "gene_name": "YM6543.06C", "organism": "Yeast", "refseq_name": "glucose-6-phosphate 1-epimerase", "refseq_ac": [ { "id": "NP_013817", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013817", "type": "external" } ], "gene_names_uniprotkb": "YM6543.06C", "gene_names_refseq": "", "protein_names_uniprotkb": "Glucose-6-phosphate 1-epimerase; 5.1.3.15; D-hexose-6-phosphate mutarotase", "protein_names_refseq": "glucose-6-phosphate 1-epimerase", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR099C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562106;14690591;16857670;18407956;19779198;19795423;19823750;21126336;24374639;33481703;33491328;9169872", "class_list": "", "function": "Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZS2", "ec_number_list": [ { "id": "5.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.9", "type": "external" }, { "id": "5.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.3.-", "type": "external" }, { "id": "5.1.3.15", "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.3.15", "type": "external" } ], "go_molecular_function": "GO:0030246 carbohydrate binding;GO:0047938 glucose-6-phosphate 1-epimerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0005975 carbohydrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q03161-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03175-1", "uniprot_id": [ { "id": "SRT1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03175", "type": "external" } ], "mass": 40200.0, "length": 343, "protein_name": "Dehydrodolichyl diphosphate synthase complex subunit SRT1", "gene_name": "SRT1", "organism": "Yeast", "refseq_name": "ditrans,polycis-polyprenyl diphosphate synthase", "refseq_ac": [ { "id": "NP_013819", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013819", "type": "external" } ], "gene_names_uniprotkb": "SRT1; YM6543.08C", "gene_names_refseq": "SRT1", "protein_names_uniprotkb": "Dehydrodolichyl diphosphate synthase complex subunit SRT1; 2.5.1.87; Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific)", "protein_names_refseq": "ditrans,polycis-polyprenyl diphosphate synthase", "tax_id": 559292, "disease": "developmental delay and seizures with or without movement abnormalities (Disease Ontology:DOID:0080473); retinitis pigmentosa 59 (Disease Ontology:DOID:0110352)", "pathway": " (sce:YMR101C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11442630;17345630;24374639;25066056;9169872;9858571", "class_list": "", "function": "With NUS1, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZS4", "ec_number_list": [ { "id": "2.5.1.87", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.87", "type": "external" } ], "go_molecular_function": "GO:0004659 prenyltransferase activity;GO:0045547 ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005811 lipid droplet;GO:1904423 dehydrodolichyl diphosphate synthase complex", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0043048 dolichyl monophosphate biosynthetic process;GO:0016094 polyprenol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q03175-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03201-1", "uniprot_id": [ { "id": "RT10_YEAST", "url": "https://www.uniprot.org/uniprot/Q03201", "type": "external" } ], "mass": 23424.0, "length": 203, "protein_name": "Small ribosomal subunit protein uS10m", "gene_name": "RSM10", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein uS10m RSM10", "refseq_ac": [ { "id": "NP_010326", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010326", "type": "external" } ], "gene_names_uniprotkb": "RSM10; YD6888.03", "gene_names_refseq": "RSM10; uS10m", "protein_names_uniprotkb": "Small ribosomal subunit protein uS10m; 37S ribosomal protein S10, mitochondrial", "protein_names_refseq": "mitochondrial 37S ribosomal protein uS10m RSM10", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR041W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "11278769;12392552;14562095;14562106;14576278;17322287;18407956;21126336;24374639;25609543;28154081;33481703;33491328;9169867", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS29", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0015935 small ribosomal subunit", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q03201-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03212-1", "uniprot_id": [ { "id": "EAR1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03212", "type": "external" } ], "mass": 62532.0, "length": 550, "protein_name": "Protein EAR1", "gene_name": "EAR1", "organism": "Yeast", "refseq_name": "Ear1p", "refseq_ac": [ { "id": "NP_013894", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013894", "type": "external" } ], "gene_names_uniprotkb": "EAR1; YM8010.01C; YM8520.20C", "gene_names_refseq": "EAR1", "protein_names_uniprotkb": "Protein EAR1; Endosomal adapter of RSP5", "protein_names_refseq": "Ear1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR171C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562095;14562106;18407956;19779198;21177495;23749301;24374639;32597660;33481703;33491328;9169872", "class_list": "", "function": "Components of the endosome-vacuole trafficking pathway that regulates nutrient transport. May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane (By similarity)., [UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VZZ3;Q03830", "ec_number_list": [], "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005768 endosome;GO:0005783 endoplasmic reticulum;GO:0010008 endosome membrane;GO:0005774 vacuolar membrane;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q03212-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03218-1", "uniprot_id": [ { "id": "MMT1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03218", "type": "external" } ], "mass": 56209.0, "length": 510, "protein_name": "Mitochondrial metal transporter 1", "gene_name": "MMT1", "organism": "Yeast", "refseq_name": "Mmt1p", "refseq_ac": [ { "id": "NP_013902", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013902", "type": "external" } ], "gene_names_uniprotkb": "MMT1; MFT1; YM8010.07", "gene_names_refseq": "MFT1; MMT1", "protein_names_uniprotkb": "Mitochondrial metal transporter 1", "protein_names_refseq": "Mmt1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR177W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;15107423;17322287;24374639;9169872;9353309", "class_list": "", "function": "Mitochondrial metal transporter involved in mitochondrial iron accumulation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W000;Q66R35", "ec_number_list": [], "go_molecular_function": "GO:0008324 monoatomic cation transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0016020 membrane;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis;GO:0006826 iron ion transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q03218-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03220-1", "uniprot_id": [ { "id": "CTL1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03220", "type": "external" } ], "mass": 36974.0, "length": 320, "protein_name": "Polynucleotide 5'-triphosphatase CTL1", "gene_name": "CTL1", "organism": "Yeast", "refseq_name": "polynucleotide 5'-phosphatase", "refseq_ac": [ { "id": "NP_013905", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013905", "type": "external" } ], "gene_names_uniprotkb": "CTL1; YM8010.10C", "gene_names_refseq": "CTH1; CTL1", "protein_names_uniprotkb": "Polynucleotide 5'-triphosphatase CTL1; 3.6.1.74; Capping enzyme RNA triphosphatase-like protein 1; TPase CTL1; mRNA 5'-triphosphatase CTL1", "protein_names_refseq": "polynucleotide 5'-phosphatase", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR180C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10219091;17322287;24374639;9169872", "class_list": "", "function": "Probably involved in an RNA processing event other than mRNA capping. Releases gamma-phosphate from the 5'-end of RNA to produce a diphosphate terminus., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W003", "ec_number_list": [ { "id": "3.6.1.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.74", "type": "external" } ], "go_molecular_function": "GO:0004651 polynucleotide 5'-phosphatase activity;GO:0140818 mRNA 5'-triphosphate monophosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031533 mRNA capping enzyme complex", "go_biological_process": "GO:0006370 7-methylguanosine mRNA capping", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q03220-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03246-1", "uniprot_id": [ { "id": "RT17_YEAST", "url": "https://www.uniprot.org/uniprot/Q03246", "type": "external" } ], "mass": 27635.0, "length": 237, "protein_name": "Small ribosomal subunit protein uS17m", "gene_name": "MRPS17", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein uS17m MRPS17", "refseq_ac": [ { "id": "NP_013913", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013913", "type": "external" } ], "gene_names_uniprotkb": "MRPS17; YM8010.18C", "gene_names_refseq": "MRPS17; uS17m", "protein_names_uniprotkb": "Small ribosomal subunit protein uS17m; 37S ribosomal protein S17, mitochondrial", "protein_names_refseq": "mitochondrial 37S ribosomal protein uS17m MRPS17", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR188C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12392552;14562095;14562106;14576278;15543521;24374639;25609543;28154081;7498764;9169872", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane (PubMed:25609543, PubMed:28154081). uS17m may have a meiosis-specific role as it accumulates during the middle stage of sporulation (PubMed:15543521)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W012;Q02523", "ec_number_list": [], "go_molecular_function": "GO:0019843 rRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q03246-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03254-1", "uniprot_id": [ { "id": "FCP1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03254", "type": "external" } ], "mass": 83441.0, "length": 732, "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase", "gene_name": "FCP1", "organism": "Yeast", "refseq_name": "protein serine/threonine phosphatase", "refseq_ac": [ { "id": "NP_014004", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014004", "type": "external" } ], "gene_names_uniprotkb": "FCP1; YM8021.03", "gene_names_refseq": "FCP1", "protein_names_uniprotkb": "RNA polymerase II subunit A C-terminal domain phosphatase; 3.1.3.16; CTD phosphatase FCP1", "protein_names_refseq": "protein serine/threonine phosphatase", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR277W); (R-SCE-113418); (R-SCE-674695); (R-SCE-6796648)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10445027;14562106;18407956;19779198;22106047;23749301;24374639;33481703;33491328;8798710;9169872", "class_list": "", "function": "Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1). This promotes the activity of RNA polymerase II., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0A4", "ec_number_list": [ { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "3.1.3.43", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.43", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" } ], "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q03254-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03264-1", "uniprot_id": [ { "id": "NGL2_YEAST", "url": "https://www.uniprot.org/uniprot/Q03264", "type": "external" } ], "mass": 59540.0, "length": 515, "protein_name": "RNA exonuclease NGL2", "gene_name": "NGL2", "organism": "Yeast", "refseq_name": "RNA exonuclease", "refseq_ac": [ { "id": "NP_014012", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014012", "type": "external" } ], "gene_names_uniprotkb": "NGL2; YM8021.11C", "gene_names_refseq": "NGL2", "protein_names_uniprotkb": "RNA exonuclease NGL2; 3.1.-.-; Carbon catabolite repressor protein 4 homolog", "protein_names_refseq": "RNA exonuclease", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR285C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12358428;14562106;19779198;21126336;23749301;24374639;32597660;33481703;33491328;9169872", "class_list": "", "function": "Involved in pre-rRNA processing. Required for the final stage of 3'-end maturation of 5.8S rRNA at site E., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0B2", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0004521 RNA endonuclease activity;GO:0004535 poly(A)-specific ribonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q03264-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03266-1", "uniprot_id": [ { "id": "PABC_YEAST", "url": "https://www.uniprot.org/uniprot/Q03266", "type": "external" } ], "mass": 42640.0, "length": 374, "protein_name": "Aminodeoxychorismate lyase", "gene_name": "ABZ2", "organism": "Yeast", "refseq_name": "aminodeoxychorismate lyase ABZ2", "refseq_ac": [ { "id": "NP_014016", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014016", "type": "external" } ], "gene_names_uniprotkb": "ABZ2; YM8021.15", "gene_names_refseq": "ABZ2", "protein_names_uniprotkb": "Aminodeoxychorismate lyase; 4-amino-4-deoxychorismate lyase; 4.1.3.38; ADC lyase; ADCL", "protein_names_refseq": "aminodeoxychorismate lyase ABZ2", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR289W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "14562095;14562106;24374639;9169872", "class_list": "", "function": "Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W0B6;Q03531", "ec_number_list": [ { "id": "4.1.3.38", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.3.38", "type": "external" } ], "go_molecular_function": "GO:0008696 4-amino-4-deoxychorismate lyase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0046654 tetrahydrofolate biosynthetic process;GO:0019752 carboxylic acid metabolic process;GO:0046656 folic acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q03266-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03289-1", "uniprot_id": [ { "id": "PFA5_YEAST", "url": "https://www.uniprot.org/uniprot/Q03289", "type": "external" } ], "mass": 42923.0, "length": 374, "protein_name": "Palmitoyltransferase PFA5", "gene_name": "PFA5", "organism": "Yeast", "refseq_name": "palmitoyltransferase PFA5", "refseq_ac": [ { "id": "NP_010747", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010747", "type": "external" } ], "gene_names_uniprotkb": "PFA5", "gene_names_refseq": "PFA5", "protein_names_uniprotkb": "Palmitoyltransferase PFA5; 2.3.1.225; Protein fatty acyltransferase 5", "protein_names_refseq": "palmitoyltransferase PFA5", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR459C); (R-SCE-203615)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "16186255;16847258;18407956;24374639;9169867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT83", "ec_number_list": [ { "id": "1.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.2.4", "type": "external" }, { "id": "2.3.1.225", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.225", "type": "external" } ], "go_molecular_function": "GO:0019706 protein-cysteine S-palmitoyltransferase activity;GO:0016409 palmitoyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0006612 protein targeting to membrane;GO:0018345 protein palmitoylation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q03289-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03370-1", "uniprot_id": [ { "id": "PEX29_YEAST", "url": "https://www.uniprot.org/uniprot/Q03370", "type": "external" } ], "mass": 63543.0, "length": 554, "protein_name": "Peroxisomal membrane protein PEX29", "gene_name": "PEX29", "organism": "Yeast", "refseq_name": "Pex29p", "refseq_ac": [ { "id": "NP_010767", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010767", "type": "external" } ], "gene_names_uniprotkb": "PEX29", "gene_names_refseq": "PEX29", "protein_names_uniprotkb": "Peroxisomal membrane protein PEX29; Peroxin-29", "protein_names_refseq": "Pex29p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR479C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "12707309;14562106;16847258;18407956;21126336;23749301;24374639;32597660;33481703;33491328;9169867", "class_list": "", "function": "Involved in the regulation of peroxisome number, size and distribution., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTA2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005777 peroxisome;GO:0005778 peroxisomal membrane;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0007031 peroxisome organization;GO:0032581 ER-dependent peroxisome organization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q03370-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03375-1", "uniprot_id": [ { "id": "CWC21_YEAST", "url": "https://www.uniprot.org/uniprot/Q03375", "type": "external" } ], "mass": 15763.0, "length": 135, "protein_name": "Pre-mRNA-splicing factor CWC21", "gene_name": "CWC21", "organism": "Yeast", "refseq_name": "U2-type spliceosomal complex subunit CWC21", "refseq_ac": [ { "id": "NP_010770", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010770", "type": "external" } ], "gene_names_uniprotkb": "CWC21", "gene_names_refseq": "CWC21", "protein_names_uniprotkb": "Pre-mRNA-splicing factor CWC21; Complexed with CEF1 protein 21", "protein_names_refseq": "U2-type spliceosomal complex subunit CWC21", "tax_id": 559292, "disease": "alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (sce:YDR482C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "11884590;14562095;14562106;17322287;19789211;19854871;24374639;33481703;33491328;9169867", "class_list": "", "function": "Involved in pre-mRNA splicing. May function at or prior to the first catalytic step of splicing at the catalytic center of the spliceosome, together with ISY1. May do so by stabilizing the catalytic center or the position of the RNA substrate., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTA5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005684 U2-type spliceosomal complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q03375-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03419-1", "uniprot_id": [ { "id": "IZH1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03419", "type": "external" } ], "mass": 36492.0, "length": 316, "protein_name": "ADIPOR-like receptor IZH1", "gene_name": "IZH1", "organism": "Yeast", "refseq_name": "PAQR-type receptor", "refseq_ac": [ { "id": "NP_010780", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010780", "type": "external" } ], "gene_names_uniprotkb": "IZH1", "gene_names_refseq": "IZH1", "protein_names_uniprotkb": "ADIPOR-like receptor IZH1; Implicated in zinc homeostasis protein 1", "protein_names_refseq": "PAQR-type receptor", "tax_id": 559292, "disease": "metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); alcohol-associated liver disease (Disease Ontology:DOID:0070658); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); glucose intolerance (Disease Ontology:DOID:10603); breast cancer (Disease Ontology:DOID:1612); hyperinsulinism (Disease Ontology:DOID:2018); prostate adenocarcinoma (Disease Ontology:DOID:2526); hyperglycemia (Disease Ontology:DOID:4195); macular degeneration (Disease Ontology:DOID:4448); end stage renal disease (Disease Ontology:DOID:783); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YDR492W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10884426;14562095;15060275;17322287;24374639;33491328;9169867", "class_list": "", "function": "ADIPOR-like receptor involved in zinc metabolism either by altering membrane sterol content or by directly altering cellular zinc levels., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 14, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VTB4;Q6Q557", "ec_number_list": [], "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006882 intracellular zinc ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q03419-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03430-1", "uniprot_id": [ { "id": "RSM28_YEAST", "url": "https://www.uniprot.org/uniprot/Q03430", "type": "external" } ], "mass": 41216.0, "length": 361, "protein_name": "Small ribosomal subunit protein mS46", "gene_name": "RSM28", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein mS46 RSM28", "refseq_ac": [ { "id": "NP_010782", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010782", "type": "external" } ], "gene_names_uniprotkb": "RSM28", "gene_names_refseq": "RSM28; mS46", "protein_names_uniprotkb": "Small ribosomal subunit protein mS46; 37S ribosomal protein RSM28, mitochondrial", "protein_names_refseq": "mitochondrial 37S ribosomal protein mS46 RSM28", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR494W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "15701796;16823961;19684113;19779198;24374639;25609543;28154081;9169867", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTB6;Q8X184;Q8X185", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0070124 mitochondrial translational initiation;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q03430-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03441-1", "uniprot_id": [ { "id": "RMD1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03441", "type": "external" } ], "mass": 49932.0, "length": 430, "protein_name": "Sporulation protein RMD1", "gene_name": "RMD1", "organism": "Yeast", "refseq_name": "Rmd1p", "refseq_ac": [ { "id": "NP_010283", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010283", "type": "external" } ], "gene_names_uniprotkb": "RMD1", "gene_names_refseq": "RMD1", "protein_names_uniprotkb": "Sporulation protein RMD1; Required for meiotic nuclear division protein 1", "protein_names_refseq": "Rmd1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL001W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12586695;14562095;14562106;22814378;24374639;33229814;33491328;3537685;9169867", "class_list": "", "function": "Required for sporulation where it is believed to have a role in meiotic nuclear division., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VRY7;Q05210", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0051321 meiotic cell cycle;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q03441-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03483-1", "uniprot_id": [ { "id": "YD22A_YEAST", "url": "https://www.uniprot.org/uniprot/Q03483", "type": "external" } ], "mass": 49835.0, "length": 438, "protein_name": "Transposon Ty2-DR2 Gag polyprotein", "gene_name": "TY2A-DR2", "organism": "Yeast", "refseq_name": "gag protein", "refseq_ac": [ { "id": "NP_058143", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_058143", "type": "external" } ], "gene_names_uniprotkb": "TY2A-DR2; YD8142A.08; YDRWTy2-2 GAG", "gene_names_refseq": "", "protein_names_uniprotkb": "Transposon Ty2-DR2 Gag polyprotein; TY2A; TYA; Transposon Ty2 protein A", "protein_names_refseq": "gag protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR210W-A)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "16093660;17330950;24374639;9169867;9582191", "class_list": "", "function": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty2 RNA and initiation of reverse transcription (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSJ2", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q03483-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03496-1", "uniprot_id": [ { "id": "THADA_YEAST", "url": "https://www.uniprot.org/uniprot/Q03496", "type": "external" } ], "mass": 163577.0, "length": 1420, "protein_name": "tRNA (32-2'-O)-methyltransferase regulator TRM732", "gene_name": "TRM732", "organism": "Yeast", "refseq_name": "tRNA methylation protein TRM732", "refseq_ac": [ { "id": "NP_013986", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013986", "type": "external" } ], "gene_names_uniprotkb": "TRM732; YM8156.01C; YM9920.13C", "gene_names_refseq": "TRM732", "protein_names_uniprotkb": "tRNA (32-2'-O)-methyltransferase regulator TRM732", "protein_names_refseq": "tRNA methylation protein TRM732", "tax_id": 559292, "disease": "non-syndromic X-linked intellectual disability (Disease Ontology:DOID:0050776); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YMR259C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;14562106;19779198;22912484;24374639;26310293;29596413;33229814;35559166;9169872", "class_list": "", "function": "Together with methyltransferase TRM7, methylates the 2'-O-ribose of nucleotides at position 32 of the anticodon loop of substrate tRNAs., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6W085;Q04862", "ec_number_list": [], "go_molecular_function": "GO:0030234 enzyme regulator activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0002128 tRNA nucleoside ribose methylation;GO:0002130 wobble position ribose methylation", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q03496-1", "record_type": "protein", "filter_code": "0000000.0100111.010000.000000000000000010.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03516-1", "uniprot_id": [ { "id": "RSN1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03516", "type": "external" } ], "mass": 107673.0, "length": 953, "protein_name": "Uncharacterized protein RSN1", "gene_name": "RSN1", "organism": "Yeast", "refseq_name": "Rsn1p", "refseq_ac": [ { "id": "NP_013993", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013993", "type": "external" } ], "gene_names_uniprotkb": "RSN1; YM8156.08", "gene_names_refseq": "RSN1", "protein_names_uniprotkb": "Uncharacterized protein RSN1; Rescuer of SRO7 at high Nacl protein 1", "protein_names_refseq": "Rsn1p", "tax_id": 559292, "disease": "hypomyelinating leukodystrophy 19 (Disease Ontology:DOID:0070400); central nervous system disease (Disease Ontology:DOID:331)", "pathway": " (sce:YMR266W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "17005914;17287358;18407956;19779198;23749301;24374639;32597660;33481703;33491328;9169872", "class_list": "", "function": "Acts as an osmosensitive calcium-permeable cation channel., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W092", "ec_number_list": [], "go_molecular_function": "GO:0005227 calcium-activated cation channel activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0071944 cell periphery;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q03516-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03525-1", "uniprot_id": [ { "id": "TMA23_YEAST", "url": "https://www.uniprot.org/uniprot/Q03525", "type": "external" } ], "mass": 23949.0, "length": 211, "protein_name": "Protein TMA23", "gene_name": "TMA23", "organism": "Yeast", "refseq_name": "Tma23p", "refseq_ac": [ { "id": "NP_013996", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013996", "type": "external" } ], "gene_names_uniprotkb": "TMA23; YM8156.11; YMR268W-A", "gene_names_refseq": "TMA23; YMR268W-A", "protein_names_uniprotkb": "Protein TMA23; 23 kDa translation machinery-associated protein", "protein_names_refseq": "Tma23p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR269W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12844361;14562095;16702403;17425675;24374639;32597660;33481703;33491328;9169872", "class_list": "", "function": "Trans-acting factors of the ribosome biogenesis process., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W095;Q7Z870", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005730 nucleolus", "go_biological_process": "GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q03525-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03530-1", "uniprot_id": [ { "id": "RCE1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03530", "type": "external" } ], "mass": 35911.0, "length": 315, "protein_name": "CAAX prenyl protease 2", "gene_name": "RCE1", "organism": "Yeast", "refseq_name": "CAAX prenyl protease", "refseq_ac": [ { "id": "NP_014001", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014001", "type": "external" } ], "gene_names_uniprotkb": "RCE1; YM8156.16C", "gene_names_refseq": "RCE1", "protein_names_uniprotkb": "CAAX prenyl protease 2; 3.4.26.1; PPSEP 2; Prenyl protein-specific endoprotease 2; RACE; Ras and A-factor-converting enzyme", "protein_names_refseq": "CAAX prenyl protease", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR274C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10825201;11581258;16361710;16847258;24374639;9065405;9169872;9736709", "class_list": "", "function": "Protease involved in the processing of a variety of prenylated proteins containing the C-terminal CAAX motif, where C is a cysteine modified with an isoprenoid lipid, A is an aliphatic amino acid and X is any C-terminal amino acid. Proteolytically removes the C-terminal three residues of farnesylated proteins, leaving the prenylated cysteine as the new C-terminus. Target proteins include the a-factor mating pheromone and RAS. Its substrate specificity is overlapping but distinct with that of STE24., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0A1", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0071586 CAAX-box protein processing;GO:0019236 response to pheromone;GO:0007323 peptide pheromone maturation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q03530-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03652-1", "uniprot_id": [ { "id": "DML1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03652", "type": "external" } ], "mass": 55312.0, "length": 475, "protein_name": "Protein DML1", "gene_name": "DML1", "organism": "Yeast", "refseq_name": "Dml1p", "refseq_ac": [ { "id": "NP_013938", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013938", "type": "external" } ], "gene_names_uniprotkb": "DML1; YM8261.05", "gene_names_refseq": "DML1", "protein_names_uniprotkb": "Protein DML1; Drosophila melanogaster misato-like protein 1", "protein_names_refseq": "Dml1p", "tax_id": 559292, "disease": "myotonia congenita (Disease Ontology:DOID:2106)", "pathway": " (sce:YMR211W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12702300;14690591;24374639;9169872", "class_list": "", "function": "Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W036", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0007005 mitochondrion organization;GO:0006276 plasmid maintenance", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q03652-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03661-1", "uniprot_id": [ { "id": "ESC1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03661", "type": "external" } ], "mass": 187138.0, "length": 1658, "protein_name": "Silent chromatin protein ESC1", "gene_name": "ESC1", "organism": "Yeast", "refseq_name": "Esc1p", "refseq_ac": [ { "id": "NP_013946", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013946", "type": "external" } ], "gene_names_uniprotkb": "ESC1; YM8261.13; YM9959.01", "gene_names_refseq": "ESC1", "protein_names_uniprotkb": "Silent chromatin protein ESC1; Establishes silent chromatin protein 1", "protein_names_refseq": "Esc1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR219W)", "pathway_count": 1, "publication_count": 26, "publication_id_list": "12417731;14562095;15014445;15620354;15665377;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20190278;20702584;21126336;21177495;22218487;22814378;23749301;24374639;30516470;32597660;33481703;33491328;9169872", "class_list": "", "function": "Involved in the clustering of telomeres at the nuclear periphery, forming discrete subcompartments that accumulate a complex of histone-binding silencing factors like SIR4. Required for SIR4-mediated anchoring and partitioning of plasmids., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 116, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W044;Q04988", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0034399 nuclear periphery;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0031509 subtelomeric heterochromatin formation;GO:0006351 DNA-templated transcription;GO:0034398 telomere tethering at nuclear periphery", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "Q03661-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03667-1", "uniprot_id": [ { "id": "MIX17_YEAST", "url": "https://www.uniprot.org/uniprot/Q03667", "type": "external" } ], "mass": 16669.0, "length": 156, "protein_name": "Mitochondrial intermembrane space cysteine motif-containing protein MIX17", "gene_name": "MIX17", "organism": "Yeast", "refseq_name": "Mix17p", "refseq_ac": [ { "id": "NP_013715", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013715", "type": "external" } ], "gene_names_uniprotkb": "MIX17; MIC17; YM8270.04", "gene_names_refseq": "MIC17; MIX17", "protein_names_uniprotkb": "Mitochondrial intermembrane space cysteine motif-containing protein MIX17; Mitochondrial intermembrane space CX(n)C motif protein of 17 kDa", "protein_names_refseq": "Mix17p", "tax_id": 559292, "disease": "frontotemporal dementia and/or amyotrophic lateral sclerosis 2 (Disease Ontology:DOID:0060214); Parkinson's disease 22 (Disease Ontology:DOID:0080504); spinal muscular atrophy, Jokela type (Disease Ontology:DOID:0081356); isolated mitochondrial myopathy (Disease Ontology:DOID:0081357); Parkinson's disease (Disease Ontology:DOID:14330); motor neuron disease (Disease Ontology:DOID:231); amyotrophic lateral sclerosis (Disease Ontology:DOID:332)", "pathway": " (sce:YMR002W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562106;17095012;17322287;21177495;22984289;23749301;24374639;24687277;32597660;9169872", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZH7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0007005 mitochondrion organization;GO:0009060 aerobic respiration", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q03667-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03673-1", "uniprot_id": [ { "id": "AIM34_YEAST", "url": "https://www.uniprot.org/uniprot/Q03673", "type": "external" } ], "mass": 22742.0, "length": 198, "protein_name": "Altered inheritance of mitochondria protein 34, mitochondrial", "gene_name": "AIM34", "organism": "Yeast", "refseq_name": "Aim34p", "refseq_ac": [ { "id": "NP_013716", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013716", "type": "external" } ], "gene_names_uniprotkb": "AIM34; YM8270.05", "gene_names_refseq": "AIM34", "protein_names_uniprotkb": "Altered inheritance of mitochondria protein 34, mitochondrial", "protein_names_refseq": "Aim34p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR003W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562095;14562106;19300474;24374639;9169872", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZH8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0031966 mitochondrial membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q03673-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03697-1", "uniprot_id": [ { "id": "YMD8_YEAST", "url": "https://www.uniprot.org/uniprot/Q03697", "type": "external" } ], "mass": 49615.0, "length": 442, "protein_name": "Putative nucleotide-sugar transporter YMD8", "gene_name": "YMD8", "organism": "Yeast", "refseq_name": "Ymd8p", "refseq_ac": [ { "id": "NP_013674", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013674", "type": "external" } ], "gene_names_uniprotkb": "YMD8", "gene_names_refseq": "YMD8", "protein_names_uniprotkb": "Putative nucleotide-sugar transporter YMD8", "protein_names_refseq": "Ymd8p", "tax_id": 559292, "disease": "", "pathway": " (sce:YML038C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;16847258;17322287;19779198;24374639;9169872", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VZD7", "ec_number_list": [], "go_molecular_function": "GO:0015297 antiporter activity;GO:0005338 nucleotide-sugar transmembrane transporter activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0030137 COPI-coated vesicle;GO:0005801 cis-Golgi network;GO:0005793 endoplasmic reticulum-Golgi intermediate compartment", "go_biological_process": "GO:0015786 UDP-glucose transmembrane transport;GO:0015780 nucleotide-sugar transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q03697-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03760-1", "uniprot_id": [ { "id": "PML39_YEAST", "url": "https://www.uniprot.org/uniprot/Q03760", "type": "external" } ], "mass": 39207.0, "length": 334, "protein_name": "Pre-mRNA leakage protein 39", "gene_name": "PML39", "organism": "Yeast", "refseq_name": "Pml39p", "refseq_ac": [ { "id": "NP_013600", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013600", "type": "external" } ], "gene_names_uniprotkb": "PML39; YM8339.12", "gene_names_refseq": "PML39", "protein_names_uniprotkb": "Pre-mRNA leakage protein 39; 39 kDa pre-mRNA leakage protein", "protein_names_refseq": "Pml39p", "tax_id": 559292, "disease": "", "pathway": " (sce:YML107C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12748633;14562095;14562106;16162818;24374639;9169872", "class_list": "", "function": "Involved in the nuclear retention of improperly spliced pre-mRNAs., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0H7", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0044615 nuclear pore nuclear basket;GO:0031965 nuclear membrane", "go_biological_process": "GO:0051028 mRNA transport;GO:0051237 maintenance of RNA location", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q03760-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03764-1", "uniprot_id": [ { "id": "EKI1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03764", "type": "external" } ], "mass": 61657.0, "length": 534, "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "organism": "Yeast", "refseq_name": "bifunctional choline kinase/ethanolamine kinase EKI1", "refseq_ac": [ { "id": "NP_010431", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010431", "type": "external" } ], "gene_names_uniprotkb": "EKI1; YD8358.04", "gene_names_refseq": "EKI1", "protein_names_uniprotkb": "Ethanolamine kinase; 2.7.1.82; EK", "protein_names_refseq": "bifunctional choline kinase/ethanolamine kinase EKI1", "tax_id": 559292, "disease": "colon adenoma (Disease Ontology:DOID:0050912); megaconial type congenital muscular dystrophy (Disease Ontology:DOID:0110632); intellectual disability (Disease Ontology:DOID:1059); colon cancer (Disease Ontology:DOID:219); transient cerebral ischemia (Disease Ontology:DOID:224); recurrent hypersomnia (Disease Ontology:DOID:8619); narcolepsy (Disease Ontology:DOID:8986); muscular dystrophy (Disease Ontology:DOID:9884)", "pathway": " (sce:YDR147W); (R-SCE-1483191); (R-SCE-1483213)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10329685;14562095;14562106;15201274;16551612;18407956;23749301;24374639;33481703;33491328;9169867", "class_list": "", "function": "Catalyzes the committed step of phosphatidylethanolamine synthesis via the CDP-ethanolamine branch of the Kennedy pathway. Also exhibits choline kinase activity, thus contributing to phosphatidylcholine synthesis via the CDP-choline pathway, but its preferred substrate is ethanolamine., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSD0", "ec_number_list": [ { "id": "2.7.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.32", "type": "external" }, { "id": "2.7.1.82", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.82", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004103 choline kinase activity;GO:0004305 ethanolamine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006656 phosphatidylcholine biosynthetic process;GO:0006646 phosphatidylethanolamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q03764-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03770-1", "uniprot_id": [ { "id": "SSY1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03770", "type": "external" } ], "mass": 95744.0, "length": 852, "protein_name": "SPS-sensor component SSY1", "gene_name": "SSY1", "organism": "Yeast", "refseq_name": "Ssy1p", "refseq_ac": [ { "id": "NP_010444", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010444", "type": "external" } ], "gene_names_uniprotkb": "SSY1; APF7; SHR10; YD8358.14", "gene_names_refseq": "RAA1; SHR10; SSY1", "protein_names_uniprotkb": "SPS-sensor component SSY1; Amino-acid permease homolog SSY1", "protein_names_refseq": "Ssy1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR160W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10409731;11154269;11679080;12073087;12502738;14555474;16847258;17984223;24374639;33491328;9169867;9483800;9489675;9891035", "class_list": "", "function": "Amino acid sensor component of the SPS-sensor system, which regulates the expression of several amino acid-metabolizing enzymes and amino acid- and peptide-permeases in response to extracellular amino acid levels by controlling the activity of two transcription factors, STP1 and STP2. Amino-acid permease homolog that seems to interact directly with the extracellular signaling molecules, but has no amino acid transporter activity. May recruit casein kinases YCK1 and YCK2 to hyperphosphorylate and activate downstream component PTR3 in response to amino acid stimulus., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSE0", "ec_number_list": [], "go_molecular_function": "GO:0015171 amino acid transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0043200 response to amino acid;GO:0003333 amino acid transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q03770-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03776-1", "uniprot_id": [ { "id": "PRP42_YEAST", "url": "https://www.uniprot.org/uniprot/Q03776", "type": "external" } ], "mass": 65145.0, "length": 544, "protein_name": "U1 small nuclear ribonucleoprotein component PRP42", "gene_name": "PRP42", "organism": "Yeast", "refseq_name": "mRNA splicing protein PRP42", "refseq_ac": [ { "id": "NP_010521", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010521", "type": "external" } ], "gene_names_uniprotkb": "PRP42; MUD16; SNU65; YD8419.02", "gene_names_refseq": "MUD16; PRP42; SNU65", "protein_names_uniprotkb": "U1 small nuclear ribonucleoprotein component PRP42; 65 kDa snRNP protein; Pre-mRNA-processing factor 42; U1 snRNP protein PRP42", "protein_names_refseq": "mRNA splicing protein PRP42", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR235W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10504710;11804584;12897147;14562095;14562106;24374639;33491328;9169867;9418882;9630245", "class_list": "", "function": "Essential component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway. U1 snRNP is cotranscriptionally recruited to intron-containing genes. Required for U1 snRNP biogenesis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSL6", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0005634 nucleus;GO:0000243 commitment complex;GO:0071004 U2-type prespliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0000395 mRNA 5'-splice site recognition", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q03776-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03782-1", "uniprot_id": [ { "id": "SNU56_YEAST", "url": "https://www.uniprot.org/uniprot/Q03782", "type": "external" } ], "mass": 56498.0, "length": 492, "protein_name": "56 kDa U1 small nuclear ribonucleoprotein component", "gene_name": "SNU56", "organism": "Yeast", "refseq_name": "Snu56p", "refseq_ac": [ { "id": "NP_010526", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010526", "type": "external" } ], "gene_names_uniprotkb": "SNU56; MUD10", "gene_names_refseq": "MUD10; SNU56", "protein_names_uniprotkb": "56 kDa U1 small nuclear ribonucleoprotein component", "protein_names_refseq": "Snu56p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR240C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10072386;10490594;11804584;14562095;14562106;17322287;19779198;23749301;24374639;24440502;33491328;9169867;9630245", "class_list": "", "function": "Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSM1", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0005634 nucleus;GO:0000243 commitment complex;GO:0071004 U2-type prespliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0000395 mRNA 5'-splice site recognition", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q03782-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03786-1", "uniprot_id": [ { "id": "GNTK_YEAST", "url": "https://www.uniprot.org/uniprot/Q03786", "type": "external" } ], "mass": 22175.0, "length": 193, "protein_name": "Probable gluconokinase", "gene_name": "", "organism": "Yeast", "refseq_name": "gluconokinase", "refseq_ac": [ { "id": "NP_010534", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_010534", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable gluconokinase; 2.7.1.12; Gluconate kinase", "protein_names_refseq": "gluconokinase", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR248C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "14562095;14562106;24374639;9169867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSM9", "ec_number_list": [ { "id": "2.7.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.12", "type": "external" } ], "go_molecular_function": "GO:0046316 gluconokinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0019521 D-gluconate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q03786-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03792-1", "uniprot_id": [ { "id": "RIM13_YEAST", "url": "https://www.uniprot.org/uniprot/Q03792", "type": "external" } ], "mass": 83124.0, "length": 727, "protein_name": "Calpain-like protease 1", "gene_name": "RIM13", "organism": "Yeast", "refseq_name": "Rim13p", "refseq_ac": [ { "id": "NP_013875", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013875", "type": "external" } ], "gene_names_uniprotkb": "RIM13; CPL1; YM8520.03C", "gene_names_refseq": "CPL1; RIM13", "protein_names_uniprotkb": "Calpain-like protease 1; 3.4.22.-; Calpain-7; Cysteine protease RIM13; Regulator of IME2 protein 13", "protein_names_refseq": "Rim13p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR154C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11050096;11283351;14562106;24374639;9017390;9169872;9928935", "class_list": "", "function": "Required for the proteolytic cleavage of the transcriptional repressor RIM101 in response to alkaline ambient pH, which is necessary for sporulation and invasive growth. Probably the protease that cleaves RIM101., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZX5", "ec_number_list": [], "go_molecular_function": "GO:0004198 calcium-dependent cysteine-type endopeptidase activity;GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "", "go_biological_process": "GO:0006508 proteolysis;GO:0016485 protein processing", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q03792-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000010.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03796-1", "uniprot_id": [ { "id": "TPP1_YEAST", "url": "https://www.uniprot.org/uniprot/Q03796", "type": "external" } ], "mass": 27383.0, "length": 238, "protein_name": "Polynucleotide 3'-phosphatase", "gene_name": "TPP1", "organism": "Yeast", "refseq_name": "polynucleotide 3'-phosphatase", "refseq_ac": [ { "id": "NP_013877", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013877", "type": "external" } ], "gene_names_uniprotkb": "TPP1; YM8520.05C", "gene_names_refseq": "TPP1", "protein_names_uniprotkb": "Polynucleotide 3'-phosphatase; 2'(3')-polynucleotidase; 3.1.3.32; DNA 3'-phosphatase; Three prime phosphatase", "protein_names_refseq": "polynucleotide 3'-phosphatase", "tax_id": 559292, "disease": "microcephaly, seizures, and developmental delay (Disease Ontology:DOID:0080457); ataxia-oculomotor apraxia 4 (Disease Ontology:DOID:0081383); Charcot-Marie-Tooth disease type 2B2 (Disease Ontology:DOID:0110179)", "pathway": " (sce:YMR156C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11278831;17322287;24374639;33491328;9169872", "class_list": "", "function": "Dephosphorylate DNA's 3'-phosphate termini. Has a role in the repair of breaks in single-stranded DNA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZX7", "ec_number_list": [ { "id": "3.1.3.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.32", "type": "external" } ], "go_molecular_function": "GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity;GO:0003690 double-stranded DNA binding;GO:0046403 polynucleotide 3'-phosphatase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006281 DNA repair;GO:0006302 double-strand break repair", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q03796-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03798-1", "uniprot_id": [ { "id": "AIM36_YEAST", "url": "https://www.uniprot.org/uniprot/Q03798", "type": "external" } ], "mass": 29077.0, "length": 255, "protein_name": "Altered inheritance of mitochondria protein 36, mitochondrial", "gene_name": "AIM36", "organism": "Yeast", "refseq_name": "Aim36p", "refseq_ac": [ { "id": "NP_013878", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_013878", "type": "external" } ], "gene_names_uniprotkb": "AIM36; FMP39; YM8520.06C", "gene_names_refseq": "AIM36; FMP39", "protein_names_uniprotkb": "Altered inheritance of mitochondria protein 36, mitochondrial; Found in mitochondrial proteome protein 39", "protein_names_refseq": "Aim36p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR157C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;19300474;19779198;19795423;19823750;24374639;9169872", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZX8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0031966 mitochondrial membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q03798-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000010.0000000000001.000.00000", "kg_view_protein": true } ]