[ { "uniprot_canonical_ac": "A0AB32TJT0-1", "uniprot_id": [ { "id": "A0AB32TJT0_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TJT0", "type": "external" } ], "mass": 135820.0, "length": 1260, "protein_name": "Poly [ADP-ribose] polymerase", "gene_name": "tnksa", "organism": "Zebrafish", "refseq_name": "poly [ADP-ribose] polymerase tankyrase-1 isoform X1", "refseq_ac": [ { "id": "XP_068075061", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068075061", "type": "external" } ], "gene_names_uniprotkb": "tnksa", "gene_names_refseq": "tnksa", "protein_names_uniprotkb": "Poly [ADP-ribose] polymerase; 2.4.2.-; PARP", "protein_names_refseq": "poly [ADP-ribose] polymerase tankyrase-1 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068075061.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0016779 nucleotidyltransferase activity;GO:0003950 NAD+ poly-ADP-ribosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0016055 Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32TJT0-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FXR9-1", "uniprot_id": [ { "id": "A0AC58FXR9_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FXR9", "type": "external" } ], "mass": 77959.0, "length": 703, "protein_name": "Si:ch211-165f21.7 isoform X1", "gene_name": "si:ch211-165f21.2", "organism": "Zebrafish", "refseq_name": "si:ch211-165f21.7 isoform X1", "refseq_ac": [ { "id": "XP_073762157", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073762157", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-165f21.2; Lirb3; si:ch211-165f21.7", "gene_names_refseq": "PirB/Lirb3; si:ch211-165f21.2; si:ch211-165f21.7", "protein_names_uniprotkb": "Si:ch211-165f21.7 isoform X1", "protein_names_refseq": "si:ch211-165f21.7 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100320788)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "20007473;21873635;28252024", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0AC58FXR9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FWK7-1", "uniprot_id": [ { "id": "A0AC58FWK7_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FWK7", "type": "external" } ], "mass": 72953.0, "length": 641, "protein_name": "ATP-binding cassette sub-family F member 2", "gene_name": "abcf2b", "organism": "Zebrafish", "refseq_name": "ATP-binding cassette, sub-family F, member 2b isoform X1", "refseq_ac": [ { "id": "XP_073762002", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073762002", "type": "external" } ], "gene_names_uniprotkb": "abcf2b; im:6902464; si:ch211-198h5.3", "gene_names_refseq": "abcf2b; im:6902464; si:ch211-198h5.3", "protein_names_uniprotkb": "ATP-binding cassette sub-family F member 2", "protein_names_refseq": "ATP-binding cassette, sub-family F, member 2b isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100000576)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "26047617;40044042", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0AC58FWK7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "uniprot_id": [ { "id": "A0AC58FXL6_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FXL6", "type": "external" } ], "mass": 63082.0, "length": 552, "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "cyp2x10.2; wu:fb64f09; zgc:136371", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytochrome P450 2X10.2 isoform X2", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:322545)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21087487;22046393", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0AC58FXL6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FYM8-1", "uniprot_id": [ { "id": "A0AC58FYM8_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FYM8", "type": "external" } ], "mass": 31367.0, "length": 290, "protein_name": "Copper chaperone for superoxide dismutase", "gene_name": "ccs", "organism": "Zebrafish", "refseq_name": "copper chaperone for superoxide dismutase isoform X1", "refseq_ac": [ { "id": "XP_073762658", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073762658", "type": "external" } ], "gene_names_uniprotkb": "ccs; zgc:112427", "gene_names_refseq": "ccs; zgc:112427", "protein_names_uniprotkb": "Copper chaperone for superoxide dismutase; Superoxide dismutase copper chaperone", "protein_names_refseq": "copper chaperone for superoxide dismutase isoform X1", "tax_id": 7955, "disease": "amyotrophic lateral sclerosis (Disease Ontology:DOID:332)", "pathway": " (dre:550489); (R-DRE-3299685)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "32670800;35295584", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Delivers copper to copper zinc superoxide dismutase (SOD1)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005507 copper ion binding;GO:0016532 superoxide dismutase copper chaperone activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0019430 removal of superoxide radicals", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0AC58FYM8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FXL4-1", "uniprot_id": [ { "id": "A0AC58FXL4_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FXL4", "type": "external" } ], "mass": 160374.0, "length": 1679, "protein_name": "Collagen alpha-5(IV) chain isoform X1", "gene_name": "col4a5", "organism": "Zebrafish", "refseq_name": "collagen alpha-5(IV) chain isoform X1", "refseq_ac": [ { "id": "XP_073762287", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073762287", "type": "external" } ], "gene_names_uniprotkb": "col4a5; col4a1; wu:fc02g11", "gene_names_refseq": "col4a1; col4a5; wu:fc02g11", "protein_names_uniprotkb": "Collagen alpha-5(IV) chain isoform X1", "protein_names_refseq": "collagen alpha-5(IV) chain isoform X1", "tax_id": 7955, "disease": "X-linked Alport syndrome (Disease Ontology:DOID:0110034); Alport syndrome (Disease Ontology:DOID:10983); dilated cardiomyopathy (Disease Ontology:DOID:12930); proteinuria (Disease Ontology:DOID:576)", "pathway": " (dre:323561)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "15520368;16109975;17982451;21191402;21729787;35716957;35782869;36244504;37002899;37024546", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005201 extracellular matrix structural constituent", "go_cellular_component": "GO:0005604 basement membrane;GO:0005581 collagen trimer", "go_biological_process": "GO:0030198 extracellular matrix organization;GO:0031290 retinal ganglion cell axon guidance;GO:0071711 basement membrane organization;GO:0048846 axon extension involved in axon guidance;GO:0007412 axon target recognition", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "A0AC58FXL4-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TXZ5-1", "uniprot_id": [ { "id": "A0AB32TXZ5_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TXZ5", "type": "external" } ], "mass": 78776.0, "length": 711, "protein_name": "long-chain-fatty-acid--CoA ligase", "gene_name": "acsl3b", "organism": "Zebrafish", "refseq_name": "long-chain-fatty-acid--CoA ligase 3b", "refseq_ac": [ { "id": "NP_001139404", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139404", "type": "external" } ], "gene_names_uniprotkb": "acsl3b; acsl3; fa07a08; im:7155129; si:dkey-20f20.5; wu:fa07a08; wu:fb34c03", "gene_names_refseq": "acsl3b; acsl3; fa07a08; im:7155129; si:dkey-20f20.5; wu:fa07a08; wu:fb34c03", "protein_names_uniprotkb": "long-chain-fatty-acid--CoA ligase; 6.2.1.3", "protein_names_refseq": "acyl-CoA synthetase long-chain family member 3; long-chain-fatty-acid--CoA ligase 3b", "tax_id": 7955, "disease": "non-syndromic X-linked intellectual disability (Disease Ontology:DOID:0050776); non-syndromic X-linked intellectual disability 63 (Disease Ontology:DOID:0112050); prostate cancer (Disease Ontology:DOID:10283); lung cancer (Disease Ontology:DOID:1324); Sjogren-Larsson syndrome (Disease Ontology:DOID:14501); breast cancer (Disease Ontology:DOID:1612); asthma (Disease Ontology:DOID:2841)", "pathway": " (dre:559656); (R-DRE-434313); (R-DRE-75876)", "pathway_count": 3, "publication_count": 10, "publication_id_list": "17762044;18417109;24330521;25030662;26469318;27671199;28252024;29209275;32691447;34016526", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588732.22641265.1, SRR26395015.1361160.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476804, SAMEA708828 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000002.1. On Jun 5, 2025 this sequence version replaced NP_001139404.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58GXG5", "ec_number_list": [ { "id": "6.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.3", "type": "external" }, { "id": "6.2.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.15", "type": "external" } ], "go_molecular_function": "GO:0004467 long-chain fatty acid-CoA ligase activity;GO:0016874 ligase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005811 lipid droplet;GO:0005886 plasma membrane", "go_biological_process": "GO:0001676 long-chain fatty acid metabolic process;GO:0030182 neuron differentiation;GO:0035336 long-chain fatty-acyl-CoA metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "A0AB32TXZ5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FXL5-1", "uniprot_id": [ { "id": "A0AC58FXL5_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FXL5", "type": "external" } ], "mass": 80209.0, "length": 700, "protein_name": "U3 small nucleolar ribonucleoprotein protein MPP10", "gene_name": "mphosph10", "organism": "Zebrafish", "refseq_name": "U3 small nucleolar ribonucleoprotein MPP10", "refseq_ac": [ { "id": "NP_001292472", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292472", "type": "external" } ], "gene_names_uniprotkb": "mphosph10; fb98b07; wu:fb98b07", "gene_names_refseq": "fb98b07; mphosph10; wu:fb98b07", "protein_names_uniprotkb": "U3 small nucleolar ribonucleoprotein protein MPP10", "protein_names_refseq": "U3 small nucleolar ribonucleoprotein MPP10", "tax_id": 7955, "disease": "", "pathway": " (dre:323426)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "16109975;26311515;26469318;30773582;34162866", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588734.2129040.1, SRR26395063.893137.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505380, SAMEA3505381 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On or before Jul 23, 2025 this sequence version replaced XP_073762284.1, NP_001292472.2., [RefSeq]; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing., [UniProtKB, UniProtKB, UniProtKB]; Sas10 is essential not only for delivering the Mpp10-Imp3-Imp4 complex to the nucleolus for assembling the SSU processome but also for fine-tuning Mpp10 turnover in the nucleolus during organogenesis., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005732 sno(s)RNA-containing ribonucleoprotein complex;GO:0034457 Mpp10 complex;GO:0032040 small-subunit processome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006364 rRNA processing;GO:0055123 digestive system development", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0AC58FXL5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32U4L1-1", "uniprot_id": [ { "id": "A0AB32U4L1_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32U4L1", "type": "external" } ], "mass": 40533.0, "length": 369, "protein_name": "Probable endonuclease 4 isoform X1", "gene_name": "si:ch211-141o9.10", "organism": "Zebrafish", "refseq_name": "probable endonuclease 4 isoform X1", "refseq_ac": [ { "id": "XP_068080860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068080860", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-141o9.10", "gene_names_refseq": "si:ch211-141o9.10", "protein_names_uniprotkb": "Probable endonuclease 4 isoform X1", "protein_names_refseq": "probable endonuclease 4 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068080860.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0016787 hydrolase activity;GO:0004519 endonuclease activity", "go_cellular_component": "", "go_biological_process": "GO:0006281 DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32U4L1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TJB3-1", "uniprot_id": [ { "id": "A0AB32TJB3_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TJB3", "type": "external" } ], "mass": 144181.0, "length": 1258, "protein_name": "Protein fantom isoform X1", "gene_name": "rpgrip1l", "organism": "Zebrafish", "refseq_name": "protein fantom isoform X1", "refseq_ac": [ { "id": "XP_073798201", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073798201", "type": "external" } ], "gene_names_uniprotkb": "rpgrip1l; si:ch1073-301i20.1", "gene_names_refseq": "rpgrip1l; si:ch1073-301i20.1", "protein_names_uniprotkb": "Protein fantom isoform X1", "protein_names_refseq": "protein fantom isoform X1", "tax_id": 7955, "disease": "cerebellar ataxia (Disease Ontology:DOID:0050753); Meckel syndrome (Disease Ontology:DOID:0050778); ciliopathy (Disease Ontology:DOID:0060340); anencephaly (Disease Ontology:DOID:0060668); Meckel syndrome 5 (Disease Ontology:DOID:0070119); retinitis pigmentosa 3 (Disease Ontology:DOID:0110414); Joubert syndrome 7 (Disease Ontology:DOID:0111002); intellectual disability (Disease Ontology:DOID:1059); nephronophthisis (Disease Ontology:DOID:12712); cystic kidney disease (Disease Ontology:DOID:2975); vascular dementia (Disease Ontology:DOID:8725)", "pathway": " (dre:557688); (R-DRE-5610787)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "19430481;21258341;22927466;26469318;27189481;33435938;35861640;36533556;37352572;39388365", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58IVE5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0032391 photoreceptor connecting cilium", "go_biological_process": "GO:0046548 retinal rod cell development;GO:1905515 non-motile cilium assembly;GO:0009880 embryonic pattern specification", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "A0AB32TJB3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FXC8-1", "uniprot_id": [ { "id": "A0AC58FXC8_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FXC8", "type": "external" } ], "mass": 58298.0, "length": 531, "protein_name": "5-hydroxytryptamine (Serotonin) receptor 2C, G protein-coupled-like 1 isoform X1", "gene_name": "htr2cl1", "organism": "Zebrafish", "refseq_name": "5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1 isoform X1", "refseq_ac": [ { "id": "XP_073762008", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073762008", "type": "external" } ], "gene_names_uniprotkb": "htr2cl1; 5-ht2cr; si:dkey-24g18.2", "gene_names_refseq": "5-ht2cr; htr2cl1; si:dkey-24g18.2", "protein_names_uniprotkb": "5-hydroxytryptamine (Serotonin) receptor 2C, G protein-coupled-like 1 isoform X1", "protein_names_refseq": "5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1 isoform X1", "tax_id": 7955, "disease": "nicotine dependence (Disease Ontology:DOID:0050742); withdrawal disorder (Disease Ontology:DOID:0060001); autism spectrum disorder (Disease Ontology:DOID:0060041); Prader-Willi syndrome (Disease Ontology:DOID:11983); major depressive disorder (Disease Ontology:DOID:1470); alcohol use disorder (Disease Ontology:DOID:1574); anxiety disorder (Disease Ontology:DOID:2030); asthma (Disease Ontology:DOID:2841); substance-related disorder (Disease Ontology:DOID:303); bipolar disorder (Disease Ontology:DOID:3312); schizophrenia (Disease Ontology:DOID:5419); cocaine abuse (Disease Ontology:DOID:809); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970); cocaine dependence (Disease Ontology:DOID:9975)", "pathway": " (dre:100000981)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004993 G protein-coupled serotonin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58FXC8-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TRG7-1", "uniprot_id": [ { "id": "A0AB32TRG7_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TRG7", "type": "external" } ], "mass": 30080.0, "length": 273, "protein_name": "Uncharacterized protein isoform X1", "gene_name": "LOC101884708", "organism": "Zebrafish", "refseq_name": "uncharacterized protein isoform X1", "refseq_ac": [ { "id": "XP_068076533", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068076533", "type": "external" } ], "gene_names_uniprotkb": "LOC101884708", "gene_names_refseq": "LOC101884708", "protein_names_uniprotkb": "Uncharacterized protein isoform X1", "protein_names_refseq": "uncharacterized protein isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:101884708)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068076533.1. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0AC58FXE1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FX91-1", "uniprot_id": [ { "id": "A0AC58FX91_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FX91", "type": "external" } ], "mass": 52596.0, "length": 473, "protein_name": "Caspase activity and apoptosis inhibitor 1 isoform X1", "gene_name": "caap1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "caap1", "gene_names_refseq": "", "protein_names_uniprotkb": "Caspase activity and apoptosis inhibitor 1 isoform X1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:100329847)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0042981 regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58FX91-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FYW2-1", "uniprot_id": [ { "id": "A0AC58FYW2_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FYW2", "type": "external" } ], "mass": 14995.0, "length": 133, "protein_name": "Plac8 onzin related protein 5 isoform X1", "gene_name": "ponzr5", "organism": "Zebrafish", "refseq_name": "plac8 onzin related protein 5 isoform X1", "refseq_ac": [ { "id": "XP_073762732", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073762732", "type": "external" } ], "gene_names_uniprotkb": "ponzr5; si:dkey-165a24.3", "gene_names_refseq": "ponzr5; si:dkey-165a24.3", "protein_names_uniprotkb": "Plac8 onzin related protein 5 isoform X1", "protein_names_refseq": "plac8 onzin related protein 5 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:556869)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "22274699;27189481;31030196", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58FYW4;A0AC58FYX1;A0AC58FZB0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0AC58FYW2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FYE5-1", "uniprot_id": [ { "id": "A0AC58FYE5_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FYE5", "type": "external" } ], "mass": 24310.0, "length": 213, "protein_name": "RWD domain-containing protein 4 isoform X1", "gene_name": "rwdd", "organism": "Zebrafish", "refseq_name": "RWD domain-containing protein 4 isoform X1", "refseq_ac": [ { "id": "XP_073762557", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073762557", "type": "external" } ], "gene_names_uniprotkb": "rwdd; si:ch211-192e21.1; zgc:103545", "gene_names_refseq": "rwdd; si:ch211-192e21.1; zgc:103545", "protein_names_uniprotkb": "RWD domain-containing protein 4 isoform X1", "protein_names_refseq": "RWD domain-containing protein 4 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:449812)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "26469318;32784920", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0AC58FYE5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TXV8-1", "uniprot_id": [ { "id": "A0AB32TXV8_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TXV8", "type": "external" } ], "mass": 25260.0, "length": 223, "protein_name": "Novel immune-type receptor 3d isoform X1", "gene_name": "nitr3d", "organism": "Zebrafish", "refseq_name": "novel immune-type receptor 3d precursor", "refseq_ac": [ { "id": "NP_938169", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_938169", "type": "external" } ], "gene_names_uniprotkb": "nitr3d; SI:dZ169I8.6; nitr3r.10; nitr3r.11; nitr3r.2; nitr3r.4; nitr3r.5; nitr3r.6; nitr3r.7; nitr3r.8; nitr3; si:dz186f8.1", "gene_names_refseq": "SI:dZ169I8.6; nitr3d; nitr3r.10; nitr3r.11; nitr3r.2; nitr3r.4; nitr3r.5; nitr3r.6; nitr3r.7; nitr3r.8; nitr3; si:dz186f8.1", "protein_names_uniprotkb": "Novel immune-type receptor 3d isoform X1", "protein_names_refseq": "immune-type receptor; novel immune-type receptor 3, related 2; novel immune-type receptor 3, related 4; novel immune-type receptor 3d precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:171006)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15496470;18565225;20012603", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01079852.1, SRR32588732.16441776.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505382, SAMEA3505385 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Jun 25, 2025 this sequence version replaced NP_938169.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0002376 immune system process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0AB32TXV8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32U4S8-1", "uniprot_id": [ { "id": "A0AB32U4S8_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32U4S8", "type": "external" } ], "mass": 89570.0, "length": 791, "protein_name": "Semaphorin-3F isoform X1", "gene_name": "sema3fb", "organism": "Zebrafish", "refseq_name": "semaphorin-3F isoform X1", "refseq_ac": [ { "id": "XP_068080490", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068080490", "type": "external" } ], "gene_names_uniprotkb": "sema3fb", "gene_names_refseq": "sema3fb", "protein_names_uniprotkb": "Semaphorin-3F isoform X1", "protein_names_refseq": "semaphorin-3F isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068080490.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030215 semaphorin receptor binding;GO:0038191 neuropilin binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane", "go_biological_process": "GO:0003170 heart valve development;GO:0007165 signal transduction;GO:0045765 regulation of angiogenesis;GO:0007411 axon guidance;GO:0097350 neutrophil clearance", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32U4S8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FX22-1", "uniprot_id": [ { "id": "A0AC58FX22_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FX22", "type": "external" } ], "mass": 494624.0, "length": 4556, "protein_name": "Zonadhesin, like isoform X1", "gene_name": "zanl", "organism": "Zebrafish", "refseq_name": "zonadhesin, like precursor", "refseq_ac": [ { "id": "NP_001352287", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352287", "type": "external" } ], "gene_names_uniprotkb": "zanl; unm_sa783; zan", "gene_names_refseq": "unm_sa783; zanl; zan", "protein_names_uniprotkb": "Zonadhesin, like isoform X1", "protein_names_refseq": "zonadhesin, like precursor; zonadhesin", "tax_id": 7955, "disease": "", "pathway": " (dre:100147904)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16303057;26469318", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA3505392, SAMEA4476736 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On or before Jul 22, 2025 this sequence version replaced XP_073762126.1, NP_001352287.2., [RefSeq]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0AC58FX22-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36JYR4-1", "uniprot_id": [ { "id": "A0AC36JYR4_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36JYR4", "type": "external" } ], "mass": 142639.0, "length": 1286, "protein_name": "RNA binding motif protein 16-like", "gene_name": "scaf8", "organism": "Zebrafish", "refseq_name": "SR-related and CTD-associated factor 8", "refseq_ac": [ { "id": "NP_001423676", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001423676", "type": "external" } ], "gene_names_uniprotkb": "scaf8; fc50c06; fd99c08; wu:fc50c06; wu:fd99c08", "gene_names_refseq": "fc50c06; fd99c08; scaf8; wu:fc50c06; wu:fd99c08", "protein_names_uniprotkb": "RNA binding motif protein 16-like", "protein_names_refseq": "SR-related and CTD-associated factor 8", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395028.804630.1, ERR4321680.236889.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505377, SAMEA3505378 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000017.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC36JYR4-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36JW60-1", "uniprot_id": [ { "id": "A0AC36JW60_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36JW60", "type": "external" } ], "mass": 54779.0, "length": 488, "protein_name": "Lysyl oxidase homolog", "gene_name": "loxl5a", "organism": "Zebrafish", "refseq_name": "lysyl oxidase-like 5a precursor", "refseq_ac": [ { "id": "NP_001424462", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001424462", "type": "external" } ], "gene_names_uniprotkb": "loxl5a; si:ch211-63j24.5; si:dkey-49m19.3", "gene_names_refseq": "loxl5a; si:ch211-63j24.5; si:dkey-49m19.3", "protein_names_uniprotkb": "Lysyl oxidase homolog; 1.4.3.13", "protein_names_refseq": "lysyl oxidase-like 5a precursor", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "17543297", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588731.264263.1, SRR32588732.12303182.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN18715719 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On Apr 3, 2025 this sequence version replaced XP_068072453.1., [RefSeq]; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.4.3.13", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.13", "type": "external" }, { "id": "1.4.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.-", "type": "external" } ], "go_molecular_function": "GO:0004720 protein-lysine 6-oxidase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0AC36JW60-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36K3U2-1", "uniprot_id": [ { "id": "A0AC36K3U2_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36K3U2", "type": "external" } ], "mass": 27446.0, "length": 246, "protein_name": "Vesicle-associated membrane protein-associated protein A", "gene_name": "vapa", "organism": "Zebrafish", "refseq_name": "vesicle-associated membrane protein-associated protein A isoform 1", "refseq_ac": [ { "id": "NP_956212", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956212", "type": "external" } ], "gene_names_uniprotkb": "vapa; wu:fa14e12; zgc:65776; zgc:77382", "gene_names_refseq": "vapa; wu:fa14e12; zgc:65776; zgc:77382", "protein_names_uniprotkb": "Vesicle-associated membrane protein-associated protein A", "protein_names_refseq": "vesicle-associated membrane protein-associated protein A isoform 1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "16109975;29879376;30286167", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC065663.1, SRR32588720.582583.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476744, SAMEA4476748 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On Feb 22, 2004 this sequence version replaced NP_956212.1., [RefSeq]; Endoplasmic reticulum (ER)-anchored protein that mediates the formation of contact sites between the ER and endosomes via interaction with FFAT motif-containing proteins such as STARD3 or WDR44. STARD3-VAPA interaction enables cholesterol transfer from the ER to endosomes. Via interaction with WDR44 participates in neosynthesized protein export. In addition, recruited to the plasma membrane through OSBPL3 binding. The OSBPL3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface. With OSBPL3, may regulate ER morphology. May play a role in vesicle trafficking., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0AC36K3U2-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TJ66-1", "uniprot_id": [ { "id": "A0AB32TJ66_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TJ66", "type": "external" } ], "mass": 72124.0, "length": 643, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC566482", "organism": "Zebrafish", "refseq_name": "uncharacterized LOC566482", "refseq_ac": [ { "id": "NP_001427671", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001427671", "type": "external" } ], "gene_names_uniprotkb": "LOC566482", "gene_names_refseq": "LOC566482", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "uncharacterized LOC566482", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.19850867.1, SRR32588728.46243062.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN18715719, SAMN18715720 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On May 28, 2025 this sequence version replaced XP_068073542.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32TJ66-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TQB6-1", "uniprot_id": [ { "id": "A0AB32TQB6_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TQB6", "type": "external" } ], "mass": 55161.0, "length": 471, "protein_name": "Uncharacterized protein isoform X1", "gene_name": "fi29h02; zgc:162958", "organism": "Zebrafish", "refseq_name": "uncharacterized protein isoform X1", "refseq_ac": [ { "id": "XP_073801723", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073801723", "type": "external" } ], "gene_names_uniprotkb": "fi29h02; zgc:162958; fi29h02; wu:fi29h02; zgc:162958", "gene_names_refseq": "fi29h02; wu:fi29h02; zgc:162958", "protein_names_uniprotkb": "Uncharacterized protein isoform X1", "protein_names_refseq": "uncharacterized protein isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58J5G1;A0AC58J5G6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32TQB6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TM09-1", "uniprot_id": [ { "id": "A0AB32TM09_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TM09", "type": "external" } ], "mass": 45927.0, "length": 404, "protein_name": "Uncharacterized protein isoform X1", "gene_name": "LOC103910819", "organism": "Zebrafish", "refseq_name": "uncharacterized protein isoform X1", "refseq_ac": [ { "id": "XP_068076905", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068076905", "type": "external" } ], "gene_names_uniprotkb": "LOC103910819", "gene_names_refseq": "LOC103910819", "protein_names_uniprotkb": "Uncharacterized protein isoform X1", "protein_names_refseq": "uncharacterized protein isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068076905.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32TM09-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36HI11-1", "uniprot_id": [ { "id": "A0AC36HI11_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36HI11", "type": "external" } ], "mass": 45153.0, "length": 412, "protein_name": "WW domain-binding protein 4", "gene_name": "wbp4", "organism": "Zebrafish", "refseq_name": "WW domain-binding protein 4", "refseq_ac": [ { "id": "NP_001018530", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018530", "type": "external" } ], "gene_names_uniprotkb": "wbp4; zgc:112384", "gene_names_refseq": "wbp4; zgc:112384", "protein_names_uniprotkb": "WW domain-binding protein 4", "protein_names_refseq": "WW domain-binding protein 4", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "26469318;27189481;31680844", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC095798.1, SRR26395062.956581.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On Jun 11, 2025 this sequence version replaced NP_001018530.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0AC36HI11-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TPV8-1", "uniprot_id": [ { "id": "A0AB32TPV8_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TPV8", "type": "external" } ], "mass": 87111.0, "length": 768, "protein_name": "Uncharacterized protein isoform X1", "gene_name": "zbedx", "organism": "Zebrafish", "refseq_name": "uncharacterized protein isoform X1", "refseq_ac": [ { "id": "XP_068077866", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068077866", "type": "external" } ], "gene_names_uniprotkb": "zbedx; fc12g06; wu:fb98h02; wu:fc12g06; zgc:161969", "gene_names_refseq": "fc12g06; wu:fb98h02; wu:fc12g06; zbedx; zgc:161969", "protein_names_uniprotkb": "Uncharacterized protein isoform X1", "protein_names_refseq": "uncharacterized protein isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:569044)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "25556858;26469318;27189481;36672921", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068077866.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0AB32TPV8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TWV7-1", "uniprot_id": [ { "id": "A0AB32TWV7_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TWV7", "type": "external" } ], "mass": 36374.0, "length": 327, "protein_name": "Novel immune-type receptor 1n isoform X1", "gene_name": "nitr1o", "organism": "Zebrafish", "refseq_name": "novel immune-type receptor 1n isoform X1", "refseq_ac": [ { "id": "XP_068078253", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068078253", "type": "external" } ], "gene_names_uniprotkb": "nitr1o; l04c06; nitr1.23; nitr1.44; nitr1.8; nitr1n; nitr1o_3; nitr1; si:busm1-263j20.7; si:dz105l16.8; si:dz263j20.7; wu:fl04c06; zgc:123076", "gene_names_refseq": "l04c06; nitr1.23; nitr1.44; nitr1.8; nitr1n; nitr1o_3; nitr1; si:busm1-263j20.7; si:dz105l16.8; si:dz263j20.7; wu:fl04c06; zgc:123076", "protein_names_uniprotkb": "Novel immune-type receptor 1n isoform X1", "protein_names_refseq": "novel immune-type receptor 1n isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068078253.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32TWV7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FXY5-1", "uniprot_id": [ { "id": "A0AC58FXY5_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FXY5", "type": "external" } ], "mass": 38793.0, "length": 344, "protein_name": "Novel immune-type receptor 1a isoform X1", "gene_name": "nitr1a", "organism": "Zebrafish", "refseq_name": "novel immune-type receptor 1a isoform X1", "refseq_ac": [ { "id": "XP_073762198", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073762198", "type": "external" } ], "gene_names_uniprotkb": "nitr1a; SI:dZ169I8.3; nitr1.18; nitr1.19; nitr1.30; nitr1.60; nitr1.64; nitr1a_1; nitr1a_2; nitr1; si:dz186f8.4", "gene_names_refseq": "SI:dZ169I8.3; nitr1.18; nitr1.19; nitr1.30; nitr1.60; nitr1.64; nitr1a_1; nitr1a_2; nitr1a; nitr1; si:dz186f8.4", "protein_names_uniprotkb": "Novel immune-type receptor 1a isoform X1", "protein_names_refseq": "novel immune-type receptor 1a isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58FXY5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32THU4-1", "uniprot_id": [ { "id": "A0AB32THU4_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32THU4", "type": "external" } ], "mass": 97543.0, "length": 885, "protein_name": "NF-X1-type zinc finger protein NFXL1", "gene_name": "nfxl1", "organism": "Zebrafish", "refseq_name": "NF-X1-type zinc finger protein NFXL1", "refseq_ac": [ { "id": "XP_068073062", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073062", "type": "external" } ], "gene_names_uniprotkb": "nfxl1", "gene_names_refseq": "nfxl1", "protein_names_uniprotkb": "NF-X1-type zinc finger protein NFXL1", "protein_names_refseq": "NF-X1-type zinc finger protein NFXL1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068073062.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32THU4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TIH5-1", "uniprot_id": [ { "id": "A0AB32TIH5_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TIH5", "type": "external" } ], "mass": 72846.0, "length": 647, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC561456", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_068075138", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068075138", "type": "external" } ], "gene_names_uniprotkb": "LOC561456", "gene_names_refseq": "LOC561456", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068075138.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32TIH5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TKG0-1", "uniprot_id": [ { "id": "A0AB32TKG0_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TKG0", "type": "external" } ], "mass": 31751.0, "length": 279, "protein_name": "Uncharacterized protein", "gene_name": "LOC137488533", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_068075038", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068075038", "type": "external" } ], "gene_names_uniprotkb": "LOC137488533", "gene_names_refseq": "LOC137488533", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068075038.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32TKG0-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TKU8-1", "uniprot_id": [ { "id": "A0AB32TKU8_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TKU8", "type": "external" } ], "mass": 16087.0, "length": 142, "protein_name": "E3 ubiquitin-protein ligase RBBP6-like", "gene_name": "LOC100005157", "organism": "Zebrafish", "refseq_name": "E3 ubiquitin-protein ligase RBBP6-like", "refseq_ac": [ { "id": "XP_068075530", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068075530", "type": "external" } ], "gene_names_uniprotkb": "LOC100005157", "gene_names_refseq": "LOC100005157", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RBBP6-like", "protein_names_refseq": "E3 ubiquitin-protein ligase RBBP6-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068075530.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32TKU8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TLA0-1", "uniprot_id": [ { "id": "A0AB32TLA0_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TLA0", "type": "external" } ], "mass": 47585.0, "length": 411, "protein_name": "Uncharacterized protein", "gene_name": "LOC100333266", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_073800012", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073800012", "type": "external" } ], "gene_names_uniprotkb": "LOC100333266", "gene_names_refseq": "LOC100333266", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58J0K0;A0AC58J0K3;A0AC58J0K6;A0AC58J0K7;A0AC58J0K9;A0AC58J0L4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32TLA0-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TSG7-1", "uniprot_id": [ { "id": "A0AB32TSG7_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TSG7", "type": "external" } ], "mass": 127669.0, "length": 1123, "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like", "gene_name": "LOC137491079", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC137491079", "gene_names_refseq": "", "protein_names_uniprotkb": "NACHT, LRR and PYD domains-containing protein 3-like", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32TSG7-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TUG9-1", "uniprot_id": [ { "id": "A0AB32TUG9_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TUG9", "type": "external" } ], "mass": 100474.0, "length": 902, "protein_name": "DNA polymerase kappa", "gene_name": "polk", "organism": "Zebrafish", "refseq_name": "DNA polymerase kappa", "refseq_ac": [ { "id": "XP_073807486", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073807486", "type": "external" } ], "gene_names_uniprotkb": "polk", "gene_names_refseq": "polk", "protein_names_uniprotkb": "DNA polymerase kappa; 2.7.7.7; DINB protein", "protein_names_refseq": "DNA polymerase kappa", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3'-5' proofreading exonuclease activity. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58JLW5", "ec_number_list": [ { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.31", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.7.102", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.102", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "4.2.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.-", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32TUG9-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TVV9-1", "uniprot_id": [ { "id": "A0AB32TVV9_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TVV9", "type": "external" } ], "mass": 27664.0, "length": 243, "protein_name": "Microfibril-associated glycoprotein 4-like", "gene_name": "LOC108179162", "organism": "Zebrafish", "refseq_name": "microfibril-associated glycoprotein 4-like", "refseq_ac": [ { "id": "XP_068076992", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068076992", "type": "external" } ], "gene_names_uniprotkb": "LOC108179162", "gene_names_refseq": "LOC108179162", "protein_names_uniprotkb": "Microfibril-associated glycoprotein 4-like", "protein_names_refseq": "microfibril-associated glycoprotein 4-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58G5I1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32TVV9-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TVX4-1", "uniprot_id": [ { "id": "A0AB32TVX4_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TVX4", "type": "external" } ], "mass": 60107.0, "length": 514, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC137490007", "organism": "Zebrafish", "refseq_name": "serine/threonine-protein kinase pim-1", "refseq_ac": [ { "id": "XP_068077007", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068077007", "type": "external" } ], "gene_names_uniprotkb": "LOC137490007", "gene_names_refseq": "LOC137490007", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase pim-1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068077007.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "GO:0016301 kinase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32TVX4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TW98-1", "uniprot_id": [ { "id": "A0AB32TW98_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TW98", "type": "external" } ], "mass": 34403.0, "length": 290, "protein_name": "Uncharacterized protein isoform X1", "gene_name": "LOC137490369", "organism": "Zebrafish", "refseq_name": "uncharacterized protein isoform X1", "refseq_ac": [ { "id": "XP_068080043", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068080043", "type": "external" } ], "gene_names_uniprotkb": "LOC137490369", "gene_names_refseq": "LOC137490369", "protein_names_uniprotkb": "Uncharacterized protein isoform X1", "protein_names_refseq": "uncharacterized protein isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068080043.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32TW98-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TX41-1", "uniprot_id": [ { "id": "A0AB32TX41_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TX41", "type": "external" } ], "mass": 65478.0, "length": 568, "protein_name": "Sialate:O-sulfotransferase 1", "gene_name": "wscd1b", "organism": "Zebrafish", "refseq_name": "sialate:O-sulfotransferase 1", "refseq_ac": [ { "id": "XP_073771201", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073771201", "type": "external" } ], "gene_names_uniprotkb": "wscd1b", "gene_names_refseq": "wscd1b", "protein_names_uniprotkb": "Sialate:O-sulfotransferase 1", "protein_names_refseq": "sialate:O-sulfotransferase 1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58GN87;A0AC58GN91", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32TX41-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TY47-1", "uniprot_id": [ { "id": "A0AB32TY47_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TY47", "type": "external" } ], "mass": 126241.0, "length": 1125, "protein_name": "DENN domain-containing protein 2B", "gene_name": "dennd2b", "organism": "Zebrafish", "refseq_name": "DENN domain-containing protein 2B", "refseq_ac": [ { "id": "NP_001002327", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002327", "type": "external" } ], "gene_names_uniprotkb": "dennd2b; si:ch211-208c6.1; st5; wu:fc11b09; zgc:91902", "gene_names_refseq": "dennd2b; si:ch211-208c6.1; st5; wu:fc11b09; zgc:91902", "protein_names_uniprotkb": "DENN domain-containing protein 2B", "protein_names_refseq": "DENN domain-containing protein 2B; suppression of tumorigenicity 5", "tax_id": 7955, "disease": "", "pathway": " (dre:323827)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15753045;16109975;25630924;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC076471.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505375, SAMEA3505379 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC076471.1., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0AB32TY47-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32TZZ0-1", "uniprot_id": [ { "id": "A0AB32TZZ0_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32TZZ0", "type": "external" } ], "mass": 110227.0, "length": 1006, "protein_name": "Protein kinase domain-containing protein", "gene_name": "LOC137490420", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_068080409", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068080409", "type": "external" } ], "gene_names_uniprotkb": "LOC137490420", "gene_names_refseq": "LOC137490420", "protein_names_uniprotkb": "Protein kinase domain-containing protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068080409.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32TZZ0-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32U0U0-1", "uniprot_id": [ { "id": "A0AB32U0U0_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32U0U0", "type": "external" } ], "mass": 25849.0, "length": 244, "protein_name": "L-xylulose reductase isoform X1", "gene_name": "dcxr", "organism": "Zebrafish", "refseq_name": "L-xylulose reductase", "refseq_ac": [ { "id": "NP_001017619", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017619", "type": "external" } ], "gene_names_uniprotkb": "dcxr; wu:fa12f09; zgc:111977", "gene_names_refseq": "dcxr; wu:fa12f09; zgc:111977", "protein_names_uniprotkb": "L-xylulose reductase isoform X1", "protein_names_refseq": "L-xylulose reductase", "tax_id": 7955, "disease": "pentosuria (Disease Ontology:DOID:0111258)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395028.394119.1, SRR26395012.80060.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505373 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1. On or before Jul 18, 2025 this sequence version replaced XP_005156041.2, NP_001017619.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58GVH2;A0AC58GVH4;A0AC58GVI5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32U0U0-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32U1I4-1", "uniprot_id": [ { "id": "A0AB32U1I4_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32U1I4", "type": "external" } ], "mass": 49613.0, "length": 438, "protein_name": "Protein eva-1 homolog C isoform X1", "gene_name": "eva1c", "organism": "Zebrafish", "refseq_name": "protein eva-1 homolog C isoform X1", "refseq_ac": [ { "id": "XP_068079936", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068079936", "type": "external" } ], "gene_names_uniprotkb": "eva1c", "gene_names_refseq": "eva1c", "protein_names_uniprotkb": "Protein eva-1 homolog C isoform X1", "protein_names_refseq": "protein eva-1 homolog C isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068079936.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32U1I4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AB32U3S8-1", "uniprot_id": [ { "id": "A0AB32U3S8_DANRE", "url": "https://www.uniprot.org/uniprot/A0AB32U3S8", "type": "external" } ], "mass": 19476.0, "length": 174, "protein_name": "E3 ubiquitin-protein ligase RBBP6-like isoform X1", "gene_name": "LOC110438888", "organism": "Zebrafish", "refseq_name": "E3 ubiquitin-protein ligase RBBP6-like isoform X1", "refseq_ac": [ { "id": "XP_068080564", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068080564", "type": "external" } ], "gene_names_uniprotkb": "LOC110438888", "gene_names_refseq": "LOC110438888", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RBBP6-like isoform X1", "protein_names_refseq": "E3 ubiquitin-protein ligase RBBP6-like isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068080564.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AB32U3S8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36H5Y0-1", "uniprot_id": [ { "id": "A0AC36H5Y0_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36H5Y0", "type": "external" } ], "mass": 47726.0, "length": 416, "protein_name": "Uncharacterized protein LOC445188", "gene_name": "zgc:101048", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC445188", "refseq_ac": [ { "id": "NP_001003582", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003582", "type": "external" } ], "gene_names_uniprotkb": "zgc:101048", "gene_names_refseq": "zgc:101048", "protein_names_uniprotkb": "Uncharacterized protein LOC445188", "protein_names_refseq": "uncharacterized protein LOC445188", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "12477932", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC077115.1, SRR26395012.1648409.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505380 [ECO:0006172] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from BC077115.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0AC36H5Y0-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36H8J3-1", "uniprot_id": [ { "id": "A0AC36H8J3_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36H8J3", "type": "external" } ], "mass": 37615.0, "length": 333, "protein_name": "Novel immune-type receptor 3c isoform X1; Novel immune-type receptor 3c precursor", "gene_name": "nitr3c", "organism": "Zebrafish", "refseq_name": "novel immune-type receptor 3c precursor", "refseq_ac": [ { "id": "NP_001007203", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007203", "type": "external" } ], "gene_names_uniprotkb": "nitr3c; nitr3.5; nitr3.8; nitr3c_2; nitr; si:busm1-221h6.2; si:dz221h6.2; zgc:109830", "gene_names_refseq": "nitr3.5; nitr3.8; nitr3c_2; nitr3c; nitr; si:busm1-221h6.2; si:dz221h6.2; zgc:109830", "protein_names_uniprotkb": "Novel immune-type receptor 3c isoform X1; Novel immune-type receptor 3c precursor", "protein_names_refseq": "novel immune-type receptor 3c precursor", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "15496470;18565225;20012603", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN18715719 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL591420.5. On Feb 21, 2008 this sequence version replaced XP_001335044.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58G0S2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0AC36H8J3-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36HBC9-1", "uniprot_id": [ { "id": "A0AC36HBC9_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36HBC9", "type": "external" } ], "mass": 38085.0, "length": 335, "protein_name": "S100P-binding protein", "gene_name": "kop", "organism": "Zebrafish", "refseq_name": "S100P-binding protein", "refseq_ac": [ { "id": "NP_001007788", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007788", "type": "external" } ], "gene_names_uniprotkb": "kop; zgc:123051", "gene_names_refseq": "kop; zgc:123051", "protein_names_uniprotkb": "S100P-binding protein", "protein_names_refseq": "S100P-binding protein; kop; nucleoprotein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 10, "publication_id_list": "16129886;17084355;18507824;20010816;23535913;27070582;27373161;33106478;33574063;34617657", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AY572416.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898399, SAMEA898400 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY572416.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "A0AC36HBC9-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36HGX9-1", "uniprot_id": [ { "id": "A0AC36HGX9_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36HGX9", "type": "external" } ], "mass": 20539.0, "length": 181, "protein_name": "ADP-ribosylation factor", "gene_name": "zgc:110286", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC550265", "refseq_ac": [ { "id": "NP_001017602", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017602", "type": "external" } ], "gene_names_uniprotkb": "zgc:110286; si:ch1073-165f9.1", "gene_names_refseq": "si:ch1073-165f9.1; zgc:110286", "protein_names_uniprotkb": "ADP-ribosylation factor", "protein_names_refseq": "uncharacterized protein LOC550265", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23000284", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC092850.1, CO801665.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505372, SAMEA3505374 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1 and EH498607.1. On or before Aug 27, 2018 this sequence version replaced XP_009304579.3, XP_005168122.1, XP_699574.1., [RefSeq]; GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003925 G protein activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0AC36HGX9-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36HNQ2-1", "uniprot_id": [ { "id": "A0AC36HNQ2_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36HNQ2", "type": "external" } ], "mass": 60091.0, "length": 531, "protein_name": "UDP glucuronosyltransferase 5 family, polypeptide B6 precursor", "gene_name": "ugt5b6", "organism": "Zebrafish", "refseq_name": "UDP glucuronosyltransferase 5 family, polypeptide B6 precursor", "refseq_ac": [ { "id": "NP_001035435", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035435", "type": "external" } ], "gene_names_uniprotkb": "ugt5b6; zgc:136978", "gene_names_refseq": "ugt5b6; zgc:136978", "protein_names_uniprotkb": "UDP glucuronosyltransferase 5 family, polypeptide B6 precursor", "protein_names_refseq": "UDP glucuronosyltransferase 5 family, polypeptide B6 precursor", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "20161780", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC115353.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN18715701, SAMN18715702 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC115353.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0AC36HNQ2-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36IFG7-1", "uniprot_id": [ { "id": "A0AC36IFG7_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36IFG7", "type": "external" } ], "mass": 56732.0, "length": 499, "protein_name": "Cytochrome P450 2AA7", "gene_name": "cyp2aa7", "organism": "Zebrafish", "refseq_name": "cytochrome P450 2AA7", "refseq_ac": [ { "id": "NP_001103192", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103192", "type": "external" } ], "gene_names_uniprotkb": "cyp2aa7; zgc:171947", "gene_names_refseq": "cyp2aa7; zgc:171947", "protein_names_uniprotkb": "Cytochrome P450 2AA7", "protein_names_refseq": "cytochrome P450 2AA7", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 9, "publication_id_list": "21087487;21116621;23711412;23726801;23922661;26469318;28411468;29725939;33392193", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC152008.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC152008.1. On Oct 5, 2007 this sequence version replaced XP_001330986.1., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0AC36IFG7-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36II49-1", "uniprot_id": [ { "id": "A0AC36II49_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36II49", "type": "external" } ], "mass": 47216.0, "length": 409, "protein_name": "Sphingomyelin synthase-related protein 1", "gene_name": "zgc:175139", "organism": "Zebrafish", "refseq_name": "Sphingomyelin synthase-related protein 1-like", "refseq_ac": [ { "id": "NP_001108374", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108374", "type": "external" } ], "gene_names_uniprotkb": "zgc:175139", "gene_names_refseq": "samd8b; zgc:175139", "protein_names_uniprotkb": "Sphingomyelin synthase-related protein 1; 3.1.4.62; Ceramide phosphoethanolamine synthase; Phosphatidylethanolamine Phospholipase C; Sterile alpha motif domain-containing protein 8", "protein_names_refseq": "Sphingomyelin synthase-related protein 1-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "12477932", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01046672.1, GDQH01004603.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505372, SAMEA3505373 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1. On Jun 26, 2025 this sequence version replaced XP_073773392.1., [RefSeq]; Has phospholipase C (PLC) activity. Shows specificity for phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE), hydrolyzing PE to produce phosphoethanolamine and diacylglycerol (1,2-diacyl-sn-glycerol, DAG). This reaction might act as a regulatory switch to activate serine palmitoyltransferase (SPT) and promote sphingolipid metabolism. Can also function as a ceramide phosphoethanolamine (N-acylsphingoid 1-phosphoethanolamine, CPE) synthase when intracellular ceramide levels are elevated. Binds the headgroup from PE, which is smaller and more hydrophilic than the phosphocholine headgroup transferred in the canonical sphingomyelin synthesis (SMS) reaction by SMS1 or SMS2, and transfers it on to the primary hydroxyl of a ceramide in the lumen of the endoplasmic reticulum. Plays a role as a ceramide sensor, helping to regulate ceramide homeostasis in the endoplasmic reticulum, which is critical for maintaining the integrity of the early secretory pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58GUI3", "ec_number_list": [ { "id": "2.7.8.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.27", "type": "external" }, { "id": "3.1.4.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.62", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0AC36II49-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36IS99-1", "uniprot_id": [ { "id": "A0AC36IS99_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36IS99", "type": "external" } ], "mass": 33862.0, "length": 306, "protein_name": "Actinodin4 precursor", "gene_name": "and4", "organism": "Zebrafish", "refseq_name": "actinodin4 precursor", "refseq_ac": [ { "id": "NP_001129716", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129716", "type": "external" } ], "gene_names_uniprotkb": "and4; zgc:172167", "gene_names_refseq": "and4; zgc:172167", "protein_names_uniprotkb": "Actinodin4 precursor", "protein_names_refseq": "actinodin4 precursor", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 7, "publication_id_list": "20574421;23598338;23924636;25504979;28760345;33105605;35867745", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC167446.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC167446.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0AC36IS99-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36JWA4-1", "uniprot_id": [ { "id": "A0AC36JWA4_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36JWA4", "type": "external" } ], "mass": 48035.0, "length": 426, "protein_name": "Transcriptional enhancer factor TEF-1", "gene_name": "tead1b", "organism": "Zebrafish", "refseq_name": "transcriptional enhancer factor TEF-1", "refseq_ac": [ { "id": "NP_001422764", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422764", "type": "external" } ], "gene_names_uniprotkb": "tead1b; tead1", "gene_names_refseq": "tead1b; tead1", "protein_names_uniprotkb": "Transcriptional enhancer factor TEF-1", "protein_names_refseq": "TEA domain family member 1 (SV40 transcriptional enhancer factor); transcriptional enhancer factor TEF-1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "18850331;26469318;27935819;34162866;37628618", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01019927.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476737, SAMEA4476738 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## non-AUG initiation codon :: inferred from conservation ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Jan 14, 2025 this sequence version replaced XP_009301864.1., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0AC36JWA4-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36JWE5-1", "uniprot_id": [ { "id": "A0AC36JWE5_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36JWE5", "type": "external" } ], "mass": 56167.0, "length": 511, "protein_name": "NF-kappa-B inhibitor delta", "gene_name": "nfkbid", "organism": "Zebrafish", "refseq_name": "NF-kappa-B inhibitor delta", "refseq_ac": [ { "id": "NP_001422814", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422814", "type": "external" } ], "gene_names_uniprotkb": "nfkbid", "gene_names_refseq": "nfkbid", "protein_names_uniprotkb": "NF-kappa-B inhibitor delta", "protein_names_refseq": "NF-kappa-B inhibitor delta; zmp:0000000814", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "26469318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588718.37942980.1, SRR32588729.8645345.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN18715719 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## non-AUG initiation codon :: inferred from conservation ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Jan 15, 2025 this sequence version replaced XP_068070225.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0AC36JWE5-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36JWH2-1", "uniprot_id": [ { "id": "A0AC36JWH2_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36JWH2", "type": "external" } ], "mass": 48163.0, "length": 427, "protein_name": "Transcriptional enhancer factor TEF-5", "gene_name": "tead3a", "organism": "Zebrafish", "refseq_name": "transcriptional enhancer factor TEF-5", "refseq_ac": [ { "id": "NP_001422820", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422820", "type": "external" } ], "gene_names_uniprotkb": "tead3a; cb882; si:ch211-194j14.2; tead3", "gene_names_refseq": "cb882; si:ch211-194j14.2; tead3a; tead3", "protein_names_uniprotkb": "Transcriptional enhancer factor TEF-5", "protein_names_refseq": "transcriptional enhancer factor TEF-5", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 9, "publication_id_list": "17916448;26161877;26469318;27189481;27935819;31502954;31513014;34162866;35111746", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588728.2422140.1, SRR26395015.181168.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505388, SAMEA4476743 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## non-AUG initiation codon :: inferred from conservation ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Jan 15, 2025 this sequence version replaced XP_017209206.1., [RefSeq]; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis., [UniProtKB, UniProtKB]; Vgl-2b is expressed transiently in nascent notochord and in muscle fibres during somitogenesis.(vgl-2b) Muscle cells also express a TEAD-3 homologue, a possible partner of Vgl-2b, during myoblast differentiation and early fibre assembly., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0AC36JWH2-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36JWM2-1", "uniprot_id": [ { "id": "A0AC36JWM2_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36JWM2", "type": "external" } ], "mass": 46398.0, "length": 410, "protein_name": "Armadillo like helical domain containing 1; Armadillo-like helical domain containing protein 1 isoform X1", "gene_name": "armh1", "organism": "Zebrafish", "refseq_name": "armadillo-like helical domain containing protein 1", "refseq_ac": [ { "id": "NP_001423531", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001423531", "type": "external" } ], "gene_names_uniprotkb": "armh1; si:ch211-241d21.5", "gene_names_refseq": "armh1; si:ch211-241d21.5", "protein_names_uniprotkb": "Armadillo like helical domain containing 1; Armadillo-like helical domain containing protein 1 isoform X1", "protein_names_refseq": "armadillo-like helical domain containing protein 1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "12618376;21873635", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: ERR5059480.3069787.1, SRR32588732.1641347.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58G5L4;A0AC58G5L6;A0AC58G5M1;A0AC58G5M7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0AC36JWM2-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36JYA5-1", "uniprot_id": [ { "id": "A0AC36JYA5_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36JYA5", "type": "external" } ], "mass": 18258.0, "length": 168, "protein_name": "Transmembrane protein 88B", "gene_name": "tmem88bl", "organism": "Zebrafish", "refseq_name": "transmembrane protein 88B", "refseq_ac": [ { "id": "NP_001420657", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001420657", "type": "external" } ], "gene_names_uniprotkb": "tmem88bl", "gene_names_refseq": "tmem88bl", "protein_names_uniprotkb": "Transmembrane protein 88B", "protein_names_refseq": "transmembrane protein 88 bl; transmembrane protein 88B", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.10200670.1, SRR32588719.13108940.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505374, SAMEA3505388 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC36JYA5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36JYB1-1", "uniprot_id": [ { "id": "A0AC36JYB1_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36JYB1", "type": "external" } ], "mass": 59159.0, "length": 526, "protein_name": "Adenine DNA glycosylase", "gene_name": "mutyh", "organism": "Zebrafish", "refseq_name": "adenine DNA glycosylase", "refseq_ac": [ { "id": "NP_001423532", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001423532", "type": "external" } ], "gene_names_uniprotkb": "mutyh; si:ch211-241d21.4", "gene_names_refseq": "mutyh; si:ch211-241d21.4", "protein_names_uniprotkb": "Adenine DNA glycosylase; 3.2.2.31", "protein_names_refseq": "adenine DNA glycosylase; mutY homolog", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "34390914", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01019031.1, GDQQ01024417.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1., [RefSeq]; Adenine glycosylase active on G-A mispairs., [UniProtKB, UniProtKB]; Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000701 purine-specific mismatch base pair DNA N-glycosylase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0AC36JYB1-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36K4V6-1", "uniprot_id": [ { "id": "A0AC36K4V6_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36K4V6", "type": "external" } ], "mass": 45747.0, "length": 412, "protein_name": "G-protein coupled receptor 143", "gene_name": "gpr143", "organism": "Zebrafish", "refseq_name": "G-protein coupled receptor 143", "refseq_ac": [ { "id": "NP_957116", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957116", "type": "external" } ], "gene_names_uniprotkb": "gpr143; zgc:65915; zgc:77322", "gene_names_refseq": "gpr143; zgc:65915; zgc:77322", "protein_names_uniprotkb": "G-protein coupled receptor 143", "protein_names_refseq": "G-protein coupled receptor 143", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 8, "publication_id_list": "16109975;20034102;25690007;26469318;27189481;31138706;34397384;37201426", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC065340.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC065340.1. On Jul 18, 2004 this sequence version replaced NP_957116.1., [RefSeq]; Melanosome number, shape and movement in the zebrafish retinal pigment epithelium by OA1 and PMEL., [RefSeq, PubMed]; Receptor for tyrosine, L-DOPA and dopamine. After binding to L-DOPA, stimulates Ca(2+) influx into the cytoplasm, increases secretion of the neurotrophic factor SERPINF1 and relocalizes beta arrestin at the plasma membrane; this ligand-dependent signaling occurs through a G(q)-mediated pathway in melanocytic cells. Its activity is mediated by G proteins which activate the phosphoinositide signaling pathway. Also plays a role as an intracellular G protein-coupled receptor involved in melanosome biogenesis, organization and transport., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0AC36K4V6-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC36K5Z9-1", "uniprot_id": [ { "id": "A0AC36K5Z9_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC36K5Z9", "type": "external" } ], "mass": 34333.0, "length": 306, "protein_name": "3.5.1.121; Protein N-terminal asparagine amidohydrolase", "gene_name": "ntan1", "organism": "Zebrafish", "refseq_name": "protein N-terminal asparagine amidohydrolase", "refseq_ac": [ { "id": "NP_957145", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957145", "type": "external" } ], "gene_names_uniprotkb": "ntan1; si:dkey-264o13.5; zgc:77869", "gene_names_refseq": "ntan1; si:dkey-264o13.5; zgc:77869", "protein_names_uniprotkb": "3.5.1.121; Protein N-terminal asparagine amidohydrolase", "protein_names_refseq": "protein N-terminal asparagine amidohydrolase", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "12477932;21873635", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC062529.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505389, SAMEA3505391 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC062529.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008418 protein-N-terminal asparagine amidohydrolase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0AC36K5Z9-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC45FQJ1-1", "uniprot_id": [ { "id": "A0AC45FQJ1_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC45FQJ1", "type": "external" } ], "mass": 18794.0, "length": 175, "protein_name": "Uncharacterized protein trdc", "gene_name": "trdc", "organism": "Zebrafish", "refseq_name": "uncharacterized protein trdc", "refseq_ac": [ { "id": "XP_021323330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323330", "type": "external" } ], "gene_names_uniprotkb": "trdc", "gene_names_refseq": "trdc", "protein_names_uniprotkb": "Uncharacterized protein trdc", "protein_names_refseq": "uncharacterized protein trdc", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC45FQJ1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC45FXK3-1", "uniprot_id": [ { "id": "A0AC45FXK3_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC45FXK3", "type": "external" } ], "mass": 237530.0, "length": 2151, "protein_name": "Basement membrane-specific heparan sulfate proteoglycan core protein isoform X1", "gene_name": "si:cabz01036006.1", "organism": "Zebrafish", "refseq_name": "basement membrane-specific heparan sulfate proteoglycan core protein isoform X1", "refseq_ac": [ { "id": "XP_021333347", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333347", "type": "external" } ], "gene_names_uniprotkb": "si:cabz01036006.1", "gene_names_refseq": "si:cabz01036006.1", "protein_names_uniprotkb": "Basement membrane-specific heparan sulfate proteoglycan core protein isoform X1", "protein_names_refseq": "basement membrane-specific heparan sulfate proteoglycan core protein isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021333347.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC45FXK3-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FWC7-1", "uniprot_id": [ { "id": "A0AC58FWC7_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FWC7", "type": "external" } ], "mass": 31911.0, "length": 282, "protein_name": "Uncharacterized protein", "gene_name": "LOC141375077", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_073761976", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073761976", "type": "external" } ], "gene_names_uniprotkb": "LOC141375077", "gene_names_refseq": "LOC141375077", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58FWC7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FWK5-1", "uniprot_id": [ { "id": "A0AC58FWK5_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FWK5", "type": "external" } ], "mass": 38115.0, "length": 328, "protein_name": "Tc1-like transposase DDE domain-containing protein", "gene_name": "LOC141375079", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_073761989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073761989", "type": "external" } ], "gene_names_uniprotkb": "LOC141375079", "gene_names_refseq": "LOC141375079", "protein_names_uniprotkb": "Tc1-like transposase DDE domain-containing protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by mRNA evidence. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. 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This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58FYZ2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58FYI8-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FYJ7-1", "uniprot_id": [ { "id": "A0AC58FYJ7_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FYJ7", "type": "external" } ], "mass": 25121.0, "length": 228, "protein_name": "Ankyrin repeat domain-containing protein 46 isoform X1", "gene_name": "ankrd46b", "organism": "Zebrafish", "refseq_name": "ankyrin repeat domain-containing protein 46", "refseq_ac": [ { "id": "NP_991159", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_991159", "type": "external" } ], "gene_names_uniprotkb": "ankrd46b; ankrd46; wu:fq41d11; zgc:109722", "gene_names_refseq": "ankrd46b; ankrd46; wu:fq41d11; zgc:109722", "protein_names_uniprotkb": "Ankyrin repeat domain-containing protein 46 isoform X1", "protein_names_refseq": "ankyrin repeat domain 46; ankyrin repeat domain-containing protein 46", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AY391435.1, EV755698.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476731 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY391435.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58FYJ7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FYN4-1", "uniprot_id": [ { "id": "A0AC58FYN4_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FYN4", "type": "external" } ], "mass": 98086.0, "length": 893, "protein_name": "Fc receptor-like protein 5 isoform X2", "gene_name": "LOC137495974", "organism": "Zebrafish", "refseq_name": "Fc receptor-like protein 5 precursor", "refseq_ac": [ { "id": "NP_001430376", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430376", "type": "external" } ], "gene_names_uniprotkb": "LOC137495974", "gene_names_refseq": "LOC137495974", "protein_names_uniprotkb": "Fc receptor-like protein 5 isoform X2", "protein_names_refseq": "Fc receptor-like protein 5 precursor", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.16227348.1 [ECO:0000332] RNAseq introns :: partial sample support SAMN18715711 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Sep 15, 2025 this sequence version replaced XP_073762656.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58FYN4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FYP7-1", "uniprot_id": [ { "id": "A0AC58FYP7_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FYP7", "type": "external" } ], "mass": 95334.0, "length": 869, "protein_name": "Uncharacterized protein isoform X1", "gene_name": "LOC141375099", "organism": "Zebrafish", "refseq_name": "uncharacterized protein isoform X1", "refseq_ac": [ { "id": "XP_073762664", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073762664", "type": "external" } ], "gene_names_uniprotkb": "LOC141375099", "gene_names_refseq": "LOC141375099", "protein_names_uniprotkb": "Uncharacterized protein isoform X1", "protein_names_refseq": "uncharacterized protein isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58FYP7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FYQ6-1", "uniprot_id": [ { "id": "A0AC58FYQ6_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FYQ6", "type": "external" } ], "mass": 55676.0, "length": 495, "protein_name": "Cytosolic beta-glucosidase isoform X1", "gene_name": "gba3", "organism": "Zebrafish", "refseq_name": "cytosolic beta-glucosidase isoform X1", "refseq_ac": [ { "id": "XP_073762669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073762669", "type": "external" } ], "gene_names_uniprotkb": "gba3; im:6912508; zgc:112375", "gene_names_refseq": "gba3; im:6912508; zgc:112375", "protein_names_uniprotkb": "Cytosolic beta-glucosidase isoform X1", "protein_names_refseq": "cytosolic beta-glucosidase isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58FYQ6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FZ34-1", "uniprot_id": [ { "id": "A0AC58FZ34_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FZ34", "type": "external" } ], "mass": 87264.0, "length": 784, "protein_name": "Cell adhesion molecule CEACAM5-like isoform X1", "gene_name": "si:dkey-27j5.8", "organism": "Zebrafish", "refseq_name": "cell adhesion molecule CEACAM5-like isoform X1", "refseq_ac": [ { "id": "XP_073762792", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073762792", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-27j5.8", "gene_names_refseq": "si:dkey-27j5.8", "protein_names_uniprotkb": "Cell adhesion molecule CEACAM5-like isoform X1", "protein_names_refseq": "cell adhesion molecule CEACAM5-like isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58FZ34-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FZ35-1", "uniprot_id": [ { "id": "A0AC58FZ35_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FZ35", "type": "external" } ], "mass": 93139.0, "length": 816, "protein_name": "C-type lectin domain-containing protein", "gene_name": "LOC141375100", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_073762786", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073762786", "type": "external" } ], "gene_names_uniprotkb": "LOC141375100", "gene_names_refseq": "LOC141375100", "protein_names_uniprotkb": "C-type lectin domain-containing protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58FZ44-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FZ58-1", "uniprot_id": [ { "id": "A0AC58FZ58_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FZ58", "type": "external" } ], "mass": 46631.0, "length": 421, "protein_name": "Serine (Or cysteine) peptidase inhibitor, clade H, member 2 isoform X1", "gene_name": "serpinh2", "organism": "Zebrafish", "refseq_name": "serine (or cysteine) peptidase inhibitor, clade H, member 2 isoform X1", "refseq_ac": [ { "id": "XP_073762675", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073762675", "type": "external" } ], "gene_names_uniprotkb": "serpinh2; zgc:113025", "gene_names_refseq": "serpinh2; zgc:113025", "protein_names_uniprotkb": "Serine (Or cysteine) peptidase inhibitor, clade H, member 2 isoform X1", "protein_names_refseq": "serine (or cysteine) peptidase inhibitor, clade H, member 2 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005525 GTP binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2I6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G0D6-1", "uniprot_id": [ { "id": "A0AC58G0D6_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G0D6", "type": "external" } ], "mass": 57406.0, "length": 508, "protein_name": "GTPase IMAP family member 8", "gene_name": "LOC100334176", "organism": "Zebrafish", "refseq_name": "GTPase IMAP family member 8 isoform X1", "refseq_ac": [ { "id": "XP_073763225", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763225", "type": "external" } ], "gene_names_uniprotkb": "LOC100334176", "gene_names_refseq": "LOC100334176", "protein_names_uniprotkb": "GTPase IMAP family member 8; Immune-associated nucleotide-binding protein 9", "protein_names_refseq": "GTPase IMAP family member 8 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100334176)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58G0M8", "ec_number_list": [], "go_molecular_function": "GO:0005525 GTP binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G0D6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G1P7-1", "uniprot_id": [ { "id": "A0AC58G1P7_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G1P7", "type": "external" } ], "mass": 127824.0, "length": 1164, "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "gene_name": "ppargc1a", "organism": "Zebrafish", "refseq_name": "peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1", "refseq_ac": [ { "id": "XP_073763663", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763663", "type": "external" } ], "gene_names_uniprotkb": "ppargc1a", "gene_names_refseq": "ppargc1a", "protein_names_uniprotkb": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "protein_names_refseq": "peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1", "tax_id": 7955, "disease": "congenital hypothyroidism (Disease Ontology:DOID:0050328); cardiomyopathy (Disease Ontology:DOID:0050700); renal fibrosis (Disease Ontology:DOID:0050855); colitis (Disease Ontology:DOID:0060180); abdominal obesity-metabolic syndrome (Disease Ontology:DOID:0060611); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); amblyopia (Disease Ontology:DOID:10376); Alzheimer's disease (Disease Ontology:DOID:10652); kidney failure (Disease Ontology:DOID:1074); age related macular degeneration (Disease Ontology:DOID:10871); amnestic disorder (Disease Ontology:DOID:10914); heart disease (Disease Ontology:DOID:114); sciatic neuropathy (Disease Ontology:DOID:11446); prediabetes syndrome (Disease Ontology:DOID:11716); nephrotic syndrome (Disease Ontology:DOID:1184); morbid obesity (Disease Ontology:DOID:11981); primary biliary cholangitis (Disease Ontology:DOID:12236); Huntington's disease (Disease Ontology:DOID:12858); cardiovascular system disease (Disease Ontology:DOID:1287); dilated cardiomyopathy (Disease Ontology:DOID:12930); Parkinson's disease (Disease Ontology:DOID:14330); malignant fibrous histiocytoma (Disease Ontology:DOID:1907); melanoma (Disease Ontology:DOID:1909); kidney cancer (Disease Ontology:DOID:263); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); placental insufficiency (Disease Ontology:DOID:3891); hyperglycemia (Disease Ontology:DOID:4195); macular degeneration (Disease Ontology:DOID:4448); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); hyperthyroidism (Disease Ontology:DOID:7998); diabetic retinopathy (Disease Ontology:DOID:8947); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:553418)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 37, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003712 transcription coregulator activity;GO:0003713 transcription coactivator activity", "go_cellular_component": "GO:0016605 PML body;GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0048511 rhythmic process;GO:0019646 aerobic electron transport chain;GO:0007519 skeletal muscle tissue development;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G1P7-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G051-1", "uniprot_id": [ { "id": "A0AC58G051_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G051", "type": "external" } ], "mass": 35820.0, "length": 327, "protein_name": "Brain-derived neurotrophic factor", "gene_name": "bdnf", "organism": "Zebrafish", "refseq_name": "neurotrophic factor BDNF precursor form isoform X1", "refseq_ac": [ { "id": "XP_073763149", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763149", "type": "external" } ], "gene_names_uniprotkb": "bdnf", "gene_names_refseq": "bdnf", "protein_names_uniprotkb": "Brain-derived neurotrophic factor; proBDNF", "protein_names_refseq": "neurotrophic factor BDNF precursor form isoform X1", "tax_id": 7955, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); obstructive sleep apnea (Disease Ontology:DOID:0050848); stroke (Disease Ontology:DOID:0051061); withdrawal disorder (Disease Ontology:DOID:0060001); autism spectrum disorder (Disease Ontology:DOID:0060041); congenital central hypoventilation syndrome (Disease Ontology:DOID:0060731); Parkinsonism (Disease Ontology:DOID:0080855); traumatic brain injury (Disease Ontology:DOID:0081292); keratoconus (Disease Ontology:DOID:10126); Alzheimer's disease (Disease Ontology:DOID:10652); primary open angle glaucoma (Disease Ontology:DOID:1070); amnestic disorder (Disease Ontology:DOID:10914); obsessive-compulsive disorder (Disease Ontology:DOID:10933); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); sciatic neuropathy (Disease Ontology:DOID:11446); trigeminal neuralgia (Disease Ontology:DOID:12098); acoustic neuroma (Disease Ontology:DOID:12689); Huntington's disease (Disease Ontology:DOID:12858); Sjogren's syndrome (Disease Ontology:DOID:12894); color blindness (Disease Ontology:DOID:13399); pulmonary sarcoidosis (Disease Ontology:DOID:13406); low tension glaucoma (Disease Ontology:DOID:13544); premature ejaculation (Disease Ontology:DOID:13709); Parkinson's disease (Disease Ontology:DOID:14330); hypothyroidism (Disease Ontology:DOID:1459); major depressive disorder (Disease Ontology:DOID:1470); urticaria (Disease Ontology:DOID:1555); cognitive disorder (Disease Ontology:DOID:1561); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); cystitis (Disease Ontology:DOID:1679); glaucoma (Disease Ontology:DOID:1686); status epilepticus (Disease Ontology:DOID:1824); anxiety disorder (Disease Ontology:DOID:2030); post-traumatic stress disorder (Disease Ontology:DOID:2055); transient cerebral ischemia (Disease Ontology:DOID:224); multiple sclerosis (Disease Ontology:DOID:2377); opiate dependence (Disease Ontology:DOID:2559); morphine dependence (Disease Ontology:DOID:2560); asthma (Disease Ontology:DOID:2841); interstitial lung disease (Disease Ontology:DOID:3082); atopic dermatitis (Disease Ontology:DOID:3310); mood disorder (Disease Ontology:DOID:3324); middle cerebral artery infarction (Disease Ontology:DOID:3525); pulmonary fibrosis (Disease Ontology:DOID:3770); systemic scleroderma (Disease Ontology:DOID:418); rhinitis (Disease Ontology:DOID:4483); borna disease (Disease Ontology:DOID:5154); intestinal disease (Disease Ontology:DOID:5295); acute stress disorder (Disease Ontology:DOID:6088); amphetamine abuse (Disease Ontology:DOID:670); retinal degeneration (Disease Ontology:DOID:8466); vascular dementia (Disease Ontology:DOID:8725); intermediate coronary syndrome (Disease Ontology:DOID:8805); diabetic retinopathy (Disease Ontology:DOID:8947); type 2 diabetes mellitus (Disease Ontology:DOID:9352); hypertensive encephalopathy (Disease Ontology:DOID:9427); bacterial meningitis (Disease Ontology:DOID:9470); cannabis abuse (Disease Ontology:DOID:9505); neovascular inflammatory vitreoretinopathy (Disease Ontology:DOID:9719); diabetic neuropathy (Disease Ontology:DOID:9743); irritable bowel syndrome (Disease Ontology:DOID:9778); alopecia (Disease Ontology:DOID:987); obesity (Disease Ontology:DOID:9970); cocaine dependence (Disease Ontology:DOID:9975); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (dre:58118)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12812528;15153250;16231865;19193881;20162349;38902941;38938421;38961588;39213521;39273418", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 67, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008083 growth factor activity;GO:0005163 nerve growth factor receptor binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0008021 synaptic vesicle", "go_biological_process": "GO:0099054 presynapse assembly;GO:0007420 brain development;GO:0007623 circadian rhythm;GO:0048512 circadian behavior;GO:0071542 dopaminergic neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "A0AC58G051-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2T7-1", "uniprot_id": [ { "id": "A0AC58G2T7_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2T7", "type": "external" } ], "mass": 142175.0, "length": 1289, "protein_name": "Fc receptor-like protein 5 isoform X1", "gene_name": "LOC108190752", "organism": "Zebrafish", "refseq_name": "Fc receptor-like protein 5 isoform X1", "refseq_ac": [ { "id": "XP_073764038", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764038", "type": "external" } ], "gene_names_uniprotkb": "LOC108190752", "gene_names_refseq": "LOC108190752", "protein_names_uniprotkb": "Fc receptor-like protein 5 isoform X1", "protein_names_refseq": "Fc receptor-like protein 5 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:108190752)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2F5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G1W1-1", "uniprot_id": [ { "id": "A0AC58G1W1_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G1W1", "type": "external" } ], "mass": 48074.0, "length": 424, "protein_name": "B-cell receptor CD22", "gene_name": "LOC100006752", "organism": "Zebrafish", "refseq_name": "B-cell receptor CD22 isoform X1", "refseq_ac": [ { "id": "XP_073763715", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763715", "type": "external" } ], "gene_names_uniprotkb": "LOC100006752", "gene_names_refseq": "LOC100006752", "protein_names_uniprotkb": "B-cell receptor CD22; Sialic acid-binding Ig-like lectin 2", "protein_names_refseq": "B-cell receptor CD22 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100006752)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Most highly expressed siglec (sialic acid-binding immunoglobulin-like lectin) on B-cells that plays a role in various aspects of B-cell biology including differentiation, antigen presentation, and trafficking to bone marrow. Binds to alpha 2,6-linked sialic acid residues of surface molecules such as CD22 itself, CD45 and IgM in a cis configuration. Can also bind to ligands on other cells as an adhesion molecule in a trans configuration. Acts as an inhibitory coreceptor on the surface of B-cells and inhibits B-cell receptor induced signaling, characterized by inhibition of the calcium mobilization and cellular activation. Mechanistically, the immunoreceptor tyrosine-based inhibitory motif domain is phosphorylated by the Src kinase LYN, which in turn leads to the recruitment of the protein tyrosine phosphatase 1/PTPN6, leading to the negative regulation of BCR signaling. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by mRNA evidence. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G167-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G007-1", "uniprot_id": [ { "id": "A0AC58G007_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G007", "type": "external" } ], "mass": 37727.0, "length": 341, "protein_name": "Haptoglobin isoform X1", "gene_name": "hp", "organism": "Zebrafish", "refseq_name": "haptoglobin isoform X1", "refseq_ac": [ { "id": "XP_073762991", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073762991", "type": "external" } ], "gene_names_uniprotkb": "hp; 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chronic kidney disease (Disease Ontology:DOID:784); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); pulmonary embolism (Disease Ontology:DOID:9477); type 1 diabetes mellitus (Disease Ontology:DOID:9744); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:566096)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "16537503;16630661;16631158;21641930;22805612;28582574;28625747;29980668;34771727;35864190", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by mRNA evidence. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0000145 exocyst", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0090522 vesicle tethering involved in exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0AC58G0F1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G1U3-1", "uniprot_id": [ { "id": "A0AC58G1U3_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G1U3", "type": "external" } ], "mass": 66699.0, "length": 602, "protein_name": "Rabphilin-3A", "gene_name": "rph3ab", "organism": "Zebrafish", "refseq_name": "rabphilin-3A isoform X1", "refseq_ac": [ { "id": "XP_073763702", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763702", "type": "external" } ], "gene_names_uniprotkb": "rph3ab", "gene_names_refseq": "rph3ab", "protein_names_uniprotkb": "Rabphilin-3A; Exophilin-1", "protein_names_refseq": "rabphilin-3A isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:563377)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays an essential role in docking and fusion steps of regulated exocytosis. At the presynaptic level, RPH3A is recruited by RAB3A to the synaptic vesicle membrane in a GTP-dependent manner where it modulates synaptic vesicle trafficking and calcium-triggered neurotransmitter release. In the post-synaptic compartment, forms a ternary complex with GRIN2A and DLG4 and regulates NMDA receptor stability. Also plays a role in the exocytosis of arginine vasopressin hormone., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008289 lipid binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0098850 extrinsic component of synaptic vesicle membrane;GO:0043197 dendritic spine;GO:0045202 synapse;GO:0045211 postsynaptic membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0045956 positive regulation of calcium ion-dependent exocytosis;GO:0099502 calcium-dependent activation of synaptic vesicle fusion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G1U3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G046-1", "uniprot_id": [ { "id": "A0AC58G046_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G046", "type": "external" } ], "mass": 117105.0, "length": 1048, "protein_name": "Solute carrier family 12 member 10, tandem duplicate 1 isoform X1", "gene_name": "slc12a10.1", "organism": "Zebrafish", "refseq_name": "solute carrier family 12 member 10, tandem duplicate 1 isoform X1", "refseq_ac": [ { "id": "XP_073763114", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763114", "type": "external" } ], "gene_names_uniprotkb": "slc12a10.1; si:dkey-114c3.1", "gene_names_refseq": "si:dkey-114c3.1; slc12a10.1", "protein_names_uniprotkb": "Solute carrier family 12 member 10, tandem duplicate 1 isoform X1", "protein_names_refseq": "solute carrier family 12 member 10, tandem duplicate 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:570849)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "19279294;24842048;26327813;38842519", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008511 sodium:potassium:chloride symporter activity", "go_cellular_component": "GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006884 cell volume homeostasis;GO:1902476 chloride transmembrane transport;GO:0035725 sodium ion transmembrane transport;GO:0055075 potassium ion homeostasis;GO:0055078 sodium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0AC58G046-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G011-1", "uniprot_id": [ { "id": "A0AC58G011_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G011", "type": "external" } ], "mass": 62856.0, "length": 569, "protein_name": "Serine/threonine-protein kinase 33", "gene_name": "stk33", "organism": "Zebrafish", "refseq_name": "serine/threonine-protein kinase 33 isoform X1", "refseq_ac": [ { "id": "XP_073762978", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073762978", "type": "external" } ], "gene_names_uniprotkb": "stk33; si:ch211-208c6.6; wu:fab03g11", "gene_names_refseq": "si:ch211-208c6.6; stk33; wu:fab03g11", "protein_names_uniprotkb": "Serine/threonine-protein kinase 33; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase 33 isoform X1", "tax_id": 7955, "disease": "spermatogenic failure 93 (Disease Ontology:DOID:0070592); depressive disorder (Disease Ontology:DOID:1596); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0016301 kinase activity", "go_cellular_component": "GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0007283 spermatogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G011-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G1J8-1", "uniprot_id": [ { "id": "A0AC58G1J8_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G1J8", "type": "external" } ], "mass": 199171.0, "length": 1791, "protein_name": "Inositol 1,4,5-triphosphate receptor associated 1 isoform X1", "gene_name": "mrvi1", "organism": "Zebrafish", "refseq_name": "inositol 1,4,5-triphosphate receptor associated 1 isoform X1", "refseq_ac": [ { "id": "XP_073763607", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763607", "type": "external" } ], "gene_names_uniprotkb": "mrvi1", "gene_names_refseq": "mrvi1", "protein_names_uniprotkb": "Inositol 1,4,5-triphosphate receptor associated 1 isoform X1", "protein_names_refseq": "inositol 1,4,5-triphosphate receptor associated 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100331961)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G1J8-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G1Z1-1", "uniprot_id": [ { "id": "A0AC58G1Z1_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G1Z1", "type": "external" } ], "mass": 44934.0, "length": 400, "protein_name": "B-cell receptor CD22", "gene_name": "zmp:0000000971", "organism": "Zebrafish", "refseq_name": "B-cell receptor CD22-like isoform X1", "refseq_ac": [ { "id": "XP_073763742", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763742", "type": "external" } ], "gene_names_uniprotkb": "zmp:0000000971", "gene_names_refseq": "zmp:0000000971", "protein_names_uniprotkb": "B-cell receptor CD22; Sialic acid-binding Ig-like lectin 2", "protein_names_refseq": "B-cell receptor CD22-like isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100332786)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Most highly expressed siglec (sialic acid-binding immunoglobulin-like lectin) on B-cells that plays a role in various aspects of B-cell biology including differentiation, antigen presentation, and trafficking to bone marrow. Binds to alpha 2,6-linked sialic acid residues of surface molecules such as CD22 itself, CD45 and IgM in a cis configuration. Can also bind to ligands on other cells as an adhesion molecule in a trans configuration. Acts as an inhibitory coreceptor on the surface of B-cells and inhibits B-cell receptor induced signaling, characterized by inhibition of the calcium mobilization and cellular activation. Mechanistically, the immunoreceptor tyrosine-based inhibitory motif domain is phosphorylated by the Src kinase LYN, which in turn leads to the recruitment of the protein tyrosine phosphatase 1/PTPN6, leading to the negative regulation of BCR signaling. If this negative signaling from is of sufficient strength, apoptosis of the B-cell can be induced., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G1Z1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2M1-1", "uniprot_id": [ { "id": "A0AC58G2M1_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2M1", "type": "external" } ], "mass": 41240.0, "length": 373, "protein_name": "Uncharacterized protein isoform X1", "gene_name": "LOC100334521", "organism": "Zebrafish", "refseq_name": "uncharacterized LOC100334521 precursor", "refseq_ac": [ { "id": "NP_001429909", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429909", "type": "external" } ], "gene_names_uniprotkb": "LOC100334521", "gene_names_refseq": "LOC100334521", "protein_names_uniprotkb": "Uncharacterized protein isoform X1", "protein_names_refseq": "uncharacterized LOC100334521 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100334521)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.11081671.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505373 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Sep 3, 2025 this sequence version replaced XP_073763989.1., [RefSeq]; Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58G2M2", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0042806 fucose binding", "go_cellular_component": "", "go_biological_process": "GO:0001868 regulation of complement activation, lectin pathway;GO:0010185 regulation of cellular defense response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2M1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G0I3-1", "uniprot_id": [ { "id": "A0AC58G0I3_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G0I3", "type": "external" } ], "mass": 36648.0, "length": 325, "protein_name": "Novel immune-type receptor 2a isoform X1", "gene_name": "nitr2a", "organism": "Zebrafish", "refseq_name": "novel immune-type receptor 2a isoform X1", "refseq_ac": [ { "id": "XP_073763269", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763269", "type": "external" } ], "gene_names_uniprotkb": "nitr2a; dZ169I8.1; nitr2.11; nitr2.18; nitr2.22; nitr2.6; nitr2.7; nitr2a_1-2; nitr2a_1; nitr2a_2; nitr2a_3; nitr2; si:busm1-186f8.2; si:dz186f8.2", "gene_names_refseq": "dZ169I8.1; nitr2.11; nitr2.18; nitr2.22; nitr2.6; nitr2.7; nitr2a_1-2; nitr2a_1; nitr2a_2; nitr2a_3; nitr2a; nitr2; si:busm1-186f8.2; si:dz186f8.2", "protein_names_uniprotkb": "Novel immune-type receptor 2a isoform X1", "protein_names_refseq": "novel immune-type receptor 2a isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G0I3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58FZZ8-1", "uniprot_id": [ { "id": "A0AC58FZZ8_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58FZZ8", "type": "external" } ], "mass": 70992.0, "length": 645, "protein_name": "B-cell receptor CD22-like", "gene_name": "LOC141375102", "organism": "Zebrafish", "refseq_name": "B-cell receptor CD22-like", "refseq_ac": [ { "id": "XP_073763094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763094", "type": "external" } ], "gene_names_uniprotkb": "LOC141375102", "gene_names_refseq": "LOC141375102", "protein_names_uniprotkb": "B-cell receptor CD22-like", "protein_names_refseq": "B-cell receptor CD22-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58FZZ8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G003-1", "uniprot_id": [ { "id": "A0AC58G003_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G003", "type": "external" } ], "mass": 78840.0, "length": 714, "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "shrprbck1r", "organism": "Zebrafish", "refseq_name": "ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X1", "refseq_ac": [ { "id": "XP_073763105", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763105", "type": "external" } ], "gene_names_uniprotkb": "shrprbck1r; HOIL-1; rbck1; zgc:175152", "gene_names_refseq": "HOIL-1; rbck1; shrprbck1r; zgc:175152", "protein_names_uniprotkb": "RanBP-type and C3HC4-type zinc finger-containing protein 1; 2.3.2.31; Heme-oxidized IRP2 ubiquitin ligase 1 homolog; Heme-oxidized IRP2 ubiquitin transferase 1 homolog", "protein_names_refseq": "ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58G021", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G003-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G002-1", "uniprot_id": [ { "id": "A0AC58G002_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G002", "type": "external" } ], "mass": 72752.0, "length": 650, "protein_name": "B-cell receptor CD22 isoform X1", "gene_name": "LOC101884507", "organism": "Zebrafish", "refseq_name": "B-cell receptor CD22 isoform X1", "refseq_ac": [ { "id": "XP_073763108", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763108", "type": "external" } ], "gene_names_uniprotkb": "LOC101884507", "gene_names_refseq": "LOC101884507", "protein_names_uniprotkb": "B-cell receptor CD22 isoform X1", "protein_names_refseq": "B-cell receptor CD22 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G002-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G0C2-1", "uniprot_id": [ { "id": "A0AC58G0C2_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G0C2", "type": "external" } ], "mass": 26085.0, "length": 230, "protein_name": "Novel immune-type receptor 3b isoform X1", "gene_name": "nitr3b", "organism": "Zebrafish", "refseq_name": "novel immune-type receptor 3b precursor", "refseq_ac": [ { "id": "NP_001007212", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007212", "type": "external" } ], "gene_names_uniprotkb": "nitr3b; nitr3b_2; nitr3d_7; nitr3r.1; nitr3r.3; nitr3r.9; nitr3; nitr; si:dz221h6.1", "gene_names_refseq": "nitr3b_2; nitr3b; nitr3d_7; nitr3r.1; nitr3r.3; nitr3r.9; nitr3; nitr; si:dz221h6.1", "protein_names_uniprotkb": "Novel immune-type receptor 3b isoform X1", "protein_names_refseq": "immune-type receptor; novel immune-type receptor 3, related 1; novel immune-type receptor 3, related 3; novel immune-type receptor 3b precursor", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588719.7622229.1, SRR32588725.3719857.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN18715719 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On or before Jun 24, 2025 this sequence version replaced XP_073763213.1, NP_001007212.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G0C2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G0C3-1", "uniprot_id": [ { "id": "A0AC58G0C3_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G0C3", "type": "external" } ], "mass": 43752.0, "length": 386, "protein_name": "Endophilin-A3a isoform X1", "gene_name": "sh3gl3a", "organism": "Zebrafish", "refseq_name": "endophilin-A3a isoform X1", "refseq_ac": [ { "id": "XP_073763117", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763117", "type": "external" } ], "gene_names_uniprotkb": "sh3gl3a; zgc:158742", "gene_names_refseq": "sh3gl3a; zgc:158742", "protein_names_uniprotkb": "Endophilin-A3a isoform X1", "protein_names_refseq": "endophilin-A3a isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G0C3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G0C5-1", "uniprot_id": [ { "id": "A0AC58G0C5_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G0C5", "type": "external" } ], "mass": 65616.0, "length": 601, "protein_name": "B-cell receptor CD22-like", "gene_name": "LOC103909373", "organism": "Zebrafish", "refseq_name": "B-cell receptor CD22-like", "refseq_ac": [ { "id": "XP_073763140", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763140", "type": "external" } ], "gene_names_uniprotkb": "LOC103909373", "gene_names_refseq": "LOC103909373", "protein_names_uniprotkb": "B-cell receptor CD22-like", "protein_names_refseq": "B-cell receptor CD22-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G0C5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G0E1-1", "uniprot_id": [ { "id": "A0AC58G0E1_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G0E1", "type": "external" } ], "mass": 58937.0, "length": 529, "protein_name": "Uncharacterized protein", "gene_name": "LOC141375103", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_073763143", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763143", "type": "external" } ], "gene_names_uniprotkb": "LOC141375103", "gene_names_refseq": "LOC141375103", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G0E1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G0F7-1", "uniprot_id": [ { "id": "A0AC58G0F7_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G0F7", "type": "external" } ], "mass": 58053.0, "length": 520, "protein_name": "B-cell receptor CD22", "gene_name": "si:ch211-1f22.3", "organism": "Zebrafish", "refseq_name": "B-cell receptor CD22-like", "refseq_ac": [ { "id": "XP_073763170", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763170", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-1f22.3", "gene_names_refseq": "si:ch211-1f22.3", "protein_names_uniprotkb": "B-cell receptor CD22; Sialic acid-binding Ig-like lectin 2", "protein_names_refseq": "B-cell receptor CD22-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Most highly expressed siglec (sialic acid-binding immunoglobulin-like lectin) on B-cells that plays a role in various aspects of B-cell biology including differentiation, antigen presentation, and trafficking to bone marrow. Binds to alpha 2,6-linked sialic acid residues of surface molecules such as CD22 itself, CD45 and IgM in a cis configuration. Can also bind to ligands on other cells as an adhesion molecule in a trans configuration. Acts as an inhibitory coreceptor on the surface of B-cells and inhibits B-cell receptor induced signaling, characterized by inhibition of the calcium mobilization and cellular activation. Mechanistically, the immunoreceptor tyrosine-based inhibitory motif domain is phosphorylated by the Src kinase LYN, which in turn leads to the recruitment of the protein tyrosine phosphatase 1/PTPN6, leading to the negative regulation of BCR signaling. If this negative signaling from is of sufficient strength, apoptosis of the B-cell can be induced., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G0F7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G0K2-1", "uniprot_id": [ { "id": "A0AC58G0K2_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G0K2", "type": "external" } ], "mass": 60041.0, "length": 528, "protein_name": "Beta,beta-carotene 15,15'-dioxygenase isoform X1", "gene_name": "bco1", "organism": "Zebrafish", "refseq_name": "beta,beta-carotene 15,15'-dioxygenase isoform X1", "refseq_ac": [ { "id": "XP_073763284", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763284", "type": "external" } ], "gene_names_uniprotkb": "bco1; b-diox; bcdo1; bcdo; bcmo1a; bcmo1; bcox", "gene_names_refseq": "b-diox; bcdo1; bcdo; bcmo1a; bcmo1; bco1; bcox", "protein_names_uniprotkb": "Beta,beta-carotene 15,15'-dioxygenase isoform X1", "protein_names_refseq": "beta,beta-carotene 15,15'-dioxygenase isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G0K2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G0N0-1", "uniprot_id": [ { "id": "A0AC58G0N0_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G0N0", "type": "external" } ], "mass": 135632.0, "length": 1194, "protein_name": "Uncharacterized protein", "gene_name": "LOC141375109", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_073763311", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763311", "type": "external" } ], "gene_names_uniprotkb": "LOC141375109", "gene_names_refseq": "LOC141375109", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G0N0-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G0N2-1", "uniprot_id": [ { "id": "A0AC58G0N2_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G0N2", "type": "external" } ], "mass": 57335.0, "length": 496, "protein_name": "GTPase IMAP family member 8", "gene_name": "LOC100334305", "organism": "Zebrafish", "refseq_name": "GTPase IMAP family member 8", "refseq_ac": [ { "id": "XP_073763252", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763252", "type": "external" } ], "gene_names_uniprotkb": "LOC100334305", "gene_names_refseq": "LOC100334305", "protein_names_uniprotkb": "GTPase IMAP family member 8", "protein_names_refseq": "GTPase IMAP family member 8", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G0N2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G0N3-1", "uniprot_id": [ { "id": "A0AC58G0N3_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G0N3", "type": "external" } ], "mass": 91001.0, "length": 819, "protein_name": "Cadherin-16", "gene_name": "cdh16", "organism": "Zebrafish", "refseq_name": "cadherin-16", "refseq_ac": [ { "id": "XP_073763310", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763310", "type": "external" } ], "gene_names_uniprotkb": "cdh16", "gene_names_refseq": "cdh16", "protein_names_uniprotkb": "Cadherin-16", "protein_names_refseq": "cadherin-16", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G0N3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G0N6-1", "uniprot_id": [ { "id": "A0AC58G0N6_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G0N6", "type": "external" } ], "mass": 53968.0, "length": 486, "protein_name": "Adhesion G protein-coupled receptor E3-like", "gene_name": "LOC103909390", "organism": "Zebrafish", "refseq_name": "adhesion G protein-coupled receptor E3-like", "refseq_ac": [ { "id": "XP_073763277", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763277", "type": "external" } ], "gene_names_uniprotkb": "LOC103909390", "gene_names_refseq": "LOC103909390", "protein_names_uniprotkb": "Adhesion G protein-coupled receptor E3-like", "protein_names_refseq": "adhesion G protein-coupled receptor E3-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G0N6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G0R9-1", "uniprot_id": [ { "id": "A0AC58G0R9_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G0R9", "type": "external" } ], "mass": 47156.0, "length": 427, "protein_name": "Uncharacterized protein isoform X1", "gene_name": "LOC141375121", "organism": "Zebrafish", "refseq_name": "uncharacterized protein isoform X1", "refseq_ac": [ { "id": "XP_073763339", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763339", "type": "external" } ], "gene_names_uniprotkb": "LOC141375121", "gene_names_refseq": "LOC141375121", "protein_names_uniprotkb": "Uncharacterized protein isoform X1", "protein_names_refseq": "uncharacterized protein isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G145-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G153-1", "uniprot_id": [ { "id": "A0AC58G153_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G153", "type": "external" } ], "mass": 35622.0, "length": 307, "protein_name": "C-type lectin domain-containing protein", "gene_name": "LOC141375137", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_073763440", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763440", "type": "external" } ], "gene_names_uniprotkb": "LOC141375137", "gene_names_refseq": "LOC141375137", "protein_names_uniprotkb": "C-type lectin domain-containing protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G170-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G175-1", "uniprot_id": [ { "id": "A0AC58G175_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G175", "type": "external" } ], "mass": 28922.0, "length": 252, "protein_name": "P-selectin-like", "gene_name": "LOC141375154", "organism": "Zebrafish", "refseq_name": "P-selectin-like", "refseq_ac": [ { "id": "XP_073763491", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763491", "type": "external" } ], "gene_names_uniprotkb": "LOC141375154", "gene_names_refseq": "LOC141375154", "protein_names_uniprotkb": "P-selectin-like", "protein_names_refseq": "P-selectin-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G175-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G187-1", "uniprot_id": [ { "id": "A0AC58G187_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G187", "type": "external" } ], "mass": 22512.0, "length": 229, "protein_name": "Uncharacterized protein", "gene_name": "LOC141375156", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_073763492", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763492", "type": "external" } ], "gene_names_uniprotkb": "LOC141375156", "gene_names_refseq": "LOC141375156", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G187-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G194-1", "uniprot_id": [ { "id": "A0AC58G194_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G194", "type": "external" } ], "mass": 28595.0, "length": 250, "protein_name": "GTPase IMAP family member 4-like", "gene_name": "LOC137495296", "organism": "Zebrafish", "refseq_name": "GTPase IMAP family member 4-like", "refseq_ac": [ { "id": "XP_073763493", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763493", "type": "external" } ], "gene_names_uniprotkb": "LOC137495296", "gene_names_refseq": "LOC137495296", "protein_names_uniprotkb": "GTPase IMAP family member 4-like", "protein_names_refseq": "GTPase IMAP family member 4-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G194-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G196-1", "uniprot_id": [ { "id": "A0AC58G196_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G196", "type": "external" } ], "mass": 30104.0, "length": 270, "protein_name": "Immunoglobulin V-set domain-containing protein", "gene_name": "LOC137495978", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_073763485", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763485", "type": "external" } ], "gene_names_uniprotkb": "LOC137495978", "gene_names_refseq": "LOC137495978", "protein_names_uniprotkb": "Immunoglobulin V-set domain-containing protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G196-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G1A8-1", "uniprot_id": [ { "id": "A0AC58G1A8_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G1A8", "type": "external" } ], "mass": 55192.0, "length": 488, "protein_name": "Uncharacterized protein", "gene_name": "LOC141375147", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_073763488", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763488", "type": "external" } ], "gene_names_uniprotkb": "LOC141375147", "gene_names_refseq": "LOC141375147", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays a role in immunological synaptic F-actin density and architecture organization. Regulates actin reorganization in lymphocytes, possibly through the modulation of Rac1 activity. Required for the formation of membrane ruffles during macropinocytosis. Plays a role in cell migration and is required for the formation of cup-like structures during trans-endothelial migration of leukocytes. Binds phospholipids in an activation-dependent manner; thereby acting as an anchor for other proteins to the plasma membrane (PM). Plays a role in exocytosis of cytotoxic granules (CG) by lymphocytes/Component of the exocytosis machinery in natural killer (NK) and CD8+ T cells. Promotes the docking of cytotoxic granules (CG) to the plasma membrane through the interaction with UNC13D. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G1P4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G1P3-1", "uniprot_id": [ { "id": "A0AC58G1P3_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G1P3", "type": "external" } ], "mass": 155191.0, "length": 1422, "protein_name": "PH domain leucine-rich repeat-containing protein phosphatase 2", "gene_name": "phlpp2", "organism": "Zebrafish", "refseq_name": "PH domain leucine-rich repeat-containing protein phosphatase 2", "refseq_ac": [ { "id": "XP_073763654", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763654", "type": "external" } ], "gene_names_uniprotkb": "phlpp2", "gene_names_refseq": "phlpp2", "protein_names_uniprotkb": "PH domain leucine-rich repeat-containing protein phosphatase 2; 3.1.3.16; PH domain leucine-rich repeat-containing protein phosphatase-like", "protein_names_refseq": "PH domain leucine-rich repeat-containing protein phosphatase 2", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Protein phosphatase involved in regulation of Akt and PKC signaling. Mediates dephosphorylation in the C-terminal domain hydrophobic motif of members of the AGC Ser/Thr protein kinase family; specifically acts on 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser-657' of PRKCA. Akt regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of Akt triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylates STK4 on 'Thr-387' leading to STK4 activation and apoptosis. Dephosphorylates RPS6KB1 and is involved in regulation of cap-dependent translation. Inhibits cancer cell proliferation and may act as a tumor suppressor. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation. Dephosphorylates RAF1 inhibiting its kinase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G1P3-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G1Q3-1", "uniprot_id": [ { "id": "A0AC58G1Q3_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G1Q3", "type": "external" } ], "mass": 103726.0, "length": 898, "protein_name": "Uncharacterized protein isoform X1", "gene_name": "LOC101886687", "organism": "Zebrafish", "refseq_name": "uncharacterized protein isoform X1", "refseq_ac": [ { "id": "XP_073763671", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763671", "type": "external" } ], "gene_names_uniprotkb": "LOC101886687", "gene_names_refseq": "LOC101886687", "protein_names_uniprotkb": "Uncharacterized protein isoform X1", "protein_names_refseq": "uncharacterized protein isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G1Q3-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G1R5-1", "uniprot_id": [ { "id": "A0AC58G1R5_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G1R5", "type": "external" } ], "mass": 58475.0, "length": 524, "protein_name": "B-cell receptor CD22", "gene_name": "LOC100006649", "organism": "Zebrafish", "refseq_name": "B-cell receptor CD22", "refseq_ac": [ { "id": "XP_073763684", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763684", "type": "external" } ], "gene_names_uniprotkb": "LOC100006649", "gene_names_refseq": "LOC100006649", "protein_names_uniprotkb": "B-cell receptor CD22; Sialic acid-binding Ig-like lectin 2", "protein_names_refseq": "B-cell receptor CD22", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Most highly expressed siglec (sialic acid-binding immunoglobulin-like lectin) on B-cells that plays a role in various aspects of B-cell biology including differentiation, antigen presentation, and trafficking to bone marrow. Binds to alpha 2,6-linked sialic acid residues of surface molecules such as CD22 itself, CD45 and IgM in a cis configuration. Can also bind to ligands on other cells as an adhesion molecule in a trans configuration. Acts as an inhibitory coreceptor on the surface of B-cells and inhibits B-cell receptor induced signaling, characterized by inhibition of the calcium mobilization and cellular activation. Mechanistically, the immunoreceptor tyrosine-based inhibitory motif domain is phosphorylated by the Src kinase LYN, which in turn leads to the recruitment of the protein tyrosine phosphatase 1/PTPN6, leading to the negative regulation of BCR signaling. If this negative signaling from is of sufficient strength, apoptosis of the B-cell can be induced., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58G1R8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G1R5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G1S2-1", "uniprot_id": [ { "id": "A0AC58G1S2_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G1S2", "type": "external" } ], "mass": 213717.0, "length": 1913, "protein_name": "Low-density lipoprotein receptor-related protein 4 isoform X1", "gene_name": "lrp4", "organism": "Zebrafish", "refseq_name": "low-density lipoprotein receptor-related protein 4 isoform X1", "refseq_ac": [ { "id": "XP_073763685", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763685", "type": "external" } ], "gene_names_uniprotkb": "lrp4", "gene_names_refseq": "lrp4", "protein_names_uniprotkb": "Low-density lipoprotein receptor-related protein 4 isoform X1", "protein_names_refseq": "low-density lipoprotein receptor-related protein 4 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G1S2-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G1V3-1", "uniprot_id": [ { "id": "A0AC58G1V3_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G1V3", "type": "external" } ], "mass": 14467.0, "length": 131, "protein_name": "Mucin-6-like", "gene_name": "LOC141375212", "organism": "Zebrafish", "refseq_name": "mucin-6-like", "refseq_ac": [ { "id": "XP_073763723", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763723", "type": "external" } ], "gene_names_uniprotkb": "LOC141375212", "gene_names_refseq": "LOC141375212", "protein_names_uniprotkb": "Mucin-6-like", "protein_names_refseq": "mucin-6-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Orphan adhesion G-protein coupled receptor (aGPCR), which mediates synapse specificity. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. Isoform 1 is specifically coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G1Y3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G1Z8-1", "uniprot_id": [ { "id": "A0AC58G1Z8_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G1Z8", "type": "external" } ], "mass": 33542.0, "length": 295, "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC141375214", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_073763766", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763766", "type": "external" } ], "gene_names_uniprotkb": "LOC141375214", "gene_names_refseq": "LOC141375214", "protein_names_uniprotkb": "Ig-like domain-containing protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2I0-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2I1-1", "uniprot_id": [ { "id": "A0AC58G2I1_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2I1", "type": "external" } ], "mass": 138098.0, "length": 1239, "protein_name": "Uncharacterized protein si:cabz01007807.1", "gene_name": "si:cabz01007807.1", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:cabz01007807.1", "refseq_ac": [ { "id": "XP_073763938", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763938", "type": "external" } ], "gene_names_uniprotkb": "si:cabz01007807.1", "gene_names_refseq": "si:cabz01007807.1", "protein_names_uniprotkb": "Uncharacterized protein si:cabz01007807.1", "protein_names_refseq": "uncharacterized protein si:cabz01007807.1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2I1-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2I4-1", "uniprot_id": [ { "id": "A0AC58G2I4_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2I4", "type": "external" } ], "mass": 53517.0, "length": 480, "protein_name": "B-cell receptor CD22-like isoform X1", "gene_name": "LOC141375242", "organism": "Zebrafish", "refseq_name": "B-cell receptor CD22-like isoform X1", "refseq_ac": [ { "id": "XP_073763946", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763946", "type": "external" } ], "gene_names_uniprotkb": "LOC141375242", "gene_names_refseq": "LOC141375242", "protein_names_uniprotkb": "B-cell receptor CD22-like isoform X1", "protein_names_refseq": "B-cell receptor CD22-like isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58G2K3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2I4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2I7-1", "uniprot_id": [ { "id": "A0AC58G2I7_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2I7", "type": "external" } ], "mass": 37303.0, "length": 325, "protein_name": "Macrophage mannose receptor 1-like", "gene_name": "LOC141375233", "organism": "Zebrafish", "refseq_name": "macrophage mannose receptor 1-like", "refseq_ac": [ { "id": "XP_073763928", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763928", "type": "external" } ], "gene_names_uniprotkb": "LOC141375233", "gene_names_refseq": "LOC141375233", "protein_names_uniprotkb": "Macrophage mannose receptor 1-like", "protein_names_refseq": "macrophage mannose receptor 1-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2I7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2J0-1", "uniprot_id": [ { "id": "A0AC58G2J0_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2J0", "type": "external" } ], "mass": 24569.0, "length": 218, "protein_name": "Calcium-binding protein 2", "gene_name": "si:cabz01076231.1", "organism": "Zebrafish", "refseq_name": "si:cabz01076231.1", "refseq_ac": [ { "id": "NP_001427723", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001427723", "type": "external" } ], "gene_names_uniprotkb": "si:cabz01076231.1", "gene_names_refseq": "si:cabz01076231.1", "protein_names_uniprotkb": "Calcium-binding protein 2", "protein_names_refseq": "si:cabz01076231.1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588719.14923223.1, SRR32588729.28519041.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505376 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2J0-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2J7-1", "uniprot_id": [ { "id": "A0AC58G2J7_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2J7", "type": "external" } ], "mass": 126088.0, "length": 1114, "protein_name": "Protein translocase subunit SecA-like", "gene_name": "LOC141375240", "organism": "Zebrafish", "refseq_name": "protein translocase subunit SecA-like", "refseq_ac": [ { "id": "XP_073763943", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763943", "type": "external" } ], "gene_names_uniprotkb": "LOC141375240", "gene_names_refseq": "LOC141375240", "protein_names_uniprotkb": "Protein translocase subunit SecA-like", "protein_names_refseq": "protein translocase subunit SecA-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2J7-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2K7-1", "uniprot_id": [ { "id": "A0AC58G2K7_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2K7", "type": "external" } ], "mass": 62198.0, "length": 553, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC141375244", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC141375244", "refseq_ac": [ { "id": "NP_001314756", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314756", "type": "external" } ], "gene_names_uniprotkb": "LOC141375244", "gene_names_refseq": "si:dkey-192d15.1; si:dkey-192d15.2", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase Nek4-like; uncharacterized protein LOC141375244", "tax_id": 7955, "disease": "", "pathway": " (dre:141375244)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.42017239.1, SRR32588719.14973693.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On or before Dec 5, 2025 this sequence version replaced XP_068078606.1, XP_009301118.1. Sequence Note:., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0R4IF32;A0A8M1P8C4", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006869 lipid transport;GO:0042157 lipoprotein metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2K7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2K8-1", "uniprot_id": [ { "id": "A0AC58G2K8_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2K8", "type": "external" } ], "mass": 61553.0, "length": 533, "protein_name": "AIG1-type G domain-containing protein", "gene_name": "LOC141375247", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_073763985", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763985", "type": "external" } ], "gene_names_uniprotkb": "LOC141375247", "gene_names_refseq": "LOC141375247", "protein_names_uniprotkb": "AIG1-type G domain-containing protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2K8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2K9-1", "uniprot_id": [ { "id": "A0AC58G2K9_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2K9", "type": "external" } ], "mass": 58362.0, "length": 534, "protein_name": "Fucolectin tachylectin-4 pentraxin-1 domain-containing protein", "gene_name": "LOC137490250", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_073763984", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763984", "type": "external" } ], "gene_names_uniprotkb": "LOC137490250", "gene_names_refseq": "LOC137490250", "protein_names_uniprotkb": "Fucolectin tachylectin-4 pentraxin-1 domain-containing protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2K9-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2L3-1", "uniprot_id": [ { "id": "A0AC58G2L3_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2L3", "type": "external" } ], "mass": 60698.0, "length": 544, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "si:ch211-217i17.1", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch211-217i17.1", "refseq_ac": [ { "id": "XP_073763977", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073763977", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-217i17.1", "gene_names_refseq": "si:ch211-217i17.1", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "uncharacterized protein si:ch211-217i17.1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", 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"https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2L3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2L8-1", "uniprot_id": [ { "id": "A0AC58G2L8_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2L8", "type": "external" } ], "mass": 62028.0, "length": 533, "protein_name": "AIG1-type G domain-containing protein", "gene_name": "si:dkey-187j14.1", "organism": "Zebrafish", 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58G2R4;A0AC58G2R5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2Q9-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2S1-1", "uniprot_id": [ { "id": "A0AC58G2S1_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2S1", "type": "external" } ], "mass": 42523.0, "length": 367, "protein_name": "C-type mannose receptor 2-like isoform X1", "gene_name": "si:ch211-63p21.4", "organism": "Zebrafish", "refseq_name": "C-type mannose receptor 2-like isoform X1", "refseq_ac": [ { "id": "XP_073764017", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764017", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-63p21.4", "gene_names_refseq": "si:ch211-63p21.4", "protein_names_uniprotkb": "C-type mannose receptor 2-like isoform X1", "protein_names_refseq": "C-type mannose receptor 2-like isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0043325 phosphatidylinositol-3,4-bisphosphate binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0AC58G5P4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2X5-1", "uniprot_id": [ { "id": "A0AC58G2X5_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2X5", "type": "external" } ], "mass": 36241.0, "length": 322, "protein_name": "Uncharacterized protein si:cabz01074944.1 isoform X1", "gene_name": "si:cabz01074944.1", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:cabz01074944.1 isoform X1", "refseq_ac": [ { "id": "XP_073764091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764091", "type": "external" } ], "gene_names_uniprotkb": "si:cabz01074944.1", "gene_names_refseq": "si:cabz01074944.1", "protein_names_uniprotkb": "Uncharacterized protein si:cabz01074944.1 isoform X1", "protein_names_refseq": "uncharacterized protein si:cabz01074944.1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:101882779)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005911 cell-cell junction;GO:0016020 membrane", "go_biological_process": "GO:0006955 immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2X5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G472-1", "uniprot_id": [ { "id": "A0AC58G472_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G472", "type": "external" } ], "mass": 101805.0, "length": 972, "protein_name": "Uncharacterized protein si:ch73-211e3.1 isoform X1", "gene_name": "si:ch73-211e3.1", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch73-211e3.1 isoform X1", "refseq_ac": [ { "id": "XP_073764532", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764532", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-211e3.1", "gene_names_refseq": "si:ch73-211e3.1", "protein_names_uniprotkb": "Uncharacterized protein si:ch73-211e3.1 isoform X1", "protein_names_refseq": "uncharacterized protein si:ch73-211e3.1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:103911379)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G472-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G5D7-1", "uniprot_id": [ { "id": "A0AC58G5D7_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G5D7", "type": "external" } ], "mass": 132614.0, "length": 1181, "protein_name": "VPS10 domain-containing receptor SorCS2", "gene_name": "sorcs2", "organism": "Zebrafish", "refseq_name": "VPS10 domain-containing receptor SorCS2 isoform X1", "refseq_ac": [ { "id": "XP_073764938", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764938", "type": "external" } ], "gene_names_uniprotkb": "sorcs2", "gene_names_refseq": "sorcs2", "protein_names_uniprotkb": "VPS10 domain-containing receptor SorCS2", "protein_names_refseq": "VPS10 domain-containing receptor SorCS2 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0043197 dendritic spine;GO:0043204 perikaryon;GO:0031901 early endosome membrane;GO:0055038 recycling endosome membrane;GO:0098839 postsynaptic density membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G5D7-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G3R0-1", "uniprot_id": [ { "id": "A0AC58G3R0_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G3R0", "type": "external" } ], "mass": 27617.0, "length": 249, "protein_name": "Uncharacterized protein si:ch211-212k18.9 isoform X1", "gene_name": "si:ch211-212k18.9", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch211-212k18.9 isoform X1", "refseq_ac": [ { "id": "XP_073764374", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764374", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-212k18.9", "gene_names_refseq": "si:ch211-212k18.9", "protein_names_uniprotkb": "Uncharacterized protein si:ch211-212k18.9 isoform X1", "protein_names_refseq": "uncharacterized protein si:ch211-212k18.9 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100334500)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G3R0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G352-1", "uniprot_id": [ { "id": "A0AC58G352_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G352", "type": "external" } ], "mass": 68959.0, "length": 626, "protein_name": "Protein Lines homolog 1 isoform X1", "gene_name": "lins1", "organism": "Zebrafish", "refseq_name": "protein Lines homolog 1 isoform X1", "refseq_ac": [ { "id": "XP_073764161", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764161", "type": "external" } ], "gene_names_uniprotkb": "lins1", "gene_names_refseq": "lins1", "protein_names_uniprotkb": "Protein Lines homolog 1 isoform X1", "protein_names_refseq": "protein Lines homolog 1 isoform X1", "tax_id": 7955, "disease": "autosomal recessive intellectual developmental disorder 27 (Disease Ontology:DOID:0081193)", "pathway": " (dre:798262)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Guanyl-nucleotide exchange factor that regulates small GTPases of the Rab family. Converts GDP-bound inactive form of RAB27A and RAB27B to the GTP-bound active forms. Converts GDP-bound inactive form of RAB3A, RAB3C and RAB3D to the GTP-bound active forms, GTPases involved in synaptic vesicle exocytosis and vesicle secretion. Plays a role in synaptic vesicle formation and in vesicle trafficking at the neuromuscular junction. Involved in up-regulating a post-docking step of synaptic exocytosis in central synapses. Probably by binding to the motor proteins KIF1B and KIF1A, mediates motor-dependent transport of GTP-RAB3A-positive vesicles to the presynaptic nerve terminals. Plays a role in TNFA-mediated activation of the MAPK pathway, including ERK1/2. May link TNFRSF1A with MAP kinase activation. May be involved in the regulation of TNFA-induced apoptosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:0016301 kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G4V6-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G3K4-1", "uniprot_id": [ { "id": "A0AC58G3K4_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G3K4", "type": "external" } ], "mass": 37128.0, "length": 327, "protein_name": "Novel immune-type receptor 2b isoform X1", "gene_name": "nitr2b", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "nitr2b", "gene_names_refseq": "", "protein_names_uniprotkb": "Novel immune-type receptor 2b isoform X1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:60647)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0002376 immune system process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G3K4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G442-1", "uniprot_id": [ { "id": "A0AC58G442_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G442", "type": "external" } ], "mass": 39873.0, "length": 362, "protein_name": "Prostaglandin reductase 1", "gene_name": "ptgr1.2", "organism": "Zebrafish", "refseq_name": "prostaglandin reductase 1 isoform X1", "refseq_ac": [ { "id": "XP_073764509", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764509", "type": "external" } ], "gene_names_uniprotkb": "ptgr1.2", "gene_names_refseq": "ptgr1.2", "protein_names_uniprotkb": "Prostaglandin reductase 1; 1.3.1.48; 1.3.1.74; 15-oxoprostaglandin 13-reductase; Dithiolethione-inducible gene 1 protein; Leukotriene B4 12-hydroxydehydrogenase; NAD(P)H-dependent alkenal/one oxidoreductase", "protein_names_refseq": "prostaglandin reductase 1 isoform X1", "tax_id": 7955, "disease": "hypertension (Disease Ontology:DOID:10763)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.48", "type": "external" }, { "id": "1.3.1.74", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.74", "type": "external" } ], "go_molecular_function": "GO:0032440 2-alkenal reductase [NAD(P)H] activity;GO:0047522 15-oxoprostaglandin 13-reductase [NAD(P)+] activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006693 prostaglandin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G442-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G545-1", "uniprot_id": [ { "id": "A0AC58G545_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G545", "type": "external" } ], "mass": 67696.0, "length": 593, "protein_name": "Alpha-ketoglutarate-dependent dioxygenase FTO", "gene_name": "fto", "organism": "Zebrafish", "refseq_name": "alpha-ketoglutarate-dependent dioxygenase FTO isoform X1", "refseq_ac": [ { "id": "XP_073764853", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764853", "type": "external" } ], "gene_names_uniprotkb": "fto", "gene_names_refseq": "fto", "protein_names_uniprotkb": "Alpha-ketoglutarate-dependent dioxygenase FTO; 1.14.11.53; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; tRNA N1-methyl adenine demethylase FTO", "protein_names_refseq": "alpha-ketoglutarate-dependent dioxygenase FTO isoform X1", "tax_id": 7955, "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); aortic valve disease 2 (Disease Ontology:DOID:0080334); traumatic brain injury (Disease Ontology:DOID:0081292); hypertension (Disease Ontology:DOID:10763); essential hypertension (Disease Ontology:DOID:10825); sciatic neuropathy (Disease Ontology:DOID:11446); cardiovascular system disease (Disease Ontology:DOID:1287); nuclear senile cataract (Disease Ontology:DOID:13963); transient cerebral ischemia (Disease Ontology:DOID:224); coronary artery disease (Disease Ontology:DOID:3393); renal cell carcinoma (Disease Ontology:DOID:4450); clear cell renal cell carcinoma (Disease Ontology:DOID:4467); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); abdominal aortic aneurysm (Disease Ontology:DOID:7693); type 2 diabetes mellitus (Disease Ontology:DOID:9352); pulmonary embolism (Disease Ontology:DOID:9477); multiple myeloma (Disease Ontology:DOID:9538); diabetic neuropathy (Disease Ontology:DOID:9743); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:553363)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 20, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.53", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.53", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:1990931 mRNA N6-methyladenosine dioxygenase activity;GO:0035516 broad specificity oxidative DNA demethylase activity;GO:0051213 dioxygenase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016607 nuclear speck", "go_biological_process": "GO:0060972 left/right pattern formation;GO:0040014 regulation of multicellular organism growth;GO:0006307 DNA alkylation repair;GO:0060271 cilium assembly;GO:0090263 positive regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G545-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G5N0-1", "uniprot_id": [ { "id": "A0AC58G5N0_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G5N0", "type": "external" } ], "mass": 56154.0, "length": 500, "protein_name": "Double C2-like domains, gamma isoform X1", "gene_name": "doc2g", "organism": "Zebrafish", "refseq_name": "double C2-like domains, gamma isoform X1", "refseq_ac": [ { "id": "XP_073765043", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765043", "type": "external" } ], "gene_names_uniprotkb": "doc2g; doc2d; si:dkeyp-110g5.1", "gene_names_refseq": "doc2d; doc2g; si:dkeyp-110g5.1", "protein_names_uniprotkb": "Double C2-like domains, gamma isoform X1", "protein_names_refseq": "double C2-like domains, gamma isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100002795)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "20078875;24878530;26469318;27189481;28252024;31415728", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0016020 membrane;GO:0045202 synapse;GO:0098793 presynapse", "go_biological_process": "GO:0045956 positive regulation of calcium ion-dependent exocytosis;GO:0099502 calcium-dependent activation of synaptic vesicle fusion", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0AC58G5N0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G627-1", "uniprot_id": [ { "id": "A0AC58G627_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G627", "type": "external" } ], "mass": 47390.0, "length": 428, "protein_name": "Leucine-rich repeat and transmembrane domain-containing protein 1 isoform X1", "gene_name": "lrtm1", "organism": "Zebrafish", "refseq_name": "leucine-rich repeat and transmembrane domain-containing protein 1 isoform X1", "refseq_ac": [ { "id": "XP_073765184", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765184", "type": "external" } ], "gene_names_uniprotkb": "lrtm1", "gene_names_refseq": "lrtm1", "protein_names_uniprotkb": "Leucine-rich repeat and transmembrane domain-containing protein 1 isoform X1", "protein_names_refseq": "leucine-rich repeat and transmembrane domain-containing protein 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:101883439)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "21873635", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0071805 potassium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0AC58G627-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G5Z4-1", "uniprot_id": [ { "id": "A0AC58G5Z4_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G5Z4", "type": "external" } ], "mass": 11923.0, "length": 109, "protein_name": "Ragulator complex protein LAMTOR5", "gene_name": "lamtor5", "organism": "Zebrafish", "refseq_name": "ragulator complex protein LAMTOR5 isoform X1", "refseq_ac": [ { "id": "XP_073765147", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765147", "type": "external" } ], "gene_names_uniprotkb": "lamtor5; si:dkey-176g4.2", "gene_names_refseq": "lamtor5; si:dkey-176g4.2", "protein_names_uniprotkb": "Ragulator complex protein LAMTOR5; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5", "protein_names_refseq": "ragulator complex protein LAMTOR5 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100333504); (R-DRE-1632852); (R-DRE-165159); (R-DRE-166208); (R-DRE-380972); (R-DRE-5628897); (R-DRE-8943724); (R-DRE-9639288)", "pathway_count": 8, "publication_count": 4, "publication_id_list": "24307675;28252024;31562209;34988408", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2Y5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G603-1", "uniprot_id": [ { "id": "A0AC58G603_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G603", "type": "external" } ], "mass": 68790.0, "length": 613, "protein_name": "AT-rich interactive domain-containing protein 5A isoform X1", "gene_name": "arid5a", "organism": "Zebrafish", "refseq_name": "AT-rich interactive domain-containing protein 5A isoform X1", "refseq_ac": [ { "id": "XP_073765165", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765165", "type": "external" } ], "gene_names_uniprotkb": "arid5a", "gene_names_refseq": "arid5a", "protein_names_uniprotkb": "AT-rich interactive domain-containing protein 5A isoform X1", "protein_names_refseq": "AT-rich interactive domain-containing protein 5A isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100462698)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "24240475;26469318;27189481", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. 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The reference sequence was derived from JBMGRA010000008.1. On or before Aug 26, 2025 this sequence version replaced XP_073765080.1, NP_001035472.2., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58G5S7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0AC58G5S6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G3I5-1", "uniprot_id": [ { "id": "A0AC58G3I5_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G3I5", "type": "external" } ], "mass": 40655.0, "length": 360, "protein_name": "Novel immune-type receptor 3a isoform X1", "gene_name": "nitr3a; nitr3b", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "nitr3a; nitr3b; nitr3a; nitr3b_2; nitr3d_7; nitr3r.1; nitr3r.3; nitr3r.9; nitr3; nitr; si:dz221h6.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Novel immune-type receptor 3a isoform X1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:60659)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "18248169;18565225;20012603", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0002376 immune system process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0AC58G3I5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G5E2-1", "uniprot_id": [ { "id": "A0AC58G5E2_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G5E2", "type": "external" } ], "mass": 57278.0, "length": 503, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "si:dkey-58i8.5", "organism": "Zebrafish", "refseq_name": "si:dkey-58i8.5", "refseq_ac": [ { "id": "NP_001429493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429493", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-58i8.5", "gene_names_refseq": "si:dkey-58i8.5", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "si:dkey-58i8.5", "tax_id": 7955, "disease": "", "pathway": " (dre:100329858)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588728.35844157.1, SRR32588722.11206088.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02418766, SAMN02418767 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Aug 13, 2025 this sequence version replaced XP_073764960.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G5E2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G368-1", "uniprot_id": [ { "id": "A0AC58G368_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G368", "type": "external" } ], "mass": 47831.0, "length": 403, "protein_name": "Ceramide synthase 3 isoform X1", "gene_name": "cers3a", "organism": "Zebrafish", "refseq_name": "ceramide synthase 3 isoform X1", "refseq_ac": [ { "id": "XP_073764169", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764169", "type": "external" } ], "gene_names_uniprotkb": "cers3a", "gene_names_refseq": "cers3a", "protein_names_uniprotkb": "Ceramide synthase 3 isoform X1", "protein_names_refseq": "ceramide synthase 3 isoform X1", "tax_id": 7955, "disease": "autosomal recessive congenital ichthyosis 9 (Disease Ontology:DOID:0060718)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G368-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G4M4-1", "uniprot_id": [ { "id": "A0AC58G4M4_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G4M4", "type": "external" } ], "mass": 95660.0, "length": 861, "protein_name": "Semaphorin-4B isoform X1", "gene_name": "sema4bb", "organism": "Zebrafish", "refseq_name": "semaphorin-4B isoform X1", "refseq_ac": [ { "id": "XP_073764684", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764684", "type": "external" } ], "gene_names_uniprotkb": "sema4bb", "gene_names_refseq": "sema4bb", "protein_names_uniprotkb": "Semaphorin-4B isoform X1", "protein_names_refseq": "semaphorin-4B isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G4M4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G311-1", "uniprot_id": [ { "id": "A0AC58G311_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G311", "type": "external" } ], "mass": 47088.0, "length": 426, "protein_name": "Uncharacterized protein isoform X1", "gene_name": "LOC108179133", "organism": "Zebrafish", "refseq_name": "uncharacterized protein isoform X1", "refseq_ac": [ { "id": "XP_073764105", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764105", "type": "external" } ], "gene_names_uniprotkb": "LOC108179133", "gene_names_refseq": "LOC108179133", "protein_names_uniprotkb": "Uncharacterized protein isoform X1", "protein_names_refseq": "uncharacterized protein isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G311-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2V6-1", "uniprot_id": [ { "id": "A0AC58G2V6_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2V6", "type": "external" } ], "mass": 67008.0, "length": 595, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 46 isoform X1", "gene_name": "LOC100535728", "organism": "Zebrafish", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 46 isoform X1", "refseq_ac": [ { "id": "XP_073764074", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764074", "type": "external" } ], "gene_names_uniprotkb": "LOC100535728", "gene_names_refseq": "LOC100535728", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 46 isoform X1", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 46 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2V6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2W4-1", "uniprot_id": [ { "id": "A0AC58G2W4_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2W4", "type": "external" } ], "mass": 66798.0, "length": 592, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 46-like isoform X1", "gene_name": "LOC100535263", "organism": "Zebrafish", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 46-like isoform 2", "refseq_ac": [ { "id": "NP_001429827", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429827", "type": "external" } ], "gene_names_uniprotkb": "LOC100535263", "gene_names_refseq": "LOC100535263", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 46-like isoform X1", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 46-like isoform 2", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588728.37934864.1, SRR32588722.47253039.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN18715719, SAMN18715720 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2X9-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2Y1-1", "uniprot_id": [ { "id": "A0AC58G2Y1_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2Y1", "type": "external" } ], "mass": 42065.0, "length": 364, "protein_name": "C-type mannose receptor 2-like", "gene_name": "si:dkey-28d5.8", "organism": "Zebrafish", "refseq_name": "C-type mannose receptor 2-like", "refseq_ac": [ { "id": "XP_073764096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764096", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-28d5.8", "gene_names_refseq": "si:dkey-28d5.8", "protein_names_uniprotkb": "C-type mannose receptor 2-like", "protein_names_refseq": "C-type mannose receptor 2-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2Y6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2Y7-1", "uniprot_id": [ { "id": "A0AC58G2Y7_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2Y7", "type": "external" } ], "mass": 42023.0, "length": 364, "protein_name": "C-type mannose receptor 2-like", "gene_name": "LOC108179137", "organism": "Zebrafish", "refseq_name": "C-type mannose receptor 2-like", "refseq_ac": [ { "id": "XP_073764097", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764097", "type": "external" } ], "gene_names_uniprotkb": "LOC108179137", "gene_names_refseq": "LOC108179137", "protein_names_uniprotkb": "C-type mannose receptor 2-like", "protein_names_refseq": "C-type mannose receptor 2-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2Y7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2Y8-1", "uniprot_id": [ { "id": "A0AC58G2Y8_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2Y8", "type": "external" } ], "mass": 13608.0, "length": 124, "protein_name": "Histone H2B", "gene_name": "LOC141375023", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC554097", "refseq_ac": [ { "id": "NP_001019569", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019569", "type": "external" } ], "gene_names_uniprotkb": "LOC141375023; si:ch1073-159d7.6; si:ch73-368j24.10; si:ch73-368j24.8; si:ch73-368j24.9; si:dkey-23a13.16", "gene_names_refseq": "zgc:112234", "protein_names_uniprotkb": "Histone H2B", "protein_names_refseq": "uncharacterized protein LOC554097", "tax_id": 7955, "disease": "", "pathway": " (dre:100000857); (dre:100004810); (dre:100330556); (dre:100538106); (dre:564421); (dre:564549)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "12477932", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124434.1 [ECO:0000332] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. 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On Oct 29, 2006 this sequence version replaced NP_001019569.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046982 protein heterodimerization activity;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0000786 nucleosome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0AC58G2Y8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G302-1", "uniprot_id": [ { "id": "A0AC58G302_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G302", "type": "external" } ], "mass": 99417.0, "length": 899, "protein_name": "Phosphofurin acidic cluster sorting protein 1 isoform X1", "gene_name": "pacs1", "organism": "Zebrafish", "refseq_name": "phosphofurin acidic cluster sorting protein 1 isoform X1", "refseq_ac": [ { "id": "XP_073764107", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764107", "type": "external" } ], "gene_names_uniprotkb": "pacs1", "gene_names_refseq": "pacs1", "protein_names_uniprotkb": "Phosphofurin acidic cluster sorting protein 1 isoform X1", "protein_names_refseq": "phosphofurin acidic cluster sorting protein 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G302-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G2Z6-1", "uniprot_id": [ { "id": "A0AC58G2Z6_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G2Z6", "type": "external" } ], "mass": 41937.0, "length": 360, "protein_name": "LOW QUALITY PROTEIN: C-type mannose receptor 2", "gene_name": "si:dkey-28d5.7", "organism": "Zebrafish", "refseq_name": "LOW QUALITY PROTEIN: C-type mannose receptor 2", "refseq_ac": [ { "id": "XP_073764098", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764098", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-28d5.7", "gene_names_refseq": "si:dkey-28d5.7", "protein_names_uniprotkb": "LOW QUALITY PROTEIN: C-type mannose receptor 2", "protein_names_refseq": "LOW QUALITY PROTEIN: C-type mannose receptor 2", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G2Z6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G300-1", "uniprot_id": [ { "id": "A0AC58G300_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G300", "type": "external" } ], "mass": 129268.0, "length": 1139, "protein_name": "Uncharacterized protein isoform X2; Uncharacterized protein si:ch73-269m14.4 isoform X2", "gene_name": "LOC101882062", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch73-269m14.4 isoform X2", "refseq_ac": [ { "id": "XP_073791661", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073791661", "type": "external" } ], "gene_names_uniprotkb": "LOC101882062; si:ch73-269m14.4", "gene_names_refseq": "si:ch73-269m14.4", "protein_names_uniprotkb": "Uncharacterized protein isoform X2; Uncharacterized protein si:ch73-269m14.4 isoform X2", "protein_names_refseq": "uncharacterized protein si:ch73-269m14.4 isoform X2", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58IBQ8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G300-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G301-1", "uniprot_id": [ { "id": "A0AC58G301_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G301", "type": "external" } ], "mass": 38040.0, "length": 336, "protein_name": "Fc receptor-like protein 2", "gene_name": "LOC137496070", "organism": "Zebrafish", "refseq_name": "Fc receptor-like protein 2", "refseq_ac": [ { "id": "XP_073764101", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764101", "type": "external" } ], "gene_names_uniprotkb": "LOC137496070", "gene_names_refseq": "LOC137496070", "protein_names_uniprotkb": "Fc receptor-like protein 2", "protein_names_refseq": "Fc receptor-like protein 2", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G301-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G313-1", "uniprot_id": [ { "id": "A0AC58G313_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G313", "type": "external" } ], "mass": 83639.0, "length": 747, "protein_name": "Ras and Rab interactor 2 isoform X1", "gene_name": "rin1b", "organism": "Zebrafish", "refseq_name": "ras and Rab interactor 2 isoform X1", "refseq_ac": [ { "id": "XP_073764117", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764117", "type": "external" } ], "gene_names_uniprotkb": "rin1b", "gene_names_refseq": "rin1b", "protein_names_uniprotkb": "Ras and Rab interactor 2 isoform X1", "protein_names_refseq": "ras and Rab interactor 2 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G313-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G308-1", "uniprot_id": [ { "id": "A0AC58G308_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G308", "type": "external" } ], "mass": 39474.0, "length": 353, "protein_name": "Junctional adhesion molecule A-like isoform X1", "gene_name": "LOC110439918", "organism": "Zebrafish", "refseq_name": "junctional adhesion molecule A-like isoform X1", "refseq_ac": [ { "id": "XP_073764099", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764099", "type": "external" } ], "gene_names_uniprotkb": "LOC110439918", "gene_names_refseq": "LOC110439918", "protein_names_uniprotkb": "Junctional adhesion molecule A-like isoform X1", "protein_names_refseq": "junctional adhesion molecule A-like isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G308-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G314-1", "uniprot_id": [ { "id": "A0AC58G314_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G314", "type": "external" } ], "mass": 46832.0, "length": 420, "protein_name": "Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial", "gene_name": "aadat", "organism": "Zebrafish", "refseq_name": "kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_073764122", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764122", "type": "external" } ], "gene_names_uniprotkb": "aadat", "gene_names_refseq": "aadat", "protein_names_uniprotkb": "Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; 2.6.1.39; 2.6.1.4; 2.6.1.63; 2.6.1.73; 2.6.1.7; Alpha-aminoadipate aminotransferase; Glycine transaminase AADAT; Kynurenine aminotransferase II; Kynurenine--glyoxylate transaminase AADAT; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; Kynurenine--oxoglutarate transaminase II; Methionine--glyoxylate transaminase AADAT", "protein_names_refseq": "kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.4.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.13", "type": "external" }, { "id": "2.6.1.63", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.63", "type": "external" }, { "id": "2.6.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.7", "type": "external" }, { "id": "2.6.1.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.39", "type": "external" }, { "id": "2.6.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.4", "type": "external" }, { "id": "2.6.1.73", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.73", "type": "external" }, { "id": "2.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.1", "type": "external" } ], "go_molecular_function": "GO:0008483 transaminase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G314-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G323-1", "uniprot_id": [ { "id": "A0AC58G323_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G323", "type": "external" } ], "mass": 102439.0, "length": 893, "protein_name": "Protein NLRC3-like", "gene_name": "LOC141375289", "organism": "Zebrafish", "refseq_name": "protein NLRC3-like", "refseq_ac": [ { "id": "XP_073764142", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764142", "type": "external" } ], "gene_names_uniprotkb": "LOC141375289", "gene_names_refseq": "LOC141375289", "protein_names_uniprotkb": "Protein NLRC3-like", "protein_names_refseq": "protein NLRC3-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G323-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G337-1", "uniprot_id": [ { "id": "A0AC58G337_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G337", "type": "external" } ], "mass": 35200.0, "length": 320, "protein_name": "Aerolysin-like protein isoform X1", "gene_name": "LOC137496077", "organism": "Zebrafish", "refseq_name": "aerolysin-like protein isoform X1", "refseq_ac": [ { "id": "XP_073764129", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764129", "type": "external" } ], "gene_names_uniprotkb": "LOC137496077", "gene_names_refseq": "LOC137496077", "protein_names_uniprotkb": "Aerolysin-like protein isoform X1", "protein_names_refseq": "aerolysin-like protein isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G3K6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G3L0-1", "uniprot_id": [ { "id": "A0AC58G3L0_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G3L0", "type": "external" } ], "mass": 106762.0, "length": 954, "protein_name": "Uncharacterized protein isoform X2", "gene_name": "LOC141375328", "organism": "Zebrafish", "refseq_name": "uncharacterized protein isoform X2", "refseq_ac": [ { "id": "XP_073764327", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764327", "type": "external" } ], "gene_names_uniprotkb": "LOC141375328", "gene_names_refseq": "LOC141375328", "protein_names_uniprotkb": "Uncharacterized protein isoform X2", "protein_names_refseq": "uncharacterized protein isoform X2", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G3L0-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G3L1-1", "uniprot_id": [ { "id": "A0AC58G3L1_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G3L1", "type": "external" } ], "mass": 37421.0, "length": 335, "protein_name": "Uncharacterized protein nitr1k", "gene_name": "nitr1k", "organism": "Zebrafish", "refseq_name": "uncharacterized protein nitr1k", "refseq_ac": [ { "id": "XP_073764308", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764308", "type": "external" } ], "gene_names_uniprotkb": "nitr1k", "gene_names_refseq": "nitr1k", "protein_names_uniprotkb": "Uncharacterized protein nitr1k", "protein_names_refseq": "uncharacterized protein nitr1k", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G3L1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G3L2-1", "uniprot_id": [ { "id": "A0AC58G3L2_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G3L2", "type": "external" } ], "mass": 28546.0, "length": 249, "protein_name": "C-type lectin domain-containing protein", "gene_name": "si:busm1-169i8.11", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC446136 precursor", "refseq_ac": [ { "id": "NP_001018880", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018880", "type": "external" } ], "gene_names_uniprotkb": "si:busm1-169i8.11", "gene_names_refseq": "si:busm1-169i8.11; si:ch73-46n24.4", "protein_names_uniprotkb": "C-type lectin domain-containing protein", "protein_names_refseq": "lectin C-type domain containing protein; uncharacterized protein LOC446136 precursor", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On or before Sep 23, 2025 this sequence version replaced XP_073764316.1, NP_001018880.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G3L2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G3L3-1", "uniprot_id": [ { "id": "A0AC58G3L3_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G3L3", "type": "external" } ], "mass": 27369.0, "length": 243, "protein_name": "Novel immune-type receptor 7b", "gene_name": "nitr7b", "organism": "Zebrafish", "refseq_name": "novel immune-type receptor 7b precursor", "refseq_ac": [ { "id": "NP_001005578", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005578", "type": "external" } ], "gene_names_uniprotkb": "nitr7b", "gene_names_refseq": "nitr7.1; nitr7.4; nitr7.5; nitr7.6; nitr7.8; nitr7b_2; nitr7b_3; nitr7b_4; nitr7b", "protein_names_uniprotkb": "Novel immune-type receptor 7b", "protein_names_refseq": "novel immune-type receptor 7b precursor", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AY570235.1, GDQH01017171.1 [ECO:0000332] RNAseq introns :: partial sample support SAMN01765705, SAMN08196788 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On or before Jun 24, 2025 this sequence version replaced XP_073764317.1, NP_001005578.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G3L3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G3L8-1", "uniprot_id": [ { "id": "A0AC58G3L8_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G3L8", "type": "external" } ], "mass": 108800.0, "length": 956, "protein_name": "Protein NLRC3-like", "gene_name": "LOC103908614", "organism": "Zebrafish", "refseq_name": "protein NLRC3-like", "refseq_ac": [ { "id": "XP_073764322", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764322", "type": "external" } ], "gene_names_uniprotkb": "LOC103908614", "gene_names_refseq": "LOC103908614", "protein_names_uniprotkb": "Protein NLRC3-like", "protein_names_refseq": "protein NLRC3-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G3L8-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G3L9-1", "uniprot_id": [ { "id": "A0AC58G3L9_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G3L9", "type": "external" } ], "mass": 27025.0, "length": 240, "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC137496253", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_073764320", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764320", "type": "external" } ], "gene_names_uniprotkb": "LOC137496253", "gene_names_refseq": "LOC137496253", "protein_names_uniprotkb": "Ig-like domain-containing protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. 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This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. 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The reference sequence was derived from JBMGRA010000001.1. On Aug 29, 2025 this sequence version replaced XP_073764514.1., [RefSeq]", "predicted_glycosites": 28, "predicted_n_glycosites": 0, "predicted_o_glycosites": 28, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 28, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G479-1", "record_type": "protein", "filter_code": "0000000.0000000.000010.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G481-1", "uniprot_id": [ { "id": "A0AC58G481_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G481", "type": "external" } ], "mass": 139659.0, "length": 1349, "protein_name": "Uncharacterized protein si:ch211-196f2.3", "gene_name": "si:ch211-196f2.3", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:ch211-196f2.3", "refseq_ac": [ { "id": "XP_073764533", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764533", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-196f2.3", "gene_names_refseq": "si:ch211-196f2.3", "protein_names_uniprotkb": "Uncharacterized protein si:ch211-196f2.3", "protein_names_refseq": "uncharacterized protein si:ch211-196f2.3", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G481-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G4G9-1", "uniprot_id": [ { "id": "A0AC58G4G9_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G4G9", "type": "external" } ], "mass": 59083.0, "length": 521, "protein_name": "Uncharacterized protein", "gene_name": "LOC110438773", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_073764627", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764627", "type": "external" } ], "gene_names_uniprotkb": "LOC110438773", "gene_names_refseq": "LOC110438773", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G4G9-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G4J4-1", "uniprot_id": [ { "id": "A0AC58G4J4_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G4J4", "type": "external" } ], "mass": 57183.0, "length": 503, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC137490677", "organism": "Zebrafish", "refseq_name": "serine/threonine-protein kinase pim-2-like", "refseq_ac": [ { "id": "XP_073764648", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764648", "type": "external" } ], "gene_names_uniprotkb": "LOC137490677", "gene_names_refseq": "LOC137490677", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase pim-2-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G4J4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G4K0-1", "uniprot_id": [ { "id": "A0AC58G4K0_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G4K0", "type": "external" } ], "mass": 36852.0, "length": 320, "protein_name": "G-protein coupled receptor 4-like", "gene_name": "LOC141375374", "organism": "Zebrafish", "refseq_name": "G-protein coupled receptor 4-like", "refseq_ac": [ { "id": "XP_073764659", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073764659", "type": "external" } ], "gene_names_uniprotkb": "LOC141375374", "gene_names_refseq": "LOC141375374", "protein_names_uniprotkb": "G-protein coupled receptor 4-like", "protein_names_refseq": "G-protein coupled receptor 4-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by mRNA evidence. 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This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G5Q4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G5Q1-1", "uniprot_id": [ { "id": "A0AC58G5Q1_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G5Q1", "type": "external" } ], "mass": 69139.0, "length": 621, "protein_name": "Acyl-CoA dehydrogenase family member 11-like", "gene_name": "LOC101884216", "organism": "Zebrafish", "refseq_name": "acyl-CoA dehydrogenase family member 11-like", "refseq_ac": [ { "id": "XP_073765065", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765065", "type": "external" } ], "gene_names_uniprotkb": "LOC101884216", "gene_names_refseq": "LOC101884216", "protein_names_uniprotkb": "Acyl-CoA dehydrogenase family member 11-like", "protein_names_refseq": "acyl-CoA dehydrogenase family member 11-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58G5R1;A0AC58G5R3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G5Q1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G5R4-1", "uniprot_id": [ { "id": "A0AC58G5R4_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G5R4", "type": "external" } ], "mass": 14931.0, "length": 136, "protein_name": "Ly6/PLAUR domain-containing protein 1", "gene_name": "zgc:92827", "organism": "Zebrafish", "refseq_name": "ly6/PLAUR domain-containing protein 1", "refseq_ac": [ { "id": "XP_073765076", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765076", "type": "external" } ], "gene_names_uniprotkb": "zgc:92827", "gene_names_refseq": "zgc:92827", "protein_names_uniprotkb": "Ly6/PLAUR domain-containing protein 1", "protein_names_refseq": "ly6/PLAUR domain-containing protein 1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G5R4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G5R8-1", "uniprot_id": [ { "id": "A0AC58G5R8_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G5R8", "type": "external" } ], "mass": 114186.0, "length": 1026, "protein_name": "Uncharacterized protein", "gene_name": "LOC141375500", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_073765079", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765079", "type": "external" } ], "gene_names_uniprotkb": "LOC141375500", "gene_names_refseq": "LOC141375500", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G5R8-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G5T6-1", "uniprot_id": [ { "id": "A0AC58G5T6_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G5T6", "type": "external" } ], "mass": 67728.0, "length": 610, "protein_name": "Uncharacterized protein", "gene_name": "LOC101884693", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_073765089", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765089", "type": "external" } ], "gene_names_uniprotkb": "LOC101884693", "gene_names_refseq": "LOC101884693", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G5T6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G5U6-1", "uniprot_id": [ { "id": "A0AC58G5U6_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G5U6", "type": "external" } ], "mass": 97328.0, "length": 876, "protein_name": "Potassium voltage-gated channel, KQT-like subfamily, member 2a isoform X1", "gene_name": "kcnq2a", "organism": "Zebrafish", "refseq_name": "potassium voltage-gated channel, KQT-like subfamily, member 2a isoform 1", "refseq_ac": [ { "id": "NP_001429544", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429544", "type": "external" } ], "gene_names_uniprotkb": "kcnq2a; zgc:171872", "gene_names_refseq": "kcnq2a; zgc:171872", "protein_names_uniprotkb": "Potassium voltage-gated channel, KQT-like subfamily, member 2a isoform X1", "protein_names_refseq": "potassium voltage-gated channel, KQT-like subfamily, member 2a isoform 1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588718.10874749.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On Aug 15, 2025 this sequence version replaced XP_073765113.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.2", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G5U6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G5V6-1", "uniprot_id": [ { "id": "A0AC58G5V6_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G5V6", "type": "external" } ], "mass": 62784.0, "length": 560, "protein_name": "Uncharacterized protein F54H12.2-like", "gene_name": "LOC141375502", "organism": "Zebrafish", "refseq_name": "uncharacterized protein F54H12.2-like", "refseq_ac": [ { "id": "XP_073765111", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765111", "type": "external" } ], "gene_names_uniprotkb": "LOC141375502", "gene_names_refseq": "LOC141375502", "protein_names_uniprotkb": "Uncharacterized protein F54H12.2-like", "protein_names_refseq": "uncharacterized protein F54H12.2-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 100% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G5V6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G5X3-1", "uniprot_id": [ { "id": "A0AC58G5X3_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G5X3", "type": "external" } ], "mass": 179698.0, "length": 1534, "protein_name": "Uncharacterized protein", "gene_name": "LOC137495322", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_073765133", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765133", "type": "external" } ], "gene_names_uniprotkb": "LOC137495322", "gene_names_refseq": "LOC137495322", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G5X3-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G5Y4-1", "uniprot_id": [ { "id": "A0AC58G5Y4_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G5Y4", "type": "external" } ], "mass": 40947.0, "length": 343, "protein_name": "Carbohydrate sulfotransferase", "gene_name": "chst12b.6", "organism": "Zebrafish", "refseq_name": "carbohydrate sulfotransferase 12-like", "refseq_ac": [ { "id": "XP_073765141", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765141", "type": "external" } ], "gene_names_uniprotkb": "chst12b.6", "gene_names_refseq": "chst12b.6", "protein_names_uniprotkb": "Carbohydrate sulfotransferase; 2.8.2.-", "protein_names_refseq": "carbohydrate sulfotransferase 12-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G5Y4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G617-1", "uniprot_id": [ { "id": "A0AC58G617_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G617", "type": "external" } ], "mass": 13548.0, "length": 118, "protein_name": "DWNN domain-containing protein isoform X1", "gene_name": "LOC100535522", "organism": "Zebrafish", "refseq_name": "DWNN domain-containing protein isoform X1", "refseq_ac": [ { "id": "XP_073765172", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765172", "type": "external" } ], "gene_names_uniprotkb": "LOC100535522", "gene_names_refseq": "LOC100535522", "protein_names_uniprotkb": "DWNN domain-containing protein isoform X1", "protein_names_refseq": "DWNN domain-containing protein isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G617-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G619-1", "uniprot_id": [ { "id": "A0AC58G619_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G619", "type": "external" } ], "mass": 42671.0, "length": 388, "protein_name": "Si:ch73-236j9.2 isoform X1", "gene_name": "si:ch73-236j9.2", "organism": "Zebrafish", "refseq_name": "si:ch73-236j9.2 isoform X1", "refseq_ac": [ { "id": "XP_073765181", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765181", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-236j9.2", "gene_names_refseq": "si:ch73-236j9.2", "protein_names_uniprotkb": "Si:ch73-236j9.2 isoform X1", "protein_names_refseq": "si:ch73-236j9.2 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "27189481", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Putative transporter., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58G632", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0AC58G619-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G626-1", "uniprot_id": [ { "id": "A0AC58G626_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G626", "type": "external" } ], "mass": 12319.0, "length": 106, "protein_name": "CD209 antigen-like protein A", "gene_name": "LOC141375506", "organism": "Zebrafish", "refseq_name": "CD209 antigen-like protein A", "refseq_ac": [ { "id": "XP_073765185", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765185", "type": "external" } ], "gene_names_uniprotkb": "LOC141375506", "gene_names_refseq": "LOC141375506", "protein_names_uniprotkb": "CD209 antigen-like protein A", "protein_names_refseq": "CD209 antigen-like protein A", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: incomplete on the amino end., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G645-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6G7-1", "uniprot_id": [ { "id": "A0ACD6B6G7_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6G7", "type": "external" } ], "mass": 66185.0, "length": 579, "protein_name": "Cryptochrome circadian regulator 4 isoform X1", "gene_name": "cry4", "organism": "Zebrafish", "refseq_name": "cryptochrome circadian regulator 4 isoform X1", "refseq_ac": [ { "id": "XP_005168334", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168334", "type": "external" } ], "gene_names_uniprotkb": "cry4; fi23e01; wu:fi23e01; zcry4", "gene_names_refseq": "cry4; fi23e01; wu:fi23e01; zcry4", "protein_names_uniprotkb": "Cryptochrome circadian regulator 4 isoform X1", "protein_names_refseq": "cryptochrome circadian regulator 4 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005168334.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0009881 photoreceptor activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6G7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5W0-1", "uniprot_id": [ { "id": "A0ACD6B5W0_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5W0", "type": "external" } ], "mass": 225578.0, "length": 1974, "protein_name": "Unconventional myosin-IXb isoform X1", "gene_name": "myo9b", "organism": "Zebrafish", "refseq_name": "unconventional myosin-IXb isoform X1", "refseq_ac": [ { "id": "XP_005171391", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171391", "type": "external" } ], "gene_names_uniprotkb": "myo9b", "gene_names_refseq": "myo9b", "protein_names_uniprotkb": "Unconventional myosin-IXb isoform X1", "protein_names_refseq": "unconventional myosin-IXb isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005171391.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005096 GTPase activator activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016459 myosin complex", "go_biological_process": "GO:0048731 system development;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5W0-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5T8-1", "uniprot_id": [ { "id": "A0ACD6B5T8_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5T8", "type": "external" } ], "mass": 126374.0, "length": 1119, "protein_name": "adenylate cyclase", "gene_name": "adcy3a", "organism": "Zebrafish", "refseq_name": "adenylate cyclase type 3 isoform X1", "refseq_ac": [ { "id": "XP_009290286", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290286", "type": "external" } ], "gene_names_uniprotkb": "adcy3a; adcy3l; adcy3", "gene_names_refseq": "adcy3a; adcy3l; adcy3", "protein_names_uniprotkb": "adenylate cyclase; 4.6.1.1", "protein_names_refseq": "adenylate cyclase type 3 isoform X1", "tax_id": 7955, "disease": "major depressive disorder (Disease Ontology:DOID:1470)", "pathway": " (dre:571825)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "26469318;27189481;28252024;36430661", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009290286.1. COMPLETENESS: full length., [RefSeq]; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.1", "type": "external" }, { "id": "2.7.7.85", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.85", "type": "external" } ], "go_molecular_function": "GO:0004016 adenylate cyclase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005929 cilium", "go_biological_process": "GO:0006171 cAMP biosynthetic process;GO:0035556 intracellular signal transduction;GO:0007608 sensory perception of smell;GO:0032400 melanosome localization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0ACD6B5T8-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5Y1-1", "uniprot_id": [ { "id": "A0ACD6B5Y1_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5Y1", "type": "external" } ], "mass": 85152.0, "length": 770, "protein_name": "Serine/threonine-protein kinase DCLK2", "gene_name": "dclk1a", "organism": "Zebrafish", "refseq_name": "serine/threonine-protein kinase DCLK1a isoform X1", "refseq_ac": [ { "id": "XP_073770142", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073770142", "type": "external" } ], "gene_names_uniprotkb": "dclk1a; dcamkl1; dclk1; wu:fc51f11; zgc:153709", "gene_names_refseq": "dcamkl1; dclk1a; dclk1; wu:fc51f11; zgc:153709", "protein_names_uniprotkb": "Serine/threonine-protein kinase DCLK2; 2.7.11.1; CaMK-like CREB regulatory kinase 2; Doublecortin-like and CAM kinase-like 2; Doublecortin-like kinase 2", "protein_names_refseq": "serine/threonine-protein kinase DCLK1a isoform X1", "tax_id": 7955, "disease": "dyslexia (Disease Ontology:DOID:4428)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58GK97", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0016301 kinase activity", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005737 cytoplasm;GO:0043005 neuron projection", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0007417 central nervous system development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5Y1-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6S4-1", "uniprot_id": [ { "id": "A0ACD6B6S4_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6S4", "type": "external" } ], "mass": 66618.0, "length": 606, "protein_name": "BAR/IMD domain-containing adapter protein 2", "gene_name": "zgc:158689", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC791177", "refseq_ac": [ { "id": "NP_001315317", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315317", "type": "external" } ], "gene_names_uniprotkb": "zgc:158689", "gene_names_refseq": "zgc:158689", "protein_names_uniprotkb": "BAR/IMD domain-containing adapter protein 2; Brain-specific angiogenesis inhibitor 1-associated protein 2", "protein_names_refseq": "uncharacterized protein LOC791177", "tax_id": 7955, "disease": "", "pathway": " (dre:791177)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "26469318;28252024", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588724.3296320.1, SRR32588714.8808252.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476739, SAMEA4476740 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Jun 17, 2025 this sequence version replaced NP_001315317.1., [RefSeq]; Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008093 cytoskeletal anchor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0016020 membrane;GO:0030175 filopodium", "go_biological_process": "GO:0007009 plasma membrane organization;GO:0051017 actin filament bundle assembly;GO:0030182 neuron differentiation;GO:0051764 actin crosslink formation;GO:0030838 positive regulation of actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0ACD6B6S4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B667-1", "uniprot_id": [ { "id": "A0ACD6B667_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B667", "type": "external" } ], "mass": 63591.0, "length": 564, "protein_name": "Lysyl oxidase homolog", "gene_name": "loxl5b", "organism": "Zebrafish", "refseq_name": "lysyl oxidase-like 5b isoform X1", "refseq_ac": [ { "id": "XP_017212858", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212858", "type": "external" } ], "gene_names_uniprotkb": "loxl5b", "gene_names_refseq": "loxl5b", "protein_names_uniprotkb": "Lysyl oxidase homolog; 1.4.3.13", "protein_names_refseq": "lysyl oxidase-like 5b isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017212858.1. COMPLETENESS: full length., [RefSeq]; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.4.3.13", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.13", "type": "external" }, { "id": "1.4.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.-", "type": "external" } ], "go_molecular_function": "GO:0005507 copper ion binding;GO:0004720 protein-lysine 6-oxidase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0048570 notochord morphogenesis;GO:0030903 notochord development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B667-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B606-1", "uniprot_id": [ { "id": "A0ACD6B606_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B606", "type": "external" } ], "mass": 110010.0, "length": 1011, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "ulk1b", "organism": "Zebrafish", "refseq_name": "serine/threonine-protein kinase ULK1 isoform X1", "refseq_ac": [ { "id": "XP_002665971", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002665971", "type": "external" } ], "gene_names_uniprotkb": "ulk1b", "gene_names_refseq": "ulk1b", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase ULK1 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_002665971.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0016301 kinase activity", "go_cellular_component": "GO:0034045 phagophore assembly site membrane", "go_biological_process": "GO:0010506 regulation of autophagy;GO:0006914 autophagy", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B606-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B764-1", "uniprot_id": [ { "id": "A0ACD6B764_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B764", "type": "external" } ], "mass": 99655.0, "length": 886, "protein_name": "Serine/threonine-protein kinase", "gene_name": "prkd1", "organism": "Zebrafish", "refseq_name": "serine/threonine-protein kinase D1 isoform X1", "refseq_ac": [ { "id": "XP_005158873", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005158873", "type": "external" } ], "gene_names_uniprotkb": "prkd1", "gene_names_refseq": "prkd1", "protein_names_uniprotkb": "Serine/threonine-protein kinase; 2.7.11.13", "protein_names_refseq": "serine/threonine-protein kinase D1 isoform X1", "tax_id": 7955, "disease": "congenital heart disease (Disease Ontology:DOID:1682)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005158873.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0004697 diacylglycerol-dependent serine/threonine kinase activity;GO:0016301 kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0045765 regulation of angiogenesis;GO:1901490 regulation of lymphangiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B764-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6H7-1", "uniprot_id": [ { "id": "A0ACD6B6H7_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6H7", "type": "external" } ], "mass": 90816.0, "length": 805, "protein_name": "Lethal(3)malignant brain tumor-like protein 2", "gene_name": "l3mbtl2", "organism": "Zebrafish", "refseq_name": "lethal(3)malignant brain tumor-like protein 2 isoform X1", "refseq_ac": [ { "id": "XP_073773949", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073773949", "type": "external" } ], "gene_names_uniprotkb": "l3mbtl2; im:7137244; wu:fb04e09; zgc:66491", "gene_names_refseq": "im:7137244; l3mbtl2; wu:fb04e09; zgc:66491", "protein_names_uniprotkb": "Lethal(3)malignant brain tumor-like protein 2", "protein_names_refseq": "lethal(3)malignant brain tumor-like protein 2 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58GW62", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0006351 DNA-templated transcription;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6H7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6J4-1", "uniprot_id": [ { "id": "A0ACD6B6J4_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6J4", "type": "external" } ], "mass": 85051.0, "length": 761, "protein_name": "C3/C5 convertase", "gene_name": "cfb", "organism": "Zebrafish", "refseq_name": "complement factor B isoform X1", "refseq_ac": [ { "id": "XP_021324426", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324426", "type": "external" } ], "gene_names_uniprotkb": "cfb; Bf-1; Brre-Bf; bf; zgc:114032", "gene_names_refseq": "Bf-1; Brre-Bf; bf; cfb; zgc:114032", "protein_names_uniprotkb": "C3/C5 convertase", "protein_names_refseq": "complement factor B isoform X1", "tax_id": 7955, "disease": "sinusitis (Disease Ontology:DOID:0050127); lupus nephritis (Disease Ontology:DOID:0080162); atypical hemolytic-uremic syndrome (Disease Ontology:DOID:0080301); erythema nodosum (Disease Ontology:DOID:0080750); age related macular degeneration 14 (Disease Ontology:DOID:0110026); lepromatous leprosy (Disease Ontology:DOID:10887); sickle cell anemia (Disease Ontology:DOID:10923); membranous glomerulonephritis (Disease Ontology:DOID:10976); pyelonephritis (Disease Ontology:DOID:11400); factor VIII deficiency (Disease Ontology:DOID:12134); beta thalassemia (Disease Ontology:DOID:12241); paracoccidioidomycosis (Disease Ontology:DOID:12662); Behcet's disease (Disease Ontology:DOID:13241); anterior uveitis (Disease Ontology:DOID:1407); boutonneuse fever (Disease Ontology:DOID:14095); breast cancer (Disease Ontology:DOID:1612); membranoproliferative glomerulonephritis (Disease Ontology:DOID:2920); IgA glomerulonephritis (Disease Ontology:DOID:2986); systemic scleroderma (Disease Ontology:DOID:418); macular degeneration (Disease Ontology:DOID:4448); conjunctivitis (Disease Ontology:DOID:6195); end stage renal disease (Disease Ontology:DOID:783); psoriasis (Disease Ontology:DOID:8893); diabetic retinopathy (Disease Ontology:DOID:8947); autosomal dominant polycystic kidney disease (Disease Ontology:DOID:898); type 1 diabetes mellitus (Disease Ontology:DOID:9744); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dre:30604)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10207156;16109975;16630661;16631158;34185526;36248846;36736605;36948605;38927252;9794413", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021324426.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 27, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0009986 cell surface", "go_biological_process": "GO:0006508 proteolysis;GO:0006955 immune response;GO:0045087 innate immune response;GO:0009617 response to bacterium;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "A0ACD6B6J4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B614-1", "uniprot_id": [ { "id": "A0ACD6B614_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B614", "type": "external" } ], "mass": 168543.0, "length": 1506, "protein_name": "Kinesin-like protein KIF14", "gene_name": "kif14", "organism": "Zebrafish", "refseq_name": "kinesin-like protein KIF14 isoform X1", "refseq_ac": [ { "id": "XP_005170522", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170522", "type": "external" } ], "gene_names_uniprotkb": "kif14; si:dkey-39e8.3; wu:fi16h07", "gene_names_refseq": "kif14; si:dkey-39e8.3; wu:fi16h07", "protein_names_uniprotkb": "Kinesin-like protein KIF14", "protein_names_refseq": "kinesin-like protein KIF14 isoform X1", "tax_id": 7955, "disease": "Meckel syndrome (Disease Ontology:DOID:0050778); primary autosomal recessive microcephaly 20 (Disease Ontology:DOID:0051031)", "pathway": " (dre:562052)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "30388224;31291987;31451657", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005170522.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005819 spindle;GO:0005874 microtubule;GO:0030496 midbody", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0001822 kidney development;GO:0007420 brain development;GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0ACD6B614-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G6C1-1", "uniprot_id": [ { "id": "A0AC58G6C1_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G6C1", "type": "external" } ], "mass": 97827.0, "length": 884, "protein_name": "Cold shock domain-containing protein E1", "gene_name": "csde1", "organism": "Zebrafish", "refseq_name": "cold shock domain-containing protein E1 isoform X1", "refseq_ac": [ { "id": "XP_073765273", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765273", "type": "external" } ], "gene_names_uniprotkb": "csde1; fa92c07; si:ch211-261n11.2; wu:fa92c07; wu:fa97c10; wu:fb53f07; wu:fb78d03", "gene_names_refseq": "csde1; fa92c07; si:ch211-261n11.2; wu:fa92c07; wu:fa97c10; wu:fb53f07; wu:fb78d03", "protein_names_uniprotkb": "Cold shock domain-containing protein E1", "protein_names_refseq": "cold shock domain-containing protein E1 isoform X1", "tax_id": 7955, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041)", "pathway": " (dre:336679)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "26469318;28173755;30174136;30692167;31562209;40044042", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; RNA-binding protein involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Required for efficient formation of stress granules., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1905172 RISC complex binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0000932 P-body;GO:0010494 cytoplasmic stress granule", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0AC58G6C1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G7T5-1", "uniprot_id": [ { "id": "A0AC58G7T5_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G7T5", "type": "external" } ], "mass": 64940.0, "length": 585, "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1", "gene_name": "tab3", "organism": "Zebrafish", "refseq_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1", "refseq_ac": [ { "id": "XP_073765798", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765798", "type": "external" } ], "gene_names_uniprotkb": "tab3; map3k7ip3l; map3k7ip3; si:ch211-232d19.8; si:dkey-30h22.6", "gene_names_refseq": "map3k7ip3l; map3k7ip3; si:ch211-232d19.8; si:dkey-30h22.6; tab3", "protein_names_uniprotkb": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1", "protein_names_refseq": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1", "tax_id": 7955, "disease": "rheumatoid arthritis (Disease Ontology:DOID:7148); systemic lupus erythematosus (Disease Ontology:DOID:9074)", "pathway": " (dre:566547)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "18039395;24714733;26469318;26818140;27189481", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016301 kinase activity;GO:0043130 ubiquitin binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0AC58G7T5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6G0-1", "uniprot_id": [ { "id": "A0ACD6B6G0_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6G0", "type": "external" } ], "mass": 130398.0, "length": 1157, "protein_name": "Pleckstrin homology domain-containing family G member 5 isoform X1", "gene_name": "plekhg5a", "organism": "Zebrafish", "refseq_name": "pleckstrin homology domain-containing family G member 5 isoform X1", "refseq_ac": [ { "id": "XP_009304320", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304320", "type": "external" } ], "gene_names_uniprotkb": "plekhg5a", "gene_names_refseq": "plekhg5a", "protein_names_uniprotkb": "Pleckstrin homology domain-containing family G member 5 isoform X1", "protein_names_refseq": "pleckstrin homology domain-containing family G member 5 isoform X1", "tax_id": 7955, "disease": "Charcot-Marie-Tooth disease recessive intermediate C (Disease Ontology:DOID:0110198); autosomal recessive distal hereditary motor neuronopathy 4 (Disease Ontology:DOID:0111213)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009304320.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0042995 cell projection", "go_biological_process": "GO:0001525 angiogenesis;GO:0043534 blood vessel endothelial cell migration;GO:0007369 gastrulation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6G0-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6F6-1", "uniprot_id": [ { "id": "A0ACD6B6F6_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6F6", "type": "external" } ], "mass": 81784.0, "length": 738, "protein_name": "Platelet endothelial cell adhesion molecule", "gene_name": "pecam1a", "organism": "Zebrafish", "refseq_name": "platelet endothelial cell adhesion molecule isoform X1", "refseq_ac": [ { "id": "XP_005164330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005164330", "type": "external" } ], "gene_names_uniprotkb": "pecam1a; CD31; pecam1; zmp:0000000686", "gene_names_refseq": "CD31; pecam1a; pecam1; zmp:0000000686", "protein_names_uniprotkb": "Platelet endothelial cell adhesion molecule", "protein_names_refseq": "platelet endothelial cell adhesion molecule isoform X1", "tax_id": 7955, "disease": "pterygium (Disease Ontology:DOID:0002116); chronic venous insufficiency (Disease Ontology:DOID:0050853); sickle cell anemia (Disease Ontology:DOID:10923); polycystic ovary syndrome (Disease Ontology:DOID:11612); common variable immunodeficiency (Disease Ontology:DOID:12177); autistic disorder (Disease Ontology:DOID:12849); eosinophilic esophagitis (Disease Ontology:DOID:13922); atherosclerosis (Disease Ontology:DOID:1936); ovarian cancer (Disease Ontology:DOID:2394); severe acute respiratory syndrome (Disease Ontology:DOID:2945); neurilemmoma (Disease Ontology:DOID:3192); coronary artery disease (Disease Ontology:DOID:3393); lung non-small cell carcinoma (Disease Ontology:DOID:3908); systemic scleroderma (Disease Ontology:DOID:418); coronary stenosis (Disease Ontology:DOID:4248); liver cirrhosis (Disease Ontology:DOID:5082); myocardial infarction (Disease Ontology:DOID:5844); neuroblastoma (Disease Ontology:DOID:769); varicose veins (Disease Ontology:DOID:799); polymyalgia rheumatica (Disease Ontology:DOID:853); chronic myeloid leukemia (Disease Ontology:DOID:8552); myeloid leukemia (Disease Ontology:DOID:8692); psoriatic arthritis (Disease Ontology:DOID:9008); babesiosis (Disease Ontology:DOID:9643)", "pathway": " (dre:569386)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "24247081;26469318;26952986;27156384;27581547;34931661;35417696;36536484;37196825;39213451", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005164330.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 24, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "A0ACD6B6F6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6K7-1", "uniprot_id": [ { "id": "A0ACD6B6K7_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6K7", "type": "external" } ], "mass": 53282.0, "length": 469, "protein_name": "Homeobox-containing protein 1", "gene_name": "zgc:91944", "organism": "Zebrafish", "refseq_name": "uncharacterized protein isoform X1", "refseq_ac": [ { "id": "XP_005159668", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005159668", "type": "external" } ], "gene_names_uniprotkb": "zgc:91944", "gene_names_refseq": "zgc:91944", "protein_names_uniprotkb": "Homeobox-containing protein 1", "protein_names_refseq": "uncharacterized protein isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005159668.1. COMPLETENESS: full length., [RefSeq]; Binds directly to 5'-TTAGGG-3' repeats in telomeric DNA. Associates with the telomerase complex at sites of active telomere processing and positively regulates telomere elongation. Important for TERT binding to chromatin, indicating a role in recruitment of the telomerase complex to telomeres. Also plays a role in the alternative lengthening of telomeres (ALT) pathway in telomerase-negative cells where it promotes formation and/or maintenance of ALT-associated promyelocytic leukemia bodies (APBs). Enhances formation of telomere C-circles in ALT cells, suggesting a possible role in telomere recombination. Might also be involved in the DNA damage response at telomeres., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0003691 double-stranded telomeric DNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016605 PML body;GO:0015030 Cajal body;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0007004 telomere maintenance via telomerase", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6K7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6T9-1", "uniprot_id": [ { "id": "A0ACD6B6T9_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6T9", "type": "external" } ], "mass": 151955.0, "length": 1401, "protein_name": "Palladin", "gene_name": "palld", "organism": "Zebrafish", "refseq_name": "palladin isoform X1", "refseq_ac": [ { "id": "XP_021324295", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324295", "type": "external" } ], "gene_names_uniprotkb": "palld", "gene_names_refseq": "palld", "protein_names_uniprotkb": "Palladin", "protein_names_refseq": "palladin isoform X1", "tax_id": 7955, "disease": "pancreatic cancer (Disease Ontology:DOID:1793); pancreatic ductal carcinoma (Disease Ontology:DOID:3587)", "pathway": " (dre:557660)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021324295.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding", "go_cellular_component": "GO:0005925 focal adhesion;GO:0030027 lamellipodium;GO:0030426 growth cone;GO:0002102 podosome;GO:0001725 stress fiber", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6T9-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G7Y6-1", "uniprot_id": [ { "id": "A0AC58G7Y6_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G7Y6", "type": "external" } ], "mass": 71107.0, "length": 627, "protein_name": "Uncharacterized protein isoform X1", "gene_name": "zgc:174931", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "zgc:174931; zgc:174931", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein isoform X1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:569527); (R-DRE-5656169)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "27189481", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0AC58G7Y6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G7R1-1", "uniprot_id": [ { "id": "A0AC58G7R1_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G7R1", "type": "external" } ], "mass": 49791.0, "length": 454, "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "rad9b", "organism": "Zebrafish", "refseq_name": "cell cycle checkpoint control protein RAD9B isoform X1", "refseq_ac": [ { "id": "XP_073765760", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765760", "type": "external" } ], "gene_names_uniprotkb": "rad9b; rad9a", "gene_names_refseq": "rad9a; rad9b", "protein_names_uniprotkb": "Cell cycle checkpoint control protein RAD9A; 3.1.11.2; DNA repair exonuclease rad9 homolog A", "protein_names_refseq": "cell cycle checkpoint control protein RAD9B isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:563903); (R-DRE-176187); (R-DRE-5685938); (R-DRE-5693607); (R-DRE-6804756); (R-DRE-69473)", "pathway_count": 6, "publication_count": 4, "publication_id_list": "18629171;27189481;27806088;34390914", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. RAD9A possesses 3'->5' double stranded DNA exonuclease activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008311 double-stranded DNA 3'-5' DNA exonuclease activity", "go_cellular_component": "GO:0030896 checkpoint clamp complex", "go_biological_process": "GO:0000077 DNA damage checkpoint signaling;GO:0000076 DNA replication checkpoint signaling;GO:0006281 DNA repair;GO:0071479 cellular response to ionizing radiation;GO:0031573 mitotic intra-S DNA damage checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0AC58G7R1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G7W9-1", "uniprot_id": [ { "id": "A0AC58G7W9_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G7W9", "type": "external" } ], "mass": 70347.0, "length": 623, "protein_name": "Copine Va isoform X1", "gene_name": "cpne5a", "organism": "Zebrafish", "refseq_name": "copine Va isoform X1", "refseq_ac": [ { "id": "XP_073765829", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765829", "type": "external" } ], "gene_names_uniprotkb": "cpne5a; si:ch211-180j19.1", "gene_names_refseq": "cpne5a; si:ch211-180j19.1", "protein_names_uniprotkb": "Copine Va isoform X1", "protein_names_refseq": "copine Va isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:568003)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "27189481;28252024", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0005544 calcium-dependent phospholipid binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0AC58G7W9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7B6-1", "uniprot_id": [ { "id": "A0ACD6B7B6_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7B6", "type": "external" } ], "mass": 139814.0, "length": 1293, "protein_name": "Protein transport protein Sec24C isoform X1", "gene_name": "sec24c", "organism": "Zebrafish", "refseq_name": "protein transport protein Sec24C isoform 2", "refseq_ac": [ { "id": "NP_001428493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428493", "type": "external" } ], "gene_names_uniprotkb": "sec24c; im:7145364; wu:fd10d12", "gene_names_refseq": "im:7145364; sec24c; wu:fd10d12", "protein_names_uniprotkb": "Protein transport protein Sec24C isoform X1", "protein_names_refseq": "SEC24 family, member C; SEC24-related protein C; protein transport protein Sec24C isoform 2", "tax_id": 7955, "disease": "", "pathway": " (dre:571870)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "20442775;21729877;24627348", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588723.3617100.1, SRR32588727.620261.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1. On Jun 17, 2025 this sequence version replaced XP_005156414.3., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane;GO:0030127 COPII vesicle coat", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0021549 cerebellum development;GO:0036438 maintenance of lens transparency;GO:0001966 thigmotaxis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0ACD6B7B6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G7V2-1", "uniprot_id": [ { "id": "A0AC58G7V2_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G7V2", "type": "external" } ], "mass": 83059.0, "length": 747, "protein_name": "Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma b isoform X1", "gene_name": "pip5k1cb", "organism": "Zebrafish", "refseq_name": "phosphatidylinositol-4-phosphate 5-kinase, type I, gamma b isoform X1", "refseq_ac": [ { "id": "XP_073765804", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765804", "type": "external" } ], "gene_names_uniprotkb": "pip5k1cb; si:ch211-117a23.4; si:ch211-243a15.1", "gene_names_refseq": "pip5k1cb; si:ch211-117a23.4; si:ch211-243a15.1", "protein_names_uniprotkb": "Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma b isoform X1", "protein_names_refseq": "phosphatidylinositol-4-phosphate 5-kinase, type I, gamma b isoform X1", "tax_id": 7955, "disease": "lethal congenital contracture syndrome 3 (Disease Ontology:DOID:0060653); cancer (Disease Ontology:DOID:162)", "pathway": " (dre:100005033)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "27189481;30321068;37451268", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0052742 phosphatidylinositol kinase activity;GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0046488 phosphatidylinositol metabolic process;GO:0046854 phosphatidylinositol phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0AC58G7V2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6R4-1", "uniprot_id": [ { "id": "A0ACD6B6R4_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6R4", "type": "external" } ], "mass": 45375.0, "length": 406, "protein_name": "Transcription factor E2F6 isoform X1", "gene_name": "e2f6", "organism": "Zebrafish", "refseq_name": "transcription factor E2F6", "refseq_ac": [ { "id": "NP_001025315", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025315", "type": "external" } ], "gene_names_uniprotkb": "e2f6; fb34f06; si:ch211-195d17.2; wu:fb34f06; zgc:136607", "gene_names_refseq": "e2f6; fb34f06; si:ch211-195d17.2; wu:fb34f06; zgc:136607", "protein_names_uniprotkb": "Transcription factor E2F6 isoform X1", "protein_names_refseq": "THAP-E2F6 fusion; transcription factor E2F6", "tax_id": 7955, "disease": "", "pathway": " (dre:560495)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15520368;15863623;18073205;21205313;26469318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01010361.1, SRR32588723.1370322.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505379 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On or before Jul 22, 2025 this sequence version replaced XP_005160782.2, NP_001025315.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0ACD6B6R4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7H4-1", "uniprot_id": [ { "id": "A0ACD6B7H4_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7H4", "type": "external" } ], "mass": 122195.0, "length": 1126, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "hipk1b", "organism": "Zebrafish", "refseq_name": "homeodomain-interacting protein kinase 1 isoform X1", "refseq_ac": [ { "id": "XP_009304049", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304049", "type": "external" } ], "gene_names_uniprotkb": "hipk1b", "gene_names_refseq": "hipk1b", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "homeodomain-interacting protein kinase 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:572323)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009304049.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004713 protein tyrosine kinase activity;GO:0016301 kinase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005634 nucleus;GO:0016605 PML body", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0007224 smoothened signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7H4-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7G6-1", "uniprot_id": [ { "id": "A0ACD6B7G6_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7G6", "type": "external" } ], "mass": 98865.0, "length": 880, "protein_name": "SH3 and PX domain-containing protein 2B isoform X1", "gene_name": "sh3pxd2b", "organism": "Zebrafish", "refseq_name": "SH3 and PX domain-containing protein 2B isoform X1", "refseq_ac": [ { "id": "XP_073791592", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073791592", "type": "external" } ], "gene_names_uniprotkb": "sh3pxd2b", "gene_names_refseq": "sh3pxd2b", "protein_names_uniprotkb": "SH3 and PX domain-containing protein 2B isoform X1", "protein_names_refseq": "SH3 and PX domain-containing protein 2B isoform X1", "tax_id": 7955, "disease": "Frank-Ter Haar syndrome (Disease Ontology:DOID:0111789); otitis media (Disease Ontology:DOID:10754); glaucoma (Disease Ontology:DOID:1686)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58IBI3", "ec_number_list": [], "go_molecular_function": "GO:0035091 phosphatidylinositol binding;GO:0016176 superoxide-generating NADPH oxidase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0002102 podosome", "go_biological_process": "GO:0060349 bone morphogenesis;GO:0061448 connective tissue development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7G6-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6X5-1", "uniprot_id": [ { "id": "A0ACD6B6X5_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6X5", "type": "external" } ], "mass": 84298.0, "length": 777, "protein_name": "Suppressor of cytokine signaling 7", "gene_name": "socs7", "organism": "Zebrafish", "refseq_name": "suppressor of cytokine signaling 7 isoform X1", "refseq_ac": [ { "id": "XP_009304138", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304138", "type": "external" } ], "gene_names_uniprotkb": "socs7; zgc:175115", "gene_names_refseq": "socs7; zgc:175115", "protein_names_uniprotkb": "Suppressor of cytokine signaling 7", "protein_names_refseq": "suppressor of cytokine signaling 7 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:556903)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "18029016;22412924;27189481;27614325;33440144;39139065", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009304138.1. COMPLETENESS: full length., [RefSeq]; Substrate-recognition component of a cullin-5-RING E3 ubiquitin-protein ligase complex (ECS complex, also named CRL5 complex), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as DAB1 and IRS1. Specifically recognizes and binds phosphorylated proteins via its SH2 domain, promoting their ubiquitination. The ECS(SOCS7) complex acts as a key regulator of reelin signaling by mediating ubiquitination and degradation of phosphorylated DAB1 in the cortical plate of the developing cerebral cortex, thereby regulating neuron positioning during cortex development. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Also inhibits prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0016567 protein ubiquitination;GO:0009968 negative regulation of signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0ACD6B6X5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7A6-1", "uniprot_id": [ { "id": "A0ACD6B7A6_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7A6", "type": "external" } ], "mass": 61989.0, "length": 550, "protein_name": "Src substrate protein p85-like isoform X1", "gene_name": "hcls1", "organism": "Zebrafish", "refseq_name": "src substrate protein p85-like isoform X1", "refseq_ac": [ { "id": "XP_005164938", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005164938", "type": "external" } ], "gene_names_uniprotkb": "hcls1; fk96b08; si:dkey-9a20.6; wu:fk96b08; zgc:154014", "gene_names_refseq": "fk96b08; hcls1; si:dkey-9a20.6; wu:fk96b08; zgc:154014", "protein_names_uniprotkb": "Src substrate protein p85-like isoform X1", "protein_names_refseq": "src substrate protein p85-like isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:563056)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "26469318;32327498;35531980;38739706", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005164938.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0ACD6B7A6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B686-1", "uniprot_id": [ { "id": "A0ACD6B686_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B686", "type": "external" } ], "mass": 118110.0, "length": 1059, "protein_name": "Histone-lysine N-methyltransferase EHMT1a isoform X1", "gene_name": "ehmt1a", "organism": "Zebrafish", "refseq_name": "histone-lysine N-methyltransferase EHMT1a isoform X1", "refseq_ac": [ { "id": "XP_005171835", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171835", "type": "external" } ], "gene_names_uniprotkb": "ehmt1a; bZ1O1.6; si:rp71-1o1.6; zgc:136244", "gene_names_refseq": "bZ1O1.6; ehmt1a; si:rp71-1o1.6; zgc:136244", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase EHMT1a isoform X1", "protein_names_refseq": "histone-lysine N-methyltransferase EHMT1a isoform X1", "tax_id": 7955, "disease": "Kleefstra syndrome 1 (Disease Ontology:DOID:0060352); Kleefstra syndrome (Disease Ontology:DOID:0080597); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748)", "pathway": " (dre:100005761)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "18231586;24240475;26469318;28738802", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005171835.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042054 histone methyltransferase activity;GO:0002039 p53 binding;GO:0016279 protein-lysine N-methyltransferase activity;GO:0140999 histone H3K4 trimethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0ACD6B686-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5W8-1", "uniprot_id": [ { "id": "A0ACD6B5W8_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5W8", "type": "external" } ], "mass": 68831.0, "length": 600, "protein_name": "Glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X1", "gene_name": "gdpd5a", "organism": "Zebrafish", "refseq_name": "glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X1", "refseq_ac": [ { "id": "XP_009303864", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303864", "type": "external" } ], "gene_names_uniprotkb": "gdpd5a", "gene_names_refseq": "gdpd5a", "protein_names_uniprotkb": "Glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X1", "protein_names_refseq": "glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009303864.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008081 phosphoric diester hydrolase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0045597 positive regulation of cell differentiation;GO:0036269 swimming behavior;GO:0035188 hatching", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5W8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G812-1", "uniprot_id": [ { "id": "A0AC58G812_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G812", "type": "external" } ], "mass": 110293.0, "length": 935, "protein_name": "Nexilin isoform X1", "gene_name": "nexn", "organism": "Zebrafish", "refseq_name": "nexilin isoform X1", "refseq_ac": [ { "id": "XP_073765877", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765877", "type": "external" } ], "gene_names_uniprotkb": "nexn; zgc:103442", "gene_names_refseq": "nexn; zgc:103442", "protein_names_uniprotkb": "Nexilin isoform X1", "protein_names_refseq": "nexilin isoform X1", "tax_id": 7955, "disease": "hypertrophic cardiomyopathy 20 (Disease Ontology:DOID:0110326); dilated cardiomyopathy 1CC (Disease Ontology:DOID:0110424)", "pathway": " (dre:573301)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "19308258;19325702;19881492;21468032;21730303;29735270;29777134;30837568;32762296;38114601", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58G827", "ec_number_list": [], "go_molecular_function": "GO:0098632 cell-cell adhesion mediator activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0030424 axon;GO:0030018 Z disc", "go_biological_process": "GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0055013 cardiac muscle cell development;GO:0007411 axon guidance;GO:0070593 dendrite self-avoidance", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "A0AC58G812-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6Q7-1", "uniprot_id": [ { "id": "A0ACD6B6Q7_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6Q7", "type": "external" } ], "mass": 15592.0, "length": 146, "protein_name": "Acyl-coenzyme A thioesterase 13", "gene_name": "acot13", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "acot13; si:dkey-218n20.4; them2", "gene_names_refseq": "", "protein_names_uniprotkb": "Acyl-coenzyme A thioesterase 13; Hotdog-fold thioesterase superfamily member 2; Palmitoyl-CoA hydrolase; Thioesterase superfamily member 2", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:564010)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "23192039;26067557;27189481;28252024;39228401;40044042", "class_list": "", "function": "Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Can also hydrolyze 3-hydroxyphenylacetyl-CoA and 3,4-dihydroxyphenylacetyl-CoA (in vitro). May play a role in controlling adaptive thermogenesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.2.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22", "type": "external" } ], "go_molecular_function": "GO:0052816 long-chain fatty acyl-CoA hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005819 spindle;GO:0005829 cytosol", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0ACD6B6Q7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5E1-1", "uniprot_id": [ { "id": "A0ACD6B5E1_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5E1", "type": "external" } ], "mass": 141360.0, "length": 1252, "protein_name": "IQ motif and SEC7 domain-containing protein 1 isoform X1", "gene_name": "iqsec1b", "organism": "Zebrafish", "refseq_name": "IQ motif and SEC7 domain-containing protein 1 isoform X1", "refseq_ac": [ { "id": "XP_005169390", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169390", "type": "external" } ], "gene_names_uniprotkb": "iqsec1b", "gene_names_refseq": "iqsec1b", "protein_names_uniprotkb": "IQ motif and SEC7 domain-containing protein 1 isoform X1", "protein_names_refseq": "IQ motif and SEC7 domain-containing protein 1 isoform X1", "tax_id": 7955, "disease": "intellectual developmental disorder with short stature and behavioral abnormalities (Disease Ontology:DOID:0111674); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005169390.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0001525 angiogenesis;GO:0001946 lymphangiogenesis;GO:0001944 vasculature development;GO:0032012 regulation of ARF protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5E1-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5T7-1", "uniprot_id": [ { "id": "A0ACD6B5T7_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5T7", "type": "external" } ], "mass": 128169.0, "length": 1117, "protein_name": "Osteoclast-stimulating factor 1", "gene_name": "myo1ea", "organism": "Zebrafish", "refseq_name": "unconventional myosin-Ie isoform X1", "refseq_ac": [ { "id": "XP_005168983", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168983", "type": "external" } ], "gene_names_uniprotkb": "myo1ea", "gene_names_refseq": "myo1ea", "protein_names_uniprotkb": "Osteoclast-stimulating factor 1", "protein_names_refseq": "unconventional myosin-Ie isoform X1", "tax_id": 7955, "disease": "focal segmental glomerulosclerosis 6 (Disease Ontology:DOID:0111131)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005168983.1. COMPLETENESS: full length., [RefSeq]; Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0003774 cytoskeletal motor activity", "go_cellular_component": "GO:0016459 myosin complex", "go_biological_process": "GO:0032835 glomerulus development;GO:0003094 glomerular filtration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5T7-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6T2-1", "uniprot_id": [ { "id": "A0ACD6B6T2_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6T2", "type": "external" } ], "mass": 24955.0, "length": 225, "protein_name": "Pentraxin family member", "gene_name": "crp7", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "crp7; CRP; si:ch211-234p6.7; zgc:171660", "gene_names_refseq": "", "protein_names_uniprotkb": "Pentraxin family member", "protein_names_refseq": "", "tax_id": 7955, "disease": "mevalonic aciduria (Disease Ontology:DOID:0050452); inflammatory bowel disease (Disease Ontology:DOID:0050589); obstructive sleep apnea (Disease Ontology:DOID:0050848); renal fibrosis (Disease Ontology:DOID:0050855); non-arteritic anterior ischemic optic neuropathy (Disease Ontology:DOID:0050864); atrial fibrillation (Disease Ontology:DOID:0060224); mastoiditis (Disease Ontology:DOID:0060322); overactive bladder syndrome (Disease Ontology:DOID:0070355); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); lupus nephritis (Disease Ontology:DOID:0080162); COVID-19 (Disease Ontology:DOID:0080600); pelvic inflammatory disease (Disease Ontology:DOID:1003); bacterial infectious disease (Disease Ontology:DOID:104); interstitial nephritis (Disease Ontology:DOID:1063); renal hypertension (Disease Ontology:DOID:1073); kidney failure (Disease Ontology:DOID:1074); otitis media (Disease Ontology:DOID:10754); hypertension (Disease Ontology:DOID:10763); Kuhnt-Junius degeneration (Disease Ontology:DOID:10873); heart disease (Disease Ontology:DOID:114); pyelonephritis (Disease Ontology:DOID:11400); hypertensive retinopathy (Disease Ontology:DOID:11561); familial hyperlipidemia (Disease Ontology:DOID:1168); iron deficiency anemia (Disease Ontology:DOID:11758); vestibular neuronitis (Disease Ontology:DOID:12683); cardiovascular system disease (Disease Ontology:DOID:1287); Sjogren's syndrome (Disease Ontology:DOID:12894); Behcet's disease (Disease Ontology:DOID:13241); Mycoplasma pneumoniae pneumonia (Disease Ontology:DOID:13276); temporal arteritis (Disease Ontology:DOID:13375); Kawasaki disease (Disease Ontology:DOID:13378); pulmonary sarcoidosis (Disease Ontology:DOID:13406); low tension glaucoma (Disease Ontology:DOID:13544); aspergillosis (Disease Ontology:DOID:13564); pharyngoconjunctival fever (Disease Ontology:DOID:13801); interstitial cystitis (Disease Ontology:DOID:13949); alcoholic liver cirrhosis (Disease Ontology:DOID:14018); Parkinson's disease (Disease Ontology:DOID:14330); aggressive periodontitis (Disease Ontology:DOID:1474); urticaria (Disease Ontology:DOID:1555); depressive disorder (Disease Ontology:DOID:1596); breast cancer (Disease Ontology:DOID:1612); retinal vein occlusion (Disease Ontology:DOID:1727); status epilepticus (Disease Ontology:DOID:1824); atherosclerosis (Disease Ontology:DOID:1936); anxiety disorder (Disease Ontology:DOID:2030); colon cancer (Disease Ontology:DOID:219); opiate dependence (Disease Ontology:DOID:2559); asthma (Disease Ontology:DOID:2841); bronchiolitis (Disease Ontology:DOID:2942); pulmonary tuberculosis (Disease Ontology:DOID:2957); antiphospholipid syndrome (Disease Ontology:DOID:2988); acute kidney failure (Disease Ontology:DOID:3021); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); coronary artery disease (Disease Ontology:DOID:3393); breast carcinoma (Disease Ontology:DOID:3459); middle cerebral artery infarction (Disease Ontology:DOID:3525); mouth disease (Disease Ontology:DOID:403); macular degeneration (Disease Ontology:DOID:4448); renal cell carcinoma (Disease Ontology:DOID:4450); liver cirrhosis (Disease Ontology:DOID:5082); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); pneumonia (Disease Ontology:DOID:552); myocardial infarction (Disease Ontology:DOID:5844); uveal melanoma (Disease Ontology:DOID:6039); acute stress disorder (Disease Ontology:DOID:6088); lymphopenia (Disease Ontology:DOID:614); pulmonary hypertension (Disease Ontology:DOID:6432); systemic juvenile rheumatoid arthritis (Disease Ontology:DOID:676); ankylosing spondylitis (Disease Ontology:DOID:7147); rheumatoid arthritis (Disease Ontology:DOID:7148); abdominal aortic aneurysm (Disease Ontology:DOID:7693); end stage renal disease (Disease Ontology:DOID:783); arthritis (Disease Ontology:DOID:848); polymyalgia rheumatica (Disease Ontology:DOID:853); Crohn's disease (Disease Ontology:DOID:8778); intermediate coronary syndrome (Disease Ontology:DOID:8805); psoriasis (Disease Ontology:DOID:8893); diabetic retinopathy (Disease Ontology:DOID:8947); systemic lupus erythematosus (Disease Ontology:DOID:9074); amyloidosis (Disease Ontology:DOID:9120); type 2 diabetes mellitus (Disease Ontology:DOID:9352); otitis externa (Disease Ontology:DOID:9463); bacterial meningitis (Disease Ontology:DOID:9470); type 1 diabetes mellitus (Disease Ontology:DOID:9744); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:100124600)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "22079493;22805612;24683187;25592778;26270536;27189481;28915434;30170110;30653529", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 86, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008142 oxysterol binding;GO:0046872 metal ion binding;GO:0015485 cholesterol binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0051607 defense response to virus", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0ACD6B6T2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6M8-1", "uniprot_id": [ { "id": "A0ACD6B6M8_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6M8", "type": "external" } ], "mass": 153656.0, "length": 1365, "protein_name": "Phospholipid-transporting ATPase", "gene_name": "atp10d", "organism": "Zebrafish", "refseq_name": "phospholipid-transporting ATPase VD isoform X1", "refseq_ac": [ { "id": "XP_005156631", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005156631", "type": "external" } ], "gene_names_uniprotkb": "atp10d; si:dkey-20i10.6", "gene_names_refseq": "atp10d; si:dkey-20i10.6", "protein_names_uniprotkb": "Phospholipid-transporting ATPase; 7.6.2.1", "protein_names_refseq": "phospholipid-transporting ATPase VD isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:571658)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "24683187;26469318", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005156631.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140351 glycosylceramide flippase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:1990531 phospholipid-translocating ATPase complex", "go_biological_process": "GO:0015914 phospholipid transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0ACD6B6M8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5C4-1", "uniprot_id": [ { "id": "A0ACD6B5C4_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5C4", "type": "external" } ], "mass": 58040.0, "length": 539, "protein_name": "Amino acid transporter", "gene_name": "slc1a4", "organism": "Zebrafish", "refseq_name": "neutral amino acid transporter A isoform X1", "refseq_ac": [ { "id": "XP_005156843", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005156843", "type": "external" } ], "gene_names_uniprotkb": "slc1a4; si:zc101n13.5; zgc:92817", "gene_names_refseq": "si:zc101n13.5; slc1a4; zgc:92817", "protein_names_uniprotkb": "Amino acid transporter", "protein_names_refseq": "neutral amino acid transporter A isoform X1", "tax_id": 7955, "disease": "episodic ataxia type 6 (Disease Ontology:DOID:0050994); spastic tetraplegia, thin corpus callosum, and progressive microcephaly (Disease Ontology:DOID:0070537); neurodegenerative disease (Disease Ontology:DOID:1289); epilepsy (Disease Ontology:DOID:1826)", "pathway": " (dre:368885)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "20429920;20466040;26469318;28252024;28694436;28888969;33800130;35134499;39456733", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005156843.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015293 symporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0048679 regulation of axon regeneration;GO:1902475 L-alpha-amino acid transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0ACD6B5C4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B748-1", "uniprot_id": [ { "id": "A0ACD6B748_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B748", "type": "external" } ], "mass": 535186.0, "length": 4929, "protein_name": "Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6", "gene_name": "birc6", "organism": "Zebrafish", "refseq_name": "dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 isoform X1", "refseq_ac": [ { "id": "XP_009291311", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009291311", "type": "external" } ], "gene_names_uniprotkb": "birc6", "gene_names_refseq": "birc6", "protein_names_uniprotkb": "Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6; 2.3.2.24; BIR repeat-containing ubiquitin-conjugating enzyme; Baculoviral IAP repeat-containing protein 6; Ubiquitin-conjugating BIR domain enzyme apollon", "protein_names_refseq": "dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009291311.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004869 cysteine-type endopeptidase inhibitor activity;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005768 endosome;GO:0005794 Golgi apparatus;GO:0005813 centrosome;GO:0030496 midbody", "go_biological_process": "GO:0042127 regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0051301 cell division;GO:0006915 apoptotic process;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B748-1", "record_type": "protein", "filter_code": "0000000.0000000.000100.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G7W5-1", "uniprot_id": [ { "id": "A0AC58G7W5_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G7W5", "type": "external" } ], "mass": 96509.0, "length": 895, "protein_name": "Espin isoform X1", "gene_name": "espn", "organism": "Zebrafish", "refseq_name": "espin isoform X1", "refseq_ac": [ { "id": "XP_073765811", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765811", "type": "external" } ], "gene_names_uniprotkb": "espn; si:dkey-77h17.1", "gene_names_refseq": "espn; si:dkey-77h17.1", "protein_names_uniprotkb": "Espin isoform X1", "protein_names_refseq": "espin isoform X1", "tax_id": 7955, "disease": "autosomal recessive nonsyndromic deafness 36 (Disease Ontology:DOID:0110494)", "pathway": " (dre:567061)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "26048245;26469318;27806254;31002663;34325655;36791723", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding", "go_cellular_component": "GO:0032420 stereocilium", "go_biological_process": "GO:0007605 sensory perception of sound;GO:0048858 cell projection morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0AC58G7W5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B602-1", "uniprot_id": [ { "id": "A0ACD6B602_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B602", "type": "external" } ], "mass": 160394.0, "length": 1440, "protein_name": "Gem-associated protein 5 isoform X1", "gene_name": "gemin5", "organism": "Zebrafish", "refseq_name": "gem-associated protein 5 isoform X1", "refseq_ac": [ { "id": "XP_001339880", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001339880", "type": "external" } ], "gene_names_uniprotkb": "gemin5", "gene_names_refseq": "gemin5", "protein_names_uniprotkb": "Gem-associated protein 5 isoform X1", "protein_names_refseq": "gem-associated protein 5 isoform X1", "tax_id": 7955, "disease": "cerebellar ataxia (Disease Ontology:DOID:0050753); neurodevelopmental disorder with cerebellar atrophy and motor dysfunction (Disease Ontology:DOID:0070443)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001339880.4. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0042246 tissue regeneration;GO:0030217 T cell differentiation;GO:0070657 neuromast regeneration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B602-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5T3-1", "uniprot_id": [ { "id": "A0ACD6B5T3_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5T3", "type": "external" } ], "mass": 120738.0, "length": 1079, "protein_name": "Retinoblastoma-like protein 2", "gene_name": "rbl2", "organism": "Zebrafish", "refseq_name": "retinoblastoma-like protein 2 isoform X1", "refseq_ac": [ { "id": "XP_002667000", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002667000", "type": "external" } ], "gene_names_uniprotkb": "rbl2", "gene_names_refseq": "rbl2", "protein_names_uniprotkb": "Retinoblastoma-like protein 2; 130 kDa retinoblastoma-associated protein; Retinoblastoma-related protein 2; pRb2", "protein_names_refseq": "retinoblastoma-like protein 2 isoform X1", "tax_id": 7955, "disease": "Brunet-Wagner neurodevelopmental syndrome (Disease Ontology:DOID:0061126)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_002667000.3. COMPLETENESS: full length., [RefSeq]; Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006325 chromatin organization;GO:0051726 regulation of cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5T3-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6S1-1", "uniprot_id": [ { "id": "A0ACD6B6S1_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6S1", "type": "external" } ], "mass": 63617.0, "length": 567, "protein_name": "Centrosomal protein POC5", "gene_name": "poc5", "organism": "Zebrafish", "refseq_name": "centrosomal protein POC5 isoform X1", "refseq_ac": [ { "id": "XP_691080", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691080", "type": "external" } ], "gene_names_uniprotkb": "poc5", "gene_names_refseq": "poc5", "protein_names_uniprotkb": "Centrosomal protein POC5; Protein of centriole 5", "protein_names_refseq": "centrosomal protein POC5 isoform X1", "tax_id": 7955, "disease": "retinitis pigmentosa (Disease Ontology:DOID:10584)", "pathway": " (dre:562608)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_691080.3. COMPLETENESS: full length., [RefSeq]; Essential for the assembly of the distal half of centrioles, required for centriole elongation. Acts as a negative regulator of centriole elongation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005814 centriole;GO:0032391 photoreceptor connecting cilium", "go_biological_process": "GO:0042462 eye photoreceptor cell development;GO:0007632 visual behavior", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6S1-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5Y8-1", "uniprot_id": [ { "id": "A0ACD6B5Y8_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5Y8", "type": "external" } ], "mass": 311428.0, "length": 2759, "protein_name": "Neurofibromin", "gene_name": "nf1b", "organism": "Zebrafish", "refseq_name": "neurofibromin isoform X1", "refseq_ac": [ { "id": "XP_005169246", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169246", "type": "external" } ], "gene_names_uniprotkb": "nf1b", "gene_names_refseq": "nf1b", "protein_names_uniprotkb": "Neurofibromin; Neurofibromatosis-related protein NF-1", "protein_names_refseq": "neurofibromin isoform X1", "tax_id": 7955, "disease": "juvenile myelomonocytic leukemia (Disease Ontology:DOID:0050458); spinal neurofibromatosis (Disease Ontology:DOID:0070482); Watson syndrome (Disease Ontology:DOID:0070483); colorectal carcinoma (Disease Ontology:DOID:0080199); neurofibromatosis 1 (Disease Ontology:DOID:0111253); neurofibromatosis-Noonan syndrome (Disease Ontology:DOID:0111683); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); autistic disorder (Disease Ontology:DOID:12849); colon cancer (Disease Ontology:DOID:219); malignant astrocytoma (Disease Ontology:DOID:3069); high grade glioma (Disease Ontology:DOID:3070); lung non-small cell carcinoma (Disease Ontology:DOID:3908); optic nerve glioma (Disease Ontology:DOID:4992); plexiform neurofibroma (Disease Ontology:DOID:5151); sleep disorder (Disease Ontology:DOID:535); neurofibromatosis (Disease Ontology:DOID:8712); acute myeloid leukemia (Disease Ontology:DOID:9119)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005169246.1. COMPLETENESS: full length., [RefSeq]; Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 17, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008289 lipid binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0046959 habituation;GO:0007507 heart development;GO:0007613 memory;GO:0001568 blood vessel development;GO:0070373 negative regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5Y8-1", "record_type": "protein", "filter_code": "0000000.0000010.001000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5T4-1", "uniprot_id": [ { "id": "A0ACD6B5T4_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5T4", "type": "external" } ], "mass": 73403.0, "length": 670, "protein_name": "Caprin-1a isoform X1", "gene_name": "caprin1a", "organism": "Zebrafish", "refseq_name": "caprin-1a isoform X1", "refseq_ac": [ { "id": "XP_005172331", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005172331", "type": "external" } ], "gene_names_uniprotkb": "caprin1a; caprin; gpiap1; m11s1; wu:fb49b05; wu:fc35g01; zgc:92043", "gene_names_refseq": "caprin1a; caprin; gpiap1; m11s1; wu:fb49b05; wu:fc35g01; zgc:92043", "protein_names_uniprotkb": "Caprin-1a isoform X1", "protein_names_refseq": "caprin-1a isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005172331.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0042802 identical protein binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0030154 cell differentiation;GO:0017148 negative regulation of translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5T4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7B9-1", "uniprot_id": [ { "id": "A0ACD6B7B9_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7B9", "type": "external" } ], "mass": 108672.0, "length": 993, "protein_name": "Trafficking kinesin-binding protein 2 isoform X1", "gene_name": "trak2", "organism": "Zebrafish", "refseq_name": "trafficking kinesin-binding protein 2 isoform X1", "refseq_ac": [ { "id": "XP_689302", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689302", "type": "external" } ], "gene_names_uniprotkb": "trak2", "gene_names_refseq": "trak2", "protein_names_uniprotkb": "Trafficking kinesin-binding protein 2 isoform X1", "protein_names_refseq": "trafficking kinesin-binding protein 2 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_689302.5. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7B9-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5E4-1", "uniprot_id": [ { "id": "A0ACD6B5E4_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5E4", "type": "external" } ], "mass": 80427.0, "length": 729, "protein_name": "ATP-dependent zinc metalloprotease YME1L1", "gene_name": "yme1l1a", "organism": "Zebrafish", "refseq_name": "ATP-dependent zinc metalloprotease YME1L1 isoform X1", "refseq_ac": [ { "id": "XP_005162918", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005162918", "type": "external" } ], "gene_names_uniprotkb": "yme1l1a", "gene_names_refseq": "yme1l1a", "protein_names_uniprotkb": "ATP-dependent zinc metalloprotease YME1L1; ATP-dependent metalloprotease FtsH1; YME1-like protein 1", "protein_names_refseq": "ATP-dependent zinc metalloprotease YME1L1 isoform X1", "tax_id": 7955, "disease": "optic atrophy 11 (Disease Ontology:DOID:0111436)", "pathway": " (dre:793098)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005162918.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0004176 ATP-dependent peptidase activity", "go_cellular_component": "GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0010636 positive regulation of mitochondrial fusion;GO:0034982 mitochondrial protein processing;GO:0009653 anatomical structure morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5E4-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G6J7-1", "uniprot_id": [ { "id": "A0AC58G6J7_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G6J7", "type": "external" } ], "mass": 28417.0, "length": 259, "protein_name": "NFU1 iron-sulfur cluster scaffold homolog, mitochondrial", "gene_name": "nfu1", "organism": "Zebrafish", "refseq_name": "NFU1 iron-sulfur cluster scaffold homolog, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_073765366", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765366", "type": "external" } ], "gene_names_uniprotkb": "nfu1; hirip5; zgc:109711", "gene_names_refseq": "hirip5; nfu1; zgc:109711", "protein_names_uniprotkb": "NFU1 iron-sulfur cluster scaffold homolog, mitochondrial; HIRA-interacting protein 5", "protein_names_refseq": "NFU1 iron-sulfur cluster scaffold homolog, mitochondrial isoform X1", "tax_id": 7955, "disease": "hereditary spastic paraplegia 93 (Disease Ontology:DOID:0070645); multiple mitochondrial dysfunctions syndrome 1 (Disease Ontology:DOID:0080133)", "pathway": " (dre:403053); (R-DRE-9857492)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "15520368;16466575;17013923;26469318;27189481;28252024;28582574", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Iron-sulfur cluster scaffold protein which can assemble [4Fe-4S] clusters and deliver them to target proteins., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005506 iron ion binding;GO:0051539 4 iron, 4 sulfur cluster binding", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0051604 protein maturation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0AC58G6J7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G7J8-1", "uniprot_id": [ { "id": "A0AC58G7J8_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G7J8", "type": "external" } ], "mass": 48398.0, "length": 419, "protein_name": "Hexosyltransferase", "gene_name": "b3gnt3.3", "organism": "Zebrafish", "refseq_name": "N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3.3 isoform X1", "refseq_ac": [ { "id": "XP_073765703", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765703", "type": "external" } ], "gene_names_uniprotkb": "b3gnt3.3; si:ch211-126g16.11", "gene_names_refseq": "b3gnt3.3; si:ch211-126g16.11", "protein_names_uniprotkb": "Hexosyltransferase; 2.4.1.-", "protein_names_refseq": "N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3.3 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:561028); (R-DRE-913709)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "26469318;31415728", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" }, { "id": "2.4.1.206", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.206", "type": "external" } ], "go_molecular_function": "GO:0008194 UDP-glycosyltransferase activity;GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0016266 protein O-linked glycosylation via N-acetyl-galactosamine;GO:0030311 poly-N-acetyllactosamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0AC58G7J8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5Q0-1", "uniprot_id": [ { "id": "A0ACD6B5Q0_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5Q0", "type": "external" } ], "mass": 94361.0, "length": 832, "protein_name": "Vacuolar protein sorting-associated protein 53 homolog", "gene_name": "vps53", "organism": "Zebrafish", "refseq_name": "vacuolar protein sorting-associated protein 53 homolog isoform X1", "refseq_ac": [ { "id": "XP_005157637", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157637", "type": "external" } ], "gene_names_uniprotkb": "vps53; wu:fb77d11; zgc:103741", "gene_names_refseq": "vps53; wu:fb77d11; zgc:103741", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 53 homolog", "protein_names_refseq": "vacuolar protein sorting-associated protein 53 homolog isoform X1", "tax_id": 7955, "disease": "pontocerebellar hypoplasia type 2E (Disease Ontology:DOID:0060271)", "pathway": " (dre:492817)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "27189481;28252024", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005157637.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000938 GARP complex;GO:0005829 cytosol;GO:0055037 recycling endosome;GO:0010008 endosome membrane", "go_biological_process": "GO:0015031 protein transport;GO:0042147 retrograde transport, endosome to Golgi;GO:0007041 lysosomal transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0ACD6B5Q0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G7Z5-1", "uniprot_id": [ { "id": "A0AC58G7Z5_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G7Z5", "type": "external" } ], "mass": 70043.0, "length": 620, "protein_name": "Uncharacterized protein KIAA2013 homolog isoform X1", "gene_name": "si:dkeyp-104h9.5", "organism": "Zebrafish", "refseq_name": "uncharacterized protein KIAA2013 homolog isoform X1", "refseq_ac": [ { "id": "XP_073765841", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765841", "type": "external" } ], "gene_names_uniprotkb": "si:dkeyp-104h9.5", "gene_names_refseq": "si:dkeyp-104h9.5", "protein_names_uniprotkb": "Uncharacterized protein KIAA2013 homolog isoform X1", "protein_names_refseq": "uncharacterized protein KIAA2013 homolog isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:568307)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "26469318;27189481", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0AC58G7Z5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6X7-1", "uniprot_id": [ { "id": "A0ACD6B6X7_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6X7", "type": "external" } ], "mass": 51909.0, "length": 459, "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "pparab", "organism": "Zebrafish", "refseq_name": "peroxisome proliferator-activated receptor alpha b isoform X1", "refseq_ac": [ { "id": "XP_009295973", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009295973", "type": "external" } ], "gene_names_uniprotkb": "pparab; PPAR[a]; ppara1; pparal; ppara", "gene_names_refseq": "PPAR[a]; ppara1; pparab; pparal; ppara", "protein_names_uniprotkb": "Peroxisome proliferator-activated receptor alpha; Nuclear receptor subfamily 1 group C member 1", "protein_names_refseq": "peroxisome proliferator-activated receptor alpha b isoform X1", "tax_id": 7955, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); hydrocephalus (Disease Ontology:DOID:10908); morbid obesity (Disease Ontology:DOID:11981); alcoholic hepatitis (Disease Ontology:DOID:12351); cystic fibrosis (Disease Ontology:DOID:1485); alcohol use disorder (Disease Ontology:DOID:1574); lipid metabolism disorder (Disease Ontology:DOID:3146); coronary artery disease (Disease Ontology:DOID:3393); schizophrenia (Disease Ontology:DOID:5419); myocardial infarction (Disease Ontology:DOID:5844); hepatocellular carcinoma (Disease Ontology:DOID:684); periodontitis (Disease Ontology:DOID:824); diabetes mellitus (Disease Ontology:DOID:9351); hypertensive encephalopathy (Disease Ontology:DOID:9427); steatotic liver disease (Disease Ontology:DOID:9452); obesity (Disease Ontology:DOID:9970)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009295973.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 17, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008289 lipid binding;GO:0043565 sequence-specific DNA binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0070417 cellular response to cold;GO:0006351 DNA-templated transcription;GO:0014823 response to activity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6X7-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6V2-1", "uniprot_id": [ { "id": "A0ACD6B6V2_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6V2", "type": "external" } ], "mass": 107156.0, "length": 951, "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "cyld", "organism": "Zebrafish", "refseq_name": "ubiquitin carboxyl-terminal hydrolase CYLD isoform X1", "refseq_ac": [ { "id": "XP_684817", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_684817", "type": "external" } ], "gene_names_uniprotkb": "cyld", "gene_names_refseq": "cyld", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase CYLD; 3.4.19.12; Deubiquitinating enzyme CYLD; Ubiquitin thioesterase CYLD; Ubiquitin-specific-processing protease CYLD", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase CYLD isoform X1", "tax_id": 7955, "disease": "Brooke-Spiegler syndrome (Disease Ontology:DOID:0050693); multiple familial trichoepithelioma 1 (Disease Ontology:DOID:0061187)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_684817.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004843 cysteine-type deubiquitinase activity;GO:0061578 K63-linked deubiquitinase activity;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005813 centrosome;GO:0005819 spindle;GO:0005874 microtubule;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:1904888 cranial skeletal system development;GO:0021551 central nervous system morphogenesis;GO:0006508 proteolysis;GO:0045087 innate immune response;GO:0016055 Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6V2-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B739-1", "uniprot_id": [ { "id": "A0ACD6B739_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B739", "type": "external" } ], "mass": 112019.0, "length": 1034, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "ulk2", "organism": "Zebrafish", "refseq_name": "serine/threonine-protein kinase ULK2 isoform X1", "refseq_ac": [ { "id": "XP_002664661", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664661", "type": "external" } ], "gene_names_uniprotkb": "ulk2", "gene_names_refseq": "ulk2", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase ULK2 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_002664661.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016301 kinase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B739-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B734-1", "uniprot_id": [ { "id": "A0ACD6B734_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B734", "type": "external" } ], "mass": 63919.0, "length": 580, "protein_name": "Na(+)/citrate cotransporter isoform X1", "gene_name": "slc13a5b", "organism": "Zebrafish", "refseq_name": "Na(+)/citrate cotransporter isoform X1", "refseq_ac": [ { "id": "XP_001345110", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001345110", "type": "external" } ], "gene_names_uniprotkb": "slc13a5b", "gene_names_refseq": "slc13a5b", "protein_names_uniprotkb": "Na(+)/citrate cotransporter isoform X1", "protein_names_refseq": "Na(+)/citrate cotransporter isoform X1", "tax_id": 7955, "disease": "developmental and epileptic encephalopathy 25 (Disease Ontology:DOID:0080453)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001345110.4. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B734-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5W4-1", "uniprot_id": [ { "id": "A0ACD6B5W4_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5W4", "type": "external" } ], "mass": 137232.0, "length": 1224, "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 16 isoform X1", "gene_name": "adamts16", "organism": "Zebrafish", "refseq_name": "A disintegrin and metalloproteinase with thrombospondin motifs 16 isoform X1", "refseq_ac": [ { "id": "XP_001922446", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922446", "type": "external" } ], "gene_names_uniprotkb": "adamts16", "gene_names_refseq": "adamts16", "protein_names_uniprotkb": "A disintegrin and metalloproteinase with thrombospondin motifs 16 isoform X1", "protein_names_refseq": "A disintegrin and metalloproteinase with thrombospondin motifs 16 isoform X1", "tax_id": 7955, "disease": "coloboma (Disease Ontology:DOID:12270)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001922446.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008237 metallopeptidase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5W4-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B685-1", "uniprot_id": [ { "id": "A0ACD6B685_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B685", "type": "external" } ], "mass": 304228.0, "length": 2737, "protein_name": "[histone H3]-lysine(36) N-trimethyltransferase", "gene_name": "setd2", "organism": "Zebrafish", "refseq_name": "histone-lysine N-methyltransferase SETD2 isoform X1", "refseq_ac": [ { "id": "XP_009290459", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290459", "type": "external" } ], "gene_names_uniprotkb": "setd2", "gene_names_refseq": "setd2", "protein_names_uniprotkb": "[histone H3]-lysine(36) N-trimethyltransferase; 2.1.1.359", "protein_names_refseq": "histone-lysine N-methyltransferase SETD2 isoform X1", "tax_id": 7955, "disease": "idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); autosomal dominant intellectual developmental disorder 70 (Disease Ontology:DOID:0061043); stomach cancer (Disease Ontology:DOID:10534); malignant mesothelioma (Disease Ontology:DOID:1790); liver cancer (Disease Ontology:DOID:3571); lung adenocarcinoma (Disease Ontology:DOID:3910); clear cell renal cell carcinoma (Disease Ontology:DOID:4467); malignant pleural mesothelioma (Disease Ontology:DOID:7474); gastrointestinal stromal tumor (Disease Ontology:DOID:9253); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009290459.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B685-1", "record_type": "protein", "filter_code": "0000000.0000010.001000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5E8-1", "uniprot_id": [ { "id": "A0ACD6B5E8_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5E8", "type": "external" } ], "mass": 94774.0, "length": 865, "protein_name": "Nuclear factor of activated T-cells, cytoplasmic 4 isoform X1", "gene_name": "nfatc4", "organism": "Zebrafish", "refseq_name": "nuclear factor of activated T-cells, cytoplasmic 4 isoform X1", "refseq_ac": [ { "id": "XP_690183", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690183", "type": "external" } ], "gene_names_uniprotkb": "nfatc4", "gene_names_refseq": "nfatc4", "protein_names_uniprotkb": "Nuclear factor of activated T-cells, cytoplasmic 4 isoform X1", "protein_names_refseq": "nuclear factor of activated T-cells, cytoplasmic 4 isoform X1", "tax_id": 7955, "disease": "dilated cardiomyopathy (Disease Ontology:DOID:12930)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_690183.5. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5E8-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6E0-1", "uniprot_id": [ { "id": "A0ACD6B6E0_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6E0", "type": "external" } ], "mass": 93313.0, "length": 818, "protein_name": "Toll-like receptor 2", "gene_name": "tlr2", "organism": "Zebrafish", "refseq_name": "toll-like receptor 2 isoform X1", "refseq_ac": [ { "id": "XP_005170910", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170910", "type": "external" } ], "gene_names_uniprotkb": "tlr2", "gene_names_refseq": "tlr2", "protein_names_uniprotkb": "Toll-like receptor 2", "protein_names_refseq": "toll-like receptor 2 isoform X1", "tax_id": 7955, "disease": "sinusitis (Disease Ontology:DOID:0050127); alcohol dependence (Disease Ontology:DOID:0050741); atrial fibrillation (Disease Ontology:DOID:0060224); mastoiditis (Disease Ontology:DOID:0060322); meningococcal meningitis (Disease Ontology:DOID:0080176); urinary tract infection (Disease Ontology:DOID:0080784); dry eye syndrome (Disease Ontology:DOID:10140); dermatomyositis (Disease Ontology:DOID:10223); leprosy (Disease Ontology:DOID:1024); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); otitis media (Disease Ontology:DOID:10754); Kuhnt-Junius degeneration (Disease Ontology:DOID:10873); cholesteatoma of middle ear (Disease Ontology:DOID:10964); urinary bladder cancer (Disease Ontology:DOID:11054); anogenital venereal wart (Disease Ontology:DOID:11168); suppurative otitis media (Disease Ontology:DOID:11506); alveolar echinococcosis (Disease Ontology:DOID:12148); vitiligo (Disease Ontology:DOID:12306); Behcet's disease (Disease Ontology:DOID:13241); pulmonary sarcoidosis (Disease Ontology:DOID:13406); familial combined hyperlipidemia (Disease Ontology:DOID:13809); alcoholic liver cirrhosis (Disease Ontology:DOID:14018); anterior uveitis (Disease Ontology:DOID:1407); cystic echinococcosis (Disease Ontology:DOID:1495); alcohol use disorder (Disease Ontology:DOID:1574); diffuse scleroderma (Disease Ontology:DOID:1580); breast cancer (Disease Ontology:DOID:1612); asthma (Disease Ontology:DOID:2841); severe acute respiratory syndrome (Disease Ontology:DOID:2945); pulmonary tuberculosis (Disease Ontology:DOID:2957); skin papilloma (Disease Ontology:DOID:3178); atopic dermatitis (Disease Ontology:DOID:3310); tuberculosis (Disease Ontology:DOID:399); allergic rhinitis (Disease Ontology:DOID:4481); rhinitis (Disease Ontology:DOID:4483); keratitis (Disease Ontology:DOID:4677); eye disease (Disease Ontology:DOID:5614); acne (Disease Ontology:DOID:6543); hepatocellular carcinoma (Disease Ontology:DOID:684); end stage renal disease (Disease Ontology:DOID:783); peritonitis (Disease Ontology:DOID:8283); lung disease (Disease Ontology:DOID:850); gastroesophageal reflux disease (Disease Ontology:DOID:8534); cholesteatoma (Disease Ontology:DOID:869); seborrheic dermatitis (Disease Ontology:DOID:8741); molluscum contagiosum (Disease Ontology:DOID:8867); psoriasis (Disease Ontology:DOID:8893); cutaneous leishmaniasis (Disease Ontology:DOID:9111); colorectal cancer (Disease Ontology:DOID:9256); keratoconjunctivitis (Disease Ontology:DOID:9368); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005170910.1. COMPLETENESS: full length., [RefSeq]; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 52, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6E0-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6P8-1", "uniprot_id": [ { "id": "A0ACD6B6P8_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6P8", "type": "external" } ], "mass": 237090.0, "length": 2069, "protein_name": "Unconventional myosin-X isoform X1", "gene_name": "myo10", "organism": "Zebrafish", "refseq_name": "unconventional myosin-X isoform X1", "refseq_ac": [ { "id": "XP_005171458", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171458", "type": "external" } ], "gene_names_uniprotkb": "myo10", "gene_names_refseq": "myo10", "protein_names_uniprotkb": "Unconventional myosin-X isoform X1", "protein_names_refseq": "unconventional myosin-X isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005171458.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6P8-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B693-1", "uniprot_id": [ { "id": "A0ACD6B693_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B693", "type": "external" } ], "mass": 116412.0, "length": 1071, "protein_name": "Peroxisomal ATPase PEX6", "gene_name": "pex6", "organism": "Zebrafish", "refseq_name": "peroxisome biogenesis factor 6 isoform X1", "refseq_ac": [ { "id": "XP_001332652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001332652", "type": "external" } ], "gene_names_uniprotkb": "pex6", "gene_names_refseq": "pex6", "protein_names_uniprotkb": "Peroxisomal ATPase PEX6; Peroxin-6; Peroxisomal biogenesis factor 6", "protein_names_refseq": "peroxisome biogenesis factor 6 isoform X1", "tax_id": 7955, "disease": "peroxisome biogenesis disorder 4A (Disease Ontology:DOID:0080479); Heimler syndrome 2 (Disease Ontology:DOID:0080624); Peroxisome biogenesis disorder 4B (Disease Ontology:DOID:0081433)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001332652.5. COMPLETENESS: full length., [RefSeq]; Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling. Specifically recognizes PEX5 monoubiquitinated at 'Cys-11', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel. Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B693-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5A6-1", "uniprot_id": [ { "id": "A0ACD6B5A6_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5A6", "type": "external" } ], "mass": 65583.0, "length": 585, "protein_name": "heparosan-N-sulfate-glucuronate 5-epimerase", "gene_name": "glcea", "organism": "Zebrafish", "refseq_name": "glucuronic acid epimerase a isoform X1", "refseq_ac": [ { "id": "XP_017209557", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209557", "type": "external" } ], "gene_names_uniprotkb": "glcea; glcel; sb:eu394; zgc:136701", "gene_names_refseq": "glcea; glcel; sb:eu394; zgc:136701", "protein_names_uniprotkb": "heparosan-N-sulfate-glucuronate 5-epimerase; 5.1.3.17", "protein_names_refseq": "glucuronic acid epimerase a isoform X1", "tax_id": 7955, "disease": "hypertension (Disease Ontology:DOID:10763); cerebrovascular disease (Disease Ontology:DOID:6713)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017209557.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.1.3.17", "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.3.17", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5A6-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6C1-1", "uniprot_id": [ { "id": "A0ACD6B6C1_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6C1", "type": "external" } ], "mass": 77885.0, "length": 728, "protein_name": "G2 and S phase-expressed protein 1 isoform X1", "gene_name": "gtse1", "organism": "Zebrafish", "refseq_name": "G2 and S phase-expressed protein 1 isoform X1", "refseq_ac": [ { "id": "XP_005163070", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005163070", "type": "external" } ], "gene_names_uniprotkb": "gtse1; fb70b04; fj88g09; wu:fb70b04; wu:fj88g09; wu:fy65d12; zgc:110687", "gene_names_refseq": "fb70b04; fj88g09; gtse1; wu:fb70b04; wu:fj88g09; wu:fy65d12; zgc:110687", "protein_names_uniprotkb": "G2 and S phase-expressed protein 1 isoform X1", "protein_names_refseq": "G2 and S phase-expressed protein 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005163070.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6C1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B714-1", "uniprot_id": [ { "id": "A0ACD6B714_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B714", "type": "external" } ], "mass": 46162.0, "length": 400, "protein_name": "G/T mismatch-specific thymine DNA glycosylase", "gene_name": "tdg.2", "organism": "Zebrafish", "refseq_name": "G/T mismatch-specific thymine DNA glycosylase isoform X1", "refseq_ac": [ { "id": "XP_687336", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687336", "type": "external" } ], "gene_names_uniprotkb": "tdg.2", "gene_names_refseq": "tdg.2", "protein_names_uniprotkb": "G/T mismatch-specific thymine DNA glycosylase; 3.2.2.29; Thymine-DNA glycosylase", "protein_names_refseq": "G/T mismatch-specific thymine DNA glycosylase isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_687336.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B714-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6X6-1", "uniprot_id": [ { "id": "A0ACD6B6X6_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6X6", "type": "external" } ], "mass": 221396.0, "length": 1925, "protein_name": "Dedicator of cytokinesis protein 4 isoform X1", "gene_name": "dock4a", "organism": "Zebrafish", "refseq_name": "dedicator of cytokinesis protein 4 isoform X1", "refseq_ac": [ { "id": "XP_005170755", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170755", "type": "external" } ], "gene_names_uniprotkb": "dock4a", "gene_names_refseq": "dock4a", "protein_names_uniprotkb": "Dedicator of cytokinesis protein 4 isoform X1", "protein_names_refseq": "dedicator of cytokinesis protein 4 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005170755.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6X6-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6U0-1", "uniprot_id": [ { "id": "A0ACD6B6U0_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6U0", "type": "external" } ], "mass": 133186.0, "length": 1206, "protein_name": "Sal-like protein 1", "gene_name": "sall1b", "organism": "Zebrafish", "refseq_name": "sal-like protein 1 isoform X1", "refseq_ac": [ { "id": "XP_005163246", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005163246", "type": "external" } ], "gene_names_uniprotkb": "sall1b", "gene_names_refseq": "sall1b", "protein_names_uniprotkb": "Sal-like protein 1", "protein_names_refseq": "sal-like protein 1 isoform X1", "tax_id": 7955, "disease": "Townes-Brocks syndrome (Disease Ontology:DOID:0050887); middle lobe syndrome (Disease Ontology:DOID:2810); carcinoma (Disease Ontology:DOID:305); renal Wilms' tumor (Disease Ontology:DOID:5176); hepatoblastoma (Disease Ontology:DOID:687); chronic kidney disease (Disease Ontology:DOID:784)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005163246.1. COMPLETENESS: full length., [RefSeq]; Transcriptional repressor involved in organogenesis. Plays an essential role in ureteric bud invasion during kidney development., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6U0-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6N6-1", "uniprot_id": [ { "id": "A0ACD6B6N6_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6N6", "type": "external" } ], "mass": 56775.0, "length": 501, "protein_name": "adenosine deaminase", "gene_name": "ada2b", "organism": "Zebrafish", "refseq_name": "adenosine deaminase 2-A isoform X1", "refseq_ac": [ { "id": "XP_687719", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687719", "type": "external" } ], "gene_names_uniprotkb": "ada2b", "gene_names_refseq": "ada2b", "protein_names_uniprotkb": "adenosine deaminase; 3.5.4.4", "protein_names_refseq": "adenosine deaminase 2-A isoform X1", "tax_id": 7955, "disease": "pleural tuberculosis (Disease Ontology:DOID:106); Sneddon syndrome (Disease Ontology:DOID:13096); pulmonary tuberculosis (Disease Ontology:DOID:2957); adenosine deaminase deficiency (Disease Ontology:DOID:5810)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_687719.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.4", "type": "external" }, { "id": "2.4.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.1", "type": "external" }, { "id": "2.4.2.28", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.28", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6N6-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6F4-1", "uniprot_id": [ { "id": "A0ACD6B6F4_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6F4", "type": "external" } ], "mass": 74039.0, "length": 660, "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "acox1", "organism": "Zebrafish", "refseq_name": "peroxisomal acyl-coenzyme A oxidase 1 isoform X1", "refseq_ac": [ { "id": "XP_005166222", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166222", "type": "external" } ], "gene_names_uniprotkb": "acox1; wu:fb59h12; zgc:114033; zgc:92584", "gene_names_refseq": "acox1; wu:fb59h12; zgc:114033; zgc:92584", "protein_names_uniprotkb": "Acyl-coenzyme A oxidase", "protein_names_refseq": "peroxisomal acyl-coenzyme A oxidase 1 isoform X1", "tax_id": 7955, "disease": "peroxisomal acyl-CoA oxidase deficiency (Disease Ontology:DOID:0050797); Mitchell syndrome (Disease Ontology:DOID:0070516); steatotic liver disease (Disease Ontology:DOID:9452); obesity (Disease Ontology:DOID:9970)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005166222.1. COMPLETENESS: full length., [RefSeq]; Involved in the initial and rate-limiting step of peroxisomal beta-oxidation of straight-chain saturated and unsaturated very-long-chain fatty acids. Catalyzes the desaturation of fatty acyl-CoAs that have a saturated bond between C2 and C3 (2,3-saturated acyl-CoA) to 2-trans-enoyl-CoAs ((2E)-enoyl-CoAs), and donates electrons directly to molecular oxygen (O(2)), thereby producing hydrogen peroxide (H(2)O(2))., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6F4-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5H9-1", "uniprot_id": [ { "id": "A0ACD6B5H9_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5H9", "type": "external" } ], "mass": 151415.0, "length": 1374, "protein_name": "Sushi, nidogen and EGF-like domain-containing protein 1 isoform X1", "gene_name": "sned1", "organism": "Zebrafish", "refseq_name": "sushi, nidogen and EGF-like domain-containing protein 1 isoform X1", "refseq_ac": [ { "id": "XP_017212114", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212114", "type": "external" } ], "gene_names_uniprotkb": "sned1", "gene_names_refseq": "sned1", "protein_names_uniprotkb": "Sushi, nidogen and EGF-like domain-containing protein 1 isoform X1", "protein_names_refseq": "sushi, nidogen and EGF-like domain-containing protein 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017212114.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5H9-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B682-1", "uniprot_id": [ { "id": "A0ACD6B682_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B682", "type": "external" } ], "mass": 53128.0, "length": 474, "protein_name": "Growth/differentiation factor 5 isoform X1", "gene_name": "gdf5", "organism": "Zebrafish", "refseq_name": "growth/differentiation factor 5 isoform X1", "refseq_ac": [ { "id": "XP_073810845", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073810845", "type": "external" } ], "gene_names_uniprotkb": "gdf5", "gene_names_refseq": "gdf5", "protein_names_uniprotkb": "Growth/differentiation factor 5 isoform X1", "protein_names_refseq": "growth/differentiation factor 5 isoform X1", "tax_id": 7955, "disease": "fibular hypoplasia and complex brachydactyly (Disease Ontology:DOID:0050790); multiple synostoses syndrome (Disease Ontology:DOID:0050794); developmental dysplasia of the hip 1 (Disease Ontology:DOID:0060931); acromesomelic dysplasia, Hunter-Thompson type (Disease Ontology:DOID:0080051); acromesomelic dysplasia, Grebe type (Disease Ontology:DOID:0080052); proximal symphalangism 2 (Disease Ontology:DOID:0080788); multiple synostoses syndrome 1 (Disease Ontology:DOID:0081317); multiple synostoses syndrome 2 (Disease Ontology:DOID:0081318); brachydactyly type A1 (Disease Ontology:DOID:0110964); brachydactyly type A2 (Disease Ontology:DOID:0110965); brachydactyly type C (Disease Ontology:DOID:0110970); brachydactyly type A1C (Disease Ontology:DOID:0110977); Parkinson's disease (Disease Ontology:DOID:14330); osteoarthritis (Disease Ontology:DOID:8398)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 14, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58JWH1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B682-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5F2-1", "uniprot_id": [ { "id": "A0ACD6B5F2_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5F2", "type": "external" } ], "mass": 121676.0, "length": 1092, "protein_name": "Integrin alpha-6 isoform X1", "gene_name": "itga6a", "organism": "Zebrafish", "refseq_name": "integrin alpha-6 isoform X1", "refseq_ac": [ { "id": "XP_005167466", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167466", "type": "external" } ], "gene_names_uniprotkb": "itga6a", "gene_names_refseq": "itga6a", "protein_names_uniprotkb": "Integrin alpha-6 isoform X1", "protein_names_refseq": "integrin alpha-6 isoform X1", "tax_id": 7955, "disease": "junctional epidermolysis bullosa with pyloric atresia (Disease Ontology:DOID:0060733); junctional epidermolysis bullosa Herlitz type (Disease Ontology:DOID:0060737); junctional epidermolysis bullosa (Disease Ontology:DOID:3209)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005167466.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5F2-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5M5-1", "uniprot_id": [ { "id": "A0ACD6B5M5_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5M5", "type": "external" } ], "mass": 128657.0, "length": 1184, "protein_name": "Protein transport protein Sec24B isoform X1", "gene_name": "sec24b", "organism": "Zebrafish", "refseq_name": "protein transport protein Sec24B isoform X1", "refseq_ac": [ { "id": "XP_001921634", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001921634", "type": "external" } ], "gene_names_uniprotkb": "sec24b", "gene_names_refseq": "sec24b", "protein_names_uniprotkb": "Protein transport protein Sec24B isoform X1", "protein_names_refseq": "protein transport protein Sec24B isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001921634.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5M5-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5A8-1", "uniprot_id": [ { "id": "A0ACD6B5A8_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5A8", "type": "external" } ], "mass": 52382.0, "length": 507, "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "nup62l", "organism": "Zebrafish", "refseq_name": "nucleoporin 62 like", "refseq_ac": [ { "id": "NP_001107068", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107068", "type": "external" } ], "gene_names_uniprotkb": "nup62l; fb13d02; wu:fb13d02; zgc:172056", "gene_names_refseq": "fb13d02; nup62l; wu:fb13d02; zgc:172056", "protein_names_uniprotkb": "Nuclear pore glycoprotein p62; 62 kDa nucleoporin; Nucleoporin Nup62", "protein_names_refseq": "nucleoporin 62 like", "tax_id": 7955, "disease": "primary biliary cholangitis (Disease Ontology:DOID:12236); striatonigral degeneration (Disease Ontology:DOID:4751)", "pathway": " (dre:563392)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "25605329;31492028;34722501;36493774;8373170", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC154513.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC154513.1. On Jan 20, 2008 this sequence version replaced XP_709603.2., [RefSeq]; Essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex. Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation. It might be involved in protein recruitment to the centrosome after nuclear breakdown., [UniProtKB, UniProtKB, UniProtKB]; Nup62l regulates dorsoventral patterning, gastrula convergence and extension movements, and proper specification of midline organ precursors through mediating the nuclear import of beta-catenins in zebrafish., [RefSeq, PubMed]; Regulation of Wnt/beta-catenin activity by Nup62l is crucial for pharyngeal formation in zebrafish. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0017056 structural constituent of nuclear pore", "go_cellular_component": "GO:0000922 spindle pole;GO:0005813 centrosome;GO:0031965 nuclear membrane;GO:0044613 nuclear pore central transport channel", "go_biological_process": "GO:0001889 liver development;GO:0007507 heart development;GO:0030514 negative regulation of BMP signaling pathway;GO:0060070 canonical Wnt signaling pathway;GO:0090263 positive regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0ACD6B5A8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B625-1", "uniprot_id": [ { "id": "A0ACD6B625_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B625", "type": "external" } ], "mass": 31912.0, "length": 280, "protein_name": "Four and a half LIM domains protein 1", "gene_name": "fhl1b", "organism": "Zebrafish", "refseq_name": "four and a half LIM domains protein 1b isoform X1", "refseq_ac": [ { "id": "XP_009303585", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303585", "type": "external" } ], "gene_names_uniprotkb": "fhl1b; cb1039; fhl", "gene_names_refseq": "cb1039; fhl1b; fhl", "protein_names_uniprotkb": "Four and a half LIM domains protein 1", "protein_names_refseq": "four and a half LIM domains protein 1b isoform X1", "tax_id": 7955, "disease": "scapuloperoneal myopathy (Disease Ontology:DOID:0060253); X-linked Emery-Dreifuss muscular dystrophy 6 (Disease Ontology:DOID:0070251); reducing body myopathy 1A (Disease Ontology:DOID:0080090); reducing body myopathy 1B (Disease Ontology:DOID:0080687); Uruguay faciocardiomusculoskeletal syndrome (Disease Ontology:DOID:0112148); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009303585.1. COMPLETENESS: full length., [RefSeq]; May have an involvement in muscle development or hypertrophy. Isoform 2 binds to RBP-J and plays a negative regulatory role in the RBP-J-mediated transcription in mammalian systems., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B625-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B786-1", "uniprot_id": [ { "id": "A0ACD6B786_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B786", "type": "external" } ], "mass": 310314.0, "length": 2868, "protein_name": "Fibrillin-2b isoform X1", "gene_name": "fbn3", "organism": "Zebrafish", "refseq_name": "fibrillin-2b isoform X1", "refseq_ac": [ { "id": "XP_021325049", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325049", "type": "external" } ], "gene_names_uniprotkb": "fbn3; fbn2b; fbn2", "gene_names_refseq": "fbn2b; fbn2", "protein_names_uniprotkb": "Fibrillin-2b isoform X1", "protein_names_refseq": "fibrillin-2b isoform X1", "tax_id": 7955, "disease": "distal arthrogryposis (Disease Ontology:DOID:0050646); scoliosis (Disease Ontology:DOID:0060249); congenital contractural arachnodactyly (Disease Ontology:DOID:0111595); connective tissue disease (Disease Ontology:DOID:65)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021325049.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B786-1", "record_type": "protein", "filter_code": "0000000.0000010.001000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7D0-1", "uniprot_id": [ { "id": "A0ACD6B7D0_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7D0", "type": "external" } ], "mass": 52216.0, "length": 489, "protein_name": "Zinc finger protein GLIS2", "gene_name": "glis2b", "organism": "Zebrafish", "refseq_name": "zinc finger protein GLIS2b isoform X1", "refseq_ac": [ { "id": "XP_021324946", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324946", "type": "external" } ], "gene_names_uniprotkb": "glis2b; si:rp71-84k24.2", "gene_names_refseq": "glis2b; si:rp71-84k24.2", "protein_names_uniprotkb": "Zinc finger protein GLIS2; GLI-similar 2; Neuronal Krueppel-like protein", "protein_names_refseq": "zinc finger protein GLIS2b isoform X1", "tax_id": 7955, "disease": "nephronophthisis 7 (Disease Ontology:DOID:0111116)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021324946.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7D0-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7G9-1", "uniprot_id": [ { "id": "A0ACD6B7G9_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7G9", "type": "external" } ], "mass": 176417.0, "length": 1570, "protein_name": "Uncharacterized protein zbtb4", "gene_name": "zbtb4", "organism": "Zebrafish", "refseq_name": "uncharacterized protein zbtb4", "refseq_ac": [ { "id": "XP_001339146", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001339146", "type": "external" } ], "gene_names_uniprotkb": "zbtb4", "gene_names_refseq": "zbtb4", "protein_names_uniprotkb": "Uncharacterized protein zbtb4", "protein_names_refseq": "uncharacterized protein zbtb4", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001339146.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7G9-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58GPE1-1", "uniprot_id": [ { "id": "A0AC58GPE1_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58GPE1", "type": "external" } ], "mass": 92366.0, "length": 878, "protein_name": "Premelanosome protein a isoform X1", "gene_name": "pmela", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "pmela; cb397; fdv; pmel17; pmel1a; sb:cb397; silva; wu:fc11g11; wu:fj24g11; zgc:136622", "gene_names_refseq": "", "protein_names_uniprotkb": "Premelanosome protein a isoform X1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58GPE1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B586-1", "uniprot_id": [ { "id": "A0ACD6B586_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B586", "type": "external" } ], "mass": 56028.0, "length": 504, "protein_name": "Solute carrier family 3 member 2b isoform X1", "gene_name": "slc3a2b", "organism": "Zebrafish", "refseq_name": "solute carrier family 3 member 2b isoform X1", "refseq_ac": [ { "id": "XP_005161394", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161394", "type": "external" } ], "gene_names_uniprotkb": "slc3a2b; id:ibd1327; sb:cb519; wu:fe14a07; wu:fq18d12; zgc:55813", "gene_names_refseq": "id:ibd1327; sb:cb519; slc3a2b; wu:fe14a07; wu:fq18d12; zgc:55813", "protein_names_uniprotkb": "Solute carrier family 3 member 2b isoform X1", "protein_names_refseq": "solute carrier family 3 member 2b isoform X1", "tax_id": 7955, "disease": "tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); adenoid cystic carcinoma (Disease Ontology:DOID:0080202); lung pleomorphic carcinoma (Disease Ontology:DOID:0080899); transitional cell carcinoma (Disease Ontology:DOID:2671); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); stomach carcinoma (Disease Ontology:DOID:5517)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005161394.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B586-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5A3-1", "uniprot_id": [ { "id": "A0ACD6B5A3_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5A3", "type": "external" } ], "mass": 35903.0, "length": 320, "protein_name": "Odorant receptor 131-2-like", "gene_name": "or93a1", "organism": "Zebrafish", "refseq_name": "odorant receptor 131-2-like", "refseq_ac": [ { "id": "XP_002665989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002665989", "type": "external" } ], "gene_names_uniprotkb": "or93a1", "gene_names_refseq": "or93a1", "protein_names_uniprotkb": "Odorant receptor 131-2-like", "protein_names_refseq": "odorant receptor 131-2-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_002665989.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5A3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5B1-1", "uniprot_id": [ { "id": "A0ACD6B5B1_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5B1", "type": "external" } ], "mass": 62371.0, "length": 578, "protein_name": "Ran GTPase-activating protein 1", "gene_name": "rangap1b", "organism": "Zebrafish", "refseq_name": "ran GTPase-activating protein 1b isoform X1", "refseq_ac": [ { "id": "XP_073773948", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073773948", "type": "external" } ], "gene_names_uniprotkb": "rangap1b; rangap1; wu:fj57h07; zgc:66165", "gene_names_refseq": "rangap1b; rangap1; wu:fj57h07; zgc:66165", "protein_names_uniprotkb": "Ran GTPase-activating protein 1", "protein_names_refseq": "ran GTPase-activating protein 1b isoform X1", "tax_id": 7955, "disease": "sciatic neuropathy (Disease Ontology:DOID:11446)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58GW48", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5B1-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5B2-1", "uniprot_id": [ { "id": "A0ACD6B5B2_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5B2", "type": "external" } ], "mass": 51573.0, "length": 454, "protein_name": "Hypermethylated in cancer 1 like isoform X1", "gene_name": "hic1l", "organism": "Zebrafish", "refseq_name": "hypermethylated in cancer 1 like", "refseq_ac": [ { "id": "NP_571558", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571558", "type": "external" } ], "gene_names_uniprotkb": "hic1l; etID142640.25; hic1; hzp1; wu:fa03g10; zfHIC1a; zgc:153128", "gene_names_refseq": "etID142640.25; hic1l; hic1; hzp1; wu:fa03g10; zfHIC1a; zgc:153128", "protein_names_uniprotkb": "Hypermethylated in cancer 1 like isoform X1", "protein_names_refseq": "hypermethylated in cancer 1 like; hypermethylated in cancer zinc finger/POZ-domain 1 protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC155218.1, GDQH01003848.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505390, SAMEA4476736 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On Jun 25, 2025 this sequence version replaced NP_571558.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5B2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5B6-1", "uniprot_id": [ { "id": "A0ACD6B5B6_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5B6", "type": "external" } ], "mass": 92433.0, "length": 821, "protein_name": "Circadian locomoter output cycles protein kaput", "gene_name": "clockb", "organism": "Zebrafish", "refseq_name": "clock circadian regulator b", "refseq_ac": [ { "id": "NP_840080", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_840080", "type": "external" } ], "gene_names_uniprotkb": "clockb; clock3; zfClock3", "gene_names_refseq": "clock3; clockb; zfClock3", "protein_names_uniprotkb": "Circadian locomoter output cycles protein kaput", "protein_names_refseq": "Clock1b; circadian locomotor output cycles kaput b; clock circadian regulator b; clock homolog 3", "tax_id": 7955, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); cholestasis (Disease Ontology:DOID:13580); alcohol use disorder (Disease Ontology:DOID:1574); bipolar disorder (Disease Ontology:DOID:3312); sleep disorder (Disease Ontology:DOID:535); diabetes mellitus (Disease Ontology:DOID:9351)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395014.1396606.1, GDQH01015497.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505377, SAMEA3505378 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On or before Jun 10, 2025 this sequence version replaced XP_005168396.2, NP_840080.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5B6-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5C5-1", "uniprot_id": [ { "id": "A0ACD6B5C5_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5C5", "type": "external" } ], "mass": 346322.0, "length": 3119, "protein_name": "FRAS1-related extracellular matrix protein 2a isoform X1", "gene_name": "frem2a", "organism": "Zebrafish", "refseq_name": "FRAS1-related extracellular matrix protein 2a isoform X1", "refseq_ac": [ { "id": "XP_005155437", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155437", "type": "external" } ], "gene_names_uniprotkb": "frem2a; bla", "gene_names_refseq": "bla; frem2a", "protein_names_uniprotkb": "FRAS1-related extracellular matrix protein 2a isoform X1", "protein_names_refseq": "FRAS1-related extracellular matrix protein 2a isoform X1", "tax_id": 7955, "disease": "Fraser syndrome (Disease Ontology:DOID:0090001); Fraser syndrome 2 (Disease Ontology:DOID:0111407); isolated cryptophthalmia (Disease Ontology:DOID:0111717)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005155437.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5C5-1", "record_type": "protein", "filter_code": "0000000.0000010.001000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5C6-1", "uniprot_id": [ { "id": "A0ACD6B5C6_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5C6", "type": "external" } ], "mass": 121567.0, "length": 1079, "protein_name": "DNA annealing helicase and endonuclease ZRANB3", "gene_name": "zranb3", "organism": "Zebrafish", "refseq_name": "DNA annealing helicase and endonuclease ZRANB3", "refseq_ac": [ { "id": "XP_017208927", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208927", "type": "external" } ], "gene_names_uniprotkb": "zranb3", "gene_names_refseq": "zranb3", "protein_names_uniprotkb": "DNA annealing helicase and endonuclease ZRANB3", "protein_names_refseq": "DNA annealing helicase and endonuclease ZRANB3", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017208927.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004519 endonuclease activity;GO:0004386 helicase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5C6-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5D5-1", "uniprot_id": [ { "id": "A0ACD6B5D5_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5D5", "type": "external" } ], "mass": 69221.0, "length": 608, "protein_name": "Leucine zipper putative tumor suppressor 2 homolog", "gene_name": "lzts2b", "organism": "Zebrafish", "refseq_name": "leucine zipper putative tumor suppressor 2 homolog", "refseq_ac": [ { "id": "XP_017214089", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214089", "type": "external" } ], "gene_names_uniprotkb": "lzts2b; LAPSER1; LZTS2", "gene_names_refseq": "lzts2b", "protein_names_uniprotkb": "Leucine zipper putative tumor suppressor 2 homolog; Protein LAPSER1", "protein_names_refseq": "leucine zipper putative tumor suppressor 2 homolog", "tax_id": 7955, "disease": "urinary system disease (Disease Ontology:DOID:18)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017214089.1. COMPLETENESS: full length., [RefSeq]; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5D5-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5F7-1", "uniprot_id": [ { "id": "A0ACD6B5F7_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5F7", "type": "external" } ], "mass": 34322.0, "length": 297, "protein_name": "Syntaxin-12", "gene_name": "stx12l", "organism": "Zebrafish", "refseq_name": "syntaxin-12", "refseq_ac": [ { "id": "XP_697581", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697581", "type": "external" } ], "gene_names_uniprotkb": "stx12l", "gene_names_refseq": "stx12l", "protein_names_uniprotkb": "Syntaxin-12", "protein_names_refseq": "syntaxin-12", "tax_id": 7955, "disease": "cancer (Disease Ontology:DOID:162); carcinoma (Disease Ontology:DOID:305)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_697581.4. COMPLETENESS: full length., [RefSeq]; SNARE promoting fusion of transport vesicles with target membranes. Together with SNARE STX6, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway. Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5F7-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5I8-1", "uniprot_id": [ { "id": "A0ACD6B5I8_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5I8", "type": "external" } ], "mass": 28550.0, "length": 251, "protein_name": "Tumor necrosis factor ligand superfamily member 11", "gene_name": "tnfsf11", "organism": "Zebrafish", "refseq_name": "tumor necrosis factor ligand superfamily member 11", "refseq_ac": [ { "id": "XP_002663397", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002663397", "type": "external" } ], "gene_names_uniprotkb": "tnfsf11", "gene_names_refseq": "tnfsf11", "protein_names_uniprotkb": "Tumor necrosis factor ligand superfamily member 11", "protein_names_refseq": "tumor necrosis factor ligand superfamily member 11", "tax_id": 7955, "disease": "autosomal recessive osteopetrosis 2 (Disease Ontology:DOID:0110943); osteoporosis (Disease Ontology:DOID:11476); myocardial infarction (Disease Ontology:DOID:5844)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_002663397.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5I8-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5L0-1", "uniprot_id": [ { "id": "A0ACD6B5L0_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5L0", "type": "external" } ], "mass": 66624.0, "length": 580, "protein_name": "Interleukin-1 receptor type 1", "gene_name": "zmp:0000000936", "organism": "Zebrafish", "refseq_name": "interleukin-1 receptor type 1", "refseq_ac": [ { "id": "XP_021334731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334731", "type": "external" } ], "gene_names_uniprotkb": "zmp:0000000936", "gene_names_refseq": "zmp:0000000936", "protein_names_uniprotkb": "Interleukin-1 receptor type 1", "protein_names_refseq": "interleukin-1 receptor type 1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021334731.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5L0-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5N0-1", "uniprot_id": [ { "id": "A0ACD6B5N0_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5N0", "type": "external" } ], "mass": 131516.0, "length": 1180, "protein_name": "PDZ domain-containing protein 8", "gene_name": "pdzd8", "organism": "Zebrafish", "refseq_name": "PDZ domain-containing protein 8", "refseq_ac": [ { "id": "XP_689774", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689774", "type": "external" } ], "gene_names_uniprotkb": "pdzd8", "gene_names_refseq": "pdzd8", "protein_names_uniprotkb": "PDZ domain-containing protein 8", "protein_names_refseq": "PDZ domain-containing protein 8", "tax_id": 7955, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_689774.4. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5N0-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5P7-1", "uniprot_id": [ { "id": "A0ACD6B5P7_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5P7", "type": "external" } ], "mass": 84599.0, "length": 780, "protein_name": "ATP-dependent 6-phosphofructokinase", "gene_name": "pfkla", "organism": "Zebrafish", "refseq_name": "ATP-dependent 6-phosphofructokinase, liver type isoform X1", "refseq_ac": [ { "id": "XP_698635", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698635", "type": "external" } ], "gene_names_uniprotkb": "pfkla", "gene_names_refseq": "pfkla", "protein_names_uniprotkb": "ATP-dependent 6-phosphofructokinase; 2.7.1.11; ATP-PFK; Phosphofructokinase; Phosphohexokinase", "protein_names_refseq": "ATP-dependent 6-phosphofructokinase, liver type isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_698635.3. COMPLETENESS: full length., [RefSeq]; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.11", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5P7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5R4-1", "uniprot_id": [ { "id": "A0ACD6B5R4_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5R4", "type": "external" } ], "mass": 90635.0, "length": 813, "protein_name": "Cadherin-like protein 26", "gene_name": "cdh27", "organism": "Zebrafish", "refseq_name": "cadherin-like protein 26", "refseq_ac": [ { "id": "XP_017213763", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213763", "type": "external" } ], "gene_names_uniprotkb": "cdh27", "gene_names_refseq": "cdh27", "protein_names_uniprotkb": "Cadherin-like protein 26", "protein_names_refseq": "cadherin-like protein 26", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017213763.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5R4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5S0-1", "uniprot_id": [ { "id": "A0ACD6B5S0_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5S0", "type": "external" } ], "mass": 64850.0, "length": 585, "protein_name": "T-box brain protein 1 isoform X1", "gene_name": "tbr1a", "organism": "Zebrafish", "refseq_name": "T-box brain protein 1 isoform X1", "refseq_ac": [ { "id": "XP_693121", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693121", "type": "external" } ], "gene_names_uniprotkb": "tbr1a", "gene_names_refseq": "tbr1a", "protein_names_uniprotkb": "T-box brain protein 1 isoform X1", "protein_names_refseq": "T-box brain protein 1 isoform X1", "tax_id": 7955, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_693121.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5S0-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5U3-1", "uniprot_id": [ { "id": "A0ACD6B5U3_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5U3", "type": "external" } ], "mass": 74383.0, "length": 639, "protein_name": "Cyclic nucleotide-gated channel alpha-1", "gene_name": "cnga1b", "organism": "Zebrafish", "refseq_name": "cyclic nucleotide-gated channel alpha-1", "refseq_ac": [ { "id": "XP_701036", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_701036", "type": "external" } ], "gene_names_uniprotkb": "cnga1b", "gene_names_refseq": "cnga1b", "protein_names_uniprotkb": "Cyclic nucleotide-gated channel alpha-1", "protein_names_refseq": "cyclic nucleotide-gated channel alpha-1", "tax_id": 7955, "disease": "retinitis pigmentosa 49 (Disease Ontology:DOID:0110377); retinitis pigmentosa (Disease Ontology:DOID:10584)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_701036.4. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5U3-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5U4-1", "uniprot_id": [ { "id": "A0ACD6B5U4_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5U4", "type": "external" } ], "mass": 58614.0, "length": 504, "protein_name": "Cytochrome P450 7B1", "gene_name": "cyp7b1", "organism": "Zebrafish", "refseq_name": "cytochrome P450 7B1", "refseq_ac": [ { "id": "XP_699028", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_699028", "type": "external" } ], "gene_names_uniprotkb": "cyp7b1", "gene_names_refseq": "cyp7b1", "protein_names_uniprotkb": "Cytochrome P450 7B1", "protein_names_refseq": "cytochrome P450 7B1", "tax_id": 7955, "disease": "hereditary spastic paraplegia 5A (Disease Ontology:DOID:0110810); congenital bile acid synthesis defect 3 (Disease Ontology:DOID:0111070)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_699028.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5U4-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5U6-1", "uniprot_id": [ { "id": "A0ACD6B5U6_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5U6", "type": "external" } ], "mass": 113436.0, "length": 992, "protein_name": "Stromal interaction molecule 2", "gene_name": "stim2a", "organism": "Zebrafish", "refseq_name": "stromal interaction molecule 2", "refseq_ac": [ { "id": "XP_002660454", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002660454", "type": "external" } ], "gene_names_uniprotkb": "stim2a", "gene_names_refseq": "stim2a", "protein_names_uniprotkb": "Stromal interaction molecule 2", "protein_names_refseq": "stromal interaction molecule 2", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_002660454.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5U6-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5W6-1", "uniprot_id": [ { "id": "A0ACD6B5W6_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5W6", "type": "external" } ], "mass": 33390.0, "length": 295, "protein_name": "Ceramide synthase isoform X1", "gene_name": "tlcd3bb", "organism": "Zebrafish", "refseq_name": "ceramide synthase isoform X1", "refseq_ac": [ { "id": "XP_001918966", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001918966", "type": "external" } ], "gene_names_uniprotkb": "tlcd3bb", "gene_names_refseq": "tlcd3bb", "protein_names_uniprotkb": "Ceramide synthase isoform X1", "protein_names_refseq": "ceramide synthase isoform X1", "tax_id": 7955, "disease": "chromosome 16p11.2 deletion syndrome, 593-kb (Disease Ontology:DOID:0070515); cone-rod dystrophy 22 (Disease Ontology:DOID:0081448)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001918966.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5W6-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5W7-1", "uniprot_id": [ { "id": "A0ACD6B5W7_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5W7", "type": "external" } ], "mass": 55936.0, "length": 496, "protein_name": "Ectonucleoside triphosphate diphosphohydrolase 1", "gene_name": "entpd1", "organism": "Zebrafish", "refseq_name": "ectonucleoside triphosphate diphosphohydrolase 1 isoform X1", "refseq_ac": [ { "id": "XP_005156383", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005156383", "type": "external" } ], "gene_names_uniprotkb": "entpd1; zgc:100819", "gene_names_refseq": "entpd1; zgc:100819", "protein_names_uniprotkb": "Ectonucleoside triphosphate diphosphohydrolase 1; 3.6.1.5; ATP diphosphohydrolase; Ecto-ATP diphosphohydrolase 1; Ecto-apyrase; Lymphoid cell activation antigen; Nucleoside triphosphate diphosphohydrolase 1", "protein_names_refseq": "ectonucleoside triphosphate diphosphohydrolase 1 isoform X1", "tax_id": 7955, "disease": "hereditary spastic paraplegia 64 (Disease Ontology:DOID:0110815); pre-eclampsia (Disease Ontology:DOID:10591)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005156383.1. COMPLETENESS: full length., [RefSeq]; Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs). The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates. This activity contributes to the regulation of extracellular levels of nucleotides. By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.6", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.13", "type": "external" }, { "id": "3.6.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.16", "type": "external" }, { "id": "3.6.1.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.53", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5W7-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5X7-1", "uniprot_id": [ { "id": "A0ACD6B5X7_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5X7", "type": "external" } ], "mass": 32526.0, "length": 284, "protein_name": "Syntaxin 2a isoform X1", "gene_name": "stx2a", "organism": "Zebrafish", "refseq_name": "syntaxin 2a isoform X1", "refseq_ac": [ { "id": "XP_005161225", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161225", "type": "external" } ], "gene_names_uniprotkb": "stx2a; fk28f06; wu:fk28f06; zgc:101111", "gene_names_refseq": "fk28f06; stx2a; wu:fk28f06; zgc:101111", "protein_names_uniprotkb": "Syntaxin 2a isoform X1", "protein_names_refseq": "syntaxin 2a isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005161225.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5X7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B5Z6-1", "uniprot_id": [ { "id": "A0ACD6B5Z6_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B5Z6", "type": "external" } ], "mass": 125503.0, "length": 1112, "protein_name": "Protein KIBRA", "gene_name": "wwc1", "organism": "Zebrafish", "refseq_name": "protein KIBRA", "refseq_ac": [ { "id": "XP_689275", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689275", "type": "external" } ], "gene_names_uniprotkb": "wwc1", "gene_names_refseq": "wwc1", "protein_names_uniprotkb": "Protein KIBRA", "protein_names_refseq": "protein KIBRA", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_689275.5. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B5Z6-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B615-1", "uniprot_id": [ { "id": "A0ACD6B615_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B615", "type": "external" } ], "mass": 108253.0, "length": 960, "protein_name": "LIF receptor subunit alpha b isoform X1", "gene_name": "lifrb", "organism": "Zebrafish", "refseq_name": "LIF receptor subunit alpha b isoform X1", "refseq_ac": [ { "id": "XP_009293599", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009293599", "type": "external" } ], "gene_names_uniprotkb": "lifrb; lifr.b; si:dkey-120e24.3", "gene_names_refseq": "lifr.b; lifrb; si:dkey-120e24.3", "protein_names_uniprotkb": "LIF receptor subunit alpha b isoform X1", "protein_names_refseq": "LIF receptor subunit alpha b isoform X1", "tax_id": 7955, "disease": "congenital anomalies of the kidney and urinary tract (Disease Ontology:DOID:0080205); osteochondrodysplasia (Disease Ontology:DOID:2256)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009293599.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B615-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B618-1", "uniprot_id": [ { "id": "A0ACD6B618_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B618", "type": "external" } ], "mass": 113872.0, "length": 1028, "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "rc3h2", "organism": "Zebrafish", "refseq_name": "roquin-2", "refseq_ac": [ { "id": "XP_073770559", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073770559", "type": "external" } ], "gene_names_uniprotkb": "rc3h2", "gene_names_refseq": "rc3h2", "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27", "protein_names_refseq": "roquin-2", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58GLN2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B618-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B632-1", "uniprot_id": [ { "id": "A0ACD6B632_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B632", "type": "external" } ], "mass": 247345.0, "length": 2220, "protein_name": "Plexin-B1", "gene_name": "plxnb1b", "organism": "Zebrafish", "refseq_name": "plexin-B1", "refseq_ac": [ { "id": "XP_003198833", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003198833", "type": "external" } ], "gene_names_uniprotkb": "plxnb1b", "gene_names_refseq": "plxnb1b", "protein_names_uniprotkb": "Plexin-B1", "protein_names_refseq": "plexin-B1", "tax_id": 7955, "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037); obesity (Disease Ontology:DOID:9970)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_003198833.2. COMPLETENESS: full length., [RefSeq]; Receptor for SEMA4D. Plays a role in GABAergic synapse development. Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B632-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B635-1", "uniprot_id": [ { "id": "A0ACD6B635_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B635", "type": "external" } ], "mass": 70533.0, "length": 625, "protein_name": "Kelch-like protein 22", "gene_name": "klhl22", "organism": "Zebrafish", "refseq_name": "kelch-like protein 22", "refseq_ac": [ { "id": "XP_003199199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003199199", "type": "external" } ], "gene_names_uniprotkb": "klhl22", "gene_names_refseq": "klhl22", "protein_names_uniprotkb": "Kelch-like protein 22", "protein_names_refseq": "kelch-like protein 22", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_003199199.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B635-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B636-1", "uniprot_id": [ { "id": "A0ACD6B636_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B636", "type": "external" } ], "mass": 103781.0, "length": 909, "protein_name": "DNA ligase", "gene_name": "lig4", "organism": "Zebrafish", "refseq_name": "DNA ligase 4 isoform X1", "refseq_ac": [ { "id": "XP_005160015", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005160015", "type": "external" } ], "gene_names_uniprotkb": "lig4; zgc:165595", "gene_names_refseq": "lig4; zgc:165595", "protein_names_uniprotkb": "DNA ligase; 6.5.1.1", "protein_names_refseq": "DNA ligase 4 isoform X1", "tax_id": 7955, "disease": "DNA ligase IV deficiency (Disease Ontology:DOID:0060021); prostate cancer (Disease Ontology:DOID:10283); pancreatic cancer (Disease Ontology:DOID:1793); high grade glioma (Disease Ontology:DOID:3070); colorectal cancer (Disease Ontology:DOID:9256); multiple myeloma (Disease Ontology:DOID:9538)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005160015.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016874 ligase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B636-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B637-1", "uniprot_id": [ { "id": "A0ACD6B637_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B637", "type": "external" } ], "mass": 205538.0, "length": 1840, "protein_name": "Protein GREB1", "gene_name": "greb1", "organism": "Zebrafish", "refseq_name": "protein GREB1", "refseq_ac": [ { "id": "XP_005158874", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005158874", "type": "external" } ], "gene_names_uniprotkb": "greb1", "gene_names_refseq": "greb1", "protein_names_uniprotkb": "Protein GREB1", "protein_names_refseq": "protein GREB1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005158874.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B637-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B642-1", "uniprot_id": [ { "id": "A0ACD6B642_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B642", "type": "external" } ], "mass": 227571.0, "length": 2053, "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "nsd1a", "organism": "Zebrafish", "refseq_name": "histone-lysine N-methyltransferase, H3 lysine-36 specific", "refseq_ac": [ { "id": "XP_073778383", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073778383", "type": "external" } ], "gene_names_uniprotkb": "nsd1a", "gene_names_refseq": "nsd1a", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase, H3 lysine-36 specific; 2.1.1.357; H3-K36-HMTase; Nuclear receptor-binding SET domain-containing protein 1", "protein_names_refseq": "histone-lysine N-methyltransferase, H3 lysine-36 specific", "tax_id": 7955, "disease": "Sotos syndrome 1 (Disease Ontology:DOID:0112103); microcephaly (Disease Ontology:DOID:10907); Sotos syndrome (Disease Ontology:DOID:14748); neuroblastoma (Disease Ontology:DOID:769); acute myeloid leukemia (Disease Ontology:DOID:9119)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58H8T3", "ec_number_list": [ { "id": "2.1.1.357", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.357", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B642-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B651-1", "uniprot_id": [ { "id": "A0ACD6B651_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B651", "type": "external" } ], "mass": 83375.0, "length": 721, "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1", "gene_name": "ikbke", "organism": "Zebrafish", "refseq_name": "inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1", "refseq_ac": [ { "id": "XP_005172929", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005172929", "type": "external" } ], "gene_names_uniprotkb": "ikbke; zgc:100844", "gene_names_refseq": "ikbke; zgc:100844", "protein_names_uniprotkb": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1", "protein_names_refseq": "inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005172929.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016301 kinase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B651-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B656-1", "uniprot_id": [ { "id": "A0ACD6B656_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B656", "type": "external" } ], "mass": 46853.0, "length": 418, "protein_name": "Hematopoietic death receptor isoform X1", "gene_name": "hdr", "organism": "Zebrafish", "refseq_name": "hematopoietic death receptor isoform X1", "refseq_ac": [ { "id": "XP_005171855", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171855", "type": "external" } ], "gene_names_uniprotkb": "hdr; ZH-DR; zgc:103531", "gene_names_refseq": "ZH-DR; hdr; zgc:103531", "protein_names_uniprotkb": "Hematopoietic death receptor isoform X1", "protein_names_refseq": "hematopoietic death receptor isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005171855.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B656-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B665-1", "uniprot_id": [ { "id": "A0ACD6B665_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B665", "type": "external" } ], "mass": 33178.0, "length": 294, "protein_name": "Tumor necrosis factor receptor superfamily member 6", "gene_name": "fas", "organism": "Zebrafish", "refseq_name": "tumor necrosis factor receptor superfamily member 6", "refseq_ac": [ { "id": "XP_021323082", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323082", "type": "external" } ], "gene_names_uniprotkb": "fas", "gene_names_refseq": "fas", "protein_names_uniprotkb": "Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor", "protein_names_refseq": "tumor necrosis factor receptor superfamily member 6", "tax_id": 7955, "disease": "adult T-cell leukemia/lymphoma (Disease Ontology:DOID:0050523); chorioamnionitis (Disease Ontology:DOID:0050697); myelodysplastic syndrome (Disease Ontology:DOID:0050908); pre-malignant neoplasm (Disease Ontology:DOID:0060071); brain glioma (Disease Ontology:DOID:0060108); lymphoproliferative syndrome (Disease Ontology:DOID:0060704); alcohol-associated liver disease (Disease Ontology:DOID:0070658); nasal type extranodal NK/T-cell lymphoma (Disease Ontology:DOID:0080797); graft-versus-host disease (Disease Ontology:DOID:0081267); dermatomyositis (Disease Ontology:DOID:10223); prostate cancer (Disease Ontology:DOID:10283); pre-eclampsia (Disease Ontology:DOID:10591); Alzheimer's disease (Disease Ontology:DOID:10652); gastric ulcer (Disease Ontology:DOID:10808); urinary bladder cancer (Disease Ontology:DOID:11054); cryptorchidism (Disease Ontology:DOID:11383); sciatic neuropathy (Disease Ontology:DOID:11446); diabetic angiopathy (Disease Ontology:DOID:11713); primary biliary cholangitis (Disease Ontology:DOID:12236); male infertility (Disease Ontology:DOID:12336); varicocele (Disease Ontology:DOID:12337); alcoholic hepatitis (Disease Ontology:DOID:12351); Graves' disease (Disease Ontology:DOID:12361); aplastic anemia (Disease Ontology:DOID:12449); Huntington's disease (Disease Ontology:DOID:12858); Sjogren's syndrome (Disease Ontology:DOID:12894); dilated cardiomyopathy (Disease Ontology:DOID:12930); HELLP syndrome (Disease Ontology:DOID:13133); Behcet's disease (Disease Ontology:DOID:13241); clonorchiasis (Disease Ontology:DOID:13767); abdominal obesity-metabolic syndrome 1 (Disease Ontology:DOID:14221); Parkinson's disease (Disease Ontology:DOID:14330); cystic fibrosis (Disease Ontology:DOID:1485); breast cancer (Disease Ontology:DOID:1612); glaucoma (Disease Ontology:DOID:1686); melanoma (Disease Ontology:DOID:1909); atherosclerosis (Disease Ontology:DOID:1936); hepatitis B (Disease Ontology:DOID:2043); autoimmune hepatitis (Disease Ontology:DOID:2048); transient cerebral ischemia (Disease Ontology:DOID:224); brain ischemia (Disease Ontology:DOID:2316); multiple sclerosis (Disease Ontology:DOID:2377); relapsing-remitting multiple sclerosis (Disease Ontology:DOID:2378); ovarian cancer (Disease Ontology:DOID:2394); chronic conjunctivitis (Disease Ontology:DOID:2475); transitional cell carcinoma (Disease Ontology:DOID:2671); asthma (Disease Ontology:DOID:2841); IgA glomerulonephritis (Disease Ontology:DOID:2986); acute kidney failure (Disease Ontology:DOID:3021); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); peripheral vascular disease (Disease Ontology:DOID:341); inclusion body myositis (Disease Ontology:DOID:3429); breast carcinoma (Disease Ontology:DOID:3459); mixed connective tissue disease (Disease Ontology:DOID:3492); lung adenocarcinoma (Disease Ontology:DOID:3910); liver disease (Disease Ontology:DOID:409); myasthenia gravis (Disease Ontology:DOID:437); seminoma (Disease Ontology:DOID:4440); macular degeneration (Disease Ontology:DOID:4448); renal cell carcinoma (Disease Ontology:DOID:4450); endophthalmitis (Disease Ontology:DOID:4692); multiple system atrophy (Disease Ontology:DOID:4752); esophagus adenocarcinoma (Disease Ontology:DOID:4914); intrahepatic cholangiocarcinoma (Disease Ontology:DOID:4928); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); retinal detachment (Disease Ontology:DOID:5327); congestive heart failure (Disease Ontology:DOID:6000); autoimmune lymphoproliferative syndrome (Disease Ontology:DOID:6688); hepatocellular carcinoma (Disease Ontology:DOID:684); hepatoblastoma (Disease Ontology:DOID:687); rheumatoid arthritis (Disease Ontology:DOID:7148); retinoblastoma (Disease Ontology:DOID:768); cataract (Disease Ontology:DOID:83); chronic myeloid leukemia (Disease Ontology:DOID:8552); infectious mononucleosis (Disease Ontology:DOID:8568); ulcerative colitis (Disease Ontology:DOID:8577); autoimmune thrombocytopenic purpura (Disease Ontology:DOID:8924); systemic lupus erythematosus (Disease Ontology:DOID:9074); acute myeloid leukemia (Disease Ontology:DOID:9119); Barrett's esophagus (Disease Ontology:DOID:9206); ocular hypertension (Disease Ontology:DOID:9282); type 1 diabetes mellitus (Disease Ontology:DOID:9744); acute lymphoblastic leukemia (Disease Ontology:DOID:9952); heroin dependence (Disease Ontology:DOID:9976)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021323082.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 84, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B665-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B666-1", "uniprot_id": [ { "id": "A0ACD6B666_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B666", "type": "external" } ], "mass": 81236.0, "length": 744, "protein_name": "Tripartite motif-containing protein 2", "gene_name": "trim2a", "organism": "Zebrafish", "refseq_name": "tripartite motif-containing protein 2 isoform X1", "refseq_ac": [ { "id": "XP_005170946", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170946", "type": "external" } ], "gene_names_uniprotkb": "trim2a; trim2; zgc:113099", "gene_names_refseq": "trim2a; trim2; zgc:113099", "protein_names_uniprotkb": "Tripartite motif-containing protein 2; 2.3.2.27; E3 ubiquitin-protein ligase TRIM2; RING-type E3 ubiquitin transferase TRIM2", "protein_names_refseq": "tripartite motif-containing protein 2 isoform X1", "tax_id": 7955, "disease": "Charcot-Marie-Tooth disease type 2R (Disease Ontology:DOID:0110161); autosomal recessive limb-girdle muscular dystrophy (Disease Ontology:DOID:0110274); autosomal recessive limb-girdle muscular dystrophy type 2H (Disease Ontology:DOID:0110282); muscular dystrophy (Disease Ontology:DOID:9884)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005170946.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B666-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B692-1", "uniprot_id": [ { "id": "A0ACD6B692_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B692", "type": "external" } ], "mass": 53573.0, "length": 486, "protein_name": "Alpha-1A adrenergic receptor", "gene_name": "adra1ba", "organism": "Zebrafish", "refseq_name": "alpha-1A adrenergic receptor", "refseq_ac": [ { "id": "XP_001922013", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922013", "type": "external" } ], "gene_names_uniprotkb": "adra1ba", "gene_names_refseq": "adra1ba", "protein_names_uniprotkb": "Alpha-1A adrenergic receptor", "protein_names_refseq": "alpha-1A adrenergic receptor", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001922013.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B692-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6C9-1", "uniprot_id": [ { "id": "A0ACD6B6C9_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6C9", "type": "external" } ], "mass": 61552.0, "length": 533, "protein_name": "Uncharacterized protein si:dkey-187j14.4", "gene_name": "si:dkey-187j14.4", "organism": "Zebrafish", "refseq_name": "uncharacterized protein si:dkey-187j14.4", "refseq_ac": [ { "id": "XP_001345338", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001345338", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-187j14.4", "gene_names_refseq": "si:dkey-187j14.4", "protein_names_uniprotkb": "Uncharacterized protein si:dkey-187j14.4", "protein_names_refseq": "uncharacterized protein si:dkey-187j14.4", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001345338.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6C9-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6E8-1", "uniprot_id": [ { "id": "A0ACD6B6E8_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6E8", "type": "external" } ], "mass": 179549.0, "length": 1587, "protein_name": "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta", "gene_name": "pik3c2b", "organism": "Zebrafish", "refseq_name": "phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta", "refseq_ac": [ { "id": "XP_073772828", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073772828", "type": "external" } ], "gene_names_uniprotkb": "pik3c2b", "gene_names_refseq": "pik3c2b", "protein_names_uniprotkb": "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta", "protein_names_refseq": "phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58GSY0", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6E8-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6E9-1", "uniprot_id": [ { "id": "A0ACD6B6E9_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6E9", "type": "external" } ], "mass": 34309.0, "length": 301, "protein_name": "Junctional adhesion molecule 3B-like", "gene_name": "jam3a", "organism": "Zebrafish", "refseq_name": "junctional adhesion molecule 3B-like", "refseq_ac": [ { "id": "XP_021322068", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322068", "type": "external" } ], "gene_names_uniprotkb": "jam3a", "gene_names_refseq": "jam3a", "protein_names_uniprotkb": "Junctional adhesion molecule 3B-like", "protein_names_refseq": "junctional adhesion molecule 3B-like", "tax_id": 7955, "disease": "sciatic neuropathy (Disease Ontology:DOID:11446); systemic scleroderma (Disease Ontology:DOID:418)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322068.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6E9-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6F5-1", "uniprot_id": [ { "id": "A0ACD6B6F5_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6F5", "type": "external" } ], "mass": 25600.0, "length": 235, "protein_name": "Group XIIB secretory phospholipase A2-like protein", "gene_name": "pla2g12b", "organism": "Zebrafish", "refseq_name": "group XIIB secretory phospholipase A2-like protein isoform 1 precursor", "refseq_ac": [ { "id": "NP_001428967", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428967", "type": "external" } ], "gene_names_uniprotkb": "pla2g12b; wu:fb26d02; wu:fb99g06; wu:fc91d12; zgc:111897; zgc:56487; zgc:77746", "gene_names_refseq": "pla2g12b; wu:fb26d02; wu:fb99g06; wu:fc91d12; zgc:111897; zgc:56487; zgc:77746", "protein_names_uniprotkb": "Group XIIB secretory phospholipase A2-like protein; Group XIII secretory phospholipase A2-like protein; sPLA2-GXIIB", "protein_names_refseq": "group XIIB secretory phospholipase A2-like protein isoform 1 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:406739)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "16109975;19200601;24608635;26469318;29161261;31366908;34783821;35175196;35317738;36961308", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH488985.1, EH494228.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On Jul 21, 2025 this sequence version replaced XP_005156576.2., [RefSeq]; Not known; does not seem to have catalytic activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0004623 phospholipase A2 activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0016042 lipid catabolic process;GO:0050482 arachidonate secretion;GO:0006644 phospholipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "A0ACD6B6F5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6N9-1", "uniprot_id": [ { "id": "A0ACD6B6N9_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6N9", "type": "external" } ], "mass": 85773.0, "length": 750, "protein_name": "Dipeptidyl peptidase 4 isoform X1", "gene_name": "fap", "organism": "Zebrafish", "refseq_name": "dipeptidyl peptidase 4 isoform X1", "refseq_ac": [ { "id": "XP_001920834", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001920834", "type": "external" } ], "gene_names_uniprotkb": "fap", "gene_names_refseq": "fap", "protein_names_uniprotkb": "Dipeptidyl peptidase 4 isoform X1", "protein_names_refseq": "dipeptidyl peptidase 4 isoform X1", "tax_id": 7955, "disease": "esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001920834.4. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6N9-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6P2-1", "uniprot_id": [ { "id": "A0ACD6B6P2_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6P2", "type": "external" } ], "mass": 58765.0, "length": 508, "protein_name": "DNA primase large subunit", "gene_name": "prim2", "organism": "Zebrafish", "refseq_name": "DNA primase large subunit isoform X1", "refseq_ac": [ { "id": "XP_005156868", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005156868", "type": "external" } ], "gene_names_uniprotkb": "prim2; PRIM2A; wu:fa11h04; zgc:110727", "gene_names_refseq": "PRIM2A; prim2; wu:fa11h04; zgc:110727", "protein_names_uniprotkb": "DNA primase large subunit", "protein_names_refseq": "DNA primase large subunit isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005156868.1. COMPLETENESS: full length., [RefSeq]; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6P2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6Q2-1", "uniprot_id": [ { "id": "A0ACD6B6Q2_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6Q2", "type": "external" } ], "mass": 64837.0, "length": 591, "protein_name": "High affinity choline transporter 1", "gene_name": "slc5a7a", "organism": "Zebrafish", "refseq_name": "high affinity choline transporter 1", "refseq_ac": [ { "id": "XP_021332411", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332411", "type": "external" } ], "gene_names_uniprotkb": "slc5a7a", "gene_names_refseq": "slc5a7a", "protein_names_uniprotkb": "High affinity choline transporter 1; Hemicholinium-3-sensitive choline transporter; Solute carrier family 5 member 7", "protein_names_refseq": "high affinity choline transporter 1", "tax_id": 7955, "disease": "congenital myasthenic syndrome 20 (Disease Ontology:DOID:0110661); autosomal dominant distal hereditary motor neuronopathy 7 (Disease Ontology:DOID:0111199); major depressive disorder (Disease Ontology:DOID:1470); depressive disorder (Disease Ontology:DOID:1596)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021332411.1. COMPLETENESS: full length., [RefSeq]; High-affinity Na(+)-coupled choline transmembrane symporter. Functions as an electrogenic, voltage-dependent transporter with variable charge/choline stoichiometry. Choline uptake and choline-induced current is also Cl(-)-dependent where Cl(-) is likely a regulatory ion rather than cotransported ion. Plays a critical role in acetylcholine (ACh) synthesis by taking up the substrate choline from the synaptic cleft into the presynaptic nerve terminals after neurotransmitter release. SLC5A7/CHT1-mediated choline high-affinity transport in cholinergic neurons is the rate-limiting step for production of ACh, thereby facilitating communication by subsequent action potentials. Localized predominantly in presynaptic terminal intracellular organelles, and translocated to the plasma membrane in active form in response to neuronal activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6Q2-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6U5-1", "uniprot_id": [ { "id": "A0ACD6B6U5_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6U5", "type": "external" } ], "mass": 89903.0, "length": 811, "protein_name": "Chloride channel protein", "gene_name": "clcn5b", "organism": "Zebrafish", "refseq_name": "H(+)/Cl(-) exchange transporter 5", "refseq_ac": [ { "id": "XP_685762", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685762", "type": "external" } ], "gene_names_uniprotkb": "clcn5b", "gene_names_refseq": "clcn5b", "protein_names_uniprotkb": "Chloride channel protein", "protein_names_refseq": "H(+)/Cl(-) exchange transporter 5", "tax_id": 7955, "disease": "Dent disease (Disease Ontology:DOID:0050699); X-linked recessive hypophosphatemic rickets (Disease Ontology:DOID:0080353); Dent disease 1 (Disease Ontology:DOID:0081453); X-linked nephrolithiasis type I (Disease Ontology:DOID:0111798); low molecular weight proteinuria with hypercalciuric nephrocalcinosis (Disease Ontology:DOID:0111815)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_685762.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6U5-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6Y6-1", "uniprot_id": [ { "id": "A0ACD6B6Y6_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6Y6", "type": "external" } ], "mass": 50772.0, "length": 464, "protein_name": "hypoxia-inducible factor-proline dioxygenase", "gene_name": "egln2", "organism": "Zebrafish", "refseq_name": "prolyl hydroxylase EGLN2", "refseq_ac": [ { "id": "XP_688016", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688016", "type": "external" } ], "gene_names_uniprotkb": "egln2", "gene_names_refseq": "egln2", "protein_names_uniprotkb": "hypoxia-inducible factor-proline dioxygenase; 1.14.11.29", "protein_names_refseq": "prolyl hydroxylase EGLN2", "tax_id": 7955, "disease": "renal cell carcinoma (Disease Ontology:DOID:4450)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_688016.4. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.29", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.29", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6Y6-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6Z2-1", "uniprot_id": [ { "id": "A0ACD6B6Z2_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6Z2", "type": "external" } ], "mass": 123204.0, "length": 1071, "protein_name": "Guanylate cyclase", "gene_name": "gucy2cb", "organism": "Zebrafish", "refseq_name": "guanylyl cyclase C isoform X1", "refseq_ac": [ { "id": "XP_696628", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696628", "type": "external" } ], "gene_names_uniprotkb": "gucy2cb", "gene_names_refseq": "gucy2cb", "protein_names_uniprotkb": "Guanylate cyclase; 4.6.1.2", "protein_names_refseq": "guanylyl cyclase C isoform X1", "tax_id": 7955, "disease": "abdominal obesity-metabolic syndrome (Disease Ontology:DOID:0060611); congenital diarrhea 6 (Disease Ontology:DOID:0060780); obesity (Disease Ontology:DOID:9970)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_696628.4. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.6.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.2", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6Z2-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B6Z4-1", "uniprot_id": [ { "id": "A0ACD6B6Z4_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B6Z4", "type": "external" } ], "mass": 37382.0, "length": 338, "protein_name": "Mitotic checkpoint protein BUB3", "gene_name": "bub3", "organism": "Zebrafish", "refseq_name": "mitotic checkpoint protein BUB3 isoform X1", "refseq_ac": [ { "id": "XP_005169562", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169562", "type": "external" } ], "gene_names_uniprotkb": "bub3; zgc:101571", "gene_names_refseq": "bub3; zgc:101571", "protein_names_uniprotkb": "Mitotic checkpoint protein BUB3", "protein_names_refseq": "mitotic checkpoint protein BUB3 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005169562.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B6Z4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B735-1", "uniprot_id": [ { "id": "A0ACD6B735_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B735", "type": "external" } ], "mass": 50632.0, "length": 451, "protein_name": "Muscarinic acetylcholine receptor", "gene_name": "chrm4b", "organism": "Zebrafish", "refseq_name": "muscarinic acetylcholine receptor M4", "refseq_ac": [ { "id": "XP_001343971", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001343971", "type": "external" } ], "gene_names_uniprotkb": "chrm4b", "gene_names_refseq": "chrm4b", "protein_names_uniprotkb": "Muscarinic acetylcholine receptor", "protein_names_refseq": "muscarinic acetylcholine receptor M4", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001343971.2. COMPLETENESS: full length., [RefSeq]; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B735-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B757-1", "uniprot_id": [ { "id": "A0ACD6B757_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B757", "type": "external" } ], "mass": 187863.0, "length": 1725, "protein_name": "Inactive tyrosine-protein kinase PEAK1", "gene_name": "peak1", "organism": "Zebrafish", "refseq_name": "inactive tyrosine-protein kinase PEAK1", "refseq_ac": [ { "id": "XP_001921602", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001921602", "type": "external" } ], "gene_names_uniprotkb": "peak1", "gene_names_refseq": "peak1", "protein_names_uniprotkb": "Inactive tyrosine-protein kinase PEAK1; Pseudopodium-enriched atypical kinase 1; Sugen kinase 269; Tyrosine-protein kinase SgK269", "protein_names_refseq": "inactive tyrosine-protein kinase PEAK1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001921602.2. COMPLETENESS: full length., [RefSeq]; Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics. Acts as a scaffold for mediating EGFR signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016301 kinase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B757-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B759-1", "uniprot_id": [ { "id": "A0ACD6B759_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B759", "type": "external" } ], "mass": 102035.0, "length": 920, "protein_name": "phosphatidate phosphatase", "gene_name": "lpin1a", "organism": "Zebrafish", "refseq_name": "phosphatidate phosphatase LPIN1 isoform X1", "refseq_ac": [ { "id": "XP_005158866", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005158866", "type": "external" } ], "gene_names_uniprotkb": "lpin1a; lpin1; zgc:194552; zgc:194558", "gene_names_refseq": "lpin1a; lpin1; zgc:194552; zgc:194558", "protein_names_uniprotkb": "phosphatidate phosphatase; 3.1.3.4", "protein_names_refseq": "phosphatidate phosphatase LPIN1 isoform X1", "tax_id": 7955, "disease": "morbid obesity (Disease Ontology:DOID:11981); lipodystrophy (Disease Ontology:DOID:811)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005158866.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.4", "type": "external" }, { "id": "3.1.3.106", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.106", "type": "external" }, { "id": "3.6.1.75", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.75", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B759-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B767-1", "uniprot_id": [ { "id": "A0ACD6B767_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B767", "type": "external" } ], "mass": 105726.0, "length": 957, "protein_name": "E3 ubiquitin-protein ligase TRIM37", "gene_name": "trim37", "organism": "Zebrafish", "refseq_name": "E3 ubiquitin-protein ligase TRIM37", "refseq_ac": [ { "id": "XP_009303770", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303770", "type": "external" } ], "gene_names_uniprotkb": "trim37", "gene_names_refseq": "trim37", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TRIM37", "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM37", "tax_id": 7955, "disease": "mulibrey nanism (Disease Ontology:DOID:0050436)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009303770.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B767-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B768-1", "uniprot_id": [ { "id": "A0ACD6B768_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B768", "type": "external" } ], "mass": 82839.0, "length": 746, "protein_name": "Zinc finger protein 438 isoform X1", "gene_name": "znf438", "organism": "Zebrafish", "refseq_name": "zinc finger protein 438 isoform X1", "refseq_ac": [ { "id": "XP_009304945", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304945", "type": "external" } ], "gene_names_uniprotkb": "znf438; fi27h05; wu:fi27h05; zfp438; zgc:152875", "gene_names_refseq": "fi27h05; wu:fi27h05; zfp438; zgc:152875; znf438", "protein_names_uniprotkb": "Zinc finger protein 438 isoform X1", "protein_names_refseq": "zinc finger protein 438 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009304945.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B768-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B777-1", "uniprot_id": [ { "id": "A0ACD6B777_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B777", "type": "external" } ], "mass": 52535.0, "length": 463, "protein_name": "Nucleotide exchange factor SIL1", "gene_name": "sil1", "organism": "Zebrafish", "refseq_name": "nucleotide exchange factor SIL1", "refseq_ac": [ { "id": "XP_021336919", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021336919", "type": "external" } ], "gene_names_uniprotkb": "sil1", "gene_names_refseq": "sil1", "protein_names_uniprotkb": "Nucleotide exchange factor SIL1", "protein_names_refseq": "nucleotide exchange factor SIL1", "tax_id": 7955, "disease": "Marinesco-Sjogren syndrome (Disease Ontology:DOID:0080195); primary cerebellar degeneration (Disease Ontology:DOID:9277)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021336919.1. COMPLETENESS: full length., [RefSeq]; Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B777-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B798-1", "uniprot_id": [ { "id": "A0ACD6B798_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B798", "type": "external" } ], "mass": 61295.0, "length": 545, "protein_name": "Neuronal acetylcholine receptor subunit alpha-7", "gene_name": "chrna7b", "organism": "Zebrafish", "refseq_name": "neuronal acetylcholine receptor subunit alpha-7 isoform X1", "refseq_ac": [ { "id": "XP_005174278", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174278", "type": "external" } ], "gene_names_uniprotkb": "chrna7b; LOC101882451", "gene_names_refseq": "LOC101882451", "protein_names_uniprotkb": "Neuronal acetylcholine receptor subunit alpha-7; Nicotinic acetylcholine receptor subunit alpha-7", "protein_names_refseq": "neuronal acetylcholine receptor subunit alpha-7 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005174278.4. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.2", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B798-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7B0-1", "uniprot_id": [ { "id": "A0ACD6B7B0_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7B0", "type": "external" } ], "mass": 190658.0, "length": 1693, "protein_name": "DNA-directed RNA polymerase subunit", "gene_name": "polr1a", "organism": "Zebrafish", "refseq_name": "DNA-directed RNA polymerase I subunit RPA1", "refseq_ac": [ { "id": "XP_001922839", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922839", "type": "external" } ], "gene_names_uniprotkb": "polr1a", "gene_names_refseq": "polr1a", "protein_names_uniprotkb": "DNA-directed RNA polymerase subunit; 2.7.7.6", "protein_names_refseq": "DNA-directed RNA polymerase I subunit RPA1", "tax_id": 7955, "disease": "acrofacial dysostosis Cincinnati type (Disease Ontology:DOID:0060353); hypomyelinating leukodystrophy (Disease Ontology:DOID:0060786)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001922839.2. COMPLETENESS: full length., [RefSeq]; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "GO:0000428 DNA-directed RNA polymerase complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7B0-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7C4-1", "uniprot_id": [ { "id": "A0ACD6B7C4_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7C4", "type": "external" } ], "mass": 81511.0, "length": 731, "protein_name": "Microtubule-associated protein 10", "gene_name": "map10", "organism": "Zebrafish", "refseq_name": "microtubule-associated protein 10", "refseq_ac": [ { "id": "XP_005169615", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169615", "type": "external" } ], "gene_names_uniprotkb": "map10", "gene_names_refseq": "map10", "protein_names_uniprotkb": "Microtubule-associated protein 10", "protein_names_refseq": "microtubule-associated protein 10", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005169615.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7C4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7D6-1", "uniprot_id": [ { "id": "A0ACD6B7D6_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7D6", "type": "external" } ], "mass": 88802.0, "length": 801, "protein_name": "Neurabin-2", "gene_name": "ppp1r9bb", "organism": "Zebrafish", "refseq_name": "neurabin-2", "refseq_ac": [ { "id": "XP_073774354", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073774354", "type": "external" } ], "gene_names_uniprotkb": "ppp1r9bb", "gene_names_refseq": "ppp1r9bb", "protein_names_uniprotkb": "Neurabin-2", "protein_names_refseq": "neurabin-2", "tax_id": 7955, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); schizophrenia (Disease Ontology:DOID:5419); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58GXB2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7D6-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7F7-1", "uniprot_id": [ { "id": "A0ACD6B7F7_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7F7", "type": "external" } ], "mass": 60774.0, "length": 558, "protein_name": "T-complex protein 1 subunit theta", "gene_name": "cct8", "organism": "Zebrafish", "refseq_name": "T-complex protein 1 subunit theta isoform X1", "refseq_ac": [ { "id": "XP_005155423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155423", "type": "external" } ], "gene_names_uniprotkb": "cct8; fa22h09; wu:fa22h09; zgc:56059", "gene_names_refseq": "cct8; fa22h09; wu:fa22h09; zgc:56059", "protein_names_uniprotkb": "T-complex protein 1 subunit theta; CCT-theta", "protein_names_refseq": "T-complex protein 1 subunit theta isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005155423.1. COMPLETENESS: full length., [RefSeq]; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7F7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7G1-1", "uniprot_id": [ { "id": "A0ACD6B7G1_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7G1", "type": "external" } ], "mass": 73085.0, "length": 663, "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "trim32", "organism": "Zebrafish", "refseq_name": "E3 ubiquitin-protein ligase TRIM32 isoform X1", "refseq_ac": [ { "id": "XP_005174738", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174738", "type": "external" } ], "gene_names_uniprotkb": "trim32", "gene_names_refseq": "trim32", "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM32 isoform X1", "tax_id": 7955, "disease": "Bardet-Biedl syndrome 11 (Disease Ontology:DOID:0110133); autosomal recessive limb-girdle muscular dystrophy type 2H (Disease Ontology:DOID:0110282); Bardet-Biedl syndrome (Disease Ontology:DOID:1935); muscular dystrophy (Disease Ontology:DOID:9884)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005174738.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7G1-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G648-1", "uniprot_id": [ { "id": "A0AC58G648_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G648", "type": "external" } ], "mass": 54085.0, "length": 490, "protein_name": "B-cell receptor CD22-like", "gene_name": "LOC101883960", "organism": "Zebrafish", "refseq_name": "B-cell receptor CD22-like", "refseq_ac": [ { "id": "XP_073765201", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765201", "type": "external" } ], "gene_names_uniprotkb": "LOC101883960", "gene_names_refseq": "LOC101883960", "protein_names_uniprotkb": "B-cell receptor CD22-like", "protein_names_refseq": "B-cell receptor CD22-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G648-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G649-1", "uniprot_id": [ { "id": "A0AC58G649_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G649", "type": "external" } ], "mass": 37602.0, "length": 332, "protein_name": "NLR family CARD domain-containing protein 3-like", "gene_name": "LOC108186899", "organism": "Zebrafish", "refseq_name": "NLR family CARD domain-containing protein 3-like", "refseq_ac": [ { "id": "XP_073765204", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765204", "type": "external" } ], "gene_names_uniprotkb": "LOC108186899", "gene_names_refseq": "LOC108186899", "protein_names_uniprotkb": "NLR family CARD domain-containing protein 3-like", "protein_names_refseq": "NLR family CARD domain-containing protein 3-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 17% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. 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This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. 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This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G6A5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G6A6-1", "uniprot_id": [ { "id": "A0AC58G6A6_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G6A6", "type": "external" } ], "mass": 17975.0, "length": 160, "protein_name": "Cytochrome c oxidase subunit", "gene_name": "cox6a1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "cox6a1; ns:zf-e250; zgc:103782", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytochrome c oxidase subunit; Cytochrome c oxidase polypeptide VIa", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G6A6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G6A7-1", "uniprot_id": [ { "id": "A0AC58G6A7_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G6A7", "type": "external" } ], "mass": 46236.0, "length": 448, "protein_name": "Uncharacterized protein", "gene_name": "LOC141375513", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_073765266", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765266", "type": "external" } ], "gene_names_uniprotkb": "LOC141375513", "gene_names_refseq": "LOC141375513", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 15% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G6A7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G6G4-1", "uniprot_id": [ { "id": "A0AC58G6G4_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G6G4", "type": "external" } ], "mass": 49048.0, "length": 450, "protein_name": "5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase", "gene_name": "dcp1a", "organism": "Zebrafish", "refseq_name": "mRNA-decapping enzyme 1A isoform X1", "refseq_ac": [ { "id": "XP_073765299", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765299", "type": "external" } ], "gene_names_uniprotkb": "dcp1a; SMIF; mitc1", "gene_names_refseq": "SMIF; dcp1a; mitc1", "protein_names_uniprotkb": "5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase; 3.6.1.62", "protein_names_refseq": "mRNA-decapping enzyme 1A isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.62", "type": "external" } ], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G6G4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G6M4-1", "uniprot_id": [ { "id": "A0AC58G6M4_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G6M4", "type": "external" } ], "mass": 122507.0, "length": 1069, "protein_name": "Toll-like receptor 9 isoform X1", "gene_name": "tlr9", "organism": "Zebrafish", "refseq_name": "toll-like receptor 9 isoform X1", "refseq_ac": [ { "id": "XP_073765367", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765367", "type": "external" } ], "gene_names_uniprotkb": "tlr9; sb:eu392", "gene_names_refseq": "sb:eu392; tlr9", "protein_names_uniprotkb": "Toll-like receptor 9 isoform X1", "protein_names_refseq": "toll-like receptor 9 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by mRNA evidence. 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This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G6X6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G7I6-1", "uniprot_id": [ { "id": "A0AC58G7I6_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G7I6", "type": "external" } ], "mass": 153657.0, "length": 1378, "protein_name": "Proprotein convertase subtilisin/kexin type 5b isoform X1", "gene_name": "pcsk5b", "organism": "Zebrafish", "refseq_name": "proprotein convertase subtilisin/kexin type 5b isoform X1", "refseq_ac": [ { "id": "XP_073765684", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765684", "type": "external" } ], "gene_names_uniprotkb": "pcsk5b; pcsk5; zgc:165659", "gene_names_refseq": "pcsk5b; pcsk5; zgc:165659", "protein_names_uniprotkb": "Proprotein convertase subtilisin/kexin type 5b isoform X1", "protein_names_refseq": "proprotein convertase subtilisin/kexin type 5b isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G7I6-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0AC58G7W6-1", "uniprot_id": [ { "id": "A0AC58G7W6_DANRE", "url": "https://www.uniprot.org/uniprot/A0AC58G7W6", "type": "external" } ], "mass": 79565.0, "length": 707, "protein_name": "glutamine--fructose-6-phosphate transaminase (isomerizing)", "gene_name": "gfpt1", "organism": "Zebrafish", "refseq_name": "glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 isoform X1", "refseq_ac": [ { "id": "XP_073765827", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073765827", "type": "external" } ], "gene_names_uniprotkb": "gfpt1; hmn; unm_z110", "gene_names_refseq": "gfpt1; hmn; unm_z110", "protein_names_uniprotkb": "glutamine--fructose-6-phosphate transaminase (isomerizing); 2.6.1.16", "protein_names_refseq": "glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008483 transaminase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AC58G7W6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7I4-1", "uniprot_id": [ { "id": "A0ACD6B7I4_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7I4", "type": "external" } ], "mass": 114310.0, "length": 1041, "protein_name": "Calcium-transporting ATPase", "gene_name": "atp2a2b", "organism": "Zebrafish", "refseq_name": "sarcoplasmic/endoplasmic reticulum calcium ATPase 2b isoform X1", "refseq_ac": [ { "id": "XP_005161253", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161253", "type": "external" } ], "gene_names_uniprotkb": "atp2a2b; SERCA2; fb51e04; fb80c02; si:dkey-83d9.6; wu:fb51e04; wu:fb80c02; zK83D9.6", "gene_names_refseq": "SERCA2; atp2a2b; fb51e04; fb80c02; si:dkey-83d9.6; wu:fb51e04; wu:fb80c02; zK83D9.6", "protein_names_uniprotkb": "Calcium-transporting ATPase; 7.2.2.10", "protein_names_refseq": "sarcoplasmic/endoplasmic reticulum calcium ATPase 2b isoform X1", "tax_id": 7955, "disease": "acrokeratosis verruciformis (Disease Ontology:DOID:0050606); essential hypertension (Disease Ontology:DOID:10825); keratosis follicularis (Disease Ontology:DOID:2734); pulmonary hypertension (Disease Ontology:DOID:6432)", "pathway": " (dre:568265)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "22279074;23903933;23966591;25142379;25691335;31171717;31272002;33316259;35829917;36613558", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005161253.1. COMPLETENESS: full length., [RefSeq]; Catalyzes the hydrolysis of ATP coupled with the transport of calcium., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.2.2.10", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.10", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0005388 P-type calcium transporter activity", "go_cellular_component": "GO:0033017 sarcoplasmic reticulum membrane", "go_biological_process": "GO:0061371 determination of heart left/right asymmetry", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "A0ACD6B7I4-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B800-1", "uniprot_id": [ { "id": "A0ACD6B800_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B800", "type": "external" } ], "mass": 96738.0, "length": 847, "protein_name": "Sarcolemmal membrane-associated protein", "gene_name": "slmapa", "organism": "Zebrafish", "refseq_name": "sarcolemma associated protein a isoform X1", "refseq_ac": [ { "id": "XP_005168117", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168117", "type": "external" } ], "gene_names_uniprotkb": "slmapa; fa03e05; fb39b03; wu:fa03e05; wu:fb39b03; zgc:153887", "gene_names_refseq": "fa03e05; fb39b03; slmapa; wu:fa03e05; wu:fb39b03; zgc:153887", "protein_names_uniprotkb": "Sarcolemmal membrane-associated protein", "protein_names_refseq": "sarcolemma associated protein a isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005168117.1. COMPLETENESS: full length., [RefSeq]; Associates with the striatin-interacting phosphatase and kinase (STRIPAK) core complex, forming the extended (SIKE1:SLMAP)STRIPAK complex. The (SIKE1:SLMAP)STRIPAK complex dephosphorylates STK3 leading to the inhibition of Hippo signaling and the control of cell growth. May play a role during myoblast fusion., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005813 centrosome;GO:0031966 mitochondrial membrane;GO:0005789 endoplasmic reticulum membrane;GO:0042383 sarcolemma", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B800-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7Y6-1", "uniprot_id": [ { "id": "A0ACD6B7Y6_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7Y6", "type": "external" } ], "mass": 172321.0, "length": 1540, "protein_name": "Adhesion G protein-coupled receptor L3", "gene_name": "adgrl3.1", "organism": "Zebrafish", "refseq_name": "adhesion G protein-coupled receptor L3 isoform X1", "refseq_ac": [ { "id": "XP_005170997", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170997", "type": "external" } ], "gene_names_uniprotkb": "adgrl3.1", "gene_names_refseq": "adgrl3.1", "protein_names_uniprotkb": "Adhesion G protein-coupled receptor L3; Latrophilin-3", "protein_names_refseq": "adhesion G protein-coupled receptor L3 isoform X1", "tax_id": 7955, "disease": "attention deficit hyperactivity disorder (Disease Ontology:DOID:1094)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005170997.1. COMPLETENESS: full length., [RefSeq]; Orphan adhesion G-protein coupled receptor (aGPCR), which mediates synapse specificity. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. Isoform 1 is specifically coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. Following G-protein coupled receptor activation, undergoes liquid-liquid phase transition, associates with (1) cell adhesion molecules that are expressed at the surface of adjacent cells, as well as (2) PDZ-containing proteins, such as SHANK3 and DLG4, in the cytoplasm to direct synapse formation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0005509 calcium ion binding;GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0030424 axon;GO:0045211 postsynaptic membrane;GO:0070161 anchoring junction", "go_biological_process": "GO:0046959 habituation;GO:0007166 cell surface receptor signaling pathway;GO:0007626 locomotory behavior;GO:0008306 associative learning;GO:0050890 cognition", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7Y6-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7L0-1", "uniprot_id": [ { "id": "A0ACD6B7L0_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7L0", "type": "external" } ], "mass": 141358.0, "length": 1265, "protein_name": "Zinc finger and BTB domain-containing protein 38 isoform X1", "gene_name": "zbtb38", "organism": "Zebrafish", "refseq_name": "zinc finger and BTB domain-containing protein 38 isoform X1", "refseq_ac": [ { "id": "XP_009292090", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009292090", "type": "external" } ], "gene_names_uniprotkb": "zbtb38", "gene_names_refseq": "zbtb38", "protein_names_uniprotkb": "Zinc finger and BTB domain-containing protein 38 isoform X1", "protein_names_refseq": "zinc finger and BTB domain-containing protein 38 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009292090.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7L0-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7V4-1", "uniprot_id": [ { "id": "A0ACD6B7V4_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7V4", "type": "external" } ], "mass": 71228.0, "length": 638, "protein_name": "Forkhead box protein P1a isoform X1", "gene_name": "foxp1a", "organism": "Zebrafish", "refseq_name": "forkhead box protein P1a isoform X1", "refseq_ac": [ { "id": "XP_005162016", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005162016", "type": "external" } ], "gene_names_uniprotkb": "foxp1a; im:7146611; wu:fb97f01; zgc:154010", "gene_names_refseq": "foxp1a; im:7146611; wu:fb97f01; zgc:154010", "protein_names_uniprotkb": "Forkhead box protein P1a isoform X1", "protein_names_refseq": "forkhead box protein P1a isoform X1", "tax_id": 7955, "disease": "complex cortical dysplasia with other brain malformations (Disease Ontology:DOID:0090131); intellectual disability-severe speech delay-mild dysmorphism syndrome (Disease Ontology:DOID:0111331); Huntington's disease (Disease Ontology:DOID:12858); congenital heart disease (Disease Ontology:DOID:1682); lung non-small cell carcinoma (Disease Ontology:DOID:3908); esophagus adenocarcinoma (Disease Ontology:DOID:4914); schizophrenia (Disease Ontology:DOID:5419); congestive heart failure (Disease Ontology:DOID:6000); peritonitis (Disease Ontology:DOID:8283); Barrett's esophagus (Disease Ontology:DOID:9206); hypoplastic left heart syndrome (Disease Ontology:DOID:9955)", "pathway": " (dre:564127)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "15520368;24165894;25556858;26469318;28599080;31917260;34088109;34236575;34650032;36417527", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005162016.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "A0ACD6B7V4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B819-1", "uniprot_id": [ { "id": "A0ACD6B819_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B819", "type": "external" } ], "mass": 55378.0, "length": 493, "protein_name": "Transcription factor EB isoform X1", "gene_name": "tfeb", "organism": "Zebrafish", "refseq_name": "transcription factor EB isoform X1", "refseq_ac": [ { "id": "XP_073772111", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073772111", "type": "external" } ], "gene_names_uniprotkb": "tfeb", "gene_names_refseq": "tfeb", "protein_names_uniprotkb": "Transcription factor EB isoform X1", "protein_names_refseq": "transcription factor EB isoform X1", "tax_id": 7955, "disease": "lysosomal storage disease (Disease Ontology:DOID:3211)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58GQV0", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0022010 central nervous system myelination;GO:0045893 positive regulation of DNA-templated transcription;GO:0006959 humoral immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B819-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7V8-1", "uniprot_id": [ { "id": "A0ACD6B7V8_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7V8", "type": "external" } ], "mass": 75989.0, "length": 678, "protein_name": "Adducin 3 (Gamma) a isoform X1", "gene_name": "add3a", "organism": "Zebrafish", "refseq_name": "adducin 3 (gamma) a isoform 1", "refseq_ac": [ { "id": "NP_001428998", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428998", "type": "external" } ], "gene_names_uniprotkb": "add3a; add3; wu:fb38g03; wu:fc16e06; zgc:55560; zgc:55992; zgc:77226", "gene_names_refseq": "add3a; add3; wu:fb38g03; wu:fc16e06; zgc:55560; zgc:55992; zgc:77226", "protein_names_uniprotkb": "Adducin 3 (Gamma) a isoform X1", "protein_names_refseq": "adducin 3 (gamma) a isoform 1", "tax_id": 7955, "disease": "spastic quadriplegic cerebral palsy 3 (Disease Ontology:DOID:0081361); hypertension (Disease Ontology:DOID:10763); biliary atresia (Disease Ontology:DOID:13608); cerebral palsy (Disease Ontology:DOID:1969); proteinuria (Disease Ontology:DOID:576)", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "20460367;27526058", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588729.18912232.1, SRR32588732.17402732.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476732, SAMEA4476733 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On Jul 22, 2025 this sequence version replaced XP_021325004.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Add3a may be affecting the Hh pathway, an important factor in BA pathogenesis., [RefSeq, PubMed]; Knockdown of miR-143 or disruption of the miR-143-add3 interaction inhibits ventricular cardiomyocyte F-actin remodeling, which blocks their normal growth and elongation and leads to ventricular collapse and decreased contractility., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005516 calmodulin binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane", "go_biological_process": "GO:0061008 hepaticobiliary system development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0ACD6B7V8-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7L2-1", "uniprot_id": [ { "id": "A0ACD6B7L2_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7L2", "type": "external" } ], "mass": 141235.0, "length": 1278, "protein_name": "Cyclin-G-associated kinase", "gene_name": "gak", "organism": "Zebrafish", "refseq_name": "cyclin-G-associated kinase isoform X1", "refseq_ac": [ { "id": "XP_009299489", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009299489", "type": "external" } ], "gene_names_uniprotkb": "gak", "gene_names_refseq": "gak", "protein_names_uniprotkb": "Cyclin-G-associated kinase; 2.7.11.1; DnaJ homolog subfamily C member 26", "protein_names_refseq": "cyclin-G-associated kinase isoform X1", "tax_id": 7955, "disease": "Parkinson's disease 19A (Disease Ontology:DOID:0060891); Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009299489.1. COMPLETENESS: full length., [RefSeq]; Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. May play a role in clathrin-mediated endocytosis and intracellular trafficking, and in the dynamics of clathrin assembly/disassembly., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0016301 kinase activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0005925 focal adhesion;GO:0048471 perinuclear region of cytoplasm;GO:0030136 clathrin-coated vesicle", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7L2-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7I9-1", "uniprot_id": [ { "id": "A0ACD6B7I9_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7I9", "type": "external" } ], "mass": 222650.0, "length": 1955, "protein_name": "Sodium channel protein", "gene_name": "scn1laa", "organism": "Zebrafish", "refseq_name": "sodium channel, voltage-gated, type I-like, alpha isoform X1", "refseq_ac": [ { "id": "XP_017213150", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213150", "type": "external" } ], "gene_names_uniprotkb": "scn1laa; Nav1.1; scn1a; unm_sa1674; zgc:158596; zgc:55600; zscn8", "gene_names_refseq": "Nav1.1; scn1a; scn1laa; unm_sa1674; zgc:158596; zgc:55600; zscn8", "protein_names_uniprotkb": "Sodium channel protein", "protein_names_refseq": "sodium channel, voltage-gated, type I-like, alpha isoform X1", "tax_id": 7955, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); generalized epilepsy with febrile seizures plus (Disease Ontology:DOID:0060170); developmental and epileptic encephalopathy 6B (Disease Ontology:DOID:0070379); Dravet syndrome (Disease Ontology:DOID:0080422); familial hemiplegic migraine 3 (Disease Ontology:DOID:0111183); generalized epilepsy with febrile seizures plus 2 (Disease Ontology:DOID:0111294); epilepsy (Disease Ontology:DOID:1826); brain infarction (Disease Ontology:DOID:3454)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017213150.1. COMPLETENESS: full length., [RefSeq]; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Pore-forming subunit of a voltage-gated sodium (Nav) channel that directly mediates the depolarizing phase of action potentials in excitable membranes. Navs, also called VGSCs (voltage-gated sodium channels) or VDSCs (voltage-dependent sodium channels), operate by switching between closed and open conformations depending on the voltage difference across the membrane. In the open conformation they allow Na(+) ions to selectively pass through the pore, along their electrochemical gradient. The influx of Na+ ions provokes membrane depolarization, initiating the propagation of electrical signals throughout cells and tissues., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.2", "type": "external" } ], "go_molecular_function": "GO:0005248 voltage-gated sodium channel activity", "go_cellular_component": "GO:0001518 voltage-gated sodium channel complex", "go_biological_process": "GO:0034220 monoatomic ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7I9-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7Z7-1", "uniprot_id": [ { "id": "A0ACD6B7Z7_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7Z7", "type": "external" } ], "mass": 170720.0, "length": 1550, "protein_name": "Serine/threonine-protein kinase WNK4", "gene_name": "wnk4b", "organism": "Zebrafish", "refseq_name": "serine/threonine-protein kinase WNK4 isoform X1", "refseq_ac": [ { "id": "XP_685164", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685164", "type": "external" } ], "gene_names_uniprotkb": "wnk4b", "gene_names_refseq": "wnk4b", "protein_names_uniprotkb": "Serine/threonine-protein kinase WNK4; 2.7.11.1; Protein kinase lysine-deficient 4; Protein kinase with no lysine 4", "protein_names_refseq": "serine/threonine-protein kinase WNK4 isoform X1", "tax_id": 7955, "disease": "Gitelman syndrome (Disease Ontology:DOID:0050450); hypertension (Disease Ontology:DOID:10763); pseudohypoaldosteronism (Disease Ontology:DOID:4479)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_685164.4. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "GO:0016301 kinase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7Z7-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7H9-1", "uniprot_id": [ { "id": "A0ACD6B7H9_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7H9", "type": "external" } ], "mass": 222950.0, "length": 1938, "protein_name": "Slow myosin heavy chain 1 isoform X1", "gene_name": "smyhc1", "organism": "Zebrafish", "refseq_name": "slow myosin heavy chain 1 isoform X1", "refseq_ac": [ { "id": "XP_005162977", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005162977", "type": "external" } ], "gene_names_uniprotkb": "smyhc1; fb18g10; im:6897999; wu:fb18g10", "gene_names_refseq": "fb18g10; im:6897999; smyhc1; wu:fb18g10", "protein_names_uniprotkb": "Slow myosin heavy chain 1 isoform X1", "protein_names_refseq": "slow myosin heavy chain 1 isoform X1", "tax_id": 7955, "disease": "distal arthrogryposis (Disease Ontology:DOID:0050646); cardiomyopathy (Disease Ontology:DOID:0050700); intrinsic cardiomyopathy (Disease Ontology:DOID:0060036); distal myopathy 1 (Disease Ontology:DOID:0070197); familial hypertrophic cardiomyopathy (Disease Ontology:DOID:0080326); congenital myopathy 6 (Disease Ontology:DOID:0080719); spondylocarpotarsal synostosis syndrome (Disease Ontology:DOID:0090116); atrial heart septal defect 3 (Disease Ontology:DOID:0110108); hypertrophic cardiomyopathy 1 (Disease Ontology:DOID:0110307); hypertrophic cardiomyopathy 14 (Disease Ontology:DOID:0110320); dilated cardiomyopathy 1EE (Disease Ontology:DOID:0110453); dilated cardiomyopathy 1S (Disease Ontology:DOID:0110454); autosomal recessive hyaline body myopathy (Disease Ontology:DOID:0111268); autosomal dominant hyaline body myopathy (Disease Ontology:DOID:0111269); distal arthrogryposis type 1 (Disease Ontology:DOID:0111596); distal arthrogryposis type 2B3 (Disease Ontology:DOID:0111602); distal arthrogryposis type 2A (Disease Ontology:DOID:0111605); hypertension (Disease Ontology:DOID:10763); heart disease (Disease Ontology:DOID:114); distal myopathy (Disease Ontology:DOID:11720); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); dilated cardiomyopathy (Disease Ontology:DOID:12930); sick sinus syndrome (Disease Ontology:DOID:13884); hypothyroidism (Disease Ontology:DOID:1459); congenital heart disease (Disease Ontology:DOID:1682); atrial heart septal defect (Disease Ontology:DOID:1882); myotonia congenita (Disease Ontology:DOID:2106); inclusion body myositis (Disease Ontology:DOID:3429); Wolff-Parkinson-White syndrome (Disease Ontology:DOID:384); restrictive cardiomyopathy (Disease Ontology:DOID:397); myopathy (Disease Ontology:DOID:423); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); hypoplastic left heart syndrome (Disease Ontology:DOID:9955)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005162977.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 34, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7H9-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7R1-1", "uniprot_id": [ { "id": "A0ACD6B7R1_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7R1", "type": "external" } ], "mass": 36196.0, "length": 327, "protein_name": "Retinol dehydrogenase 1 isoform X1", "gene_name": "rdh1", "organism": "Zebrafish", "refseq_name": "retinol dehydrogenase 1 isoform X1", "refseq_ac": [ { "id": "XP_005167985", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167985", "type": "external" } ], "gene_names_uniprotkb": "rdh1; RDHB", "gene_names_refseq": "RDHB; rdh1", "protein_names_uniprotkb": "Retinol dehydrogenase 1 isoform X1", "protein_names_refseq": "retinol dehydrogenase 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005167985.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7R1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7U6-1", "uniprot_id": [ { "id": "A0ACD6B7U6_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7U6", "type": "external" } ], "mass": 37563.0, "length": 355, "protein_name": "Lysosome-associated membrane glycoprotein 2 isoform X1", "gene_name": "lamp2", "organism": "Zebrafish", "refseq_name": "lysosome-associated membrane glycoprotein 2 isoform 2 precursor", "refseq_ac": [ { "id": "NP_001428472", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428472", "type": "external" } ], "gene_names_uniprotkb": "lamp2; sb:cb587; wu:fb14a06; zgc:103532", "gene_names_refseq": "lamp2; sb:cb587; wu:fb14a06; zgc:103532", "protein_names_uniprotkb": "Lysosome-associated membrane glycoprotein 2 isoform X1", "protein_names_refseq": "lysosomal membrane glycoprotein 2; lysosome-associated membrane glycoprotein 2 isoform 2 precursor", "tax_id": 7955, "disease": "Danon disease (Disease Ontology:DOID:0050437); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395012.1453422.1, SRR26395013.294457.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Jun 13, 2025 this sequence version replaced XP_021336687.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7U6-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7N8-1", "uniprot_id": [ { "id": "A0ACD6B7N8_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7N8", "type": "external" } ], "mass": 39841.0, "length": 353, "protein_name": "Probable G-protein coupled receptor 132", "gene_name": "si:dkey-165a24.9", "organism": "Zebrafish", "refseq_name": "probable G-protein coupled receptor 132", "refseq_ac": [ { "id": "XP_021333458", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333458", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-165a24.9", "gene_names_refseq": "si:dkey-165a24.9", "protein_names_uniprotkb": "Probable G-protein coupled receptor 132", "protein_names_refseq": "probable G-protein coupled receptor 132", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021333458.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AC58G434", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7N8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7P1-1", "uniprot_id": [ { "id": "A0ACD6B7P1_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7P1", "type": "external" } ], "mass": 71405.0, "length": 651, "protein_name": "E3 SUMO-protein ligase PIAS1 isoform X1", "gene_name": "pias1a", "organism": "Zebrafish", "refseq_name": "E3 SUMO-protein ligase PIAS1 isoform X1", "refseq_ac": [ { "id": "XP_692921", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692921", "type": "external" } ], "gene_names_uniprotkb": "pias1a", "gene_names_refseq": "pias1a", "protein_names_uniprotkb": "E3 SUMO-protein ligase PIAS1 isoform X1", "protein_names_refseq": "E3 SUMO-protein ligase PIAS1 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_692921.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016874 ligase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7P1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7P9-1", "uniprot_id": [ { "id": "A0ACD6B7P9_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7P9", "type": "external" } ], "mass": 35252.0, "length": 310, "protein_name": "Odorant receptor 131-2-like", "gene_name": "or137-8", "organism": "Zebrafish", "refseq_name": "odorant receptor 131-2-like", "refseq_ac": [ { "id": "XP_001923221", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001923221", "type": "external" } ], "gene_names_uniprotkb": "or137-8", "gene_names_refseq": "or137-8", "protein_names_uniprotkb": "Odorant receptor 131-2-like", "protein_names_refseq": "odorant receptor 131-2-like", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001923221.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7P9-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7Q1-1", "uniprot_id": [ { "id": "A0ACD6B7Q1_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7Q1", "type": "external" } ], "mass": 515018.0, "length": 4506, "protein_name": "Dynein axonemal heavy chain 2", "gene_name": "dnah2", "organism": "Zebrafish", "refseq_name": "dynein axonemal heavy chain 2", "refseq_ac": [ { "id": "XP_009301399", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301399", "type": "external" } ], "gene_names_uniprotkb": "dnah2", "gene_names_refseq": "dnah2", "protein_names_uniprotkb": "Dynein axonemal heavy chain 2; Axonemal beta dynein heavy chain 2; Ciliary dynein heavy chain 2", "protein_names_refseq": "dynein axonemal heavy chain 2", "tax_id": 7955, "disease": "spermatogenic failure 45 (Disease Ontology:DOID:0112163)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009301399.1. COMPLETENESS: full length., [RefSeq]; As part of the axonemal inner dynein arm complex plays a central role in ciliary beat. Expressed in sperm flagellum, it is required for sperm motility. Dyneins are microtubule-based molecular motors possessing ATPase activities that can convert the chemical energy of ATP into relative sliding between adjacent microtubule doublets to generate ciliary bending., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7Q1-1", "record_type": "protein", "filter_code": "0000000.0000010.000100.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B7Z9-1", "uniprot_id": [ { "id": "A0ACD6B7Z9_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B7Z9", "type": "external" } ], "mass": 12213.0, "length": 102, "protein_name": "C-C motif chemokine 25", "gene_name": "ccl25a", "organism": "Zebrafish", "refseq_name": "C-C motif chemokine 25", "refseq_ac": [ { "id": "XP_002661011", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002661011", "type": "external" } ], "gene_names_uniprotkb": "ccl25a", "gene_names_refseq": "ccl25a", "protein_names_uniprotkb": "C-C motif chemokine 25", "protein_names_refseq": "C-C motif chemokine 25", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_002661011.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B7Z9-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0ACD6B803-1", "uniprot_id": [ { "id": "A0ACD6B803_DANRE", "url": "https://www.uniprot.org/uniprot/A0ACD6B803", "type": "external" } ], "mass": 66720.0, "length": 598, "protein_name": "Large neutral amino acids transporter small subunit 4", "gene_name": "slc43a2b", "organism": "Zebrafish", "refseq_name": "solute carrier family 43 member 2b isoform X1", "refseq_ac": [ { "id": "XP_009303545", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303545", "type": "external" } ], "gene_names_uniprotkb": "slc43a2b; cb941; wu:fb37c04; wu:fb38e03; wu:fb52a10; wu:fi32b04; xx:lithzf000079; zgc:103664", "gene_names_refseq": "cb941; slc43a2b; wu:fb37c04; wu:fb38e03; wu:fb52a10; wu:fi32b04; xx:lithzf000079; zgc:103664", "protein_names_uniprotkb": "Large neutral amino acids transporter small subunit 4; L-type amino acid transporter 4; Solute carrier family 43 member 2", "protein_names_refseq": "solute carrier family 43 member 2b isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009303545.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0ACD6B803-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QUJ1-1", "uniprot_id": [ { "id": "F1QUJ1_DANRE", "url": "https://www.uniprot.org/uniprot/F1QUJ1", "type": "external" } ], "mass": 42915.0, "length": 384, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "dtx3", "organism": "Zebrafish", "refseq_name": "probable E3 ubiquitin-protein ligase DTX3", "refseq_ac": [ { "id": "NP_956822", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956822", "type": "external" } ], "gene_names_uniprotkb": "dtx3; deltex3; fi25g12; wu:fi25g12; zgc:66440", "gene_names_refseq": "deltex3; dtx3; fi25g12; wu:fi25g12; zgc:66440", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.27", "protein_names_refseq": "probable E3 ubiquitin-protein ligase DTX3", "tax_id": 7955, "disease": "", "pathway": " (dre:393500)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "33069857", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC098516.1, GDQH01007128.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On or before Jun 14, 2024 this sequence version replaced XP_009295111.1, NP_956822.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AVB3", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005654 nucleoplasm", "go_biological_process": "GO:0007219 Notch signaling pathway;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1QUJ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0P436-1", "uniprot_id": [ { "id": "TM14C_DANRE", "url": "https://www.uniprot.org/uniprot/Q0P436", "type": "external" } ], "mass": 10681.0, "length": 107, "protein_name": "Transmembrane protein 14C", "gene_name": "tmem14ca; tmem14c", "organism": "Zebrafish", "refseq_name": "transmembrane protein 14C", "refseq_ac": [ { "id": "NP_001038903", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038903", "type": "external" } ], "gene_names_uniprotkb": "tmem14ca; tmem14c; c6orf53; tmem14c; zgc:153439", "gene_names_refseq": "tmem14ca; tmem14c; zgc:153439", "protein_names_uniprotkb": "Transmembrane protein 14C", "protein_names_refseq": "transmembrane protein 14C", "tax_id": 7955, "disease": "", "pathway": " (dre:751728)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "19656490", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC122294.1, EH582080.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC122294.1., [RefSeq]; Required for functional heme biosynthesis in erythroid cells., [RefSeq, PubMed]; Required for normal heme biosynthesis., [UniProtKB, UniProtKB, UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0031966 mitochondrial membrane;GO:0016020 membrane", "go_biological_process": "GO:0006783 heme biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q0P436-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F8W409-1", "uniprot_id": [ { "id": "F8W409_DANRE", "url": "https://www.uniprot.org/uniprot/F8W409", "type": "external" } ], "mass": 178903.0, "length": 1598, "protein_name": "Kinesin-like protein KIF21A isoform X1", "gene_name": "kif21a", "organism": "Zebrafish", "refseq_name": "kinesin-like protein KIF21A isoform X1", "refseq_ac": [ { "id": "XP_009296478", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009296478", "type": "external" } ], "gene_names_uniprotkb": "kif21a", "gene_names_refseq": "kif21a", "protein_names_uniprotkb": "Kinesin-like protein KIF21A isoform X1", "protein_names_refseq": "kinesin-like protein KIF21A isoform X1", "tax_id": 7955, "disease": "congenital fibrosis of the extraocular muscles (Disease Ontology:DOID:0080143); congenital fibrosis of the extraocular muscles 1 (Disease Ontology:DOID:0081015)", "pathway": " (dre:566481)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AZW0", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005874 microtubule;GO:0030425 dendrite;GO:0030426 growth cone;GO:0005737 cytoplasm;GO:0005871 kinesin complex", "go_biological_process": "GO:0007018 microtubule-based movement;GO:0003094 glomerular filtration;GO:0072112 podocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F8W409-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O93375-1", "uniprot_id": [ { "id": "COE2_DANRE", "url": "https://www.uniprot.org/uniprot/O93375", "type": "external" } ], "mass": 63528.0, "length": 579, "protein_name": "Transcription factor COE2", "gene_name": "coe2; ebf2", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "coe2; ebf2; Zcoe2; coe2", "gene_names_refseq": "", "protein_names_uniprotkb": "Transcription factor COE2", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "9784615", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007399 nervous system development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O93375-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "I3ITH4-1", "uniprot_id": [ { "id": "I3ITH4_DANRE", "url": "https://www.uniprot.org/uniprot/I3ITH4", "type": "external" } ], "mass": 223448.0, "length": 2012, "protein_name": "[histone H3]-trimethyl-L-lysine(9) demethylase", "gene_name": "kdm4aa", "organism": "Zebrafish", "refseq_name": "lysine-specific demethylase 4A", "refseq_ac": [ { "id": "NP_001429396", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429396", "type": "external" } ], "gene_names_uniprotkb": "kdm4aa", "gene_names_refseq": "kdm4aa; si:ch211-215f22.3", "protein_names_uniprotkb": "[histone H3]-trimethyl-L-lysine(9) demethylase; 1.14.11.66", "protein_names_refseq": "lysine-specific demethylase 4A", "tax_id": 7955, "disease": "prostate cancer (Disease Ontology:DOID:10283); urinary bladder cancer (Disease Ontology:DOID:11054); lung cancer (Disease Ontology:DOID:1324); breast cancer (Disease Ontology:DOID:1612); stomach carcinoma (Disease Ontology:DOID:5517); alopecia areata (Disease Ontology:DOID:986)", "pathway": " (dre:100003413)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395014.148306.1, SRR26395039.536112.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476729, SAMEA4476736 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On Aug 8, 2025 this sequence version replaced XP_001921829.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QHM2", "ec_number_list": [ { "id": "1.14.11.66", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.66", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0140684 histone H3K9me2/H3K9me3 demethylase activity;GO:0051864 histone H3K36 demethylase activity;GO:0032454 histone H3K9 demethylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006338 chromatin remodeling;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "I3ITH4-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0P4D6-1", "uniprot_id": [ { "id": "TEFM_DANRE", "url": "https://www.uniprot.org/uniprot/Q0P4D6", "type": "external" } ], "mass": 41156.0, "length": 363, "protein_name": "Transcription elongation factor, mitochondrial", "gene_name": "tefm", "organism": "Zebrafish", "refseq_name": "transcription elongation factor, mitochondrial", "refseq_ac": [ { "id": "NP_001073495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073495", "type": "external" } ], "gene_names_uniprotkb": "tefm; si:dkey-10p5.4; zgc:153083", "gene_names_refseq": "tefm; zgc:153083", "protein_names_uniprotkb": "Transcription elongation factor, mitochondrial", "protein_names_refseq": "transcription elongation factor, mitochondrial", "tax_id": 7955, "disease": "combined oxidative phosphorylation deficiency (Disease Ontology:DOID:0060286)", "pathway": " (dre:566236)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;36823193", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC122136.1, CK870749.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC122136.1. On Mar 11, 2007 this sequence version replaced XP_697416.1., [RefSeq]; Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B0R1D7", "ec_number_list": [], "go_molecular_function": "GO:0003676 nucleic acid binding;GO:0003711 transcription elongation factor activity;GO:0003746 translation elongation factor activity", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0042645 mitochondrial nucleoid;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006392 transcription elongation by mitochondrial RNA polymerase;GO:1903109 positive regulation of mitochondrial transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q0P4D6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08C76-1", "uniprot_id": [ { "id": "SSUH2_DANRE", "url": "https://www.uniprot.org/uniprot/Q08C76", "type": "external" } ], "mass": 39475.0, "length": 361, "protein_name": "Protein SSUH2 homolog", "gene_name": "ssuh2rs1; ssuh2", "organism": "Zebrafish", "refseq_name": "protein SSUH2 homolog", "refseq_ac": [ { "id": "NP_001070126", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070126", "type": "external" } ], "gene_names_uniprotkb": "ssuh2rs1; ssuh2; ssuh2rs1; ssuh2; wu:fc17d03; zgc:153440", "gene_names_refseq": "ssuh2rs1; ssuh2; wu:fc17d03; zgc:153440", "protein_names_uniprotkb": "Protein SSUH2 homolog; Protein ssu-2 homolog", "protein_names_refseq": "protein SSUH2 homolog; protein ssu-2 homolog", "tax_id": 7955, "disease": "dentin dysplasia (Disease Ontology:DOID:701)", "pathway": " (dre:767720)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;27680507;40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124353.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC124353.1., [RefSeq]; Plays a role in odontogenesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0R4IG68;F1QCJ3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0042476 odontogenesis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q08C76-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QZX8-1", "uniprot_id": [ { "id": "F1QZX8_DANRE", "url": "https://www.uniprot.org/uniprot/F1QZX8", "type": "external" } ], "mass": 34927.0, "length": 312, "protein_name": "CDKN2A-interacting protein isoform X1", "gene_name": "cdkn2aip", "organism": "Zebrafish", "refseq_name": "CDKN2A-interacting protein isoform X1", "refseq_ac": [ { "id": "XP_005169097", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169097", "type": "external" } ], "gene_names_uniprotkb": "cdkn2aip; zgc:101658", "gene_names_refseq": "cdkn2aip; zgc:101658", "protein_names_uniprotkb": "CDKN2A-interacting protein isoform X1", "protein_names_refseq": "CDKN2A-interacting protein isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:450065)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BGB7", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0090263 positive regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QZX8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1L8P7-1", "uniprot_id": [ { "id": "TSP3B_DANRE", "url": "https://www.uniprot.org/uniprot/Q1L8P7", "type": "external" } ], "mass": 101154.0, "length": 929, "protein_name": "Thrombospondin-3b", "gene_name": "thbs3b", "organism": "Zebrafish", "refseq_name": "thrombospondin-3b precursor", "refseq_ac": [ { "id": "NP_001038679", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038679", "type": "external" } ], "gene_names_uniprotkb": "thbs3b; si:dkey-81h8.2", "gene_names_refseq": "si:dkey-81h8.2; thbs3b", "protein_names_uniprotkb": "Thrombospondin-3b; Thbs3b", "protein_names_refseq": "Tsp-3b; thrombospondin-3b precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:571317)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.1027461.1 [ECO:0000332] RNAseq introns :: partial sample support SAMEA3505370, SAMEA3505371 [ECO:0000350] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000019.1. On Sep 1, 2006 this sequence version replaced XP_699985.1., [RefSeq]; Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix", "go_biological_process": "GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1L8P7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08CM4-1", "uniprot_id": [ { "id": "LIN54_DANRE", "url": "https://www.uniprot.org/uniprot/Q08CM4", "type": "external" } ], "mass": 81389.0, "length": 771, "protein_name": "Protein lin-54 homolog", "gene_name": "lin54", "organism": "Zebrafish", "refseq_name": "protein lin-54 homolog", "refseq_ac": [ { "id": "NP_001070035", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070035", "type": "external" } ], "gene_names_uniprotkb": "lin54; zgc:152921", "gene_names_refseq": "lin54; zgc:152921", "protein_names_uniprotkb": "Protein lin-54 homolog", "protein_names_refseq": "lin-54 homolog; protein lin-54 homolog", "tax_id": 7955, "disease": "", "pathway": " (dre:560688); (R-DRE-1538133)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "18307296", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124175.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC124175.1. On or before Oct 4, 2006 this sequence version replaced XP_707370.1, XP_684211.1., [RefSeq]; Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. Specifically recognizes the consensus motif 5'-TTYRAA-3' in target DNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q08CM4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QZE9-1", "uniprot_id": [ { "id": "TMC2B_DANRE", "url": "https://www.uniprot.org/uniprot/F1QZE9", "type": "external" } ], "mass": 102045.0, "length": 892, "protein_name": "Transmembrane channel-like protein 2-B", "gene_name": "tmc2b", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "tmc2b; si:229d2.2; si:dkey-229d2.2", "gene_names_refseq": "", "protein_names_uniprotkb": "Transmembrane channel-like protein 2-B", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:567304)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;25114259;28534737", "class_list": "", "function": "Probable component of the mechanotransducer (MET) non-selective cation channel., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A076V6D3;F1QW55", "ec_number_list": [], "go_molecular_function": "GO:0008381 mechanosensitive monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0060005 vestibular reflex;GO:0042472 inner ear morphogenesis;GO:0050910 detection of mechanical stimulus involved in sensory perception of sound;GO:0048839 inner ear development;GO:0048884 neuromast development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1QZE9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R8X1-1", "uniprot_id": [ { "id": "F1R8X1_DANRE", "url": "https://www.uniprot.org/uniprot/F1R8X1", "type": "external" } ], "mass": 100498.0, "length": 903, "protein_name": "3.1.3.48; Protein tyrosine phosphatase receptor type Na precursor", "gene_name": "ptprna", "organism": "Zebrafish", "refseq_name": "protein tyrosine phosphatase receptor type Na precursor", "refseq_ac": [ { "id": "NP_001124060", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001124060", "type": "external" } ], "gene_names_uniprotkb": "ptprna; IA-2; fc43c04; ptprn; wu:fc43c04", "gene_names_refseq": "IA-2; fc43c04; ptprna; ptprn; wu:fc43c04", "protein_names_uniprotkb": "3.1.3.48; Protein tyrosine phosphatase receptor type Na precursor", "protein_names_refseq": "protein tyrosine phosphatase receptor type Na precursor; protein tyrosine phosphatase, receptor type, N", "tax_id": 7955, "disease": "type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (dre:324790)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11206415;23974070;26048245;26438539;26469318;27189481;28252024;29860495", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01031820.1, BC163476.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000009.1. On Jan 29, 2016 this sequence version replaced NP_001124060.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the reference genome strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NL05", "ec_number_list": [], "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0030141 secretory granule;GO:0045202 synapse;GO:0030658 transport vesicle membrane", "go_biological_process": "GO:0051046 regulation of secretion;GO:0035773 insulin secretion involved in cellular response to glucose stimulus", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "F1R8X1-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08CB3-1", "uniprot_id": [ { "id": "EVA1A_DANRE", "url": "https://www.uniprot.org/uniprot/Q08CB3", "type": "external" } ], "mass": 17374.0, "length": 153, "protein_name": "Protein eva-1 homolog A", "gene_name": "Eva1a; eva1ab", "organism": "Zebrafish", "refseq_name": "protein eva-1 homolog A", "refseq_ac": [ { "id": "NP_001070055", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070055", "type": "external" } ], "gene_names_uniprotkb": "Eva1a; eva1ab; fam176a; tmem166; zgc:153298", "gene_names_refseq": "eva1ab; eva1a; fam176a; zgc:153298", "protein_names_uniprotkb": "Protein eva-1 homolog A; Protein FAM176A; Transmembrane protein 166", "protein_names_refseq": "eva-1 homolog A; family with sequence similarity 176, member A; protein FAM176A; protein eva-1 homolog A; transmembrane protein 166", "tax_id": 7955, "disease": "", "pathway": " (dre:767647)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01009854.1, GDQH01013009.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505375 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000017.1. On Mar 11, 2009 this sequence version replaced NP_001070055.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:0016020 membrane", "go_biological_process": "GO:0006915 apoptotic process;GO:0006914 autophagy;GO:0031929 TOR signaling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q08CB3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R3W0-1", "uniprot_id": [ { "id": "TAF1B_DANRE", "url": "https://www.uniprot.org/uniprot/F1R3W0", "type": "external" } ], "mass": 66362.0, "length": 576, "protein_name": "TATA box-binding protein-associated factor RNA polymerase I subunit B", "gene_name": "taf1b", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "taf1b; TAFI63; si:dkey-81b15.4; zgc:110402", "gene_names_refseq": "", "protein_names_uniprotkb": "TATA box-binding protein-associated factor RNA polymerase I subunit B; RNA polymerase I-specific TBP-associated factor 63 kDa; TAFI63; TATA box-binding protein-associated factor 1B; TBP-associated factor 1B", "protein_names_refseq": "", "tax_id": 7955, "disease": "mismatch repair cancer syndrome (Disease Ontology:DOID:0112182); Lynch syndrome (Disease Ontology:DOID:3883)", "pathway": " (R-DRE-5250924); (R-DRE-73772); (R-DRE-73863)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "15256591;23594743", "class_list": "", "function": "Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5RIQ5;Q6DRH0", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding", "go_cellular_component": "GO:0005668 RNA polymerase transcription factor SL1 complex;GO:0070860 RNA polymerase I core factor complex", "go_biological_process": "GO:0042790 nucleolar large rRNA transcription by RNA polymerase I;GO:0001188 RNA polymerase I preinitiation complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1R3W0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O42368-1", "uniprot_id": [ { "id": "HXB3A_DANRE", "url": "https://www.uniprot.org/uniprot/O42368", "type": "external" } ], "mass": 44580.0, "length": 417, "protein_name": "Homeobox protein Hox-B3a", "gene_name": "hoxb3a", "organism": "Zebrafish", "refseq_name": "homeobox protein Hox-B3a", "refseq_ac": [ { "id": "NP_571192", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571192", "type": "external" } ], "gene_names_uniprotkb": "hoxb3a; Z-92; hoxb3; id:ibd3053; wu:fc33f11; zgc:111819", "gene_names_refseq": "Z-92; hoxb3a; hoxb3; id:ibd3053; wu:fc33f11; zgc:111819", "protein_names_uniprotkb": "Homeobox protein Hox-B3a; Hox-B3", "protein_names_refseq": "homeo box B3a; homeobox gene B-3; homeobox protein Hox-B3a; hox-B3", "tax_id": 7955, "disease": "", "pathway": " (dre:30339)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15054858;23594743;9425135", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC095559.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC095559.1. On May 29, 2005 this sequence version replaced NP_571192.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4VBK5;Q8AWY5", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0009952 anterior/posterior pattern specification;GO:0048704 embryonic skeletal system morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "O42368-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O42370-1", "uniprot_id": [ { "id": "HXD3A_DANRE", "url": "https://www.uniprot.org/uniprot/O42370", "type": "external" } ], "mass": 43102.0, "length": 396, "protein_name": "Homeobox protein Hox-D3a", "gene_name": "hoxd3a", "organism": "Zebrafish", "refseq_name": "homeobox protein Hox-D3a", "refseq_ac": [ { "id": "NP_571200", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571200", "type": "external" } ], "gene_names_uniprotkb": "hoxd3a; Z-56; hoxd3; im:7144208; si:rp71-78h1.2", "gene_names_refseq": "Z-56; hoxd3a; hoxd3; im:7144208", "protein_names_uniprotkb": "Homeobox protein Hox-D3a; Hox-D3", "protein_names_refseq": "homeo box D3a; homeobox gene D-3; homeobox protein Hox-D3a; hox-D3", "tax_id": 7955, "disease": "", "pathway": " (dre:30349)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;9425135", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.36573331.1, SRR32588734.905123.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505378, SAMEA3505381 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000009.1. On Mar 22, 2009 this sequence version replaced XP_001922751.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B0S5Y4", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0009952 anterior/posterior pattern specification;GO:0048704 embryonic skeletal system morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "O42370-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QRX7-1", "uniprot_id": [ { "id": "TBCD7_DANRE", "url": "https://www.uniprot.org/uniprot/F1QRX7", "type": "external" } ], "mass": 33989.0, "length": 294, "protein_name": "TBC1 domain family member 7", "gene_name": "tbc1d7", "organism": "Zebrafish", "refseq_name": "TBC1 domain family member 7", "refseq_ac": [ { "id": "NP_957071", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957071", "type": "external" } ], "gene_names_uniprotkb": "tbc1d7; zgc:73291", "gene_names_refseq": "tbc1d7; zgc:73291", "protein_names_uniprotkb": "TBC1 domain family member 7", "protein_names_refseq": "TBC1 domain family member 7", "tax_id": 7955, "disease": "", "pathway": " (dre:393750)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.1789469.1, SRR32588730.13417660.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On or before Jun 30, 2025 this sequence version replaced XP_021324055.1, NP_957071.1., [RefSeq]; Non-catalytic component of the TSC-TBC complex, a multiprotein complex that acts as a negative regulator of the canonical mTORC1 complex, an evolutionarily conserved central nutrient sensor that stimulates anabolic reactions and macromolecule biosynthesis to promote cellular biomass generation and growth. The TSC-TBC complex acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. In absence of nutrients, the TSC-TBC complex inhibits mTORC1, thereby preventing phosphorylation of ribosomal protein S6 kinase (RPS6KB1 and RPS6KB2) and EIF4EBP1 (4E-BP1) by the mTORC1 signaling. The TSC-TBC complex is inactivated in response to nutrients, relieving inhibition of mTORC1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6PBQ9", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0062078 TSC1-TSC2 complex binding", "go_cellular_component": "GO:0033596 TSC1-TSC2 complex;GO:0005829 cytosol;GO:0005765 lysosomal membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0032007 negative regulation of TOR signaling;GO:0070848 response to growth factor;GO:0090630 activation of GTPase activity;GO:0009267 cellular response to starvation;GO:1904262 negative regulation of TORC1 signaling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1QRX7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QG18-1", "uniprot_id": [ { "id": "F1QG18_DANRE", "url": "https://www.uniprot.org/uniprot/F1QG18", "type": "external" } ], "mass": 52915.0, "length": 472, "protein_name": "D(3) dopamine receptor", "gene_name": "drd3", "organism": "Zebrafish", "refseq_name": "D(3) dopamine receptor isoform X1", "refseq_ac": [ { "id": "XP_005162730", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005162730", "type": "external" } ], "gene_names_uniprotkb": "drd3", "gene_names_refseq": "drd3", "protein_names_uniprotkb": "D(3) dopamine receptor; Dopamine D3 receptor", "protein_names_refseq": "D(3) dopamine receptor isoform X1", "tax_id": 7955, "disease": "restless legs syndrome (Disease Ontology:DOID:0050425); essential tremor 1 (Disease Ontology:DOID:0111428); Alzheimer's disease (Disease Ontology:DOID:10652); Parkinson's disease (Disease Ontology:DOID:14330); essential tremor (Disease Ontology:DOID:4990); schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (R-DRE-390651); (R-DRE-418594)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Dopamine receptor that is primarily expressed in limbic areas of the brain and is involved in the modulation of cognitive, emotional, and endocrine functions. Plays a key role in regulating neuronal signaling pathways associated with motivation, reward, and behavior. Coupled to G(i)/G(o) proteins; activation leads to inhibition of adenylate cyclase and decreased intracellular cAMP levels. Involved in the control of locomotor activity and implicated in several neuropsychiatric disorders, including schizophrenia and substance use disorders. Promotes cell proliferation through MAP kinase signaling. Also involved in autophagy regulation: receptor activation stimulates AMPK, which phosphorylates RPTOR and enhances its interaction with MTOR, thereby inhibiting MTORC1 signaling and its downstream target RPS6KB1. This leads to activation of ULK1 and initiation of the autophagy cascade. Forms heterotetramers with DRD1 to potentiate beta-arrestin recruitment and mediate locomotor activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B9M1", "ec_number_list": [], "go_molecular_function": "GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go;GO:0004938 alpha2-adrenergic receptor activity;GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse", "go_biological_process": "GO:0045744 negative regulation of G protein-coupled receptor signaling pathway;GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway;GO:0048148 behavioral response to cocaine;GO:0051952 regulation of amine transport;GO:0060158 phospholipase C-activating dopamine receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QG18-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6P6J7-1", "uniprot_id": [ { "id": "F6P6J7_DANRE", "url": "https://www.uniprot.org/uniprot/F6P6J7", "type": "external" } ], "mass": 40616.0, "length": 358, "protein_name": "hypoxia-inducible factor-proline dioxygenase", "gene_name": "egln1b", "organism": "Zebrafish", "refseq_name": "egl nine homolog 1b", "refseq_ac": [ { "id": "NP_001002595", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002595", "type": "external" } ], "gene_names_uniprotkb": "egln1b; egln1; fk45e02; wu:fk45e02; zgc:92314", "gene_names_refseq": "egln1b; egln1; fk45e02; wu:fk45e02; zgc:92314", "protein_names_uniprotkb": "hypoxia-inducible factor-proline dioxygenase; 1.14.11.29", "protein_names_refseq": "Hif-p4h-2; egl nine homolog 1b; egl nine homolog 1", "tax_id": 7955, "disease": "familial erythrocytosis 3 (Disease Ontology:DOID:0080338); renal cell carcinoma (Disease Ontology:DOID:4450); polycythemia (Disease Ontology:DOID:8432)", "pathway": " (dre:436868)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "19304954;20952382;27189481;31780949;32963106;37290634;38492922;39255062", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC076001.1, CK027525.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC076001.1. On Sep 30, 2011 this sequence version replaced NP_001002595.1., [RefSeq]; Zebrafish mutants in egln1 display a hypoxic response and develop polycythemia. Erratum:[Life Sci. 2025 Dec 1;382:124045. doi: 10.1016/j.lfs.2025.124045. PMID: 41152124], [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N0S3", "ec_number_list": [ { "id": "1.14.11.29", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.29", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0008270 zinc ion binding;GO:0031418 L-ascorbic acid binding;GO:0051213 dioxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0048823 nucleate erythrocyte development;GO:0071456 cellular response to hypoxia;GO:0043523 regulation of neuron apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "F6P6J7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QJF4-1", "uniprot_id": [ { "id": "RORAB_DANRE", "url": "https://www.uniprot.org/uniprot/F1QJF4", "type": "external" } ], "mass": 53570.0, "length": 474, "protein_name": "Nuclear receptor ROR-alpha B", "gene_name": "rorab", "organism": "Zebrafish", "refseq_name": "nuclear receptor ROR-alpha B", "refseq_ac": [ { "id": "NP_957361", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957361", "type": "external" } ], "gene_names_uniprotkb": "rorab; Rora; rora1; wu:fq24g04; zgc:55954", "gene_names_refseq": "Rora; rorab; wu:fq24g04; zgc:55954", "protein_names_uniprotkb": "Nuclear receptor ROR-alpha B; Retinoid-related orphan receptor alpha 1; Retinoid-related orphan receptor-alpha B", "protein_names_refseq": "NR1F1-A; RORalpha-A; nuclear receptor ROR-alpha B; retinoid-related orphan receptor alpha 1; retinoid-related orphan receptor-alpha B; rora1", "tax_id": 7955, "disease": "idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); childhood-onset asthma (Disease Ontology:DOID:0080815); nocturnal asthma (Disease Ontology:DOID:0080826); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); coronary artery disease (Disease Ontology:DOID:3393); lung non-small cell carcinoma (Disease Ontology:DOID:3908); tuberculosis (Disease Ontology:DOID:399); allergic rhinitis (Disease Ontology:DOID:4481); myocardial infarction (Disease Ontology:DOID:5844); acute myocardial infarction (Disease Ontology:DOID:9408)", "pathway": " (dre:554722); (R-DRE-383280)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "17685489;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC051158.1, BC159203.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC051158.1. On Feb 21, 2008 this sequence version replaced XP_702442.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) (By similarity). Required for proper cerebellum development (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE). Required for proper cerebellum development., [UniProtKB, UniProtKB, UniProtKB]; Study reports cloning and expression pattern of zebrafish ROR alpha orthologues rora1 and rora2; both rora1 and rora2 are spatially expressed in the retina and tectum, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B0JZJ5;Q7ZU39", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0004879 nuclear receptor activity;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1QJF4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1Q930-1", "uniprot_id": [ { "id": "T237A_DANRE", "url": "https://www.uniprot.org/uniprot/F1Q930", "type": "external" } ], "mass": 42869.0, "length": 377, "protein_name": "Transmembrane protein 237A", "gene_name": "tmem237a", "organism": "Zebrafish", "refseq_name": "transmembrane protein 237A", "refseq_ac": [ { "id": "NP_001306065", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001306065", "type": "external" } ], "gene_names_uniprotkb": "tmem237a; als2cr4a; als2cr4; si:dkey-33m14.6", "gene_names_refseq": "als2cr4a; als2cr4; si:dkey-33m14.6; tmem237a", "protein_names_uniprotkb": "Transmembrane protein 237A; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog A", "protein_names_refseq": "amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4a; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog A; transmembrane protein 237A", "tax_id": 7955, "disease": "Joubert syndrome (Disease Ontology:DOID:0050777); Joubert syndrome 14 (Disease Ontology:DOID:0110983)", "pathway": " (dre:557237)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22152675;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01041107.1, SRR32588722.13710901.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000009.1, EH453111.1 and EH461056.1. On Jan 26, 2016 this sequence version replaced XP_005167559.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Component of the transition zone in primary cilia. Required for ciliogenesis., [UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0035869 ciliary transition zone;GO:0005929 cilium", "go_biological_process": "GO:0060271 cilium assembly;GO:0030111 regulation of Wnt signaling pathway;GO:0060027 convergent extension involved in gastrulation;GO:0030030 cell projection organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1Q930-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O57457-1", "uniprot_id": [ { "id": "E41LA_DANRE", "url": "https://www.uniprot.org/uniprot/O57457", "type": "external" } ], "mass": 70709.0, "length": 619, "protein_name": "Band 4.1-like protein 4", "gene_name": "epb41l4a", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "epb41l4a; EPB41L4; epb4.1l4; fc29f06; nbl4; wu:fc29f06", "gene_names_refseq": "", "protein_names_uniprotkb": "Band 4.1-like protein 4; Erythrocyte membrane protein band 4.1-like 4A; Protein Nbl4", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:30470)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10874211;18442396;26469318;27189481;28252024;9551184", "class_list": "", "function": "Not known, binds calmodulin., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0016020 membrane", "go_biological_process": "GO:0031032 actomyosin structure organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "O57457-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P50541-1", "uniprot_id": [ { "id": "MXI1_DANRE", "url": "https://www.uniprot.org/uniprot/P50541", "type": "external" } ], "mass": 27643.0, "length": 243, "protein_name": "Max-interacting protein 1", "gene_name": "mxi1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "mxi1; etID309773.22; fb16b12; fb55f03; wu:fb16b12; wu:fb55f03; wu:fd06a08; wu:fz74f10", "gene_names_refseq": "", "protein_names_uniprotkb": "Max-interacting protein 1; Max interactor 1", "protein_names_refseq": "", "tax_id": 7955, "disease": "prostate cancer (Disease Ontology:DOID:10283); Parkinson's disease (Disease Ontology:DOID:14330); breast adenocarcinoma (Disease Ontology:DOID:3458); neurofibrosarcoma (Disease Ontology:DOID:3512); esophageal cancer (Disease Ontology:DOID:5041)", "pathway": " (dre:30485)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12949138;19449054;27189481;7835718;7936639", "class_list": "", "function": "Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MXI1 thus antagonizes MYC transcriptional activity by competing for MAX., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P50541-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08C72-1", "uniprot_id": [ { "id": "CWC22_DANRE", "url": "https://www.uniprot.org/uniprot/Q08C72", "type": "external" } ], "mass": 113350.0, "length": 985, "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "cwc22", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "cwc22; fb13g08; fi16b02; ncm; wu:fb13g08; wu:fi16b02; zgc:153452", "gene_names_refseq": "", "protein_names_uniprotkb": "Pre-mRNA-splicing factor CWC22 homolog; Nucampholin homolog", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:566033); (R-DRE-72163)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "23671706;26469318", "class_list": "", "function": "Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0005681 spliceosomal complex;GO:0071013 catalytic step 2 spliceosome;GO:0071006 U2-type catalytic step 1 spliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0006397 mRNA processing;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q08C72-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6NW67-1", "uniprot_id": [ { "id": "F6NW67_DANRE", "url": "https://www.uniprot.org/uniprot/F6NW67", "type": "external" } ], "mass": 37385.0, "length": 341, "protein_name": "Voltage-dependent calcium channel gamma-7 subunit", "gene_name": "cacng7a", "organism": "Zebrafish", "refseq_name": "calcium channel, voltage-dependent, gamma subunit 7a isoform X1", "refseq_ac": [ { "id": "XP_005159461", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005159461", "type": "external" } ], "gene_names_uniprotkb": "cacng7a; si:dkey-21p19.1", "gene_names_refseq": "cacng7a; si:dkey-21p19.1", "protein_names_uniprotkb": "Voltage-dependent calcium channel gamma-7 subunit", "protein_names_refseq": "calcium channel, voltage-dependent, gamma subunit 7a isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100034540)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "27189481;37979715", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B624", "ec_number_list": [], "go_molecular_function": "GO:0005262 calcium channel activity;GO:0005245 voltage-gated calcium channel activity;GO:0016247 channel regulator activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0034702 monoatomic ion channel complex;GO:0032281 AMPA glutamate receptor complex;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:0051968 positive regulation of synaptic transmission, glutamatergic;GO:0019226 transmission of nerve impulse;GO:0098970 postsynaptic neurotransmitter receptor diffusion trapping", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F6NW67-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QD93-1", "uniprot_id": [ { "id": "F1QD93_DANRE", "url": "https://www.uniprot.org/uniprot/F1QD93", "type": "external" } ], "mass": 59099.0, "length": 521, "protein_name": "Serine/threonine-protein phosphatase", "gene_name": "ppp3ca", "organism": "Zebrafish", "refseq_name": "serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform 1", "refseq_ac": [ { "id": "NP_001185479", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185479", "type": "external" } ], "gene_names_uniprotkb": "ppp3ca; fj46e08; si:dkeyp-79c2.2; wu:fj46e08", "gene_names_refseq": "fj46e08; ppp3ca; si:dkeyp-79c2.2; wu:fj46e08", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase; 3.1.3.16", "protein_names_refseq": "serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform 1", "tax_id": 7955, "disease": "developmental and epileptic encephalopathy 91 (Disease Ontology:DOID:0080472); dilated cardiomyopathy (Disease Ontology:DOID:12930); focal segmental glomerulosclerosis (Disease Ontology:DOID:1312); cholangiocarcinoma (Disease Ontology:DOID:4947); schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (dre:794574); (R-DRE-2871809); (R-DRE-4086398); (R-DRE-5607763)", "pathway_count": 4, "publication_count": 6, "publication_id_list": "20652955;26469318;28252024;28826496;33376206;33986646", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588723.1217082.1, SRR32588721.392194.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Oct 24, 2010 this sequence version replaced XP_001334569.3. Sequence Note:., [RefSeq]; The findings reveal a novel mechanism by which Ca2+ overload disrupts myofibril integrity by activating a Calcineurin-FoxO-MuRF1-proteosome signaling pathway. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NVA3", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "GO:0033192 calmodulin-dependent protein phosphatase activity;GO:0005516 calmodulin binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005955 calcineurin complex", "go_biological_process": "GO:0097720 calcineurin-mediated signaling;GO:0033173 calcineurin-NFAT signaling cascade", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F1QD93-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "I3IT74-1", "uniprot_id": [ { "id": "I3IT74_DANRE", "url": "https://www.uniprot.org/uniprot/I3IT74", "type": "external" } ], "mass": 36653.0, "length": 324, "protein_name": "cyclin-dependent kinase", "gene_name": "cdk6", "organism": "Zebrafish", "refseq_name": "cyclin-dependent kinase 6", "refseq_ac": [ { "id": "NP_001137525", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137525", "type": "external" } ], "gene_names_uniprotkb": "cdk6; si:ch211-234f14.1", "gene_names_refseq": "cdk6; si:ch211-234f14.1", "protein_names_uniprotkb": "cyclin-dependent kinase; 2.7.11.22", "protein_names_refseq": "cyclin-dependent kinase 6", "tax_id": 7955, "disease": "medulloblastoma (Disease Ontology:DOID:0050902); primary autosomal recessive microcephaly 12 (Disease Ontology:DOID:0070284); glioblastoma (Disease Ontology:DOID:3068); high grade glioma (Disease Ontology:DOID:3070); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); pancreatic adenocarcinoma (Disease Ontology:DOID:4074); non-functioning pancreatic endocrine tumor (Disease Ontology:DOID:7698)", "pathway": " (dre:100034507); (R-DRE-2559580); (R-DRE-2559582); (R-DRE-2559585); (R-DRE-69231); (R-DRE-8934593); (R-DRE-9754119)", "pathway_count": 7, "publication_count": 10, "publication_id_list": "22538478;22981606;23698347;26161812;26469318;33518044;33548715;33549839;34829928;38321933", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01025707.1, SRR32588731.155218.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505380, SAMEA4476730 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On or before Jul 31, 2025 this sequence version replaced XP_005159752.1, NP_001137525.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; DNA hypomethylation activates Cdk4/6 and Atr to induce DNA replication and cell cycle arrest to constrain liver outgrowth in zebrafish., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B6S8;A0AC58HX06", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0016301 kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005634 nucleus;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:0042127 regulation of cell population proliferation;GO:0051301 cell division;GO:0043697 cell dedifferentiation;GO:0007165 signal transduction;GO:0000086 G2/M transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "I3IT74-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "I3ISS4-1", "uniprot_id": [ { "id": "OXR1B_DANRE", "url": "https://www.uniprot.org/uniprot/I3ISS4", "type": "external" } ], "mass": 93343.0, "length": 841, "protein_name": "Oxidation resistance protein 1B", "gene_name": "oxr1b", "organism": "Zebrafish", "refseq_name": "oxidation resistance protein 1b isoform X1", "refseq_ac": [ { "id": "XP_005159515", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005159515", "type": "external" } ], "gene_names_uniprotkb": "oxr1b; fc07g10; si:dkeyp-84f11.5; wu:fc07g10", "gene_names_refseq": "fc07g10; oxr1b; si:dkeyp-84f11.5; wu:fc07g10", "protein_names_uniprotkb": "Oxidation resistance protein 1B", "protein_names_refseq": "oxidation resistance protein 1b isoform X1", "tax_id": 7955, "disease": "cerebellar hyplasia/atrophy, epilepsy, and global developmental delay (Disease Ontology:DOID:0070339)", "pathway": " (dre:570476)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "15520368;23567754;23594743;26469318;28252024;34111665;36130215;37031846", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Inhibits the activity of the vacuolar-type ATPase (V-ATPase) by inducing disassembly of the V-ATPase complex (By similarity). Protects the Golgi apparatus lumen from excess acidification by inhibiting V-ATPase ATP hydrolytic activity, maintaining optimal conditions for glycosylation enzymes (By similarity). Involved in protection from oxidative damage (PubMed:34111665). Required for correct development of the statoacoustic ganglion of the inner ear (PubMed:36130215)., [UniProtKB, PubMed, UniProtKB, PubMed, UniProtKB]; May be involved in protection from oxidative damage., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B612", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0042981 regulation of apoptotic process;GO:0061550 cranial ganglion development;GO:1902882 regulation of response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "I3ISS4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0P4A6-1", "uniprot_id": [ { "id": "TSSC4_DANRE", "url": "https://www.uniprot.org/uniprot/Q0P4A6", "type": "external" } ], "mass": 34139.0, "length": 306, "protein_name": "U5 small nuclear ribonucleoprotein TSSC4", "gene_name": "tssc4", "organism": "Zebrafish", "refseq_name": "U5 small nuclear ribonucleoprotein TSSC4", "refseq_ac": [ { "id": "NP_001039313", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039313", "type": "external" } ], "gene_names_uniprotkb": "tssc4; zgc:153225", "gene_names_refseq": "tssc4; zgc:153225", "protein_names_uniprotkb": "U5 small nuclear ribonucleoprotein TSSC4", "protein_names_refseq": "U5 small nuclear ribonucleoprotein TSSC4; protein TSSC4; tumor-suppressing subchromosomal transferable fragment 4", "tax_id": 7955, "disease": "", "pathway": " (dre:559769)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC122196.1, DN766399.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898400, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC122196.1. On or before Sep 6, 2006 this sequence version replaced XP_686040.1, XP_708241.1, XP_708242.1., [RefSeq]; Protein associated with the U5 snRNP, during its maturation and its post-splicing recycling and which is required for spliceosomal tri-snRNP complex assembly in the nucleus. Has a molecular sequestering activity and transiently hinders SNRNP200 binding sites for constitutive splicing factors that intervene later during the assembly of the spliceosome and splicing. Together with its molecular sequestering activity, may also function as a molecular adapter and placeholder, coordinating the assembly of the U5 snRNP and its association with the U4/U6 di-snRNP., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0140313 molecular sequestering activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005681 spliceosomal complex;GO:0005682 U5 snRNP", "go_biological_process": "GO:0000244 spliceosomal tri-snRNP complex assembly;GO:0000387 spliceosomal snRNP assembly;GO:0006397 mRNA processing;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0P4A6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1Q8I4-1", "uniprot_id": [ { "id": "F1Q8I4_DANRE", "url": "https://www.uniprot.org/uniprot/F1Q8I4", "type": "external" } ], "mass": 45323.0, "length": 392, "protein_name": "Tyrosine-protein phosphatase non-receptor type", "gene_name": "ptpn2a", "organism": "Zebrafish", "refseq_name": "tyrosine-protein phosphatase non-receptor type 2a", "refseq_ac": [ { "id": "NP_956760", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956760", "type": "external" } ], "gene_names_uniprotkb": "ptpn2a; PTP-1B; hm:zeh1546; ptpn2; zgc:63623", "gene_names_refseq": "PTP-1B; hm:zeh1546; ptpn2a; ptpn2; zgc:63623", "protein_names_uniprotkb": "Tyrosine-protein phosphatase non-receptor type; 3.1.3.48", "protein_names_refseq": "protein tyrosine phosphatase 1B; protein tyrosine phosphatase, non-receptor type 2, a; tyrosine-protein phosphatase non-receptor type 2a", "tax_id": 7955, "disease": "pre-eclampsia (Disease Ontology:DOID:10591)", "pathway": " (dre:393438)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11116087;20838449;23974070;24122719;26469318;28814789", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01031788.1, BC055169.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Jun 25, 2025 this sequence version replaced NP_956760.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PCX4", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" } ], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0004726 non-membrane spanning protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0070373 negative regulation of ERK1 and ERK2 cascade;GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F1Q8I4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1Q8J8-1", "uniprot_id": [ { "id": "F1Q8J8_DANRE", "url": "https://www.uniprot.org/uniprot/F1Q8J8", "type": "external" } ], "mass": 73419.0, "length": 634, "protein_name": "PR domain zinc finger protein 5", "gene_name": "prdm5", "organism": "Zebrafish", "refseq_name": "PR domain zinc finger protein 5", "refseq_ac": [ { "id": "NP_001002301", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002301", "type": "external" } ], "gene_names_uniprotkb": "prdm5", "gene_names_refseq": "prdm5", "protein_names_uniprotkb": "PR domain zinc finger protein 5; PR domain-containing protein 5", "protein_names_refseq": "PR domain zinc finger protein 5; un-named hi61; unm hi61", "tax_id": 7955, "disease": "brittle cornea syndrome 2 (Disease Ontology:DOID:0080729)", "pathway": "", "pathway_count": 0, "publication_count": 10, "publication_id_list": "15256591;18231586;19169355;23109401;24240475;26469318;28871129;30458291;32106888;34330825", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AY648710.1, BC163494.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Nov 5, 2015 this sequence version replaced NP_001002301.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; PRDM5 regulates the expression of components of both canonical and non canonical wnt pathways and negatively modulates wnt signaling in vivo, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N0B1;A0AC58IJD3;A0AC58IJD4;A0AC58IJD5", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0008168 methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0006325 chromatin organization;GO:0048701 embryonic cranial skeleton morphogenesis", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1Q8J8-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1Q8W8-1", "uniprot_id": [ { "id": "F1Q8W8_DANRE", "url": "https://www.uniprot.org/uniprot/F1Q8W8", "type": "external" } ], "mass": 48640.0, "length": 417, "protein_name": "Calreticulin", "gene_name": "calr", "organism": "Zebrafish", "refseq_name": "calreticulin precursor", "refseq_ac": [ { "id": "NP_956007", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956007", "type": "external" } ], "gene_names_uniprotkb": "calr; calrl2; fc66d10; wu:fc66d10; wu:fj50c03; zgc:66153", "gene_names_refseq": "calrl2; calr; fc66d10; wu:fc66d10; wu:fj50c03; zgc:66153", "protein_names_uniprotkb": "Calreticulin", "protein_names_refseq": "calreticulin precursor; calreticulin, like 2", "tax_id": 7955, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); stomach cancer (Disease Ontology:DOID:10534); lung cancer (Disease Ontology:DOID:1324); colon carcinoma (Disease Ontology:DOID:1520); neuroendocrine tumor (Disease Ontology:DOID:169); colon cancer (Disease Ontology:DOID:219); essential thrombocythemia (Disease Ontology:DOID:2224); thrombocytosis (Disease Ontology:DOID:2228); ovarian cancer (Disease Ontology:DOID:2394); gallbladder cancer (Disease Ontology:DOID:3121); pancreatic ductal adenocarcinoma (Disease Ontology:DOID:3498); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); myelofibrosis (Disease Ontology:DOID:4971); congestive heart failure (Disease Ontology:DOID:6000); hepatocellular carcinoma (Disease Ontology:DOID:684); Burkitt lymphoma (Disease Ontology:DOID:8584); sideroblastic anemia (Disease Ontology:DOID:8955); acute myeloid leukemia (Disease Ontology:DOID:9119); colorectal cancer (Disease Ontology:DOID:9256); nasopharynx carcinoma (Disease Ontology:DOID:9261)", "pathway": " (dre:325317); (R-DRE-3000480); (R-DRE-901042); (R-DRE-983170)", "pathway_count": 4, "publication_count": 10, "publication_id_list": "16109975;19850031;23593122;24392132;25603810;35829917;36137040;36283702;36670152;38542412", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01002922.1, SRR26395063.911552.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505372, SAMEA3505374 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On or before Dec 10, 2025 this sequence version replaced NP_001431213.1, NP_956007.2. Sequence Note:. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 23, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PFS2", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0005509 calcium ion binding;GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0005829 cytosol;GO:0009986 cell surface;GO:0005789 endoplasmic reticulum membrane;GO:0033018 sarcoplasmic reticulum lumen;GO:0060473 cortical granule", "go_biological_process": "GO:0006457 protein folding;GO:0036503 ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1Q8W8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1Q8X9-1", "uniprot_id": [ { "id": "F1Q8X9_DANRE", "url": "https://www.uniprot.org/uniprot/F1Q8X9", "type": "external" } ], "mass": 91527.0, "length": 830, "protein_name": "Prominin-2 isoform X1", "gene_name": "prom2", "organism": "Zebrafish", "refseq_name": "prominin-2 isoform X1", "refseq_ac": [ { "id": "XP_009305684", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009305684", "type": "external" } ], "gene_names_uniprotkb": "prom2; fd36c02; fo25d03; prom3; prominin-3; proml3; wu:fd36c02", "gene_names_refseq": "fd36c02; fo25d03; prom2; prom3; prominin-3; proml3; wu:fd36c02", "protein_names_uniprotkb": "Prominin-2 isoform X1", "protein_names_refseq": "prominin-2 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:556596)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B855", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005929 cilium;GO:0016324 apical plasma membrane;GO:0005902 microvillus;GO:0031528 microvillus membrane;GO:0071914 prominosome", "go_biological_process": "GO:0007507 heart development;GO:0032528 microvillus organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1Q8X9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1Q929-1", "uniprot_id": [ { "id": "F1Q929_DANRE", "url": "https://www.uniprot.org/uniprot/F1Q929", "type": "external" } ], "mass": 74698.0, "length": 667, "protein_name": "Potassium voltage-gated channel subfamily A member 4", "gene_name": "kcna4", "organism": "Zebrafish", "refseq_name": "potassium voltage-gated channel subfamily A member 4", "refseq_ac": [ { "id": "XP_005169005", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169005", "type": "external" } ], "gene_names_uniprotkb": "kcna4", "gene_names_refseq": "kcna4", "protein_names_uniprotkb": "Potassium voltage-gated channel subfamily A member 4; Voltage-gated potassium channel subunit Kv1.4", "protein_names_refseq": "potassium voltage-gated channel subfamily A member 4", "tax_id": 7955, "disease": "episodic ataxia type 1 (Disease Ontology:DOID:0050989); epilepsy (Disease Ontology:DOID:1826)", "pathway": " (dre:559036)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9PPU3", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.2", "type": "external" } ], "go_molecular_function": "GO:0005251 delayed rectifier potassium channel activity;GO:0030955 potassium ion binding", "go_cellular_component": "GO:0016020 membrane;GO:0030424 axon;GO:0043197 dendritic spine;GO:0008076 voltage-gated potassium channel complex", "go_biological_process": "GO:0051260 protein homooligomerization;GO:0001508 action potential;GO:0071805 potassium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1Q929-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1Q9F5-1", "uniprot_id": [ { "id": "F1Q9F5_DANRE", "url": "https://www.uniprot.org/uniprot/F1Q9F5", "type": "external" } ], "mass": 107073.0, "length": 953, "protein_name": "Importin-13", "gene_name": "ipo13b", "organism": "Zebrafish", "refseq_name": "importin-13 isoform X1", "refseq_ac": [ { "id": "XP_002665826", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002665826", "type": "external" } ], "gene_names_uniprotkb": "ipo13b", "gene_names_refseq": "ipo13b", "protein_names_uniprotkb": "Importin-13", "protein_names_refseq": "importin-13 isoform X1", "tax_id": 7955, "disease": "microphthalmia (Disease Ontology:DOID:10629); cataract (Disease Ontology:DOID:83)", "pathway": " (dre:100319138)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_002665826.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RHX2", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0010842 retina layer formation;GO:0007632 visual behavior;GO:0006606 protein import into nucleus;GO:0007634 optokinetic behavior", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1Q9F5-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1Q9W8-1", "uniprot_id": [ { "id": "F1Q9W8_DANRE", "url": "https://www.uniprot.org/uniprot/F1Q9W8", "type": "external" } ], "mass": 23257.0, "length": 210, "protein_name": "Ras-related protein Rab-25", "gene_name": "rab25b", "organism": "Zebrafish", "refseq_name": "ras-related protein Rab-25b isoform X1", "refseq_ac": [ { "id": "XP_017206847", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206847", "type": "external" } ], "gene_names_uniprotkb": "rab25b; zgc:112037", "gene_names_refseq": "rab25b; zgc:112037", "protein_names_uniprotkb": "Ras-related protein Rab-25", "protein_names_refseq": "ras-related protein Rab-25b isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:574424); (R-DRE-8873719)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB25 regulates epithelial cell differentiation, proliferation and survival, thereby playing key roles in tumorigenesis. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions. May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z147", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0031260 pseudopodium membrane;GO:0005794 Golgi apparatus;GO:0055037 recycling endosome", "go_biological_process": "GO:0030866 cortical actin cytoskeleton organization;GO:0006887 exocytosis;GO:0032465 regulation of cytokinesis;GO:2001135 regulation of endocytic recycling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1Q9W8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1Q9X6-1", "uniprot_id": [ { "id": "F1Q9X6_DANRE", "url": "https://www.uniprot.org/uniprot/F1Q9X6", "type": "external" } ], "mass": 36982.0, "length": 328, "protein_name": "Melanocortin receptor 5", "gene_name": "mc5rb", "organism": "Zebrafish", "refseq_name": "melanocortin 5b receptor isoform X1", "refseq_ac": [ { "id": "XP_005158226", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005158226", "type": "external" } ], "gene_names_uniprotkb": "mc5rb; mc5br; mc5ra; zMC5b; zgc:194217", "gene_names_refseq": "mc5br; mc5ra; mc5rb; zMC5b; zgc:194217", "protein_names_uniprotkb": "Melanocortin receptor 5", "protein_names_refseq": "melanocortin 5b receptor isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:286835)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12851332;17341684;17603878;17707598;19225141;26169937;30288633;31178320;36290123", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B532", "ec_number_list": [], "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0004977 melanocortin receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "F1Q9X6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QA15-1", "uniprot_id": [ { "id": "F1QA15_DANRE", "url": "https://www.uniprot.org/uniprot/F1QA15", "type": "external" } ], "mass": 103012.0, "length": 906, "protein_name": "Gamma-tubulin complex component 3 isoform X1", "gene_name": "tubgcp3", "organism": "Zebrafish", "refseq_name": "gamma-tubulin complex component 3 isoform X1", "refseq_ac": [ { "id": "XP_005171052", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171052", "type": "external" } ], "gene_names_uniprotkb": "tubgcp3; GCP3; SPC98P; si:dz75p05.1; wu:fc09h08", "gene_names_refseq": "GCP3; SPC98P; si:dz75p05.1; tubgcp3; wu:fc09h08", "protein_names_uniprotkb": "Gamma-tubulin complex component 3 isoform X1", "protein_names_refseq": "gamma-tubulin complex component 3 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:563517); (R-DRE-380320)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "15520368;16408288;17293149;18335061;22046393;27189481;28252024;31178691;32344036;9566968", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BI75", "ec_number_list": [], "go_molecular_function": "GO:0043015 gamma-tubulin binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005813 centrosome;GO:0005874 microtubule;GO:0000930 gamma-tubulin complex", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0003407 neural retina development;GO:0007020 microtubule nucleation;GO:0051225 spindle assembly;GO:0051321 meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QA15-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QAA7-1", "uniprot_id": [ { "id": "F1QAA7_DANRE", "url": "https://www.uniprot.org/uniprot/F1QAA7", "type": "external" } ], "mass": 78599.0, "length": 698, "protein_name": "Propionate--CoA ligase", "gene_name": "acss2", "organism": "Zebrafish", "refseq_name": "acetyl-coenzyme A synthetase, cytoplasmic", "refseq_ac": [ { "id": "NP_001315282", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315282", "type": "external" } ], "gene_names_uniprotkb": "acss2; fa04c03; fj80b06; fj80h04; wu:fa04c03; wu:fj80b06; wu:fj80h04; zgc:92200", "gene_names_refseq": "acss2; fa04c03; fj80b06; fj80h04; wu:fa04c03; wu:fj80b06; wu:fj80h04; zgc:92200", "protein_names_uniprotkb": "Propionate--CoA ligase; 6.2.1.17; 6.2.1.1", "protein_names_refseq": "acetyl-coenzyme A synthetase, cytoplasmic", "tax_id": 7955, "disease": "orofacial cleft (Disease Ontology:DOID:0050567); morbid obesity (Disease Ontology:DOID:11981); lymphangioleiomyomatosis (Disease Ontology:DOID:3319)", "pathway": " (dre:436914); (R-DRE-2151201); (R-DRE-71384)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "15520368;16109975;17762044;30970187;32459962;35151729", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395064.1395477.1, SRR26395017.645408.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Jun 12, 2016 this sequence version replaced XP_005162008.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P9T3", "ec_number_list": [ { "id": "6.2.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.1", "type": "external" }, { "id": "6.2.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.17", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0003987 acetate-CoA ligase activity;GO:0050218 propionate-CoA ligase activity;GO:0016208 AMP binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0006085 acetyl-CoA biosynthetic process;GO:0019427 acetyl-CoA biosynthetic process from acetate", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F1QAA7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QAD7-1", "uniprot_id": [ { "id": "F1QAD7_DANRE", "url": "https://www.uniprot.org/uniprot/F1QAD7", "type": "external" } ], "mass": 124445.0, "length": 1069, "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "pik3ca", "organism": "Zebrafish", "refseq_name": "phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "refseq_ac": [ { "id": "XP_009304452", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304452", "type": "external" } ], "gene_names_uniprotkb": "pik3ca", "gene_names_refseq": "pik3ca", "protein_names_uniprotkb": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; 2.7.1.137; 2.7.1.153; 2.7.11.1; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; Phosphoinositide-3-kinase catalytic alpha polypeptide; Serine/threonine protein kinase PIK3CA", "protein_names_refseq": "phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "tax_id": 7955, "disease": "estrogen-receptor positive breast cancer (Disease Ontology:DOID:0060075); cerebral cavernous malformation (Disease Ontology:DOID:0060669); colorectal carcinoma (Disease Ontology:DOID:0080199); CLOVES syndrome (Disease Ontology:DOID:0080351); Cowden syndrome 5 (Disease Ontology:DOID:0081001); autosomal recessive polycystic kidney disease (Disease Ontology:DOID:0110861); epidermal nevus (Disease Ontology:DOID:0111162); stomach cancer (Disease Ontology:DOID:10534); lung cancer (Disease Ontology:DOID:1324); breast cancer (Disease Ontology:DOID:1612); rectal benign neoplasm (Disease Ontology:DOID:1984); colon adenocarcinoma (Disease Ontology:DOID:234); ovarian cancer (Disease Ontology:DOID:2394); cutaneous Paget's disease (Disease Ontology:DOID:3450); breast angiosarcoma (Disease Ontology:DOID:4511); esophageal cancer (Disease Ontology:DOID:5041); seborrheic keratosis (Disease Ontology:DOID:6498); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dre:561737); (R-DRE-109704); (R-DRE-112399); (R-DRE-114604); (R-DRE-1250342); (R-DRE-1257604); (R-DRE-1433557); (R-DRE-1660499); (R-DRE-180292); (R-DRE-186763); (R-DRE-1963642); (R-DRE-198203); (R-DRE-201556); (R-DRE-210993); (R-DRE-389357); (R-DRE-416476); (R-DRE-4420097); (R-DRE-5654689); (R-DRE-5654695); (R-DRE-5654710); (R-DRE-5654720); (R-DRE-5673001); (R-DRE-6811558); (R-DRE-8851907); (R-DRE-8853659); (R-DRE-9009391); (R-DRE-9013149); (R-DRE-9013404); (R-DRE-9027276); (R-DRE-912631); (R-DRE-9607240); (R-DRE-9842663)", "pathway_count": 32, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 19, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3BDU2;A0AC58GTH7;A0AC58GTI7;A0AC58GTI9;A0AC58GTK5", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0016303 1-phosphatidylinositol-3-kinase activity;GO:0046934 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity;GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005944 phosphatidylinositol 3-kinase complex, class IB;GO:0005943 phosphatidylinositol 3-kinase complex, class IA", "go_biological_process": "GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process;GO:0001525 angiogenesis;GO:0016477 cell migration;GO:0006909 phagocytosis;GO:0048015 phosphatidylinositol-mediated signaling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QAD7-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QAJ4-1", "uniprot_id": [ { "id": "GATA_DANRE", "url": "https://www.uniprot.org/uniprot/F1QAJ4", "type": "external" } ], "mass": 58920.0, "length": 536, "protein_name": "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "gene_name": "qrsl1", "organism": "Zebrafish", "refseq_name": "glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "refseq_ac": [ { "id": "NP_001112370", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001112370", "type": "external" } ], "gene_names_uniprotkb": "qrsl1; QRSL1; wu:fi03b10", "gene_names_refseq": "qrsl1; wu:fi03b10", "protein_names_uniprotkb": "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; 6.3.5.7; Glu-AdT subunit A; Glutaminyl-tRNA synthase-like protein 1", "protein_names_refseq": "QRSL1, glutaminyl-tRNA amidotransferase subunit A; glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1; glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "tax_id": 7955, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); combined oxidative phosphorylation deficiency 40 (Disease Ontology:DOID:0112117)", "pathway": " (dre:327329)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01031976.1, BC044563.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000017.1. On Mar 7, 2008 this sequence version replaced XP_695120.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q803A5", "ec_number_list": [ { "id": "6.3.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.5.-", "type": "external" }, { "id": "6.3.5.7", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.5.7", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex", "go_biological_process": "GO:0032543 mitochondrial translation;GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1QAJ4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QAX5-1", "uniprot_id": [ { "id": "F1QAX5_DANRE", "url": "https://www.uniprot.org/uniprot/F1QAX5", "type": "external" } ], "mass": 68012.0, "length": 608, "protein_name": "Zinc finger-containing ubiquitin peptidase 1", "gene_name": "zufsp", "organism": "Zebrafish", "refseq_name": "zinc finger-containing ubiquitin peptidase 1", "refseq_ac": [ { "id": "NP_001076474", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076474", "type": "external" } ], "gene_names_uniprotkb": "zufsp; im:7145879; zgc:158611", "gene_names_refseq": "im:7145879; zgc:158611; zufsp; zup1", "protein_names_uniprotkb": "Zinc finger-containing ubiquitin peptidase 1; 3.4.19.12; Lys-63-specific deubiquitinase ZUFSP; Zinc finger with UFM1-specific peptidase domain protein", "protein_names_refseq": "zinc finger with UFM1-specific peptidase domain; zinc finger-containing ubiquitin peptidase 1", "tax_id": 7955, "disease": "", "pathway": " (dre:562478)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "26469318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC133133.1, GDQQ01031603.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898400, SAMEA898401 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Oct 31, 2009 this sequence version replaced NP_001076474.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Deubiquitinase with endodeubiquitinase activity that specifically interacts with and cleaves 'Lys-63'-linked long polyubiquitin chains. Shows only weak activity against 'Lys-11' and 'Lys-48'-linked chains. Plays an important role in genome stability pathways, functioning to prevent spontaneous DNA damage and also promote cellular survival in response to exogenous DNA damage. Modulates the ubiquitination status of replication protein A (RPA) complex proteins in response to replication stress., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NC71", "ec_number_list": [], "go_molecular_function": "GO:0071567 deUFMylase activity;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1QAX5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QB78-1", "uniprot_id": [ { "id": "F1QB78_DANRE", "url": "https://www.uniprot.org/uniprot/F1QB78", "type": "external" } ], "mass": 64699.0, "length": 578, "protein_name": "Plasminogen activator", "gene_name": "plat", "organism": "Zebrafish", "refseq_name": "tissue-type plasminogen activator", "refseq_ac": [ { "id": "XP_002663097", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002663097", "type": "external" } ], "gene_names_uniprotkb": "plat", "gene_names_refseq": "plat", "protein_names_uniprotkb": "Plasminogen activator; 3.4.21.68", "protein_names_refseq": "tissue-type plasminogen activator", "tax_id": 7955, "disease": "stroke (Disease Ontology:DOID:0051061); acute promyelocytic leukemia (Disease Ontology:DOID:0060318); von Willebrand's disease 1 (Disease Ontology:DOID:0060573); osteonecrosis (Disease Ontology:DOID:10159); IgA vasculitis (Disease Ontology:DOID:11123); disseminated intravascular coagulation (Disease Ontology:DOID:11247); diabetic angiopathy (Disease Ontology:DOID:11713); gestational diabetes (Disease Ontology:DOID:11714); factor VIII deficiency (Disease Ontology:DOID:12134); blood coagulation disease (Disease Ontology:DOID:1247); hemolytic-uremic syndrome (Disease Ontology:DOID:12554); severe acute respiratory syndrome (Disease Ontology:DOID:2945); antiphospholipid syndrome (Disease Ontology:DOID:2988); acute kidney failure (Disease Ontology:DOID:3021); Noonan syndrome (Disease Ontology:DOID:3490); pancreatic adenocarcinoma (Disease Ontology:DOID:4074); myocardial infarction (Disease Ontology:DOID:5844); leukopenia (Disease Ontology:DOID:615); peritonitis (Disease Ontology:DOID:8283); autoimmune thrombocytopenic purpura (Disease Ontology:DOID:8924); type 2 diabetes mellitus (Disease Ontology:DOID:9352); diabetic neuropathy (Disease Ontology:DOID:9743); type 1 diabetes mellitus (Disease Ontology:DOID:9744); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:100320028); (R-DRE-186797); (R-DRE-75205)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 24, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RLZ3", "ec_number_list": [ { "id": "3.4.21.7", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.7", "type": "external" }, { "id": "3.4.21.68", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.68", "type": "external" } ], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0014909 smooth muscle cell migration;GO:0031639 plasminogen activation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QB78-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QB90-1", "uniprot_id": [ { "id": "F1QB90_DANRE", "url": "https://www.uniprot.org/uniprot/F1QB90", "type": "external" } ], "mass": 26088.0, "length": 231, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "tp53rk", "organism": "Zebrafish", "refseq_name": "EKC/KEOPS complex subunit TP53RK", "refseq_ac": [ { "id": "NP_001018386", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018386", "type": "external" } ], "gene_names_uniprotkb": "tp53rk; fd05d02; wu:fd05d02; zgc:110000", "gene_names_refseq": "fd05d02; tp53rk; wu:fd05d02; zgc:110000", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1; Nori-2; TP53-regulating kinase; p53-related protein kinase", "protein_names_refseq": "EKC/KEOPS complex subunit TP53RK", "tax_id": 7955, "disease": "Galloway-Mowat syndrome 4 (Disease Ontology:DOID:0080246)", "pathway": " (dre:553571); (R-DRE-6804756)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "21553381;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01041713.1, SRR26395013.1225887.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1 and EH547402.1. On or before Feb 17, 2016 this sequence version replaced XP_005172833.1, NP_001018386.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP. Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N5U6", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0000408 EKC/KEOPS complex", "go_biological_process": "GO:0008033 tRNA processing;GO:0070525 tRNA threonylcarbamoyladenosine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1QB90-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QMZ5-1", "uniprot_id": [ { "id": "F1QMZ5_DANRE", "url": "https://www.uniprot.org/uniprot/F1QMZ5", "type": "external" } ], "mass": 131510.0, "length": 1190, "protein_name": "Zinc finger E-box-binding homeobox 1 isoform X1", "gene_name": "zeb1a", "organism": "Zebrafish", "refseq_name": "zinc finger E-box-binding homeobox 1 isoform X1", "refseq_ac": [ { "id": "XP_001344107", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001344107", "type": "external" } ], "gene_names_uniprotkb": "zeb1a", "gene_names_refseq": "zeb1a", "protein_names_uniprotkb": "Zinc finger E-box-binding homeobox 1 isoform X1", "protein_names_refseq": "zinc finger E-box-binding homeobox 1 isoform X1", "tax_id": 7955, "disease": "posterior polymorphous corneal dystrophy 3 (Disease Ontology:DOID:0110857); Fuchs' endothelial dystrophy (Disease Ontology:DOID:11555); HTLV-1-associated myelopathy/tropical spastic paraparesis (Disease Ontology:DOID:321)", "pathway": " (dre:100004929)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001344107.3. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PZR7", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0010470 regulation of gastrulation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0048745 smooth muscle tissue development;GO:0070587 regulation of cell-cell adhesion involved in gastrulation;GO:0090130 tissue migration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QMZ5-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QBE2-1", "uniprot_id": [ { "id": "F1QBE2_DANRE", "url": "https://www.uniprot.org/uniprot/F1QBE2", "type": "external" } ], "mass": 36442.0, "length": 317, "protein_name": "Deoxyribonuclease", "gene_name": "dnase1l1", "organism": "Zebrafish", "refseq_name": "deoxyribonuclease-1-like 1 precursor", "refseq_ac": [ { "id": "NP_998318", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998318", "type": "external" } ], "gene_names_uniprotkb": "dnase1l1; dnase1l3; wu:fb44e02; zgc:66031", "gene_names_refseq": "dnase1l1; dnase1l3; wu:fb44e02; zgc:66031", "protein_names_uniprotkb": "Deoxyribonuclease", "protein_names_refseq": "deoxyribonuclease I-like 3; deoxyribonuclease-1-like 1 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:792196); (R-DRE-6798695)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "23922899;27189481;32061775", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC056304.1, SRR26395064.383704.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505375 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CN022406.1, BC056304.1, EH526021.1 and JBMGRA010000023.1. On or before Mar 27, 2009 this sequence version replaced XP_001331728.1, NP_998318.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PNY3", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0004530 deoxyribonuclease I activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006308 DNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1QBE2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QBE9-1", "uniprot_id": [ { "id": "F1QBE9_DANRE", "url": "https://www.uniprot.org/uniprot/F1QBE9", "type": "external" } ], "mass": 12213.0, "length": 106, "protein_name": "C-C motif chemokine 25", "gene_name": "ccl25b", "organism": "Zebrafish", "refseq_name": "C-C motif chemokine 25b precursor", "refseq_ac": [ { "id": "NP_001186964", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186964", "type": "external" } ], "gene_names_uniprotkb": "ccl25b", "gene_names_refseq": "ccl25b", "protein_names_uniprotkb": "C-C motif chemokine 25; Small-inducible cytokine A25", "protein_names_refseq": "C-C motif chemokine 25b precursor; CCL-chr11a; Dr11_WGA839_1_159228; ccl21; chemokine CCL-C11a", "tax_id": 7955, "disease": "", "pathway": " (dre:795788); (R-DRE-380108); (R-DRE-416476); (R-DRE-418594); (R-DRE-444473)", "pathway_count": 5, "publication_count": 10, "publication_id_list": "16365434;16697551;18482437;19559469;22342843;33785593;35111746;35264012;35652354;36543127", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NXL4", "ec_number_list": [], "go_molecular_function": "GO:0008009 chemokine activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006954 inflammatory response;GO:0006955 immune response;GO:1902033 regulation of hematopoietic stem cell proliferation;GO:0097535 lymphoid lineage cell migration into thymus;GO:2000471 regulation of hematopoietic stem cell migration", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QBE9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QBS1-1", "uniprot_id": [ { "id": "F1QBS1_DANRE", "url": "https://www.uniprot.org/uniprot/F1QBS1", "type": "external" } ], "mass": 74669.0, "length": 671, "protein_name": "RNA helicase", "gene_name": "ddx17", "organism": "Zebrafish", "refseq_name": "probable ATP-dependent RNA helicase DDX17", "refseq_ac": [ { "id": "NP_001313320", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313320", "type": "external" } ], "gene_names_uniprotkb": "ddx17; hm:zeh0176; si:dkey-156n14.5; zeh0176", "gene_names_refseq": "ddx17; hm:zeh0176; si:dkey-156n14.5; zeh0176", "protein_names_uniprotkb": "RNA helicase; 3.6.4.13", "protein_names_refseq": "DEAD box polypeptide 17; probable ATP-dependent RNA helicase DDX17", "tax_id": 7955, "disease": "", "pathway": " (dre:556764); (R-DRE-3899300)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "11116087;28252024", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395039.1833710.1, SRR26395028.1182038.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On Jun 12, 2025 this sequence version replaced NP_001313320.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P2L5", "ec_number_list": [ { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0000380 alternative mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1QBS1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QBS8-1", "uniprot_id": [ { "id": "F1QBS8_DANRE", "url": "https://www.uniprot.org/uniprot/F1QBS8", "type": "external" } ], "mass": 333206.0, "length": 3006, "protein_name": "Cadherin EGF LAG seven-pass G-type receptor 1", "gene_name": "celsr1b", "organism": "Zebrafish", "refseq_name": "cadherin EGF LAG seven-pass G-type receptor 1", "refseq_ac": [ { "id": "XP_001920772", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001920772", "type": "external" } ], "gene_names_uniprotkb": "celsr1b", "gene_names_refseq": "celsr1b", "protein_names_uniprotkb": "Cadherin EGF LAG seven-pass G-type receptor 1", "protein_names_refseq": "cadherin EGF LAG seven-pass G-type receptor 1", "tax_id": 7955, "disease": "yellow nail syndrome (Disease Ontology:DOID:0050468); hereditary lymphedema (Disease Ontology:DOID:0050580)", "pathway": " (dre:556520)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_001920772.1. COMPLETENESS: full length., [RefSeq]; Receptor that may have an important role in cell/cell signaling during nervous system formation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QQS8", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005912 adherens junction", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007409 axonogenesis;GO:0007507 heart development;GO:0021915 neural tube development;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QBS8-1", "record_type": "protein", "filter_code": "0000000.0000011.001000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QBZ9-1", "uniprot_id": [ { "id": "F1QBZ9_DANRE", "url": "https://www.uniprot.org/uniprot/F1QBZ9", "type": "external" } ], "mass": 314108.0, "length": 2870, "protein_name": "Multiple epidermal growth factor-like domains protein 8", "gene_name": "megf8", "organism": "Zebrafish", "refseq_name": "multiple epidermal growth factor-like domains protein 8", "refseq_ac": [ { "id": "XP_005158088", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005158088", "type": "external" } ], "gene_names_uniprotkb": "megf8", "gene_names_refseq": "megf8", "protein_names_uniprotkb": "Multiple epidermal growth factor-like domains protein 8", "protein_names_refseq": "multiple epidermal growth factor-like domains protein 8", "tax_id": 7955, "disease": "visceral heterotaxy (Disease Ontology:DOID:0050545); Carpenter syndrome (Disease Ontology:DOID:0060234); Carpenter syndrome 2 (Disease Ontology:DOID:0061099)", "pathway": " (dre:791154)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B4Z5", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0060972 left/right pattern formation;GO:0048731 system development;GO:0007368 determination of left/right symmetry;GO:0042074 cell migration involved in gastrulation;GO:0048513 animal organ development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QBZ9-1", "record_type": "protein", "filter_code": "0000000.0000011.001000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QC01-1", "uniprot_id": [ { "id": "F1QC01_DANRE", "url": "https://www.uniprot.org/uniprot/F1QC01", "type": "external" } ], "mass": 50444.0, "length": 448, "protein_name": "Kinase", "gene_name": "itpka", "organism": "Zebrafish", "refseq_name": "inositol-trisphosphate 3-kinase A", "refseq_ac": [ { "id": "NP_001313405", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313405", "type": "external" } ], "gene_names_uniprotkb": "itpka; IP3K; kinase; sb:eu722; si:busm1-107o16.2; si:busm1-181p14.3; si:dz107o16.2; si:dz181p14.3; si:dz265n10.1", "gene_names_refseq": "IP3K; itpka; kinase; sb:eu722; si:busm1-107o16.2; si:busm1-181p14.3; si:dz107o16.2; si:dz181p14.3; si:dz265n10.1", "protein_names_uniprotkb": "Kinase; 2.7.-.-", "protein_names_refseq": "1D-myo-inositol-trisphosphate 3-kinase A; inositol 1,4,5-triphosphate 3-kinase; inositol 1,4,5-trisphosphate 3-kinase A; inositol-trisphosphate 3-kinase A", "tax_id": 7955, "disease": "", "pathway": " (dre:368717)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "21873635", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01023745.1, GDQH01004931.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505375, SAMEA3505378 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000017.1. On Jun 25, 2025 this sequence version replaced NP_001313405.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3D6", "ec_number_list": [ { "id": "2.7.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.-.-", "type": "external" } ], "go_molecular_function": "GO:0000828 inositol hexakisphosphate kinase activity;GO:0005524 ATP binding;GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0046854 phosphatidylinositol phosphate biosynthetic process;GO:0032958 inositol phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1QC01-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QC10-1", "uniprot_id": [ { "id": "F1QC10_DANRE", "url": "https://www.uniprot.org/uniprot/F1QC10", "type": "external" } ], "mass": 43717.0, "length": 389, "protein_name": "Sphingosine 1-phosphate receptor 4", "gene_name": "s1pr4", "organism": "Zebrafish", "refseq_name": "sphingosine 1-phosphate receptor 4", "refseq_ac": [ { "id": "NP_001112363", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001112363", "type": "external" } ], "gene_names_uniprotkb": "s1pr4; edg6; im:6805837; si:ch211-35n24.1", "gene_names_refseq": "edg6; im:6805837; s1pr4; si:ch211-35n24.1", "protein_names_uniprotkb": "Sphingosine 1-phosphate receptor 4", "protein_names_refseq": "endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 6; sphingosine 1-phosphate receptor 4", "tax_id": 7955, "disease": "", "pathway": " (dre:402857); (R-DRE-418594); (R-DRE-419408)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "22855693;23229546;26094551;26254596;26469318;27399967;28658311;29922649", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC066587.1, GFIL01034324.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476734, SAMEA4476737 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000022.1. On Mar 7, 2008 this sequence version replaced XP_001334842.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N1YZH4;A0AC58IDY6", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0038036 sphingosine-1-phosphate receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0030593 neutrophil chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "F1QC10-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QC17-1", "uniprot_id": [ { "id": "EMI1A_DANRE", "url": "https://www.uniprot.org/uniprot/F1QC17", "type": "external" } ], "mass": 113410.0, "length": 1014, "protein_name": "EMILIN-1-A", "gene_name": "emilin1a", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "emilin1a; im:7159005; si:dkey-20n10.2", "gene_names_refseq": "", "protein_names_uniprotkb": "EMILIN-1-A; Elastin microfibril interfacer 1a", "protein_names_refseq": "", "tax_id": 7955, "disease": "autosomal dominant distal hereditary motor neuronopathy 10 (Disease Ontology:DOID:0081399)", "pathway": " (dre:566473); (R-DRE-114608); (R-DRE-2129379); (R-DRE-5173105)", "pathway_count": 4, "publication_count": 10, "publication_id_list": "18095348;20615881;21571218;23594743;26168398;26469318;30924555;31978608;35052463;37196825", "class_list": "", "function": "May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B7W4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0030097 hemopoiesis;GO:0140060 axon arborization", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QC17-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QCC9-1", "uniprot_id": [ { "id": "F1QCC9_DANRE", "url": "https://www.uniprot.org/uniprot/F1QCC9", "type": "external" } ], "mass": 50912.0, "length": 446, "protein_name": "Synaptotagmin Vb", "gene_name": "syt5b", "organism": "Zebrafish", "refseq_name": "synaptotagmin Vb", "refseq_ac": [ { "id": "NP_001018382", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018382", "type": "external" } ], "gene_names_uniprotkb": "syt5b; zgc:109988", "gene_names_refseq": "syt5b; zgc:109988", "protein_names_uniprotkb": "Synaptotagmin Vb", "protein_names_refseq": "synaptotagmin Vb", "tax_id": 7955, "disease": "", "pathway": " (dre:553567)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "15238157;17672888;20078875;26469318;27189481;28252024;34468021;38765140", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC095109.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC095109.1. On Jul 12, 2008 this sequence version replaced NP_001018382.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N6C4", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0005544 calcium-dependent phospholipid binding;GO:0000149 SNARE binding;GO:0061891 calcium ion sensor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0030672 synaptic vesicle membrane;GO:0070382 exocytic vesicle;GO:0042584 chromaffin granule membrane", "go_biological_process": "GO:0016192 vesicle-mediated transport;GO:0017158 regulation of calcium ion-dependent exocytosis;GO:2000300 regulation of synaptic vesicle exocytosis;GO:0099502 calcium-dependent activation of synaptic vesicle fusion", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "F1QCC9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QCG4-1", "uniprot_id": [ { "id": "F1QCG4_DANRE", "url": "https://www.uniprot.org/uniprot/F1QCG4", "type": "external" } ], "mass": 34962.0, "length": 310, "protein_name": "NF-kappa-B inhibitor alpha", "gene_name": "nfkbiaa", "organism": "Zebrafish", "refseq_name": "nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a", "refseq_ac": [ { "id": "NP_998349", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998349", "type": "external" } ], "gene_names_uniprotkb": "nfkbiaa; fj16a07; ikbaA; wu:fj16a07; zgc:85769", "gene_names_refseq": "fj16a07; ikbaA; nfkbiaa; wu:fj16a07; zgc:85769", "protein_names_uniprotkb": "NF-kappa-B inhibitor alpha; I-kappa-B-alpha", "protein_names_refseq": "NF-kappaB inhibitor alpha-like protein A; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a", "tax_id": 7955, "disease": "childhood-onset asthma (Disease Ontology:DOID:0080815); ectodermal dysplasia and immunodeficiency 2 (Disease Ontology:DOID:0081079); prostate cancer (Disease Ontology:DOID:10283); bronchopulmonary dysplasia (Disease Ontology:DOID:11650); nephrotic syndrome (Disease Ontology:DOID:1184); Sjogren's syndrome (Disease Ontology:DOID:12894); lung cancer (Disease Ontology:DOID:1324); diarrhea (Disease Ontology:DOID:13250); hepatitis C (Disease Ontology:DOID:1883); melanoma (Disease Ontology:DOID:1909); hepatitis B (Disease Ontology:DOID:2043); prostate adenocarcinoma (Disease Ontology:DOID:2526); pulmonary tuberculosis (Disease Ontology:DOID:2957); glioblastoma (Disease Ontology:DOID:3068); atopic dermatitis (Disease Ontology:DOID:3310); pneumonia (Disease Ontology:DOID:552); hepatocellular carcinoma (Disease Ontology:DOID:684); Hodgkin's lymphoma (Disease Ontology:DOID:8567); multiple myeloma (Disease Ontology:DOID:9538); toxoplasmosis (Disease Ontology:DOID:9965)", "pathway": " (dre:406463)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "15169890;16051172;16109975;17371995;19779068;38270285;39059593;39141879;39178124;39242546", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC068382.1, GDQH01002945.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1, EH437254.1 and EH466098.1. On Aug 25, 2015 this sequence version replaced NP_998349.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL (RELA/p65 and NFKB1/p50) dimers in the cytoplasm by masking their nuclear localization signals. On cellular stimulation by immune and pro-inflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 20, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N1Z434", "ec_number_list": [], "go_molecular_function": "GO:0051059 NF-kappaB binding;GO:0140311 protein sequestering activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:1901532 regulation of hematopoietic progenitor cell differentiation;GO:0009615 response to virus;GO:0043124 negative regulation of canonical NF-kappaB signal transduction;GO:0071345 cellular response to cytokine stimulus;GO:1901533 negative regulation of hematopoietic progenitor cell differentiation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QCG4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QCP4-1", "uniprot_id": [ { "id": "F1QCP4_DANRE", "url": "https://www.uniprot.org/uniprot/F1QCP4", "type": "external" } ], "mass": 66807.0, "length": 592, "protein_name": "Cyclic GMP-AMP synthase", "gene_name": "cgasa", "organism": "Zebrafish", "refseq_name": "cyclic GMP-AMP synthase", "refseq_ac": [ { "id": "XP_685111", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685111", "type": "external" } ], "gene_names_uniprotkb": "cgasa", "gene_names_refseq": "cgasa", "protein_names_uniprotkb": "Cyclic GMP-AMP synthase", "protein_names_refseq": "cyclic GMP-AMP synthase", "tax_id": 7955, "disease": "", "pathway": " (dre:557043)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UUZ3", "ec_number_list": [], "go_molecular_function": "GO:0061501 2',3'-cyclic GMP-AMP synthase activity;GO:0003682 chromatin binding;GO:0003690 double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0035861 site of double-strand break", "go_biological_process": "GO:0071360 cellular response to exogenous dsRNA;GO:2000042 negative regulation of double-strand break repair via homologous recombination;GO:0045087 innate immune response;GO:0006974 DNA damage response;GO:0002230 positive regulation of defense response to virus by host", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QCP4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QCR7-1", "uniprot_id": [ { "id": "F1QCR7_DANRE", "url": "https://www.uniprot.org/uniprot/F1QCR7", "type": "external" } ], "mass": 95577.0, "length": 849, "protein_name": "Neurofilament, medium polypeptide a", "gene_name": "nefma", "organism": "Zebrafish", "refseq_name": "neurofilament, medium polypeptide a", "refseq_ac": [ { "id": "NP_001104684", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104684", "type": "external" } ], "gene_names_uniprotkb": "nefma; zgc:112359", "gene_names_refseq": "nefma; zgc:112359", "protein_names_uniprotkb": "Neurofilament, medium polypeptide a", "protein_names_refseq": "neurofilament, medium polypeptide a", "tax_id": 7955, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526)", "pathway": " (dre:553718)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "23437360;24089481;25556858;26469318;27159642;32364583;32937099;34991727;36517242;38017520", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC155734.1, GFIL01028061.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476743, SAMEA4476789 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Feb 5, 2016 this sequence version replaced NP_001104684.1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference genome strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NGQ3", "ec_number_list": [], "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton", "go_cellular_component": "GO:0030424 axon;GO:0005882 intermediate filament;GO:0099160 postsynaptic intermediate filament cytoskeleton", "go_biological_process": "GO:0033693 neurofilament bundle assembly", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QCR7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QCU4-1", "uniprot_id": [ { "id": "F1QCU4_DANRE", "url": "https://www.uniprot.org/uniprot/F1QCU4", "type": "external" } ], "mass": 54394.0, "length": 496, "protein_name": "Ectonucleoside triphosphate diphosphohydrolase 8", "gene_name": "entpd8", "organism": "Zebrafish", "refseq_name": "ectonucleoside triphosphate diphosphohydrolase 8", "refseq_ac": [ { "id": "NP_001002379", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002379", "type": "external" } ], "gene_names_uniprotkb": "entpd8; si:ch211-10e8.4; zC10E8.4; zgc:92065", "gene_names_refseq": "entpd8; si:ch211-10e8.4; zC10E8.4; zgc:92065", "protein_names_uniprotkb": "Ectonucleoside triphosphate diphosphohydrolase 8; 3.6.1.5", "protein_names_refseq": "NTPDase8; ectonucleoside triphosphate diphosphohydrolase 8", "tax_id": 7955, "disease": "", "pathway": " (dre:436652); (R-DRE-8850843)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "19922813;22438865;22995533;24002024;25533845;26469318;26769247;27189619", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01009682.1, SRR32588714.33170.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1, DT068903.1 and DR728193.1. On Nov 19, 2009 this sequence version replaced NP_001002379.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N0F4;A0AC58JQZ1;A0AC58JR04;A0AC58JR05;A0AC58JR09;A0AC58JR11;F1R0W4", "ec_number_list": [ { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.6", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.13", "type": "external" }, { "id": "3.6.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.16", "type": "external" }, { "id": "3.6.1.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.53", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004382 GDP phosphatase activity;GO:0045134 UDP phosphatase activity;GO:0017111 ribonucleoside triphosphate phosphatase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0009134 nucleoside diphosphate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "F1QCU4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QCY8-1", "uniprot_id": [ { "id": "SPAT2_DANRE", "url": "https://www.uniprot.org/uniprot/F1QCY8", "type": "external" } ], "mass": 60648.0, "length": 550, "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "spata2", "organism": "Zebrafish", "refseq_name": "spermatogenesis-associated protein 2", "refseq_ac": [ { "id": "NP_001073660", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073660", "type": "external" } ], "gene_names_uniprotkb": "spata2; zgc:165341", "gene_names_refseq": "spata2; zgc:165341", "protein_names_uniprotkb": "Spermatogenesis-associated protein 2", "protein_names_refseq": "spermatogenesis associated protein 2; spermatogenesis-associated protein 2", "tax_id": 7955, "disease": "", "pathway": " (dre:568830); (R-DRE-5357786); (R-DRE-5357905)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "17486545;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC150216.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC150216.1. On Dec 30, 2008 this sequence version replaced NP_001073660.1., [RefSeq]; Bridging factor that mediates the recruitment of cyld to the LUBAC complex, thereby regulating TNF-induced necroptosis. Required to activate the 'Met-1'- (linear) and 'Lys-63'-linked deubiquitinase activities of cyld., [UniProtKB, UniProtKB]; Zebrafish spata2 is expressed at early developmental stages., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1YAC7;A7E269", "ec_number_list": [], "go_molecular_function": "GO:0030159 signaling receptor complex adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0070536 protein K63-linked deubiquitination;GO:0050727 regulation of inflammatory response;GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway;GO:0060544 regulation of necroptotic process;GO:1990108 protein linear deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1QCY8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QD35-1", "uniprot_id": [ { "id": "F1QD35_DANRE", "url": "https://www.uniprot.org/uniprot/F1QD35", "type": "external" } ], "mass": 56737.0, "length": 508, "protein_name": "2.3.1.51; Lysophospholipid acyltransferase LPCAT4", "gene_name": "lpcat4", "organism": "Zebrafish", "refseq_name": "lysophospholipid acyltransferase LPCAT4", "refseq_ac": [ { "id": "NP_991122", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_991122", "type": "external" } ], "gene_names_uniprotkb": "lpcat4; wu:fb10c07; wu:fi17g10; zgc:77292", "gene_names_refseq": "lpcat4; wu:fb10c07; wu:fi17g10; zgc:77292", "protein_names_uniprotkb": "2.3.1.51; Lysophospholipid acyltransferase LPCAT4", "protein_names_refseq": "lysophospholipid acyltransferase LPCAT4", "tax_id": 7955, "disease": "", "pathway": " (dre:327566); (R-DRE-1482788); (R-DRE-1482801); (R-DRE-1482839); (R-DRE-1482925); (R-DRE-1483166)", "pathway_count": 6, "publication_count": 5, "publication_id_list": "26469318;27189481;31950220;32798906;36290180", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01025427.1, BC065948.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH483770.1, EH541464.1, JBMGRA010000007.1 and FP139120.1. On Jul 8, 2011 this sequence version replaced NP_991122.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PGC0", "ec_number_list": [ { "id": "2.3.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.51", "type": "external" }, { "id": "2.3.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.23", "type": "external" }, { "id": "2.3.1.67", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.67", "type": "external" }, { "id": "2.3.1.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.25", "type": "external" }, { "id": "2.3.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.15", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" } ], "go_molecular_function": "GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0042171 lysophosphatidic acid acyltransferase activity;GO:0005509 calcium ion binding;GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0008654 phospholipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F1QD35-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QDE0-1", "uniprot_id": [ { "id": "F1QDE0_DANRE", "url": "https://www.uniprot.org/uniprot/F1QDE0", "type": "external" } ], "mass": 31612.0, "length": 288, "protein_name": "Mitochondrial dicarboxylate carrier", "gene_name": "slc25a10a", "organism": "Zebrafish", "refseq_name": "mitochondrial dicarboxylate carrier isoform X1", "refseq_ac": [ { "id": "XP_002661286", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002661286", "type": "external" } ], "gene_names_uniprotkb": "slc25a10a", "gene_names_refseq": "slc25a10a", "protein_names_uniprotkb": "Mitochondrial dicarboxylate carrier; Solute carrier family 25 member 10", "protein_names_refseq": "mitochondrial dicarboxylate carrier isoform X1", "tax_id": 7955, "disease": "mitochondrial DNA depletion syndrome 19 (Disease Ontology:DOID:0070450)", "pathway": " (dre:100332610)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the electroneutral exchange or flux of physiologically important metabolites such as dicarboxylates (malonate, malate, succinate), inorganic sulfur-containing anions, and phosphate, across the mitochondrial inner membrane. Substrate exchange across the membrane occurs consecutively with one substrate being transported first, then dissociating from the substrate binding site before the second substrate binds for transport in the opposite direction. Does not transport glutathione. Plays an important role in gluconeogenesis, fatty acid metabolism, urea synthesis, and sulfur metabolism, particularly in liver, by supplying the substrates for the different metabolic processes. Regulates fatty acid release from adipocytes, and contributes to systemic insulin sensitivity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RK11", "ec_number_list": [], "go_molecular_function": "GO:0015297 antiporter activity;GO:0015116 sulfate transmembrane transporter activity;GO:0015117 thiosulfate transmembrane transporter activity;GO:0015131 oxaloacetate transmembrane transporter activity;GO:0015140 malate transmembrane transporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006869 lipid transport;GO:1902358 sulfate transmembrane transport;GO:0015709 thiosulfate transport;GO:0015729 oxaloacetate transport;GO:0035435 phosphate ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QDE0-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QDF0-1", "uniprot_id": [ { "id": "F1QDF0_DANRE", "url": "https://www.uniprot.org/uniprot/F1QDF0", "type": "external" } ], "mass": 103562.0, "length": 921, "protein_name": "Kinesin-like protein", "gene_name": "kif20a", "organism": "Zebrafish", "refseq_name": "kinesin-like protein KIF20A", "refseq_ac": [ { "id": "NP_001154942", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001154942", "type": "external" } ], "gene_names_uniprotkb": "kif20a; wu:fi34h02; wu:fj10c11; zgc:112061", "gene_names_refseq": "kif20a; wu:fi34h02; wu:fj10c11; zgc:112061", "protein_names_uniprotkb": "Kinesin-like protein", "protein_names_refseq": "kinesin-like protein KIF20A", "tax_id": 7955, "disease": "familial restrictive cardiomyopathy 6 (Disease Ontology:DOID:0061025)", "pathway": " (dre:325449); (R-DRE-68884)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "15245916;15984772;16690118;16799861;18477665;18987288;26469318;27189481;29357359;32848183", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC095661.1, SRR26395014.766280.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Jun 25, 2025 this sequence version replaced NP_001154942.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NT09", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005819 spindle;GO:0005874 microtubule;GO:0005871 kinesin complex", "go_biological_process": "GO:0007507 heart development;GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QDF0-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QDI9-1", "uniprot_id": [ { "id": "MCM9_DANRE", "url": "https://www.uniprot.org/uniprot/F1QDI9", "type": "external" } ], "mass": 125662.0, "length": 1133, "protein_name": "DNA helicase MCM9", "gene_name": "mcm9", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "mcm9; mcmdc1; si:ch211-112m17.2", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA helicase MCM9; 5.6.2.4; DNA 3'-5' helicase MCM9; Minichromosome maintenance 9", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex is a 3'-5' DNA helicase and single-stranded (ss)DNA-stimulated ATPase which binds ssDNA in the presence of nucleoside triphosphates. It probably processes aberrant forks into homologous recombination substrates and orchestrates homologous recombination with resection, fork stabilization and fork restart (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0043138 3'-5' DNA helicase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0097362 MCM8-MCM9 complex;GO:0042555 MCM complex", "go_biological_process": "GO:0006260 DNA replication;GO:0006974 DNA damage response;GO:0000724 double-strand break repair via homologous recombination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1QDI9-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QE32-1", "uniprot_id": [ { "id": "F1QE32_DANRE", "url": "https://www.uniprot.org/uniprot/F1QE32", "type": "external" } ], "mass": 23660.0, "length": 204, "protein_name": "Protein unc-119 homolog A", "gene_name": "unc119a1", "organism": "Zebrafish", "refseq_name": "protein unc-119 homolog A", "refseq_ac": [ { "id": "XP_695204", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695204", "type": "external" } ], "gene_names_uniprotkb": "unc119a1", "gene_names_refseq": "unc119a1", "protein_names_uniprotkb": "Protein unc-119 homolog A", "protein_names_refseq": "protein unc-119 homolog A", "tax_id": 7955, "disease": "cone-rod dystrophy 24 (Disease Ontology:DOID:0081449); immunodeficiency 13 (Disease Ontology:DOID:0111987)", "pathway": " (dre:566824)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid-binding chaperone with specificity for a diverse subset of myristoylated proteins. Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Probably plays a role in trafficking proteins in photoreceptor cells. Plays important roles in mediating Src family kinase signals for the completion of cytokinesis via RAB11A., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7T7Q5", "ec_number_list": [], "go_molecular_function": "GO:0008289 lipid binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005813 centrosome;GO:0051233 spindle midzone;GO:0045171 intercellular bridge", "go_biological_process": "GO:0006897 endocytosis;GO:0007399 nervous system development;GO:0042953 lipoprotein transport;GO:0007601 visual perception;GO:0000281 mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QE32-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QE83-1", "uniprot_id": [ { "id": "F1QE83_DANRE", "url": "https://www.uniprot.org/uniprot/F1QE83", "type": "external" } ], "mass": 121561.0, "length": 1097, "protein_name": "Inactive serine protease PAMR1", "gene_name": "pamr1b", "organism": "Zebrafish", "refseq_name": "inactive serine protease PAMR1 isoform X1", "refseq_ac": [ { "id": "XP_009296508", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009296508", "type": "external" } ], "gene_names_uniprotkb": "pamr1b", "gene_names_refseq": "pamr1b", "protein_names_uniprotkb": "Inactive serine protease PAMR1; Peptidase domain-containing protein associated with muscle regeneration 1; Regeneration-associated muscle protease homolog", "protein_names_refseq": "inactive serine protease PAMR1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100330319)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May play a role in regeneration of skeletal muscle., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AWV1", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QE83-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QEB4-1", "uniprot_id": [ { "id": "F1QEB4_DANRE", "url": "https://www.uniprot.org/uniprot/F1QEB4", "type": "external" } ], "mass": 79667.0, "length": 705, "protein_name": "FACT complex subunit SSRP1", "gene_name": "ssrp1a", "organism": "Zebrafish", "refseq_name": "FACT complex subunit SSRP1a isoform 1", "refseq_ac": [ { "id": "NP_997967", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997967", "type": "external" } ], "gene_names_uniprotkb": "ssrp1a; ssrp1; wu:fa11b03; wu:fd10f06", "gene_names_refseq": "ssrp1a; ssrp1; wu:fa11b03; wu:fd10f06", "protein_names_uniprotkb": "FACT complex subunit SSRP1", "protein_names_refseq": "FACT complex subunit SSRP1a isoform 1; structure specific recognition protein 1", "tax_id": 7955, "disease": "", "pathway": " (dre:386844); (R-DRE-674695); (R-DRE-6796648); (R-DRE-6804756); (R-DRE-75955); (R-DRE-9943411)", "pathway_count": 6, "publication_count": 8, "publication_id_list": "20603019;23515471;24240475;25014315;25556858;30631305;31036921;33230303", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01007068.1, BC056311.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Dec 4, 2025 this sequence version replaced NP_997967.2., [RefSeq]; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. Binds specifically to double-stranded DNA., [UniProtKB, UniProtKB]; Ssrp1a is essential for proliferation and differentiation during eye and liver organogenesis., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PHY6", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0042393 histone binding;GO:0031491 nucleosome binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0035101 FACT complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0006260 DNA replication;GO:0051726 regulation of cell cycle;GO:1902275 regulation of chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "F1QEB4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QEG1-1", "uniprot_id": [ { "id": "F1QEG1_DANRE", "url": "https://www.uniprot.org/uniprot/F1QEG1", "type": "external" } ], "mass": 160028.0, "length": 1482, "protein_name": "P-type Cu(+) transporter", "gene_name": "atp7a", "organism": "Zebrafish", "refseq_name": "copper-transporting ATPase 1 isoform X1", "refseq_ac": [ { "id": "XP_005173182", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173182", "type": "external" } ], "gene_names_uniprotkb": "atp7a; cal; wu:fc43e01; zgc:153422; zgc:158633", "gene_names_refseq": "atp7a; cal; wu:fc43e01; zgc:153422; zgc:158633", "protein_names_uniprotkb": "P-type Cu(+) transporter; 7.2.2.8", "protein_names_refseq": "copper-transporting ATPase 1 isoform X1", "tax_id": 7955, "disease": "X-linked distal spinal muscular atrophy 3 (Disease Ontology:DOID:0111196); occipital horn syndrome (Disease Ontology:DOID:0111272); Alzheimer's disease (Disease Ontology:DOID:10652); iron deficiency anemia (Disease Ontology:DOID:11758); spinal muscular atrophy (Disease Ontology:DOID:12377); Menkes disease (Disease Ontology:DOID:1838); cutis laxa (Disease Ontology:DOID:3144); aortic aneurysm (Disease Ontology:DOID:3627); congenital diaphragmatic hernia (Disease Ontology:DOID:3827); osteoarthritis (Disease Ontology:DOID:8398); Wilson disease (Disease Ontology:DOID:893); metal metabolism disorder (Disease Ontology:DOID:896)", "pathway": " (R-DRE-6803544); (R-DRE-936837)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BKF6;A0AC58H6I5;A0AC58H6I7", "ec_number_list": [ { "id": "7.2.2.8", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.8", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0005507 copper ion binding;GO:0043682 P-type divalent copper transporter activity;GO:0140581 P-type monovalent copper transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0006878 intracellular copper ion homeostasis;GO:0046688 response to copper ion;GO:0015677 copper ion import;GO:0060003 copper ion export;GO:0010038 response to metal ion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QEG1-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QM29-1", "uniprot_id": [ { "id": "F1QM29_DANRE", "url": "https://www.uniprot.org/uniprot/F1QM29", "type": "external" } ], "mass": 156691.0, "length": 1413, "protein_name": "X-linked retinitis pigmentosa GTPase regulator", "gene_name": "rpgrb", "organism": "Zebrafish", "refseq_name": "retinitis pigmentosa GTPase regulator b isoform 1", "refseq_ac": [ { "id": "NP_001299605", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001299605", "type": "external" } ], "gene_names_uniprotkb": "rpgrb", "gene_names_refseq": "rpgrb", "protein_names_uniprotkb": "X-linked retinitis pigmentosa GTPase regulator", "protein_names_refseq": "retinitis pigmentosa GTPase regulator b isoform 1; rpgr2", "tax_id": 7955, "disease": "retinitis pigmentosa 3 (Disease Ontology:DOID:0110414); X-linked cone-rod dystrophy 1 (Disease Ontology:DOID:0111008); X-linked retinitis pigmentosa and sinorespiratory infections (Disease Ontology:DOID:0112124); X-linked atrophic macular degeneration (Disease Ontology:DOID:0112157); retinitis pigmentosa (Disease Ontology:DOID:10584)", "pathway": " (dre:557752)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "19815619;19955120;23536988;24043777;26431479;26469318;27189481;32911150", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01033043.1, GU012648.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476729, SAMEA4476730 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1 and EH442709.1. On Aug 15, 2015 this sequence version replaced XP_685964.5. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Rpgr2 is required for normal retinal development and plays a role in dynein-based retrograde transport processes. [Rpgr2], [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P1U8;A0AC58GQP1", "ec_number_list": [], "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005794 Golgi apparatus;GO:0005813 centrosome;GO:0005929 cilium", "go_biological_process": "GO:0007601 visual perception;GO:0060041 retina development in camera-type eye;GO:0060271 cilium assembly;GO:0007018 microtubule-based movement;GO:0010842 retina layer formation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "F1QM29-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QEZ8-1", "uniprot_id": [ { "id": "F1QEZ8_DANRE", "url": "https://www.uniprot.org/uniprot/F1QEZ8", "type": "external" } ], "mass": 138735.0, "length": 1254, "protein_name": "Neurocan core protein", "gene_name": "ncanb", "organism": "Zebrafish", "refseq_name": "neurocan core protein", "refseq_ac": [ { "id": "XP_017208935", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208935", "type": "external" } ], "gene_names_uniprotkb": "ncanb", "gene_names_refseq": "ncanb", "protein_names_uniprotkb": "Neurocan core protein; Chondroitin sulfate proteoglycan 3", "protein_names_refseq": "neurocan core protein", "tax_id": 7955, "disease": "", "pathway": " (dre:559024); (R-DRE-1971475); (R-DRE-2022870); (R-DRE-2022923); (R-DRE-2024101); (R-DRE-3000178)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan; binds to hyaluronic acid., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z4B2;A0AC58II11;A0AC58II21;A0AC58II29", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0030246 carbohydrate binding;GO:0005540 hyaluronic acid binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0045202 synapse;GO:0072534 perineuronal net", "go_biological_process": "GO:0007155 cell adhesion;GO:0007417 central nervous system development;GO:0001501 skeletal system development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QEZ8-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QFA1-1", "uniprot_id": [ { "id": "F1QFA1_DANRE", "url": "https://www.uniprot.org/uniprot/F1QFA1", "type": "external" } ], "mass": 43899.0, "length": 398, "protein_name": "Probable proton-coupled zinc antiporter SLC30A3", "gene_name": "slc30a2", "organism": "Zebrafish", "refseq_name": "zinc transporter 2 isoform X1", "refseq_ac": [ { "id": "XP_009293168", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009293168", "type": "external" } ], "gene_names_uniprotkb": "slc30a2; si:ch211-243j20.1", "gene_names_refseq": "si:ch211-243j20.1; slc30a2", "protein_names_uniprotkb": "Probable proton-coupled zinc antiporter SLC30A3; Proton-coupled zinc antiporter SLC30A2; Solute carrier family 30 member 2; Solute carrier family 30 member 3; Zinc transporter 2; Zinc transporter 3", "protein_names_refseq": "zinc transporter 2 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:563540)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "16500426;16689696;18477665;21596156;22912764;23862018;24301558;28837703;30851936;32423892", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Electroneutral proton-coupled antiporter concentrating zinc ions into a variety of intracellular organelles including endosomes, zymogen granules and mitochondria. Thereby, plays a crucial role in cellular zinc homeostasis to confer upon cells protection against its potential cytotoxicity. Regulates the zinc concentration of milk, through the transport of zinc ions into secretory vesicles of mammary cells. By concentrating zinc ions into lysosomes participates to lysosomal-mediated cell death during early mammary gland involution., [UniProtKB, UniProtKB, UniProtKB]; Probable proton-coupled zinc ion antiporter mediating the import of zinc from cytoplasm into synaptic vesicles and participating to cellular zinc ion homeostasis in the brain., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AL21;A0AC58I404;A0AC58I406", "ec_number_list": [], "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity;GO:0046872 metal ion binding;GO:0015297 antiporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005886 plasma membrane;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0071577 zinc ion transmembrane transport;GO:0006829 zinc ion transport;GO:0010043 response to zinc ion;GO:0062111 zinc ion import into organelle", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QFA1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QFF1-1", "uniprot_id": [ { "id": "F1QFF1_DANRE", "url": "https://www.uniprot.org/uniprot/F1QFF1", "type": "external" } ], "mass": 40353.0, "length": 356, "protein_name": "Lysophosphatidic acid receptor 2a isoform X1", "gene_name": "lpar2a", "organism": "Zebrafish", "refseq_name": "lysophosphatidic acid receptor 2a isoform X1", "refseq_ac": [ { "id": "XP_009298048", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009298048", "type": "external" } ], "gene_names_uniprotkb": "lpar2a; zgc:101053", "gene_names_refseq": "lpar2a; zgc:101053", "protein_names_uniprotkb": "Lysophosphatidic acid receptor 2a isoform X1", "protein_names_refseq": "lysophosphatidic acid receptor 2a isoform X1", "tax_id": 7955, "disease": "", "pathway": " (R-DRE-416476); (R-DRE-418594); (R-DRE-419408)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AYC3", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0070915 lysophosphatidic acid receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0001525 angiogenesis;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0045647 negative regulation of erythrocyte differentiation;GO:0002574 thrombocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QFF1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QFN6-1", "uniprot_id": [ { "id": "F1QFN6_DANRE", "url": "https://www.uniprot.org/uniprot/F1QFN6", "type": "external" } ], "mass": 38935.0, "length": 346, "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "rffl", "organism": "Zebrafish", "refseq_name": "E3 ubiquitin-protein ligase rififylin isoform X1", "refseq_ac": [ { "id": "XP_009289725", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009289725", "type": "external" } ], "gene_names_uniprotkb": "rffl; zgc:77828", "gene_names_refseq": "rffl; zgc:77828", "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase rififylin isoform X1", "tax_id": 7955, "disease": "hypertension (Disease Ontology:DOID:10763)", "pathway": " (R-DRE-6804757)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3ASF4", "ec_number_list": [ { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0006915 apoptotic process;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QFN6-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QFQ7-1", "uniprot_id": [ { "id": "F1QFQ7_DANRE", "url": "https://www.uniprot.org/uniprot/F1QFQ7", "type": "external" } ], "mass": 46599.0, "length": 422, "protein_name": "Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial", "gene_name": "acadsb", "organism": "Zebrafish", "refseq_name": "short/branched chain specific acyl-CoA dehydrogenase, mitochondrial", "refseq_ac": [ { "id": "NP_001338578", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338578", "type": "external" } ], "gene_names_uniprotkb": "acadsb; zgc:162918", "gene_names_refseq": "acadsb; zgc:162918", "protein_names_uniprotkb": "Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial; 1.3.8.1; 1.3.8.5; 2-methyl branched chain acyl-CoA dehydrogenase; 2-methylbutyryl-coenzyme A dehydrogenase", "protein_names_refseq": "short/branched chain specific acyl-CoA dehydrogenase, mitochondrial-like; short/branched chain specific acyl-CoA dehydrogenase, mitochondrial", "tax_id": 7955, "disease": "", "pathway": " (dre:110437777); (R-DRE-70895); (R-DRE-9837999)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "17371995;25014315;26469318;27189481;28252024", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01000252.1, SRR26395062.1570565.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1. On Aug 3, 2017 this sequence version replaced XP_021336129.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Short and branched chain specific acyl-CoA dehydrogenase that catalyzes the proR-proR stereospecific alpha,beta-dehydrogenation of fatty acyl-CoA thioesters using the electron transfer flavoprotein (ETF) as their physiologic electron acceptor, resulting in the formation of trans-2-enoyl-CoA ((2E)-enoyl-CoA). Among the different mitochondrial acyl-CoA dehydrogenases, acts specifically on short and branched chain acyl-CoA derivatives such as (S)-2-methylbutyryl-CoA as well as short straight chain acyl-CoAs such as butyryl-CoA (butanoyl-CoA). Plays an important role in the metabolism of L-isoleucine by catalyzing the dehydrogenation of 2-methylbutyryl-CoA, one of the steps of the L-isoleucine catabolic pathway. Can also act on valproyl-CoA, a metabolite of valproic acid, an antiepileptic drug., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9QF25", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "1.3.8.7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.7", "type": "external" }, { "id": "1.2.4.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.4.2", "type": "external" }, { "id": "2.7.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.-", "type": "external" }, { "id": "1.3.8.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.1", "type": "external" }, { "id": "1.3.8.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.5", "type": "external" }, { "id": "2.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.9", "type": "external" }, { "id": "4.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.2", "type": "external" }, { "id": "2.3.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.1", "type": "external" } ], "go_molecular_function": "GO:0003995 acyl-CoA dehydrogenase activity;GO:0050660 flavin adenine dinucleotide binding;GO:0003853 short-chain 2-methyl fatty acyl-CoA dehydrogenase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0046395 carboxylic acid catabolic process;GO:0006631 fatty acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F1QFQ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QFR9-1", "uniprot_id": [ { "id": "PSM4A_DANRE", "url": "https://www.uniprot.org/uniprot/F1QFR9", "type": "external" } ], "mass": 211144.0, "length": 1833, "protein_name": "Proteasome activator complex subunit 4A", "gene_name": "psme4a", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "psme4a", "gene_names_refseq": "", "protein_names_uniprotkb": "Proteasome activator complex subunit 4A; Proteasome activator PA200-A", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. Involved in DNA damage response in somatic cells: binds to acetylated histones and promotes degradation of histones (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "E7F2L9", "ec_number_list": [], "go_molecular_function": "GO:0016504 peptidase activator activity;GO:0070628 proteasome binding", "go_cellular_component": "GO:1990111 spermatoproteasome complex;GO:0005634 nucleus;GO:0005829 cytosol;GO:0016607 nuclear speck", "go_biological_process": "GO:0006281 DNA repair;GO:0006974 DNA damage response;GO:0010499 proteasomal ubiquitin-independent protein catabolic process;GO:0035092 sperm DNA condensation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1QFR9-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QG70-1", "uniprot_id": [ { "id": "F1QG70_DANRE", "url": "https://www.uniprot.org/uniprot/F1QG70", "type": "external" } ], "mass": 37598.0, "length": 326, "protein_name": "stearoyl-CoA 9-desaturase", "gene_name": "scd", "organism": "Zebrafish", "refseq_name": "acyl-CoA desaturase", "refseq_ac": [ { "id": "NP_942110", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_942110", "type": "external" } ], "gene_names_uniprotkb": "scd; SCD1", "gene_names_refseq": "SCD1; scd", "protein_names_uniprotkb": "stearoyl-CoA 9-desaturase; 1.14.19.1", "protein_names_refseq": "acyl-CoA desaturase", "tax_id": 7955, "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); autosomal dominant nonsyndromic deafness 79 (Disease Ontology:DOID:0112160); hyperinsulinism (Disease Ontology:DOID:2018); carcinoma (Disease Ontology:DOID:305); restrictive cardiomyopathy (Disease Ontology:DOID:397)", "pathway": " (dre:386661); (R-DRE-75105)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "14579408;18297735;18593860;18728227;18963085;37305084;38449808;38485505;38699158;38788853", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01004217.1, GFIL01034546.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476751, SAMEA4476784 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1. On Jun 25, 2025 this sequence version replaced NP_942110.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Whole-mount in situ hybridization and real-time quantitative RT-PCR to identify expression of the zebrafish SCD gene at five different stages of development, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P985", "ec_number_list": [ { "id": "1.14.19.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.19.1", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0004768 stearoyl-CoA 9-desaturase activity;GO:0032896 palmitoyl-CoA 9-desaturase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006636 unsaturated fatty acid biosynthetic process;GO:1903966 monounsaturated fatty acid biosynthetic process;GO:0036269 swimming behavior;GO:0060613 fat pad development", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QG70-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QG83-1", "uniprot_id": [ { "id": "F1QG83_DANRE", "url": "https://www.uniprot.org/uniprot/F1QG83", "type": "external" } ], "mass": 36046.0, "length": 323, "protein_name": "Novel immune-type receptor 1m precursor", "gene_name": "nitr1m", "organism": "Zebrafish", "refseq_name": "novel immune-type receptor 1m precursor", "refseq_ac": [ { "id": "NP_001296747", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001296747", "type": "external" } ], "gene_names_uniprotkb": "nitr1m; nitr1.24; nitr1.42; nitr1.45; nitr1.53; nitr1.9; nitr1m_2; nitr1m_5; nitr1; si:busm1-219h16.10; si:busm1-263j20.8; si:dz219h16.10; si:dz263j20.8", "gene_names_refseq": "nitr1.24; nitr1.42; nitr1.45; nitr1.53; nitr1.9; nitr1m_2; nitr1m_5; nitr1m; nitr1; si:busm1-219h16.10; si:busm1-263j20.8; si:dz219h16.10; si:dz263j20.8", "protein_names_uniprotkb": "Novel immune-type receptor 1m precursor", "protein_names_refseq": "novel immune-type receptor 1.24; novel immune-type receptor 1.9; novel immune-type receptor 1m precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:170971)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "18565225;20012603", "class_list": "", "function": "##Evidence-Data-START## CDS exon combination :: BC163831.1 [ECO:0000331] RNAseq introns :: partial sample support SAMN06350655, SAMN06645146 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Dec 1, 2025 this sequence version replaced NP_001296747.1. Sequence Note:., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P1P2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0002376 immune system process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1QG83-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QGD2-1", "uniprot_id": [ { "id": "ZDH24_DANRE", "url": "https://www.uniprot.org/uniprot/F1QGD2", "type": "external" } ], "mass": 33721.0, "length": 295, "protein_name": "Probable palmitoyltransferase ZDHHC24", "gene_name": "zdhhc24", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "zdhhc24; dhhc24", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable palmitoyltransferase ZDHHC24; 2.3.1.225; DHHC domain-containing cysteine-rich protein 24; Zinc finger DHHC domain-containing protein 24", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "23594743;26056731;27235108", "class_list": "", "function": "Probable palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A7YYE7", "ec_number_list": [ { "id": "2.3.1.225", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.225", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" } ], "go_molecular_function": "GO:0019706 protein-cysteine S-palmitoyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016020 membrane", "go_biological_process": "GO:0006612 protein targeting to membrane", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1QGD2-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QGH6-1", "uniprot_id": [ { "id": "AMER2_DANRE", "url": "https://www.uniprot.org/uniprot/F1QGH6", "type": "external" } ], "mass": 69090.0, "length": 654, "protein_name": "APC membrane recruitment protein 2", "gene_name": "amer2", "organism": "Zebrafish", "refseq_name": "APC membrane recruitment protein 2", "refseq_ac": [ { "id": "NP_001093622", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093622", "type": "external" } ], "gene_names_uniprotkb": "amer2; fam123a; zgc:165647", "gene_names_refseq": "amer2; fam123a; zgc:165647", "protein_names_uniprotkb": "APC membrane recruitment protein 2; Amer2; Protein FAM123A", "protein_names_refseq": "APC membrane recruitment protein 2; family with sequence similarity 123A", "tax_id": 7955, "disease": "", "pathway": " (dre:100101649)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC146746.1 [ECO:0000332] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC146746.1., [RefSeq]; Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A6H8T6", "ec_number_list": [], "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0016055 Wnt signaling pathway;GO:0060828 regulation of canonical Wnt signaling pathway;GO:0007398 ectoderm development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1QGH6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QGH9-1", "uniprot_id": [ { "id": "PS11B_DANRE", "url": "https://www.uniprot.org/uniprot/F1QGH9", "type": "external" } ], "mass": 47577.0, "length": 422, "protein_name": "26S proteasome non-ATPase regulatory subunit 11B", "gene_name": "psmd11b", "organism": "Zebrafish", "refseq_name": "26S proteasome non-ATPase regulatory subunit 11B", "refseq_ac": [ { "id": "NP_955886", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_955886", "type": "external" } ], "gene_names_uniprotkb": "psmd11b", "gene_names_refseq": "psmd11b; psmd11; wu:fb55b06; zgc:56580; zgc:77763", "protein_names_uniprotkb": "26S proteasome non-ATPase regulatory subunit 11B; 26S proteasome regulatory subunit RPN6-B", "protein_names_refseq": "26S proteasome non-ATPase regulatory subunit 11B; 26S proteasome regulatory subunit RPN6-B; proteasome (prosome, macropain) 216S subunit, non-ATPase, 11b; proteasome (prosome, macropain) 26S subunit, non-ATPase, 11b; proteasome (prosome, macropain) 26S subunit, non-ATPase, 11", "tax_id": 7955, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888)", "pathway": " (dre:322265); (R-DRE-1169091); (R-DRE-1234176); (R-DRE-1236978); (R-DRE-174084); (R-DRE-174154); (R-DRE-174178); (R-DRE-174184); (R-DRE-187577); (R-DRE-195253); (R-DRE-2467813); (R-DRE-349425); (R-DRE-350562); (R-DRE-382556); (R-DRE-450408); (R-DRE-4608870); (R-DRE-4641257); (R-DRE-4641258); (R-DRE-5358346); (R-DRE-5610780); (R-DRE-5610785); (R-DRE-5632684); (R-DRE-5658442); (R-DRE-5668541); (R-DRE-5687128); (R-DRE-5689603); (R-DRE-5689880); (R-DRE-6798695); (R-DRE-68867); (R-DRE-68949); (R-DRE-69017); (R-DRE-69481); (R-DRE-69601); (R-DRE-75815); (R-DRE-8852276); (R-DRE-8854050); (R-DRE-8939236); (R-DRE-8939902); (R-DRE-8941858); (R-DRE-8948751); (R-DRE-8951664); (R-DRE-9755511); (R-DRE-9762114); (R-DRE-9766229); (R-DRE-983168); (R-DRE-9907900); (R-DRE-9929491); (R-DRE-9932298); (R-DRE-9954709)", "pathway_count": 49, "publication_count": 2, "publication_id_list": "23594743;40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01001558.1, BC063978.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505374, SAMEA3505376 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1., [RefSeq]; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, psmd11b is required for proteasome assembly (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7ZTZ8", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0022624 proteasome accessory complex;GO:0005634 nucleus;GO:0005829 cytosol;GO:0008541 proteasome regulatory particle, lid subcomplex", "go_biological_process": "GO:0048863 stem cell differentiation;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0043248 proteasome assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F1QGH9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QGS9-1", "uniprot_id": [ { "id": "F1QGS9_DANRE", "url": "https://www.uniprot.org/uniprot/F1QGS9", "type": "external" } ], "mass": 72883.0, "length": 644, "protein_name": "Beta-glucuronidase", "gene_name": "gusb", "organism": "Zebrafish", "refseq_name": "beta-glucuronidase", "refseq_ac": [ { "id": "XP_009299404", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009299404", "type": "external" } ], "gene_names_uniprotkb": "gusb", "gene_names_refseq": "gusb", "protein_names_uniprotkb": "Beta-glucuronidase; 3.2.1.31", "protein_names_refseq": "beta-glucuronidase", "tax_id": 7955, "disease": "mucopolysaccharidosis type VII (Disease Ontology:DOID:12803)", "pathway": " (dre:571441); (R-DRE-2024101); (R-DRE-2160916); (R-DRE-6798695)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays an important role in the degradation of dermatan and keratan sulfates., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AZ75", "ec_number_list": [ { "id": "2.7.1.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.11", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.4.21.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.4", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.1", "type": "external" }, { "id": "3.1.27.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.27.-", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "5.4.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.11", "type": "external" }, { "id": "5.4.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.4", "type": "external" }, { "id": "1.13.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:1.13.11.34", "type": "external" }, { "id": "4.6.1.19", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.19", "type": "external" }, { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "3.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.-", "type": "external" }, { "id": "3.2.1.31", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.31", "type": "external" }, { "id": "5.3.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.4.1", "type": "external" }, { "id": "3.1.6.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.4", "type": "external" }, { "id": "3.5.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.4", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "6.3.4.21", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.21", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "5.3.99.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.3", "type": "external" }, { "id": "1.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.5.5", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" } ], "go_molecular_function": "GO:0030246 carbohydrate binding;GO:0004566 beta-glucuronidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005764 lysosome", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0030207 chondroitin sulfate proteoglycan catabolic process;GO:0030200 heparan sulfate proteoglycan catabolic process;GO:0030214 hyaluronan catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QGS9-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QGW0-1", "uniprot_id": [ { "id": "F1QGW0_DANRE", "url": "https://www.uniprot.org/uniprot/F1QGW0", "type": "external" } ], "mass": 50296.0, "length": 444, "protein_name": "Gamma-aminobutyric acid receptor subunit alpha-6 isoform X1", "gene_name": "gabra6b", "organism": "Zebrafish", "refseq_name": "gamma-aminobutyric acid receptor subunit alpha-6 isoform X1", "refseq_ac": [ { "id": "XP_002667403", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002667403", "type": "external" } ], "gene_names_uniprotkb": "gabra6b", "gene_names_refseq": "gabra6b", "protein_names_uniprotkb": "Gamma-aminobutyric acid receptor subunit alpha-6 isoform X1", "protein_names_refseq": "gamma-aminobutyric acid receptor subunit alpha-6 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:559693); (R-DRE-977443)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_002667403.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RI99", "ec_number_list": [], "go_molecular_function": "GO:0004890 GABA-A receptor activity;GO:0022851 GABA-gated chloride ion channel activity", "go_cellular_component": "GO:0045211 postsynaptic membrane;GO:0098794 postsynapse;GO:0034707 chloride channel complex;GO:0032590 dendrite membrane;GO:1902711 GABA-A receptor complex", "go_biological_process": "GO:0007214 gamma-aminobutyric acid signaling pathway;GO:1902476 chloride transmembrane transport;GO:0051932 synaptic transmission, GABAergic;GO:1904862 inhibitory synapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QGW0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QGX0-1", "uniprot_id": [ { "id": "F1QGX0_DANRE", "url": "https://www.uniprot.org/uniprot/F1QGX0", "type": "external" } ], "mass": 85198.0, "length": 782, "protein_name": "Integrin beta", "gene_name": "itgb6", "organism": "Zebrafish", "refseq_name": "integrin beta-6 isoform X1", "refseq_ac": [ { "id": "XP_003199474", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003199474", "type": "external" } ], "gene_names_uniprotkb": "itgb6", "gene_names_refseq": "itgb6", "protein_names_uniprotkb": "Integrin beta", "protein_names_refseq": "integrin beta-6 isoform X1", "tax_id": 7955, "disease": "amelogenesis imperfecta type 1H (Disease Ontology:DOID:0110064); cancer (Disease Ontology:DOID:162); asthma (Disease Ontology:DOID:2841); liver cirrhosis (Disease Ontology:DOID:5082); pulmonary emphysema (Disease Ontology:DOID:9675)", "pathway": " (dre:100499533); (R-DRE-1566948); (R-DRE-2129379); (R-DRE-216083); (R-DRE-2173789); (R-DRE-3000178)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B2H5", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005925 focal adhesion;GO:0009986 cell surface;GO:0034685 integrin alphav-beta6 complex", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0016477 cell migration;GO:0007160 cell-matrix adhesion;GO:0033627 cell adhesion mediated by integrin;GO:0098609 cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QGX0-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QH59-1", "uniprot_id": [ { "id": "F1QH59_DANRE", "url": "https://www.uniprot.org/uniprot/F1QH59", "type": "external" } ], "mass": 42267.0, "length": 394, "protein_name": "mRNA decay activator protein ZFP36", "gene_name": "fb92b09", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC570332", "refseq_ac": [ { "id": "NP_001025418", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025418", "type": "external" } ], "gene_names_uniprotkb": "fb92b09; wu:fb92b09; zgc:114130", "gene_names_refseq": "fb92b09; wu:fb92b09; zgc:114130", "protein_names_uniprotkb": "mRNA decay activator protein ZFP36; Zinc finger protein 36", "protein_names_refseq": "uncharacterized protein LOC570332", "tax_id": 7955, "disease": "", "pathway": " (dre:570332); (R-DRE-450513)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "25556858;27189481;35600071", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC097188.1, GDQQ01002327.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On or before Jul 3, 2024 this sequence version replaced XP_005173441.1, NP_001025418.1., [RefSeq]; Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BKP1", "ec_number_list": [], "go_molecular_function": "GO:0000900 mRNA regulatory element binding translation repressor activity;GO:0008270 zinc ion binding;GO:0035925 mRNA 3'-UTR AU-rich region binding;GO:0160134 protein-RNA sequence-specific adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening;GO:0061158 3'-UTR-mediated mRNA destabilization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1QH59-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QH81-1", "uniprot_id": [ { "id": "F1QH81_DANRE", "url": "https://www.uniprot.org/uniprot/F1QH81", "type": "external" } ], "mass": 25382.0, "length": 233, "protein_name": "Claudin", "gene_name": "cldn10b", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC100004456", "refseq_ac": [ { "id": "NP_001018449", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018449", "type": "external" } ], "gene_names_uniprotkb": "cldn10b; zgc:110625", "gene_names_refseq": "cldn10b; zgc:110625", "protein_names_uniprotkb": "Claudin", "protein_names_refseq": "uncharacterized protein LOC100004456", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "23726886;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC095342.1, CK698110.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505389 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000009.1. On or before Feb 23, 2011 this sequence version replaced NP_001107127.1, NP_001018449.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N6F6;A0AC58GCT3", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity;GO:0160187 paracellular tight junction channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005923 bicellular tight junction", "go_biological_process": "GO:0160184 paracellular transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1QH81-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QHA4-1", "uniprot_id": [ { "id": "F1QHA4_DANRE", "url": "https://www.uniprot.org/uniprot/F1QHA4", "type": "external" } ], "mass": 41408.0, "length": 370, "protein_name": "Formylglycine-generating enzyme", "gene_name": "sumf1", "organism": "Zebrafish", "refseq_name": "formylglycine-generating enzyme isoform X1", "refseq_ac": [ { "id": "XP_005166098", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166098", "type": "external" } ], "gene_names_uniprotkb": "sumf1; zgc:136465", "gene_names_refseq": "sumf1; zgc:136465", "protein_names_uniprotkb": "Formylglycine-generating enzyme; 1.8.3.7; C-alpha-formylglycine-generating enzyme 1; Sulfatase-modifying factor 1", "protein_names_refseq": "formylglycine-generating enzyme isoform X1", "tax_id": 7955, "disease": "mucosulfatidosis (Disease Ontology:DOID:0050441)", "pathway": " (dre:553423); (R-DRE-1663150); (R-DRE-9840310)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "35721514", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Oxidase that catalyzes the conversion of cysteine to 3-oxoalanine on target proteins, using molecular oxygen and an unidentified reducing agent. 3-oxoalanine modification, which is also named formylglycine (fGly), occurs in the maturation of arylsulfatases and some alkaline phosphatases that use the hydrated form of 3-oxoalanine as a catalytic nucleophile. Known substrates include GALNS, ARSA, STS and ARSE., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BDC4", "ec_number_list": [ { "id": "1.13.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.13.-.-", "type": "external" }, { "id": "1.8.3.7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.3.7", "type": "external" }, { "id": "3.1.6.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.1", "type": "external" }, { "id": "3.1.6.18", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.18", "type": "external" } ], "go_molecular_function": "GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0120147 formylglycine-generating oxidase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen", "go_biological_process": "GO:1904888 cranial skeletal system development;GO:0014005 microglia development;GO:0043687 post-translational protein modification;GO:0030203 glycosaminoglycan metabolic process;GO:0061035 regulation of cartilage development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1QHA4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QHE2-1", "uniprot_id": [ { "id": "F1QHE2_DANRE", "url": "https://www.uniprot.org/uniprot/F1QHE2", "type": "external" } ], "mass": 92125.0, "length": 819, "protein_name": "Zinc phosphodiesterase ELAC protein 2", "gene_name": "elac2", "organism": "Zebrafish", "refseq_name": "zinc phosphodiesterase ELAC protein 2", "refseq_ac": [ { "id": "NP_001243133", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243133", "type": "external" } ], "gene_names_uniprotkb": "elac2; im:7145112", "gene_names_refseq": "elac2; im:7145112", "protein_names_uniprotkb": "Zinc phosphodiesterase ELAC protein 2; 3.1.26.11; ElaC homolog protein 2; Ribonuclease Z 2; tRNA 3 endonuclease 2; tRNase Z 2", "protein_names_refseq": "elaC homolog 2; zinc phosphodiesterase ELAC protein 2", "tax_id": 7955, "disease": "combined oxidative phosphorylation deficiency 17 (Disease Ontology:DOID:0111496)", "pathway": " (dre:492652)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "26469318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC131860.1, GDQQ01016973.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On Jun 25, 2025 this sequence version replaced NP_001243133.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P4C7", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0042781 3'-tRNA processing endoribonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0042645 mitochondrial nucleoid", "go_biological_process": "GO:1990180 mitochondrial tRNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1QHE2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QHE9-1", "uniprot_id": [ { "id": "F1QHE9_DANRE", "url": "https://www.uniprot.org/uniprot/F1QHE9", "type": "external" } ], "mass": 24276.0, "length": 217, "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "ndufs7", "organism": "Zebrafish", "refseq_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "refseq_ac": [ { "id": "NP_001186841", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186841", "type": "external" } ], "gene_names_uniprotkb": "ndufs7; fj19d10; im:7149436; wu:fj19d10", "gene_names_refseq": "fj19d10; im:7149436; ndufs7; wu:fj19d10", "protein_names_uniprotkb": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; Complex I-20kD; NADH-ubiquinone oxidoreductase 20 kDa subunit", "protein_names_refseq": "NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "tax_id": 7955, "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037); nuclear type mitochondrial complex I deficiency 3 (Disease Ontology:DOID:0112093); bipolar disorder (Disease Ontology:DOID:3312)", "pathway": " (dre:796997); (R-DRE-611105); (R-DRE-6799198)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "27189481;28252024;33548715;36794678;37070960", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01003002.1, EH455252.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH455252.1, EH542385.1 and JBMGRA010000011.1., [RefSeq]; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NVL4", "ec_number_list": [ { "id": "7.1.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.1.2", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0008137 NADH dehydrogenase (ubiquinone) activity;GO:0048038 quinone binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0045271 respiratory chain complex I", "go_biological_process": "GO:0032981 mitochondrial respiratory chain complex I assembly;GO:0009060 aerobic respiration;GO:0015990 electron transport coupled proton transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F1QHE9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QHF8-1", "uniprot_id": [ { "id": "F1QHF8_DANRE", "url": "https://www.uniprot.org/uniprot/F1QHF8", "type": "external" } ], "mass": 39838.0, "length": 355, "protein_name": "Glucose-6-phosphatase", "gene_name": "g6pc1a.2", "organism": "Zebrafish", "refseq_name": "glucose-6-phosphatase catalytic subunit 1", "refseq_ac": [ { "id": "NP_001157278", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157278", "type": "external" } ], "gene_names_uniprotkb": "g6pc1a.2; g6pca.2; im:6895556; im:7148077; si:ch211-215l11.5", "gene_names_refseq": "g6pc1a.2; g6pca.2; im:6895556; im:7148077; si:ch211-215l11.5", "protein_names_uniprotkb": "Glucose-6-phosphatase; 3.1.3.9", "protein_names_refseq": "glucose-6-phosphatase a, catalytic subunit, tandem duplicate 2; glucose-6-phosphatase a, catalytic, tandem duplicate 2; glucose-6-phosphatase catalytic subunit 1", "tax_id": 7955, "disease": "glycogen storage disease Ia (Disease Ontology:DOID:2749); hepatocellular carcinoma (Disease Ontology:DOID:684); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dre:563180); (R-DRE-70263)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "22297719;24683187;25745818;25999794;26040990;35685883;36202338;36403304;36864841;38805544", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC129224.1, GFIL01011072.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1. On Jun 25, 2025 this sequence version replaced NP_001157278.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production in the terminal step of glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NV27", "ec_number_list": [ { "id": "3.1.3.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.9", "type": "external" } ], "go_molecular_function": "GO:0004346 glucose-6-phosphatase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006094 gluconeogenesis;GO:0048878 chemical homeostasis;GO:0051156 glucose 6-phosphate metabolic process;GO:0061959 response to (R)-carnitine", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QHF8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QHM6-1", "uniprot_id": [ { "id": "F1QHM6_DANRE", "url": "https://www.uniprot.org/uniprot/F1QHM6", "type": "external" } ], "mass": 34099.0, "length": 310, "protein_name": "NAD-dependent protein deacylase", "gene_name": "sirt4", "organism": "Zebrafish", "refseq_name": "NAD-dependent protein lipoamidase sirtuin-4, mitochondrial isoform X1", "refseq_ac": [ { "id": "XP_005166123", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166123", "type": "external" } ], "gene_names_uniprotkb": "sirt4; im:7139453; zgc:103539", "gene_names_refseq": "im:7139453; sirt4; zgc:103539", "protein_names_uniprotkb": "NAD-dependent protein deacylase; 2.3.1.-; Regulatory protein SIR2 homolog", "protein_names_refseq": "NAD-dependent protein lipoamidase sirtuin-4, mitochondrial isoform X1", "tax_id": 7955, "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208)", "pathway": " (dre:791628); (R-DRE-204174); (R-DRE-2151201)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BDH5", "ec_number_list": [ { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "2.3.1.286", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.286", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0070403 NAD+ binding;GO:0004407 histone deacetylase activity;GO:0003950 NAD+ poly-ADP-ribosyltransferase activity;GO:0034979 NAD-dependent protein lysine deacetylase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QHM6-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QHM7-1", "uniprot_id": [ { "id": "ZD23A_DANRE", "url": "https://www.uniprot.org/uniprot/F1QHM7", "type": "external" } ], "mass": 45484.0, "length": 403, "protein_name": "Palmitoyltransferase ZDHHC23-A", "gene_name": "zdhhc23a", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "zdhhc23a; si:ch211-137i24.2", "gene_names_refseq": "", "protein_names_uniprotkb": "Palmitoyltransferase ZDHHC23-A; 2.3.1.225; Zinc finger DHHC domain-containing protein 23-A", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates and be involved in a variety of cellular processes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.225", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.225", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" } ], "go_molecular_function": "GO:0019706 protein-cysteine S-palmitoyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0072659 protein localization to plasma membrane;GO:0006612 protein targeting to membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1QHM7-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QHM9-1", "uniprot_id": [ { "id": "F1QHM9_DANRE", "url": "https://www.uniprot.org/uniprot/F1QHM9", "type": "external" } ], "mass": 60305.0, "length": 519, "protein_name": "Cryptochrome circadian regulator 5 isoform X1", "gene_name": "cry5", "organism": "Zebrafish", "refseq_name": "cryptochrome circadian regulator 5 isoform X1", "refseq_ac": [ { "id": "XP_005155462", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155462", "type": "external" } ], "gene_names_uniprotkb": "cry5; z6-4phr; z64phr", "gene_names_refseq": "cry5; z6-4phr; z64phr", "protein_names_uniprotkb": "Cryptochrome circadian regulator 5 isoform X1", "protein_names_refseq": "cryptochrome circadian regulator 5 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B1I7", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0071949 FAD binding;GO:0003904 deoxyribodipyrimidine photo-lyase activity;GO:0003914 DNA (6-4) photolyase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006281 DNA repair;GO:0032922 circadian regulation of gene expression;GO:0009416 response to light stimulus;GO:0043153 entrainment of circadian clock by photoperiod", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QHM9-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QI36-1", "uniprot_id": [ { "id": "F1QI36_DANRE", "url": "https://www.uniprot.org/uniprot/F1QI36", "type": "external" } ], "mass": 140725.0, "length": 1313, "protein_name": "Sal-like protein 1", "gene_name": "sall1a", "organism": "Zebrafish", "refseq_name": "sal-like protein 1a", "refseq_ac": [ { "id": "NP_001139486", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139486", "type": "external" } ], "gene_names_uniprotkb": "sall1a; cb896spalt; id:ibd5077; sall1; sb:eu809", "gene_names_refseq": "cb896spalt; id:ibd5077; sall1a; sall1; sb:eu809", "protein_names_uniprotkb": "Sal-like protein 1", "protein_names_refseq": "cb896; sal-like 1a; sal-like protein 1a; spa1a; spalt1a", "tax_id": 7955, "disease": "Townes-Brocks syndrome (Disease Ontology:DOID:0050887); middle lobe syndrome (Disease Ontology:DOID:2810); carcinoma (Disease Ontology:DOID:305); renal Wilms' tumor (Disease Ontology:DOID:5176); hepatoblastoma (Disease Ontology:DOID:687); chronic kidney disease (Disease Ontology:DOID:784)", "pathway": " (dre:555721)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12590351;14660549;15133664;17205186;17953490;32709934;36318534;36745553;38286185;38850245", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01020821.1, GFIL01034402.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000007.1. On Mar 24, 2009 this sequence version replaced XP_683406.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Transcriptional repressor involved in organogenesis. Plays an essential role in ureteric bud invasion during kidney development., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7V0N8", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0000792 heterochromatin", "go_biological_process": "GO:0035295 tube development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007507 heart development", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QI36-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QIB5-1", "uniprot_id": [ { "id": "F1QIB5_DANRE", "url": "https://www.uniprot.org/uniprot/F1QIB5", "type": "external" } ], "mass": 45037.0, "length": 394, "protein_name": "Ras-related GTP-binding protein", "gene_name": "rragd", "organism": "Zebrafish", "refseq_name": "ras-related GTP-binding protein D", "refseq_ac": [ { "id": "NP_001092894", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092894", "type": "external" } ], "gene_names_uniprotkb": "rragd; zgc:162165", "gene_names_refseq": "rragd; zgc:162165", "protein_names_uniprotkb": "Ras-related GTP-binding protein", "protein_names_refseq": "ras-related GTP-binding protein D", "tax_id": 7955, "disease": "renal hypomagnesemia 7, with or without dilated cardiomyopathy (Disease Ontology:DOID:0060972)", "pathway": " (dre:570568); (R-DRE-1632852); (R-DRE-165159); (R-DRE-166208); (R-DRE-380972); (R-DRE-5628897); (R-DRE-8943724); (R-DRE-9639288)", "pathway_count": 8, "publication_count": 10, "publication_id_list": "21857967;23469178;26015096;26469318;27189481;28592872;29670865;30402654;37767930;39331021", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01022760.1, GFIL01034083.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476739, SAMEA4476747 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000017.1. On Feb 26, 2016 this sequence version replaced NP_001092894.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade., [UniProtKB, UniProtKB, UniProtKB]; RRAGD variants cause cardiac dysfunction in a zebrafish model., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NDV2", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046982 protein heterodimerization activity;GO:0051020 GTPase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005764 lysosome;GO:0005765 lysosomal membrane", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0010507 negative regulation of autophagy;GO:0009267 cellular response to starvation;GO:0034198 cellular response to amino acid starvation;GO:0071230 cellular response to amino acid stimulus", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QIB5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QIC9-1", "uniprot_id": [ { "id": "F1QIC9_DANRE", "url": "https://www.uniprot.org/uniprot/F1QIC9", "type": "external" } ], "mass": 55856.0, "length": 504, "protein_name": "Nuclear receptor subfamily 1 group D member 2a", "gene_name": "nr1d2a", "organism": "Zebrafish", "refseq_name": "nuclear receptor subfamily 1 group D member 2a", "refseq_ac": [ { "id": "NP_001124064", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001124064", "type": "external" } ], "gene_names_uniprotkb": "nr1d2a; NR1D2-A; Reverbbeta-A; reverbb1", "gene_names_refseq": "NR1D2-A; Reverbbeta-A; nr1d2a; reverbb1", "protein_names_uniprotkb": "Nuclear receptor subfamily 1 group D member 2a", "protein_names_refseq": "Rev-Erb Beta 1; nuclear receptor subfamily 1 group D member 2a", "tax_id": 7955, "disease": "atrioventricular septal defect (Disease Ontology:DOID:0050651)", "pathway": " (dre:402815); (R-DRE-383280)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "11337474;17496157;17997606;22031781;22666345;31905574;32497529;33508534;34925060;36683854", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588718.30274453.1, SRR26395015.316818.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1 and EH436346.1. On Feb 19, 2016 this sequence version replaced NP_001124064.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UZ57;X1WGF5", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0032922 circadian regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QIC9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QIE6-1", "uniprot_id": [ { "id": "F1QIE6_DANRE", "url": "https://www.uniprot.org/uniprot/F1QIE6", "type": "external" } ], "mass": 56870.0, "length": 504, "protein_name": "G protein-activated inward rectifier potassium channel 1", "gene_name": "kcnj19a", "organism": "Zebrafish", "refseq_name": "G protein-activated inward rectifier potassium channel 1 isoform X1", "refseq_ac": [ { "id": "XP_698251", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698251", "type": "external" } ], "gene_names_uniprotkb": "kcnj19a", "gene_names_refseq": "kcnj19a", "protein_names_uniprotkb": "G protein-activated inward rectifier potassium channel 1; Inward rectifier K(+) channel Kir3.1; Potassium channel, inwardly rectifying subfamily J member 3", "protein_names_refseq": "G protein-activated inward rectifier potassium channel 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TFP8", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.2", "type": "external" } ], "go_molecular_function": "GO:0015467 G-protein activated inward rectifier potassium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0034702 monoatomic ion channel complex", "go_biological_process": "GO:0007399 nervous system development;GO:1990573 potassium ion import across plasma membrane;GO:0034220 monoatomic ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QIE6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QJ26-1", "uniprot_id": [ { "id": "F1QJ26_DANRE", "url": "https://www.uniprot.org/uniprot/F1QJ26", "type": "external" } ], "mass": 47246.0, "length": 431, "protein_name": "Zona pellucida sperm-binding protein 4", "gene_name": "zp2.6", "organism": "Zebrafish", "refseq_name": "zona pellucida glycoprotein 2, tandem duplicate 6 precursor", "refseq_ac": [ { "id": "NP_571904", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571904", "type": "external" } ], "gene_names_uniprotkb": "zp2.6; fc33d01; zgc:111913; zgc:111918; zp2.4; zp2c; zp2", "gene_names_refseq": "fc33d01; zgc:111913; zgc:111918; zp2.4; zp2.6; zp2c; zp2", "protein_names_uniprotkb": "Zona pellucida sperm-binding protein 4; Zona pellucida glycoprotein 4; Zona pellucida protein B", "protein_names_refseq": "zona pellucida glycoprotein 2, tandem duplicate 4; zona pellucida glycoprotein 2, tandem duplicate 6 precursor; zona pellucida glycoprotein 2.4; zona pellucida glycoprotein 2.6", "tax_id": 7955, "disease": "", "pathway": " (dre:114440); (R-DRE-2534343)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "19299318;21281742;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC093133.1, SRR26395012.992774.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708832, SAMEA898400 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On Oct 5, 2016 this sequence version replaced NP_571904.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PCA2", "ec_number_list": [], "go_molecular_function": "GO:0035804 structural constituent of egg coat;GO:0032190 acrosin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0035805 egg coat", "go_biological_process": "GO:0007339 binding of sperm to zona pellucida;GO:0060468 prevention of polyspermy", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1QJ26-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QJD4-1", "uniprot_id": [ { "id": "F1QJD4_DANRE", "url": "https://www.uniprot.org/uniprot/F1QJD4", "type": "external" } ], "mass": 110425.0, "length": 988, "protein_name": "receptor protein-tyrosine kinase", "gene_name": "epha4l", "organism": "Zebrafish", "refseq_name": "ephrin type-A receptor 4", "refseq_ac": [ { "id": "XP_687698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687698", "type": "external" } ], "gene_names_uniprotkb": "epha4l", "gene_names_refseq": "epha4l", "protein_names_uniprotkb": "receptor protein-tyrosine kinase; 2.7.10.1", "protein_names_refseq": "ephrin type-A receptor 4", "tax_id": 7955, "disease": "", "pathway": " (dre:30687); (R-DRE-2682334); (R-DRE-3928663); (R-DRE-3928665)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_687698.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TAS1", "ec_number_list": [ { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0005005 transmembrane-ephrin receptor activity", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0030425 dendrite", "go_biological_process": "GO:0007155 cell adhesion;GO:0048013 ephrin receptor signaling pathway;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QJD4-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QJE5-1", "uniprot_id": [ { "id": "F1QJE5_DANRE", "url": "https://www.uniprot.org/uniprot/F1QJE5", "type": "external" } ], "mass": 57697.0, "length": 537, "protein_name": "Protein phosphatase 1G", "gene_name": "ppm1g", "organism": "Zebrafish", "refseq_name": "protein phosphatase 1G", "refseq_ac": [ { "id": "NP_958896", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_958896", "type": "external" } ], "gene_names_uniprotkb": "ppm1g; cb167; wu:fb37b10; wu:fe01e01", "gene_names_refseq": "cb167; ppm1g; wu:fb37b10; wu:fe01e01", "protein_names_uniprotkb": "Protein phosphatase 1G; 3.1.3.16", "protein_names_refseq": "protein phosphatase 1G", "tax_id": 7955, "disease": "schizophrenia (Disease Ontology:DOID:5419)", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "19581931;23723158", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01003911.1, GDQQ01008319.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On or before Jul 28, 2025 this sequence version replaced XP_005169569.1, NP_958896.1., [RefSeq]; Dab2 stabilizes Axin and attenuates Wnt/beta-catenin signaling by preventing PP1 from binding Axin, [RefSeq, PubMed]; Nuclear phosphatase PPM1G in cellular survival and neural development., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BGW3", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0016020 membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0007417 central nervous system development;GO:0051726 regulation of cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1QJE5-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QJK9-1", "uniprot_id": [ { "id": "F1QJK9_DANRE", "url": "https://www.uniprot.org/uniprot/F1QJK9", "type": "external" } ], "mass": 91223.0, "length": 810, "protein_name": "protein-lysine 6-oxidase", "gene_name": "loxl4", "organism": "Zebrafish", "refseq_name": "lysyl oxidase homolog 4", "refseq_ac": [ { "id": "XP_002664258", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664258", "type": "external" } ], "gene_names_uniprotkb": "loxl4", "gene_names_refseq": "loxl4", "protein_names_uniprotkb": "protein-lysine 6-oxidase; 1.4.3.13", "protein_names_refseq": "lysyl oxidase homolog 4", "tax_id": 7955, "disease": "", "pathway": " (R-DRE-2243919)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_002664258.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RKL6;A0AC58H315", "ec_number_list": [ { "id": "1.4.3.13", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.13", "type": "external" }, { "id": "1.4.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" } ], "go_molecular_function": "GO:0005507 copper ion binding;GO:0004720 protein-lysine 6-oxidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0031012 extracellular matrix", "go_biological_process": "GO:0030199 collagen fibril organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QJK9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QJL3-1", "uniprot_id": [ { "id": "F1QJL3_DANRE", "url": "https://www.uniprot.org/uniprot/F1QJL3", "type": "external" } ], "mass": 74487.0, "length": 656, "protein_name": "Sulfhydryl oxidase", "gene_name": "qsox2", "organism": "Zebrafish", "refseq_name": "sulfhydryl oxidase 2", "refseq_ac": [ { "id": "XP_009300239", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009300239", "type": "external" } ], "gene_names_uniprotkb": "qsox2", "gene_names_refseq": "qsox2", "protein_names_uniprotkb": "Sulfhydryl oxidase; 1.8.3.2", "protein_names_refseq": "sulfhydryl oxidase 2", "tax_id": 7955, "disease": "", "pathway": " (dre:559603)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3ASX7", "ec_number_list": [ { "id": "1.8.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.3.2", "type": "external" } ], "go_molecular_function": "GO:0016971 flavin-dependent sulfhydryl oxidase activity;GO:0003756 protein disulfide isomerase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005615 extracellular space", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QJL3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QJY8-1", "uniprot_id": [ { "id": "F1QJY8_DANRE", "url": "https://www.uniprot.org/uniprot/F1QJY8", "type": "external" } ], "mass": 112663.0, "length": 1003, "protein_name": "Condensin complex subunit 3", "gene_name": "ncapg", "organism": "Zebrafish", "refseq_name": "condensin complex subunit 3", "refseq_ac": [ { "id": "NP_001243134", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243134", "type": "external" } ], "gene_names_uniprotkb": "ncapg; im:7149538; im:7151414; si:dkeyp-26a9.1", "gene_names_refseq": "im:7149538; im:7151414; ncapg; si:dkeyp-26a9.1", "protein_names_uniprotkb": "Condensin complex subunit 3", "protein_names_refseq": "chromosome condensation protein G; condensin complex subunit 3", "tax_id": 7955, "disease": "", "pathway": " (R-DRE-2514853)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "19586528;24198278;27189481;35942692", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01027696.1, GDQH01009399.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505376 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Jun 25, 2025 this sequence version replaced NP_001243134.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3E1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000793 condensed chromosome;GO:0000796 condensin complex", "go_biological_process": "GO:0051301 cell division;GO:0007076 mitotic chromosome condensation;GO:0000070 mitotic sister chromatid segregation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F1QJY8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QK15-1", "uniprot_id": [ { "id": "F1QK15_DANRE", "url": "https://www.uniprot.org/uniprot/F1QK15", "type": "external" } ], "mass": 320410.0, "length": 2902, "protein_name": "Neural-cadherin", "gene_name": "si:ch211-186j3.6", "organism": "Zebrafish", "refseq_name": "neural-cadherin", "refseq_ac": [ { "id": "XP_001920988", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001920988", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-186j3.6", "gene_names_refseq": "si:ch211-186j3.6", "protein_names_uniprotkb": "Neural-cadherin", "protein_names_refseq": "neural-cadherin", "tax_id": 7955, "disease": "", "pathway": " (dre:556807)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001920988.2. COMPLETENESS: full length., [RefSeq]; Cadherins are calcium-dependent cell adhesion proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QQU9", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005911 cell-cell junction", "go_biological_process": "GO:0098609 cell-cell adhesion;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0002009 morphogenesis of an epithelium;GO:0045216 cell-cell junction organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QK15-1", "record_type": "protein", "filter_code": "0000000.0000001.001000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QKB5-1", "uniprot_id": [ { "id": "F1QKB5_DANRE", "url": "https://www.uniprot.org/uniprot/F1QKB5", "type": "external" } ], "mass": 104746.0, "length": 950, "protein_name": "Inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X1", "gene_name": "ror1", "organism": "Zebrafish", "refseq_name": "inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X1", "refseq_ac": [ { "id": "XP_005165942", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165942", "type": "external" } ], "gene_names_uniprotkb": "ror1", "gene_names_refseq": "ror1", "protein_names_uniprotkb": "Inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X1", "protein_names_refseq": "inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X1", "tax_id": 7955, "disease": "autosomal recessive nonsyndromic deafness 108 (Disease Ontology:DOID:0080263)", "pathway": " (dre:568282); (R-DRE-5140745)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BDD8;F1QBL8", "ec_number_list": [], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0017147 Wnt-protein binding;GO:0038023 signaling receptor activity;GO:0016301 kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0043235 receptor complex", "go_biological_process": "GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0016055 Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QKB5-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QKC4-1", "uniprot_id": [ { "id": "F1QKC4_DANRE", "url": "https://www.uniprot.org/uniprot/F1QKC4", "type": "external" } ], "mass": 49337.0, "length": 435, "protein_name": "Gamma-aminobutyric acid receptor subunit alpha-6a isoform X1", "gene_name": "gabra6a", "organism": "Zebrafish", "refseq_name": "gamma-aminobutyric acid receptor subunit alpha-6a isoform X1", "refseq_ac": [ { "id": "XP_005173169", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173169", "type": "external" } ], "gene_names_uniprotkb": "gabra6a; si:dkey-217k23.1; zgc:73148", "gene_names_refseq": "gabra6a; si:dkey-217k23.1; zgc:73148", "protein_names_uniprotkb": "Gamma-aminobutyric acid receptor subunit alpha-6a isoform X1", "protein_names_refseq": "gamma-aminobutyric acid receptor subunit alpha-6a isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BKE0", "ec_number_list": [], "go_molecular_function": "GO:0004890 GABA-A receptor activity;GO:0022851 GABA-gated chloride ion channel activity", "go_cellular_component": "GO:0045211 postsynaptic membrane;GO:0098794 postsynapse;GO:0034707 chloride channel complex;GO:0032590 dendrite membrane;GO:1902711 GABA-A receptor complex", "go_biological_process": "GO:0007214 gamma-aminobutyric acid signaling pathway;GO:1902476 chloride transmembrane transport;GO:0051932 synaptic transmission, GABAergic;GO:1904862 inhibitory synapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QKC4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QKM3-1", "uniprot_id": [ { "id": "F1QKM3_DANRE", "url": "https://www.uniprot.org/uniprot/F1QKM3", "type": "external" } ], "mass": 75034.0, "length": 663, "protein_name": "1.13.11.12; Uncharacterized protein LOC767741", "gene_name": "zgc:152891; zgc:153926", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC767741", "refseq_ac": [ { "id": "NP_001070178", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070178", "type": "external" } ], "gene_names_uniprotkb": "zgc:152891; zgc:153926; alox12b; wu:fi89d03; zgc:152891; zgc:153926", "gene_names_refseq": "alox12b; wu:fi89d03; zgc:152891; zgc:153926", "protein_names_uniprotkb": "1.13.11.12; Uncharacterized protein LOC767741", "protein_names_refseq": "ALOX4b; uncharacterized protein LOC767741", "tax_id": 7955, "disease": "autosomal recessive congenital ichthyosis 1 (Disease Ontology:DOID:0060656); autosomal recessive congenital ichthyosis 2 (Disease Ontology:DOID:0060710); autosomal recessive congenital ichthyosis 3 (Disease Ontology:DOID:0060711)", "pathway": " (dre:767741); (R-DRE-2142712); (R-DRE-2142770)", "pathway_count": 3, "publication_count": 7, "publication_id_list": "26456699;26469318;27189481;27219276;31662245;32296464;38605226", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124493.1, BC124599.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from BC124493.1. On Oct 8, 2011 this sequence version replaced NP_001070178.1. Sequence Note: This RefSeq record was created from a transcript of a different strain than the reference genome strain because no single transcript from the reference strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N9Y2", "ec_number_list": [ { "id": "1.13.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:1.13.11.12", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0016165 linoleate 13S-lipoxygenase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0034440 lipid oxidation;GO:0019372 lipoxygenase pathway;GO:0019369 arachidonate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "F1QKM3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QKS8-1", "uniprot_id": [ { "id": "F1QKS8_DANRE", "url": "https://www.uniprot.org/uniprot/F1QKS8", "type": "external" } ], "mass": 17365.0, "length": 156, "protein_name": "Arachidonate 5-lipoxygenase-activating protein", "gene_name": "alox5ap", "organism": "Zebrafish", "refseq_name": "arachidonate 5-lipoxygenase-activating protein", "refseq_ac": [ { "id": "NP_956355", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956355", "type": "external" } ], "gene_names_uniprotkb": "alox5ap; wu:fj65d02; zgc:63982", "gene_names_refseq": "alox5ap; wu:fj65d02; zgc:63982", "protein_names_uniprotkb": "Arachidonate 5-lipoxygenase-activating protein", "protein_names_refseq": "Flap; arachidonate 5-lipoxygenase-activating protein", "tax_id": 7955, "disease": "stroke (Disease Ontology:DOID:0051061); common cold (Disease Ontology:DOID:10459); breast cancer (Disease Ontology:DOID:1612); cerebral palsy (Disease Ontology:DOID:1969); arteriosclerosis (Disease Ontology:DOID:2349); asthma (Disease Ontology:DOID:2841); coronary artery disease (Disease Ontology:DOID:3393); brain infarction (Disease Ontology:DOID:3454); cerebral infarction (Disease Ontology:DOID:3526); kidney disease (Disease Ontology:DOID:557); myocardial infarction (Disease Ontology:DOID:5844); pulmonary hypertension (Disease Ontology:DOID:6432); neuroblastoma (Disease Ontology:DOID:769); obesity (Disease Ontology:DOID:9970)", "pathway": " (R-DRE-2142688); (R-DRE-2142691); (R-DRE-2142700)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "19389629;20424185;21687630;25461745;25573385;27219276;30765415;31072958", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC053181.1, GFIL01000939.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505384, SAMEA4476771 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000010.1. On Jun 23, 2025 this sequence version replaced NP_956355.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 14, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PDY6", "ec_number_list": [], "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0004464 leukotriene-C4 synthase activity;GO:0008047 enzyme activator activity;GO:0004602 glutathione peroxidase activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005783 endoplasmic reticulum;GO:0031965 nuclear membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0019370 leukotriene biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "F1QKS8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QL10-1", "uniprot_id": [ { "id": "F1QL10_DANRE", "url": "https://www.uniprot.org/uniprot/F1QL10", "type": "external" } ], "mass": 40651.0, "length": 369, "protein_name": "CCN family member 1", "gene_name": "ccn1", "organism": "Zebrafish", "refseq_name": "CCN family member 1 precursor", "refseq_ac": [ { "id": "NP_001001826", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001826", "type": "external" } ], "gene_names_uniprotkb": "ccn1; cyr61; zCyr61-c23; zgc:85866", "gene_names_refseq": "ccn1; cyr61; zCyr61-c23; zgc:85866", "protein_names_uniprotkb": "CCN family member 1; Cellular communication network factor 1; Protein CYR61", "protein_names_refseq": "CCN family member 1 precursor; cysteine-rich, angiogenic inducer, 61", "tax_id": 7955, "disease": "atrioventricular septal defect (Disease Ontology:DOID:0050651); peripheral artery disease (Disease Ontology:DOID:0050830); atrial heart septal defect 1 (Disease Ontology:DOID:0110106); proliferative diabetic retinopathy (Disease Ontology:DOID:13207); capillary hemangioma (Disease Ontology:DOID:2725); high grade glioma (Disease Ontology:DOID:3070); congestive heart failure (Disease Ontology:DOID:6000); rheumatoid arthritis (Disease Ontology:DOID:7148); multiple myeloma (Disease Ontology:DOID:9538)", "pathway": " (dre:403033); (R-DRE-381426); (R-DRE-8957275)", "pathway_count": 3, "publication_count": 10, "publication_id_list": "19801676;20503371;21887364;25313964;26209646;34581723;35876586;37142828;38444829;38960037", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC067668.1, GDQH01014801.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Jun 25, 2025 this sequence version replaced NP_001001826.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1MZN6", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0008201 heparin binding;GO:0019838 growth factor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0007155 cell adhesion;GO:0007165 signal transduction;GO:0030335 positive regulation of cell migration;GO:0045597 positive regulation of cell differentiation;GO:0051240 positive regulation of multicellular organismal process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QL10-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QL21-1", "uniprot_id": [ { "id": "F1QL21_DANRE", "url": "https://www.uniprot.org/uniprot/F1QL21", "type": "external" } ], "mass": 45564.0, "length": 400, "protein_name": "Gap junction protein", "gene_name": "gja5a", "organism": "Zebrafish", "refseq_name": "gap junction protein, alpha 5a isoform X1", "refseq_ac": [ { "id": "XP_005167744", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167744", "type": "external" } ], "gene_names_uniprotkb": "gja5a; cx45.6; zgc:195347; zgc:195362", "gene_names_refseq": "cx45.6; gja5a; zgc:195347; zgc:195362", "protein_names_uniprotkb": "Gap junction protein", "protein_names_refseq": "gap junction protein, alpha 5a isoform X1", "tax_id": 7955, "disease": "familial atrial fibrillation (Disease Ontology:DOID:0050650); atrial fibrillation (Disease Ontology:DOID:0060224); overactive bladder syndrome (Disease Ontology:DOID:0070355); atrial standstill 1 (Disease Ontology:DOID:0080662); hypertension (Disease Ontology:DOID:10763); renovascular hypertension (Disease Ontology:DOID:1591); glomerulonephritis (Disease Ontology:DOID:2921); ureteral obstruction (Disease Ontology:DOID:5199); myocardial infarction (Disease Ontology:DOID:5844); tetralogy of Fallot (Disease Ontology:DOID:6419); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:404729)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14648847;14704230;16337772;17338632;18068130;30611731;30809154;31666235;35325106;36889448", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9QJK2;A0AC58GDS2;A0AC58GDV0", "ec_number_list": [], "go_molecular_function": "GO:0086076 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling;GO:0005243 gap junction channel activity", "go_cellular_component": "GO:0005922 connexin complex", "go_biological_process": "GO:0007267 cell-cell signaling;GO:0007507 heart development;GO:0086044 atrial cardiac muscle cell to AV node cell communication by electrical coupling;GO:0007154 cell communication", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QL21-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QLC3-1", "uniprot_id": [ { "id": "F1QLC3_DANRE", "url": "https://www.uniprot.org/uniprot/F1QLC3", "type": "external" } ], "mass": 56932.0, "length": 504, "protein_name": "coagulation factor Xa", "gene_name": "f10", "organism": "Zebrafish", "refseq_name": "coagulation factor X", "refseq_ac": [ { "id": "NP_958870", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_958870", "type": "external" } ], "gene_names_uniprotkb": "f10; fi12c10; wu:fi12c10", "gene_names_refseq": "f10; fi12c10; wu:fi12c10", "protein_names_uniprotkb": "coagulation factor Xa; 3.4.21.6", "protein_names_refseq": "coagulation factor 10; coagulation factor X", "tax_id": 7955, "disease": "breast cancer (Disease Ontology:DOID:1612); factor X deficiency (Disease Ontology:DOID:2222)", "pathway": " (R-DRE-159763); (R-DRE-159782); (R-DRE-9769735); (R-DRE-9769739); (R-DRE-9769743)", "pathway_count": 5, "publication_count": 10, "publication_id_list": "19200601;22047996;22438865;26469318;27189481;31887585;33134781;34185526;38104724;39358551", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC056804.1, GFIL01009958.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On or before Jun 9, 2015 this sequence version replaced XP_005168043.2, NP_958870.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PG13;A0AC58JTH6", "ec_number_list": [ { "id": "3.4.21.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.5", "type": "external" }, { "id": "3.4.21.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.6", "type": "external" } ], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0007596 blood coagulation;GO:0007599 hemostasis;GO:0044469 venom-mediated blood coagulation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QLC3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QM42-1", "uniprot_id": [ { "id": "F1QM42_DANRE", "url": "https://www.uniprot.org/uniprot/F1QM42", "type": "external" } ], "mass": 99055.0, "length": 890, "protein_name": "Cytoplasmic aconitate hydratase", "gene_name": "aco1", "organism": "Zebrafish", "refseq_name": "cytoplasmic aconitate hydratase isoform X1", "refseq_ac": [ { "id": "XP_005172430", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005172430", "type": "external" } ], "gene_names_uniprotkb": "aco1; irp1; wu:fo75b03", "gene_names_refseq": "aco1; irp1; wu:fo75b03", "protein_names_uniprotkb": "Cytoplasmic aconitate hydratase; 4.2.1.3; Citrate hydro-lyase", "protein_names_refseq": "cytoplasmic aconitate hydratase isoform X1", "tax_id": 7955, "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); porphyria (Disease Ontology:DOID:13268); duodenal ulcer (Disease Ontology:DOID:1724)", "pathway": " (dre:568448); (R-DRE-389542); (R-DRE-917937)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BJL9", "ec_number_list": [ { "id": "4.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.3", "type": "external" } ], "go_molecular_function": "GO:0003994 aconitate hydratase activity;GO:0046872 metal ion binding;GO:0051538 3 iron, 4 sulfur cluster binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0030350 iron-responsive element binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006101 citrate metabolic process;GO:0006879 intracellular iron ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QM42-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QMF9-1", "uniprot_id": [ { "id": "F1QMF9_DANRE", "url": "https://www.uniprot.org/uniprot/F1QMF9", "type": "external" } ], "mass": 10163.0, "length": 89, "protein_name": "Ubiquitin-like protein NEDD8", "gene_name": "nedd8", "organism": "Zebrafish", "refseq_name": "NEDD8", "refseq_ac": [ { "id": "NP_958478", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_958478", "type": "external" } ], "gene_names_uniprotkb": "nedd8; si:zc14a17.5; ubiquitin", "gene_names_refseq": "nedd8; si:zc14a17.5; ubiquitin", "protein_names_uniprotkb": "Ubiquitin-like protein NEDD8; Neddylin", "protein_names_refseq": "NEDD8; neural precursor cell expressed, developmentally down-regulated 8", "tax_id": 7955, "disease": "alcohol-associated liver disease (Disease Ontology:DOID:0070658); Parkinson's disease (Disease Ontology:DOID:14330); malignant astrocytoma (Disease Ontology:DOID:3069)", "pathway": " (dre:368667); (R-DRE-2173789); (R-DRE-5689603); (R-DRE-8856825); (R-DRE-8951664); (R-DRE-917937)", "pathway_count": 6, "publication_count": 7, "publication_id_list": "19221799;26469318;28252024;31293590;32978241;35134494;38960037", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH443336.1, DT318340.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH443336.1 and EH507246.1. On Jul 19, 2011 this sequence version replaced NP_958478.1., [RefSeq]; NEDD8 enhances Hippo signaling by mediating YAP1 neddylation., [RefSeq, PubMed]; Neddylation Facilitates the Antiviral Response in Zebrafish. Publication Status: Online-Only, [RefSeq, PubMed]; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis via its conjugation to a limited number of cellular proteins, such as cullins or p53/TP53. Attachment of NEDD8 to cullins is critical for the recruitment of E2 to the cullin-RING-based E3 ubiquitin-protein ligase complex, thus facilitating polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. Attachment of NEDD8 to p53/TP53 inhibits p53/TP53 transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PFY0", "ec_number_list": [], "go_molecular_function": "GO:0031386 protein tag activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0051607 defense response to virus;GO:0030162 regulation of proteolysis;GO:0019941 modification-dependent protein catabolic process;GO:0045116 protein neddylation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "F1QMF9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QMN8-1", "uniprot_id": [ { "id": "F1QMN8_DANRE", "url": "https://www.uniprot.org/uniprot/F1QMN8", "type": "external" } ], "mass": 114284.0, "length": 989, "protein_name": "3.2.2.6; Toll-like receptor 21 precursor", "gene_name": "tlr21", "organism": "Zebrafish", "refseq_name": "toll-like receptor 21 precursor", "refseq_ac": [ { "id": "NP_001186264", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186264", "type": "external" } ], "gene_names_uniprotkb": "tlr21; TLR21.1", "gene_names_refseq": "TLR21.1; tlr21", "protein_names_uniprotkb": "3.2.2.6; Toll-like receptor 21 precursor", "protein_names_refseq": "TIR21.1; toll-like receptor 21 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:402884)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14687933;14687934;16552074;18248169;22729906;24327191;26083432;27189481;32554491;34130754", "class_list": "", "function": "##Evidence-Data-START## Transcript is intronless :: GDQQ01054551.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Jun 25, 2025 this sequence version replaced NP_001186264.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NWC7", "ec_number_list": [], "go_molecular_function": "GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane", "go_biological_process": "GO:0002221 pattern recognition receptor signaling pathway;GO:0006954 inflammatory response;GO:0019731 antibacterial humoral response;GO:0045087 innate immune response;GO:0002224 toll-like receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QMN8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QMV3-1", "uniprot_id": [ { "id": "TPC6B_DANRE", "url": "https://www.uniprot.org/uniprot/F1QMV3", "type": "external" } ], "mass": 17894.0, "length": 157, "protein_name": "Trafficking protein particle complex subunit 6b", "gene_name": "trappc6b", "organism": "Zebrafish", "refseq_name": "trafficking protein particle complex subunit 6b", "refseq_ac": [ { "id": "NP_001006029", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006029", "type": "external" } ], "gene_names_uniprotkb": "trappc6b", "gene_names_refseq": "trappc6b; zgc:103464", "protein_names_uniprotkb": "Trafficking protein particle complex subunit 6b; TRAPP complex subunit 6B", "protein_names_refseq": "TRAPP complex subunit 6B; trafficking protein particle complex 6b; trafficking protein particle complex subunit 6b", "tax_id": 7955, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888); neurodevelopmental disorder with microcephaly, epilepsy, and brain atrophy (Disease Ontology:DOID:0060934)", "pathway": " (dre:450008); (R-DRE-204005); (R-DRE-8876198)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "23594743;28626029", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC083391.1, EH450189.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083391.1., [RefSeq]; Component of a transport protein particle (TRAPP) complex that may function in specific stages of inter-organelle traffic. Specifically involved in the early development of neural circuitry, likely by controlling the frequency and amplitude of intracellular calcium transients implicated in the regulation of neuron differentiation and survival., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5XJB3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005801 cis-Golgi network;GO:0005802 trans-Golgi network;GO:0030008 TRAPP complex", "go_biological_process": "GO:0007399 nervous system development;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1QMV3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QMY1-1", "uniprot_id": [ { "id": "DYT2B_DANRE", "url": "https://www.uniprot.org/uniprot/F1QMY1", "type": "external" } ], "mass": 17172.0, "length": 150, "protein_name": "Dynein light chain Tctex-type protein 2B", "gene_name": "dynlt2b", "organism": "Zebrafish", "refseq_name": "dynein light chain Tctex-type protein 2B", "refseq_ac": [ { "id": "NP_001410688", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410688", "type": "external" } ], "gene_names_uniprotkb": "dynlt2b; si:ch211-276k2.4; tctex1d2", "gene_names_refseq": "dynlt2b; si:ch211-276k2.4; tctex1d2", "protein_names_uniprotkb": "Dynein light chain Tctex-type protein 2B; Tctex1 domain-containing protein 2", "protein_names_refseq": "Tctex1 domain containing 2; dynein light chain Tctex-type protein 2B; tctex1 domain-containing protein 2", "tax_id": 7955, "disease": "asphyxiating thoracic dystrophy (Disease Ontology:DOID:0050592); ciliopathy (Disease Ontology:DOID:0060340); spermatogenic failure (Disease Ontology:DOID:0111910)", "pathway": " (dre:553323)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "18335061;23594743;26044572", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH467257.1, GFIL01040574.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from GFIL01040574.1, JBMGRA010000022.1, BF717675.1, EX464680.1, EH530940.1 and EH467257.1. On Aug 14, 2023 this sequence version replaced XP_685487.3., [RefSeq]; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system (By similarity). Required for proper retrograde ciliary transport (PubMed:26044572)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0045505 dynein intermediate chain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005929 cilium;GO:0005868 cytoplasmic dynein complex;GO:0120293 dynein axonemal particle", "go_biological_process": "GO:0007018 microtubule-based movement;GO:0035721 intraciliary retrograde transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1QMY1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QMZ0-1", "uniprot_id": [ { "id": "F1QMZ0_DANRE", "url": "https://www.uniprot.org/uniprot/F1QMZ0", "type": "external" } ], "mass": 47250.0, "length": 431, "protein_name": "Zona pellucida sperm-binding protein 4", "gene_name": "zp2.3", "organism": "Zebrafish", "refseq_name": "zona pellucida sperm-binding protein 2.3 precursor", "refseq_ac": [ { "id": "NP_571903", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571903", "type": "external" } ], "gene_names_uniprotkb": "zp2.3; zp2b; zp2; zpb2a-1", "gene_names_refseq": "zp2.3; zp2b; zp2; zpb2a-1", "protein_names_uniprotkb": "Zona pellucida sperm-binding protein 4; Zona pellucida glycoprotein 4; Zona pellucida protein B", "protein_names_refseq": "zona pellucida glycoprotein 2.3; zona pellucida sperm-binding protein 2.3 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:114439); (R-DRE-2534343)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "19299318;27189481;29307115;30364302", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC125823.1, GFIL01015658.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708832, SAMEA898399 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On Oct 9, 2016 this sequence version replaced NP_571903.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P714", "ec_number_list": [], "go_molecular_function": "GO:0035804 structural constituent of egg coat;GO:0032190 acrosin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0035805 egg coat", "go_biological_process": "GO:0007339 binding of sperm to zona pellucida;GO:0060468 prevention of polyspermy", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F1QMZ0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QMZ9-1", "uniprot_id": [ { "id": "F1QMZ9_DANRE", "url": "https://www.uniprot.org/uniprot/F1QMZ9", "type": "external" } ], "mass": 178743.0, "length": 1594, "protein_name": "ATP-binding cassette sub-family C member 8 isoform X1", "gene_name": "abcc8", "organism": "Zebrafish", "refseq_name": "ATP-binding cassette sub-family C member 8 isoform X1", "refseq_ac": [ { "id": "XP_005170744", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170744", "type": "external" } ], "gene_names_uniprotkb": "abcc8; sur1", "gene_names_refseq": "abcc8; sur1", "protein_names_uniprotkb": "ATP-binding cassette sub-family C member 8 isoform X1", "protein_names_refseq": "ATP-binding cassette sub-family C member 8 isoform X1", "tax_id": 7955, "disease": "stroke (Disease Ontology:DOID:0051061); transient neonatal diabetes mellitus (Disease Ontology:DOID:0060334); permanent neonatal diabetes mellitus (Disease Ontology:DOID:0060639); transient neonatal diabetes mellitus 2 (Disease Ontology:DOID:0061174); familial hyperinsulinemic hypoglycemia 1 (Disease Ontology:DOID:0070219); leucine-sensitive hypoglycemia of infancy (Disease Ontology:DOID:0112262); hypertension (Disease Ontology:DOID:10763); hyperinsulinemic hypoglycemia (Disease Ontology:DOID:13317); hyperinsulinism (Disease Ontology:DOID:2018); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dre:553281); (R-DRE-1296025); (R-DRE-422356)", "pathway_count": 3, "publication_count": 10, "publication_id_list": "16124856;16317080;16631343;24836561;26047617;28694436;30679186;34820842;36458573;38575153", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BI16", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0008281 sulfonylurea receptor activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:0055085 transmembrane transport;GO:0071333 cellular response to glucose stimulus;GO:0033198 response to ATP;GO:0071805 potassium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QMZ9-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QN56-1", "uniprot_id": [ { "id": "F1QN56_DANRE", "url": "https://www.uniprot.org/uniprot/F1QN56", "type": "external" } ], "mass": 81101.0, "length": 709, "protein_name": "Transient receptor potential cation channel subfamily V member 6 isoform X1", "gene_name": "trpv6", "organism": "Zebrafish", "refseq_name": "transient receptor potential cation channel subfamily V member 6 isoform X1", "refseq_ac": [ { "id": "XP_005173525", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173525", "type": "external" } ], "gene_names_uniprotkb": "trpv6; ecac; trpv5-6", "gene_names_refseq": "ecac; trpv5-6; trpv6", "protein_names_uniprotkb": "Transient receptor potential cation channel subfamily V member 6 isoform X1", "protein_names_refseq": "transient receptor potential cation channel subfamily V member 6 isoform X1", "tax_id": 7955, "disease": "pre-eclampsia (Disease Ontology:DOID:10591); gestational diabetes (Disease Ontology:DOID:11714); hyperparathyroidism (Disease Ontology:DOID:13543)", "pathway": " (R-DRE-3295583)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BKQ8;A0AC58HEV6", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.2", "type": "external" } ], "go_molecular_function": "GO:0005262 calcium channel activity;GO:0005516 calmodulin binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0051592 response to calcium ion;GO:0045893 positive regulation of DNA-templated transcription;GO:0070317 negative regulation of G0 to G1 transition;GO:0055074 calcium ion homeostasis;GO:0070509 calcium ion import", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QN56-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QN74-1", "uniprot_id": [ { "id": "ZMY10_DANRE", "url": "https://www.uniprot.org/uniprot/F1QN74", "type": "external" } ], "mass": 51635.0, "length": 448, "protein_name": "Zinc finger MYND domain-containing protein 10", "gene_name": "zmynd10", "organism": "Zebrafish", "refseq_name": "zinc finger MYND domain-containing protein 10", "refseq_ac": [ { "id": "NP_956691", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956691", "type": "external" } ], "gene_names_uniprotkb": "zmynd10; zgc:63660", "gene_names_refseq": "zgc:63660; zmynd10", "protein_names_uniprotkb": "Zinc finger MYND domain-containing protein 10", "protein_names_refseq": "zinc finger MYND domain-containing protein 10", "tax_id": 7955, "disease": "idiopathic scoliosis (Disease Ontology:DOID:0060250); primary ciliary dyskinesia 22 (Disease Ontology:DOID:0110597); sensorineural hearing loss (Disease Ontology:DOID:10003); primary ciliary dyskinesia (Disease Ontology:DOID:9562)", "pathway": " (dre:393368)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;23891469", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC054130.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN06350654 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC054130.1., [RefSeq]; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility (By similarity). May act by indirectly regulating transcription of dynein proteins (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7SZ57", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016324 apical plasma membrane;GO:0034451 centriolar satellite;GO:0120293 dynein axonemal particle", "go_biological_process": "GO:0044458 motile cilium assembly;GO:0036158 outer dynein arm assembly;GO:1905505 positive regulation of motile cilium assembly;GO:0036159 inner dynein arm assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1QN74-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QNA7-1", "uniprot_id": [ { "id": "F1QNA7_DANRE", "url": "https://www.uniprot.org/uniprot/F1QNA7", "type": "external" } ], "mass": 144128.0, "length": 1258, "protein_name": "Cohesin subunit SA", "gene_name": "stag1a", "organism": "Zebrafish", "refseq_name": "cohesin subunit SA-1a", "refseq_ac": [ { "id": "NP_001349269", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001349269", "type": "external" } ], "gene_names_uniprotkb": "stag1a; si:dkey-223d7.4; wu:fc28h03", "gene_names_refseq": "si:dkey-223d7.4; stag1a; wu:fc28h03", "protein_names_uniprotkb": "Cohesin subunit SA; SCC3 homolog; Stromal antigen", "protein_names_refseq": "cohesin subunit SA-1a; stag1; stromal antigen 1a", "tax_id": 7955, "disease": "autosomal dominant intellectual developmental disorder 47 (Disease Ontology:DOID:0080238)", "pathway": " (dre:564533); (R-DRE-2467813); (R-DRE-2468052); (R-DRE-2470946); (R-DRE-2500257); (R-DRE-3108214)", "pathway_count": 6, "publication_count": 6, "publication_id_list": "26469318;27189481;28985365;30017463;33365313;38975838", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588727.1735624.1, SRR32588724.1146385.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505393, SAMEA4476732 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On Jun 5, 2019 this sequence version replaced XP_692954.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7T7W9", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000775 chromosome, centromeric region;GO:0000785 chromatin;GO:0008278 cohesin complex", "go_biological_process": "GO:1901532 regulation of hematopoietic progenitor cell differentiation;GO:0007059 chromosome segregation;GO:0051301 cell division;GO:0007062 sister chromatid cohesion;GO:2001212 regulation of vasculogenesis", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F1QNA7-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QNG0-1", "uniprot_id": [ { "id": "F1QNG0_DANRE", "url": "https://www.uniprot.org/uniprot/F1QNG0", "type": "external" } ], "mass": 118680.0, "length": 1045, "protein_name": "[histone H3]-trimethyl-L-lysine(9) demethylase", "gene_name": "kdm4ab", "organism": "Zebrafish", "refseq_name": "lysine-specific demethylase 4A", "refseq_ac": [ { "id": "XP_001339664", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001339664", "type": "external" } ], "gene_names_uniprotkb": "kdm4ab", "gene_names_refseq": "kdm4ab", "protein_names_uniprotkb": "[histone H3]-trimethyl-L-lysine(9) demethylase; 1.14.11.66", "protein_names_refseq": "lysine-specific demethylase 4A", "tax_id": 7955, "disease": "prostate cancer (Disease Ontology:DOID:10283); urinary bladder cancer (Disease Ontology:DOID:11054); lung cancer (Disease Ontology:DOID:1324); breast cancer (Disease Ontology:DOID:1612); stomach carcinoma (Disease Ontology:DOID:5517); alopecia areata (Disease Ontology:DOID:986)", "pathway": " (dre:334347); (R-DRE-3214842); (R-DRE-5693565)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_001339664.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PZC5", "ec_number_list": [ { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.14.11.66", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.66", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" } ], "go_molecular_function": "GO:0051864 histone H3K36 demethylase activity;GO:0008270 zinc ion binding;GO:0032454 histone H3K9 demethylase activity;GO:0140684 histone H3K9me2/H3K9me3 demethylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0048514 blood vessel morphogenesis;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QNG0-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QNG2-1", "uniprot_id": [ { "id": "F1QNG2_DANRE", "url": "https://www.uniprot.org/uniprot/F1QNG2", "type": "external" } ], "mass": 48871.0, "length": 422, "protein_name": "Interferon regulatory factor 7 isoform 1", "gene_name": "irf7", "organism": "Zebrafish", "refseq_name": "interferon regulatory factor 7 isoform 1", "refseq_ac": [ { "id": "NP_956971", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956971", "type": "external" } ], "gene_names_uniprotkb": "irf7; wu:fl24c03; zgc:66043; zgc:77947", "gene_names_refseq": "irf7; wu:fl24c03; zgc:66043; zgc:77947", "protein_names_uniprotkb": "Interferon regulatory factor 7 isoform 1", "protein_names_refseq": "interferon regulatory factor 7 isoform 1", "tax_id": 7955, "disease": "immunodeficiency 39 (Disease Ontology:DOID:0111969)", "pathway": " (dre:393650); (R-DRE-3134963); (R-DRE-9013973); (R-DRE-933541); (R-DRE-936964); (R-DRE-975110)", "pathway_count": 6, "publication_count": 10, "publication_id_list": "18039395;19896215;20438850;20444275;20637800;37598733;38029910;38550983;38636698;39052000", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01011861.1, BC065902.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On Dec 1, 2025 this sequence version replaced NP_956971.2. Transcript Variant: This variant (1) represents the longer variant and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PFL5", "ec_number_list": [], "go_molecular_function": "GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:1902037 negative regulation of hematopoietic stem cell differentiation;GO:0006357 regulation of transcription by RNA polymerase II;GO:0009615 response to virus;GO:0045893 positive regulation of DNA-templated transcription;GO:0045580 regulation of T cell differentiation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QNG2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QNI1-1", "uniprot_id": [ { "id": "F1QNI1_DANRE", "url": "https://www.uniprot.org/uniprot/F1QNI1", "type": "external" } ], "mass": 23588.0, "length": 213, "protein_name": "Complement component 1, q subcomponent-like 4 like precursor", "gene_name": "cbln5", "organism": "Zebrafish", "refseq_name": "complement component 1, q subcomponent-like 4 like precursor", "refseq_ac": [ { "id": "NP_001120808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001120808", "type": "external" } ], "gene_names_uniprotkb": "cbln5; c1ql4l; si:rp71-1g18.3", "gene_names_refseq": "c1ql4l; si:rp71-1g18.3", "protein_names_uniprotkb": "Complement component 1, q subcomponent-like 4 like precursor", "protein_names_refseq": "C1ql2.2; complement component 1, q subcomponent-like 4 like precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100007371)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "18222405;18514183;23586901", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH513062.1, EH515027.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476754, SAMEA4476769 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On or before Aug 15, 2023 this sequence version replaced XP_017207460.1, XP_021326933.1, NP_001120808.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0R4IM28;A0A8M6YTJ4", "ec_number_list": [], "go_molecular_function": "GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0048514 blood vessel morphogenesis;GO:0045930 negative regulation of mitotic cell cycle;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1QNI1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QNI8-1", "uniprot_id": [ { "id": "F1QNI8_DANRE", "url": "https://www.uniprot.org/uniprot/F1QNI8", "type": "external" } ], "mass": 47446.0, "length": 432, "protein_name": "Zona pellucida sperm-binding protein 4", "gene_name": "si:zfos-1505d6.3", "organism": "Zebrafish", "refseq_name": "zona pellucida sperm-binding protein 4", "refseq_ac": [ { "id": "XP_002665864", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002665864", "type": "external" } ], "gene_names_uniprotkb": "si:zfos-1505d6.3", "gene_names_refseq": "si:zfos-1505d6.3", "protein_names_uniprotkb": "Zona pellucida sperm-binding protein 4; Zona pellucida glycoprotein 4; Zona pellucida protein B", "protein_names_refseq": "zona pellucida sperm-binding protein 4", "tax_id": 7955, "disease": "", "pathway": " (dre:100333772); (R-DRE-2534343)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_002665864.1. COMPLETENESS: full length., [RefSeq]; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RE95", "ec_number_list": [], "go_molecular_function": "GO:0035804 structural constituent of egg coat;GO:0032190 acrosin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0035805 egg coat", "go_biological_process": "GO:0007339 binding of sperm to zona pellucida;GO:0060468 prevention of polyspermy", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QNI8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O42357-1", "uniprot_id": [ { "id": "RX2_DANRE", "url": "https://www.uniprot.org/uniprot/O42357", "type": "external" } ], "mass": 37153.0, "length": 327, "protein_name": "Retinal homeobox protein Rx2", "gene_name": "rx2", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "rx2", "gene_names_refseq": "", "protein_names_uniprotkb": "Retinal homeobox protein Rx2", "protein_names_refseq": "", "tax_id": 7955, "disease": "syndromic microphthalmia 16 (Disease Ontology:DOID:0060842); retinitis pigmentosa 95 (Disease Ontology:DOID:0061112); age related macular degeneration 6 (Disease Ontology:DOID:0110018); cone-rod dystrophy 11 (Disease Ontology:DOID:0111018)", "pathway": " (dre:30473)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10473141;12412019;12947416;15183718;15844196;32984302;33833117;35563172;37175759;37227126;9177348", "class_list": "", "function": "Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0060219 camera-type eye photoreceptor cell differentiation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "O42357-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QNV4-1", "uniprot_id": [ { "id": "NU133_DANRE", "url": "https://www.uniprot.org/uniprot/F1QNV4", "type": "external" } ], "mass": 126581.0, "length": 1136, "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "nup133", "organism": "Zebrafish", "refseq_name": "nuclear pore complex protein Nup133", "refseq_ac": [ { "id": "NP_998696", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998696", "type": "external" } ], "gene_names_uniprotkb": "nup133; zgc:55311", "gene_names_refseq": "nup133; wu:fa04e09; zgc:55311", "protein_names_uniprotkb": "Nuclear pore complex protein Nup133; Nucleoporin 133", "protein_names_refseq": "nuclear pore complex protein Nup133", "tax_id": 7955, "disease": "Galloway-Mowat syndrome 1 (Disease Ontology:DOID:0060364); nephrotic syndrome type 18 (Disease Ontology:DOID:0080393); Galloway-Mowat syndrome (Disease Ontology:DOID:0080694)", "pathway": " (dre:406852); (R-DRE-141430); (R-DRE-141444); (R-DRE-159227); (R-DRE-159231); (R-DRE-159236); (R-DRE-1855170); (R-DRE-1855196); (R-DRE-1855229); (R-DRE-191859); (R-DRE-2467813); (R-DRE-2500257); (R-DRE-3108214); (R-DRE-3232142); (R-DRE-3301854); (R-DRE-3371453); (R-DRE-4551638); (R-DRE-5663220); (R-DRE-9615933)", "pathway_count": 19, "publication_count": 4, "publication_id_list": "23594743;30427554;30894603;40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC052764.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505380 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC052764.1. On Jul 6, 2005 this sequence version replaced XP_702701.1., [RefSeq]; Involved in poly(A)+ RNA transport (By similarity). Involved in nephrogenesis (PubMed:30427554)., [UniProtKB, UniProtKB, PubMed]; Moderate Nucleoporin 133 deficiency leads to glomerular damage in zebrafish. Erratum:[Sci Rep. 2020 Jan 15;10(1):756. doi: 10.1038/s41598-020-57829-7. PMID: 31937913] Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q7SZE9", "ec_number_list": [], "go_molecular_function": "GO:0017056 structural constituent of nuclear pore", "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0000776 kinetochore", "go_biological_process": "GO:0048731 system development;GO:0016973 poly(A)+ mRNA export from nucleus;GO:0048513 animal organ development;GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery;GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F1QNV4-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QNX7-1", "uniprot_id": [ { "id": "REN3B_DANRE", "url": "https://www.uniprot.org/uniprot/F1QNX7", "type": "external" } ], "mass": 55912.0, "length": 467, "protein_name": "Regulator of nonsense transcripts 3B", "gene_name": "upf3b", "organism": "Zebrafish", "refseq_name": "regulator of nonsense transcripts 3B", "refseq_ac": [ { "id": "NP_957248", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957248", "type": "external" } ], "gene_names_uniprotkb": "upf3b; rent3b", "gene_names_refseq": "upf3b; zgc:174674; zgc:66390", "protein_names_uniprotkb": "Regulator of nonsense transcripts 3B; UPF3B regulator of nonsense mediated mRNA decay; Up-frameshift suppressor 3 homolog B", "protein_names_refseq": "UPF3 regulator of nonsense transcripts homolog B; regulator of nonsense transcripts 3B; up-frameshift suppressor 3 homolog B", "tax_id": 7955, "disease": "syndromic X-linked intellectual disability 14 (Disease Ontology:DOID:0060821)", "pathway": " (dre:393929); (R-DRE-159236); (R-DRE-72163); (R-DRE-975957)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "19414594;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC055632.1, FM986820.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505373 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC055632.1., [RefSeq]; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF2 stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA upstream of exon-exon junctions., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A2R8QRF9;Q7SXF0", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0032991 protein-containing complex", "go_biological_process": "GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0045727 positive regulation of translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1QNX7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QPC3-1", "uniprot_id": [ { "id": "SARAF_DANRE", "url": "https://www.uniprot.org/uniprot/F1QPC3", "type": "external" } ], "mass": 36742.0, "length": 345, "protein_name": "Store-operated calcium entry-associated regulatory factor", "gene_name": "saraf", "organism": "Zebrafish", "refseq_name": "store-operated calcium entry-associated regulatory factor precursor", "refseq_ac": [ { "id": "NP_001070057", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070057", "type": "external" } ], "gene_names_uniprotkb": "saraf; tmem66; zgc:153286", "gene_names_refseq": "saraf; tmem66; zgc:153286", "protein_names_uniprotkb": "Store-operated calcium entry-associated regulatory factor; SARAF; SOCE-associated regulatory factor; Transmembrane protein 66", "protein_names_refseq": "SOCE-associated regulatory factor; store-operated calcium entry-associated regulatory factor precursor; transmembrane protein 66", "tax_id": 7955, "disease": "", "pathway": " (dre:767649)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124302.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC124302.1., [RefSeq]; Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (stim1 or stim2)-dependent SOCE activity (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "E9QGQ1;Q08CB8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0140268 endoplasmic reticulum-plasma membrane contact site", "go_biological_process": "GO:0006816 calcium ion transport;GO:2001256 regulation of store-operated calcium entry", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1QPC3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QPX0-1", "uniprot_id": [ { "id": "NDNF_DANRE", "url": "https://www.uniprot.org/uniprot/F1QPX0", "type": "external" } ], "mass": 64817.0, "length": 574, "protein_name": "Protein NDNF", "gene_name": "ndnf", "organism": "Zebrafish", "refseq_name": "protein NDNF precursor", "refseq_ac": [ { "id": "NP_001410712", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410712", "type": "external" } ], "gene_names_uniprotkb": "ndnf; wu:fb16h09", "gene_names_refseq": "ndnf; wu:fb16h09", "protein_names_uniprotkb": "Protein NDNF", "protein_names_refseq": "protein NDNF precursor; protein NDNF", "tax_id": 7955, "disease": "hypogonadotropic hypogonadism (Disease Ontology:DOID:0090070)", "pathway": " (dre:561437)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "23559552;23594743;26469318;27189481;31883645", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01052662.1, GFIL01043490.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from GDQQ01052662.1 and GDQH01003955.1. On Aug 15, 2023 this sequence version replaced XP_689934.5., [RefSeq]; Secretory protein that plays a role in various cellular processes. Acts as a chemorepellent acting on gonadotropin-releasing hormone (GnRH) expressing neurons regulating their migration to the hypothalamus (PubMed:31883645). Also promotes neuron migration, growth and survival as well as neurite outgrowth and is involved in the development of the olfactory system. May also act through the regulation of growth factors activity and downstream signaling (By similarity). Also regulates extracellular matrix assembly and cell adhesiveness (By similarity). Promotes endothelial cell survival, vessel formation and plays an important role in the process of revascularization through NOS3-dependent mechanisms (By similarity)., [UniProtKB, UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0030198 extracellular matrix organization;GO:0044344 cellular response to fibroblast growth factor stimulus;GO:0048702 embryonic neurocranium morphogenesis;GO:0021828 gonadotrophin-releasing hormone neuronal migration to the hypothalamus;GO:0007399 nervous system development", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F1QPX0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QPY7-1", "uniprot_id": [ { "id": "F1QPY7_DANRE", "url": "https://www.uniprot.org/uniprot/F1QPY7", "type": "external" } ], "mass": 8436.0, "length": 76, "protein_name": "Small nuclear ribonucleoprotein G", "gene_name": "snrpg", "organism": "Zebrafish", "refseq_name": "small nuclear ribonucleoprotein G isoform 2", "refseq_ac": [ { "id": "NP_001004660", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004660", "type": "external" } ], "gene_names_uniprotkb": "snrpg; zgc:103688", "gene_names_refseq": "snrpg; zgc:103688", "protein_names_uniprotkb": "Small nuclear ribonucleoprotein G; snRNP-G", "protein_names_refseq": "small nuclear ribonucleoprotein G isoform 2", "tax_id": 7955, "disease": "nasopharynx carcinoma (Disease Ontology:DOID:9261)", "pathway": " (dre:447922); (R-DRE-191859); (R-DRE-72163); (R-DRE-72165); (R-DRE-9770562); (R-DRE-9943411)", "pathway_count": 6, "publication_count": 4, "publication_id_list": "23593122;24419317;26137319;27880902", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH570250.1, EH549128.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH549128.1, EH443016.1 and JBMGRA010000023.1. On or before Dec 17, 2014 this sequence version replaced NP_001161373.1, NP_001004660.1. Transcript Variant: This variant (2) represents the longer transcript and encodes the longer isoform (2)., [RefSeq]; Plays a role in pre-mRNA splicing., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N2G4", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0071013 catalytic step 2 spliceosome;GO:0005686 U2 snRNP;GO:0071011 precatalytic spliceosome;GO:0005687 U4 snRNP", "go_biological_process": "GO:0000387 spliceosomal snRNP assembly;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F1QPY7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QQ04-1", "uniprot_id": [ { "id": "F1QQ04_DANRE", "url": "https://www.uniprot.org/uniprot/F1QQ04", "type": "external" } ], "mass": 45629.0, "length": 405, "protein_name": "Serpin H1", "gene_name": "serpinh1b", "organism": "Zebrafish", "refseq_name": "serpin H1b precursor", "refseq_ac": [ { "id": "NP_001296752", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001296752", "type": "external" } ], "gene_names_uniprotkb": "serpinh1b; cb216; fc56b02; hsp47; hsp; id:ibd5060; wu:fc56b02", "gene_names_refseq": "cb216; fc56b02; hsp47; hsp; id:ibd5060; serpinh1b; wu:fc56b02", "protein_names_uniprotkb": "Serpin H1; Collagen-binding protein", "protein_names_refseq": "heat shock protein 47; serpin H1b precursor", "tax_id": 7955, "disease": "osteogenesis imperfecta type 10 (Disease Ontology:DOID:0110346); preterm premature rupture of the membranes (Disease Ontology:DOID:0111144); liver cirrhosis (Disease Ontology:DOID:5082)", "pathway": " (R-DRE-1650814)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "11731487;15533791;16109975;16980978;17251491;36226668;36326068;36755921;37497728;38131137", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395014.748568.1, SRR26395015.1767720.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505374 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jun 16, 2015 this sequence version replaced XP_005157783.1. Transcript Variant: This variant (2) lacks an exon in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P290;A0AC58HA26;F1R7F7", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen", "go_biological_process": "GO:0030199 collagen fibril organization;GO:0031101 fin regeneration", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QQ04-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QQ79-1", "uniprot_id": [ { "id": "F1QQ79_DANRE", "url": "https://www.uniprot.org/uniprot/F1QQ79", "type": "external" } ], "mass": 106161.0, "length": 978, "protein_name": "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "gene_name": "mthfd1l", "organism": "Zebrafish", "refseq_name": "monofunctional C1-tetrahydrofolate synthase, mitochondrial", "refseq_ac": [ { "id": "NP_001229925", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001229925", "type": "external" } ], "gene_names_uniprotkb": "mthfd1l; fk48e08; si:dkey-25e12.5; si:dkey-25e12.6; wu:fk48e08", "gene_names_refseq": "fk48e08; mthfd1l; si:dkey-25e12.5; si:dkey-25e12.6; wu:fk48e08", "protein_names_uniprotkb": "Monofunctional C1-tetrahydrofolate synthase, mitochondrial; 6.3.4.3; Formyltetrahydrofolate synthetase", "protein_names_refseq": "monofunctional C1-tetrahydrofolate synthase, mitochondrial", "tax_id": 7955, "disease": "neural tube defect (Disease Ontology:DOID:0080074)", "pathway": " (dre:100034522); (R-DRE-196757)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "22480165;27189481;31914627;34268314;34358088;39147780", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588723.2564854.1, SRR32588729.10110725.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On Jul 14, 2011 this sequence version replaced XP_003200753.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism complementing thus the enzymatic activities of MTHFD2., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3W3", "ec_number_list": [ { "id": "6.3.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.3", "type": "external" }, { "id": "1.5.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.5", "type": "external" }, { "id": "3.5.4.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.9", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004329 formate-tetrahydrofolate ligase activity;GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0005829 cytosol", "go_biological_process": "GO:0009257 10-formyltetrahydrofolate biosynthetic process;GO:0015942 formate metabolic process;GO:0035999 tetrahydrofolate interconversion", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F1QQ79-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QQA2-1", "uniprot_id": [ { "id": "F1QQA2_DANRE", "url": "https://www.uniprot.org/uniprot/F1QQA2", "type": "external" } ], "mass": 127791.0, "length": 1130, "protein_name": "DNA-directed RNA polymerase subunit beta", "gene_name": "polr3b", "organism": "Zebrafish", "refseq_name": "DNA-directed RNA polymerase III subunit RPC2", "refseq_ac": [ { "id": "XP_021323450", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323450", "type": "external" } ], "gene_names_uniprotkb": "polr3b", "gene_names_refseq": "polr3b", "protein_names_uniprotkb": "DNA-directed RNA polymerase subunit beta; 2.7.7.6", "protein_names_refseq": "DNA-directed RNA polymerase III subunit RPC2", "tax_id": 7955, "disease": "hypomyelinating leukodystrophy (Disease Ontology:DOID:0060786); hypomyelinating leukodystrophy 8 (Disease Ontology:DOID:0060797); Charcot-Marie-Tooth disease (Disease Ontology:DOID:10595)", "pathway": " (dre:562329); (R-DRE-76061); (R-DRE-76066); (R-DRE-76071)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7T7P2", "ec_number_list": [ { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0046872 metal ion binding;GO:0032549 ribonucleoside binding;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005666 RNA polymerase III complex", "go_biological_process": "GO:0009304 tRNA transcription;GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0048565 digestive tract development;GO:0031017 exocrine pancreas development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QQA2-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QQP6-1", "uniprot_id": [ { "id": "F1QQP6_DANRE", "url": "https://www.uniprot.org/uniprot/F1QQP6", "type": "external" } ], "mass": 74567.0, "length": 683, "protein_name": "Bromodomain-containing protein 3a", "gene_name": "brd3a", "organism": "Zebrafish", "refseq_name": "bromodomain-containing protein 3a", "refseq_ac": [ { "id": "NP_001116861", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116861", "type": "external" } ], "gene_names_uniprotkb": "brd3a; brd3; fc01d09; fc74a08; fi36b10; wu:fa13h06; wu:fc01d09; wu:fc74a08; wu:fi04h10; wu:fi36b10", "gene_names_refseq": "brd3a; brd3; fc01d09; fc74a08; fi36b10; wu:fa13h06; wu:fc01d09; wu:fc74a08; wu:fi04h10; wu:fi36b10", "protein_names_uniprotkb": "Bromodomain-containing protein 3a", "protein_names_refseq": "bromodomain containing 3; bromodomain-containing protein 3a", "tax_id": 7955, "disease": "", "pathway": " (dre:327372)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "15520368;16109975;17055577;20102740;24240475;26505118;28076796;28599080;33914736;34329618", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395028.1150246.1, SRR26395012.599238.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505374 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Apr 17, 2008 this sequence version replaced XP_698948.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NGV5;A0AC58I827", "ec_number_list": [], "go_molecular_function": "GO:0140566 histone reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006355 regulation of DNA-templated transcription;GO:0002574 thrombocyte differentiation;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QQP6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QQZ1-1", "uniprot_id": [ { "id": "F1QQZ1_DANRE", "url": "https://www.uniprot.org/uniprot/F1QQZ1", "type": "external" } ], "mass": 147181.0, "length": 1315, "protein_name": "Splicing factor 3B subunit 1", "gene_name": "sf3b1", "organism": "Zebrafish", "refseq_name": "splicing factor 3B subunit 1 isoform X1", "refseq_ac": [ { "id": "XP_684311", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_684311", "type": "external" } ], "gene_names_uniprotkb": "sf3b1", "gene_names_refseq": "sf3b1", "protein_names_uniprotkb": "Splicing factor 3B subunit 1; Pre-mRNA-splicing factor SF3b 155 kDa subunit; Spliceosome-associated protein 155", "protein_names_refseq": "splicing factor 3B subunit 1 isoform X1", "tax_id": 7955, "disease": "myelodysplastic syndrome (Disease Ontology:DOID:0050908); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (R-DRE-5250924); (R-DRE-72165); (R-DRE-9770562); (R-DRE-9943411)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TAM0", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0016607 nuclear speck;GO:0000785 chromatin;GO:0071013 catalytic step 2 spliceosome;GO:0005686 U2 snRNP;GO:0071004 U2-type prespliceosome", "go_biological_process": "GO:0060218 hematopoietic stem cell differentiation;GO:0014032 neural crest cell development;GO:0042981 regulation of apoptotic process;GO:0060216 definitive hemopoiesis;GO:0000245 spliceosomal complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QQZ1-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QQZ8-1", "uniprot_id": [ { "id": "F1QQZ8_DANRE", "url": "https://www.uniprot.org/uniprot/F1QQZ8", "type": "external" } ], "mass": 50594.0, "length": 456, "protein_name": "Synaptotagmin-11b", "gene_name": "syt11b", "organism": "Zebrafish", "refseq_name": "synaptotagmin-11b", "refseq_ac": [ { "id": "NP_001156003", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001156003", "type": "external" } ], "gene_names_uniprotkb": "syt11b", "gene_names_refseq": "syt11b", "protein_names_uniprotkb": "Synaptotagmin-11b", "protein_names_refseq": "synaptotagmin-11b", "tax_id": 7955, "disease": "type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dre:794707)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "15238157;17672888;20078875;26469318;27189481;28252024;38765140;39147780", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC150364.1, SRR32588724.430580.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA4476739, SAMEA4476754 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Jun 27, 2009 this sequence version replaced XP_001334717.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NUT3", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0005544 calcium-dependent phospholipid binding;GO:0000149 SNARE binding;GO:0061891 calcium ion sensor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0045202 synapse;GO:0030659 cytoplasmic vesicle membrane;GO:0070382 exocytic vesicle", "go_biological_process": "GO:0016192 vesicle-mediated transport;GO:0017158 regulation of calcium ion-dependent exocytosis;GO:0006906 vesicle fusion;GO:1903531 negative regulation of secretion by cell;GO:0099502 calcium-dependent activation of synaptic vesicle fusion", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "F1QQZ8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1L8L1-1", "uniprot_id": [ { "id": "Q1L8L1_DANRE", "url": "https://www.uniprot.org/uniprot/Q1L8L1", "type": "external" } ], "mass": 25762.0, "length": 226, "protein_name": "diphosphoinositol-polyphosphate diphosphatase", "gene_name": "nudt4a", "organism": "Zebrafish", "refseq_name": "nudix (nucleoside diphosphate linked moiety X)-type motif 4a isoform 1", "refseq_ac": [ { "id": "NP_001296990", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001296990", "type": "external" } ], "gene_names_uniprotkb": "nudt4a; nudt4; sb:cb946; zgc:110482", "gene_names_refseq": "nudt4a; nudt4; sb:cb946; zgc:110482", "protein_names_uniprotkb": "diphosphoinositol-polyphosphate diphosphatase; 3.6.1.52", "protein_names_refseq": "nudix (nucleoside diphosphate linked moiety X)-type motif 4a isoform 1; nudix (nucleoside diphosphate linked moiety X)-type motif 4", "tax_id": 7955, "disease": "", "pathway": " (dre:378990); (R-DRE-1855167)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15520368;36403304", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC091886.1, GFIL01028922.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH442667.1, JBMGRA010000018.1 and EH561355.1. On Jun 25, 2015 this sequence version replaced XP_005169980.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1)., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P6U7", "ec_number_list": [ { "id": "3.6.1.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.52", "type": "external" } ], "go_molecular_function": "GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity;GO:0003723 RNA binding;GO:0046872 metal ion binding;GO:0000298 endopolyphosphatase activity;GO:0034431 bis(5'-adenosyl)-hexaphosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005634 nucleus", "go_biological_process": "GO:0071543 diphosphoinositol polyphosphate metabolic process;GO:1901907 diadenosine pentaphosphate catabolic process;GO:1901909 diadenosine hexaphosphate catabolic process;GO:1901911 adenosine 5'-(hexahydrogen pentaphosphate) catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q1L8L1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QR78-1", "uniprot_id": [ { "id": "F1QR78_DANRE", "url": "https://www.uniprot.org/uniprot/F1QR78", "type": "external" } ], "mass": 29851.0, "length": 276, "protein_name": "Proteasome subunit beta", "gene_name": "psmb10", "organism": "Zebrafish", "refseq_name": "proteasome subunit beta type-10", "refseq_ac": [ { "id": "NP_001002543", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002543", "type": "external" } ], "gene_names_uniprotkb": "psmb10; beta2i; zgc:92791", "gene_names_refseq": "beta2i; psmb10; zgc:92791", "protein_names_uniprotkb": "Proteasome subunit beta", "protein_names_refseq": "proteasome subunit beta 10; proteasome subunit beta type-10", "tax_id": 7955, "disease": "Omenn syndrome (Disease Ontology:DOID:0060010); proteosome-associated autoinflammatory syndrome 5 (Disease Ontology:DOID:0060919); immunodeficiency 121 (Disease Ontology:DOID:0061087)", "pathway": " (dre:436816); (R-DRE-1236974); (R-DRE-1236978); (R-DRE-9907900); (R-DRE-9912633)", "pathway_count": 5, "publication_count": 5, "publication_id_list": "26469318;27189481;27493218;28698226;29471808", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC076265.1, GDQH01010525.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On Jun 17, 2016 this sequence version replaced NP_001002543.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity., [UniProtKB, UniProtKB]; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PA63", "ec_number_list": [], "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004298 threonine-type endopeptidase activity", "go_cellular_component": "GO:0019774 proteasome core complex, beta-subunit complex;GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F1QR78-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QRB4-1", "uniprot_id": [ { "id": "F1QRB4_DANRE", "url": "https://www.uniprot.org/uniprot/F1QRB4", "type": "external" } ], "mass": 112197.0, "length": 1030, "protein_name": "Protein transport protein Sec24D", "gene_name": "sec24d", "organism": "Zebrafish", "refseq_name": "protein transport protein Sec24D", "refseq_ac": [ { "id": "NP_001171403", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001171403", "type": "external" } ], "gene_names_uniprotkb": "sec24d", "gene_names_refseq": "sec24d", "protein_names_uniprotkb": "Protein transport protein Sec24D", "protein_names_refseq": "SEC24 family, member D; bulldog; bul; protein transport protein Sec24D", "tax_id": 7955, "disease": "Cole-Carpenter syndrome (Disease Ontology:DOID:0060438)", "pathway": " (dre:553407); (R-DRE-204005); (R-DRE-2132295); (R-DRE-5694530); (R-DRE-983170)", "pathway_count": 5, "publication_count": 6, "publication_id_list": "20442775;21729877;24627348;26469318;27189481;37718532", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GU944484.1, GDQH01005358.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Aug 8, 2023 this sequence version replaced NP_001171403.1., [RefSeq]; Sec24D is indispensable for chondrocyte maturation Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9Q7U8", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000149 SNARE binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane;GO:0070971 endoplasmic reticulum exit site;GO:0030127 COPII vesicle coat", "go_biological_process": "GO:0090110 COPII-coated vesicle cargo loading;GO:0006886 intracellular protein transport;GO:0021549 cerebellum development;GO:0070278 extracellular matrix constituent secretion;GO:0060536 cartilage morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F1QRB4-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QRC1-1", "uniprot_id": [ { "id": "DRC1_DANRE", "url": "https://www.uniprot.org/uniprot/F1QRC1", "type": "external" } ], "mass": 78176.0, "length": 670, "protein_name": "Dynein regulatory complex protein 1", "gene_name": "drc1", "organism": "Zebrafish", "refseq_name": "dynein regulatory complex protein 1", "refseq_ac": [ { "id": "NP_001120940", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001120940", "type": "external" } ], "gene_names_uniprotkb": "drc1; ccdc164; si:dkey-65b13.6", "gene_names_refseq": "ccdc164; drc1; sb:eu1661; si:dkey-65b13.6", "protein_names_uniprotkb": "Dynein regulatory complex protein 1; Coiled-coil domain-containing protein 164", "protein_names_refseq": "coiled-coil domain containing 164; coiled-coil domain-containing protein 164; dynein regulatory complex protein 1", "tax_id": 7955, "disease": "Kartagener syndrome (Disease Ontology:DOID:0050144); visceral heterotaxy (Disease Ontology:DOID:0050545); spermatogenic failure 80 (Disease Ontology:DOID:0070579); primary ciliary dyskinesia 21 (Disease Ontology:DOID:0110596)", "pathway": " (dre:100034551)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC161624.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708836, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC161624.1., [RefSeq]; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B1WB57", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005930 axoneme;GO:0005858 axonemal dynein complex", "go_biological_process": "GO:0060285 cilium-dependent cell motility;GO:0070286 axonemal dynein complex assembly;GO:0003352 regulation of cilium movement", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1QRC1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QRP2-1", "uniprot_id": [ { "id": "F1QRP2_DANRE", "url": "https://www.uniprot.org/uniprot/F1QRP2", "type": "external" } ], "mass": 125081.0, "length": 1135, "protein_name": "Protocadherin-18a isoform X1", "gene_name": "pcdh18a", "organism": "Zebrafish", "refseq_name": "protocadherin-18a isoform X1", "refseq_ac": [ { "id": "XP_005159902", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005159902", "type": "external" } ], "gene_names_uniprotkb": "pcdh18a; id:ibd5114; pcdh18", "gene_names_refseq": "id:ibd5114; pcdh18a; pcdh18", "protein_names_uniprotkb": "Protocadherin-18a isoform X1", "protein_names_refseq": "protocadherin-18a isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B6Q8", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0042074 cell migration involved in gastrulation;GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0055113 epiboly involved in gastrulation with mouth forming second", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QRP2-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QRW4-1", "uniprot_id": [ { "id": "F1QRW4_DANRE", "url": "https://www.uniprot.org/uniprot/F1QRW4", "type": "external" } ], "mass": 31814.0, "length": 272, "protein_name": "Phosphatidylinositol transfer protein beta isoform", "gene_name": "pitpnb", "organism": "Zebrafish", "refseq_name": "phosphatidylinositol transfer protein beta isoform isoform 1", "refseq_ac": [ { "id": "NP_957214", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957214", "type": "external" } ], "gene_names_uniprotkb": "pitpnb; zgc:56092", "gene_names_refseq": "pitpnb; zgc:56092", "protein_names_uniprotkb": "Phosphatidylinositol transfer protein beta isoform", "protein_names_refseq": "phosphatidylinositol transfer protein beta isoform isoform 1; phosphotidylinositol transfer protein, beta", "tax_id": 7955, "disease": "", "pathway": " (dre:393894); (R-DRE-1483196)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "20545905;26004360;26301497;26469318;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC047829.1, CN512283.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000010.1. On Jun 16, 2016 this sequence version replaced NP_957214.1. Transcript Variant: This variant (1) represents the shorter transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Pitpnb expression is particularly robust in double cone cells of the zebrafish retina, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PBY8", "ec_number_list": [], "go_molecular_function": "GO:0031210 phosphatidylcholine binding;GO:0035091 phosphatidylinositol binding;GO:0008526 phosphatidylinositol transfer activity;GO:0008525 phosphatidylcholine transporter activity;GO:0008289 lipid binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005737 cytoplasm;GO:0005789 endoplasmic reticulum membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0035845 photoreceptor cell outer segment organization", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F1QRW4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QSB1-1", "uniprot_id": [ { "id": "F1QSB1_DANRE", "url": "https://www.uniprot.org/uniprot/F1QSB1", "type": "external" } ], "mass": 48464.0, "length": 436, "protein_name": "Caspase-9", "gene_name": "casp9", "organism": "Zebrafish", "refseq_name": "caspase-9", "refseq_ac": [ { "id": "NP_001007405", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007405", "type": "external" } ], "gene_names_uniprotkb": "casp9; im:7136887; zgc:101776", "gene_names_refseq": "casp9; im:7136887; zgc:101776", "protein_names_uniprotkb": "Caspase-9; 3.4.22.62; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6", "protein_names_refseq": "caspase 9, apoptosis-related cysteine protease; caspase-9", "tax_id": 7955, "disease": "stomach cancer (Disease Ontology:DOID:10534); Alzheimer's disease (Disease Ontology:DOID:10652); urinary bladder cancer (Disease Ontology:DOID:11054); Huntington's disease (Disease Ontology:DOID:12858); Parkinson's disease (Disease Ontology:DOID:14330); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); severe acute respiratory syndrome (Disease Ontology:DOID:2945); lung non-small cell carcinoma (Disease Ontology:DOID:3908); diabetic retinopathy (Disease Ontology:DOID:8947); colorectal cancer (Disease Ontology:DOID:9256); type 2 diabetes mellitus (Disease Ontology:DOID:9352); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (dre:492763); (R-DRE-111458); (R-DRE-111459); (R-DRE-198323); (R-DRE-9627069)", "pathway_count": 5, "publication_count": 10, "publication_id_list": "10917738;18510930;19356805;20965546;21316461;38671878;39010883;39145297;39273418;39316747", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01003094.1, GDQH01015333.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH493348.1, EB967264.1, EH440298.1, EH466201.1 and JBMGRA010000023.1. On Apr 11, 2009 this sequence version replaced NP_001007405.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Cleaves BIRC6 following inhibition of BIRC6-caspase binding by DIABLO/SMAC., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 13, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N3B9", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.4.22.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.62", "type": "external" }, { "id": "4.2.1.109", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.109", "type": "external" } ], "go_molecular_function": "GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006508 proteolysis;GO:0043065 positive regulation of apoptotic process;GO:0001822 kidney development;GO:0006915 apoptotic process;GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QSB1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QSI9-1", "uniprot_id": [ { "id": "F1QSI9_DANRE", "url": "https://www.uniprot.org/uniprot/F1QSI9", "type": "external" } ], "mass": 53210.0, "length": 485, "protein_name": "Solute carrier family 3 member 2a", "gene_name": "slc3a2a", "organism": "Zebrafish", "refseq_name": "solute carrier family 3 member 2a", "refseq_ac": [ { "id": "NP_571676", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571676", "type": "external" } ], "gene_names_uniprotkb": "slc3a2a; fc65h12; slc3a2; wu:fc65h12", "gene_names_refseq": "fc65h12; slc3a2a; slc3a2; wu:fc65h12; zion", "protein_names_uniprotkb": "Solute carrier family 3 member 2a", "protein_names_refseq": "solute carrier family 3 (amino acid transporter heavy chain), member 2a; solute carrier family 3 member 2a; solute carrier family 3, member 2", "tax_id": 7955, "disease": "tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); adenoid cystic carcinoma (Disease Ontology:DOID:0080202); lung pleomorphic carcinoma (Disease Ontology:DOID:0080899); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); stomach carcinoma (Disease Ontology:DOID:5517)", "pathway": " (dre:796322); (R-DRE-210991); (R-DRE-352230); (R-DRE-71240)", "pathway_count": 4, "publication_count": 7, "publication_id_list": "11167010;18046332;22331904;25603810;28252024;28694436;30593510", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC159202.1, AF295374.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Jun 25, 2015 this sequence version replaced NP_571676.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Slc3a2 inhibits the RhoA/ROCK pathway via phosphorylation of c-Src to modulate YSL microtubule dynamics. Erratum:[Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5548. Faroq, Sumera [corrected to Farooq, Sumera]], [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PBP2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:1903801 L-leucine import across plasma membrane;GO:0005975 carbohydrate metabolic process;GO:0015823 phenylalanine transport;GO:1904273 L-alanine import across plasma membrane;GO:0060142 regulation of syncytium formation by plasma membrane fusion", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "F1QSI9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08CK1-1", "uniprot_id": [ { "id": "ECSIT_DANRE", "url": "https://www.uniprot.org/uniprot/Q08CK1", "type": "external" } ], "mass": 52186.0, "length": 452, "protein_name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "gene_name": "ecsit", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ecsit; fd13d06; sitpec; wu:fb67e08; wu:fd13d06; zgc:152999", "gene_names_refseq": "", "protein_names_uniprotkb": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:569243); (R-DRE-6799198)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "26469318;28252024;31072958", "class_list": "", "function": "Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B., [UniProtKB]; Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0045087 innate immune response;GO:0032981 mitochondrial respiratory chain complex I assembly;GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathway;GO:0034142 toll-like receptor 4 signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q08CK1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R0E7-1", "uniprot_id": [ { "id": "F1R0E7_DANRE", "url": "https://www.uniprot.org/uniprot/F1R0E7", "type": "external" } ], "mass": 42114.0, "length": 368, "protein_name": "Acyltransferase", "gene_name": "mogat2", "organism": "Zebrafish", "refseq_name": "2-acylglycerol O-acyltransferase 2 isoform 1", "refseq_ac": [ { "id": "NP_001313629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313629", "type": "external" } ], "gene_names_uniprotkb": "mogat2; wu:fb94h05; zgc:101667", "gene_names_refseq": "mogat2; wu:fb94h05; zgc:101667", "protein_names_uniprotkb": "Acyltransferase; 2.3.1.-", "protein_names_refseq": "2-acylglycerol O-acyltransferase 2 isoform 1; MGAT2", "tax_id": 7955, "disease": "", "pathway": " (dre:450063); (R-DRE-75109)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "20374941;23947337;29778665;30336314;31295059;31950220;35427795", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01026626.1, GDQH01000227.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000010.1. On May 24, 2016 this sequence version replaced XP_005172719.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3L0", "ec_number_list": [ { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "2.3.1.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.22", "type": "external" }, { "id": "2.3.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.20", "type": "external" }, { "id": "2.3.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.76", "type": "external" } ], "go_molecular_function": "GO:0003846 2-acylglycerol O-acyltransferase activity;GO:0004144 diacylglycerol O-acyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0001878 response to yeast;GO:0006629 lipid metabolic process;GO:0006651 diacylglycerol biosynthetic process;GO:0019432 triglyceride biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "F1R0E7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QT45-1", "uniprot_id": [ { "id": "F1QT45_DANRE", "url": "https://www.uniprot.org/uniprot/F1QT45", "type": "external" } ], "mass": 75368.0, "length": 667, "protein_name": "Pinin", "gene_name": "pnn", "organism": "Zebrafish", "refseq_name": "pinin", "refseq_ac": [ { "id": "NP_001166041", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001166041", "type": "external" } ], "gene_names_uniprotkb": "pnn; fb24d03; wu:fb24d03", "gene_names_refseq": "fb24d03; pnn; wu:fb24d03", "protein_names_uniprotkb": "Pinin", "protein_names_refseq": "pinin", "tax_id": 7955, "disease": "", "pathway": " (dre:407733); (R-DRE-72163)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "21168434;22527695;24440719;26469318;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC056140.1, BC095809.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EB835206.1, BC081665.1, BM102167.1 and AW203111.1. On Apr 26, 2010 this sequence version replaced XP_001331937.3., [RefSeq]; Pnn is essential for the maintenance of subsets of neural crest cells, and that in zebrafish proper cranial neural crest proliferation and differentiation are dependent on pnn expression., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NUL0", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0016607 nuclear speck;GO:0071013 catalytic step 2 spliceosome;GO:0030057 desmosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0014033 neural crest cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F1QT45-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QTA6-1", "uniprot_id": [ { "id": "F1QTA6_DANRE", "url": "https://www.uniprot.org/uniprot/F1QTA6", "type": "external" } ], "mass": 57091.0, "length": 502, "protein_name": "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase", "gene_name": "mgat1a", "organism": "Zebrafish", "refseq_name": "alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase a isoform X1", "refseq_ac": [ { "id": "XP_005157814", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157814", "type": "external" } ], "gene_names_uniprotkb": "mgat1a; zgc:66030", "gene_names_refseq": "mgat1a; zgc:66030", "protein_names_uniprotkb": "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; 2.4.1.101; GNT-I; GlcNAc-T I; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I", "protein_names_refseq": "alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase a isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B420", "ec_number_list": [ { "id": "2.4.1.101", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.101", "type": "external" } ], "go_molecular_function": "GO:0030145 manganese ion binding;GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QTA6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QTC2-1", "uniprot_id": [ { "id": "F1QTC2_DANRE", "url": "https://www.uniprot.org/uniprot/F1QTC2", "type": "external" } ], "mass": 37132.0, "length": 324, "protein_name": "Protein phosphatase 1 regulatory subunit 3C", "gene_name": "ppp1r3ca", "organism": "Zebrafish", "refseq_name": "protein phosphatase 1, regulatory subunit 3Ca", "refseq_ac": [ { "id": "NP_001002376", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002376", "type": "external" } ], "gene_names_uniprotkb": "ppp1r3ca; cb444; sb:cb444; wu:fb50a11; wu:fc17c07; zgc:92069", "gene_names_refseq": "cb444; ppp1r3ca; sb:cb444; wu:fb50a11; wu:fc17c07; zgc:92069", "protein_names_uniprotkb": "Protein phosphatase 1 regulatory subunit 3C", "protein_names_refseq": "protein phosphatase 1, regulatory (inhibitor) subunit 3Ca; protein phosphatase 1, regulatory subunit 3Ca", "tax_id": 7955, "disease": "alcohol use disorder (Disease Ontology:DOID:1574); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dre:436649)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "18629171;19225104;19482995;20526952;21356182;26469318;27189481;29358039;29551495;30252882", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01034805.1, SRR26395028.141271.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000017.1. On or before Jun 26, 2024 this sequence version replaced XP_005158565.1, NP_001002376.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B4W3", "ec_number_list": [], "go_molecular_function": "GO:0008157 protein phosphatase 1 binding;GO:2001069 glycogen binding", "go_cellular_component": "GO:0000164 protein phosphatase type 1 complex", "go_biological_process": "GO:0005978 glycogen biosynthetic process;GO:0005979 regulation of glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QTC2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QTL1-1", "uniprot_id": [ { "id": "F1QTL1_DANRE", "url": "https://www.uniprot.org/uniprot/F1QTL1", "type": "external" } ], "mass": 13632.0, "length": 127, "protein_name": "Histone H2A", "gene_name": "si:ch1073-159d7.11", "organism": "Zebrafish", "refseq_name": "histone cluster 1 H2A family member 11", "refseq_ac": [ { "id": "NP_001136058", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001136058", "type": "external" } ], "gene_names_uniprotkb": "si:ch1073-159d7.11; h2afx2; h2afx3; h2ax2; h2ax3; hist1h2a11; si:ch73-368j24.15; si:dkey-23a13.20; zgc:195633", "gene_names_refseq": "h2afx3; h2ax3; hist1h2a11; zgc:195633", "protein_names_uniprotkb": "Histone H2A", "protein_names_refseq": "H2A histone family member X 1; H2A histone family member X3; H2A.X variant histone family member 3; histone 2, H2a; histone cluster 1 H2A family member 11", "tax_id": 7955, "disease": "", "pathway": " (dre:100001004); (dre:100004011); (dre:100004510); (dre:100151041); (R-DRE-110330); (R-DRE-110331); (R-DRE-201722); (R-DRE-212300); (R-DRE-2299718); (R-DRE-2559580); (R-DRE-2559582); (R-DRE-3214815); (R-DRE-3214858); (R-DRE-427359); (R-DRE-427413); (R-DRE-5250924); (R-DRE-5625886); (R-DRE-5689603); (R-DRE-5689880); (R-DRE-5689901); (R-DRE-68616); (R-DRE-73728); (R-DRE-73772); (R-DRE-8936459); (R-DRE-9018519); (R-DRE-9764725); (R-DRE-9841922); (R-DRE-9843940); (R-DRE-9843970); (R-DRE-9909649); (R-DRE-9940951); (R-DRE-9943411); (R-DRE-9943962)", "pathway_count": 33, "publication_count": 3, "publication_id_list": "27615797;28252024;31336107", "class_list": "", "function": "##Evidence-Data-START## Transcript is intronless :: SRR32588724.704143.1, SRR26395014.973637.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Sep 14, 2016 this sequence version replaced NP_001136058.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PUF2", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046982 protein heterodimerization activity;GO:0030527 structural constituent of chromatin;GO:0140912 membrane destabilizing activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0000786 nucleosome", "go_biological_process": "GO:0045087 innate immune response;GO:0050830 defense response to Gram-positive bacterium;GO:0031507 heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1QTL1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QU39-1", "uniprot_id": [ { "id": "F1QU39_DANRE", "url": "https://www.uniprot.org/uniprot/F1QU39", "type": "external" } ], "mass": 32262.0, "length": 301, "protein_name": "Protein sprouty homolog 2", "gene_name": "spry2", "organism": "Zebrafish", "refseq_name": "protein sprouty homolog 2 isoform X1", "refseq_ac": [ { "id": "XP_005160342", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005160342", "type": "external" } ], "gene_names_uniprotkb": "spry2; wu:fk66h11; wu:fk93e11; zgc:110440", "gene_names_refseq": "spry2; wu:fk66h11; wu:fk93e11; zgc:110440", "protein_names_uniprotkb": "Protein sprouty homolog 2", "protein_names_refseq": "protein sprouty homolog 2 isoform X1", "tax_id": 7955, "disease": "ciliopathy (Disease Ontology:DOID:0060340); intestinal pseudo-obstruction (Disease Ontology:DOID:0080072); IgA glomerulonephritis (Disease Ontology:DOID:2986); achalasia (Disease Ontology:DOID:9164)", "pathway": " (dre:335098); (R-DRE-1295596); (R-DRE-182971)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B743", "ec_number_list": [], "go_molecular_function": "GO:0004860 protein kinase inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0016020 membrane", "go_biological_process": "GO:0046580 negative regulation of Ras protein signal transduction;GO:0001525 angiogenesis;GO:0070373 negative regulation of ERK1 and ERK2 cascade;GO:0060841 venous blood vessel development;GO:0009953 dorsal/ventral pattern formation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QU39-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QU76-1", "uniprot_id": [ { "id": "F1QU76_DANRE", "url": "https://www.uniprot.org/uniprot/F1QU76", "type": "external" } ], "mass": 58784.0, "length": 512, "protein_name": "Cholesterol 7-alpha-monooxygenase", "gene_name": "cyp7a1", "organism": "Zebrafish", "refseq_name": "cytochrome P450 7A1", "refseq_ac": [ { "id": "NP_957467", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957467", "type": "external" } ], "gene_names_uniprotkb": "cyp7a1; cyp7a1a; zgc:63920", "gene_names_refseq": "cyp7a1a; cyp7a1; zgc:63920", "protein_names_uniprotkb": "Cholesterol 7-alpha-monooxygenase; 1.14.14.23", "protein_names_refseq": "cytochrome P450 7A1; cytochrome P450, family 7, subfamily A, polypeptide 1a", "tax_id": 7955, "disease": "metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); morbid obesity (Disease Ontology:DOID:11981)", "pathway": " (dre:394148); (R-DRE-192105); (R-DRE-193368); (R-DRE-193807); (R-DRE-211976)", "pathway_count": 5, "publication_count": 10, "publication_id_list": "18297735;19451134;24002024;24220226;25030662;37271428;37852100;38449808;38474201;39218217", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01010801.1, GFIL01008011.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505391 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On Apr 18, 2014 this sequence version replaced NP_957467.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7V041", "ec_number_list": [ { "id": "1.14.14.23", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.23", "type": "external" } ], "go_molecular_function": "GO:0008123 cholesterol 7-alpha-monooxygenase activity;GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0008395 steroid hydroxylase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006699 bile acid biosynthetic process;GO:0071333 cellular response to glucose stimulus;GO:0042632 cholesterol homeostasis;GO:0006707 cholesterol catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QU76-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QU82-1", "uniprot_id": [ { "id": "F1QU82_DANRE", "url": "https://www.uniprot.org/uniprot/F1QU82", "type": "external" } ], "mass": 41647.0, "length": 373, "protein_name": "mRNA decay activator protein ZFP36", "gene_name": "zfp36l2", "organism": "Zebrafish", "refseq_name": "mRNA decay activator protein ZFP36L2", "refseq_ac": [ { "id": "NP_996938", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996938", "type": "external" } ], "gene_names_uniprotkb": "zfp36l2; fi22c11; wu:fi22c11; zgc:76924", "gene_names_refseq": "fi22c11; wu:fi22c11; zfp36l2; zgc:76924", "protein_names_uniprotkb": "mRNA decay activator protein ZFP36; Zinc finger protein 36", "protein_names_refseq": "mRNA decay activator protein ZFP36L2; zinc finger protein 36, C3H type-like 2", "tax_id": 7955, "disease": "", "pathway": " (dre:333941)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "25556858;26034287;30309860;31680844;32882641;38321215", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC066478.1, GFIL01044073.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476733, SAMEA4476754 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1. On Jun 25, 2025 this sequence version replaced NP_996938.2., [RefSeq]; Genetic association and functional validation of ZFP36L2 in non-syndromic orofacial cleft subtypes. Erratum:[J Hum Genet. 2024 Apr;69(3-4):169. doi: 10.1038/s10038-024-01239-4. PMID: 38443624], [RefSeq, PubMed]; Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B342", "ec_number_list": [], "go_molecular_function": "GO:0000900 mRNA regulatory element binding translation repressor activity;GO:0008270 zinc ion binding;GO:0035925 mRNA 3'-UTR AU-rich region binding;GO:0160134 protein-RNA sequence-specific adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:1904888 cranial skeletal system development;GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening;GO:0061158 3'-UTR-mediated mRNA destabilization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F1QU82-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QUS3-1", "uniprot_id": [ { "id": "F1QUS3_DANRE", "url": "https://www.uniprot.org/uniprot/F1QUS3", "type": "external" } ], "mass": 46752.0, "length": 427, "protein_name": "Zona pellucida sperm-binding protein 4", "gene_name": "zp2.5", "organism": "Zebrafish", "refseq_name": "zona pellucida glycoprotein 2, tandem duplicate 5 precursor", "refseq_ac": [ { "id": "NP_571405", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571405", "type": "external" } ], "gene_names_uniprotkb": "zp2.5; zgc:152728; zp2", "gene_names_refseq": "zgc:152728; zp2.5; zp2", "protein_names_uniprotkb": "Zona pellucida sperm-binding protein 4; Zona pellucida glycoprotein 4; Zona pellucida protein B", "protein_names_refseq": "zona pellucida glycoprotein 2, tandem duplicate 5 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:30593); (R-DRE-2534343)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "16481590;16805104;18335061;19021768;19299318;19879662;24174574", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395012.962611.1, SRR26395062.495623.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708832, SAMEA898399 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On May 25, 2016 this sequence version replaced NP_571405.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor., [UniProtKB, UniProtKB]; Regulation of zebrafish zona pellucida gene activity in developing oocytes., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P7K6", "ec_number_list": [], "go_molecular_function": "GO:0035804 structural constituent of egg coat;GO:0032190 acrosin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0035805 egg coat", "go_biological_process": "GO:0007339 binding of sperm to zona pellucida;GO:0060468 prevention of polyspermy", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "F1QUS3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QUY7-1", "uniprot_id": [ { "id": "F1QUY7_DANRE", "url": "https://www.uniprot.org/uniprot/F1QUY7", "type": "external" } ], "mass": 76175.0, "length": 679, "protein_name": "Transporter", "gene_name": "slc6a1a", "organism": "Zebrafish", "refseq_name": "sodium- and chloride-dependent GABA transporter 1a", "refseq_ac": [ { "id": "NP_001038752", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038752", "type": "external" } ], "gene_names_uniprotkb": "slc6a1a; fj43h03; wu:fj43h03; zgc:136569", "gene_names_refseq": "fj43h03; slc6a1a; wu:fj43h03; zgc:136569", "protein_names_uniprotkb": "Transporter", "protein_names_refseq": "sodium- and chloride-dependent GABA transporter 1a; solute carrier family 6 (neurotransmitter transporter), member 1a; solute carrier family 6 (neurotransmitter transporter, GABA), member 1a", "tax_id": 7955, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); myoclonic-atonic epilepsy (Disease Ontology:DOID:0060475); temporal lobe epilepsy (Disease Ontology:DOID:3328); schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (dre:692318); (R-DRE-442660); (R-DRE-888593)", "pathway_count": 3, "publication_count": 10, "publication_id_list": "26469318;27189481;27453477;28252024;29454044;32278909;32888589;34083748;36417527;39469188", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01038839.1, BC116591.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505387 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Nov 20, 2012 this sequence version replaced NP_001038752.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NAB5", "ec_number_list": [], "go_molecular_function": "GO:0005332 gamma-aminobutyric acid:sodium:chloride symporter activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0030424 axon", "go_biological_process": "GO:0006865 amino acid transport;GO:0035725 sodium ion transmembrane transport;GO:0006836 neurotransmitter transport", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QUY7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QVT2-1", "uniprot_id": [ { "id": "F1QVT2_DANRE", "url": "https://www.uniprot.org/uniprot/F1QVT2", "type": "external" } ], "mass": 64809.0, "length": 575, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "si:dkey-192d15.2", "organism": "Zebrafish", "refseq_name": "uncharacterized protein", "refseq_ac": [ { "id": "XP_068078607", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068078607", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-192d15.2; LOC141375243", "gene_names_refseq": "LOC141375243", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "uncharacterized protein", "tax_id": 7955, "disease": "", "pathway": " (dre:141375243)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P8C6", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus", "go_biological_process": "GO:0006869 lipid transport;GO:0042157 lipoprotein metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QVT2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QVU3-1", "uniprot_id": [ { "id": "F1QVU3_DANRE", "url": "https://www.uniprot.org/uniprot/F1QVU3", "type": "external" } ], "mass": 93936.0, "length": 834, "protein_name": "Villin-1", "gene_name": "vil1", "organism": "Zebrafish", "refseq_name": "villin-1 isoform X1", "refseq_ac": [ { "id": "XP_005167977", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167977", "type": "external" } ], "gene_names_uniprotkb": "vil1; vil1l; zgc:55779", "gene_names_refseq": "vil1l; vil1; zgc:55779", "protein_names_uniprotkb": "Villin-1", "protein_names_refseq": "villin-1 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BFE1", "ec_number_list": [], "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0015629 actin cytoskeleton;GO:0030027 lamellipodium;GO:0001726 ruffle;GO:0005902 microvillus;GO:0032433 filopodium tip", "go_biological_process": "GO:0051016 barbed-end actin filament capping;GO:0008154 actin polymerization or depolymerization;GO:0051014 actin filament severing;GO:2000392 regulation of lamellipodium morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QVU3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QVW0-1", "uniprot_id": [ { "id": "F1QVW0_DANRE", "url": "https://www.uniprot.org/uniprot/F1QVW0", "type": "external" } ], "mass": 15074.0, "length": 139, "protein_name": "Natriuretic peptides A precursor", "gene_name": "nppa", "organism": "Zebrafish", "refseq_name": "natriuretic peptides A precursor", "refseq_ac": [ { "id": "NP_942095", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_942095", "type": "external" } ], "gene_names_uniprotkb": "nppa; anf; anp; hm:zeh1304; zeh1304", "gene_names_refseq": "anf; anp; hm:zeh1304; nppa; zeh1304", "protein_names_uniprotkb": "Natriuretic peptides A precursor", "protein_names_refseq": "atrial natriuretic factor; natriuretic peptide precursor A; natriuretic peptides A precursor", "tax_id": 7955, "disease": "familial atrial fibrillation (Disease Ontology:DOID:0050650); stroke (Disease Ontology:DOID:0051061); intrinsic cardiomyopathy (Disease Ontology:DOID:0060036); atrial standstill 2 (Disease Ontology:DOID:0080663); renal hypertension (Disease Ontology:DOID:1073); hypertension (Disease Ontology:DOID:10763); heart disease (Disease Ontology:DOID:114); dilated cardiomyopathy (Disease Ontology:DOID:12930); glomerulonephritis (Disease Ontology:DOID:2921); coronary artery disease (Disease Ontology:DOID:3393); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); chronic kidney disease (Disease Ontology:DOID:784); peritonitis (Disease Ontology:DOID:8283); diabetic retinopathy (Disease Ontology:DOID:8947); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:321442); (R-DRE-5578768)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "14573521;16650823;16921028;17311471;17460765;38533084;38850536;39100923;39219269;39347430", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01028495.1, BC124592.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On Sep 16, 2011 this sequence version replaced NP_942095.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 16, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PDR2", "ec_number_list": [], "go_molecular_function": "GO:0005179 hormone activity;GO:0051427 hormone receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm", "go_biological_process": "GO:0036302 atrioventricular canal development;GO:0006182 cGMP biosynthetic process;GO:0007218 neuropeptide signaling pathway;GO:0097746 blood vessel diameter maintenance;GO:0003085 negative regulation of systemic arterial blood pressure", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QVW0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QW13-1", "uniprot_id": [ { "id": "F1QW13_DANRE", "url": "https://www.uniprot.org/uniprot/F1QW13", "type": "external" } ], "mass": 10570.0, "length": 94, "protein_name": "Progonadoliberin", "gene_name": "gnrh3", "organism": "Zebrafish", "refseq_name": "gonadotropin-releasing hormone 3 precursor", "refseq_ac": [ { "id": "NP_878307", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_878307", "type": "external" } ], "gene_names_uniprotkb": "gnrh3; sGnRH", "gene_names_refseq": "gnrh3; sGnRH", "protein_names_uniprotkb": "Progonadoliberin; GnRH-associated peptide; GnRH; Gonadotropin-releasing hormone; LH-RH; Luliberin; Luteinizing hormone-releasing hormone", "protein_names_refseq": "gonadotropin-releasing hormone 3 precursor", "tax_id": 7955, "disease": "prostatic hypertrophy (Disease Ontology:DOID:11132)", "pathway": " (dre:360141); (R-DRE-375281); (R-DRE-416476)", "pathway_count": 3, "publication_count": 10, "publication_id_list": "12204285;12899844;14678830;15570589;15862551;38199972;38288660;38452838;38710511;39499852", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AJ304429.1, AY657019.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505372, SAMEA3505391 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000017.1. On Aug 22, 2009 this sequence version replaced NP_878307.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; In situ hybridization analysis of expression in adult zebrafish brains; levels quantified in the pituitary, [RefSeq, PubMed]; Stimulates the secretion of gonadotropins., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PAR3", "ec_number_list": [], "go_molecular_function": "GO:0005183 gonadotropin hormone-releasing hormone activity;GO:0031530 gonadotropin-releasing hormone receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007420 brain development;GO:0007548 sex differentiation;GO:0043010 camera-type eye development", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QW13-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QW58-1", "uniprot_id": [ { "id": "F1QW58_DANRE", "url": "https://www.uniprot.org/uniprot/F1QW58", "type": "external" } ], "mass": 86848.0, "length": 759, "protein_name": "Kinesin-like protein", "gene_name": "kif3cb", "organism": "Zebrafish", "refseq_name": "kinesin family member 3Cb", "refseq_ac": [ { "id": "NP_001017849", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017849", "type": "external" } ], "gene_names_uniprotkb": "kif3cb; kif3c; zgc:110160", "gene_names_refseq": "kif3cb; kif3c; zgc:110160", "protein_names_uniprotkb": "Kinesin-like protein", "protein_names_refseq": "kinesin family member 3Cb; kinesin family member 3C", "tax_id": 7955, "disease": "", "pathway": " (dre:550547)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "22308397;26253536;26469318;27038111;27189481;27903883;28252024;28855254", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01014005.1, SRR32588732.5690520.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505375, SAMEA3505381 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000017.1. On Jul 15, 2009 this sequence version replaced NP_001017849.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N5C8", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0005871 kinesin complex", "go_biological_process": "GO:0048731 system development;GO:0060271 cilium assembly;GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "F1QW58-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QW93-1", "uniprot_id": [ { "id": "BRDT_DANRE", "url": "https://www.uniprot.org/uniprot/F1QW93", "type": "external" } ], "mass": 103105.0, "length": 918, "protein_name": "Bromodomain testis-specific protein", "gene_name": "brdt", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "brdt; fi25h02; si:dkeyp-85h7.3; wu:fi25h02", "gene_names_refseq": "", "protein_names_uniprotkb": "Bromodomain testis-specific protein", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "Testis-specific chromatin protein that specifically binds histone H4 acetylated at 'Lys-5' and 'Lys-8' (H4K5ac and H4K8ac, respectively) and plays a key role in spermatogenesis. Required in late pachytene spermatocytes: plays a role in meiotic and post-meiotic cells by binding to acetylated histones at the promoter of specific meiotic and post-meiotic genes, facilitating their activation at the appropriate time. In the post-meiotic phase of spermatogenesis, binds to hyperacetylated histones and participates in their general removal from DNA. Also recognizes and binds a subset of butyrylated histones: able to bind histone H4 butyrylated at 'Lys-8' (H4K8ac), while it is not able to bind H4 butyrylated at 'Lys-5' (H4K5ac)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0140566 histone reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0010628 positive regulation of gene expression;GO:0006355 regulation of DNA-templated transcription;GO:0007140 male meiotic nuclear division", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1QW93-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QW96-1", "uniprot_id": [ { "id": "F1QW96_DANRE", "url": "https://www.uniprot.org/uniprot/F1QW96", "type": "external" } ], "mass": 39765.0, "length": 343, "protein_name": "CD209 antigen", "gene_name": "cd209", "organism": "Zebrafish", "refseq_name": "CD209 antigen", "refseq_ac": [ { "id": "NP_001186302", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186302", "type": "external" } ], "gene_names_uniprotkb": "cd209; DC-SIGN; si:ch211-214k5.1; si:ch211-224h1.3", "gene_names_refseq": "DC-SIGN; cd209; si:ch211-214k5.1; si:ch211-224h1.3", "protein_names_uniprotkb": "CD209 antigen", "protein_names_refseq": "CD209 antigen", "tax_id": 7955, "disease": "extrapulmonary tuberculosis (Disease Ontology:DOID:0050598); rheumatic heart disease (Disease Ontology:DOID:0050827); Coronavirus infectious disease (Disease Ontology:DOID:0080599); bronchopulmonary dysplasia (Disease Ontology:DOID:11650); dengue disease (Disease Ontology:DOID:12205); dengue hemorrhagic fever (Disease Ontology:DOID:12206); aspergillosis (Disease Ontology:DOID:13564); asthma (Disease Ontology:DOID:2841); pulmonary tuberculosis (Disease Ontology:DOID:2957); tuberculosis (Disease Ontology:DOID:399); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); acquired immunodeficiency syndrome (Disease Ontology:DOID:635); pulmonary hypertension (Disease Ontology:DOID:6432)", "pathway": " (dre:100334918); (R-DRE-5621575)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "19890038;24286781;25445909;25596146;30863400;38055273;39557479", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: FJ917709.1 [ECO:0000332] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX897671.5. On Jun 10, 2015 this sequence version replaced NP_001186302.1. Sequence Note: This RefSeq record was created from genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Identification and functional characterization of DC-SIGN/CD209 molecule in zebrafish, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 13, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NXD2", "ec_number_list": [], "go_molecular_function": "GO:0030246 carbohydrate binding;GO:0038187 pattern recognition receptor activity", "go_cellular_component": "GO:0009986 cell surface;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0002468 dendritic cell antigen processing and presentation;GO:0006955 immune response;GO:0002250 adaptive immune response;GO:0002286 T cell activation involved in immune response", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "F1QW96-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QWB4-1", "uniprot_id": [ { "id": "F1QWB4_DANRE", "url": "https://www.uniprot.org/uniprot/F1QWB4", "type": "external" } ], "mass": 47596.0, "length": 429, "protein_name": "Heterogeneous nuclear ribonucleoprotein K", "gene_name": "hnrnpk", "organism": "Zebrafish", "refseq_name": "heterogeneous nuclear ribonucleoprotein K", "refseq_ac": [ { "id": "NP_998159", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998159", "type": "external" } ], "gene_names_uniprotkb": "hnrnpk; hnrpk; wu:fb37h02; wu:fi34c04; zgc:66162", "gene_names_refseq": "hnrnpk; hnrpk; wu:fb37h02; wu:fi34c04; zgc:66162", "protein_names_uniprotkb": "Heterogeneous nuclear ribonucleoprotein K", "protein_names_refseq": "heterogeneous nuclear ribonucleoprotein K", "tax_id": 7955, "disease": "prostate cancer (Disease Ontology:DOID:10283); Raynaud disease (Disease Ontology:DOID:10300); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dre:406267)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11748827;26469318;27189481;28582574;32094353;33871629", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1, EB912144.1, BI704444.1 and DR719329.1. On Dec 2, 2010 this sequence version replaced NP_998159.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B580", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003729 mRNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005681 spliceosomal complex;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006397 mRNA processing;GO:0010629 negative regulation of gene expression;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F1QWB4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QWE3-1", "uniprot_id": [ { "id": "F1QWE3_DANRE", "url": "https://www.uniprot.org/uniprot/F1QWE3", "type": "external" } ], "mass": 106154.0, "length": 952, "protein_name": "receptor protein-tyrosine kinase", "gene_name": "mertka", "organism": "Zebrafish", "refseq_name": "tyrosine-protein kinase Mer", "refseq_ac": [ { "id": "XP_002664277", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664277", "type": "external" } ], "gene_names_uniprotkb": "mertka", "gene_names_refseq": "mertka", "protein_names_uniprotkb": "receptor protein-tyrosine kinase; 2.7.10.1", "protein_names_refseq": "tyrosine-protein kinase Mer", "tax_id": 7955, "disease": "retinitis pigmentosa 38 (Disease Ontology:DOID:0110367)", "pathway": " (dre:100322133); (R-DRE-202733)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_002664277.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RDY4", "ec_number_list": [ { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007399 nervous system development;GO:0016477 cell migration;GO:0006909 phagocytosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QWE3-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QWM8-1", "uniprot_id": [ { "id": "F1QWM8_DANRE", "url": "https://www.uniprot.org/uniprot/F1QWM8", "type": "external" } ], "mass": 38448.0, "length": 348, "protein_name": "Neurogenic differentiation factor", "gene_name": "neurod4", "organism": "Zebrafish", "refseq_name": "neurogenic differentiation factor 4", "refseq_ac": [ { "id": "NP_739568", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_739568", "type": "external" } ], "gene_names_uniprotkb": "neurod4; ath3; zath3", "gene_names_refseq": "ath3; neurod4; zath3", "protein_names_uniprotkb": "Neurogenic differentiation factor", "protein_names_refseq": "atonal-like 3; neurogenic differentiation 4; neurogenic differentiation factor 4", "tax_id": 7955, "disease": "", "pathway": " (dre:266958)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12889068;12890499;15056616;15716337;16889661;36058267;37208785;37567873;37642135;37930995", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC071300.1, GFIL01028148.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505391, SAMEA4476751 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On May 16, 2015 this sequence version replaced NP_739568.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PDX7", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070888 E-box binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007399 nervous system development;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0061564 axon development;GO:0043010 camera-type eye development", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QWM8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QWQ9-1", "uniprot_id": [ { "id": "F1QWQ9_DANRE", "url": "https://www.uniprot.org/uniprot/F1QWQ9", "type": "external" } ], "mass": 63781.0, "length": 568, "protein_name": "PR domain zinc finger protein 14 isoform X1", "gene_name": "prdm14", "organism": "Zebrafish", "refseq_name": "PR domain zinc finger protein 14 isoform X1", "refseq_ac": [ { "id": "XP_005162704", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005162704", "type": "external" } ], "gene_names_uniprotkb": "prdm14; fc16b12; prmd14; wu:fc16b12", "gene_names_refseq": "fc16b12; prdm14; prmd14; wu:fc16b12", "protein_names_uniprotkb": "PR domain zinc finger protein 14 isoform X1", "protein_names_refseq": "PR domain zinc finger protein 14 isoform X1", "tax_id": 7955, "disease": "lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": " (dre:563151)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "18231586;18442396;23136389;24240475;30458291;30630825;38423763", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B9J9", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007409 axonogenesis;GO:0019827 stem cell population maintenance;GO:0031452 negative regulation of heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "F1QWQ9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QWR2-1", "uniprot_id": [ { "id": "F1QWR2_DANRE", "url": "https://www.uniprot.org/uniprot/F1QWR2", "type": "external" } ], "mass": 94530.0, "length": 876, "protein_name": "Threonylcarbamoyl-AMP synthase", "gene_name": "si:ch211-153b23.4", "organism": "Zebrafish", "refseq_name": "uncharacterized protein LOC335392", "refseq_ac": [ { "id": "NP_001292402", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292402", "type": "external" } ], "gene_names_uniprotkb": "si:ch211-153b23.4; fj08f03; fj10b02; im:7041150; wu:fj08f03; wu:fj10b02", "gene_names_refseq": "fj08f03; fj10b02; im:7041150; si:ch211-153b23.4; wu:fj08f03; wu:fj10b02", "protein_names_uniprotkb": "Threonylcarbamoyl-AMP synthase; 2.7.7.87", "protein_names_refseq": "uncharacterized protein LOC335392", "tax_id": 7955, "disease": "", "pathway": " (dre:335392)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "26469318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01007795.1, GFIL01043747.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Jun 25, 2025 this sequence version replaced NP_001292402.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P7C3", "ec_number_list": [ { "id": "2.7.7.87", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.87", "type": "external" } ], "go_molecular_function": "GO:0000049 tRNA binding;GO:0003725 double-stranded RNA binding;GO:0016779 nucleotidyltransferase activity;GO:0061710 L-threonylcarbamoyladenylate synthase", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006450 regulation of translational fidelity", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1QWR2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QX08-1", "uniprot_id": [ { "id": "F1QX08_DANRE", "url": "https://www.uniprot.org/uniprot/F1QX08", "type": "external" } ], "mass": 134863.0, "length": 1190, "protein_name": "Jouberin", "gene_name": "ahi1", "organism": "Zebrafish", "refseq_name": "jouberin", "refseq_ac": [ { "id": "NP_001306918", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001306918", "type": "external" } ], "gene_names_uniprotkb": "ahi1", "gene_names_refseq": "ahi1", "protein_names_uniprotkb": "Jouberin", "protein_names_refseq": "ZAhi-1; jouberin", "tax_id": 7955, "disease": "Joubert syndrome (Disease Ontology:DOID:0050777); autism spectrum disorder (Disease Ontology:DOID:0060041); Joubert syndrome 3 (Disease Ontology:DOID:0110998); Joubert syndrome 4 (Disease Ontology:DOID:0110999); nephronophthisis (Disease Ontology:DOID:12712); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:562701)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "16817020;18785627;21959375;25616960;26469318;27189481;28118669;30949029;33914736", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01019081.1, SRR32588730.21229887.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EB855290.1, EH466743.1, JBMGRA010000017.1 and EB931323.1. On Feb 9, 2016 this sequence version replaced XP_009291095.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the reference strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data., [RefSeq]; A role for Ahi1 in epithelial cell organization and ciliary formation and explain the ciliopathy phenotype of AHI1 mutations in man., [RefSeq, PubMed]; Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation. As a positive modulator of classical Wnt signaling, may play a crucial role in ciliary signaling during cerebellum embryonic development., [UniProtKB, UniProtKB]; Results describe spatiotemporal expression patterns of AHI1 and orthologs throughout development, in human, mouse, and zebrafish, and suggest roles for AHI1 in neurodevelopmental processes behind most of the neuroanatomical defects in Joubert syndrome., [RefSeq, PubMed]; The ahi1lri46 mutation in zebrafish resulted in shorter cone outer segments but did not affect visual behavior at 5 days after fertilization (dpf)., [RefSeq, PubMed]; We cloned the full cDNA sequence of Ahi-1 homologous in zebrafish.RT-PCR reveal that ZAhi-1 expressed highest in the mature gonad. In situ hybridization results of zebrafish gonad show that ZAhi-1 only expressed in the early stages' gamete cells.[ZAhi-1], [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P8J8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005912 adherens junction;GO:0005814 centriole;GO:0036064 ciliary basal body", "go_biological_process": "GO:0007368 determination of left/right symmetry;GO:0035845 photoreceptor cell outer segment organization;GO:0044458 motile cilium assembly;GO:0071599 otic vesicle development;GO:0031290 retinal ganglion cell axon guidance", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "F1QX08-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QX34-1", "uniprot_id": [ { "id": "F1QX34_DANRE", "url": "https://www.uniprot.org/uniprot/F1QX34", "type": "external" } ], "mass": 54991.0, "length": 475, "protein_name": "GABA(C) receptor", "gene_name": "gabrr2a", "organism": "Zebrafish", "refseq_name": "gamma-aminobutyric acid receptor subunit rho-2a isoform X1", "refseq_ac": [ { "id": "XP_017207163", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207163", "type": "external" } ], "gene_names_uniprotkb": "gabrr2a; zgc:153417", "gene_names_refseq": "gabrr2a; zgc:153417", "protein_names_uniprotkb": "GABA(C) receptor", "protein_names_refseq": "gamma-aminobutyric acid receptor subunit rho-2a isoform X1", "tax_id": 7955, "disease": "autistic disorder (Disease Ontology:DOID:12849)", "pathway": " (R-DRE-977443)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6YTV3;A0AC58HNL1;A0AC58HNN8;A0AC58HNP4;A0AC58HNR2", "ec_number_list": [ { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" } ], "go_molecular_function": "GO:0005254 chloride channel activity;GO:0004890 GABA-A receptor activity;GO:0005230 extracellular ligand-gated monoatomic ion channel activity", "go_cellular_component": "GO:0045211 postsynaptic membrane;GO:0034707 chloride channel complex;GO:1902711 GABA-A receptor complex", "go_biological_process": "GO:1902476 chloride transmembrane transport;GO:0051932 synaptic transmission, GABAergic", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QX34-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QX91-1", "uniprot_id": [ { "id": "ZD23B_DANRE", "url": "https://www.uniprot.org/uniprot/F1QX91", "type": "external" } ], "mass": 48309.0, "length": 428, "protein_name": "Palmitoyltransferase ZDHHC23-B", "gene_name": "zdhhc23b", "organism": "Zebrafish", "refseq_name": "palmitoyltransferase ZDHHC23-B", "refseq_ac": [ { "id": "NP_001003757", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003757", "type": "external" } ], "gene_names_uniprotkb": "zdhhc23b; zdhhc23; zgc:100848", "gene_names_refseq": "zdhhc23b; zdhhc23; zgc:100848", "protein_names_uniprotkb": "Palmitoyltransferase ZDHHC23-B; 2.3.1.225; Zinc finger DHHC domain-containing protein 23-B", "protein_names_refseq": "palmitoyltransferase ZDHHC23-B; palmitoyltransferase ZDHHC23; zinc finger DHHC domain-containing protein 23-B; zinc finger DHHC-type containing 23b; zinc finger DHHC-type palmitoyltransferase 23b; zinc finger, DHHC-type containing 23", "tax_id": 7955, "disease": "", "pathway": " (dre:445301)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC079487.1, GDQQ01022629.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476787 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079487.1. On Jul 6, 2005 this sequence version replaced XP_701543.1., [RefSeq]; Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates and be involved in a variety of cellular processes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6AXL7", "ec_number_list": [ { "id": "2.3.1.225", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.225", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" } ], "go_molecular_function": "GO:0019706 protein-cysteine S-palmitoyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0072659 protein localization to plasma membrane;GO:0006612 protein targeting to membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1QX91-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QXF4-1", "uniprot_id": [ { "id": "F1QXF4_DANRE", "url": "https://www.uniprot.org/uniprot/F1QXF4", "type": "external" } ], "mass": 178422.0, "length": 1560, "protein_name": "THO complex subunit 2", "gene_name": "thoc2", "organism": "Zebrafish", "refseq_name": "THO complex subunit 2 isoform X1", "refseq_ac": [ { "id": "XP_005157191", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157191", "type": "external" } ], "gene_names_uniprotkb": "thoc2; THO; Tho2; fb73e08; fd21d11; si:bz1o18.2; wu:fb73e08; wu:fd21d11", "gene_names_refseq": "THO; Tho2; fb73e08; fd21d11; si:bz1o18.2; thoc2; wu:fb73e08; wu:fd21d11", "protein_names_uniprotkb": "THO complex subunit 2", "protein_names_refseq": "THO complex subunit 2 isoform X1", "tax_id": 7955, "disease": "X-linked intellectual disability-short stature-overweight syndrome (Disease Ontology:DOID:0112056)", "pathway": " (dre:368417); (R-DRE-159236)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "11748827;15256591;15520368;24002024;26469318;36658633;39021799", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B3X8", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0000445 THO complex part of transcription export complex;GO:0000347 THO complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0006406 mRNA export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "F1QXF4-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QXM5-1", "uniprot_id": [ { "id": "LDHD_DANRE", "url": "https://www.uniprot.org/uniprot/F1QXM5", "type": "external" } ], "mass": 53954.0, "length": 497, "protein_name": "D-lactate dehydrogenase, mitochondrial", "gene_name": "ldhd", "organism": "Zebrafish", "refseq_name": "D-lactate dehydrogenase, mitochondrial", "refseq_ac": [ { "id": "NP_956167", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956167", "type": "external" } ], "gene_names_uniprotkb": "ldhd", "gene_names_refseq": "DLD; ldhd; wu:fi36b04; zgc:55447", "protein_names_uniprotkb": "D-lactate dehydrogenase, mitochondrial; 1.1.98.-; DLD; Lactate dehydrogenase D", "protein_names_refseq": "D-lactate dehydrogenase, mitochondrial; probable D-lactate dehydrogenase, mitochondrial", "tax_id": 7955, "disease": "", "pathway": " (dre:334208); (R-DRE-1268020); (R-DRE-9837999)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "23594743;30931947", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC044171.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC044171.1. On Jul 6, 2005 this sequence version replaced XP_702151.1., [RefSeq]; LDHD loss-of-function in zebrafish results in increased concentrations of D-lactate. Publication Status: Online-Only, [RefSeq, PubMed]; The mitochondrial D-lactate dehydrogenase is a stereoselective dehydrogenase that targets a wide variety of D-2-hydroxyacids, particularly those with small to moderately sized hydrophobic groups attached to the C2 atom. It includes D-lactate which is generated in small amounts either endogenously through the methylglyoxal metabolism pathway or exogenously via intestinal bacterial activity and dietary intake. The dehydrogenase acts specifically on D-lactate, not on its stereoisomer L-lactate, and prevents the toxic accumulation of D-lactate in the organism (PubMed:30931947). By converting branched-chain D-2-hydroxyacids into branched-chain ketoacids, it may indirectly regulate branched-chain amino acid metabolism (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q803V9", "ec_number_list": [ { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "2.1.3.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.3.3", "type": "external" }, { "id": "1.1.98.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.98.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0050660 flavin adenine dinucleotide binding;GO:0071949 FAD binding;GO:0004458 D-lactate dehydrogenase (cytochrome) activity;GO:0008720 D-lactate dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:1903457 lactate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1QXM5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1L8T5-1", "uniprot_id": [ { "id": "CING_DANRE", "url": "https://www.uniprot.org/uniprot/Q1L8T5", "type": "external" } ], "mass": 130821.0, "length": 1161, "protein_name": "Cingulin", "gene_name": "cgnb; cgn", "organism": "Zebrafish", "refseq_name": "cingulin isoform 1", "refseq_ac": [ { "id": "NP_001038227", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038227", "type": "external" } ], "gene_names_uniprotkb": "cgnb; cgn; cb117; cgn; im:7137721; sb:cb117; si:dkey-204a24.2", "gene_names_refseq": "cb117; cgnb; cgn; im:7137721; sb:cb117.; sb:cb117; si:dkey-204a24.2", "protein_names_uniprotkb": "Cingulin", "protein_names_refseq": "cingulin isoform 1", "tax_id": 7955, "disease": "", "pathway": " (dre:100005752); (R-DRE-2173791)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC139880.1, GDQH01013777.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476753, SAMEA4476757 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On or before Jul 31, 2025 this sequence version replaced XP_005159443.1, NP_001038227.1., [RefSeq]; Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Note=Localizes to the apical junction complex composed of tight and adherens junctions., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A5D6T7", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0005923 bicellular tight junction;GO:0016459 myosin complex", "go_biological_process": "GO:0000226 microtubule cytoskeleton organization;GO:0048916 posterior lateral line development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1L8T5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QY75-1", "uniprot_id": [ { "id": "APC15_DANRE", "url": "https://www.uniprot.org/uniprot/F1QY75", "type": "external" } ], "mass": 14376.0, "length": 121, "protein_name": "Anaphase-promoting complex subunit 15", "gene_name": "anapc15", "organism": "Zebrafish", "refseq_name": "anaphase-promoting complex subunit 15", "refseq_ac": [ { "id": "NP_001038915", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038915", "type": "external" } ], "gene_names_uniprotkb": "anapc15; APC15; zgc:153425", "gene_names_refseq": "APC15; anapc15; zgc:153425", "protein_names_uniprotkb": "Anaphase-promoting complex subunit 15; APC15", "protein_names_refseq": "anaphase-promoting complex subunit 15", "tax_id": 7955, "disease": "", "pathway": " (dre:751740); (R-DRE-141430); (R-DRE-174048); (R-DRE-174084); (R-DRE-174154); (R-DRE-174178); (R-DRE-174184); (R-DRE-176407); (R-DRE-176408); (R-DRE-176409); (R-DRE-176412); (R-DRE-179409); (R-DRE-2467813); (R-DRE-2559582); (R-DRE-68867); (R-DRE-69017)", "pathway_count": 16, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395062.1420633.1, SRR32588732.20765938.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On or before Jul 21, 2025 this sequence version replaced XP_068069685.1, NP_001038915.1., [RefSeq]; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0P441", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005680 anaphase-promoting complex", "go_biological_process": "GO:0051301 cell division;GO:0031145 anaphase-promoting complex-dependent catabolic process;GO:0070979 protein K11-linked ubiquitination;GO:0070936 protein K48-linked ubiquitination;GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1QY75-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QYC4-1", "uniprot_id": [ { "id": "NEMP2_DANRE", "url": "https://www.uniprot.org/uniprot/F1QYC4", "type": "external" } ], "mass": 54933.0, "length": 479, "protein_name": "Nuclear envelope integral membrane protein 2", "gene_name": "nemp2", "organism": "Zebrafish", "refseq_name": "nuclear envelope integral membrane protein 2 precursor", "refseq_ac": [ { "id": "NP_001410718", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410718", "type": "external" } ], "gene_names_uniprotkb": "nemp2; si:dkey-42h23.3; tmem194b", "gene_names_refseq": "nemp2; si:dkey-42h23.3; tmem194b", "protein_names_uniprotkb": "Nuclear envelope integral membrane protein 2", "protein_names_refseq": "nuclear envelope integral membrane protein 2 precursor; transmembrane protein 194B", "tax_id": 7955, "disease": "", "pathway": " (dre:564612)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "22412924;23594743;26469318;27189481;32923640", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01041084.1, GDQH01006253.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505382, SAMEA3505392 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH591780.1, JBMGRA010000009.1, GDQH01006253.1, GFIL01041084.1, AL720841.1 and EH609277.1. On Aug 15, 2023 this sequence version replaced XP_693037.2., [RefSeq]; Contributes to nuclear envelope stiffness in germ cells (By similarity). Involved in male and female fertility (PubMed:32923640)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005637 nuclear inner membrane", "go_biological_process": "GO:0001556 oocyte maturation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F1QYC4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QYI0-1", "uniprot_id": [ { "id": "F1QYI0_DANRE", "url": "https://www.uniprot.org/uniprot/F1QYI0", "type": "external" } ], "mass": 62013.0, "length": 555, "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "sppl2", "organism": "Zebrafish", "refseq_name": "signal peptide peptidase-like 2 isoform 2 precursor", "refseq_ac": [ { "id": "NP_001038709", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038709", "type": "external" } ], "gene_names_uniprotkb": "sppl2; SPPL2B; wu:fc16e01; wu:fc85d12; zgc:136525", "gene_names_refseq": "SPPL2B; sppl2; wu:fc16e01; wu:fc85d12; zgc:136525", "protein_names_uniprotkb": "Signal peptide peptidase-like 2B", "protein_names_refseq": "signal peptide peptidase-like 2 isoform 2 precursor; signal peptide peptidase-like protein 2", "tax_id": 7955, "disease": "", "pathway": " (dre:325540); (R-DRE-5357905)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "15998642;17047369;26469318;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC044512.1, SRR26395014.1084402.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On Jun 17, 2015 this sequence version replaced NP_001038709.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; SPPL2b is targeted through the secretory pathway to endosomes/lysosomes, whereas SPP and SPPL3 are restricted to the ER., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NA84", "ec_number_list": [], "go_molecular_function": "GO:0042500 aspartic endopeptidase activity, intramembrane cleaving", "go_cellular_component": "GO:0098554 cytoplasmic side of endoplasmic reticulum membrane;GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0005765 lysosomal membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0050819 negative regulation of coagulation;GO:0033619 membrane protein proteolysis;GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F1QYI0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QYM3-1", "uniprot_id": [ { "id": "F1QYM3_DANRE", "url": "https://www.uniprot.org/uniprot/F1QYM3", "type": "external" } ], "mass": 21620.0, "length": 206, "protein_name": "V-type proton ATPase 21 kDa proteolipid subunit c''", "gene_name": "atp6v0b", "organism": "Zebrafish", "refseq_name": "V-type proton ATPase 21 kDa proteolipid subunit c''", "refseq_ac": [ { "id": "NP_955855", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_955855", "type": "external" } ], "gene_names_uniprotkb": "atp6v0b; wu:fb33a01; zgc:63832", "gene_names_refseq": "atp6v0b; wu:fb33a01; zgc:63832", "protein_names_uniprotkb": "V-type proton ATPase 21 kDa proteolipid subunit c''; Vacuolar proton pump 21 kDa proteolipid subunit c''", "protein_names_refseq": "ATPase, H+ transporting, lysosomal V0 subunit b; V-type proton ATPase 21 kDa proteolipid subunit c''; Vacuolar ATP synthase 21 kDa proteolipid subunit", "tax_id": 7955, "disease": "", "pathway": " (dre:321724); (R-DRE-1222556); (R-DRE-77387); (R-DRE-917977); (R-DRE-9639288); (R-DRE-983712)", "pathway_count": 6, "publication_count": 5, "publication_id_list": "18479681;26469318;27189481;31053140;32033529", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01000742.1, GDQH01009694.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505378, SAMEA3505385 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1, EH446151.1, EH563782.1 and EH469642.1. On May 16, 2015 this sequence version replaced NP_955855.1., [RefSeq]; Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment., [UniProtKB, UniProtKB]; Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P9M1", "ec_number_list": [], "go_molecular_function": "GO:0046961 proton-transporting ATPase activity, rotational mechanism", "go_cellular_component": "GO:0016020 membrane;GO:0030665 clathrin-coated vesicle membrane;GO:0033179 proton-transporting V-type ATPase, V0 domain", "go_biological_process": "GO:0060041 retina development in camera-type eye;GO:0048066 developmental pigmentation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F1QYM3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QYS7-1", "uniprot_id": [ { "id": "F1QYS7_DANRE", "url": "https://www.uniprot.org/uniprot/F1QYS7", "type": "external" } ], "mass": 76689.0, "length": 693, "protein_name": "Acetyl-coenzyme A synthetase", "gene_name": "acss1", "organism": "Zebrafish", "refseq_name": "acetyl-coenzyme A synthetase 2-like, mitochondrial", "refseq_ac": [ { "id": "NP_001074125", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074125", "type": "external" } ], "gene_names_uniprotkb": "acss1; cb395; sb:cb395; wu:fa05a10; wu:fc49f03; wu:fi28d10; zgc:113194; zgc:158738", "gene_names_refseq": "acss1; cb395; sb:cb395; wu:fa05a10; wu:fc49f03; wu:fi28d10; zgc:113194; zgc:158738", "protein_names_uniprotkb": "Acetyl-coenzyme A synthetase; 6.2.1.1", "protein_names_refseq": "ACSS1A; acetyl-coenzyme A synthetase 2-like, mitochondrial", "tax_id": 7955, "disease": "", "pathway": " (dre:541435); (R-DRE-71384)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "22313524;28252024", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC159207.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL929023.3, BX511070.4 and BX000364.6. On or before Nov 14, 2008 this sequence version replaced NP_001013578.1, NP_001074125.2., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1ND09", "ec_number_list": [ { "id": "6.2.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.1", "type": "external" }, { "id": "6.2.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.17", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016208 AMP binding;GO:0003987 acetate-CoA ligase activity;GO:0050218 propionate-CoA ligase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0006085 acetyl-CoA biosynthetic process;GO:0019427 acetyl-CoA biosynthetic process from acetate", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1QYS7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QYZ6-1", "uniprot_id": [ { "id": "F1QYZ6_DANRE", "url": "https://www.uniprot.org/uniprot/F1QYZ6", "type": "external" } ], "mass": 129990.0, "length": 1181, "protein_name": "Pyruvate carboxylase", "gene_name": "pcxb", "organism": "Zebrafish", "refseq_name": "pyruvate carboxylase, mitochondrial", "refseq_ac": [ { "id": "NP_571625", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571625", "type": "external" } ], "gene_names_uniprotkb": "pcxb; PYCb; pc; pyc; wu:fb82g08; wu:fj85g01", "gene_names_refseq": "PYCb; pcxb; pc; pyc; wu:fb82g08; wu:fj85g01", "protein_names_uniprotkb": "Pyruvate carboxylase; 6.4.1.1", "protein_names_refseq": "pyruvate carboxylase, mitochondrial", "tax_id": 7955, "disease": "pyruvate carboxylase deficiency disease (Disease Ontology:DOID:3651)", "pathway": " (dre:58068)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "15984772;16109975;16799861;19500364;21538441;31705559;32784920;39021799;39069827;39139065", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AF295372.1, BC162583.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1, EH595604.1, EH613146.1 and EB794119.1. On Aug 27, 2015 this sequence version replaced NP_571625.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second., [UniProtKB, UniProtKB]; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UZL1", "ec_number_list": [ { "id": "6.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.1", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0009374 biotin binding;GO:0004736 pyruvate carboxylase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0006094 gluconeogenesis;GO:0046686 response to cadmium ion", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QYZ6-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QZ15-1", "uniprot_id": [ { "id": "TPRKB_DANRE", "url": "https://www.uniprot.org/uniprot/F1QZ15", "type": "external" } ], "mass": 19597.0, "length": 175, "protein_name": "EKC/KEOPS complex subunit TPRKB", "gene_name": "tprkb", "organism": "Zebrafish", "refseq_name": "EKC/KEOPS complex subunit TPRKB", "refseq_ac": [ { "id": "NP_001007374", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007374", "type": "external" } ], "gene_names_uniprotkb": "tprkb; zgc:101896", "gene_names_refseq": "tprkb; zgc:101896", "protein_names_uniprotkb": "EKC/KEOPS complex subunit TPRKB; PRPK-binding protein; TP53RK-binding protein", "protein_names_refseq": "EKC/KEOPS complex subunit TPRKB; PRPK-binding protein", "tax_id": 7955, "disease": "Galloway-Mowat syndrome 5 (Disease Ontology:DOID:0080247)", "pathway": " (dre:492501)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;28805828;29346415", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC085466.1, CT708733.2 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505386, SAMEA3505388 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC085466.1., [RefSeq]; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Tprkb acts as an allosteric effector that regulates the t(6)A activity of the complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5U3M9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0000408 EKC/KEOPS complex", "go_biological_process": "GO:0002949 tRNA threonylcarbamoyladenosine modification", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1QZ15-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QZ60-1", "uniprot_id": [ { "id": "F1QZ60_DANRE", "url": "https://www.uniprot.org/uniprot/F1QZ60", "type": "external" } ], "mass": 68656.0, "length": 610, "protein_name": "X-ray repair cross-complementing protein 6 isoform X2; X-ray repair cross-complementing protein 6", "gene_name": "xrcc6", "organism": "Zebrafish", "refseq_name": "X-ray repair cross-complementing protein 6", "refseq_ac": [ { "id": "NP_956198", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956198", "type": "external" } ], "gene_names_uniprotkb": "xrcc6; Ku70; g22p1; wu:fi87b06; zgc:64131", "gene_names_refseq": "Ku70; g22p1; wu:fi87b06; xrcc6; zgc:64131", "protein_names_uniprotkb": "X-ray repair cross-complementing protein 6 isoform X2; X-ray repair cross-complementing protein 6", "protein_names_refseq": "Ku70 autoantigen; X-ray repair complementing defective repair in Chinese hamster cells 6; X-ray repair cross-complementing protein 6; thyroid autoantigen 70kDa (Ku antigen)", "tax_id": 7955, "disease": "squamous cell carcinoma (Disease Ontology:DOID:1749); basal cell carcinoma (Disease Ontology:DOID:2513)", "pathway": " (dre:334488); (R-DRE-5693571); (R-DRE-6798695)", "pathway_count": 3, "publication_count": 10, "publication_id_list": "17630212;18522974;23246864;23887927;27149851;30955321;31708433;33221015;33598573;34502338", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC053270.1, GDQQ01009926.1 [ECO:0000332] RNAseq introns :: partial sample support SAMEA3505370, SAMEA3505372 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1, EH591425.1, EH572648.1 and EH608921.1. On or before May 16, 2015 this sequence version replaced XP_009304867.1, NP_956198.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; These results suggest that Ku70 protein plays a crucial role in protecting the developing nervous system from radiation-induced DNA damage during embryogenesis.(Ku70 antigen, Danio rerio), [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PC38;A0AC58GUX2;A0AC58GUY6", "ec_number_list": [ { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.2.-", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "4.2.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003684 damaged DNA binding;GO:0042162 telomeric DNA binding;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0043564 Ku70:Ku80 complex", "go_biological_process": "GO:0006310 DNA recombination;GO:0000723 telomere maintenance;GO:0006303 double-strand break repair via nonhomologous end joining;GO:0010212 response to ionizing radiation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QZ60-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QZF0-1", "uniprot_id": [ { "id": "F1QZF0_DANRE", "url": "https://www.uniprot.org/uniprot/F1QZF0", "type": "external" } ], "mass": 56089.0, "length": 498, "protein_name": "receptor protein serine/threonine kinase", "gene_name": "acvr1bb", "organism": "Zebrafish", "refseq_name": "activin receptor type-1B isoform X1", "refseq_ac": [ { "id": "XP_687633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687633", "type": "external" } ], "gene_names_uniprotkb": "acvr1bb", "gene_names_refseq": "acvr1bb", "protein_names_uniprotkb": "receptor protein serine/threonine kinase; 2.7.11.30", "protein_names_refseq": "activin receptor type-1B isoform X1", "tax_id": 7955, "disease": "stomach cancer (Disease Ontology:DOID:10534); malignant mesothelioma (Disease Ontology:DOID:1790); pancreatic cancer (Disease Ontology:DOID:1793); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung small cell carcinoma (Disease Ontology:DOID:5409)", "pathway": " (R-DRE-1502540)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XP_687633.4. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7T733", "ec_number_list": [ { "id": "2.7.11.30", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.30", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016361 activin receptor activity, type I;GO:0048185 activin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0048179 activin receptor complex", "go_biological_process": "GO:0007399 nervous system development;GO:0071363 cellular response to growth factor stimulus;GO:0032924 activin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1QZF0-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QZR2-1", "uniprot_id": [ { "id": "F1QZR2_DANRE", "url": "https://www.uniprot.org/uniprot/F1QZR2", "type": "external" } ], "mass": 74860.0, "length": 664, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pak4", "organism": "Zebrafish", "refseq_name": "serine/threonine-protein kinase PAK 4", "refseq_ac": [ { "id": "NP_001002222", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002222", "type": "external" } ], "gene_names_uniprotkb": "pak4; im:5916170; wu:fd12b01; zgc:92014", "gene_names_refseq": "im:5916170; pak4; wu:fd12b01; zgc:92014", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase PAK 4", "tax_id": 7955, "disease": "clear cell renal cell carcinoma (Disease Ontology:DOID:4467)", "pathway": " (dre:431769); (R-DRE-9013148); (R-DRE-9013149); (R-DRE-9013404); (R-DRE-9013406); (R-DRE-9013407); (R-DRE-9013408); (R-DRE-9013420); (R-DRE-9013423); (R-DRE-9013424)", "pathway_count": 10, "publication_count": 8, "publication_id_list": "18307296;21788589;23032194;24945275;26469318;27581768;28252024;33051544", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC074067.1, GDQH01004220.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505375, SAMEA3505380 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jun 13, 2025 this sequence version replaced NP_001002222.2., [RefSeq]; Pak4 is dispensable in zebrafish. Publication Status: Online-Only, [RefSeq, PubMed]; Zebrafish pak4 is required for primitive myeloid cell development. Erratum:[Mech Dev. 2013 Nov-Dec;130(11-12):640], [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N060", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.4", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0002573 myeloid leukocyte differentiation;GO:0035556 intracellular signal transduction;GO:0048598 embryonic morphogenesis;GO:0009267 cellular response to starvation;GO:0043408 regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "F1QZR2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QZV4-1", "uniprot_id": [ { "id": "F1QZV4_DANRE", "url": "https://www.uniprot.org/uniprot/F1QZV4", "type": "external" } ], "mass": 32869.0, "length": 309, "protein_name": "Aquaporin-10b isoform X1", "gene_name": "aqp10b", "organism": "Zebrafish", "refseq_name": "aquaporin-10b isoform X1", "refseq_ac": [ { "id": "XP_005159449", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005159449", "type": "external" } ], "gene_names_uniprotkb": "aqp10b; si:dkey-204a24.5", "gene_names_refseq": "aqp10b; si:dkey-204a24.5", "protein_names_uniprotkb": "Aquaporin-10b isoform X1", "protein_names_refseq": "aquaporin-10b isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:100034395); (R-DRE-432047)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "20149227;21477270;27935978;30951885;32327498", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B699", "ec_number_list": [], "go_molecular_function": "GO:0005372 water transmembrane transporter activity;GO:0015168 glycerol transmembrane transporter activity;GO:0015250 water channel activity;GO:0015254 glycerol channel activity;GO:0015204 urea transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0006833 water transport;GO:0015793 glycerol transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F1QZV4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QZW1-1", "uniprot_id": [ { "id": "F1QZW1_DANRE", "url": "https://www.uniprot.org/uniprot/F1QZW1", "type": "external" } ], "mass": 223232.0, "length": 1938, "protein_name": "Myosin-7", "gene_name": "myh7", "organism": "Zebrafish", "refseq_name": "myosin-7", "refseq_ac": [ { "id": "NP_001106204", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106204", "type": "external" } ], "gene_names_uniprotkb": "myh7; mg:cb02g011; smyhc3; vmhc", "gene_names_refseq": "hm:zeh0269; mg:cb02g011; myh7; smyhc3; vmhc; zeh0269", "protein_names_uniprotkb": "Myosin-7", "protein_names_refseq": "myosin-7; ventricular myosin heavy chain", "tax_id": 7955, "disease": "distal arthrogryposis (Disease Ontology:DOID:0050646); cardiomyopathy (Disease Ontology:DOID:0050700); intrinsic cardiomyopathy (Disease Ontology:DOID:0060036); distal myopathy 1 (Disease Ontology:DOID:0070197); familial hypertrophic cardiomyopathy (Disease Ontology:DOID:0080326); congenital myopathy 6 (Disease Ontology:DOID:0080719); atrial heart septal defect 3 (Disease Ontology:DOID:0110108); hypertrophic cardiomyopathy 1 (Disease Ontology:DOID:0110307); hypertrophic cardiomyopathy 14 (Disease Ontology:DOID:0110320); dilated cardiomyopathy 1EE (Disease Ontology:DOID:0110453); dilated cardiomyopathy 1S (Disease Ontology:DOID:0110454); autosomal recessive hyaline body myopathy (Disease Ontology:DOID:0111268); autosomal dominant hyaline body myopathy (Disease Ontology:DOID:0111269); distal arthrogryposis type 1 (Disease Ontology:DOID:0111596); distal arthrogryposis type 2B3 (Disease Ontology:DOID:0111602); distal arthrogryposis type 2A (Disease Ontology:DOID:0111605); heart disease (Disease Ontology:DOID:114); distal myopathy (Disease Ontology:DOID:11720); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); dilated cardiomyopathy (Disease Ontology:DOID:12930); sick sinus syndrome (Disease Ontology:DOID:13884); hypothyroidism (Disease Ontology:DOID:1459); congenital heart disease (Disease Ontology:DOID:1682); atrial heart septal defect (Disease Ontology:DOID:1882); myotonia congenita (Disease Ontology:DOID:2106); inclusion body myositis (Disease Ontology:DOID:3429); Wolff-Parkinson-White syndrome (Disease Ontology:DOID:384); restrictive cardiomyopathy (Disease Ontology:DOID:397); myopathy (Disease Ontology:DOID:423); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); hypoplastic left heart syndrome (Disease Ontology:DOID:9955)", "pathway": " (dre:30616)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10821756;11116087;11591315;12223419;12912923;38412038;38575811;38900908;39133135;39465301", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01043080.1, SRR32588729.25854812.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000002.1. On Dec 20, 2007 this sequence version replaced XP_684394.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 32, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NF11", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0032982 myosin filament;GO:0030016 myofibril;GO:0016460 myosin II complex", "go_biological_process": "GO:0003231 cardiac ventricle development;GO:0055005 ventricular cardiac myofibril assembly;GO:0030049 muscle filament sliding;GO:0060048 cardiac muscle contraction;GO:0007512 adult heart development", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QZW1-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R003-1", "uniprot_id": [ { "id": "F1R003_DANRE", "url": "https://www.uniprot.org/uniprot/F1R003", "type": "external" } ], "mass": 47096.0, "length": 431, "protein_name": "Zona pellucida sperm-binding protein 4", "gene_name": "zp2.1", "organism": "Zebrafish", "refseq_name": "zona pellucida sperm-binding protein 2.1 precursor", "refseq_ac": [ { "id": "NP_001034972", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034972", "type": "external" } ], "gene_names_uniprotkb": "zp2.1; zgc:114013; zgc:114014", "gene_names_refseq": "zgc:114013; zgc:114014; zp2.1", "protein_names_uniprotkb": "Zona pellucida sperm-binding protein 4; Zona pellucida glycoprotein 4; Zona pellucida protein B", "protein_names_refseq": "zona pellucida sperm-binding protein 2.1 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:664700); (R-DRE-2534343)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "19299318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124100.1, SRR32588735.565516.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708832, SAMEA898399 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On May 26, 2016 this sequence version replaced NP_001034972.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N8C7", "ec_number_list": [], "go_molecular_function": "GO:0035804 structural constituent of egg coat;GO:0032190 acrosin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0035805 egg coat", "go_biological_process": "GO:0007339 binding of sperm to zona pellucida;GO:0060468 prevention of polyspermy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1R003-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R166-1", "uniprot_id": [ { "id": "F1R166_DANRE", "url": "https://www.uniprot.org/uniprot/F1R166", "type": "external" } ], "mass": 46818.0, "length": 411, "protein_name": "RNA helicase", "gene_name": "eif4a2", "organism": "Zebrafish", "refseq_name": "eukaryotic initiation factor 4A-II", "refseq_ac": [ { "id": "NP_998616", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998616", "type": "external" } ], "gene_names_uniprotkb": "eif4a2; wu:fd50g11; zgc:63783", "gene_names_refseq": "eif4a2; wu:fd50g11; zgc:63783", "protein_names_uniprotkb": "RNA helicase; 3.6.4.13", "protein_names_refseq": "eukaryotic initiation factor 4A-II; eukaryotic translation initiation factor 4A", "tax_id": 7955, "disease": "neurodevelopmental disorder with hypotonia and speech delay (Disease Ontology:DOID:0070512)", "pathway": " (dre:406760); (R-DRE-156827); (R-DRE-72649); (R-DRE-72662); (R-DRE-72702)", "pathway_count": 5, "publication_count": 7, "publication_id_list": "20160088;26469318;27189481;28252024;30692167;32502192;33728688", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC055242.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH593311.1, DT072464.1, DT067300.1 and EH471406.1. On or before Apr 5, 2014 this sequence version replaced XP_005163336.1, NP_998616.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PH45", "ec_number_list": [ { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003743 translation initiation factor activity;GO:0003724 RNA helicase activity", "go_cellular_component": "", "go_biological_process": "GO:0002183 cytoplasmic translational initiation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "F1R166-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R184-1", "uniprot_id": [ { "id": "F1R184_DANRE", "url": "https://www.uniprot.org/uniprot/F1R184", "type": "external" } ], "mass": 46159.0, "length": 403, "protein_name": "Thioredoxin domain-containing protein 5", "gene_name": "txndc5", "organism": "Zebrafish", "refseq_name": "thioredoxin domain-containing protein 5 precursor", "refseq_ac": [ { "id": "NP_998181", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998181", "type": "external" } ], "gene_names_uniprotkb": "txndc5; wu:fb20a07; wu:fb55b10; zgc:66265", "gene_names_refseq": "txndc5; wu:fb20a07; wu:fb55b10; zgc:66265", "protein_names_uniprotkb": "Thioredoxin domain-containing protein 5; 5.3.4.1; Endoplasmic reticulum resident protein 46; Thioredoxin-like protein p46", "protein_names_refseq": "thioredoxin domain-containing protein 5 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:406289); (R-DRE-432720); (R-DRE-6798695)", "pathway_count": 3, "publication_count": 7, "publication_id_list": "16109975;23412571;26469318;27189481;28252024;30359749;31726584", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC057499.1, GFIL01042395.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505372, SAMEA3505378 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On or before Jun 14, 2024 this sequence version replaced XP_005162560.1, NP_998181.1., [RefSeq]; Protein disulfide isomerase of the endoplasmic reticulum lumen involved in the formation of disulfide bonds in proteins. Can reduce insulin disulfide bonds., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B9N7", "ec_number_list": [ { "id": "3.4.21.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.4", "type": "external" }, { "id": "2.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.1", "type": "external" }, { "id": "3.1.27.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.27.-", "type": "external" }, { "id": "4.6.1.19", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.19", "type": "external" }, { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "3.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.-", "type": "external" }, { "id": "3.2.1.31", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.31", "type": "external" }, { "id": "5.3.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.4.1", "type": "external" }, { "id": "3.1.6.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.4", "type": "external" }, { "id": "3.5.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.4", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "6.3.4.21", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.21", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "5.3.99.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.3", "type": "external" }, { "id": "1.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.5.5", "type": "external" } ], "go_molecular_function": "GO:0016491 oxidoreductase activity;GO:0003756 protein disulfide isomerase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "F1R184-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0P4F7-1", "uniprot_id": [ { "id": "ACSF2_DANRE", "url": "https://www.uniprot.org/uniprot/Q0P4F7", "type": "external" } ], "mass": 67514.0, "length": 606, "protein_name": "Medium-chain acyl-CoA ligase ACSF2, mitochondrial", "gene_name": "acsf2", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "acsf2; im:7145554; wu:fi49b09; zgc:152887", "gene_names_refseq": "", "protein_names_uniprotkb": "Medium-chain acyl-CoA ligase ACSF2, mitochondrial; 6.2.1.2", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:751707); (R-DRE-77289)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "16466575;17762044;26469318;26876635;27189481", "class_list": "", "function": "Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.2.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.2", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0031956 medium-chain fatty acid-CoA ligase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q0P4F7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R1K5-1", "uniprot_id": [ { "id": "F1R1K5_DANRE", "url": "https://www.uniprot.org/uniprot/F1R1K5", "type": "external" } ], "mass": 110730.0, "length": 978, "protein_name": "DNA (cytosine-5-)-methyltransferase", "gene_name": "dnmt3ab", "organism": "Zebrafish", "refseq_name": "DNA (cytosine-5)-methyltransferase 3A isoform 1", "refseq_ac": [ { "id": "NP_001315096", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315096", "type": "external" } ], "gene_names_uniprotkb": "dnmt3ab; dnmt3a1; dnmt6", "gene_names_refseq": "dnmt3a1; dnmt3ab; dnmt6", "protein_names_uniprotkb": "DNA (cytosine-5-)-methyltransferase; 2.1.1.37", "protein_names_refseq": "DNA (cytosine-5)-methyltransferase 3A isoform 1; DNA (cytosine-5-)-methyltransferase 6", "tax_id": 7955, "disease": "myelodysplastic syndrome (Disease Ontology:DOID:0050908); Tatton-Brown-Rahman syndrome (Disease Ontology:DOID:0112339); stomach cancer (Disease Ontology:DOID:10534); lung cancer (Disease Ontology:DOID:1324); prostatitis (Disease Ontology:DOID:14654); congenital heart disease (Disease Ontology:DOID:1682); endometriosis of uterus (Disease Ontology:DOID:288); endometriosis (Disease Ontology:DOID:289); middle cerebral artery infarction (Disease Ontology:DOID:3525); lung carcinoma (Disease Ontology:DOID:3905); T-cell acute lymphoblastic leukemia (Disease Ontology:DOID:5603); hepatocellular carcinoma (Disease Ontology:DOID:684); chronic myeloid leukemia (Disease Ontology:DOID:8552); autoimmune thrombocytopenic purpura (Disease Ontology:DOID:8924); acute myeloid leukemia (Disease Ontology:DOID:9119); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dre:553189)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "15937923;21258815;22450363;23663776;24123478;37980044;38182651;38289455;39010883;39110393", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01008887.1, SRR32588719.350801.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505372, SAMEA3505374 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000017.1. On Jun 8, 2016 this sequence version replaced XP_005158900.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 16, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P4G9", "ec_number_list": [ { "id": "2.1.1.37", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.37", "type": "external" } ], "go_molecular_function": "GO:0003886 DNA (cytosine-5-)-methyltransferase activity;GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0009266 response to temperature stimulus;GO:0010468 regulation of gene expression;GO:0036269 swimming behavior;GO:0032259 methylation;GO:2000983 regulation of ATP citrate synthase activity", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1R1K5-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R1P4-1", "uniprot_id": [ { "id": "F1R1P4_DANRE", "url": "https://www.uniprot.org/uniprot/F1R1P4", "type": "external" } ], "mass": 53667.0, "length": 466, "protein_name": "Sestrin-3", "gene_name": "sesn3", "organism": "Zebrafish", "refseq_name": "sestrin-3", "refseq_ac": [ { "id": "NP_998684", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998684", "type": "external" } ], "gene_names_uniprotkb": "sesn3; cb261; sb:cb261; wu:fb77c04; wu:fc41d03; wu:fd59d12; zgc:56722", "gene_names_refseq": "cb261; sb:cb261; sesn3; wu:fb77c04; wu:fc41d03; wu:fd59d12; zgc:56722", "protein_names_uniprotkb": "Sestrin-3", "protein_names_refseq": "sestrin-3", "tax_id": 7955, "disease": "", "pathway": " (dre:406840); (R-DRE-5628897)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "16109975;17038485;22411201;24092878;25615886;26469318;29344929;30157643", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC045518.1, DQ858217.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1, AW128658.1, AW059325.1, AW128415.1 and AW019446.1. On Sep 4, 2015 this sequence version replaced NP_998684.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PHA2", "ec_number_list": [], "go_molecular_function": "GO:0016684 oxidoreductase activity, acting on peroxide as acceptor;GO:0070728 L-leucine binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0007626 locomotory behavior;GO:0016239 positive regulation of macroautophagy;GO:1904262 negative regulation of TORC1 signaling;GO:1901031 regulation of response to reactive oxygen species;GO:1990253 cellular response to leucine starvation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "F1R1P4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R1X4-1", "uniprot_id": [ { "id": "F1R1X4_DANRE", "url": "https://www.uniprot.org/uniprot/F1R1X4", "type": "external" } ], "mass": 132188.0, "length": 1186, "protein_name": "Endoplasmic reticulum transmembrane helix translocase", "gene_name": "atp13a1", "organism": "Zebrafish", "refseq_name": "endoplasmic reticulum transmembrane helix translocase", "refseq_ac": [ { "id": "NP_001001403", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001403", "type": "external" } ], "gene_names_uniprotkb": "atp13a1; atp13a; hm:zehn0386; wu:fi75c10; zgc:63781", "gene_names_refseq": "atp13a1; atp13a; hm:zehn0386; wu:fi75c10; zgc:63781", "protein_names_uniprotkb": "Endoplasmic reticulum transmembrane helix translocase; Endoplasmic reticulum P5A-ATPase", "protein_names_refseq": "ATPase type 13A1; ATPase type 13A; endoplasmic reticulum transmembrane helix translocase", "tax_id": 7955, "disease": "", "pathway": " (dre:334466); (R-DRE-936837)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "16109975;23123961;26469318;28252024;31636606", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC055391.1, GDQH01000214.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505375 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000003.1. On Sep 28, 2011 this sequence version replaced NP_001001403.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Endoplasmic reticulum translocase required to remove mitochondrial transmembrane proteins mistargeted to the endoplasmic reticulum. Acts as a dislocase that mediates the ATP-dependent extraction of mislocalized mitochondrial transmembrane proteins from the endoplasmic reticulum membrane. Specifically binds mitochondrial tail-anchored transmembrane proteins: has an atypically large substrate-binding pocket that recognizes and binds moderately hydrophobic transmembranes with short hydrophilic lumenal domains., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1MZL3", "ec_number_list": [ { "id": "7.4.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.4.2.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity;GO:0015662 P-type ion transporter activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0015031 protein transport;GO:0055085 transmembrane transport;GO:0006874 intracellular calcium ion homeostasis;GO:0140569 extraction of mislocalized protein from ER membrane", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F1R1X4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R2C3-1", "uniprot_id": [ { "id": "F1R2C3_DANRE", "url": "https://www.uniprot.org/uniprot/F1R2C3", "type": "external" } ], "mass": 74679.0, "length": 683, "protein_name": "Junctophilin", "gene_name": "jph1a", "organism": "Zebrafish", "refseq_name": "junctophilin-1a", "refseq_ac": [ { "id": "NP_001159728", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001159728", "type": "external" } ], "gene_names_uniprotkb": "jph1a; bZ1M12.3; jph1; si:rp71-1m12.3", "gene_names_refseq": "bZ1M12.3; jph1a; jph1; si:rp71-1m12.3", "protein_names_uniprotkb": "Junctophilin", "protein_names_refseq": "junctophilin 1; junctophilin-1a", "tax_id": 7955, "disease": "Charcot-Marie-Tooth disease axonal type 2K (Disease Ontology:DOID:0110167)", "pathway": " (dre:100147894)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "26469318;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588724.740707.1, SRR32588728.29544664.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505378, SAMEA3505384 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000024.1. On May 21, 2010 this sequence version replaced XP_001923110.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NU33", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:0016529 sarcoplasmic reticulum;GO:0030314 junctional membrane complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1R2C3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R2I5-1", "uniprot_id": [ { "id": "F1R2I5_DANRE", "url": "https://www.uniprot.org/uniprot/F1R2I5", "type": "external" } ], "mass": 55857.0, "length": 491, "protein_name": "Alpha-1D adrenergic receptor", "gene_name": "adra1d", "organism": "Zebrafish", "refseq_name": "alpha-1D adrenergic receptor", "refseq_ac": [ { "id": "XP_697043", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697043", "type": "external" } ], "gene_names_uniprotkb": "adra1d", "gene_names_refseq": "adra1d", "protein_names_uniprotkb": "Alpha-1D adrenergic receptor; Alpha-1D adrenoreceptor", "protein_names_refseq": "alpha-1D adrenergic receptor", "tax_id": 7955, "disease": "", "pathway": " (dre:568614); (R-DRE-390696); (R-DRE-416476); (R-DRE-416482)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_697043.1. COMPLETENESS: full length., [RefSeq]; Alpha-1 adrenergic receptors are G protein-coupled receptors for catecholamines that signal through the G(q) family of G proteins, including G(q) and G(11). Upon activation, they stimulate the phosphatidylinositol-calcium second messenger pathway, leading to calcium release from intracellular stores and activation of protein kinase C. ADRA1D binds the catecholamine ligands norepinephrine and epinephrine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TFC1", "ec_number_list": [], "go_molecular_function": "GO:0004938 alpha2-adrenergic receptor activity;GO:0004937 alpha1-adrenergic receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0007267 cell-cell signaling;GO:0043410 positive regulation of MAPK cascade;GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0045907 positive regulation of vasoconstriction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1R2I5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R2X6-1", "uniprot_id": [ { "id": "PSM4B_DANRE", "url": "https://www.uniprot.org/uniprot/F1R2X6", "type": "external" } ], "mass": 209069.0, "length": 1825, "protein_name": "Proteasome activator complex subunit 4B", "gene_name": "psme4b", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "psme4b", "gene_names_refseq": "", "protein_names_uniprotkb": "Proteasome activator complex subunit 4B; Proteasome activator PA200-B", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. Involved in DNA damage response in somatic cells: binds to acetylated histones and promotes degradation of histones (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016504 peptidase activator activity;GO:0070628 proteasome binding", "go_cellular_component": "GO:1990111 spermatoproteasome complex;GO:0005634 nucleus;GO:0005829 cytosol;GO:0016607 nuclear speck", "go_biological_process": "GO:0006281 DNA repair;GO:0006974 DNA damage response;GO:0010499 proteasomal ubiquitin-independent protein catabolic process;GO:0035092 sperm DNA condensation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1R2X6-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R332-1", "uniprot_id": [ { "id": "GAL2A_DANRE", "url": "https://www.uniprot.org/uniprot/F1R332", "type": "external" } ], "mass": 41329.0, "length": 363, "protein_name": "Galanin receptor 2a", "gene_name": "galr2a", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "galr2a", "gene_names_refseq": "", "protein_names_uniprotkb": "Galanin receptor 2a", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (R-DRE-375276); (R-DRE-418594)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "23594743;24517231;27315774;30903017;31474838", "class_list": "", "function": "Receptor for the hormone galanin (PubMed:24517231). Receptor for the hormones spexin-1 and spexin-2 (PubMed:24517231, PubMed:31474838)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004966 galanin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0090663 galanin-activated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F1R332-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R3E5-1", "uniprot_id": [ { "id": "F1R3E5_DANRE", "url": "https://www.uniprot.org/uniprot/F1R3E5", "type": "external" } ], "mass": 62153.0, "length": 558, "protein_name": "Folliculin", "gene_name": "flcn", "organism": "Zebrafish", "refseq_name": "folliculin isoform X1", "refseq_ac": [ { "id": "XP_005157956", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157956", "type": "external" } ], "gene_names_uniprotkb": "flcn; wu:fe38g11; zgc:136982", "gene_names_refseq": "flcn; wu:fe38g11; zgc:136982", "protein_names_uniprotkb": "Folliculin", "protein_names_refseq": "folliculin isoform X1", "tax_id": 7955, "disease": "nonpapillary renal cell carcinoma (Disease Ontology:DOID:0050387); Birt-Hogg-Dube syndrome (Disease Ontology:DOID:0050676); primary spontaneous pneumothorax (Disease Ontology:DOID:0080218); renal cell carcinoma (Disease Ontology:DOID:4450); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (R-DRE-9639288)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B4W4;A0AC58HHG1", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005819 spindle;GO:0005829 cytosol;GO:0005929 cilium", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1R3E5-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R3H6-1", "uniprot_id": [ { "id": "F1R3H6_DANRE", "url": "https://www.uniprot.org/uniprot/F1R3H6", "type": "external" } ], "mass": 69975.0, "length": 625, "protein_name": "Transporter", "gene_name": "slc6a2", "organism": "Zebrafish", "refseq_name": "sodium-dependent noradrenaline transporter", "refseq_ac": [ { "id": "XP_009301625", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301625", "type": "external" } ], "gene_names_uniprotkb": "slc6a2", "gene_names_refseq": "slc6a2", "protein_names_uniprotkb": "Transporter", "protein_names_refseq": "sodium-dependent noradrenaline transporter", "tax_id": 7955, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); autism spectrum disorder (Disease Ontology:DOID:0060041); classic dopamine transporter deficiency syndrome (Disease Ontology:DOID:0070489); dopamine beta-hydroxylase deficiency (Disease Ontology:DOID:0090145); heart conduction disease (Disease Ontology:DOID:10273); hypertension (Disease Ontology:DOID:10763); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); neurocirculatory asthenia (Disease Ontology:DOID:11569); depressive disorder (Disease Ontology:DOID:1596); amphetamine abuse (Disease Ontology:DOID:670)", "pathway": " (dre:565776); (R-DRE-442660)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AUE2;F8W396", "ec_number_list": [], "go_molecular_function": "GO:0005334 norepinephrine:sodium symporter activity;GO:0046872 metal ion binding;GO:0005330 dopamine:sodium symporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0032809 neuronal cell body membrane;GO:0042734 presynaptic membrane", "go_biological_process": "GO:0006865 amino acid transport;GO:0035725 sodium ion transmembrane transport;GO:0015874 norepinephrine transport;GO:0051583 dopamine uptake involved in synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1R3H6-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R419-1", "uniprot_id": [ { "id": "F1R419_DANRE", "url": "https://www.uniprot.org/uniprot/F1R419", "type": "external" } ], "mass": 117719.0, "length": 1060, "protein_name": "Apoptosis-stimulating of p53 protein 2a isoform X1", "gene_name": "tp53bp2a", "organism": "Zebrafish", "refseq_name": "apoptosis-stimulating of p53 protein 2a", "refseq_ac": [ { "id": "NP_999979", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999979", "type": "external" } ], "gene_names_uniprotkb": "tp53bp2a; tp53bp2; wu:fa09h08; wu:fb04e08; zgc:85720", "gene_names_refseq": "tp53bp2a; tp53bp2; wu:fa09h08; wu:fb04e08; zgc:85720", "protein_names_uniprotkb": "Apoptosis-stimulating of p53 protein 2a isoform X1", "protein_names_refseq": "apoptosis-stimulating of p53 protein 2a; aspp2a; tumor protein p53 binding protein, 2", "tax_id": 7955, "disease": "chromosome 1q41-q42 deletion syndrome (Disease Ontology:DOID:0060412)", "pathway": " (R-DRE-6804759)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "24362258", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC070005.1, GFIL01041708.1 [ECO:0000332] RNAseq introns :: partial sample support SAMEA3505370, SAMEA3505371 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On Jul 30, 2025 this sequence version replaced NP_999979.1., [RefSeq]; These findings uncover a novel role of Aspp2 in regulating vertebrate embryonic growth., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B382", "ec_number_list": [], "go_molecular_function": "GO:0002039 p53 binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0007165 signal transduction;GO:0006915 apoptotic process;GO:0042981 regulation of apoptotic process;GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0043009 chordate embryonic development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1R419-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R4Y7-1", "uniprot_id": [ { "id": "CEP83_DANRE", "url": "https://www.uniprot.org/uniprot/F1R4Y7", "type": "external" } ], "mass": 83912.0, "length": 716, "protein_name": "Centrosomal protein of 83 kDa", "gene_name": "cep83", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "cep83; ccdc41", "gene_names_refseq": "", "protein_names_uniprotkb": "Centrosomal protein of 83 kDa; Cep83; Coiled-coil domain-containing protein 41", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "23530209;23594743", "class_list": "", "function": "Component of the distal appendage region of the centriole involved in the initiation of primary cilium assembly., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "H0WF82", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005813 centrosome;GO:0005814 centriole;GO:0097539 ciliary transition fiber", "go_biological_process": "GO:0060271 cilium assembly;GO:0051660 establishment of centrosome localization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1R4Y7-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R540-1", "uniprot_id": [ { "id": "F1R540_DANRE", "url": "https://www.uniprot.org/uniprot/F1R540", "type": "external" } ], "mass": 84288.0, "length": 767, "protein_name": "Reticulon", "gene_name": "rtn1b", "organism": "Zebrafish", "refseq_name": "reticulon-1b isoform 3", "refseq_ac": [ { "id": "NP_001315200", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315200", "type": "external" } ], "gene_names_uniprotkb": "rtn1b; rtn1l; rtn1; wu:fa21b09; wu:fj35h01", "gene_names_refseq": "rtn1b; rtn1l; rtn1; wu:fa21b09; wu:fj35h01", "protein_names_uniprotkb": "Reticulon", "protein_names_refseq": "reticulon 1, like; reticulon-1b isoform 3", "tax_id": 7955, "disease": "", "pathway": " (R-DRE-193634); (R-DRE-8849932)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "12832288;15858203;16109975;17369834;18442396;26469318;27189481;28252024", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AY555034.1, GFIL01020791.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505372, SAMEA3505377 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On Jun 13, 2016 this sequence version replaced XP_005160546.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3N9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0014069 postsynaptic density;GO:0005789 endoplasmic reticulum membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0007420 brain development;GO:0030182 neuron differentiation;GO:0071787 endoplasmic reticulum tubular network formation;GO:1990809 endoplasmic reticulum tubular network membrane organization", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "F1R540-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R5C0-1", "uniprot_id": [ { "id": "F1R5C0_DANRE", "url": "https://www.uniprot.org/uniprot/F1R5C0", "type": "external" } ], "mass": 48144.0, "length": 430, "protein_name": "Synaptotagmin-2 isoform X1", "gene_name": "syt2a", "organism": "Zebrafish", "refseq_name": "synaptotagmin-2 isoform X1", "refseq_ac": [ { "id": "XP_021325566", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325566", "type": "external" } ], "gene_names_uniprotkb": "syt2a", "gene_names_refseq": "syt2a", "protein_names_uniprotkb": "Synaptotagmin-2 isoform X1", "protein_names_refseq": "synaptotagmin-2 isoform X1", "tax_id": 7955, "disease": "congenital myasthenic syndrome 7 (Disease Ontology:DOID:0110659); congenital myasthenic syndrome (Disease Ontology:DOID:3635); neuromuscular junction disease (Disease Ontology:DOID:439)", "pathway": " (dre:567877); (R-DRE-8856825)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TFA7;A0AC58INT1", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0005544 calcium-dependent phospholipid binding;GO:0000149 SNARE binding;GO:0061891 calcium ion sensor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0030672 synaptic vesicle membrane;GO:0070382 exocytic vesicle;GO:0042584 chromaffin granule membrane", "go_biological_process": "GO:0016192 vesicle-mediated transport;GO:0017158 regulation of calcium ion-dependent exocytosis;GO:2000300 regulation of synaptic vesicle exocytosis;GO:0099502 calcium-dependent activation of synaptic vesicle fusion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1R5C0-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R5N2-1", "uniprot_id": [ { "id": "F1R5N2_DANRE", "url": "https://www.uniprot.org/uniprot/F1R5N2", "type": "external" } ], "mass": 209588.0, "length": 1874, "protein_name": "Transport and Golgi organization protein 1 homolog", "gene_name": "mia3", "organism": "Zebrafish", "refseq_name": "transport and Golgi organization protein 1 homolog isoform X1", "refseq_ac": [ { "id": "XP_005160949", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005160949", "type": "external" } ], "gene_names_uniprotkb": "mia3", "gene_names_refseq": "mia3", "protein_names_uniprotkb": "Transport and Golgi organization protein 1 homolog", "protein_names_refseq": "transport and Golgi organization protein 1 homolog isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:567041); (R-DRE-381426); (R-DRE-8957275)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "40044042", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B832", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0070971 endoplasmic reticulum exit site", "go_biological_process": "GO:0042953 lipoprotein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0048701 embryonic cranial skeleton morphogenesis;GO:0009306 protein secretion;GO:0006887 exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1R5N2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R5W5-1", "uniprot_id": [ { "id": "F1R5W5_DANRE", "url": "https://www.uniprot.org/uniprot/F1R5W5", "type": "external" } ], "mass": 35509.0, "length": 322, "protein_name": "Sidoreflexin", "gene_name": "sfxn1", "organism": "Zebrafish", "refseq_name": "sideroflexin-1 isoform X1", "refseq_ac": [ { "id": "XP_005169684", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169684", "type": "external" } ], "gene_names_uniprotkb": "sfxn1; zgc:100851", "gene_names_refseq": "sfxn1; zgc:100851", "protein_names_uniprotkb": "Sidoreflexin", "protein_names_refseq": "sideroflexin-1 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:445143)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Amino acid transporter importing serine, an essential substrate of the mitochondrial branch of the one-carbon pathway, into mitochondria. Mitochondrial serine is then converted to glycine and formate, which exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors. May also transport other amino acids including alanine and cysteine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BGW1;F1QA91", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015075 monoatomic ion transmembrane transporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006730 one-carbon metabolic process;GO:0042541 hemoglobin biosynthetic process;GO:0140300 serine import into mitochondrion;GO:0043362 nucleate erythrocyte maturation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1R5W5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R676-1", "uniprot_id": [ { "id": "F1R676_DANRE", "url": "https://www.uniprot.org/uniprot/F1R676", "type": "external" } ], "mass": 45163.0, "length": 395, "protein_name": "GDP-fucose protein O-fucosyltransferase 1", "gene_name": "pofut1", "organism": "Zebrafish", "refseq_name": "GDP-fucose protein O-fucosyltransferase 1", "refseq_ac": [ { "id": "NP_991281", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_991281", "type": "external" } ], "gene_names_uniprotkb": "pofut1; fut12; zgc:110472", "gene_names_refseq": "fut12; pofut1; zgc:110472", "protein_names_uniprotkb": "GDP-fucose protein O-fucosyltransferase 1; 2.4.1.221; Peptide-O-fucosyltransferase 1", "protein_names_refseq": "GDP-fucose protein O-fucosyltransferase 1", "tax_id": 7955, "disease": "Dowling-Degos disease (Disease Ontology:DOID:0060256)", "pathway": " (dre:403029)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "19369395;21425872;23684010;26469318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01009345.1, SRR26395050.331980.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505375 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH555457.1, EH495993.1, JBMGRA010000023.1, EH588556.1 and EH601111.1. On or before Feb 24, 2016 this sequence version replaced XP_005174161.1, NP_991281.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7V080", "ec_number_list": [ { "id": "2.4.1.221", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.221", "type": "external" }, { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" } ], "go_molecular_function": "GO:0046922 peptide-O-fucosyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0007219 Notch signaling pathway;GO:0036066 protein O-linked glycosylation via fucose;GO:0006004 fucose metabolic process;GO:0008593 regulation of Notch signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F1R676-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R6B2-1", "uniprot_id": [ { "id": "F1R6B2_DANRE", "url": "https://www.uniprot.org/uniprot/F1R6B2", "type": "external" } ], "mass": 25207.0, "length": 224, "protein_name": "Even-skipped-like1 isoform X1", "gene_name": "eve1", "organism": "Zebrafish", "refseq_name": "even-skipped-like1 isoform X1", "refseq_ac": [ { "id": "XP_005171610", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171610", "type": "external" } ], "gene_names_uniprotkb": "eve1; cb872; evx3", "gene_names_refseq": "cb872; eve1; evx3", "protein_names_uniprotkb": "Even-skipped-like1 isoform X1", "protein_names_refseq": "even-skipped-like1 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BIY4", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0009953 dorsal/ventral pattern formation;GO:0007389 pattern specification process;GO:0036342 post-anal tail morphogenesis;GO:0042661 regulation of mesodermal cell fate specification", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1R6B2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R6I3-1", "uniprot_id": [ { "id": "LRC39_DANRE", "url": "https://www.uniprot.org/uniprot/F1R6I3", "type": "external" } ], "mass": 39911.0, "length": 343, "protein_name": "Leucine-rich repeat-containing protein 39", "gene_name": "lrrc39", "organism": "Zebrafish", "refseq_name": "leucine-rich repeat-containing protein 39", "refseq_ac": [ { "id": "NP_001017760", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017760", "type": "external" } ], "gene_names_uniprotkb": "lrrc39; zgc:112088", "gene_names_refseq": "lrrc39; zgc:112088", "protein_names_uniprotkb": "Leucine-rich repeat-containing protein 39; Myomasp; Myosin-interacting M-band-associated stress-responsive protein", "protein_names_refseq": "leucine-rich repeat-containing protein 39; myomasp; myosin-interacting M-band-associated stress-responsive protein", "tax_id": 7955, "disease": "", "pathway": " (dre:550456)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "20847312;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC093194.1, BC153572.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505372, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC093194.1., [RefSeq]; Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress (By similarity). May regulate expression of other M-band proteins via an SRF-dependent pathway (By similarity). Important for normal contractile function in heart (PubMed:20847312)., [UniProtKB, UniProtKB, PubMed]; Reveal myomasp/LRRC39 as a previously unrecognized component of an M-band-associated signaling pathway that regulates cardiomyocyte gene expression in response to biomechanical stress., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8E5F1;Q567F2;Q66I91", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0031430 M band", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0060047 heart contraction;GO:0055008 cardiac muscle tissue morphogenesis;GO:0045214 sarcomere organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1R6I3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R6Y1-1", "uniprot_id": [ { "id": "F1R6Y1_DANRE", "url": "https://www.uniprot.org/uniprot/F1R6Y1", "type": "external" } ], "mass": 139710.0, "length": 1293, "protein_name": "Cyclin-dependent kinase 12", "gene_name": "cdk12", "organism": "Zebrafish", "refseq_name": "uncharacterized protein cdk12", "refseq_ac": [ { "id": "XP_003200579", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200579", "type": "external" } ], "gene_names_uniprotkb": "cdk12", "gene_names_refseq": "cdk12", "protein_names_uniprotkb": "Cyclin-dependent kinase 12; 2.7.11.22; 2.7.11.23; Cell division protein kinase 12", "protein_names_refseq": "uncharacterized protein cdk12", "tax_id": 7955, "disease": "stomach cancer (Disease Ontology:DOID:10534); gastric adenocarcinoma (Disease Ontology:DOID:3717); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dre:100149834); (R-DRE-6796648)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003200579.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RMR6", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0008024 cyclin/CDK positive transcription elongation factor complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0032968 positive regulation of transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1R6Y1-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R789-1", "uniprot_id": [ { "id": "F1R789_DANRE", "url": "https://www.uniprot.org/uniprot/F1R789", "type": "external" } ], "mass": 19404.0, "length": 171, "protein_name": "Uncharacterized protein cetn4", "gene_name": "cetn4", "organism": "Zebrafish", "refseq_name": "uncharacterized protein cetn4", "refseq_ac": [ { "id": "XP_002667227", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002667227", "type": "external" } ], "gene_names_uniprotkb": "cetn4", "gene_names_refseq": "cetn4", "protein_names_uniprotkb": "Uncharacterized protein cetn4", "protein_names_refseq": "uncharacterized protein cetn4", "tax_id": 7955, "disease": "", "pathway": " (dre:795310); (R-DRE-3108214); (R-DRE-380320); (R-DRE-5696394); (R-DRE-5696395); (R-DRE-9646399)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_002667227.1. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1REK0", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005814 centriole", "go_biological_process": "GO:0060271 cilium assembly;GO:0000226 microtubule cytoskeleton organization;GO:0007099 centriole replication;GO:0022027 interkinetic nuclear migration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1R789-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R799-1", "uniprot_id": [ { "id": "F1R799_DANRE", "url": "https://www.uniprot.org/uniprot/F1R799", "type": "external" } ], "mass": 55124.0, "length": 491, "protein_name": "Occludin", "gene_name": "oclna", "organism": "Zebrafish", "refseq_name": "occludin", "refseq_ac": [ { "id": "NP_997997", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997997", "type": "external" } ], "gene_names_uniprotkb": "oclna; ocln; wu:fd23h10; wu:fi13c01; zgc:113992; zgc:56359", "gene_names_refseq": "oclna; ocln; wu:fd23h10; wu:fi13c01; zgc:113992; zgc:56359", "protein_names_uniprotkb": "Occludin", "protein_names_refseq": "occludin", "tax_id": 7955, "disease": "pseudo-TORCH syndrome 1 (Disease Ontology:DOID:0050656); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); transient cerebral ischemia (Disease Ontology:DOID:224); Crohn's disease (Disease Ontology:DOID:8778); diabetic retinopathy (Disease Ontology:DOID:8947)", "pathway": " (dre:405757); (R-DRE-351906)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "17632505;20553723;21291886;21600298;22422859;34722607;36744960;36819708;39039298;39417326", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01004101.1, BC049304.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000010.1. On or before Mar 24, 2009 this sequence version replaced NP_001025145.1, NP_997997.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PI39", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005923 bicellular tight junction;GO:0016324 apical plasma membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0070830 bicellular tight junction assembly", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1R799-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R7B3-1", "uniprot_id": [ { "id": "F1R7B3_DANRE", "url": "https://www.uniprot.org/uniprot/F1R7B3", "type": "external" } ], "mass": 39819.0, "length": 352, "protein_name": "Cathepsin Lb precursor", "gene_name": "ctslb", "organism": "Zebrafish", "refseq_name": "cathepsin Lb precursor", "refseq_ac": [ { "id": "NP_571273", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571273", "type": "external" } ], "gene_names_uniprotkb": "ctslb; catL; cb15; ctsl1b; ctsl; hgg1; wu:fb30g09", "gene_names_refseq": "catL; cb15; cstlb; ctsl1b; ctslb; ctsl; hgg1; wu:fb30g09", "protein_names_uniprotkb": "Cathepsin Lb precursor", "protein_names_refseq": "cathepsin L, 1 b; cathepsin L, b; cathepsin Lb precursor; hatching gland 1; hatching gland gene 1", "tax_id": 7955, "disease": "", "pathway": " (dre:30443)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "19842174;20188722;20463883;27747391;31477754;8045345;9007230;9091181;9118801;9142985", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC108031.1, SRR32588718.25278790.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505372, SAMEA3505373 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1. On or before Sep 29, 2018 this sequence version replaced XP_005169509.1, NP_571273.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BGR3", "ec_number_list": [], "go_molecular_function": "GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005764 lysosome", "go_biological_process": "GO:0051603 proteolysis involved in protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1R7B3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R7M5-1", "uniprot_id": [ { "id": "F1R7M5_DANRE", "url": "https://www.uniprot.org/uniprot/F1R7M5", "type": "external" } ], "mass": 67463.0, "length": 590, "protein_name": "Polypeptide N-acetylgalactosaminyltransferase", "gene_name": "galnt11", "organism": "Zebrafish", "refseq_name": "polypeptide N-acetylgalactosaminyltransferase 11", "refseq_ac": [ { "id": "NP_001070030", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070030", "type": "external" } ], "gene_names_uniprotkb": "galnt11; sb:cb921; wu:fc01a10; zgc:153274", "gene_names_refseq": "galnt11; sb:cb921; wu:fc01a10; zgc:153274", "protein_names_uniprotkb": "Polypeptide N-acetylgalactosaminyltransferase; 2.4.1.-; Protein-UDP acetylgalactosaminyltransferase", "protein_names_refseq": "polypeptide N-acetylgalactosaminyltransferase 11", "tax_id": 7955, "disease": "", "pathway": " (dre:558716); (R-DRE-913709)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "18231586;25493955;26469318;27189481;29843777;36459505", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0R4IWF4;A0A8M1NAZ9;A0AC58IQQ1", "ec_number_list": [ { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" } ], "go_molecular_function": "GO:0005112 Notch binding;GO:0030246 carbohydrate binding;GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0007219 Notch signaling pathway;GO:0006493 protein O-linked glycosylation;GO:0007368 determination of left/right symmetry;GO:0008593 regulation of Notch signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F1R7M5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R7W6-1", "uniprot_id": [ { "id": "F1R7W6_DANRE", "url": "https://www.uniprot.org/uniprot/F1R7W6", "type": "external" } ], "mass": 47688.0, "length": 454, "protein_name": "3-oxoacyl-[acyl-carrier-protein] synthase", "gene_name": "oxsm", "organism": "Zebrafish", "refseq_name": "3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial", "refseq_ac": [ { "id": "XP_693069", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693069", "type": "external" } ], "gene_names_uniprotkb": "oxsm", "gene_names_refseq": "oxsm", "protein_names_uniprotkb": "3-oxoacyl-[acyl-carrier-protein] synthase", "protein_names_refseq": "3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial", "tax_id": 7955, "disease": "", "pathway": " (dre:564649); (R-DRE-9837999)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_693069.4. COMPLETENESS: full length., [RefSeq]; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TE41;A0AC58HZN9", "ec_number_list": [ { "id": "1.1.1.100", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.100", "type": "external" }, { "id": "1.3.1.39", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.39", "type": "external" }, { "id": "2.3.1.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.38", "type": "external" }, { "id": "2.3.1.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.39", "type": "external" }, { "id": "2.3.1.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.41", "type": "external" }, { "id": "2.3.1.85", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.85", "type": "external" }, { "id": "3.1.2.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.14", "type": "external" }, { "id": "4.2.1.59", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.59", "type": "external" } ], "go_molecular_function": "GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006633 fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1R7W6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R892-1", "uniprot_id": [ { "id": "F1R892_DANRE", "url": "https://www.uniprot.org/uniprot/F1R892", "type": "external" } ], "mass": 22506.0, "length": 200, "protein_name": "Synaptosomal-associated protein", "gene_name": "snap23.2", "organism": "Zebrafish", "refseq_name": "synaptosomal-associated protein 23.2", "refseq_ac": [ { "id": "NP_001032194", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032194", "type": "external" } ], "gene_names_uniprotkb": "snap23.2; zgc:123218", "gene_names_refseq": "snap23.2; zgc:123218", "protein_names_uniprotkb": "Synaptosomal-associated protein", "protein_names_refseq": "synaptosomal-associated protein 23.2", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 7, "publication_id_list": "23922661;24947308;25086293;27189481;28252024;30718891;39139065", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH450384.1, EH451080.1 and EH502395.1. On Aug 16, 2013 this sequence version replaced NP_001032194.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N858;A0AC58HNJ0", "ec_number_list": [], "go_molecular_function": "GO:0019905 syntaxin binding;GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043005 neuron projection;GO:0098793 presynapse;GO:0031201 SNARE complex", "go_biological_process": "GO:0006887 exocytosis;GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane;GO:0016082 synaptic vesicle priming", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "F1R892-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R8L8-1", "uniprot_id": [ { "id": "F1R8L8_DANRE", "url": "https://www.uniprot.org/uniprot/F1R8L8", "type": "external" } ], "mass": 14409.0, "length": 129, "protein_name": "Natriuretic peptides B precursor", "gene_name": "nppb", "organism": "Zebrafish", "refseq_name": "natriuretic peptides B precursor", "refseq_ac": [ { "id": "NP_001314705", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314705", "type": "external" } ], "gene_names_uniprotkb": "nppb; bnp; si:ch211-215j19.10", "gene_names_refseq": "bnp; nppb; si:ch211-215j19.10", "protein_names_uniprotkb": "Natriuretic peptides B precursor", "protein_names_refseq": "B-type natriuretic peptide; brain natriuretic peptide; natriuretic peptides B precursor; zmp:0000000639", "tax_id": 7955, "disease": "COVID-19 (Disease Ontology:DOID:0080600); renal hypertension (Disease Ontology:DOID:1073); hypertension (Disease Ontology:DOID:10763); essential hypertension (Disease Ontology:DOID:10825); sickle cell anemia (Disease Ontology:DOID:10923); adult respiratory distress syndrome (Disease Ontology:DOID:11394); heart disease (Disease Ontology:DOID:114); morbid obesity (Disease Ontology:DOID:11981); dilated cardiomyopathy (Disease Ontology:DOID:12930); Kawasaki disease (Disease Ontology:DOID:13378); atherosclerosis (Disease Ontology:DOID:1936); acute kidney failure (Disease Ontology:DOID:3021); liver cirrhosis (Disease Ontology:DOID:5082); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); migraine (Disease Ontology:DOID:6364); pulmonary hypertension (Disease Ontology:DOID:6432); end stage renal disease (Disease Ontology:DOID:783); chronic kidney disease (Disease Ontology:DOID:784); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); pulmonary embolism (Disease Ontology:DOID:9477); systolic heart failure (Disease Ontology:DOID:9651); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:100334610); (R-DRE-5578768)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "22198505;24353062;24920660;24922095;25531915;39100923;39219269;39332186;39347430;39465301", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: CO916238.1, CN177142.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505375, SAMEA3505385 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On May 25, 2016 this sequence version replaced XP_002663270.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 24, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3Q1", "ec_number_list": [], "go_molecular_function": "GO:0005179 hormone activity;GO:0051427 hormone receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm", "go_biological_process": "GO:0036302 atrioventricular canal development;GO:0006182 cGMP biosynthetic process;GO:0007218 neuropeptide signaling pathway;GO:0097746 blood vessel diameter maintenance;GO:0003085 negative regulation of systemic arterial blood pressure", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1R8L8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R8N4-1", "uniprot_id": [ { "id": "F1R8N4_DANRE", "url": "https://www.uniprot.org/uniprot/F1R8N4", "type": "external" } ], "mass": 71136.0, "length": 618, "protein_name": "Matrix metalloproteinase-16 isoform X1", "gene_name": "mmp16b", "organism": "Zebrafish", "refseq_name": "matrix metalloproteinase-16 isoform X1", "refseq_ac": [ { "id": "XP_009295076", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009295076", "type": "external" } ], "gene_names_uniprotkb": "mmp16b", "gene_names_refseq": "mmp16b", "protein_names_uniprotkb": "Matrix metalloproteinase-16 isoform X1", "protein_names_refseq": "matrix metalloproteinase-16 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (dre:572034); (R-DRE-1592389); (R-DRE-9839383)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3AMT4", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0031012 extracellular matrix;GO:0016020 membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization;GO:0001501 skeletal system development;GO:0030574 collagen catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1R8N4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R926-1", "uniprot_id": [ { "id": "F1R926_DANRE", "url": "https://www.uniprot.org/uniprot/F1R926", "type": "external" } ], "mass": 115622.0, "length": 1013, "protein_name": "E3 ubiquitin protein ligase", "gene_name": "rnf20", "organism": "Zebrafish", "refseq_name": "E3 ubiquitin-protein ligase BRE1A", "refseq_ac": [ { "id": "NP_001243104", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243104", "type": "external" } ], "gene_names_uniprotkb": "rnf20", "gene_names_refseq": "rnf20", "protein_names_uniprotkb": "E3 ubiquitin protein ligase; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase BRE1A", "tax_id": 7955, "disease": "breast cancer (Disease Ontology:DOID:1612); congenital heart disease (Disease Ontology:DOID:1682)", "pathway": " (dre:402838); (R-DRE-9013422)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "24240475;26469318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01005529.1, GDQQ01004480.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505381 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Jun 13, 2025 this sequence version replaced NP_001243104.1., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P2G6", "ec_number_list": [ { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0033503 HULC complex", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1R926-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R983-1", "uniprot_id": [ { "id": "CTIP_DANRE", "url": "https://www.uniprot.org/uniprot/F1R983", "type": "external" } ], "mass": 74390.0, "length": 651, "protein_name": "DNA endonuclease RBBP8", "gene_name": "rbbp8", "organism": "Zebrafish", "refseq_name": "DNA endonuclease RBBP8", "refseq_ac": [ { "id": "NP_001012518", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012518", "type": "external" } ], "gene_names_uniprotkb": "rbbp8; zgc:113143", "gene_names_refseq": "rbbp8; zgc:113143", "protein_names_uniprotkb": "DNA endonuclease RBBP8; 3.1.-.-", "protein_names_refseq": "DNA endonuclease RBBP8", "tax_id": 7955, "disease": "Seckel syndrome 2 (Disease Ontology:DOID:0070013)", "pathway": " (dre:503536); (R-DRE-5685938); (R-DRE-5685939); (R-DRE-5685942); (R-DRE-5693537); (R-DRE-5693568); (R-DRE-5693579); (R-DRE-5693607); (R-DRE-5693616); (R-DRE-6804756); (R-DRE-69473)", "pathway_count": 11, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC090186.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476730, SAMEA4476731 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC090186.1., [RefSeq]; Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in DNA-end resection, the first step of double-strand break (DSB) repair through the homologous recombination (HR) pathway. Functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phase facilitating the generation of ssDNA. Specifically promotes the endonuclease activity of the MRN complex to clear DNA ends containing protein adducts: recruited to DSBs by nbn following phosphorylation, and promotes the endonuclease of mre11 to clear protein-DNA adducts and generate clean double-strand break ends., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5EAZ7", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.4.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.-", "type": "external" }, { "id": "2.4.2.30", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.30", "type": "external" }, { "id": "3.1.22.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.22.-", "type": "external" }, { "id": "5.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.1", "type": "external" } ], "go_molecular_function": "GO:0016787 hydrolase activity;GO:0003684 damaged DNA binding;GO:0004519 endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0051301 cell division;GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing;GO:0051321 meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1R983-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R9E8-1", "uniprot_id": [ { "id": "F1R9E8_DANRE", "url": "https://www.uniprot.org/uniprot/F1R9E8", "type": "external" } ], "mass": 65458.0, "length": 583, "protein_name": "Glutamate decarboxylase 2", "gene_name": "gad2", "organism": "Zebrafish", "refseq_name": "glutamate decarboxylase 2", "refseq_ac": [ { "id": "NP_001017708", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017708", "type": "external" } ], "gene_names_uniprotkb": "gad2; GAD65; zgc:112198", "gene_names_refseq": "GAD65; gad2; zgc:112198", "protein_names_uniprotkb": "Glutamate decarboxylase 2; 4.1.1.15; 65 kDa glutamic acid decarboxylase; Glutamate decarboxylase 65 kDa isoform", "protein_names_refseq": "glutamate decarboxylase 2", "tax_id": 7955, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); gestational diabetes (Disease Ontology:DOID:11714); drug psychosis (Disease Ontology:DOID:1742); epilepsy (Disease Ontology:DOID:1826); schizophrenia (Disease Ontology:DOID:5419); amphetamine abuse (Disease Ontology:DOID:670); type 1 diabetes mellitus (Disease Ontology:DOID:9744); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (dre:550403); (R-DRE-888568)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "10331265;10527880;15215305;15515020;36613611;37553760;37663268;39273418;39469188;9634146", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01011127.1, SRR32588729.16452978.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505378, SAMEA3505387 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000024.1. On Mar 21, 2009 this sequence version replaced NP_001017708.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Catalyzes the production of GABA., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N545", "ec_number_list": [ { "id": "4.1.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.15", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004351 glutamate decarboxylase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0031410 cytoplasmic vesicle;GO:0042734 presynaptic membrane", "go_biological_process": "GO:0006540 gamma-aminobutyrate shunt;GO:0009449 gamma-aminobutyric acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1R9E8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R9S3-1", "uniprot_id": [ { "id": "F1R9S3_DANRE", "url": "https://www.uniprot.org/uniprot/F1R9S3", "type": "external" } ], "mass": 73070.0, "length": 661, "protein_name": "Transcription factor IIIB 90 kDa subunit", "gene_name": "brf1a", "organism": "Zebrafish", "refseq_name": "BRF1 general transcription factor IIIB subunit a isoform X1", "refseq_ac": [ { "id": "XP_017214188", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214188", "type": "external" } ], "gene_names_uniprotkb": "brf1a; brf1; wu:fi47f03; zgc:55543", "gene_names_refseq": "brf1a; brf1; wu:fi47f03; zgc:55543", "protein_names_uniprotkb": "Transcription factor IIIB 90 kDa subunit; B-related factor 1", "protein_names_refseq": "BRF1 general transcription factor IIIB subunit a isoform X1", "tax_id": 7955, "disease": "fibroma (Disease Ontology:DOID:0050871); cerebellofaciodental syndrome (Disease Ontology:DOID:0080898); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dre:334402); (R-DRE-76061); (R-DRE-76066)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M6Z1L3", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003743 translation initiation factor activity;GO:0017025 TBP-class protein binding;GO:0001006 RNA polymerase III type 3 promoter sequence-specific DNA binding;GO:0000995 RNA polymerase III general transcription initiation factor activity", "go_cellular_component": "GO:0097550 transcription preinitiation complex;GO:0005634 nucleus;GO:0000126 transcription factor TFIIIB complex", "go_biological_process": "GO:0030223 neutrophil differentiation;GO:0006383 transcription by RNA polymerase III;GO:0006352 DNA-templated transcription initiation;GO:0070897 transcription preinitiation complex assembly;GO:0030099 myeloid cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1R9S3-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1R9X0-1", "uniprot_id": [ { "id": "F1R9X0_DANRE", "url": "https://www.uniprot.org/uniprot/F1R9X0", "type": "external" } ], "mass": 69814.0, "length": 644, "protein_name": "Solute carrier family 7, member 3", "gene_name": "slc7a3a", "organism": "Zebrafish", "refseq_name": "solute carrier family 7, member 3", "refseq_ac": [ { "id": "NP_001007330", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007330", "type": "external" } ], "gene_names_uniprotkb": "slc7a3a; slc7a3; wu:fc11h09; zgc:92563", "gene_names_refseq": "slc7a3a; slc7a3; wu:fc11h09; zgc:92563", "protein_names_uniprotkb": "Solute carrier family 7, member 3", "protein_names_refseq": "solute carrier family 7 (cationic amino acid transporter, y+ system), member 3a; solute carrier family 7 (cationic amino acid transporter, y+ system), member 3; solute carrier family 7, member 3", "tax_id": 7955, "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); lipid storage disease (Disease Ontology:DOID:9455)", "pathway": " (dre:492363); (R-DRE-352230)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12618376;25130427", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC085672.1, GDQH01000372.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On May 7, 2009 this sequence version replaced NP_001007330.1., [RefSeq]; Null mutants have hepatic steatosis, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N377", "ec_number_list": [], "go_molecular_function": "GO:0015171 amino acid transmembrane transporter activity;GO:0061459 L-arginine transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0006641 triglyceride metabolic process;GO:0006865 amino acid transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1R9X0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RAK7-1", "uniprot_id": [ { "id": "F1RAK7_DANRE", "url": "https://www.uniprot.org/uniprot/F1RAK7", "type": "external" } ], "mass": 49559.0, "length": 432, "protein_name": "Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3", "gene_name": "gcnt3", "organism": "Zebrafish", "refseq_name": "beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3", "refseq_ac": [ { "id": "XP_002666963", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002666963", "type": "external" } ], "gene_names_uniprotkb": "gcnt3", "gene_names_refseq": "gcnt3", "protein_names_uniprotkb": "Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3; 2.4.1.102; 2.4.1.148; 2.4.1.150; C2GnT-mucin type", "protein_names_refseq": "beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3", "tax_id": 7955, "disease": "", "pathway": " (dre:100332076); (R-DRE-913709)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Also has I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RMV3", "ec_number_list": [ { "id": "2.4.1.102", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.102", "type": "external" }, { "id": "2.4.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.150", "type": "external" }, { "id": "2.4.1.148", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.148", "type": "external" } ], "go_molecular_function": "GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity;GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity;GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity;GO:0008375 acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1RAK7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RAM9-1", "uniprot_id": [ { "id": "F1RAM9_DANRE", "url": "https://www.uniprot.org/uniprot/F1RAM9", "type": "external" } ], "mass": 24442.0, "length": 216, "protein_name": "Transmembrane emp24 domain-containing protein 7", "gene_name": "tmed7", "organism": "Zebrafish", "refseq_name": "transmembrane emp24 domain-containing protein 7 precursor", "refseq_ac": [ { "id": "NP_001300637", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001300637", "type": "external" } ], "gene_names_uniprotkb": "tmed7; zgc:76996", "gene_names_refseq": "tmed7; zgc:76996", "protein_names_uniprotkb": "Transmembrane emp24 domain-containing protein 7; p24 family protein gamma-3; p27", "protein_names_refseq": "p24 gamma 3; transmembrane emp24 domain-containing protein 7 precursor; transmembrane emp24 protein transport domain containing 7", "tax_id": 7955, "disease": "", "pathway": " (dre:405848); (R-DRE-6807878); (R-DRE-6811434)", "pathway_count": 3, "publication_count": 7, "publication_id_list": "17372010;19429673;23457027;26469318;27189481;28252024;28658311", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395015.13461.1, SRR32588718.25266072.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476745, SAMEA4476773 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CN505306.1, JBMGRA010000008.1, EH456276.1 and EH482012.1. On Aug 27, 2015 this sequence version replaced XP_005172485.1. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, 3, and 4 encode the same protein., [RefSeq]; Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Appears to play a role in the biosynthesis of secreted cargo including processing and post-translational modifications., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7V0D0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0030134 COPII-coated ER to Golgi transport vesicle;GO:0005789 endoplasmic reticulum membrane;GO:0012507 ER to Golgi transport vesicle membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "F1RAM9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RAW8-1", "uniprot_id": [ { "id": "F1RAW8_DANRE", "url": "https://www.uniprot.org/uniprot/F1RAW8", "type": "external" } ], "mass": 66016.0, "length": 590, "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ash2l", "organism": "Zebrafish", "refseq_name": "set1/Ash2 histone methyltransferase complex subunit ASH2", "refseq_ac": [ { "id": "NP_001103575", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103575", "type": "external" } ], "gene_names_uniprotkb": "ash2l; fb34c06; fe38b04; fi20h02; wu:fb34c06; wu:fe38b04; wu:fi20h02; zgc:171444", "gene_names_refseq": "ash2l; fb34c06; fe38b04; fi20h02; wu:fb34c06; wu:fe38b04; wu:fi20h02; zgc:171444", "protein_names_uniprotkb": "Set1/Ash2 histone methyltransferase complex subunit ASH2; ASH2-like protein", "protein_names_refseq": "set1/Ash2 histone methyltransferase complex subunit ASH2", "tax_id": 7955, "disease": "", "pathway": " (dre:558193); (R-DRE-201722)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "24240475;24873830;26469318;27009152;30458291;30944473", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01001676.1, GDQQ01005666.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505373 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000010.1, CT698001.2, CT627023.2, CT679794.2 and CT679795.2. On Mar 11, 2009 this sequence version replaced NP_001103575.1., [RefSeq]; Transcriptional regulator. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May play a role in hematopoiesis. In association with RBBP5 and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NG69", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding;GO:0008168 methyltransferase activity;GO:0003677 DNA binding", "go_cellular_component": "GO:0048188 Set1C/COMPASS complex;GO:0071339 MLL1 complex", "go_biological_process": "GO:0060319 primitive erythrocyte differentiation;GO:0010557 positive regulation of macromolecule biosynthetic process;GO:0006351 DNA-templated transcription;GO:0006325 chromatin organization;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F1RAW8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RAX8-1", "uniprot_id": [ { "id": "COQ6_DANRE", "url": "https://www.uniprot.org/uniprot/F1RAX8", "type": "external" } ], "mass": 52999.0, "length": 484, "protein_name": "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial", "gene_name": "coq6", "organism": "Zebrafish", "refseq_name": "ubiquinone biosynthesis monooxygenase COQ6, mitochondrial", "refseq_ac": [ { "id": "NP_001038869", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038869", "type": "external" } ], "gene_names_uniprotkb": "coq6; COQ6; zgc:153379", "gene_names_refseq": "coq6; zgc:153379", "protein_names_uniprotkb": "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; 1.14.15.45; 1.14.15.46; 2-methoxy-6-polyprenolphenol 4-hydroxylase; Coenzyme Q10 monooxygenase 6", "protein_names_refseq": "2-methoxy-6-polyprenolphenol 4-hydroxylase; coenzyme Q10 monooxygenase 6; coenzyme Q6 homolog, monooxygenase; ubiquinone biosynthesis monooxygenase COQ6, mitochondrial", "tax_id": 7955, "disease": "primary coenzyme Q10 deficiency 6 (Disease Ontology:DOID:0070243); nephrotic syndrome (Disease Ontology:DOID:1184); schwannomatosis (Disease Ontology:DOID:3204)", "pathway": " (dre:751691); (R-DRE-2142789)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC122260.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC122260.1., [RefSeq]; FAD-dependent monooxygenase required for two non-consecutive steps during ubiquinone biosynthesis. Required for the C5-ring hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 4-hydroxy-3-(all-trans-polyprenyl)benzoic acid to 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoic acid. Also acts downstream of coq4, for the C1-hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 2-methoxy-6-(all-trans-polyprenyl)phenol to 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol. The electrons required for the hydroxylation reaction are funneled indirectly to coq6 from NADPH via a ferredoxin/ferredoxin reductase system., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0P462", "ec_number_list": [ { "id": "2.7.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.-.-", "type": "external" }, { "id": "4.1.1.130", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.130", "type": "external" }, { "id": "1.14.15.45", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.15.45", "type": "external" }, { "id": "1.14.15.46", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.15.46", "type": "external" }, { "id": "2.1.1.201", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.201", "type": "external" } ], "go_molecular_function": "GO:0071949 FAD binding;GO:0016491 oxidoreductase activity;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0106364 4-hydroxy-3-all-trans-polyprenylbenzoate oxygenase activity;GO:0120538 2-methoxy-6-polyprenolphenol 4-hydroxylase activity", "go_cellular_component": "GO:0031314 extrinsic component of mitochondrial inner membrane;GO:0005739 mitochondrion;GO:0005794 Golgi apparatus;GO:0042995 cell projection", "go_biological_process": "GO:0006744 ubiquinone biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RAX8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0P3Z2-1", "uniprot_id": [ { "id": "PTER_DANRE", "url": "https://www.uniprot.org/uniprot/Q0P3Z2", "type": "external" } ], "mass": 39178.0, "length": 349, "protein_name": "N-acetyltaurine hydrolase", "gene_name": "pter", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "pter; si:ch211-261f3.2; zgc:153666", "gene_names_refseq": "", "protein_names_uniprotkb": "N-acetyltaurine hydrolase; 3.1.-.-; Phosphotriesterase-related protein", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:751664)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "23427857;23594743;26469318;28252024;30728369;36403304", "class_list": "", "function": "N-acetyltaurine hydrolase that catalyzes the hydrolysis of N-acetyltaurine into taurine and acetate. PTER also acts on other N-acetyl amino acids (Met, Ile, Leu, Val) and N-propionyltaurine, but at lower rates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A2BII3", "ec_number_list": [ { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0141215 N-acetyltaurine hydrolase activity;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0032098 regulation of appetite;GO:0019530 taurine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q0P3Z2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RBY0-1", "uniprot_id": [ { "id": "F1RBY0_DANRE", "url": "https://www.uniprot.org/uniprot/F1RBY0", "type": "external" } ], "mass": 67490.0, "length": 625, "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "mindy2", "organism": "Zebrafish", "refseq_name": "ubiquitin carboxyl-terminal hydrolase MINDY-2", "refseq_ac": [ { "id": "NP_001004517", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004517", "type": "external" } ], "gene_names_uniprotkb": "mindy2; fam63b; si:busm1-199m19.4; si:dz199m19.4", "gene_names_refseq": "fam63b; mindy2; si:busm1-199m19.4; si:dz199m19.4", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12", "protein_names_refseq": "family with sequence similarity 63, member B; ubiquitin carboxyl-terminal hydrolase MINDY-2", "tax_id": 7955, "disease": "", "pathway": " (dre:570359)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "26469318;27189481;28252024", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395039.1043046.1, SRR32588715.793651.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505380, SAMEA3505382 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On May 19, 2016 this sequence version replaced XP_698926.5. Sequence Note:., [RefSeq]; Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N1U2", "ec_number_list": [], "go_molecular_function": "GO:0036435 K48-linked polyubiquitin modification-dependent protein binding;GO:0016807 cysteine-type carboxypeptidase activity;GO:0004843 cysteine-type deubiquitinase activity;GO:1990380 K48-linked deubiquitinase activity;GO:0140934 histone deubiquitinase activity", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1RBY0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RCE7-1", "uniprot_id": [ { "id": "MTFR1_DANRE", "url": "https://www.uniprot.org/uniprot/F1RCE7", "type": "external" } ], "mass": 35169.0, "length": 318, "protein_name": "Mitochondrial fission regulator 1", "gene_name": "mtfr1", "organism": "Zebrafish", "refseq_name": "mitochondrial fission regulator 1", "refseq_ac": [ { "id": "NP_001008578", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008578", "type": "external" } ], "gene_names_uniprotkb": "mtfr1; zgc:92267", "gene_names_refseq": "cb1054; mtfr1; sb:cb669; wu:fb82e05; wu:fk53d11; zgc:92267", "protein_names_uniprotkb": "Mitochondrial fission regulator 1", "protein_names_refseq": "mitochondrial fission regulator 1", "tax_id": 7955, "disease": "", "pathway": " (dre:494035)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC086966.1, CK027988.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505381, SAMEA3505385 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC086966.1., [RefSeq]; May play a role in mitochondrial aerobic respiration. May also regulate mitochondrial organization and fission (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "B5RHZ5;F1R397;Q5PQY8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0007005 mitochondrion organization;GO:0000266 mitochondrial fission;GO:0009060 aerobic respiration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RCE7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RCL8-1", "uniprot_id": [ { "id": "F1RCL8_DANRE", "url": "https://www.uniprot.org/uniprot/F1RCL8", "type": "external" } ], "mass": 196732.0, "length": 1796, "protein_name": "BCL-6 corepressor isoform X1", "gene_name": "bcor", "organism": "Zebrafish", "refseq_name": "BCL-6 corepressor isoform X1", "refseq_ac": [ { "id": "XP_005174000", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174000", "type": "external" } ], "gene_names_uniprotkb": "bcor", "gene_names_refseq": "bcor", "protein_names_uniprotkb": "BCL-6 corepressor isoform X1", "protein_names_refseq": "BCL-6 corepressor isoform X1", "tax_id": 7955, "disease": "syndromic microphthalmia 1 (Disease Ontology:DOID:0111799); syndromic microphthalmia 2 (Disease Ontology:DOID:0111809); stomach cancer (Disease Ontology:DOID:10534); proliferative diabetic retinopathy (Disease Ontology:DOID:13207); dental caries (Disease Ontology:DOID:216); stomach carcinoma (Disease Ontology:DOID:5517); cataract (Disease Ontology:DOID:83); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BLL2", "ec_number_list": [], "go_molecular_function": "GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0060042 retina morphogenesis in camera-type eye;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0021915 neural tube development;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1RCL8-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RCT9-1", "uniprot_id": [ { "id": "F1RCT9_DANRE", "url": "https://www.uniprot.org/uniprot/F1RCT9", "type": "external" } ], "mass": 30476.0, "length": 280, "protein_name": "Paired mesoderm homeobox protein 2A", "gene_name": "phox2a", "organism": "Zebrafish", "refseq_name": "paired mesoderm homeobox protein 2A", "refseq_ac": [ { "id": "NP_996953", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996953", "type": "external" } ], "gene_names_uniprotkb": "phox2a; arix; sou; zgc:77364", "gene_names_refseq": "arix; phox2a; sou; zgc:77364", "protein_names_uniprotkb": "Paired mesoderm homeobox protein 2A", "protein_names_refseq": "aristaless homeobox; paired mesoderm homeobox protein 2A; soulless", "tax_id": 7955, "disease": "congenital fibrosis of the extraocular muscles 2 (Disease Ontology:DOID:0081016); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dre:404602)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10191060;10595509;11948255;12091300;12736211;29257950;29355522;32533114;36117635;37968389", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395062.599042.1, SRR26395062.1850734.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505375 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On or before Apr 17, 2018 this sequence version replaced XP_005169693.1, NP_996953.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BHH1", "ec_number_list": [], "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007420 brain development;GO:0048666 neuron development;GO:0003358 noradrenergic neuron development", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1RCT9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RD06-1", "uniprot_id": [ { "id": "F1RD06_DANRE", "url": "https://www.uniprot.org/uniprot/F1RD06", "type": "external" } ], "mass": 50151.0, "length": 451, "protein_name": "Synaptotagmin-11a", "gene_name": "syt11a", "organism": "Zebrafish", "refseq_name": "synaptotagmin-11a", "refseq_ac": [ { "id": "NP_998625", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998625", "type": "external" } ], "gene_names_uniprotkb": "syt11a; fc52d10; fi68d01; syt11; wu:fc52d10; wu:fi68d01; zgc:55556", "gene_names_refseq": "fc52d10; fi68d01; syt11a; syt11; wu:fc52d10; wu:fi68d01; zgc:55556", "protein_names_uniprotkb": "Synaptotagmin-11a", "protein_names_refseq": "synaptotagmin XI; synaptotagmin-11a", "tax_id": 7955, "disease": "type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dre:406769); (R-DRE-8856825)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "15238157;17672888;20078875;21669877;26469318;28252024;35710785;38765140;39147780", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01024689.1, BC044424.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On Jun 26, 2009 this sequence version replaced NP_998625.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PJG8", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0005544 calcium-dependent phospholipid binding;GO:0000149 SNARE binding;GO:0061891 calcium ion sensor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0045202 synapse;GO:0030659 cytoplasmic vesicle membrane;GO:0070382 exocytic vesicle", "go_biological_process": "GO:0016192 vesicle-mediated transport;GO:0017158 regulation of calcium ion-dependent exocytosis;GO:0006906 vesicle fusion;GO:1903531 negative regulation of secretion by cell;GO:0099502 calcium-dependent activation of synaptic vesicle fusion", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "F1RD06-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RDZ8-1", "uniprot_id": [ { "id": "F1RDZ8_DANRE", "url": "https://www.uniprot.org/uniprot/F1RDZ8", "type": "external" } ], "mass": 56305.0, "length": 498, "protein_name": "Nicotinamide phosphoribosyltransferase", "gene_name": "nampt2", "organism": "Zebrafish", "refseq_name": "nicotinamide phosphoribosyltransferase 2", "refseq_ac": [ { "id": "NP_997833", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997833", "type": "external" } ], "gene_names_uniprotkb": "nampt2; im:7051384; namptb; wu:fc21g12; wu:fc27h03; wu:fd15d03; zgc:55764", "gene_names_refseq": "im:7051384; nampt2; namptb; wu:fc21g12; wu:fc27h03; wu:fd15d03; zgc:55764", "protein_names_uniprotkb": "Nicotinamide phosphoribosyltransferase; 2.4.2.12; NAmPRTase", "protein_names_refseq": "nicotinamide phosphoribosyltransferase 2; nicotinamide phosphoribosyltransferase b; pre-B-cell colony-enhancing factor", "tax_id": 7955, "disease": "transient cerebral ischemia (Disease Ontology:DOID:224); coronary artery disease (Disease Ontology:DOID:3393); carotid artery disease (Disease Ontology:DOID:3407); pulmonary hypertension (Disease Ontology:DOID:6432); psoriasis (Disease Ontology:DOID:8893); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:324211)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "23091147;24683187;26469318;30530669;33568815;34748530;35697381;38685093", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC044476.1, GDQH01004919.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1, EH551317.1 and EH572450.1. On Jan 28, 2016 this sequence version replaced NP_997833.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PFF2", "ec_number_list": [ { "id": "2.4.2.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.12", "type": "external" } ], "go_molecular_function": "GO:0047280 nicotinamide phosphoribosyltransferase activity;GO:0005125 cytokine activity;GO:0016757 glycosyltransferase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0009435 NAD+ biosynthetic process;GO:0032922 circadian regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "F1RDZ8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1REL9-1", "uniprot_id": [ { "id": "F1REL9_DANRE", "url": "https://www.uniprot.org/uniprot/F1REL9", "type": "external" } ], "mass": 197676.0, "length": 1767, "protein_name": "Laminin subunit beta-1b precursor", "gene_name": "lamb1b", "organism": "Zebrafish", "refseq_name": "laminin subunit beta-1b precursor", "refseq_ac": [ { "id": "NP_001264059", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264059", "type": "external" } ], "gene_names_uniprotkb": "lamb1b; si:dkey-183c16.5", "gene_names_refseq": "lamb1b; si:dkey-183c16.5", "protein_names_uniprotkb": "Laminin subunit beta-1b precursor", "protein_names_refseq": "laminin subunit beta-1b precursor", "tax_id": 7955, "disease": "leukoencephalopathy with variable cortical brain malformations and/or hydrocephalus (Disease Ontology:DOID:0112230); autistic disorder (Disease Ontology:DOID:12849)", "pathway": " (dre:556605)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "21246659;24942242;26305099;30082271;31034836;32379754;34463754;34568948;36142434;37884489", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01007016.1, GFIL01014217.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476730, SAMEA4476731 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000004.1. On Mar 9, 2013 this sequence version replaced XP_684538.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NZC1", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding", "go_cellular_component": "GO:0043256 laminin complex", "go_biological_process": "GO:0016477 cell migration;GO:0009887 animal organ morphogenesis;GO:0034446 substrate adhesion-dependent cell spreading;GO:0007411 axon guidance;GO:0009888 tissue development", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1REL9-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1REP3-1", "uniprot_id": [ { "id": "F1REP3_DANRE", "url": "https://www.uniprot.org/uniprot/F1REP3", "type": "external" } ], "mass": 31433.0, "length": 280, "protein_name": "Metalloendopeptidase", "gene_name": "npsn", "organism": "Zebrafish", "refseq_name": "nephrosin isoform 2 precursor", "refseq_ac": [ { "id": "NP_991319", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_991319", "type": "external" } ], "gene_names_uniprotkb": "npsn; npsnl; zgc:110470; zgc:152831", "gene_names_refseq": "npsnl; npsn; zgc:110470; zgc:152831", "protein_names_uniprotkb": "Metalloendopeptidase; 3.4.24.-", "protein_names_refseq": "ZC6AST2; nephrosin isoform 2 precursor", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 10, "publication_id_list": "15520368;17016731;18641354;21901140;23714367;27974754;28835569;29378332;33434583;36300552", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AF498291.1, CN015480.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505391, SAMEA3505392 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Feb 4, 2016 this sequence version replaced NP_991319.1. Transcript Variant: This variant (2) lacks the 3' terminal exon and extends past a splice site that is used in variant 1. This results in a novel 3' coding region and 3' UTR, compared to variant 1. It encodes isoform 2 which is longer and has a distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference genome strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Findings provide evidence that Npsn is crucial for host defence against bacterial infection, and that npsn-deficient and overexpressing zebrafish might serve as effective models of in vivo innate immunity., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PHD0", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1REP3-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F2Z4T6-1", "uniprot_id": [ { "id": "F2Z4T6_DANRE", "url": "https://www.uniprot.org/uniprot/F2Z4T6", "type": "external" } ], "mass": 11340.0, "length": 101, "protein_name": "Ubiquitin-related modifier 1", "gene_name": "urm1", "organism": "Zebrafish", "refseq_name": "ubiquitin-related modifier 1", "refseq_ac": [ { "id": "NP_001315021", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315021", "type": "external" } ], "gene_names_uniprotkb": "urm1; URM1; si:dkeyp-68f6.2", "gene_names_refseq": "si:dkeyp-68f6.2; urm1", "protein_names_uniprotkb": "Ubiquitin-related modifier 1", "protein_names_refseq": "ubiquitin-related modifier 1", "tax_id": 7955, "disease": "", "pathway": " (dre:558120)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "18335061;26881892;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH577060.1, EH555959.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000010.1. On Jun 25, 2025 this sequence version replaced NP_001315021.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P9X0", "ec_number_list": [], "go_molecular_function": "GO:0031386 protein tag activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0034227 tRNA thio-modification;GO:0002098 tRNA wobble uridine modification;GO:0032447 protein urmylation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F2Z4T6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F2Z4V3-1", "uniprot_id": [ { "id": "F2Z4V3_DANRE", "url": "https://www.uniprot.org/uniprot/F2Z4V3", "type": "external" } ], "mass": 99300.0, "length": 872, "protein_name": "Prickle-like protein 1b", "gene_name": "prickle1b", "organism": "Zebrafish", "refseq_name": "prickle-like protein 1b", "refseq_ac": [ { "id": "NP_001025269", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025269", "type": "external" } ], "gene_names_uniprotkb": "prickle1b; fb98c11; si:ch211-155a11.1; wu:fb98c11", "gene_names_refseq": "fb98c11; prickle1b; si:ch211-155a11.1; wu:fb98c11", "protein_names_uniprotkb": "Prickle-like protein 1b", "protein_names_refseq": "pk1b; prickle homolog 1 b; prickle-like protein 1b", "tax_id": 7955, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); autosomal recessive Robinow syndrome (Disease Ontology:DOID:0060764); progressive myoclonus epilepsy 1B (Disease Ontology:DOID:0111448); velocardiofacial syndrome (Disease Ontology:DOID:12583)", "pathway": " (dre:556148); (R-DRE-4608870)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "16603149;17651720;19937772;20503357;21521740;27955617;30721665;31680844;31748748;32319426", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395028.757633.1, SRR26395017.961106.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EB928759.1, JBMGRA010000004.1 and AI588252.1. On Aug 6, 2005 this sequence version replaced XP_683975.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Hoxb1a target Prickle1b functions cell-autonomously to control facial neuron migration, a single aspect of r4 identity., [RefSeq, PubMed]; Our data suggest that Pk1b function may be required to integrate the multiple migratory cues received by the neurons into polarization instructions for proper posterior movement., [RefSeq, PubMed]; Show that anterior hindbrain (r2/r3) motor neuron migration appears to be independent of vangl2 and pk1b functions, and suggest that multiple mechanisms regulate motor neuron migration along the anterior-posterior axis of the zebrafish hindbrain, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N760", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0012505 endomembrane system", "go_biological_process": "GO:0021754 facial nucleus development;GO:0021934 hindbrain tangential cell migration;GO:0097475 motor neuron migration;GO:0001764 neuron migration;GO:0001755 neural crest cell migration", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F2Z4V3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F2Z4V7-1", "uniprot_id": [ { "id": "F2Z4V7_DANRE", "url": "https://www.uniprot.org/uniprot/F2Z4V7", "type": "external" } ], "mass": 59444.0, "length": 536, "protein_name": "Solute carrier family 43 member 1a", "gene_name": "slc43a1a", "organism": "Zebrafish", "refseq_name": "solute carrier family 43 member 1a", "refseq_ac": [ { "id": "NP_001314915", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314915", "type": "external" } ], "gene_names_uniprotkb": "slc43a1a; fi47a12; lat3a; slc43a1; wu:fi47a12; zgc:55850", "gene_names_refseq": "fi47a12; lat3a; slc43a1a; slc43a1; wu:fi47a12; zgc:55850", "protein_names_uniprotkb": "Solute carrier family 43 member 1a", "protein_names_refseq": "solute carrier family 43 (amino acid system L transporter), member 1a; solute carrier family 43 member 1a", "tax_id": 7955, "disease": "", "pathway": " (dre:334395)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "17961207;19443642;23515471;25872869;29844341", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588729.25109606.1, SRR26395039.36778.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Jun 25, 2025 this sequence version replaced NP_001314915.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; LAT3 may play a crucial role in the development and maintenance of podocyte structure and function by regulating protein synthesis and the actin cytoskeleton [LAT3]., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P9P9", "ec_number_list": [], "go_molecular_function": "GO:0015179 L-amino acid transmembrane transporter activity;GO:0015175 neutral L-amino acid transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0015804 neutral amino acid transport;GO:0072015 podocyte development", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F2Z4V7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6NJE2-1", "uniprot_id": [ { "id": "F6NJE2_DANRE", "url": "https://www.uniprot.org/uniprot/F6NJE2", "type": "external" } ], "mass": 76472.0, "length": 686, "protein_name": "Interleukin-1 receptor-associated kinase 1 isoform X1; Interleukin-1 receptor-associated kinase 1 isoform X2", "gene_name": "irak1", "organism": "Zebrafish", "refseq_name": "interleukin-1 receptor-associated kinase 1 isoform X1", "refseq_ac": [ { "id": "XP_005166760", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166760", "type": "external" } ], "gene_names_uniprotkb": "irak1", "gene_names_refseq": "irak1", "protein_names_uniprotkb": "Interleukin-1 receptor-associated kinase 1 isoform X1; Interleukin-1 receptor-associated kinase 1 isoform X2", "protein_names_refseq": "interleukin-1 receptor-associated kinase 1 isoform X1", "tax_id": 7955, "disease": "diffuse scleroderma (Disease Ontology:DOID:1580); squamous cell carcinoma (Disease Ontology:DOID:1749); asthma (Disease Ontology:DOID:2841); pulmonary tuberculosis (Disease Ontology:DOID:2957); primary immunodeficiency disease (Disease Ontology:DOID:612); ankylosing spondylitis (Disease Ontology:DOID:7147); psoriasis (Disease Ontology:DOID:8893); psoriatic arthritis (Disease Ontology:DOID:9008)", "pathway": " (dre:569226); (R-DRE-209543); (R-DRE-209560); (R-DRE-445989); (R-DRE-450302); (R-DRE-450321); (R-DRE-9020702); (R-DRE-937039); (R-DRE-937042); (R-DRE-937072); (R-DRE-975144); (R-DRE-975163)", "pathway_count": 12, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BE72", "ec_number_list": [], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0016301 kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0070498 interleukin-1-mediated signaling pathway;GO:0035556 intracellular signal transduction;GO:0045087 innate immune response;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0031663 lipopolysaccharide-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F6NJE2-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6NLH0-1", "uniprot_id": [ { "id": "F6NLH0_DANRE", "url": "https://www.uniprot.org/uniprot/F6NLH0", "type": "external" } ], "mass": 126875.0, "length": 1133, "protein_name": "Hermansky-Pudlak syndrome 5 protein homolog", "gene_name": "hps5", "organism": "Zebrafish", "refseq_name": "BLOC-2 complex member HPS5", "refseq_ac": [ { "id": "NP_001083008", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001083008", "type": "external" } ], "gene_names_uniprotkb": "hps5; zgc:162420", "gene_names_refseq": "hps5; zgc:162420", "protein_names_uniprotkb": "Hermansky-Pudlak syndrome 5 protein homolog", "protein_names_refseq": "BLOC-2 complex member HPS5; Hermansky-Pudlak syndrome 5; snow white; snw", "tax_id": 7955, "disease": "Hermansky-Pudlak syndrome 5 (Disease Ontology:DOID:0060543); platelet storage pool deficiency (Disease Ontology:DOID:2223); Hermansky-Pudlak syndrome (Disease Ontology:DOID:3753); proteinuria (Disease Ontology:DOID:576)", "pathway": " (dre:100037388)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "23639161;23893484;26469318;27189481;31776394;9007234", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC121196.1, GDQH01003015.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On Aug 26, 2025 this sequence version replaced NP_001083008.2., [RefSeq]; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins., [UniProtKB, UniProtKB]; The snw/hps5I76N mutant provides a valuable resource for structure-function analyses of Hps5 and enables further elucidation of the molecular and cellular mechanisms underlying HPS., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NEE3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0031084 BLOC-2 complex", "go_biological_process": "GO:0043473 pigmentation;GO:0048066 developmental pigmentation;GO:0030903 notochord development;GO:0048076 regulation of compound eye pigmentation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F6NLH0-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6NLN8-1", "uniprot_id": [ { "id": "F6NLN8_DANRE", "url": "https://www.uniprot.org/uniprot/F6NLN8", "type": "external" } ], "mass": 94281.0, "length": 816, "protein_name": "Toll-like receptor 4", "gene_name": "tlr4al", "organism": "Zebrafish", "refseq_name": "toll-like receptor 4a, like", "refseq_ac": [ { "id": "NP_001315534", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315534", "type": "external" } ], "gene_names_uniprotkb": "tlr4al; tlr4ba", "gene_names_refseq": "tlr4al; tlr4ba", "protein_names_uniprotkb": "Toll-like receptor 4", "protein_names_refseq": "toll-like receptor 4a, like", "tax_id": 7955, "disease": "", "pathway": " (dre:795671)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "20153437;20470893;24811009;25548877;28592872;34007309;34305858;34600663;35700135;37061125", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588719.8252465.1, SRR32588729.25670055.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA4476728, SAMEA4476750 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CM124819.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P458", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0001530 lipopolysaccharide binding;GO:0001875 lipopolysaccharide immune receptor activity", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0001726 ruffle;GO:0046696 lipopolysaccharide receptor complex", "go_biological_process": "GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0050829 defense response to Gram-negative bacterium;GO:0034142 toll-like receptor 4 signaling pathway;GO:0002755 MyD88-dependent toll-like receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F6NLN8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6NMA7-1", "uniprot_id": [ { "id": "F6NMA7_DANRE", "url": "https://www.uniprot.org/uniprot/F6NMA7", "type": "external" } ], "mass": 25280.0, "length": 223, "protein_name": "Ras-related protein Rab-3", "gene_name": "rab3da", "organism": "Zebrafish", "refseq_name": "RAB3D, member RAS oncogene family, a", "refseq_ac": [ { "id": "NP_001139069", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139069", "type": "external" } ], "gene_names_uniprotkb": "rab3da; fi17a03; rab3d; wu:fi17a03", "gene_names_refseq": "fi17a03; rab3da; rab3d; wu:fi17a03", "protein_names_uniprotkb": "Ras-related protein Rab-3", "protein_names_refseq": "RAB3D, member RAS oncogene family, a", "tax_id": 7955, "disease": "", "pathway": " (dre:567288); (R-DRE-6798695); (R-DRE-8873719)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "27189481;28252024;28396820;30504219", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: CT731078.2, CT715953.2 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000001.1. On Mar 5, 2009 this sequence version replaced XP_695672.2., [RefSeq]; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB3D may be involved in the insulin-induced exocytosis of GLUT4-containing vesicles in adipocytes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NTD3", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0031489 myosin V binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0030141 secretory granule;GO:0008021 synaptic vesicle", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006887 exocytosis;GO:0017157 regulation of exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F6NMA7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6NMN3-1", "uniprot_id": [ { "id": "F6NMN3_DANRE", "url": "https://www.uniprot.org/uniprot/F6NMN3", "type": "external" } ], "mass": 56306.0, "length": 489, "protein_name": "Serine/threonine-protein phosphatase", "gene_name": "ppp5c", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ppp5c; fc83f08; im:7146608; wu:fc83f08; zgc:110801", "gene_names_refseq": "", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase; 3.1.3.16", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (R-DRE-5675221); (R-DRE-5693565); (R-DRE-8939211)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B3I0", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F6NMN3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6NN04-1", "uniprot_id": [ { "id": "F6NN04_DANRE", "url": "https://www.uniprot.org/uniprot/F6NN04", "type": "external" } ], "mass": 68233.0, "length": 614, "protein_name": "Transporter", "gene_name": "slc6a14", "organism": "Zebrafish", "refseq_name": "sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)", "refseq_ac": [ { "id": "NP_001313379", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313379", "type": "external" } ], "gene_names_uniprotkb": "slc6a14", "gene_names_refseq": "slc6a14", "protein_names_uniprotkb": "Transporter", "protein_names_refseq": "sodium- and chloride-dependent neutral and basic amino acid transporter B(0+); solute carrier family 6 (amino acid transporter), member 14", "tax_id": 7955, "disease": "osteoporosis (Disease Ontology:DOID:11476); male infertility (Disease Ontology:DOID:12336); exocrine pancreatic insufficiency (Disease Ontology:DOID:13316); cystic fibrosis (Disease Ontology:DOID:1485); gastrointestinal system disease (Disease Ontology:DOID:77); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:100150665); (R-DRE-352230); (R-DRE-442660)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "25805459;26469318;29042681", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC117616.1, GDQH01030125.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On May 18, 2016 this sequence version replaced XP_001923596.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P905", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0022858 alanine transmembrane transporter activity;GO:1901235 (R)-carnitine transmembrane transporter activity;GO:0001761 beta-alanine transmembrane transporter activity;GO:0015374 neutral, basic amino acid:sodium:chloride symporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0035725 sodium ion transmembrane transport;GO:1903804 glycine import across plasma membrane;GO:1902270 (R)-carnitine transmembrane transport;GO:0001762 beta-alanine transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F6NN04-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6NQL8-1", "uniprot_id": [ { "id": "F6NQL8_DANRE", "url": "https://www.uniprot.org/uniprot/F6NQL8", "type": "external" } ], "mass": 72772.0, "length": 639, "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "hcn3", "organism": "Zebrafish", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": [ { "id": "XP_689197", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689197", "type": "external" } ], "gene_names_uniprotkb": "hcn3", "gene_names_refseq": "hcn3", "protein_names_uniprotkb": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "protein_names_refseq": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "tax_id": 7955, "disease": "", "pathway": " (R-DRE-1296061)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TDP4;A0AC58I023", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.2", "type": "external" } ], "go_molecular_function": "GO:0005272 sodium channel activity;GO:0005249 voltage-gated potassium channel activity;GO:0030552 cAMP binding", "go_cellular_component": "GO:0030424 axon;GO:0030425 dendrite;GO:0098855 HCN channel complex", "go_biological_process": "GO:0035725 sodium ion transmembrane transport;GO:0003254 regulation of membrane depolarization;GO:0071805 potassium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F6NQL8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6NSV0-1", "uniprot_id": [ { "id": "F6NSV0_DANRE", "url": "https://www.uniprot.org/uniprot/F6NSV0", "type": "external" } ], "mass": 29149.0, "length": 257, "protein_name": "Fibroblast growth factor", "gene_name": "fgf13b", "organism": "Zebrafish", "refseq_name": "fibroblast growth factor 13b isoform 1", "refseq_ac": [ { "id": "NP_001315421", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315421", "type": "external" } ], "gene_names_uniprotkb": "fgf13b; fgf13l; zgc:76868", "gene_names_refseq": "fgf13b; fgf13l; zgc:76868", "protein_names_uniprotkb": "Fibroblast growth factor; FGF", "protein_names_refseq": "fibroblast growth factor 13, like; fibroblast growth factor 13b isoform 1", "tax_id": 7955, "disease": "non-syndromic X-linked intellectual disability (Disease Ontology:DOID:0050776); developmental and epileptic encephalopathy 90 (Disease Ontology:DOID:0070381); intellectual disability (Disease Ontology:DOID:1059)", "pathway": " (dre:403003)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "18554177;18565740;24204792;25420467;26469318;27704300;28096348;28867147;36841347;38791872", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588729.35612884.1, SRR32588719.12139131.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505373, SAMEA3505374 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000010.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P4W4", "ec_number_list": [], "go_molecular_function": "GO:0017080 sodium channel regulator activity;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0022008 neurogenesis", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F6NSV0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6NVH9-1", "uniprot_id": [ { "id": "NIPS1_DANRE", "url": "https://www.uniprot.org/uniprot/F6NVH9", "type": "external" } ], "mass": 32873.0, "length": 279, "protein_name": "Protein NipSnap homolog 1", "gene_name": "nipsnap1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "nipsnap1; zgc:153339", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein NipSnap homolog 1; NipSnap1", "protein_names_refseq": "", "tax_id": 7955, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (dre:30231)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;30982665", "class_list": "", "function": "Protein involved in mitophagy (PubMed:30982665). Accumulates on the mitochondria surface in response to mitochondrial depolarization and acts as a 'eat me' signal by recruiting proteins involved in selective autophagy (By similarity)., [UniProtKB, UniProtKB, PubMed]; Protein involved in mitophagy. Accumulates on the mitochondria surface in response to mitochondrial depolarization and acts as a 'eat me' signal by recruiting proteins involved in selective autophagy., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N1TSJ0", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0000423 mitophagy", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F6NVH9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6P0J3-1", "uniprot_id": [ { "id": "F6P0J3_DANRE", "url": "https://www.uniprot.org/uniprot/F6P0J3", "type": "external" } ], "mass": 52903.0, "length": 454, "protein_name": "Calsequestrin", "gene_name": "casq1b", "organism": "Zebrafish", "refseq_name": "calsequestrin-1b isoform X1", "refseq_ac": [ { "id": "XP_005166685", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166685", "type": "external" } ], "gene_names_uniprotkb": "casq1b; zgc:154027", "gene_names_refseq": "casq1b; zgc:154027", "protein_names_uniprotkb": "Calsequestrin", "protein_names_refseq": "calsequestrin-1b isoform X1", "tax_id": 7955, "disease": "type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BE26", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0030018 Z disc;GO:0033018 sarcoplasmic reticulum lumen", "go_biological_process": "GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F6P0J3-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6P1A9-1", "uniprot_id": [ { "id": "F6P1A9_DANRE", "url": "https://www.uniprot.org/uniprot/F6P1A9", "type": "external" } ], "mass": 30612.0, "length": 266, "protein_name": "Ubiquitin thioesterase", "gene_name": "otub1b", "organism": "Zebrafish", "refseq_name": "ubiquitin thioesterase OTUB1b", "refseq_ac": [ { "id": "NP_001002500", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002500", "type": "external" } ], "gene_names_uniprotkb": "otub1b; fa19h07; otub1; wu:fa19h07; zgc:92839", "gene_names_refseq": "fa19h07; otub1b; otub1; wu:fa19h07; zgc:92839", "protein_names_uniprotkb": "Ubiquitin thioesterase; 3.4.19.12", "protein_names_refseq": "OTU domain, ubiquitin aldehyde binding 1b; OTU domain, ubiquitin aldehyde binding 1; ubiquitin thioesterase OTUB1b", "tax_id": 7955, "disease": "lupus nephritis (Disease Ontology:DOID:0080162); IgA glomerulonephritis (Disease Ontology:DOID:2986)", "pathway": " (dre:436773); (R-DRE-5689896)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "20040115;23524849;26469318;27189481;28252024", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N0M6", "ec_number_list": [ { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" } ], "go_molecular_function": "GO:0043130 ubiquitin binding;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "", "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F6P1A9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6P2A1-1", "uniprot_id": [ { "id": "F6P2A1_DANRE", "url": "https://www.uniprot.org/uniprot/F6P2A1", "type": "external" } ], "mass": 58504.0, "length": 506, "protein_name": "Vitamin D 25-hydroxylase", "gene_name": "cyp2r1", "organism": "Zebrafish", "refseq_name": "vitamin D 25-hydroxylase", "refseq_ac": [ { "id": "NP_001373291", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373291", "type": "external" } ], "gene_names_uniprotkb": "cyp2r1", "gene_names_refseq": "cyp2r1", "protein_names_uniprotkb": "Vitamin D 25-hydroxylase; 1.14.14.24; Cytochrome P450 2R1", "protein_names_refseq": "vitamin D 25-hydroxylase", "tax_id": 7955, "disease": "vitamin D-dependent rickets type 1B (Disease Ontology:DOID:0080887); pre-eclampsia (Disease Ontology:DOID:10591); hypertension (Disease Ontology:DOID:10763); gestational diabetes (Disease Ontology:DOID:11714); asthma (Disease Ontology:DOID:2841); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); coronary artery disease (Disease Ontology:DOID:3393); brain infarction (Disease Ontology:DOID:3454); coronary stenosis (Disease Ontology:DOID:4248); myocardial infarction (Disease Ontology:DOID:5844); type 1 diabetes mellitus (Disease Ontology:DOID:9744); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:563369); (R-DRE-196791); (R-DRE-211916)", "pathway_count": 3, "publication_count": 10, "publication_id_list": "21087487;21116621;23029160;26365513;26469318;35474468;36864841;38324257;38732518;38885808", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC155662.1, GFIL01007978.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505375, SAMEA3505376 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Aug 21, 2020 this sequence version replaced XP_691824.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; A cytochrome P450 monooxygenase involved in activation of vitamin D precursors. Catalyzes hydroxylation at C-25 of both forms of vitamin D, vitamin D(2) and D(3) (calciol). Can metabolize vitamin D analogs/prodrugs 1alpha-hydroxyvitamin D(2) (doxercalciferol) and 1alpha-hydroxyvitamin D(3) (alfacalcidol) forming 25-hydroxy derivatives. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TDC5", "ec_number_list": [ { "id": "1.14.14.24", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.24", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0030343 vitamin D3 25-hydroxylase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0042359 vitamin D metabolic process;GO:0010906 regulation of glucose metabolic process;GO:0006805 xenobiotic metabolic process;GO:0071425 hematopoietic stem cell proliferation;GO:0071305 cellular response to vitamin D", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F6P2A1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6P346-1", "uniprot_id": [ { "id": "F6P346_DANRE", "url": "https://www.uniprot.org/uniprot/F6P346", "type": "external" } ], "mass": 98395.0, "length": 867, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "wwp2", "organism": "Zebrafish", "refseq_name": "NEDD4-like E3 ubiquitin-protein ligase WWP2 isoform X1", "refseq_ac": [ { "id": "XP_005163228", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005163228", "type": "external" } ], "gene_names_uniprotkb": "wwp2; id:ibd1121; wu:fo87e10; zgc:154036", "gene_names_refseq": "id:ibd1121; wu:fo87e10; wwp2; zgc:154036", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.26", "protein_names_refseq": "NEDD4-like E3 ubiquitin-protein ligase WWP2 isoform X1", "tax_id": 7955, "disease": "", "pathway": " (R-DRE-8948751); (R-DRE-9013406); (R-DRE-9013420)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BAJ0;A0AC58IVJ7", "ec_number_list": [ { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" } ], "go_molecular_function": "GO:0061630 ubiquitin protein ligase activity;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding;GO:0140678 molecular function inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016567 protein ubiquitination;GO:0060021 roof of mouth development;GO:0034765 regulation of monoatomic ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F6P346-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6P3G4-1", "uniprot_id": [ { "id": "PS11A_DANRE", "url": "https://www.uniprot.org/uniprot/F6P3G4", "type": "external" } ], "mass": 47374.0, "length": 421, "protein_name": "26S proteasome non-ATPase regulatory subunit 11A", "gene_name": "psmd11a", "organism": "Zebrafish", "refseq_name": "26S proteasome non-ATPase regulatory subunit 11A", "refseq_ac": [ { "id": "NP_001159710", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001159710", "type": "external" } ], "gene_names_uniprotkb": "psmd11a", "gene_names_refseq": "im:7148232; psmd11a; wu:fb44g10; wu:fc16c05", "protein_names_uniprotkb": "26S proteasome non-ATPase regulatory subunit 11A; 26S proteasome regulatory subunit RPN6-A", "protein_names_refseq": "26S proteasome non-ATPase regulatory subunit 11A; 26S proteasome regulatory subunit RPN6-A; proteasome (prosome, macropain) 216S subunit, non-ATPase, 11a; proteasome (prosome, macropain) 26S subunit, non-ATPase, 11a; proteasome 216S subunit, non-ATPase, 11a", "tax_id": 7955, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888)", "pathway": " (dre:503934)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124767.1, GDQQ01003003.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505373, SAMEA3505374 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1, EH538097.1, EH608175.1 and EH462817.1. On Oct 15, 2009 this sequence version replaced XP_686470.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, psmd11a is required for proteasome assembly (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AUR6", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0022624 proteasome accessory complex;GO:0005634 nucleus;GO:0005829 cytosol;GO:0008541 proteasome regulatory particle, lid subcomplex", "go_biological_process": "GO:0048863 stem cell differentiation;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0043248 proteasome assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F6P3G4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6P697-1", "uniprot_id": [ { "id": "F6P697_DANRE", "url": "https://www.uniprot.org/uniprot/F6P697", "type": "external" } ], "mass": 57989.0, "length": 523, "protein_name": "Heat shock factor protein 1 isoform X1", "gene_name": "hsf1", "organism": "Zebrafish", "refseq_name": "heat shock factor protein 1 isoform X1", "refseq_ac": [ { "id": "XP_009292229", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009292229", "type": "external" } ], "gene_names_uniprotkb": "hsf1; HSF1c; HSF; hsf1a; hsf1b", "gene_names_refseq": "HSF1c; HSF; hsf1a; hsf1b; hsf1", "protein_names_uniprotkb": "Heat shock factor protein 1 isoform X1", "protein_names_refseq": "heat shock factor protein 1 isoform X1", "tax_id": 7955, "disease": "Huntington's disease (Disease Ontology:DOID:12858)", "pathway": " (R-DRE-3371453); (R-DRE-3371511); (R-DRE-3371568); (R-DRE-3371571); (R-DRE-9841251)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3B392", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0009408 response to heat;GO:0002088 lens development in camera-type eye", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F6P697-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6P6X0-1", "uniprot_id": [ { "id": "UBAP1_DANRE", "url": "https://www.uniprot.org/uniprot/F6P6X0", "type": "external" } ], "mass": 49415.0, "length": 453, "protein_name": "Ubiquitin-associated protein 1", "gene_name": "ubap1", "organism": "Zebrafish", "refseq_name": "ubiquitin-associated protein 1", "refseq_ac": [ { "id": "NP_001315273", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315273", "type": "external" } ], "gene_names_uniprotkb": "ubap1", "gene_names_refseq": "UBAP-1; ubap1; zgc:56228", "protein_names_uniprotkb": "Ubiquitin-associated protein 1; UBAP-1", "protein_names_refseq": "ubiquitin-associated protein 1", "tax_id": 7955, "disease": "hereditary spastic paraplegia 80 (Disease Ontology:DOID:0112341)", "pathway": " (dre:393183); (R-DRE-917729)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "23594743;30929741;31203368", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01000802.1, GDQQ01009957.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1 and EH488960.1. On Jun 16, 2016 this sequence version replaced XP_005161070.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7ZV44", "ec_number_list": [], "go_molecular_function": "GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005829 cytosol;GO:0000813 ESCRT I complex", "go_biological_process": "GO:0015031 protein transport;GO:0048675 axon extension;GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F6P6X0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F8W261-1", "uniprot_id": [ { "id": "F8W261_DANRE", "url": "https://www.uniprot.org/uniprot/F8W261", "type": "external" } ], "mass": 57495.0, "length": 514, "protein_name": "N-acetylgalactosamine-6-sulfatase", "gene_name": "galns", "organism": "Zebrafish", "refseq_name": "N-acetylgalactosamine-6-sulfatase precursor", "refseq_ac": [ { "id": "NP_001074110", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074110", "type": "external" } ], "gene_names_uniprotkb": "galns; zgc:158385", "gene_names_refseq": "galns; zgc:158385", "protein_names_uniprotkb": "N-acetylgalactosamine-6-sulfatase; 3.1.6.4; Chondroitinsulfatase; Galactose-6-sulfate sulfatase; N-acetylgalactosamine-6-sulfate sulfatase", "protein_names_refseq": "N-acetylgalactosamine-6-sulfatase precursor; galactosamine (N-acetyl)-6-sulfate sulfatase", "tax_id": 7955, "disease": "mucopolysaccharidosis IVA (Disease Ontology:DOID:0111391); mucopolysaccharidosis IV (Disease Ontology:DOID:12804)", "pathway": " (dre:791159); (R-DRE-2022857); (R-DRE-6798695)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "23072875;27189481;34188220;36532084;38495824", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC154123.1, SRR32588727.3180708.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1, EH505880.1 and EH532060.1. On May 15, 2015 this sequence version replaced NP_001074110.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7UYM1", "ec_number_list": [ { "id": "3.4.21.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.4", "type": "external" }, { "id": "2.4.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.1", "type": "external" }, { "id": "3.1.27.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.27.-", "type": "external" }, { "id": "4.6.1.19", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.19", "type": "external" }, { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "3.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.-", "type": "external" }, { "id": "3.2.1.31", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.31", "type": "external" }, { "id": "5.3.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.4.1", "type": "external" }, { "id": "3.1.6.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.4", "type": "external" }, { "id": "3.5.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.4", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "1.1.1.205", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205", "type": "external" }, { "id": "6.3.4.21", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.21", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "5.3.99.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.3", "type": "external" }, { "id": "1.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.5.5", "type": "external" } ], "go_molecular_function": "GO:0043890 N-acetylgalactosamine-6-sulfatase activity;GO:0046872 metal ion binding;GO:0004065 arylsulfatase activity", "go_cellular_component": "GO:0005764 lysosome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F8W261-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F8W3D4-1", "uniprot_id": [ { "id": "F8W3D4_DANRE", "url": "https://www.uniprot.org/uniprot/F8W3D4", "type": "external" } ], "mass": 99196.0, "length": 864, "protein_name": "ATP-dependent RNA helicase", "gene_name": "ddx10", "organism": "Zebrafish", "refseq_name": "probable ATP-dependent RNA helicase DDX10", "refseq_ac": [ { "id": "XP_001922220", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922220", "type": "external" } ], "gene_names_uniprotkb": "ddx10", "gene_names_refseq": "ddx10", "protein_names_uniprotkb": "ATP-dependent RNA helicase; 3.6.4.13", "protein_names_refseq": "probable ATP-dependent RNA helicase DDX10", "tax_id": 7955, "disease": "", "pathway": " (dre:569118)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; RNA helicase., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QV67", "ec_number_list": [ { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F8W3D4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F8W3K6-1", "uniprot_id": [ { "id": "F8W3K6_DANRE", "url": "https://www.uniprot.org/uniprot/F8W3K6", "type": "external" } ], "mass": 32972.0, "length": 295, "protein_name": "Exosome complex component RRP4", "gene_name": "exosc2", "organism": "Zebrafish", "refseq_name": "exosome complex component RRP4", "refseq_ac": [ { "id": "NP_001017572", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017572", "type": "external" } ], "gene_names_uniprotkb": "exosc2; fa97b01; wu:fa97b01; zgc:110117", "gene_names_refseq": "exosc2; fa97b01; wu:fa97b01; zgc:110117", "protein_names_uniprotkb": "Exosome complex component RRP4; Exosome component 2; Ribosomal RNA-processing protein 4", "protein_names_refseq": "exosome complex component RRP4", "tax_id": 7955, "disease": "short stature, hearing loss, retinitis pigmentosa, and distinctive facies (Disease Ontology:DOID:0081175)", "pathway": " (dre:550234); (R-DRE-429958); (R-DRE-450385); (R-DRE-450513); (R-DRE-450604); (R-DRE-9930044)", "pathway_count": 6, "publication_count": 5, "publication_id_list": "17024299;26469318;27189481;33333712;33600438", "class_list": "", "function": "Exosc2 deficiency leads to developmental disorders by causing a nucleotide pool imbalance in zebrafish. Erratum:[Biochem Biophys Res Commun. 2021 Mar 26;546:200. PMID: 33589142], [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N4Y5", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0000176 nuclear exosome (RNase complex);GO:0000177 cytoplasmic exosome (RNase complex)", "go_biological_process": "GO:0009259 ribonucleotide metabolic process;GO:0003407 neural retina development;GO:0021510 spinal cord development;GO:0000956 nuclear-transcribed mRNA catabolic process;GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F8W3K6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F8W3S7-1", "uniprot_id": [ { "id": "F8W3S7_DANRE", "url": "https://www.uniprot.org/uniprot/F8W3S7", "type": "external" } ], "mass": 34424.0, "length": 318, "protein_name": "Mitochondrial glutamate carrier 1", "gene_name": "slc25a22b", "organism": "Zebrafish", "refseq_name": "mitochondrial glutamate carrier 1", "refseq_ac": [ { "id": "XP_009301224", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301224", "type": "external" } ], "gene_names_uniprotkb": "slc25a22b", "gene_names_refseq": "slc25a22b", "protein_names_uniprotkb": "Mitochondrial glutamate carrier 1; Glutamate/H(+) symporter 1; Solute carrier family 25 member 22", "protein_names_refseq": "mitochondrial glutamate carrier 1", "tax_id": 7955, "disease": "developmental and epileptic encephalopathy 3 (Disease Ontology:DOID:0080440)", "pathway": " (dre:100005520)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mitochondrial glutamate/H(+) symporter. Responsible for the transport of glutamate from the cytosol into the mitochondrial matrix with the concomitant import of a proton. Plays a role in the control of glucose-stimulated insulin secretion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M3ATY8", "ec_number_list": [], "go_molecular_function": "GO:0005313 L-glutamate transmembrane transporter activity;GO:0015183 L-aspartate transmembrane transporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0015810 aspartate transmembrane transport;GO:0015813 L-glutamate transmembrane transport;GO:0043490 malate-aspartate shuttle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F8W3S7-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F8W442-1", "uniprot_id": [ { "id": "F8W442_DANRE", "url": "https://www.uniprot.org/uniprot/F8W442", "type": "external" } ], "mass": 40260.0, "length": 354, "protein_name": "Guanine nucleotide-binding protein G(o) subunit alpha", "gene_name": "gnao1a", "organism": "Zebrafish", "refseq_name": "guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a isoform X1", "refseq_ac": [ { "id": "XP_005159126", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005159126", "type": "external" } ], "gene_names_uniprotkb": "gnao1a; gnao1; wu:fq26h05; zgc:73315", "gene_names_refseq": "gnao1a; gnao1; wu:fq26h05; zgc:73315", "protein_names_uniprotkb": "Guanine nucleotide-binding protein G(o) subunit alpha", "protein_names_refseq": "guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a isoform X1", "tax_id": 7955, "disease": "early infantile epileptic encephalopathy (Disease Ontology:DOID:0050709); developmental and epileptic encephalopathy 17 (Disease Ontology:DOID:0080450); developmental and epileptic encephalopathy (Disease Ontology:DOID:0112202); neurodevelopmental disorder with involuntary movements (Disease Ontology:DOID:0112276); McCune Albright syndrome (Disease Ontology:DOID:1858)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins. Signaling is mediated via effector proteins, such as adenylate cyclase. Inhibits adenylate cyclase activity, leading to decreased intracellular cAMP levels., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B616", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0031821 G protein-coupled serotonin receptor binding;GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0031683 G-protein beta/gamma-subunit complex binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005834 heterotrimeric G-protein complex", "go_biological_process": "GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007212 G protein-coupled dopamine receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F8W442-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F8W494-1", "uniprot_id": [ { "id": "F8W494_DANRE", "url": "https://www.uniprot.org/uniprot/F8W494", "type": "external" } ], "mass": 33774.0, "length": 314, "protein_name": "Mitochondrial glutamate carrier 1", "gene_name": "slc25a22a", "organism": "Zebrafish", "refseq_name": "mitochondrial glutamate carrier 1", "refseq_ac": [ { "id": "XP_001922072", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922072", "type": "external" } ], "gene_names_uniprotkb": "slc25a22a", "gene_names_refseq": "slc25a22a", "protein_names_uniprotkb": "Mitochondrial glutamate carrier 1; Glutamate/H(+) symporter 1; Solute carrier family 25 member 22", "protein_names_refseq": "mitochondrial glutamate carrier 1", "tax_id": 7955, "disease": "developmental and epileptic encephalopathy 3 (Disease Ontology:DOID:0080440)", "pathway": " (dre:571044); (R-DRE-442660); (R-DRE-9856872)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mitochondrial glutamate/H(+) symporter. Responsible for the transport of glutamate from the cytosol into the mitochondrial matrix with the concomitant import of a proton. Plays a role in the control of glucose-stimulated insulin secretion., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QLI9;A0AC58IWX0", "ec_number_list": [], "go_molecular_function": "GO:0005313 L-glutamate transmembrane transporter activity;GO:0015183 L-aspartate transmembrane transporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0015810 aspartate transmembrane transport;GO:0015813 L-glutamate transmembrane transport;GO:0043490 malate-aspartate shuttle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F8W494-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F8W4G4-1", "uniprot_id": [ { "id": "F8W4G4_DANRE", "url": "https://www.uniprot.org/uniprot/F8W4G4", "type": "external" } ], "mass": 35752.0, "length": 319, "protein_name": "Transcription factor Ovo-like 1a", "gene_name": "ovol1a", "organism": "Zebrafish", "refseq_name": "putative transcription factor Ovo-like 1a", "refseq_ac": [ { "id": "NP_001108216", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108216", "type": "external" } ], "gene_names_uniprotkb": "ovol1a; ovol1; sb:cb956; zgc:171804", "gene_names_refseq": "ovol1a; ovol1; sb:cb956; zgc:171804", "protein_names_uniprotkb": "Transcription factor Ovo-like 1a", "protein_names_refseq": "ovo-like 1; ovo-like zinc finger 1; putative transcription factor Ovo-like 1a", "tax_id": 7955, "disease": "", "pathway": " (dre:792456)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "20463035;22931925;26469318;26692521;27189481;27754889", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC155080.1, GDQH01007358.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505378, SAMEA3505385 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On or before Jun 21, 2024 this sequence version replaced XP_021333289.1, NP_001108216.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9Q819", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0009913 epidermal cell differentiation;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription;GO:0001755 neural crest cell migration;GO:0009968 negative regulation of signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F8W4G4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F8W4I7-1", "uniprot_id": [ { "id": "F8W4I7_DANRE", "url": "https://www.uniprot.org/uniprot/F8W4I7", "type": "external" } ], "mass": 41559.0, "length": 373, "protein_name": "carbonic anhydrase", "gene_name": "ca14", "organism": "Zebrafish", "refseq_name": "carbonic anhydrase 14 precursor", "refseq_ac": [ { "id": "NP_001315073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315073", "type": "external" } ], "gene_names_uniprotkb": "ca14; zgc:123188", "gene_names_refseq": "ca14; zgc:123188", "protein_names_uniprotkb": "carbonic anhydrase; 4.2.1.1", "protein_names_refseq": "carbonic anhydrase 14 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:567897); (R-DRE-1475029)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "18322140;18945954;23565095;25843033;26469318;28695384;29230365;31709752;31934309", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588729.16867923.1, SRR32588719.124214.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505381, SAMEA3505388 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Jun 7, 2016 this sequence version replaced XP_009290349.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Hypoxia-inducible carbonic anhydrase IX (CAIX) expression is insufficient to alleviate intracellular metabolic acidosis in the muscle of zebrafish, Danio rerio., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P9L3", "ec_number_list": [ { "id": "4.2.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.1", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004089 carbonate dehydratase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0043010 camera-type eye development;GO:0002088 lens development in camera-type eye", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "F8W4I7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F8W512-1", "uniprot_id": [ { "id": "F8W512_DANRE", "url": "https://www.uniprot.org/uniprot/F8W512", "type": "external" } ], "mass": 27132.0, "length": 236, "protein_name": "Phosducin", "gene_name": "pdca", "organism": "Zebrafish", "refseq_name": "phosducin a", "refseq_ac": [ { "id": "NP_001278429", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001278429", "type": "external" } ], "gene_names_uniprotkb": "pdca; PDC; pdc1; pdcr", "gene_names_refseq": "PDC; pdc1; pdca; pdcr", "protein_names_uniprotkb": "Phosducin", "protein_names_refseq": "PDCb1; phosducin 1; phosducin a", "tax_id": 7955, "disease": "", "pathway": " (dre:386613)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12223214;16379021;19439512;19500364;19504458;26469318;29422031;30886241", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC060908.1, EE208859.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505380, SAMEA3505389 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On Apr 18, 2014 this sequence version replaced XP_682823.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P6P2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0001917 photoreceptor inner segment;GO:0001750 photoreceptor outer segment", "go_biological_process": "GO:0007601 visual perception;GO:0008277 regulation of G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "F8W512-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F8W579-1", "uniprot_id": [ { "id": "F8W579_DANRE", "url": "https://www.uniprot.org/uniprot/F8W579", "type": "external" } ], "mass": 69497.0, "length": 645, "protein_name": "Sodium-dependent phosphate transport protein 2A", "gene_name": "slc34a1a", "organism": "Zebrafish", "refseq_name": "sodium-dependent phosphate transport protein 2A", "refseq_ac": [ { "id": "XP_002664304", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664304", "type": "external" } ], "gene_names_uniprotkb": "slc34a1a", "gene_names_refseq": "slc34a1a", "protein_names_uniprotkb": "Sodium-dependent phosphate transport protein 2A; Na(+)-dependent phosphate cotransporter 2A; Sodium/phosphate cotransporter 2A; Solute carrier family 34 member 1", "protein_names_refseq": "sodium-dependent phosphate transport protein 2A", "tax_id": 7955, "disease": "hereditary hypophosphatemic rickets with hypercalciuria (Disease Ontology:DOID:0050947); infantile hypercalcemia 2 (Disease Ontology:DOID:0061135); hypophosphatemic nephrolithiasis/osteoporosis 1 (Disease Ontology:DOID:0080077); Fanconi renotubular syndrome 2 (Disease Ontology:DOID:0080758); Fanconi syndrome (Disease Ontology:DOID:1062); nephrolithiasis (Disease Ontology:DOID:585); chronic kidney disease (Disease Ontology:DOID:784)", "pathway": " (R-DRE-427589); (R-DRE-5683826)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_002664304.1. COMPLETENESS: full length., [RefSeq]; Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. The cotransport has a Na(+):Pi stoichiometry of 3:1 and is electrogenic., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RDZ0;A0AC58H968", "ec_number_list": [], "go_molecular_function": "GO:0005436 sodium:phosphate symporter activity", "go_cellular_component": "GO:0005903 brush border;GO:0016324 apical plasma membrane;GO:0031982 vesicle", "go_biological_process": "GO:0030643 intracellular phosphate ion homeostasis;GO:0044341 sodium-dependent phosphate transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F8W579-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F8W5L3-1", "uniprot_id": [ { "id": "F8W5L3_DANRE", "url": "https://www.uniprot.org/uniprot/F8W5L3", "type": "external" } ], "mass": 48709.0, "length": 444, "protein_name": "Ornithine aminotransferase", "gene_name": "oat", "organism": "Zebrafish", "refseq_name": "ornithine aminotransferase, mitochondrial", "refseq_ac": [ { "id": "NP_001304099", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001304099", "type": "external" } ], "gene_names_uniprotkb": "oat; si:dkey-68e16.4", "gene_names_refseq": "oat; si:dkey-68e16.4", "protein_names_uniprotkb": "Ornithine aminotransferase; 2.6.1.13", "protein_names_refseq": "ornithine aminotransferase, mitochondrial", "tax_id": 7955, "disease": "gyrate atrophy (Disease Ontology:DOID:1415)", "pathway": " (R-DRE-8964539)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "26469318;28252024;30199544;35772676", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01007558.1, SRR26395017.748225.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000012.1. On or before Jun 26, 2025 this sequence version replaced XP_073773976.1, XP_701334.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Catalyzes the reversible interconversion of L-ornithine and 2-oxoglutarate to L-glutamate semialdehyde and L-glutamate., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P886;A0AC58GW67", "ec_number_list": [ { "id": "2.6.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.13", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0042802 identical protein binding;GO:0008483 transaminase activity;GO:0004587 ornithine aminotransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0055129 L-proline biosynthetic process;GO:0010121 L-arginine catabolic process to proline via ornithine;GO:0019544 L-arginine catabolic process to L-glutamate", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F8W5L3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F8W5R6-1", "uniprot_id": [ { "id": "F8W5R6_DANRE", "url": "https://www.uniprot.org/uniprot/F8W5R6", "type": "external" } ], "mass": 137854.0, "length": 1206, "protein_name": "DNA polymerase subunit gamma-1", "gene_name": "polg", "organism": "Zebrafish", "refseq_name": "DNA polymerase subunit gamma-1 isoform X1", "refseq_ac": [ { "id": "XP_001921130", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001921130", "type": "external" } ], "gene_names_uniprotkb": "polg", "gene_names_refseq": "polg", "protein_names_uniprotkb": "DNA polymerase subunit gamma-1; 2.7.7.7; Mitochondrial DNA polymerase catalytic subunit", "protein_names_refseq": "DNA polymerase subunit gamma-1 isoform X1", "tax_id": 7955, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); cerebellar ataxia (Disease Ontology:DOID:0050753); myelodysplastic syndrome (Disease Ontology:DOID:0050908); Alpers-Huttenlocher syndrome (Disease Ontology:DOID:0080122); mitochondrial DNA depletion syndrome 4b (Disease Ontology:DOID:0080123); sensory ataxic neuropathy, dysarthria, and ophthalmoparesis (Disease Ontology:DOID:0111276); autosomal dominant progressive external ophthalmoplegia 1 (Disease Ontology:DOID:0111521); autosomal recessive progressive external ophthalmoplegia 1 (Disease Ontology:DOID:0111522); premature menopause (Disease Ontology:DOID:10787); chronic progressive external ophthalmoplegia (Disease Ontology:DOID:12558); Parkinson's disease (Disease Ontology:DOID:14330); epilepsy (Disease Ontology:DOID:1826); multiple sclerosis (Disease Ontology:DOID:2377); bipolar disorder (Disease Ontology:DOID:3312); mood disorder (Disease Ontology:DOID:3324); primary ovarian insufficiency (Disease Ontology:DOID:5426); hepatocellular carcinoma (Disease Ontology:DOID:684); mitochondrial metabolism disease (Disease Ontology:DOID:700); mitochondrial encephalomyopathy (Disease Ontology:DOID:890)", "pathway": " (dre:100150924); (R-DRE-9913635)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001921130.2. COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 19, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1QHI8", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" } ], "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0003677 DNA binding;GO:0008408 3'-5' exonuclease activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0042645 mitochondrial nucleoid;GO:0005760 gamma DNA polymerase complex", "go_biological_process": "GO:0006264 mitochondrial DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F8W5R6-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F8W5U2-1", "uniprot_id": [ { "id": "F8W5U2_DANRE", "url": "https://www.uniprot.org/uniprot/F8W5U2", "type": "external" } ], "mass": 70117.0, "length": 615, "protein_name": "Tyrosyl-DNA phosphodiesterase 1", "gene_name": "tdp1", "organism": "Zebrafish", "refseq_name": "tyrosyl-DNA phosphodiesterase 1", "refseq_ac": [ { "id": "XP_700174", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_700174", "type": "external" } ], "gene_names_uniprotkb": "tdp1", "gene_names_refseq": "tdp1", "protein_names_uniprotkb": "Tyrosyl-DNA phosphodiesterase 1", "protein_names_refseq": "tyrosyl-DNA phosphodiesterase 1", "tax_id": 7955, "disease": "spinocerebellar ataxia with axonal neuropathy 1 (Disease Ontology:DOID:0090115)", "pathway": " (dre:571485); (R-DRE-5693571)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_700174.1. COMPLETENESS: full length., [RefSeq]; DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. Has low 3'exonuclease activity and can remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups. Has no exonuclease activity towards DNA or RNA with a 3'phosphate., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7TC11", "ec_number_list": [], "go_molecular_function": "GO:0003690 double-stranded DNA binding;GO:0004527 exonuclease activity;GO:0003697 single-stranded DNA binding;GO:0017005 3'-tyrosyl-DNA phosphodiesterase activity;GO:0090580 phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006281 DNA repair;GO:0008344 adult locomotory behavior;GO:0000012 single strand break repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F8W5U2-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F8WK50-1", "uniprot_id": [ { "id": "FLII_DANRE", "url": "https://www.uniprot.org/uniprot/F8WK50", "type": "external" } ], "mass": 143753.0, "length": 1259, "protein_name": "Protein flightless-1 homolog", "gene_name": "flii", "organism": "Zebrafish", "refseq_name": "protein flightless-1 homolog", "refseq_ac": [ { "id": "NP_001244075", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244075", "type": "external" } ], "gene_names_uniprotkb": "flii", "gene_names_refseq": "flii; im:7141769", "protein_names_uniprotkb": "Protein flightless-1 homolog; Flii actin remodeling protein", "protein_names_refseq": "flightless I actin binding protein; flightless I homolog; protein flightless-1 homolog", "tax_id": 7955, "disease": "dilated cardiomyopathy (Disease Ontology:DOID:12930); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:560281)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "21554867;23594743;37561591;40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AB355792.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB355792.1. On Mar 16, 2012 this sequence version replaced XP_688770.1., [RefSeq]; Embryos defective in flightless I homolog (flii), which encodes for an actin-regulating protein, exhibit normal coilings at 24 hours post fertilization (hpf) that is followed by significantly slower burst swimming at 48 hpf., [RefSeq, PubMed]; Is a regulator of actin polymerization, required for proper myofibril organization and the assembly of cardiomyocyte cell adhesion complexes (PubMed:37561591). Is a regulator of the length of sarcomeric thin filaments (By similarity). Regulates cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation (By similarity). May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005925 focal adhesion;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0051016 barbed-end actin filament capping;GO:0008154 actin polymerization or depolymerization;GO:0045214 sarcomere organization;GO:0051014 actin filament severing", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F8WK50-1", "record_type": "protein", "filter_code": "0000000.0100111.010000.000000000000000001.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "I3IRW7-1", "uniprot_id": [ { "id": "I3IRW7_DANRE", "url": "https://www.uniprot.org/uniprot/I3IRW7", "type": "external" } ], "mass": 55730.0, "length": 500, "protein_name": "4-aminobutyrate aminotransferase, mitochondrial", "gene_name": "abat", "organism": "Zebrafish", "refseq_name": "4-aminobutyrate aminotransferase, mitochondrial", "refseq_ac": [ { "id": "NP_958906", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_958906", "type": "external" } ], "gene_names_uniprotkb": "abat; cb880; fj82a01; wu:fj82a01", "gene_names_refseq": "abat; cb880; fj82a01; wu:fj82a01", "protein_names_uniprotkb": "4-aminobutyrate aminotransferase, mitochondrial; (S)-3-amino-2-methylpropionate transaminase; 2.6.1.19; 2.6.1.22; GABA aminotransferase; Gamma-amino-N-butyrate transaminase; L-AIBAT", "protein_names_refseq": "4-aminobutyrate aminotransferase, mitochondrial; GABA-T", "tax_id": 7955, "disease": "West syndrome (Disease Ontology:DOID:0050562); GABA aminotransferase deficiency (Disease Ontology:DOID:0060174); Parkinsonism (Disease Ontology:DOID:0080855); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); Huntington's disease (Disease Ontology:DOID:12858); depressive disorder (Disease Ontology:DOID:1596); status epilepticus (Disease Ontology:DOID:1824); epilepsy (Disease Ontology:DOID:1826); reflex epilepsy (Disease Ontology:DOID:2548); ischemia (Disease Ontology:DOID:326); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (dre:378968); (R-DRE-916853)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "17362888;21947502;24714733;25662174;26469318;33092822;33260372;33296199;33800130;35318061", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC045433.1, GDQH01001444.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1 and EH544013.1. On Aug 5, 2010 this sequence version replaced NP_958906.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7V0P5;A0AC58IH31;A0AC58IH34;A0AC58IH68", "ec_number_list": [ { "id": "2.6.1.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.19", "type": "external" }, { "id": "2.6.1.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.22", "type": "external" } ], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0008483 transaminase activity;GO:0034386 4-aminobutyrate:2-oxoglutarate transaminase activity;GO:0047298 (S)-3-amino-2-methylpropionate transaminase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0009450 gamma-aminobutyric acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "I3IRW7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "I3IRY7-1", "uniprot_id": [ { "id": "I3IRY7_DANRE", "url": "https://www.uniprot.org/uniprot/I3IRY7", "type": "external" } ], "mass": 44143.0, "length": 390, "protein_name": "Coagulation factor II (Thrombin) receptor-like 1, tandem duplicate 2 isoform X1", "gene_name": "f2rl1.2", "organism": "Zebrafish", "refseq_name": "coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2 isoform X1", "refseq_ac": [ { "id": "XP_005161546", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161546", "type": "external" } ], "gene_names_uniprotkb": "f2rl1.2; PAR2b; par2-21a; zgc:165523", "gene_names_refseq": "PAR2b; f2rl1.2; par2-21a; zgc:165523", "protein_names_uniprotkb": "Coagulation factor II (Thrombin) receptor-like 1, tandem duplicate 2 isoform X1", "protein_names_refseq": "coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2 isoform X1", "tax_id": 7955, "disease": "respiratory allergy (Disease Ontology:DOID:0060496); asthma (Disease Ontology:DOID:2841); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B8I8", "ec_number_list": [], "go_molecular_function": "GO:0015057 thrombin-activated receptor activity;GO:0004930 G protein-coupled receptor activity;GO:0001648 proteinase-activated receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0008283 cell population proliferation;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0007596 blood coagulation;GO:0035025 positive regulation of Rho protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "I3IRY7-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "I3ITM8-1", "uniprot_id": [ { "id": "I3ITM8_DANRE", "url": "https://www.uniprot.org/uniprot/I3ITM8", "type": "external" } ], "mass": 55186.0, "length": 501, "protein_name": "Wiskott-Aldrich syndrome protein family member", "gene_name": "si:ch73-362m14.4", "organism": "Zebrafish", "refseq_name": "actin-binding protein WASF3", "refseq_ac": [ { "id": "XP_003200954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200954", "type": "external" } ], "gene_names_uniprotkb": "si:ch73-362m14.4", "gene_names_refseq": "si:ch73-362m14.4", "protein_names_uniprotkb": "Wiskott-Aldrich syndrome protein family member; WASP family protein member", "protein_names_refseq": "actin-binding protein WASF3", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RTE9;A0AC58IBN7", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0034237 protein kinase A regulatory subunit binding;GO:0071933 Arp2/3 complex binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0030027 lamellipodium;GO:0031209 SCAR complex", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "I3ITM8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "I6V1W0-1", "uniprot_id": [ { "id": "BMBL_DANRE", "url": "https://www.uniprot.org/uniprot/I6V1W0", "type": "external" } ], "mass": 68061.0, "length": 612, "protein_name": "Protein brambleberry", "gene_name": "bmb", "organism": "Zebrafish", "refseq_name": "protein brambleberry precursor", "refseq_ac": [ { "id": "NP_001257483", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257483", "type": "external" } ], "gene_names_uniprotkb": "bmb", "gene_names_refseq": "bmb; fi04f09; wu:fi04f09", "protein_names_uniprotkb": "Protein brambleberry", "protein_names_refseq": "protein brambleberry precursor; protein brambleberry", "tax_id": 7955, "disease": "", "pathway": " (dre:559540)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22863006", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: JX073281.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476755, SAMEA4476776 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JX073281.1. On Jul 18, 2012 this sequence version replaced XP_687980.1., [RefSeq]; Required for nuclear membrane fusion during karyogamy., [UniProtKB, PubMed]; Study identified brambleberry, a maternal-effect zebrafish mutant that disrupts karyomere fusion, resulting in formation of multiple micronuclei. As karyomeres form, Brambleberry protein localizes to the nuclear envelope, with prominent puncta evident near karyomere-karyomere interfaces corresponding to membrane fusion sites., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0031965 nuclear membrane", "go_biological_process": "GO:0007344 pronuclear fusion;GO:0061472 karyomere membrane fusion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I6V1W0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M9MM98-1", "uniprot_id": [ { "id": "M9MM98_DANRE", "url": "https://www.uniprot.org/uniprot/M9MM98", "type": "external" } ], "mass": 110885.0, "length": 997, "protein_name": "DNA-binding protein SMUBP-2", "gene_name": "ighmbp2", "organism": "Zebrafish", "refseq_name": "DNA-binding protein SMUBP-2", "refseq_ac": [ { "id": "NP_001038365", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038365", "type": "external" } ], "gene_names_uniprotkb": "ighmbp2; ighmbp2l; si:ch211-238n5.2; zgc:110400", "gene_names_refseq": "ighmbp2l; ighmbp2; si:ch211-238n5.2; zgc:110400", "protein_names_uniprotkb": "DNA-binding protein SMUBP-2; 3.6.4.12; 3.6.4.13; ATP-dependent helicase IGHMBP2", "protein_names_refseq": "DNA-binding protein SMUBP-2; immunoglobulin mu binding protein 2, like", "tax_id": 7955, "disease": "Charcot-Marie-Tooth disease axonal type 2S (Disease Ontology:DOID:0110171); autosomal recessive distal hereditary motor neuronopathy 1 (Disease Ontology:DOID:0111064)", "pathway": " (dre:556484)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12618376;21873635", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01013195.1, BC171648.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000018.1. On Jan 10, 2007 this sequence version replaced XP_688104.1., [RefSeq]; 5' to 3' helicase that unwinds RNA and DNA duplexes in an ATP-dependent reaction. Specific to 5'-phosphorylated single-stranded guanine-rich sequences. May play a role in RNA metabolism, ribosome biogenesis or initiation of translation. May play a role in regulation of transcription. Interacts with tRNA-Tyr., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N9K7", "ec_number_list": [ { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016787 hydrolase activity;GO:0000049 tRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0030424 axon;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006974 DNA damage response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "M9MM98-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "N0GW19-1", "uniprot_id": [ { "id": "N0GW19_DANRE", "url": "https://www.uniprot.org/uniprot/N0GW19", "type": "external" } ], "mass": 12670.0, "length": 118, "protein_name": "Interleukin-8b.1 precursor", "gene_name": "cxcl8b.1", "organism": "Zebrafish", "refseq_name": "interleukin-8b.1 precursor", "refseq_ac": [ { "id": "NP_001314914", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314914", "type": "external" } ], "gene_names_uniprotkb": "cxcl8b.1; il8l1", "gene_names_refseq": "cxcl8b.1; il8l1", "protein_names_uniprotkb": "Interleukin-8b.1 precursor", "protein_names_refseq": "CXCL8bb; cxcl8_l2_chr17; il8l2; interleukin-8, like 1; interleukin-8b.1 precursor", "tax_id": 7955, "disease": "autoimmune uveitis (Disease Ontology:DOID:0040088); chikungunya (Disease Ontology:DOID:0050012); extrapulmonary tuberculosis (Disease Ontology:DOID:0050598); COVID-19 (Disease Ontology:DOID:0080600); urinary tract infection (Disease Ontology:DOID:0080784); acute asthma (Disease Ontology:DOID:0080810); trypanosomiasis (Disease Ontology:DOID:10113); leprosy (Disease Ontology:DOID:1024); common cold (Disease Ontology:DOID:10459); brucellosis (Disease Ontology:DOID:11077); trachoma (Disease Ontology:DOID:11265); adult respiratory distress syndrome (Disease Ontology:DOID:11394); primary biliary cholangitis (Disease Ontology:DOID:12236); respiratory syncytial virus infectious disease (Disease Ontology:DOID:1273); eumycotic mycetoma (Disease Ontology:DOID:13078); biliary atresia (Disease Ontology:DOID:13608); cystic fibrosis (Disease Ontology:DOID:1485); intrahepatic cholestasis (Disease Ontology:DOID:1852); hepatitis C (Disease Ontology:DOID:1883); vulvovaginal candidiasis (Disease Ontology:DOID:2272); multiple sclerosis (Disease Ontology:DOID:2377); Mycobacterium avium complex disease (Disease Ontology:DOID:2755); endometriosis (Disease Ontology:DOID:289); severe acute respiratory syndrome (Disease Ontology:DOID:2945); pulmonary tuberculosis (Disease Ontology:DOID:2957); HTLV-1-associated myelopathy/tropical spastic paraparesis (Disease Ontology:DOID:321); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); pulmonary fibrosis (Disease Ontology:DOID:3770); tuberculosis (Disease Ontology:DOID:399); gastritis (Disease Ontology:DOID:4029); bacterial gastritis (Disease Ontology:DOID:4033); liver cirrhosis (Disease Ontology:DOID:5082); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); stomach carcinoma (Disease Ontology:DOID:5517); acute pyelonephritis (Disease Ontology:DOID:559); viral encephalitis (Disease Ontology:DOID:646); hepatocellular carcinoma (Disease Ontology:DOID:684); visceral leishmaniasis (Disease Ontology:DOID:9146)", "pathway": " (dre:100536594); (R-DRE-380108); (R-DRE-418594)", "pathway_count": 3, "publication_count": 10, "publication_id_list": "20865040;22705555;22949679;23145839;23509368;38275965;38431640;38643762;38891786;39273457", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH441857.1, EH536693.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505372, SAMEA3505378 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH441857.1 and EH536693.1. On Jun 1, 2016 this sequence version replaced XP_003198940.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Ligand for cxcr3.2. Chemotactic for macrophages., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 38, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P3D2", "ec_number_list": [], "go_molecular_function": "GO:0042056 chemoattractant activity;GO:0008009 chemokine activity;GO:0045236 CXCR chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006954 inflammatory response;GO:0006955 immune response;GO:0070098 chemokine-mediated signaling pathway;GO:0002523 leukocyte migration involved in inflammatory response;GO:0009617 response to bacterium", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "N0GW19-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O42356-1", "uniprot_id": [ { "id": "RX1_DANRE", "url": "https://www.uniprot.org/uniprot/O42356", "type": "external" } ], "mass": 36936.0, "length": 330, "protein_name": "Retinal homeobox protein Rx1", "gene_name": "rx1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "rx1", "gene_names_refseq": "", "protein_names_uniprotkb": "Retinal homeobox protein Rx1", "protein_names_refseq": "", "tax_id": 7955, "disease": "syndromic microphthalmia 16 (Disease Ontology:DOID:0060842); retinitis pigmentosa 95 (Disease Ontology:DOID:0061112); age related macular degeneration 6 (Disease Ontology:DOID:0110018); cone-rod dystrophy 11 (Disease Ontology:DOID:0111018)", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "11180949;9177348", "class_list": "", "function": "Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0003407 neural retina development;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0010842 retina layer formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "O42356-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O42365-1", "uniprot_id": [ { "id": "HXA2B_DANRE", "url": "https://www.uniprot.org/uniprot/O42365", "type": "external" } ], "mass": 39814.0, "length": 363, "protein_name": "Homeobox protein Hox-A2b", "gene_name": "hoxa2b", "organism": "Zebrafish", "refseq_name": "homeobox protein Hox-A2b", "refseq_ac": [ { "id": "NP_571181", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571181", "type": "external" } ], "gene_names_uniprotkb": "hoxa2b; Z-75; hoxa2", "gene_names_refseq": "Z-75; hoxa2b; hoxa2", "protein_names_uniprotkb": "Homeobox protein Hox-A2b; Hox-A2", "protein_names_refseq": "etID309949.16; homeo box A2b; homeobox gene A-2; homeobox protein Hox-A2b; hox-A2", "tax_id": 7955, "disease": "", "pathway": " (dre:30325)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11076758;16174031;23594743;9425135", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AF307010.1, BC162328.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF307010.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q4PRA7;Q9DEZ0", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "O42365-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "O42367-1", "uniprot_id": [ { "id": "HXB2A_DANRE", "url": "https://www.uniprot.org/uniprot/O42367", "type": "external" } ], "mass": 42149.0, "length": 390, "protein_name": "Homeobox protein Hox-B2a", "gene_name": "hoxb2a", "organism": "Zebrafish", "refseq_name": "homeobox protein Hox-B2a", "refseq_ac": [ { "id": "NP_571191", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571191", "type": "external" } ], "gene_names_uniprotkb": "hoxb2a; hoxb2", "gene_names_refseq": "Z-151; hm:zehn0229; hoxb2a; hoxb2; zehn0229", "protein_names_uniprotkb": "Homeobox protein Hox-B2a; Hox-B2", "protein_names_refseq": "homeo box B2a; homeobox gene B-2; homeobox protein Hox-B2a; hox-B2", "tax_id": 7955, "disease": "", "pathway": " (dre:30338)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "23594743;9425135;9853959", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC065967.1, AF071568.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC065967.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Plays an important role in the patterning of hindbrain and pharyngeal arches., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O93365", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "O42367-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P09074-1", "uniprot_id": [ { "id": "HXC5A_DANRE", "url": "https://www.uniprot.org/uniprot/P09074", "type": "external" } ], "mass": 26909.0, "length": 232, "protein_name": "Homeobox protein Hox-C5a", "gene_name": "hoxc5a", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "hoxc5a; ZF-25; hox-3.4; hoxc5; z-142; zf25", "gene_names_refseq": "", "protein_names_uniprotkb": "Homeobox protein Hox-C5a; Homeobox protein Hox-3.4; Homeobox protein Zf-25; Hox-C5", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 4, "publication_id_list": "16174031;2892487;8104460;9425136", "class_list": "", "function": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O57368;Q4PR90", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0001708 cell fate specification;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007420 brain development;GO:0009952 anterior/posterior pattern specification", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P09074-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0C7U4-1", "uniprot_id": [ { "id": "C3AR_DANRE", "url": "https://www.uniprot.org/uniprot/P0C7U4", "type": "external" } ], "mass": 41050.0, "length": 361, "protein_name": "C3a anaphylatoxin chemotactic receptor", "gene_name": "c3ar1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "c3ar1", "gene_names_refseq": "", "protein_names_uniprotkb": "C3a anaphylatoxin chemotactic receptor; C3AR; C3a-R", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a, stimulating chemotaxis, granule enzyme release and superoxide anion production. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. C3AR1 is coupled to G(i)/G(o) (GNAI1 or GNAO1) G alpha proteins and mediates inhibition of adenylate cyclase., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004878 complement component C5a receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0002430 complement receptor mediated signaling pathway;GO:0006935 chemotaxis;GO:0006954 inflammatory response;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P0C7U4-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0C8M3-1", "uniprot_id": [ { "id": "SVBP_DANRE", "url": "https://www.uniprot.org/uniprot/P0C8M3", "type": "external" } ], "mass": 7762.0, "length": 65, "protein_name": "Small vasohibin-binding protein", "gene_name": "svbp", "organism": "Zebrafish", "refseq_name": "small vasohibin-binding protein", "refseq_ac": [ { "id": "NP_001189361", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189361", "type": "external" } ], "gene_names_uniprotkb": "svbp; ccdc23", "gene_names_refseq": "ccdc23; svbp", "protein_names_uniprotkb": "Small vasohibin-binding protein; Coiled-coil domain-containing protein 23", "protein_names_refseq": "coiled-coil domain containing 23; coiled-coil domain-containing protein 23; small vasohibin-binding protein; zmp:0000001231", "tax_id": 7955, "disease": "", "pathway": " (dre:798425)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH595729.1, CK697038.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1 and EH452696.1. On Jan 30, 2011 this sequence version replaced XP_001334435.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Enhances the tyrosine carboxypeptidase activity of vash1 and vash2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin. Also required to enhance the solubility and secretion of vash1 and vash2. May play a role in axon and excitatory synapse formation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0045177 apical part of cell", "go_biological_process": "GO:0006508 proteolysis;GO:0009306 protein secretion;GO:0031397 negative regulation of protein ubiquitination;GO:0061564 axon development;GO:1905048 regulation of metallopeptidase activity", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P0C8M3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0C8Y1-1", "uniprot_id": [ { "id": "MZT1_DANRE", "url": "https://www.uniprot.org/uniprot/P0C8Y1", "type": "external" } ], "mass": 8054.0, "length": 75, "protein_name": "Mitotic-spindle organizing protein 1", "gene_name": "mzt1", "organism": "Zebrafish", "refseq_name": "mitotic-spindle organizing protein 1", "refseq_ac": [ { "id": "NP_001289735", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289735", "type": "external" } ], "gene_names_uniprotkb": "mzt1; mozart1", "gene_names_refseq": "mzt1; si:ch211-141i4.2; si:dkey-15d12.2", "protein_names_uniprotkb": "Mitotic-spindle organizing protein 1; Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1", "protein_names_refseq": "mitotic-spindle organizing protein 1; mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1", "tax_id": 7955, "disease": "", "pathway": " (dre:100333194); (R-DRE-380320)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC059646.1, BI672111.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476797 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1, EH547451.1, EH550964.1 and EH611695.1. On Nov 15, 2014 this sequence version replaced XP_002660476.1., [RefSeq]; Required for gamma-tubulin complex recruitment to the centrosome., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005813 centrosome;GO:0005819 spindle;GO:0031021 interphase microtubule organizing center;GO:0000931 gamma-tubulin ring complex", "go_biological_process": "GO:0090307 mitotic spindle assembly;GO:0033566 gamma-tubulin complex localization;GO:0051415 microtubule nucleation by interphase microtubule organizing center", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "P0C8Y1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0CK98-1", "uniprot_id": [ { "id": "CCD39_DANRE", "url": "https://www.uniprot.org/uniprot/P0CK98", "type": "external" } ], "mass": 108989.0, "length": 947, "protein_name": "Coiled-coil domain-containing protein 39", "gene_name": "ccdc39", "organism": "Zebrafish", "refseq_name": "coiled-coil domain-containing protein 39", "refseq_ac": [ { "id": "NP_001410743", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410743", "type": "external" } ], "gene_names_uniprotkb": "ccdc39", "gene_names_refseq": "ccdc39", "protein_names_uniprotkb": "Coiled-coil domain-containing protein 39", "protein_names_refseq": "coiled-coil domain containing 39; coiled-coil domain-containing protein 39", "tax_id": 7955, "disease": "Kartagener syndrome (Disease Ontology:DOID:0050144); visceral heterotaxy (Disease Ontology:DOID:0050545); primary ciliary dyskinesia 14 (Disease Ontology:DOID:0110598); hydrocephalus (Disease Ontology:DOID:10908)", "pathway": " (dre:100005620)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "21131972;23594743;25139857;27477027;29475374;33728688;34397384", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01010611.1, SRR32588714.2439734.1 [ECO:0000332] RNAseq introns :: partial sample support SAMEA3505370, SAMEA3505371 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On or before Aug 8, 2025 this sequence version replaced XP_073765864.1, NP_001410743.1., [RefSeq]; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with ccdc40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "E7F0V3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005930 axoneme", "go_biological_process": "GO:0007368 determination of left/right symmetry;GO:0036159 inner dynein arm assembly;GO:0060285 cilium-dependent cell motility;GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry;GO:0070286 axonemal dynein complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P0CK98-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0DM44-1", "uniprot_id": [ { "id": "LGR6_DANRE", "url": "https://www.uniprot.org/uniprot/P0DM44", "type": "external" } ], "mass": 105933.0, "length": 962, "protein_name": "Leucine-rich repeat-containing G protein-coupled receptor 6", "gene_name": "lgr6", "organism": "Zebrafish", "refseq_name": "leucine-rich repeat-containing G-protein coupled receptor 6 precursor", "refseq_ac": [ { "id": "NP_001410768", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410768", "type": "external" } ], "gene_names_uniprotkb": "lgr6; si:dkeyp-116f3.1", "gene_names_refseq": "lgr6; si:dkeyp-116f3.1", "protein_names_uniprotkb": "Leucine-rich repeat-containing G protein-coupled receptor 6", "protein_names_refseq": "leucine-rich repeat-containing G-protein coupled receptor 6 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:100330212)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21570488;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01024519.1, GDQQ01041820.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JBMGRA010000023.1. On Aug 16, 2023 this sequence version replaced XP_017209265.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Lgr6 is expressed in the notochord, Kupffer's vesicle, the most anterior region of diencephalon, otic vesicles, and the anterior and posterior lateral line primordia by 24h post-fertilization (hpf)., [RefSeq, PubMed]; Receptor for R-spondins that potentiates the canonical Wnt signaling pathway. Upon binding to R-spondins (rspo1, rspo2, rspo3 or rspo4), associates with phosphorylated lrp6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G protein-coupled receptors, does not activate heterotrimeric G proteins to transduce the signal (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016500 protein-hormone receptor activity;GO:0008528 G protein-coupled peptide receptor activity;GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0009755 hormone-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P0DM44-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P0DOC8-1", "uniprot_id": [ { "id": "CF418_DANRE", "url": "https://www.uniprot.org/uniprot/P0DOC8", "type": "external" } ], "mass": 23085.0, "length": 202, "protein_name": "Cilia- and flagella-associated protein 418", "gene_name": "cfap418", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "cfap418; c16h8orf37; dkey-242e21.4; si:dkey-242e21.4", "gene_names_refseq": "", "protein_names_uniprotkb": "Cilia- and flagella-associated protein 418", "protein_names_refseq": "", "tax_id": 7955, "disease": "Bardet-Biedl syndrome 21 (Disease Ontology:DOID:0081010); cone-rod dystrophy 16 (Disease Ontology:DOID:0111022); retinitis pigmentosa (Disease Ontology:DOID:10584)", "pathway": " (dre:100534958)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "27008867;35863537", "class_list": "", "function": "May be involved in photoreceptor outer segment disk morphogenesis (By similarity)., [UniProtKB, UniProtKB]; May be involved in photoreceptor outer segment disk morphogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0001917 photoreceptor inner segment;GO:0097546 ciliary base", "go_biological_process": "GO:0070121 Kupffer's vesicle development;GO:0032402 melanosome transport;GO:0008594 photoreceptor cell morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P0DOC8-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P13104-1", "uniprot_id": [ { "id": "TPM1_DANRE", "url": "https://www.uniprot.org/uniprot/P13104", "type": "external" } ], "mass": 32723.0, "length": 284, "protein_name": "Tropomyosin alpha-1 chain", "gene_name": "tpma", "organism": "Zebrafish", "refseq_name": "tropomyosin alpha-1 chain", "refseq_ac": [ { "id": "NP_571180", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571180", "type": "external" } ], "gene_names_uniprotkb": "tpma; tpm1", "gene_names_refseq": "TPM1; fb37a09; tm; tpma; wu:fb37a09", "protein_names_uniprotkb": "Tropomyosin alpha-1 chain; Alpha-tropomyosin; Tropomyosin-1", "protein_names_refseq": "TPM1-2 alpha; tropomyosin 1-2 nu; tropomyosin alpha-1 chain", "tax_id": 7955, "disease": "familial hypertrophic cardiomyopathy (Disease Ontology:DOID:0080326); hypertrophic cardiomyopathy 3 (Disease Ontology:DOID:0110309); dilated cardiomyopathy 1Y (Disease Ontology:DOID:0110457); dilated cardiomyopathy (Disease Ontology:DOID:12930)", "pathway": " (dre:30324)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11002340;2788276", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC062870.1, AF180892.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC062870.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005884 actin filament;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0007015 actin filament organization;GO:0060048 cardiac muscle contraction;GO:0061515 myeloid cell development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P13104-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P15861-1", "uniprot_id": [ { "id": "HXB6A_DANRE", "url": "https://www.uniprot.org/uniprot/P15861", "type": "external" } ], "mass": 26088.0, "length": 228, "protein_name": "Homeobox protein Hox-B6a", "gene_name": "hoxb6a", "organism": "Zebrafish", "refseq_name": "homeobox protein Hox-B6a", "refseq_ac": [ { "id": "NP_571194", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571194", "type": "external" } ], "gene_names_uniprotkb": "hoxb6a; hox-b6; hoxb6; zf22", "gene_names_refseq": "ZF-22; ZF22; hox-2.2; hox-B6; hoxb6a; hoxb6; z-39", "protein_names_uniprotkb": "Homeobox protein Hox-B6a; Homeobox protein Zf-22; Hox-B6", "protein_names_refseq": "homeo box B6a; homeobox gene B-6; homeobox protein Hox-B6a; homeobox protein Zf-22", "tax_id": 7955, "disease": "", "pathway": " (dre:30341)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "16174031;1968004;23594743;8097929;9425136", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC162839.1, EE306430.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X17267.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4PRA2;Q8AWY8", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0009952 anterior/posterior pattern specification", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P15861-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P15862-1", "uniprot_id": [ { "id": "HXC6A_DANRE", "url": "https://www.uniprot.org/uniprot/P15862", "type": "external" } ], "mass": 26733.0, "length": 231, "protein_name": "Homeobox protein Hox-C6a", "gene_name": "hoxc6a", "organism": "Zebrafish", "refseq_name": "homeobox protein Hox-C6a", "refseq_ac": [ { "id": "NP_571198", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571198", "type": "external" } ], "gene_names_uniprotkb": "hoxc6a; hox-c6; hoxc6; zf61; zgc:101882", "gene_names_refseq": "HOX-C6; ZF-61; hoxc-6; hoxc6a; hoxc6; zgc:101882", "protein_names_uniprotkb": "Homeobox protein Hox-C6a; Homeobox protein Zf-61; Hox-C6", "protein_names_refseq": "etID228114.23; homeo box C6a; homeobox gene C-6; homeobox protein Hox-C6a; homeobox protein Zf-61", "tax_id": 7955, "disease": "", "pathway": " (dre:30346)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15385162;16174031;1968004;9425136;9831563", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH580294.1, BC083307.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF071265.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4PR89;Q5XJJ4;Q6LAJ7;Q9PWM4", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0009952 anterior/posterior pattern specification", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P15862-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P17561-1", "uniprot_id": [ { "id": "EPD_DANRE", "url": "https://www.uniprot.org/uniprot/P17561", "type": "external" } ], "mass": 24472.0, "length": 217, "protein_name": "Ependymin", "gene_name": "epd", "organism": "Zebrafish", "refseq_name": "ependymin precursor", "refseq_ac": [ { "id": "NP_571080", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571080", "type": "external" } ], "gene_names_uniprotkb": "epd", "gene_names_refseq": "epd; epn; fj34b05; wu:fj34b05; zgc:109854", "protein_names_uniprotkb": "Ependymin; EPD", "protein_names_refseq": "ependymin precursor; etID309817.5", "tax_id": 7955, "disease": "", "pathway": " (dre:30199)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "1524676;21483679;2243597", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC092712.1, EH454620.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC092712.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Ependymin in control of aggressive behaviour Publication Status: Online-Only, [RefSeq, PubMed]; May play a role in neural plasticity. May be involved during axon regeneration., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q561Y9", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005764 lysosome", "go_biological_process": "GO:0007160 cell-matrix adhesion", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P17561-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P51046-1", "uniprot_id": [ { "id": "MR1AA_DANRE", "url": "https://www.uniprot.org/uniprot/P51046", "type": "external" } ], "mass": 39661.0, "length": 350, "protein_name": "Melatonin receptor type 1A-A", "gene_name": "mtnr1aa", "organism": "Zebrafish", "refseq_name": "melatonin receptor type 1A-A", "refseq_ac": [ { "id": "NP_571468", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571468", "type": "external" } ], "gene_names_uniprotkb": "mtnr1aa; mel1ar; mtnr1ar; zgc:110628", "gene_names_refseq": "mel1ar; mt1; mtnr1aa; mtnr1ar; zgc:110628", "protein_names_uniprotkb": "Melatonin receptor type 1A-A; Mel-1A-R-A; Mel1a receptor A; Melatonin receptor Mel1a Z1.7-4; zMel1a1", "protein_names_refseq": "mel-1A-R-A; mel-1A-R; mel1a receptor A; melatonin receptor Mel1a Z1.7-4; melatonin receptor type 1A z1.7; melatonin receptor type 1A-A; zMel1a1", "tax_id": 7955, "disease": "idiopathic juvenile osteoporosis (Disease Ontology:DOID:12559); Huntington's disease (Disease Ontology:DOID:12858); acute pancreatitis (Disease Ontology:DOID:2913); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dre:30667); (R-DRE-373076); (R-DRE-418594)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "17622340;7576645", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC092957.1, BC164166.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505375 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC092957.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q567Z2;Q804J0", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0008502 melatonin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0048511 rhythmic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P51046-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P51049-1", "uniprot_id": [ { "id": "MR1BB_DANRE", "url": "https://www.uniprot.org/uniprot/P51049", "type": "external" } ], "mass": 38979.0, "length": 347, "protein_name": "Melatonin receptor type 1B-B", "gene_name": "mtnr1bb", "organism": "Zebrafish", "refseq_name": "melatonin receptor type 1B-B", "refseq_ac": [ { "id": "NP_571469", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571469", "type": "external" } ], "gene_names_uniprotkb": "mtnr1bb; mel1br; mtnr1br-2; mtnr1br; si:ch211-214k5.4; si:ch211-224h1.2", "gene_names_refseq": "Mel1b-1; mel-1B-R-B; mel-1B-R; mel1br; mtnr1bb; mtnr1br-2", "protein_names_uniprotkb": "Melatonin receptor type 1B-B; Mel-1B-R-B; Mel1b receptor B; Melatonin receptor Mel1b Z2.6-4; zMel1b-1", "protein_names_refseq": "mel1b receptor B; melatonin receptor 1B b; melatonin receptor Mel1b Z2.6-4; melatonin receptor type 1B z2.6; melatonin receptor type 1B-B; zMel1b-1", "tax_id": 7955, "disease": "acute pancreatitis (Disease Ontology:DOID:2913); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dre:30668); (R-DRE-373076); (R-DRE-418594)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "17622340;23594743;7576645", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AY166826.1, SRR32588721.4464665.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000010.1. On or before Nov 29, 2014 this sequence version replaced NP_001188494.1, XP_709805.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q5RGH4;Q804I8", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0008502 melatonin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0050796 regulation of insulin secretion;GO:0048511 rhythmic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P51049-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P52889-1", "uniprot_id": [ { "id": "LHX5_DANRE", "url": "https://www.uniprot.org/uniprot/P52889", "type": "external" } ], "mass": 44513.0, "length": 399, "protein_name": "LIM/homeobox protein Lhx5", "gene_name": "lhx5", "organism": "Zebrafish", "refseq_name": "LIM/homeobox protein Lhx5", "refseq_ac": [ { "id": "NP_571293", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571293", "type": "external" } ], "gene_names_uniprotkb": "lhx5; lim5", "gene_names_refseq": "lhx5; lim5", "protein_names_uniprotkb": "LIM/homeobox protein Lhx5; Homeobox protein LIM-5; LIM homeobox protein 5", "protein_names_refseq": "LIM homeobox protein 5; LIM/homeobox protein Lhx5; homeobox protein LIM-5", "tax_id": 7955, "disease": "", "pathway": " (dre:30465)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "7649385", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: L42547.1, BC098523.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L42547.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Probably involved in the patterning of the nervous system, in particular in the early specification of the diencephalon., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4KMK6", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030900 forebrain development;GO:0030182 neuron differentiation;GO:0001654 eye development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P52889-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P58368-1", "uniprot_id": [ { "id": "ANKHB_DANRE", "url": "https://www.uniprot.org/uniprot/P58368", "type": "external" } ], "mass": 55417.0, "length": 501, "protein_name": "Progressive ankylosis protein homolog B", "gene_name": "ankhb", "organism": "Zebrafish", "refseq_name": "progressive ankylosis protein homolog B", "refseq_ac": [ { "id": "NP_919351", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_919351", "type": "external" } ], "gene_names_uniprotkb": "ankhb; ankh; si:dkeyp-106c5.1", "gene_names_refseq": "ankhb; ankh; wu:fc08d03", "protein_names_uniprotkb": "Progressive ankylosis protein homolog B; ANK-B", "protein_names_refseq": "ANK-B; ankylosis, progressive homolog b; progressive ankylosis protein homolog B", "tax_id": 7955, "disease": "craniometaphyseal dysplasia (Disease Ontology:DOID:0080033); autosomal dominant craniometaphyseal dysplasia (Disease Ontology:DOID:0080801); chondrocalcinosis (Disease Ontology:DOID:1156)", "pathway": " (dre:323738); (R-DRE-5223345)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "11326272;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AJ302035.1, BC081575.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ302035.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B0UY66;Q66I27", "ec_number_list": [], "go_molecular_function": "GO:0005315 phosphate transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0030500 regulation of bone mineralization;GO:0035435 phosphate ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P58368-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P59679-1", "uniprot_id": [ { "id": "ARP8_DANRE", "url": "https://www.uniprot.org/uniprot/P59679", "type": "external" } ], "mass": 70133.0, "length": 623, "protein_name": "Actin-related protein 8", "gene_name": "actr8", "organism": "Zebrafish", "refseq_name": "actin-related protein 8", "refseq_ac": [ { "id": "NP_001001400", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001400", "type": "external" } ], "gene_names_uniprotkb": "actr8; wu:fe37a08; wu:fi27e09; zgc:55313", "gene_names_refseq": "actr8; wu:fe37a08; wu:fi27e09; zgc:55313", "protein_names_uniprotkb": "Actin-related protein 8", "protein_names_refseq": "ARP8 actin related protein 8 homolog; actin-related protein 8", "tax_id": 7955, "disease": "", "pathway": " (dre:326866); (R-DRE-5689603); (R-DRE-5696394)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC044364.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC044364.1. On Jul 6, 2005 this sequence version replaced XP_701378.1., [RefSeq]; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Required for the recruitment of INO80 (and probably the INO80 complex) to sites of DNA damage Strongly prefer nucleosomes and H3-H4 tetramers over H2A-H2B dimers, suggesting it may act as a nucleosome recognition module within the complex (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0005524 ATP binding", "go_cellular_component": "GO:0031011 Ino80 complex", "go_biological_process": "GO:0006310 DNA recombination;GO:0006351 DNA-templated transcription;GO:0051301 cell division;GO:0006355 regulation of DNA-templated transcription;GO:0006302 double-strand break repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "P59679-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P59845-1", "uniprot_id": [ { "id": "VACHB_DANRE", "url": "https://www.uniprot.org/uniprot/P59845", "type": "external" } ], "mass": 53052.0, "length": 493, "protein_name": "Probable vesicular acetylcholine transporter-B", "gene_name": "slc18a3b", "organism": "Zebrafish", "refseq_name": "probable vesicular acetylcholine transporter-B", "refseq_ac": [ { "id": "NP_957401", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957401", "type": "external" } ], "gene_names_uniprotkb": "slc18a3b; slc18a3; vacht; zgc:64220", "gene_names_refseq": "Slc18a3; VAChT-B; slc18a3b; zgc:64220", "protein_names_uniprotkb": "Probable vesicular acetylcholine transporter-B; Solute carrier family 18 member 3-B; VAChT-B", "protein_names_refseq": "VAChT; probable vesicular acetylcholine transporter-B; probable vesicular acetylcholine transporter; solute carrier family 18 (vesicular acetylcholine transporter), member 3b; solute carrier family 18 (vesicular acetylcholine), member 3b; solute carrier family 18 member 3-B; solute carrier family 18 member 3; vachtb; vchat; vesicular acetylcholine transporter b; zSlc18a3", "tax_id": 7955, "disease": "congenital myasthenic syndrome 21 (Disease Ontology:DOID:0110672); Alzheimer's disease (Disease Ontology:DOID:10652); Huntington's disease (Disease Ontology:DOID:12858); asthma (Disease Ontology:DOID:2841); bladder disease (Disease Ontology:DOID:365)", "pathway": " (dre:394082)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC054646.1 [ECO:0000332] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC054646.1. On Aug 31, 2013 this sequence version replaced XP_005173071.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Involved in acetylcholine transport into synaptic vesicles., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005277 acetylcholine transmembrane transporter activity", "go_cellular_component": "GO:0043195 terminal bouton;GO:0030122 AP-2 adaptor complex;GO:0030121 AP-1 adaptor complex", "go_biological_process": "GO:0007268 chemical synaptic transmission;GO:0051649 establishment of localization in cell;GO:0006837 serotonin transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "P59845-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P61485-1", "uniprot_id": [ { "id": "RL36A_DANRE", "url": "https://www.uniprot.org/uniprot/P61485", "type": "external" } ], "mass": 12528.0, "length": 106, "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "rpl36a", "organism": "Zebrafish", "refseq_name": "large ribosomal subunit protein eL42", "refseq_ac": [ { "id": "NP_001189439", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189439", "type": "external" } ], "gene_names_uniprotkb": "rpl36a", "gene_names_refseq": "bbr; rl44; rpl36a", "protein_names_uniprotkb": "Large ribosomal subunit protein eL42; 60S ribosomal protein L36a", "protein_names_refseq": "60S ribosomal protein L36a; 60S ribosomal protein L44; bubble brain; large ribosomal subunit protein eL42", "tax_id": 7955, "disease": "", "pathway": " (dre:195819); (R-DRE-156827); (R-DRE-1799339); (R-DRE-6791226); (R-DRE-72689); (R-DRE-975956); (R-DRE-975957); (R-DRE-9954709); (R-DRE-9954714); (R-DRE-9954716)", "pathway_count": 10, "publication_count": 1, "publication_id_list": "40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC055187.1, EH550703.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH538908.1 and EH571835.1. On Jun 29, 2012 this sequence version replaced NP_775369.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q90VX4", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation;GO:0051726 regulation of cell cycle;GO:0043009 chordate embryonic development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P61485-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P62084-1", "uniprot_id": [ { "id": "RS7_DANRE", "url": "https://www.uniprot.org/uniprot/P62084", "type": "external" } ], "mass": 22250.0, "length": 194, "protein_name": "Small ribosomal subunit protein eS7", "gene_name": "rps7", "organism": "Zebrafish", "refseq_name": "small ribosomal subunit protein eS7", "refseq_ac": [ { "id": "NP_957046", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957046", "type": "external" } ], "gene_names_uniprotkb": "rps7; zgc:73216", "gene_names_refseq": "rps7; zgc:73216", "protein_names_uniprotkb": "Small ribosomal subunit protein eS7; 40S ribosomal protein S7", "protein_names_refseq": "40S ribosomal protein S7; small ribosomal subunit protein eS7", "tax_id": 7955, "disease": "Diamond-Blackfan anemia 8 (Disease Ontology:DOID:0111881)", "pathway": " (dre:393725); (R-DRE-156827); (R-DRE-1799339); (R-DRE-6791226); (R-DRE-72649); (R-DRE-72689); (R-DRE-72695); (R-DRE-72702); (R-DRE-975956); (R-DRE-975957); (R-DRE-9954714); (R-DRE-9954716)", "pathway_count": 12, "publication_count": 3, "publication_id_list": "15138505;23594743;40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: CK016355.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505375 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC059562.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Required for rRNA maturation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005813 centrosome;GO:0032040 small-subunit processome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0030097 hemopoiesis;GO:0006412 translation;GO:0006364 rRNA processing;GO:0051726 regulation of cell cycle;GO:0043009 chordate embryonic development", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P62084-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P79724-2", "uniprot_id": [ { "id": "HXADB_DANRE", "url": "https://www.uniprot.org/uniprot/P79724", "type": "external" } ], "mass": 32396.0, "length": 289, "protein_name": "Homeobox protein Hox-A13b", "gene_name": "hoxa13b", "organism": "Zebrafish", "refseq_name": "homeobox protein Hox-A13b", "refseq_ac": [ { "id": "NP_571269", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571269", "type": "external" } ], "gene_names_uniprotkb": "hoxa13b; hoxa-13; hoxa13; zgc:110514", "gene_names_refseq": "HOXA13; Hoxa-13; hoxa13b; wu:fa66g07; zgc:110514", "protein_names_uniprotkb": "Homeobox protein Hox-A13b; Hox-A13", "protein_names_refseq": "homeo box A13b; homeobox gene A-13b; homeobox protein Hox-A13b; hox-A13", "tax_id": 7955, "disease": "hand-foot-genital syndrome (Disease Ontology:DOID:0060739); Guttmacher syndrome (Disease Ontology:DOID:0111544); hypospadias (Disease Ontology:DOID:10892)", "pathway": " (dre:30438)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "8951794;9831563", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC090761.1, EV762052.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC090761.1. On or before Jun 18, 2015 this sequence version replaced XP_005158012.1, NP_571269.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5CZP9;Q9PWL4", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0033333 fin development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P79724-2", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P83758-1", "uniprot_id": [ { "id": "DMT3A_DANRE", "url": "https://www.uniprot.org/uniprot/P83758", "type": "external" } ], "mass": 48965.0, "length": 448, "protein_name": "Doublesex- and mab-3-related transcription factor 3a", "gene_name": "dmrt3a", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "dmrt3a; si:dkeyp-31e5.2; zgc:101766", "gene_names_refseq": "", "protein_names_uniprotkb": "Doublesex- and mab-3-related transcription factor 3a; Dmrt7a", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:450035)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "11932949;18282142;23594743", "class_list": "", "function": "Probable transcription factor that plays a role in configuring the spinal circuits controlling motion in vertebrates. Involved in neuronal specification within specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling movements. May regulate transcription (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A2BFC1;Q4VUS9;Q5XJM6;Q694V7;Q9DD75", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0008344 adult locomotory behavior;GO:0007548 sex differentiation;GO:0036269 swimming behavior", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P83758-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "P86347-1", "uniprot_id": [ { "id": "BORE2_DANRE", "url": "https://www.uniprot.org/uniprot/P86347", "type": "external" } ], "mass": 28638.0, "length": 255, "protein_name": "Borealin-2", "gene_name": "cdca9", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "cdca9; Dasra A; Dasra-A; cdca8.2", "gene_names_refseq": "", "protein_names_uniprotkb": "Borealin-2; Cell division cycle-associated protein 8.2; Cell division cycle-associated protein 9; Dasra-A; DrDasraA", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "15260989", "class_list": "", "function": "Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0051233 spindle midzone;GO:0000775 chromosome, centromeric region;GO:0032133 chromosome passenger complex", "go_biological_process": "GO:0051301 cell division;GO:0000070 mitotic sister chromatid segregation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P86347-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q00IB7-1", "uniprot_id": [ { "id": "PKHH1_DANRE", "url": "https://www.uniprot.org/uniprot/Q00IB7", "type": "external" } ], "mass": 160045.0, "length": 1433, "protein_name": "Pleckstrin homology domain-containing family H member 1", "gene_name": "plekhh1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "plekhh1; im:6897489; im:7143671; max1", "gene_names_refseq": "", "protein_names_uniprotkb": "Pleckstrin homology domain-containing family H member 1; PH domain-containing family H member 1; Protein max-1 homolog", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:565914)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "17065323", "class_list": "", "function": "Critical component of the guidance pathway underlying endothelial cell migration and blood vessel patterning. Involved in mediating membrane localization of ephrin proteins, which have been shown to provide guidance cues for endothelial cell migration., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005856 cytoskeleton", "go_biological_process": "GO:0048514 blood vessel morphogenesis;GO:0001569 branching involved in blood vessel morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q00IB7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q01703-1", "uniprot_id": [ { "id": "MSXC_DANRE", "url": "https://www.uniprot.org/uniprot/Q01703", "type": "external" } ], "mass": 30186.0, "length": 273, "protein_name": "Homeobox protein MSH-C", "gene_name": "msx3; msxc", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "msx3; msxc; homeobox; msh-C; msh-c; mshC; msx-c; msxc; zgc:86596", "gene_names_refseq": "", "protein_names_uniprotkb": "Homeobox protein MSH-C", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:30526)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "1352984;1673109;33036919;33722902;34518542;36636913;38812038;7588061;7768177;8565830;8903357;9335141", "class_list": "", "function": "Involved in the development of the inner ear., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0048598 embryonic morphogenesis;GO:0043049 otic placode formation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q01703-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q03357-1", "uniprot_id": [ { "id": "MSXA_DANRE", "url": "https://www.uniprot.org/uniprot/Q03357", "type": "external" } ], "mass": 29117.0, "length": 257, "protein_name": "Homeobox protein MSH-A", "gene_name": "msxa", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "msxa; msh-a", "gene_names_refseq": "", "protein_names_uniprotkb": "Homeobox protein MSH-A", "protein_names_refseq": "", "tax_id": 7955, "disease": "parietal foramina (Disease Ontology:DOID:0060285); craniosynostosis 2 (Disease Ontology:DOID:0061009); hypertension (Disease Ontology:DOID:10763); craniosynostosis (Disease Ontology:DOID:2340)", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "1673109;7768177", "class_list": "", "function": "Probable morphogenetic role., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0048598 embryonic morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q03357-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q04475-1", "uniprot_id": [ { "id": "B2MG_DANRE", "url": "https://www.uniprot.org/uniprot/Q04475", "type": "external" } ], "mass": 13289.0, "length": 116, "protein_name": "Beta-2-microglobulin", "gene_name": "b2m", "organism": "Zebrafish", "refseq_name": "beta-2-microglobulin precursor", "refseq_ac": [ { "id": "NP_001153240", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153240", "type": "external" } ], "gene_names_uniprotkb": "b2m", "gene_names_refseq": "b2m; bwm; wu:fa94c05; wu:fb10a09", "protein_names_uniprotkb": "Beta-2-microglobulin", "protein_names_refseq": "beta-2-microglobulin precursor", "tax_id": 7955, "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589); peripheral artery disease (Disease Ontology:DOID:0050830); lymphoproliferative syndrome (Disease Ontology:DOID:0060704); immunodeficiency 43 (Disease Ontology:DOID:0111981); hypertension (Disease Ontology:DOID:10763); pyelonephritis (Disease Ontology:DOID:11400); Parkinson's disease (Disease Ontology:DOID:14330); arteriosclerosis (Disease Ontology:DOID:2349); hemochromatosis (Disease Ontology:DOID:2352); acute kidney failure (Disease Ontology:DOID:3021); carotid artery disease (Disease Ontology:DOID:3407); autoimmune disease (Disease Ontology:DOID:417); ureteral obstruction (Disease Ontology:DOID:5199); proteinuria (Disease Ontology:DOID:576); encephalomyelitis (Disease Ontology:DOID:640); cataract (Disease Ontology:DOID:83); arthritis (Disease Ontology:DOID:848); measles (Disease Ontology:DOID:8622); type 2 diabetes mellitus (Disease Ontology:DOID:9352); multiple myeloma (Disease Ontology:DOID:9538); obesity (Disease Ontology:DOID:9970)", "pathway": " (dre:30400); (R-DRE-2132295)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "40044042;8462988", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC162435.1, DN894491.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476748, SAMEA4476750 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1 and BC162435.1. Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 21, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0023026 MHC class II protein complex binding;GO:0042605 peptide antigen binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0042613 MHC class II protein complex;GO:0042612 MHC class I protein complex", "go_biological_process": "GO:0006955 immune response;GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0002474 antigen processing and presentation of peptide antigen via MHC class I;GO:0002503 peptide antigen assembly with MHC class II protein complex;GO:0050870 positive regulation of T cell activation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q04475-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q04896-1", "uniprot_id": [ { "id": "HME1A_DANRE", "url": "https://www.uniprot.org/uniprot/Q04896", "type": "external" } ], "mass": 26200.0, "length": 231, "protein_name": "Homeobox protein engrailed-1a", "gene_name": "eng1a", "organism": "Zebrafish", "refseq_name": "homeobox protein engrailed-1a", "refseq_ac": [ { "id": "NP_571120", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571120", "type": "external" } ], "gene_names_uniprotkb": "eng1a; eng-1; eng1", "gene_names_refseq": "ENG-1; en-1; en1a; en1; eng1a; eng1; zgc:100771", "protein_names_uniprotkb": "Homeobox protein engrailed-1a; Homeobox protein en-1a", "protein_names_refseq": "engrailed 1a; homeobox protein en-1a; homeobox protein engrailed-1a", "tax_id": 7955, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (dre:30244)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "1363539;28807781", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC080209.1, X68445.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476761 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000009.1. On Apr 11, 2018 this sequence version replaced NP_571120.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Engrailed plays an evolutionarily conserved role in the separate innervation of vertebrate epaxial-hypaxial muscle., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0030182 neuron differentiation;GO:0060385 axonogenesis involved in innervation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q04896-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q05AK5-1", "uniprot_id": [ { "id": "MYLIB_DANRE", "url": "https://www.uniprot.org/uniprot/Q05AK5", "type": "external" } ], "mass": 52661.0, "length": 464, "protein_name": "E3 ubiquitin-protein ligase MYLIP-B", "gene_name": "mylipb", "organism": "Zebrafish", "refseq_name": "E3 ubiquitin-protein ligase MYLIP-B", "refseq_ac": [ { "id": "NP_001073491", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073491", "type": "external" } ], "gene_names_uniprotkb": "mylipb; zgc:153767", "gene_names_refseq": "mylipb; zgc:153767", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase MYLIP-B; 2.3.2.27; MIR-B; Myosin regulatory light chain-interacting protein B; RING-type E3 ubiquitin transferase MYLIP-B", "protein_names_refseq": "E3 ubiquitin-protein ligase MYLIP-B; MIR-B; RING-type E3 ubiquitin transferase MYLIP-B; myosin regulatory light chain-interacting protein B", "tax_id": 7955, "disease": "neurodegenerative disease (Disease Ontology:DOID:1289)", "pathway": " (dre:565911)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "38739631", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124450.1, BC165740.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC124450.1. On Mar 11, 2007 this sequence version replaced XP_694265.1., [RefSeq]; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC). Regulates cell movements during gastrulation by acting downstream of fz7 to antagonize the frizzled-signaling pathway (By similarity)., [UniProtKB]; Zebrafish mylipb attenuates antiviral innate immunity through two synergistic mechanisms targeting transcription factor irf3. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0030178 negative regulation of Wnt signaling pathway;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0007369 gastrulation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q05AK5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q05AL2-1", "uniprot_id": [ { "id": "PPM1H_DANRE", "url": "https://www.uniprot.org/uniprot/Q05AL2", "type": "external" } ], "mass": 56561.0, "length": 516, "protein_name": "Protein phosphatase 1H", "gene_name": "ppm1h", "organism": "Zebrafish", "refseq_name": "protein phosphatase 1H", "refseq_ac": [ { "id": "NP_001070923", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070923", "type": "external" } ], "gene_names_uniprotkb": "ppm1h; zgc:153678", "gene_names_refseq": "ppm1h; zgc:153678", "protein_names_uniprotkb": "Protein phosphatase 1H; 3.1.3.16", "protein_names_refseq": "protein phosphatase 1H", "tax_id": 7955, "disease": "", "pathway": " (dre:768291)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124421.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC124421.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" } ], "go_molecular_function": "GO:0004741 [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity;GO:0004721 phosphoprotein phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q05AL2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08BB1-1", "uniprot_id": [ { "id": "EFGM_DANRE", "url": "https://www.uniprot.org/uniprot/Q08BB1", "type": "external" } ], "mass": 82749.0, "length": 745, "protein_name": "Elongation factor G, mitochondrial", "gene_name": "gfm1", "organism": "Zebrafish", "refseq_name": "elongation factor G, mitochondrial", "refseq_ac": [ { "id": "NP_001073463", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073463", "type": "external" } ], "gene_names_uniprotkb": "gfm1; efg1; zgc:154041", "gene_names_refseq": "fc96f12; gfm1; wu:fc96f12; zgc:154041", "protein_names_uniprotkb": "Elongation factor G, mitochondrial; 3.6.5.-; EF-Gmt; Elongation factor G 1, mitochondrial; Elongation factor G1; mEF-G 1", "protein_names_refseq": "elongation factor G, mitochondrial", "tax_id": 7955, "disease": "combined oxidative phosphorylation deficiency 1 (Disease Ontology:DOID:0111474)", "pathway": " (dre:561840); (R-DRE-5389840)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124798.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505380 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC124798.1. On Mar 11, 2007 this sequence version replaced XP_690332.2., [RefSeq]; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.1.1.29", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.29", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0003746 translation elongation factor activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0070125 mitochondrial translational elongation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q08BB1-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08BB3-1", "uniprot_id": [ { "id": "DCA12_DANRE", "url": "https://www.uniprot.org/uniprot/Q08BB3", "type": "external" } ], "mass": 53871.0, "length": 482, "protein_name": "DDB1- and CUL4-associated factor 12", "gene_name": "dcaf12", "organism": "Zebrafish", "refseq_name": "DDB1- and CUL4-associated factor 12", "refseq_ac": [ { "id": "NP_001071048", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071048", "type": "external" } ], "gene_names_uniprotkb": "dcaf12; wdr40a; zgc:154031", "gene_names_refseq": "dcaf12; wdr40a; wu:fb93d04; zgc:154031", "protein_names_uniprotkb": "DDB1- and CUL4-associated factor 12; WD repeat-containing protein 40A", "protein_names_refseq": "DDB1- and CUL4-associated factor 12; WD repeat-containing protein 40A", "tax_id": 7955, "disease": "", "pathway": " (dre:570671)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124796.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC124796.1. On Nov 9, 2006 this sequence version replaced XP_699269.1., [RefSeq]; Substrate-recognition component of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation. The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms. The DCX(DCAF12) complex specifically recognizes proteins with a diglutamate (Glu-Glu) at the C-terminus leading to their ubiquitination and degradation. Also directly recognizes the C-terminal glutamate-leucine (Glu-Leu) degron as an alternative degron in proteins leading to their ubiquitination and degradation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0080008 Cul4-RING E3 ubiquitin ligase complex", "go_biological_process": "GO:0010506 regulation of autophagy;GO:0016567 protein ubiquitination;GO:0140627 ubiquitin-dependent protein catabolic process via the C-end degron rule pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q08BB3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08BH5-1", "uniprot_id": [ { "id": "RBM46_DANRE", "url": "https://www.uniprot.org/uniprot/Q08BH5", "type": "external" } ], "mass": 56959.0, "length": 510, "protein_name": "Probable RNA-binding protein 46", "gene_name": "rbm46", "organism": "Zebrafish", "refseq_name": "probable RNA-binding protein 46", "refseq_ac": [ { "id": "NP_001073493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073493", "type": "external" } ], "gene_names_uniprotkb": "rbm46; fe11d09; wu:fe11d09; zgc:153695", "gene_names_refseq": "fe11d09; rbm46; wu:fe11d09; zgc:153695", "protein_names_uniprotkb": "Probable RNA-binding protein 46; RNA-binding motif protein 46", "protein_names_refseq": "probable RNA-binding protein 46", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "23594743;33524105", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124720.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898400, SAMN18715719 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC124720.1. On Oct 5, 2011 this sequence version replaced NP_001073493.1. Sequence Note: This RefSeq record was created from a transcript of a different strain than the reference genome strain because no single transcript from the reference strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data., [RefSeq]; Essential for male and female fertility, playing a crucial role in regulating germ cell development by ensuring the proper progression of meiosis prophase I., [UniProtKB, PubMed]; Rbm46, a novel germ cell-specific factor, modulates meiotic progression and spermatogenesis., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0007283 spermatogenesis;GO:0048477 oogenesis;GO:0051321 meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q08BH5-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08BM0-1", "uniprot_id": [ { "id": "TM10B_DANRE", "url": "https://www.uniprot.org/uniprot/Q08BM0", "type": "external" } ], "mass": 35580.0, "length": 310, "protein_name": "tRNA methyltransferase 10 homolog B", "gene_name": "trmt10b", "organism": "Zebrafish", "refseq_name": "tRNA methyltransferase 10 homolog B isoform 1", "refseq_ac": [ { "id": "NP_001070749", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070749", "type": "external" } ], "gene_names_uniprotkb": "trmt10b; rg9mtd3; zgc:153341", "gene_names_refseq": "rg9mtd3; trmt10b; zgc:153341", "protein_names_uniprotkb": "tRNA methyltransferase 10 homolog B; 2.1.1.221; RNA (guanine-9-)-methyltransferase domain-containing protein 3; tRNA (guanine(9)-N(1))-methyltransferase TRMT10B", "protein_names_refseq": "RNA (guanine-9-)-methyltransferase domain-containing protein 3-like; tRNA (guanine(9)-N(1))-methyltransferase TRMT10B; tRNA methyltransferase 10 homolog B isoform 1", "tax_id": 7955, "disease": "", "pathway": " (dre:768135)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01045209.1, SRR5865381.31995.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Jun 26, 2025 this sequence version replaced NP_001070749.1., [RefSeq]; S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in tRNAs. Probably not able to catalyze formation of N(1)-methyladenine at position 9 (m1A9) in tRNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.218", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.218", "type": "external" }, { "id": "2.1.1.221", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.221", "type": "external" } ], "go_molecular_function": "GO:0000049 tRNA binding;GO:0052905 tRNA (guanosine(9)-N1)-methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0002939 tRNA N1-guanine methylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q08BM0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08BU8-1", "uniprot_id": [ { "id": "R7BPA_DANRE", "url": "https://www.uniprot.org/uniprot/Q08BU8", "type": "external" } ], "mass": 27877.0, "length": 248, "protein_name": "Regulator of G protein signaling 7-binding protein A", "gene_name": "rgs7bpa", "organism": "Zebrafish", "refseq_name": "regulator of G-protein signaling 7-binding protein A", "refseq_ac": [ { "id": "NP_001070076", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070076", "type": "external" } ], "gene_names_uniprotkb": "rgs7bpa; si:dkey-250l23.3; zgc:154140", "gene_names_refseq": "rgs7bpa; zgc:154140", "protein_names_uniprotkb": "Regulator of G protein signaling 7-binding protein A; R7 family-binding protein A", "protein_names_refseq": "R7 family-binding protein A; regulator of G-protein signaling 7-binding protein A", "tax_id": 7955, "disease": "", "pathway": " (dre:767669)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124550.1, BC165108.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505372, SAMEA3505376 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC124550.1., [RefSeq]; Regulator of G protein-coupled receptor (GPCR) signaling. Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellular location of the R7-Gbeta5 complexes. When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits. When it is unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cytoplasmic shuttling (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B0S6X3", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0098794 postsynapse;GO:0043005 neuron projection", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0009968 negative regulation of signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q08BU8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08BV2-1", "uniprot_id": [ { "id": "TYW5_DANRE", "url": "https://www.uniprot.org/uniprot/Q08BV2", "type": "external" } ], "mass": 38059.0, "length": 326, "protein_name": "tRNA wybutosine-synthesizing protein 5", "gene_name": "tyw5", "organism": "Zebrafish", "refseq_name": "tRNA wybutosine-synthesizing protein 5", "refseq_ac": [ { "id": "NP_001071011", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071011", "type": "external" } ], "gene_names_uniprotkb": "tyw5; zgc:154110", "gene_names_refseq": "im:7148946; m:7148946; tyw5; zgc:154110", "protein_names_uniprotkb": "tRNA wybutosine-synthesizing protein 5; 1.14.11.42; tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase", "protein_names_refseq": "jmjC domain-containing protein C2orf60 homolog; tRNA wybutosine-synthesizing protein 5; tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase", "tax_id": 7955, "disease": "", "pathway": " (dre:557725)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124543.1, EE706875.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC124543.1. On Nov 9, 2006 this sequence version replaced XP_685930.1., [RefSeq]; tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.42", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0042803 protein homodimerization activity;GO:0000049 tRNA binding;GO:0102524 tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity", "go_cellular_component": "", "go_biological_process": "GO:0031591 wybutosine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q08BV2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08BY5-1", "uniprot_id": [ { "id": "JMJD4_DANRE", "url": "https://www.uniprot.org/uniprot/Q08BY5", "type": "external" } ], "mass": 49892.0, "length": 422, "protein_name": "2-oxoglutarate and iron-dependent oxygenase JMJD4", "gene_name": "jmjd4", "organism": "Zebrafish", "refseq_name": "2-oxoglutarate and iron-dependent oxygenase JMJD4", "refseq_ac": [ { "id": "NP_001070096", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070096", "type": "external" } ], "gene_names_uniprotkb": "jmjd4; zgc:153974", "gene_names_refseq": "CH1073-162B20.2; jmjd4; zgc:153974", "protein_names_uniprotkb": "2-oxoglutarate and iron-dependent oxygenase JMJD4; 1.14.11.-; JmjC domain-containing protein 4; Jumonji domain-containing protein 4; Lysyl-hydroxylase JMJD4", "protein_names_refseq": "2-oxoglutarate and iron-dependent oxygenase JMJD4; jmjC domain-containing protein 4; jumonji domain-containing protein 4; lysyl-hydroxylase JMJD4", "tax_id": 7955, "disease": "", "pathway": " (dre:767690); (R-DRE-9629569)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124503.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC124503.1., [RefSeq]; Catalyzes the 2-oxoglutarate and iron-dependent C4-lysyl hydroxylation of ETF1 at 'Lys-63' thereby promoting the translational termination efficiency of ETF1., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0043565 sequence-specific DNA binding;GO:0016706 2-oxoglutarate-dependent dioxygenase activity;GO:0106156 peptidyl-lysine 4-dioxygenase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0045905 positive regulation of translational termination;GO:0018126 protein hydroxylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q08BY5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08C57-1", "uniprot_id": [ { "id": "FDX2_DANRE", "url": "https://www.uniprot.org/uniprot/Q08C57", "type": "external" } ], "mass": 21468.0, "length": 195, "protein_name": "Ferredoxin-2, mitochondrial", "gene_name": "fdx2", "organism": "Zebrafish", "refseq_name": "ferredoxin-2, mitochondrial precursor", "refseq_ac": [ { "id": "NP_001070132", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070132", "type": "external" } ], "gene_names_uniprotkb": "fdx2; fdx1l; zgc:153554", "gene_names_refseq": "fdx1l; fdx2; zgc:153554", "protein_names_uniprotkb": "Ferredoxin-2, mitochondrial; Adrenodoxin-like protein; Ferredoxin-1-like protein", "protein_names_refseq": "adrenodoxin-like protein, mitochondrial; ferredoxin 1-like; ferredoxin-1-like protein; ferredoxin-2, mitochondrial precursor; ferredoxin-2, mitochondrial", "tax_id": 7955, "disease": "", "pathway": " (dre:767726); (R-DRE-1362409); (R-DRE-196108); (R-DRE-211976); (R-DRE-2395516)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124384.1, GDQQ01007655.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1, EH493611.1, EH559468.1 and EH612574.1., [RefSeq]; Electron donor, of the core iron-sulfur cluster (ISC) assembly complex, that acts to reduce the persulfide into sulfide during [2Fe-2S] clusters assembly on the scaffolding protein ISCU (By similarity). The core iron-sulfur cluster (ISC) assembly complex is involved in the de novo synthesis of a [2Fe-2S] cluster, the first step of the mitochondrial iron-sulfur protein biogenesis. This process is initiated by the cysteine desulfurase complex (NFS1:LYRM4:NDUFAB1) that produces persulfide which is delivered on the scaffold protein ISCU in a FXN-dependent manner. Then this complex is stabilized by FDX2 which provides reducing equivalents to accomplish the [2Fe-2S] cluster assembly. Finally, the [2Fe-2S] cluster is transferred from ISCU to chaperone proteins, including HSCB, HSPA9 and GLRX5 (By similarity). Essential for coenzyme Q biosynthesis: together with FDXR, transfers the electrons required for the hydroxylation reaction performed by COQ6 (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0051537 2 iron, 2 sulfur cluster binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006744 ubiquinone biosynthetic process;GO:0022900 electron transport chain;GO:0044571 [2Fe-2S] cluster assembly;GO:0140647 P450-containing electron transport chain;GO:0044572 [4Fe-4S] cluster assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q08C57-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08C60-1", "uniprot_id": [ { "id": "OFUT4_DANRE", "url": "https://www.uniprot.org/uniprot/Q08C60", "type": "external" } ], "mass": 55712.0, "length": 483, "protein_name": "GDP-fucose protein O-fucosyltransferase 4", "gene_name": "pofut4", "organism": "Zebrafish", "refseq_name": "GDP-fucose protein O-fucosyltransferase 4 precursor", "refseq_ac": [ { "id": "NP_001070642", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070642", "type": "external" } ], "gene_names_uniprotkb": "pofut4; fut11; zgc:153537", "gene_names_refseq": "fut11; pofut4; zgc:153537", "protein_names_uniprotkb": "GDP-fucose protein O-fucosyltransferase 4; 2.4.1.221; Fuc-TXI; FucT-XI; Fucosyltransferase 11; Fucosyltransferase XI; Galactoside 3-L-fucosyltransferase 11", "protein_names_refseq": "GDP-fucose protein O-fucosyltransferase 4 precursor; GDP-fucose protein O-fucosyltransferase 4; alpha-(1,3)-fucosyltransferase 11; fuc-TXI; fucT-XI; fucosyltransferase 11 (alpha (1,3) fucosyltransferase); fucosyltransferase XI; galactoside 3-L-fucosyltransferase 11", "tax_id": 7955, "disease": "stomach cancer (Disease Ontology:DOID:10534)", "pathway": " (dre:568888); (R-DRE-5173105)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "glycogene;glycosyltransferase", "function": "##Evidence-Data-START## Transcript exon combination :: BC124380.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505391, SAMEA4476731 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC124380.1. On Oct 11, 2006 this sequence version replaced XP_697342.1., [RefSeq]; Protein O-fucosyltransferase that specifically catalyzes O-fucosylation of serine or threonine residues in EMI domains of target proteins. Attaches fucose through an O-glycosidic linkage. O-fucosylation of EMI domain-containing proteins may be required for facilitating protein folding and secretion., [UniProtKB, UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.221", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.221", "type": "external" }, { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" } ], "go_molecular_function": "GO:0046922 peptide-O-fucosyltransferase activity;GO:0046920 alpha-(1->3)-fucosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0050714 positive regulation of protein secretion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q08C60-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000010000.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08C75-1", "uniprot_id": [ { "id": "VACHA_DANRE", "url": "https://www.uniprot.org/uniprot/Q08C75", "type": "external" } ], "mass": 55760.0, "length": 513, "protein_name": "Probable vesicular acetylcholine transporter-A", "gene_name": "slc18a3a", "organism": "Zebrafish", "refseq_name": "probable vesicular acetylcholine transporter-A", "refseq_ac": [ { "id": "NP_001071018", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071018", "type": "external" } ], "gene_names_uniprotkb": "slc18a3a; si:ch211-232k3.4; zgc:153442", "gene_names_refseq": "VAChT-A; slc18a3a; zgc:153442", "protein_names_uniprotkb": "Probable vesicular acetylcholine transporter-A; Solute carrier family 18 member 3-A; VAChT-A", "protein_names_refseq": "probable vesicular acetylcholine transporter-A; solute carrier family 18 (vesicular acetylcholine transporter), member 3a; solute carrier family 18 (vesicular acetylcholine), member 3a; vachta; vesicular acetylcholine transporter a", "tax_id": 7955, "disease": "congenital myasthenic syndrome 21 (Disease Ontology:DOID:0110672); Alzheimer's disease (Disease Ontology:DOID:10652); Huntington's disease (Disease Ontology:DOID:12858); asthma (Disease Ontology:DOID:2841); bladder disease (Disease Ontology:DOID:365)", "pathway": " (dre:559347); (R-DRE-264642); (R-DRE-8856825)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124354.1 [ECO:0000332] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC124354.1. On Nov 9, 2006 this sequence version replaced XP_687773.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Involved in acetylcholine transport into synaptic vesicles., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005277 acetylcholine transmembrane transporter activity", "go_cellular_component": "GO:0043195 terminal bouton;GO:0030122 AP-2 adaptor complex;GO:0030121 AP-1 adaptor complex", "go_biological_process": "GO:0007268 chemical synaptic transmission;GO:0051649 establishment of localization in cell;GO:0006837 serotonin transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q08C75-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08C92-1", "uniprot_id": [ { "id": "TYW1_DANRE", "url": "https://www.uniprot.org/uniprot/Q08C92", "type": "external" } ], "mass": 83549.0, "length": 730, "protein_name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1", "gene_name": "tyw1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "tyw1; im:6898509; rsafd1; wu:fb74d01; zgc:153368", "gene_names_refseq": "", "protein_names_uniprotkb": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1; 4.1.3.44; Radical S-adenosyl methionine and flavodoxin domain-containing protein 1; tRNA wybutosine-synthesizing protein 1 homolog; tRNA-yW-synthesizing protein", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:562076)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the biosynthesis of wybutosine, a hyper modified guanosine with a tricyclic base located at position 37 of eukaryotic phenylalanine tRNA (tRNA(Phe)) that contributes to maintenance of the translational reading frame. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis., [UniProtKB, UniProtKB]; Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.1.3.44", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.3.44", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0010181 FMN binding;GO:0102521 tRNA-4-demethylwyosine synthase activity", "go_cellular_component": "", "go_biological_process": "GO:0031591 wybutosine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q08C92-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08C99-1", "uniprot_id": [ { "id": "VRTN_DANRE", "url": "https://www.uniprot.org/uniprot/Q08C99", "type": "external" } ], "mass": 77732.0, "length": 677, "protein_name": "Vertnin", "gene_name": "vrtn", "organism": "Zebrafish", "refseq_name": "vertnin", "refseq_ac": [ { "id": "NP_001070608", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070608", "type": "external" } ], "gene_names_uniprotkb": "vrtn; si:ch211-146n9.1; si:dkey-1h6.4; zgc:153349", "gene_names_refseq": "vrtn; zgc:153349", "protein_names_uniprotkb": "Vertnin", "protein_names_refseq": "vertebrae development homolog (pig); vertnin", "tax_id": 7955, "disease": "", "pathway": " (dre:555269)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;28928283", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124324.1, BC085531.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476772, SAMEA4476804 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC124324.1. On Oct 11, 2006 this sequence version replaced XP_682829.1., [RefSeq]; Functions as a transcriptional repressor that modulates bmp2b expression during dorsoventral patterning., [UniProtKB, PubMed]; Vrtn binds a bmp2b regulatory sequence and acts as a repressor to inhibit its zygotic transcription., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A5PMA1;B0R0J2", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q08C99-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08CD9-1", "uniprot_id": [ { "id": "HAUS3_DANRE", "url": "https://www.uniprot.org/uniprot/Q08CD9", "type": "external" } ], "mass": 70841.0, "length": 629, "protein_name": "HAUS augmin-like complex subunit 3", "gene_name": "haus3", "organism": "Zebrafish", "refseq_name": "HAUS augmin-like complex subunit 3", "refseq_ac": [ { "id": "NP_001070639", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070639", "type": "external" } ], "gene_names_uniprotkb": "haus3; Zgc:153228", "gene_names_refseq": "haus3; wu:fb93e07; wu:fd19a03; zgc:153228", "protein_names_uniprotkb": "HAUS augmin-like complex subunit 3; Protein samba", "protein_names_refseq": "HAUS augmin-like complex subunit 3; augmin-like complex subunit 3-like protein alpha; augmin-like complex subunit 3-like protein beta; samba", "tax_id": 7955, "disease": "", "pathway": " (dre:566923); (R-DRE-380320)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "21228005;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BK006950.1, BC124280.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476746, SAMEA4476749 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1, BC124280.1 and BM316781.1. On Oct 11, 2006 this sequence version replaced XP_695301.1., [RefSeq]; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex., [UniProtKB, UniProtKB]; Positional cloning reveals that Rumba is a novel nuclear C2H2 zinc-finger factor with unknown function and samba encodes an evolutionarily conserved protein that is homologous to human augmin complex subunit 3 (HAUS3)., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0I9QPY6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005813 centrosome;GO:0005874 microtubule;GO:0005815 microtubule organizing center;GO:0070652 HAUS complex;GO:0072686 mitotic spindle", "go_biological_process": "GO:0051301 cell division;GO:0060216 definitive hemopoiesis;GO:0051225 spindle assembly;GO:0031023 microtubule organizing center organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q08CD9-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08CH3-1", "uniprot_id": [ { "id": "MPND_DANRE", "url": "https://www.uniprot.org/uniprot/Q08CH3", "type": "external" } ], "mass": 51102.0, "length": 458, "protein_name": "MPN domain-containing protein", "gene_name": "mpnd", "organism": "Zebrafish", "refseq_name": "MPN domain-containing protein", "refseq_ac": [ { "id": "NP_001070033", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070033", "type": "external" } ], "gene_names_uniprotkb": "mpnd; fj55b03; wu:fj55b03; zgc:153076", "gene_names_refseq": "fj55b03; mpnd; wu:fj55b03; zgc:153076", "protein_names_uniprotkb": "MPN domain-containing protein; 3.4.-.-", "protein_names_refseq": "MPN domain-containing protein", "tax_id": 7955, "disease": "", "pathway": " (dre:559169)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124239.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC124239.1. On Oct 4, 2006 this sequence version replaced XP_687577.1., [RefSeq]; Probable protease (By similarity). Acts as a sensor of N(6)-methyladenosine methylation on DNA (m6A): recognizes and binds m6A DNA, leading to its degradation (By similarity). Binds only double strand DNA (dsDNA) in a sequence-independent manner (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Probable protease. Acts as a sensor of N(6)-methyladenosine methylation on DNA (m6A): recognizes and binds m6A DNA, leading to its degradation. Binds only double strand DNA (dsDNA) in a sequence-independent manner., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008237 metallopeptidase activity;GO:0031593 polyubiquitin modification-dependent protein binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0070552 BRISC complex;GO:0070531 BRCA1-A complex", "go_biological_process": "GO:0006508 proteolysis;GO:0006302 double-strand break repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q08CH3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08CL3-1", "uniprot_id": [ { "id": "KBTB8_DANRE", "url": "https://www.uniprot.org/uniprot/Q08CL3", "type": "external" } ], "mass": 68657.0, "length": 601, "protein_name": "Kelch repeat and BTB domain-containing protein 8", "gene_name": "kbtbd8", "organism": "Zebrafish", "refseq_name": "kelch repeat and BTB domain-containing protein 8", "refseq_ac": [ { "id": "NP_001103500", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103500", "type": "external" } ], "gene_names_uniprotkb": "kbtbd8; takrp; zgc:152950", "gene_names_refseq": "cb672; kbtbd8; takrp; wu:fc57a10; zgc:152950", "protein_names_uniprotkb": "Kelch repeat and BTB domain-containing protein 8; T-cell activation kelch repeat protein; TA-KRP", "protein_names_refseq": "T-cell activation kelch repeat protein; TA-KRP; kelch repeat and BTB domain-containing protein 8", "tax_id": 7955, "disease": "", "pathway": " (dre:559966); (R-DRE-8951664); (R-DRE-983168)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC154345.1, BC171518.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505377, SAMEA4476730 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC154345.1. On or before Apr 15, 2008 this sequence version replaced NP_001070034.1, XP_689697.1., [RefSeq]; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of neural crest specification (By similarity). The BCR(KBTBD8) complex acts by mediating monoubiquitination of target proteins (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8KC38", "ec_number_list": [], "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0005819 spindle;GO:0031463 Cul3-RING ubiquitin ligase complex", "go_biological_process": "GO:0014029 neural crest formation;GO:0006417 regulation of translation;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0014032 neural crest cell development;GO:0006513 protein monoubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q08CL3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0P3U3-1", "uniprot_id": [ { "id": "EXD1_DANRE", "url": "https://www.uniprot.org/uniprot/Q0P3U3", "type": "external" } ], "mass": 42794.0, "length": 378, "protein_name": "piRNA biogenesis protein EXD1", "gene_name": "exd1", "organism": "Zebrafish", "refseq_name": "piRNA biogenesis protein EXD1", "refseq_ac": [ { "id": "NP_001038930", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038930", "type": "external" } ], "gene_names_uniprotkb": "exd1; exdl1; zgc:154068", "gene_names_refseq": "exd1; zgc:154068", "protein_names_uniprotkb": "piRNA biogenesis protein EXD1; Exonuclease 3'-5' domain-containing protein 1; Exonuclease 3'-5' domain-like-containing protein 1; Inactive exonuclease EXD1", "protein_names_refseq": "exonuclease 3'-5' domain-containing protein 1; exonuclease 3'-5' domain-like-containing protein 1; inactive exonuclease EXD1; piRNA biogenesis protein EXD1", "tax_id": 7955, "disease": "", "pathway": " (dre:751755)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC122448.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505372, SAMEA3505373 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC122448.1., [RefSeq]; RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity. The PET complex is required during the secondary piRNAs metabolic process for the piwil2 slicing-triggered loading of piwil4 piRNAs. In the PET complex, exd1 probably acts as an RNA adapter. Exd1 is an inactive exonuclease., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:1990923 PET complex;GO:0043186 P granule", "go_biological_process": "GO:0031047 regulatory ncRNA-mediated gene silencing;GO:0034587 piRNA processing;GO:0051321 meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0P3U3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0P3X8-1", "uniprot_id": [ { "id": "LTOR4_DANRE", "url": "https://www.uniprot.org/uniprot/Q0P3X8", "type": "external" } ], "mass": 11101.0, "length": 99, "protein_name": "Ragulator complex protein LAMTOR4", "gene_name": "lamtor4", "organism": "Zebrafish", "refseq_name": "ragulator complex protein LAMTOR4", "refseq_ac": [ { "id": "NP_001038415", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038415", "type": "external" } ], "gene_names_uniprotkb": "lamtor4; fj17e01; si:dkey-159a18.7; wu:fj17e01; zgc:153714", "gene_names_refseq": "fj17e01; lamtor4; si:dkey-159a18.7; wu:fj17e01; zgc:153714", "protein_names_uniprotkb": "Ragulator complex protein LAMTOR4; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4", "protein_names_refseq": "UPF0539 protein C7orf59 homolog; late endosomal/lysosomal adaptor and MAPK and MTOR activator 4; ragulator complex protein LAMTOR4", "tax_id": 7955, "disease": "", "pathway": " (dre:561019); (R-DRE-1632852); (R-DRE-165159); (R-DRE-166208); (R-DRE-380972); (R-DRE-5628897); (R-DRE-8943724); (R-DRE-9639288)", "pathway_count": 8, "publication_count": 2, "publication_id_list": "23594743;40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC122392.1, EH434232.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC122392.1. On Sep 4, 2006 this sequence version replaced XP_689512.1., [RefSeq]; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator plays a dual role for the small GTPases Rag (RagA/RRAGA, RagB/RRAGB, RagC/RRAGC and/or RagD/RRAGD): it (1) acts as a guanine nucleotide exchange factor (GEF), activating the small GTPases Rag and (2) mediates recruitment of Rag GTPases to the lysosome membrane. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q5RGI9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005764 lysosome;GO:0005765 lysosomal membrane;GO:0071986 Ragulator complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0032008 positive regulation of TOR signaling;GO:0071230 cellular response to amino acid stimulus;GO:0061462 protein localization to lysosome;GO:0008361 regulation of cell size", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q0P3X8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0P3Z8-1", "uniprot_id": [ { "id": "UBX10_DANRE", "url": "https://www.uniprot.org/uniprot/Q0P3Z8", "type": "external" } ], "mass": 23939.0, "length": 214, "protein_name": "UBX domain-containing protein 10", "gene_name": "ubxn10", "organism": "Zebrafish", "refseq_name": "UBX domain-containing protein 10", "refseq_ac": [ { "id": "NP_001038911", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038911", "type": "external" } ], "gene_names_uniprotkb": "ubxn10; zgc:153648", "gene_names_refseq": "ubxn10; zgc:153648", "protein_names_uniprotkb": "UBX domain-containing protein 10", "protein_names_refseq": "UBX domain-containing protein 10", "tax_id": 7955, "disease": "", "pathway": " (dre:751736)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;26389662", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC122361.1, DN836773.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708828, SAMEA708836 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC122361.1., [RefSeq]; Required for ciliogenesis (PubMed:26389662). Acts as a tethering factor that facilitates recruitment of vcp/p97 to the intraflagellar transport complex B (IFT-B) in cilia (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005929 cilium", "go_biological_process": "GO:0060271 cilium assembly;GO:0036503 ERAD pathway;GO:0061371 determination of heart left/right asymmetry", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q0P3Z8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0P424-1", "uniprot_id": [ { "id": "ELP6_DANRE", "url": "https://www.uniprot.org/uniprot/Q0P424", "type": "external" } ], "mass": 29240.0, "length": 264, "protein_name": "Elongator complex protein 6", "gene_name": "elp6", "organism": "Zebrafish", "refseq_name": "elongator complex protein 6", "refseq_ac": [ { "id": "NP_001096612", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096612", "type": "external" } ], "gene_names_uniprotkb": "elp6; si:dkey-77n11.4; tmem103; zgc:153530", "gene_names_refseq": "elp6; si:dkey-77n11.4; tmem103; zgc:153530", "protein_names_uniprotkb": "Elongator complex protein 6; Protein TMEM103", "protein_names_refseq": "UPF0405 protein C3orf75 homolog; elongator complex protein 6 homolog; elongator complex protein 6; transmembrane protein 103", "tax_id": 7955, "disease": "", "pathway": " (dre:751679)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC152243.1, BC122319.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC152243.1. On or before Apr 23, 2008 this sequence version replaced NP_001038859.1, XP_001338726.1., [RefSeq]; Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (By similarity). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A7MCM9;A8DZD8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0033588 elongator holoenzyme complex", "go_biological_process": "GO:0030335 positive regulation of cell migration;GO:0002098 tRNA wobble uridine modification", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q0P424-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0P427-1", "uniprot_id": [ { "id": "PPR35_DANRE", "url": "https://www.uniprot.org/uniprot/Q0P427", "type": "external" } ], "mass": 28415.0, "length": 251, "protein_name": "Protein phosphatase 1 regulatory subunit 35", "gene_name": "ppp1r35", "organism": "Zebrafish", "refseq_name": "protein phosphatase 1 regulatory subunit 35", "refseq_ac": [ { "id": "NP_001038856", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038856", "type": "external" } ], "gene_names_uniprotkb": "ppp1r35; zgc:153512", "gene_names_refseq": "ppp1r35; zgc:153512", "protein_names_uniprotkb": "Protein phosphatase 1 regulatory subunit 35", "protein_names_refseq": "UPF0683 protein C7orf47 homolog; protein phosphatase 1 regulatory subunit 35", "tax_id": 7955, "disease": "", "pathway": " (dre:751676)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC122312.1, CK353624.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC122312.1., [RefSeq]; During centriole duplication, may play a role in the centriole elongation by promoting the recruitment of the microtubule-binding elongation machinery, leading to the centriole to centrosome conversion (By similarity). In addition may play a role in the primary cilia assembly (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004864 protein phosphatase inhibitor activity;GO:0019902 phosphatase binding", "go_cellular_component": "GO:0005813 centrosome;GO:0005814 centriole", "go_biological_process": "GO:0048570 notochord morphogenesis;GO:0045724 positive regulation of cilium assembly;GO:1903724 positive regulation of centriole elongation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0P427-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0P466-1", "uniprot_id": [ { "id": "TYW2_DANRE", "url": "https://www.uniprot.org/uniprot/Q0P466", "type": "external" } ], "mass": 45530.0, "length": 408, "protein_name": "tRNA wybutosine-synthesizing protein 2 homolog", "gene_name": "tyw2", "organism": "Zebrafish", "refseq_name": "tRNA wybutosine-synthesizing protein 2 homolog", "refseq_ac": [ { "id": "NP_001070632", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070632", "type": "external" } ], "gene_names_uniprotkb": "tyw2; trmt12; zgc:153361", "gene_names_refseq": "CH73-188I6.1; trmt12; tyw2; zgc:153361", "protein_names_uniprotkb": "tRNA wybutosine-synthesizing protein 2 homolog; 2.5.1.114; tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase; tRNA-yW-synthesizing protein 2", "protein_names_refseq": "alpha-amino-alpha-carboxypropyl transferase TYW2; homolog of yeast tRNA methyltransferase 12; tRNA methyltransferase 12 homolog; tRNA wybutosine-synthesizing protein 2 homolog; tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase; tRNA-yW-synthesizing protein 2", "tax_id": 7955, "disease": "", "pathway": " (dre:564925)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC122254.1, CN024882.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505376, SAMEA3505388 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC122254.1. On Oct 11, 2006 this sequence version replaced XP_693335.1., [RefSeq]; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.114", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.114", "type": "external" } ], "go_molecular_function": "GO:0008175 tRNA methyltransferase activity;GO:0102522 tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0030488 tRNA methylation;GO:0031591 wybutosine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0P466-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0P487-1", "uniprot_id": [ { "id": "NB5R2_DANRE", "url": "https://www.uniprot.org/uniprot/Q0P487", "type": "external" } ], "mass": 34388.0, "length": 309, "protein_name": "NADH-cytochrome b5 reductase 2", "gene_name": "cyb5r2", "organism": "Zebrafish", "refseq_name": "NADH-cytochrome b5 reductase 2", "refseq_ac": [ { "id": "NP_001038825", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038825", "type": "external" } ], "gene_names_uniprotkb": "cyb5r2; si:dkey-80c24.9; zgc:153291", "gene_names_refseq": "cyb5r2; im:7147295; zgc:153291", "protein_names_uniprotkb": "NADH-cytochrome b5 reductase 2; 1.6.2.2; b5R.2", "protein_names_refseq": "NADH-cytochrome b5 reductase 2; b5R.2", "tax_id": 7955, "disease": "methemoglobinemia (Disease Ontology:DOID:10783)", "pathway": " (dre:751641)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC122221.1, EH490615.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC122221.1., [RefSeq]; NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis and drug metabolism., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A2CET6", "ec_number_list": [ { "id": "1.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.2.2", "type": "external" } ], "go_molecular_function": "GO:0071949 FAD binding;GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H;GO:0090524 cytochrome-b5 reductase activity, acting on NADH", "go_cellular_component": "GO:0005739 mitochondrion;GO:0016020 membrane", "go_biological_process": "GO:0001878 response to yeast;GO:0016126 sterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q0P487-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0VFV6-1", "uniprot_id": [ { "id": "SELS_DANRE", "url": "https://www.uniprot.org/uniprot/Q0VFV6", "type": "external" } ], "mass": 21201.0, "length": 190, "protein_name": "Selenoprotein S", "gene_name": "vimp", "organism": "Zebrafish", "refseq_name": "selenoprotein S", "refseq_ac": [ { "id": "NP_001038799", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038799", "type": "external" } ], "gene_names_uniprotkb": "vimp; sels; zgc:136970", "gene_names_refseq": "selenos; sels; vimp; wu:fc16a03; zgc:136970", "protein_names_uniprotkb": "Selenoprotein S; SelS; VCP-interacting membrane protein", "protein_names_refseq": "VCP-interacting membrane protein; VCP-interacting membrane selenoprotein; selenoprotein S", "tax_id": 7955, "disease": "colorectal adenoma (Disease Ontology:DOID:0050860); colorectal carcinoma (Disease Ontology:DOID:0080199)", "pathway": " (dre:735249)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC118685.1, SRR26395039.1144926.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from JBMGRA010000007.1. On Feb 26, 2008 this sequence version replaced NP_001038799.1. This gene encodes a transmembrane protein that is localized in the endoplasmic reticulum (ER). It is involved in the degradation process of misfolded proteins in the ER, and may also have a role in inflammation control in higher eukaryotes. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs in vertebrates contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. [provided by RefSeq, Aug 2017]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0036502 Derlin-1-VIMP complex;GO:0036513 Derlin-1 retrotranslocation complex;GO:0005881 cytoplasmic microtubule", "go_biological_process": "GO:0030968 endoplasmic reticulum unfolded protein response;GO:0030970 retrograde protein transport, ER to cytosol", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q0VFV6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0VIL3-1", "uniprot_id": [ { "id": "OTOMP_DANRE", "url": "https://www.uniprot.org/uniprot/Q0VIL3", "type": "external" } ], "mass": 40776.0, "length": 371, "protein_name": "Otolith matrix protein 1", "gene_name": "otomp", "organism": "Zebrafish", "refseq_name": "otolith matrix protein 1 precursor", "refseq_ac": [ { "id": "NP_001038552", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038552", "type": "external" } ], "gene_names_uniprotkb": "otomp; omp1", "gene_names_refseq": "im:6904989; omp-1; omp; otomp; wu:fc44d11; zomp1", "protein_names_uniprotkb": "Otolith matrix protein 1; OMP-1", "protein_names_refseq": "otolith matrix protein 1 precursor; otolith matrix protein 1", "tax_id": 7955, "disease": "chromosome 3q29 microdeletion syndrome (Disease Ontology:DOID:0060419)", "pathway": " (dre:565818); (R-DRE-381426); (R-DRE-8957275)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15905077", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AY681353.1, BC134025.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY681353.1. On Sep 1, 2006 this sequence version replaced XP_694179.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Required for normal otolith growth and deposition of otolin-1 in the otolith., [UniProtKB, PubMed]; ZOMP-1 is required for normal otolith growth and deposition of zOtolin-1 in the otolith, and zOtolin-1 is involved in the correct arrangement of the otoliths onto the sensory epithelium of the inner ear and probably in stabilization of the otolith matrix, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6DGA2", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0055037 recycling endosome", "go_biological_process": "GO:0048840 otolith development;GO:0006826 iron ion transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q0VIL3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1JPT7-1", "uniprot_id": [ { "id": "THAP1_DANRE", "url": "https://www.uniprot.org/uniprot/Q1JPT7", "type": "external" } ], "mass": 25707.0, "length": 225, "protein_name": "THAP domain-containing protein 1", "gene_name": "thap1", "organism": "Zebrafish", "refseq_name": "THAP domain-containing protein 1", "refseq_ac": [ { "id": "NP_001410789", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410789", "type": "external" } ], "gene_names_uniprotkb": "thap1; zgc:136597", "gene_names_refseq": "thap1; zgc:136597", "protein_names_uniprotkb": "THAP domain-containing protein 1", "protein_names_refseq": "THAP domain-containing protein 1", "tax_id": 7955, "disease": "torsion dystonia 6 (Disease Ontology:DOID:0090039)", "pathway": " (dre:692315)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "26004199;26469318;31680844", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395017.1167308.1, SRR32588723.1761449.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505377, SAMEA4476739 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Jul 9, 2025 this sequence version replaced XP_073807130.1., [RefSeq]; DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0001935 endothelial cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q1JPT7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1JPX3-1", "uniprot_id": [ { "id": "SYFA_DANRE", "url": "https://www.uniprot.org/uniprot/Q1JPX3", "type": "external" } ], "mass": 56364.0, "length": 497, "protein_name": "Phenylalanine--tRNA ligase alpha subunit", "gene_name": "farsa", "organism": "Zebrafish", "refseq_name": "phenylalanine--tRNA ligase alpha subunit", "refseq_ac": [ { "id": "NP_001038760", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038760", "type": "external" } ], "gene_names_uniprotkb": "farsa; farsla; zgc:136506; zgc:158185", "gene_names_refseq": "farsa; farsla; wu:fj21a11; zgc:136506; zgc:158185", "protein_names_uniprotkb": "Phenylalanine--tRNA ligase alpha subunit; 6.1.1.20; PheRS; Phenylalanyl-tRNA synthetase alpha subunit", "protein_names_refseq": "pheRS; phenylalanine--tRNA ligase alpha chain; phenylalanine--tRNA ligase alpha subunit; phenylalanyl-tRNA synthetase alpha chain; phenylalanyl-tRNA synthetase, alpha subunit", "tax_id": 7955, "disease": "", "pathway": " (dre:692329)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC116564.1, BC066611.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC116564.1 and CK028671.1. On or before May 23, 2007 this sequence version replaced NP_001074965.1, NP_001038760.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6NYF9", "ec_number_list": [ { "id": "6.1.1.20", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.20", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0000049 tRNA binding;GO:0004826 phenylalanine-tRNA ligase activity", "go_cellular_component": "GO:0009328 phenylalanine-tRNA ligase complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0051290 protein heterotetramerization;GO:0006432 phenylalanyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q1JPX3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1L864-1", "uniprot_id": [ { "id": "JGN1B_DANRE", "url": "https://www.uniprot.org/uniprot/Q1L864", "type": "external" } ], "mass": 20750.0, "length": 183, "protein_name": "Protein jagunal homolog 1-B", "gene_name": "jagn1b", "organism": "Zebrafish", "refseq_name": "protein jagunal homolog 1-B", "refseq_ac": [ { "id": "NP_001003584", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003584", "type": "external" } ], "gene_names_uniprotkb": "jagn1b; si:ch73-162i18.3; zgc:101045", "gene_names_refseq": "jagn1b; wu:fb07b07; zgc:101045", "protein_names_uniprotkb": "Protein jagunal homolog 1-B", "protein_names_refseq": "protein jagunal homolog 1-B", "tax_id": 7955, "disease": "severe congenital neutropenia 6 (Disease Ontology:DOID:0112134)", "pathway": " (dre:445190)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;38739706", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH541043.1, BC078267.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476769 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH541043.1, JBMGRA010000022.1 and EH562191.1. On or before Jun 25, 2015 this sequence version replaced XP_009294716.1, NP_001003584.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the reference strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments., [RefSeq]; A JAGN1-associated severe congenital neutropenia zebrafish model revealed an altered G-CSFR signaling and UPR activation., [RefSeq, PubMed]; Endoplasmic reticulum transmembrane protein involved in vesicle-mediated transport, which is required for neutrophil function., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0030223 neutrophil differentiation;GO:0015031 protein transport;GO:0002446 neutrophil mediated immunity;GO:0016192 vesicle-mediated transport;GO:0050832 defense response to fungus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q1L864-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1L8A0-1", "uniprot_id": [ { "id": "Q1L8A0_DANRE", "url": "https://www.uniprot.org/uniprot/Q1L8A0", "type": "external" } ], "mass": 54708.0, "length": 482, "protein_name": "5'-3' exonuclease PLD3", "gene_name": "pld3", "organism": "Zebrafish", "refseq_name": "5'-3' exonuclease PLD3", "refseq_ac": [ { "id": "XP_003200538", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200538", "type": "external" } ], "gene_names_uniprotkb": "pld3", "gene_names_refseq": "pld3", "protein_names_uniprotkb": "5'-3' exonuclease PLD3; 3.1.16.1; Phospholipase D3", "protein_names_refseq": "5'-3' exonuclease PLD3", "tax_id": 7955, "disease": "spinocerebellar ataxia 46 (Disease Ontology:DOID:0080288)", "pathway": " (dre:571938)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RFK4", "ec_number_list": [], "go_molecular_function": "GO:0004527 exonuclease activity", "go_cellular_component": "GO:0012505 endomembrane system;GO:0031902 late endosome membrane;GO:0031901 early endosome membrane;GO:0043202 lysosomal lumen", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1L8A0-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1L8F9-1", "uniprot_id": [ { "id": "KICS2_DANRE", "url": "https://www.uniprot.org/uniprot/Q1L8F9", "type": "external" } ], "mass": 51167.0, "length": 449, "protein_name": "KICSTOR subunit 2", "gene_name": "kics2", "organism": "Zebrafish", "refseq_name": "KICSTOR subunit 2", "refseq_ac": [ { "id": "NP_001025261", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025261", "type": "external" } ], "gene_names_uniprotkb": "kics2; si:ch211-125a15.1; zgc:136251", "gene_names_refseq": "kics2; si:ch211-125a15.1; zgc:136251", "protein_names_uniprotkb": "KICSTOR subunit 2", "protein_names_refseq": "KICSTOR complex protein C12orf66 homolog; KICSTOR subunit 2; UPF0536 protein C12orf66 homolog", "tax_id": 7955, "disease": "autosomal recessive intellectual developmental disorder 83 (Disease Ontology:DOID:0061114)", "pathway": " (dre:555715); (R-DRE-9639288)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "23594743;39824192", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01035465.1, BC171357.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476811 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1 and BC171357.1. On or before Mar 25, 2009 this sequence version replaced NP_001038719.1, NP_001076454.1, NP_001025261.2., [RefSeq]; As part of the KICSTOR complex may function in the amino acid-sensing branch of the TORC1 signaling pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1JQ61;Q5RIG9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0140007 KICSTOR complex;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0042149 cellular response to glucose starvation;GO:0034198 cellular response to amino acid starvation;GO:1904262 negative regulation of TORC1 signaling;GO:0044782 cilium organization;GO:0061462 protein localization to lysosome", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q1L8F9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1L8G7-1", "uniprot_id": [ { "id": "GATD1_DANRE", "url": "https://www.uniprot.org/uniprot/Q1L8G7", "type": "external" } ], "mass": 26708.0, "length": 242, "protein_name": "GATA zinc finger domain-containing protein 1", "gene_name": "gatad1", "organism": "Zebrafish", "refseq_name": "GATA zinc finger domain-containing protein 1", "refseq_ac": [ { "id": "NP_001035454", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035454", "type": "external" } ], "gene_names_uniprotkb": "gatad1; im:7150682; si:dkey-231l1.7; zgc:136582", "gene_names_refseq": "gatad1; im:7150682; zgc:136582", "protein_names_uniprotkb": "GATA zinc finger domain-containing protein 1", "protein_names_refseq": "GATA zinc finger domain-containing protein 1", "tax_id": 7955, "disease": "dilated cardiomyopathy 2B (Disease Ontology:DOID:0110441)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC115186.1, BC078199.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC115186.1., [RefSeq]; Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q1RM13", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0031674 I band", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1L8G7-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1L8I0-1", "uniprot_id": [ { "id": "PUS7L_DANRE", "url": "https://www.uniprot.org/uniprot/Q1L8I0", "type": "external" } ], "mass": 73112.0, "length": 643, "protein_name": "Pseudouridylate synthase PUS7L", "gene_name": "pus7l", "organism": "Zebrafish", "refseq_name": "pseudouridylate synthase PUS7L", "refseq_ac": [ { "id": "NP_001038422", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038422", "type": "external" } ], "gene_names_uniprotkb": "pus7l; si:dkey-234l24.3", "gene_names_refseq": "pus7l; si:dkey-234l24.3", "protein_names_uniprotkb": "Pseudouridylate synthase PUS7L; 5.4.99.-; Pseudouridylate synthase 7 homolog-like protein", "protein_names_refseq": "pseudouridylate synthase 7 homolog-like protein; pseudouridylate synthase 7, like; pseudouridylate synthase PUS7L", "tax_id": 7955, "disease": "", "pathway": " (dre:561376)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC134851.1, SRR26395015.645779.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000004.1. On Sep 1, 2006 this sequence version replaced XP_689878.1., [RefSeq]; Pseudouridine synthase that catalyzes pseudouridylation of mRNAs., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4QN40", "ec_number_list": [ { "id": "5.4.99.12", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.99.12", "type": "external" }, { "id": "5.4.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.99.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0009982 pseudouridine synthase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006397 mRNA processing;GO:0001522 pseudouridine synthesis;GO:1990481 mRNA pseudouridine synthesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1L8I0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1L8Q4-1", "uniprot_id": [ { "id": "Q1L8Q4_DANRE", "url": "https://www.uniprot.org/uniprot/Q1L8Q4", "type": "external" } ], "mass": 59196.0, "length": 515, "protein_name": "Fatty acyl-CoA reductase", "gene_name": "si:dkey-97m3.1", "organism": "Zebrafish", "refseq_name": "fatty acyl-CoA reductase 1", "refseq_ac": [ { "id": "NP_001076558", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076558", "type": "external" } ], "gene_names_uniprotkb": "si:dkey-97m3.1", "gene_names_refseq": "si:dkey-97m3.1", "protein_names_uniprotkb": "Fatty acyl-CoA reductase; 1.2.1.84", "protein_names_refseq": "fatty acyl-CoA reductase 1", "tax_id": 7955, "disease": "dry eye syndrome (Disease Ontology:DOID:10140); alopecia (Disease Ontology:DOID:987)", "pathway": " (dre:100034578); (R-DRE-9640463)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "26469318;27189481;35295584", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.18435056.1, SRR32588719.8043770.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000004.1., [RefSeq]; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols., [UniProtKB, UniProtKB, UniProtKB]; Catalyzes the reduction of saturated and unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols. It plays an essential role in the production of ether lipids/plasmalogens which synthesis requires fatty alcohols. In parallel, it is also required for wax monoesters production since fatty alcohols also constitute a substrate for their synthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NCF7", "ec_number_list": [ { "id": "1.2.1.84", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.84", "type": "external" } ], "go_molecular_function": "GO:0080019 alcohol-forming very long-chain fatty acyl-CoA reductase activity;GO:0102965 alcohol-forming long-chain fatty acyl-CoA reductase activity", "go_cellular_component": "GO:0005777 peroxisome;GO:0005778 peroxisomal membrane", "go_biological_process": "GO:0008610 lipid biosynthetic process;GO:0035336 long-chain fatty-acyl-CoA metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q1L8Q4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1L8R9-1", "uniprot_id": [ { "id": "SNAPN_DANRE", "url": "https://www.uniprot.org/uniprot/Q1L8R9", "type": "external" } ], "mass": 14526.0, "length": 129, "protein_name": "SNARE-associated protein Snapin", "gene_name": "snapin", "organism": "Zebrafish", "refseq_name": "SNARE-associated protein Snapin", "refseq_ac": [ { "id": "NP_001038613", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038613", "type": "external" } ], "gene_names_uniprotkb": "snapin", "gene_names_refseq": "si:dkey-222b8.2; snapin", "protein_names_uniprotkb": "SNARE-associated protein Snapin; Biogenesis of lysosome-related organelles complex 1 subunit 7; SNAP-associated protein", "protein_names_refseq": "SNARE-associated protein Snapin", "tax_id": 7955, "disease": "Hermansky-Pudlak syndrome (Disease Ontology:DOID:3753)", "pathway": " (dre:567959)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;40930097", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588715.2241579.1, SRR32588731.3242431.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000019.1. On Sep 1, 2006 this sequence version replaced XP_696365.1., [RefSeq]; Required for normal biogenesis of lysosome-related organelles (LRO), and for targeting membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. Plays a role in intracellular vesicle trafficking, synaptic vesicle recycling, synaptic vesicle exocytosis, and lysosome movement and localization at the cell periphery through a mechanism that couples lysosomes to microtubule plus-end-directed kinesin motor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4VCF9", "ec_number_list": [], "go_molecular_function": "GO:0000149 SNARE binding", "go_cellular_component": "GO:0030141 secretory granule;GO:0030672 synaptic vesicle membrane;GO:0008021 synaptic vesicle;GO:0031083 BLOC-1 complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0010506 regulation of autophagy;GO:0007420 brain development;GO:0007040 lysosome organization;GO:0008333 endosome to lysosome transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q1L8R9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1L8T6-1", "uniprot_id": [ { "id": "Q1L8T6_DANRE", "url": "https://www.uniprot.org/uniprot/Q1L8T6", "type": "external" } ], "mass": 56282.0, "length": 571, "protein_name": "Pygopus homolog 2 isoform 1", "gene_name": "pygo2", "organism": "Zebrafish", "refseq_name": "pygopus homolog 2 isoform 1", "refseq_ac": [ { "id": "NP_001028283", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028283", "type": "external" } ], "gene_names_uniprotkb": "pygo2; wu:fc46c10; wu:fi37d10; wu:fj66f08; wu:fy30b05; zgc:111854", "gene_names_refseq": "pygo2; wu:fc46c10; wu:fi37d10; wu:fj66f08; wu:fy30b05; zgc:111854", "protein_names_uniprotkb": "Pygopus homolog 2 isoform 1", "protein_names_refseq": "pygopus homolog 2 isoform 1", "tax_id": 7955, "disease": "", "pathway": " (dre:613247); (R-DRE-201722)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "27189481;30366904", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01005560.1, GFIL01031957.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On Sep 22, 2008 this sequence version replaced NP_001028283.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Involved in signal transduction through the Wnt pathway., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N7S4", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0016055 Wnt signaling pathway;GO:0060828 regulation of canonical Wnt signaling pathway;GO:0048703 embryonic viscerocranium morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q1L8T6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1L8W0-1", "uniprot_id": [ { "id": "ZBT18_DANRE", "url": "https://www.uniprot.org/uniprot/Q1L8W0", "type": "external" } ], "mass": 59193.0, "length": 537, "protein_name": "Zinc finger and BTB domain-containing protein 18", "gene_name": "zbtb18", "organism": "Zebrafish", "refseq_name": "zinc finger and BTB domain-containing protein 18 isoform 1", "refseq_ac": [ { "id": "NP_001076421", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076421", "type": "external" } ], "gene_names_uniprotkb": "zbtb18; si:ch211-221n23.1; znf238", "gene_names_refseq": "si:ch211-221n23.1; zbtb18; znf238", "protein_names_uniprotkb": "Zinc finger and BTB domain-containing protein 18; Zinc finger protein 238", "protein_names_refseq": "BTB/POZ domain protein ZF238; novel zinc finger domain containing protein; zinc finger and BTB domain-containing protein 18 isoform 1; zinc finger and BTB domain-containing protein 18; zinc finger protein 238", "tax_id": 7955, "disease": "autosomal dominant intellectual developmental disorder (Disease Ontology:DOID:0060307); autosomal dominant intellectual developmental disorder 22 (Disease Ontology:DOID:0070052)", "pathway": " (dre:100003157)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "15520368;23594743;25556858;26107416;26469318;32094115;37752184", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01008517.1, SRR32588730.7916365.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On Aug 18, 2023 this sequence version replaced NP_001076421.1., [RefSeq]; Transcriptional repressor that plays a role in various developmental processes. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4JEX7", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q1L8W0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1L8X2-1", "uniprot_id": [ { "id": "ENSA_DANRE", "url": "https://www.uniprot.org/uniprot/Q1L8X2", "type": "external" } ], "mass": 13756.0, "length": 124, "protein_name": "Alpha-endosulfine", "gene_name": "ensa", "organism": "Zebrafish", "refseq_name": "alpha-endosulfine", "refseq_ac": [ { "id": "NP_001038649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038649", "type": "external" } ], "gene_names_uniprotkb": "ensa; si:dkey-24a7.3", "gene_names_refseq": "ensaa; ensa; si:dkeyp-24a7.3", "protein_names_uniprotkb": "Alpha-endosulfine", "protein_names_refseq": "alpha-endosulfine", "tax_id": 7955, "disease": "", "pathway": " (dre:569530)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA4476794, SAMN02418767 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000019.1. On Sep 1, 2006 this sequence version replaced XP_698017.1., [RefSeq]; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with ppp2r2d (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B3DHK3", "ec_number_list": [], "go_molecular_function": "GO:0019888 protein phosphatase regulator activity;GO:0051721 protein phosphatase 2A binding;GO:0019212 phosphatase inhibitor activity;GO:0004864 protein phosphatase inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0051301 cell division;GO:0000086 G2/M transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1L8X2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1L8Y6-1", "uniprot_id": [ { "id": "BBIP1_DANRE", "url": "https://www.uniprot.org/uniprot/Q1L8Y6", "type": "external" } ], "mass": 8291.0, "length": 72, "protein_name": "BBSome-interacting protein 1", "gene_name": "bbip1", "organism": "Zebrafish", "refseq_name": "BBSome-interacting protein 1", "refseq_ac": [ { "id": "NP_001159595", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001159595", "type": "external" } ], "gene_names_uniprotkb": "bbip1; bbip10; si:ch211-159c12.2; si:ch211-197i12.2", "gene_names_refseq": "bbip10; bbip1; si:ch211-197i12.2", "protein_names_uniprotkb": "BBSome-interacting protein 1; BBSome-interacting protein of 10 kDa", "protein_names_refseq": "BBSome interacting protein 10; BBSome-interacting protein 1; BBSome-interacting protein of 10 kDa", "tax_id": 7955, "disease": "Bardet-Biedl syndrome 18 (Disease Ontology:DOID:0110140)", "pathway": " (dre:795943); (R-DRE-5620922)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "19081074;23594743;24026985", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: CK363521.1, EH543562.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BX005362.6., [RefSeq]; BBIP10 links ciliogenesis, microtubule stability, and acetylation, [RefSeq, PubMed]; Required for primary cilia assembly., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0034464 BBSome", "go_biological_process": "GO:0060271 cilium assembly;GO:0070121 Kupffer's vesicle development;GO:0032402 melanosome transport;GO:0097500 receptor localization to non-motile cilium", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q1L8Y6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1L8Y7-1", "uniprot_id": [ { "id": "SHOC2_DANRE", "url": "https://www.uniprot.org/uniprot/Q1L8Y7", "type": "external" } ], "mass": 62696.0, "length": 561, "protein_name": "Leucine-rich repeat protein SHOC-2", "gene_name": "shoc2", "organism": "Zebrafish", "refseq_name": "leucine-rich repeat protein SHOC-2", "refseq_ac": [ { "id": "NP_001038251", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038251", "type": "external" } ], "gene_names_uniprotkb": "shoc2; si:ch211-159c12.3; si:ch211-197i12.3", "gene_names_refseq": "shoc2; si:ch211-159c12.3; si:ch211-197i12.3; zgc:152956", "protein_names_uniprotkb": "Leucine-rich repeat protein SHOC-2; Protein soc-2 homolog; Protein sur-8 homolog", "protein_names_refseq": "leucine-rich repeat protein SHOC-2; protein soc-2 homolog; protein sur-8 homolog; soc-2 suppressor of clear homolog", "tax_id": 7955, "disease": "RASopathy (Disease Ontology:DOID:0080690); Noonan syndrome-like disorder with loose anagen hair (Disease Ontology:DOID:0080691); Noonan syndrome-like disorder with loose anagen hair 1 (Disease Ontology:DOID:0080692); atopic dermatitis (Disease Ontology:DOID:3310)", "pathway": " (dre:555476); (R-DRE-5673000)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC155579.1, GFIL01035225.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505375, SAMEA3505391 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000022.1. On or before Sep 1, 2006 this sequence version replaced XP_682883.1, XP_706733.1., [RefSeq]; Core component of the SHOC2-MRAS-PP1c (SMP) holophosphatase complex that regulates activation of the MAPK pathway (By similarity). Acts as a scaffolding protein in the SMP complex (By similarity). The SMP complex specifically dephosphorylates the inhibitory phosphorylation Raf kinases, stimulating their kinase activities (By similarity). The SMP complex enhances the dephosphorylation activity and substrate specificity of PP1c (By similarity). May act as an inhibitor of keratinocyte differentiation (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0JMD9", "ec_number_list": [], "go_molecular_function": "GO:0019903 protein phosphatase binding", "go_cellular_component": "GO:0000164 protein phosphatase type 1 complex;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0046579 positive regulation of Ras protein signal transduction;GO:0035556 intracellular signal transduction;GO:0038180 nerve growth factor signaling pathway;GO:0140361 cyclic-GMP-AMP transmembrane import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1L8Y7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1L8Y9-1", "uniprot_id": [ { "id": "Q1L8Y9_DANRE", "url": "https://www.uniprot.org/uniprot/Q1L8Y9", "type": "external" } ], "mass": 64974.0, "length": 589, "protein_name": "Neuronal acetylcholine receptor subunit alpha-7", "gene_name": "chrna11", "organism": "Zebrafish", "refseq_name": "cholinergic receptor, nicotinic, alpha 11 precursor", "refseq_ac": [ { "id": "NP_001038562", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038562", "type": "external" } ], "gene_names_uniprotkb": "chrna11; si:ch211-39a7.1", "gene_names_refseq": "chrna11; si:ch211-39a7.1", "protein_names_uniprotkb": "Neuronal acetylcholine receptor subunit alpha-7; Nicotinic acetylcholine receptor subunit alpha-7", "protein_names_refseq": "cholinergic receptor, nicotinic, alpha 11 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:566141)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "26469318;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588729.23456080.1, SRR32588728.37934462.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000019.1. On Sep 1, 2006 this sequence version replaced XP_694504.1., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NAA0", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "1.5.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.2", "type": "external" } ], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential;GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity;GO:0005230 extracellular ligand-gated monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005892 acetylcholine-gated channel complex;GO:0045202 synapse;GO:0045211 postsynaptic membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0042391 regulation of membrane potential;GO:0007268 chemical synaptic transmission;GO:0034220 monoatomic ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q1L8Y9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1L981-1", "uniprot_id": [ { "id": "TDRD5_DANRE", "url": "https://www.uniprot.org/uniprot/Q1L981", "type": "external" } ], "mass": 101266.0, "length": 905, "protein_name": "Tudor domain-containing protein 5", "gene_name": "tdrd5", "organism": "Zebrafish", "refseq_name": "tudor domain-containing protein 5", "refseq_ac": [ { "id": "NP_001038315", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038315", "type": "external" } ], "gene_names_uniprotkb": "tdrd5; si:dkey-171o17.7", "gene_names_refseq": "si:dkey-171o17.7; tdrd5", "protein_names_uniprotkb": "Tudor domain-containing protein 5", "protein_names_refseq": "tudor domain-containing protein 5", "tax_id": 7955, "disease": "", "pathway": " (dre:557999)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588734.3822195.1, SRR26395050.888408.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898400, SAMN18715719 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000022.1. On Sep 1, 2006 this sequence version replaced XP_686255.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A4QN69", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0071546 pi-body;GO:0033391 chromatoid body;GO:0005737 cytoplasm", "go_biological_process": "GO:0030719 P granule organization;GO:0007286 spermatid development;GO:0141196 transposable element silencing by piRNA-mediated DNA methylation;GO:0007283 spermatogenesis;GO:0007281 germ cell development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1L981-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1L9A2-1", "uniprot_id": [ { "id": "OPA3_DANRE", "url": "https://www.uniprot.org/uniprot/Q1L9A2", "type": "external" } ], "mass": 17306.0, "length": 157, "protein_name": "Optic atrophy 3 protein homolog", "gene_name": "opa3", "organism": "Zebrafish", "refseq_name": "optic atrophy 3 protein homolog", "refseq_ac": [ { "id": "NP_001073635", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073635", "type": "external" } ], "gene_names_uniprotkb": "opa3; si:dkey-12o15.3", "gene_names_refseq": "opa3", "protein_names_uniprotkb": "Optic atrophy 3 protein homolog", "protein_names_refseq": "OPA3 outer mitochondrial membrane lipid metabolism regulator; optic atrophy 3 protein homolog", "tax_id": 7955, "disease": "3-methylglutaconic aciduria type 3 (Disease Ontology:DOID:0110004); optic atrophy 3 (Disease Ontology:DOID:0111433)", "pathway": " (dre:497278)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "20627962;23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC049503.1, BQ284120.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476755, SAMEA4476813 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000018.1., [RefSeq]; May play some role in mitochondrial processes., [UniProtKB]; Mitochondrial OPA3 is required to limit HMG-CoA-derived MGC and protect the electron transport chain against inhibitory compounds in a zebrafish model of Costeff Syndrome, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0007626 locomotory behavior;GO:0050881 musculoskeletal movement;GO:0019216 regulation of lipid metabolic process;GO:0031413 regulation of buoyancy", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q1L9A2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1L9G6-1", "uniprot_id": [ { "id": "Q1L9G6_DANRE", "url": "https://www.uniprot.org/uniprot/Q1L9G6", "type": "external" } ], "mass": 24974.0, "length": 231, "protein_name": "Tetraspanin", "gene_name": "cd9b", "organism": "Zebrafish", "refseq_name": "CD9 molecule b isoform X1", "refseq_ac": [ { "id": "XP_068075677", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068075677", "type": "external" } ], "gene_names_uniprotkb": "cd9b; cd9l; fb82b11; wu:fb82b11; zgc:56512", "gene_names_refseq": "cd9b; cd9l; fb82b11; wu:fb82b11; zgc:56512", "protein_names_uniprotkb": "Tetraspanin", "protein_names_refseq": "CD9 molecule b isoform X1", "tax_id": 7955, "disease": "urinary bladder cancer (Disease Ontology:DOID:11054); endometrial cancer (Disease Ontology:DOID:1380); ovarian cancer (Disease Ontology:DOID:2394); prostate adenocarcinoma (Disease Ontology:DOID:2526); transitional cell carcinoma (Disease Ontology:DOID:2671); cervix carcinoma (Disease Ontology:DOID:2893); severe acute respiratory syndrome (Disease Ontology:DOID:2945); breast carcinoma (Disease Ontology:DOID:3459)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BBY1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0007338 single fertilization;GO:0048916 posterior lateral line development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1L9G6-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LU93-1", "uniprot_id": [ { "id": "ABITM_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LU93", "type": "external" } ], "mass": 20504.0, "length": 177, "protein_name": "Protein Abitram", "gene_name": "abitram", "organism": "Zebrafish", "refseq_name": "protein Abitram", "refseq_ac": [ { "id": "NP_001038394", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038394", "type": "external" } ], "gene_names_uniprotkb": "abitram; fam206a; si:ch211-254e15.2; zgc:153072", "gene_names_refseq": "abitram; fam206a; si:ch211-254e15.2; zgc:153072", "protein_names_uniprotkb": "Protein Abitram; Actin-binding transcription modulator; Protein Simiate", "protein_names_refseq": "family with sequence similarity 206, member A; protein Abitram; protein FAM206A; protein Simiate", "tax_id": 7955, "disease": "", "pathway": " (dre:560419)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC125852.1, EH506393.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC125852.1. On Sep 1, 2006 this sequence version replaced XP_688912.1., [RefSeq]; May regulate actin polymerization, filopodia dynamics and arborization of neurons., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003785 actin monomer binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0030027 lamellipodium;GO:0030425 dendrite;GO:0030426 growth cone", "go_biological_process": "GO:0048813 dendrite morphogenesis;GO:0051489 regulation of filopodium assembly;GO:0030833 regulation of actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1LU93-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1Q9F3-1", "uniprot_id": [ { "id": "F1Q9F3_DANRE", "url": "https://www.uniprot.org/uniprot/F1Q9F3", "type": "external" } ], "mass": 100258.0, "length": 878, "protein_name": "Phosphatidylinositol 3-kinase catalytic subunit type 3", "gene_name": "pik3c3", "organism": "Zebrafish", "refseq_name": "phosphatidylinositol 3-kinase catalytic subunit type 3", "refseq_ac": [ { "id": "NP_001315462", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315462", "type": "external" } ], "gene_names_uniprotkb": "pik3c3; im:7147158; wu:fc13g06; wu:fz51e12; zgc:112016; zgc:113009", "gene_names_refseq": "im:7147158; pik3c3; wu:fc13g06; wu:fz51e12; zgc:112016; zgc:113009", "protein_names_uniprotkb": "Phosphatidylinositol 3-kinase catalytic subunit type 3; 2.7.1.137", "protein_names_refseq": "phosphatidylinositol 3-kinase catalytic subunit type 3; phosphoinositide-3-kinase, class 3", "tax_id": 7955, "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589)", "pathway": " (dre:548346)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "16109975;26469318;27189481;29980668;31539803;33329019;34746149", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01017378.1, GFIL01030375.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1, EH542626.1 and EH563762.1. On Jun 17, 2016 this sequence version replaced XP_005172338.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; These results not only reveal a role of PIK3C3 in gut homeostasis, but also provide a zebrafish inflammatory bowel disease model. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1P518", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0016303 1-phosphatidylinositol-3-kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005777 peroxisome;GO:0016020 membrane;GO:0030496 midbody", "go_biological_process": "GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process;GO:0000045 autophagosome assembly;GO:0006897 endocytosis;GO:0051301 cell division;GO:0048015 phosphatidylinositol-mediated signaling", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "F1Q9F3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6NK88-1", "uniprot_id": [ { "id": "F6NK88_DANRE", "url": "https://www.uniprot.org/uniprot/F6NK88", "type": "external" } ], "mass": 284649.0, "length": 2552, "protein_name": "Zinc finger FYVE domain-containing protein 26", "gene_name": "zfyve26", "organism": "Zebrafish", "refseq_name": "zinc finger FYVE domain-containing protein 26 isoform X1", "refseq_ac": [ { "id": "XP_003199781", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003199781", "type": "external" } ], "gene_names_uniprotkb": "zfyve26; wu:fc33a03", "gene_names_refseq": "wu:fc33a03; zfyve26", "protein_names_uniprotkb": "Zinc finger FYVE domain-containing protein 26", "protein_names_refseq": "zinc finger FYVE domain-containing protein 26 isoform X1", "tax_id": 7955, "disease": "hereditary spastic paraplegia 15 (Disease Ontology:DOID:0110768)", "pathway": " (dre:324565)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "16109975;22801083;24967841;26469318;26767746;39503232", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003199781.1. COMPLETENESS: full length., [RefSeq]; Phosphatidylinositol 3-phosphate-binding protein required for the abscission step in cytokinesis: recruited to the midbody during cytokinesis and acts as a regulator of abscission. May also be required for efficient homologous recombination DNA double-strand break repair., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1RSY3", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0032266 phosphatidylinositol-3-phosphate binding", "go_cellular_component": "", "go_biological_process": "GO:0007409 axonogenesis;GO:0007040 lysosome organization;GO:0000281 mitotic cytokinesis;GO:0000724 double-strand break repair via homologous recombination;GO:0048599 oocyte development", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F6NK88-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QZB5-1", "uniprot_id": [ { "id": "F1QZB5_DANRE", "url": "https://www.uniprot.org/uniprot/F1QZB5", "type": "external" } ], "mass": 51293.0, "length": 447, "protein_name": "Gamma-aminobutyric acid receptor subunit pi", "gene_name": "gabrz", "organism": "Zebrafish", "refseq_name": "gamma-aminobutyric acid type A receptor subunit zeta precursor", "refseq_ac": [ { "id": "NP_001108214", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108214", "type": "external" } ], "gene_names_uniprotkb": "gabrz; gabrp; zgc:171544", "gene_names_refseq": "gabrp; gabrz; zgc:171544", "protein_names_uniprotkb": "Gamma-aminobutyric acid receptor subunit pi; GABA(A) receptor subunit pi", "protein_names_refseq": "GABA-A receptor pi subunit; gamma-aminobutyric acid (GABA) A receptor, pi; gamma-aminobutyric acid (GABA) A receptor, zeta; gamma-aminobutyric acid type A receptor subunit zeta precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:561738)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "27189481;27453477;28252024;29702678;31934760;32339612;33737538", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01046074.1, SRR32588719.9899907.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476730, SAMEA4476731 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1. On or before Apr 21, 2018 this sequence version replaced XP_005156304.1, NP_001108214.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Pi subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA). GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit interfaces. When activated by GABA, GABAARs selectively allow the flow of chloride anions across the cell membrane down their electrochemical gradient. Pi-containing GABAARs are mostly located in peripheral tissues. In the uterus, pi subunits modulate uterus contraction by altering the sensitivity of GABAARs to pregnanolone. In the lungs, pi-containing GABAARs contribute to pulmonary fluid transport via luminal secretion of chloride., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B292", "ec_number_list": [ { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" } ], "go_molecular_function": "GO:0004890 GABA-A receptor activity;GO:0022851 GABA-gated chloride ion channel activity", "go_cellular_component": "GO:0016324 apical plasma membrane;GO:0034707 chloride channel complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "F1QZB5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6NUE7-1", "uniprot_id": [ { "id": "F6NUE7_DANRE", "url": "https://www.uniprot.org/uniprot/F6NUE7", "type": "external" } ], "mass": 34191.0, "length": 319, "protein_name": "Orthopedia homeobox a isoform X1", "gene_name": "otpa", "organism": "Zebrafish", "refseq_name": "orthopedia homeobox a isoform X1", "refseq_ac": [ { "id": "XP_005170306", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170306", "type": "external" } ], "gene_names_uniprotkb": "otpa", "gene_names_refseq": "otpa", "protein_names_uniprotkb": "Orthopedia homeobox a isoform X1", "protein_names_refseq": "orthopedia homeobox a isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BHN1", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0042552 myelination;GO:0007420 brain development;GO:0030182 neuron differentiation;GO:0035176 social behavior", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F6NUE7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QDY2-1", "uniprot_id": [ { "id": "F1QDY2_DANRE", "url": "https://www.uniprot.org/uniprot/F1QDY2", "type": "external" } ], "mass": 56517.0, "length": 506, "protein_name": "UTP--glucose-1-phosphate uridylyltransferase", "gene_name": "ugp2b", "organism": "Zebrafish", "refseq_name": "UDP-glucose pyrophosphorylase 2b isoform 2", "refseq_ac": [ { "id": "NP_997894", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997894", "type": "external" } ], "gene_names_uniprotkb": "ugp2b; Ugp2; fi53h10; wu:fi53h10; zgc:85662", "gene_names_refseq": "Ugp2; fi53h10; ugp2b; wu:fi53h10; zgc:85662", "protein_names_uniprotkb": "UTP--glucose-1-phosphate uridylyltransferase; 2.7.7.9", "protein_names_refseq": "UDP-glucose pyrophosphorylase 2b isoform 2; UDP-glucose pyrophosphorylase 2", "tax_id": 7955, "disease": "developmental and epileptic encephalopathy 83 (Disease Ontology:DOID:0112218); cancer (Disease Ontology:DOID:162)", "pathway": " (dre:334420)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "27189481;28252024;31820119;38803914;40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC067564.1, SRR32588725.3387353.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476736, SAMEA898399 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000017.1. On or before Nov 5, 2015 this sequence version replaced XP_005158554.1, NP_997894.1., [RefSeq]; UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1PLK9", "ec_number_list": [ { "id": "2.7.7.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.9", "type": "external" } ], "go_molecular_function": "GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0005978 glycogen biosynthetic process;GO:0006011 UDP-alpha-D-glucose metabolic process;GO:0008345 larval locomotory behavior;GO:0005977 glycogen metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "F1QDY2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1QJC0-1", "uniprot_id": [ { "id": "F1QJC0_DANRE", "url": "https://www.uniprot.org/uniprot/F1QJC0", "type": "external" } ], "mass": 20879.0, "length": 193, "protein_name": "Cysteine and glycine-rich protein 1", "gene_name": "csrp3", "organism": "Zebrafish", "refseq_name": "cysteine and glycine-rich protein 3 isoform 2", "refseq_ac": [ { "id": "NP_001006026", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006026", "type": "external" } ], "gene_names_uniprotkb": "csrp3; csrp3b; zgc:103468", "gene_names_refseq": "csrp3b; csrp3; zgc:103468", "protein_names_uniprotkb": "Cysteine and glycine-rich protein 1; Cysteine-rich protein 1", "protein_names_refseq": "Muscle LIM protein; cysteine and glycine-rich protein 3 isoform 2", "tax_id": 7955, "disease": "hypertrophic cardiomyopathy 12 (Disease Ontology:DOID:0110318); dilated cardiomyopathy 1M (Disease Ontology:DOID:0110449); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); dilated cardiomyopathy (Disease Ontology:DOID:12930); congestive heart failure (Disease Ontology:DOID:6000)", "pathway": " (dre:450005)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "18436206;18850331;19800866;19881492;24951566;29400650;30826063;34016526;38556571;39226992", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: CN177155.1, CO920244.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On or before Feb 11, 2016 this sequence version replaced XP_005168871.1, NP_001006026.1. Transcript Variant: This variant (2) lacks an exon in the 5' coding region which results in the use of a downstream start codon compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments, RNA-seq data and orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; A novel gene-trap line reveals the dynamic patterns and essential roles of cysteine and glycine-rich protein 3 in zebrafish heart development and regeneration. Erratum:[Cell Mol Life Sci. 2024 Sep 10;81(1):388. doi: 10.1007/s00018-024-05334-9. PMID: 39254683] Publication Status: Online-Only, [RefSeq, PubMed]; Could play a role in neuronal development., [UniProtKB, UniProtKB, UniProtKB]; Csrp3 is dispensable for sarcomere assembly during early muscle development. csrp3 is required for muscle mechanical stability under overloaded stress., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N2S2", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0008307 structural constituent of muscle;GO:0042805 actinin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0030018 Z disc", "go_biological_process": "GO:0060047 heart contraction;GO:0060048 cardiac muscle contraction;GO:0035994 response to muscle stretch;GO:0045214 sarcomere organization;GO:0060537 muscle tissue development", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "F1QJC0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6NMW9-1", "uniprot_id": [ { "id": "F6NMW9_DANRE", "url": "https://www.uniprot.org/uniprot/F6NMW9", "type": "external" } ], "mass": 189128.0, "length": 1685, "protein_name": "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha", "gene_name": "pik3c2a", "organism": "Zebrafish", "refseq_name": "phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha", "refseq_ac": [ { "id": "XP_021323497", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323497", "type": "external" } ], "gene_names_uniprotkb": "pik3c2a", "gene_names_refseq": "pik3c2a", "protein_names_uniprotkb": "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha; 2.7.1.137; 2.7.1.153; 2.7.1.154; Phosphoinositide 3-kinase-C2-alpha", "protein_names_refseq": "phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha", "tax_id": 7955, "disease": "cataract (Disease Ontology:DOID:83); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dre:571356)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M9P1D7;A0AC58HWT3;A0AC58HWU1", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0035091 phosphatidylinositol binding;GO:0016303 1-phosphatidylinositol-3-kinase activity;GO:0046934 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity;GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0030136 clathrin-coated vesicle", "go_biological_process": "GO:0001525 angiogenesis;GO:0006897 endocytosis;GO:0006887 exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F6NMW9-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q59I63-1", "uniprot_id": [ { "id": "AGRG1_DANRE", "url": "https://www.uniprot.org/uniprot/Q59I63", "type": "external" } ], "mass": 73124.0, "length": 648, "protein_name": "Adhesion G protein-coupled receptor G1", "gene_name": "adgrg1", "organism": "Zebrafish", "refseq_name": "adhesion G-protein coupled receptor G1 precursor", "refseq_ac": [ { "id": "NP_001018317", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018317", "type": "external" } ], "gene_names_uniprotkb": "adgrg1; fc49b10; gpr56; si:dkey-181f22.4; wu:fc49b10", "gene_names_refseq": "adgrg1; fc49b10; gpr56; wu:fc49b10", "protein_names_uniprotkb": "Adhesion G protein-coupled receptor G1; ADGRG1 C-terminal fragment; ADGRG1 CT; ADGRG1 N-terminal fragment; ADGRG1 NT; G protein-coupled receptor 56", "protein_names_refseq": "G protein-coupled receptor 56; adhesion G-protein coupled receptor G1 precursor", "tax_id": 7955, "disease": "complex cortical dysplasia with other brain malformations 14A (Disease Ontology:DOID:0080922); complex cortical dysplasia with other brain malformations 14B (Disease Ontology:DOID:0080924)", "pathway": " (dre:101882156)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15753045;23594743;25607772;29367382;37175447", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AB193557.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB193557.1., [RefSeq]; Adhesion G protein-coupled receptor (aGPCR), which is involved in oligodendrocyte development and maintenance of peripheral myelin (PubMed:25607772, PubMed:29367382). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as RhoA pathway (PubMed:25607772). Adgrg1 is coupled to G(12) and/or G(13) G proteins (gna12 and gna13, respectively) and mediates the activation Rho small GTPases (PubMed:25607772, PubMed:29367382). Adgrg1-dependent RhoA signaling promotes timely radial sorting of axons (PubMed:29367382). Required to establish proper myelin thickness and facilitate organization of the myelin sheath in the mature peripheral nervous system (PubMed:29367382)., [UniProtKB, PubMed, PubMed]; Gpr56 as a new regulator in the development and maintenance of peripheral myelin., [RefSeq, PubMed]; Gpr56 regulates oligodendrocyte development via interactions with Galpha12/13 and RhoA Publication Status: Online-Only, [RefSeq, PubMed]; Transcriptomics and Phenotypic Analysis of gpr56 Knockout in Zebrafish. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "A0A0R4IXA8;A0A8M2BDY6;F1QZM9", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004672 protein kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0032287 peripheral nervous system myelin maintenance;GO:0036269 swimming behavior;GO:0014003 oligodendrocyte development;GO:0070445 regulation of oligodendrocyte progenitor proliferation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q59I63-1", "record_type": "protein", "filter_code": "0000000.0100111.100000.000000000000000001.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q567V6-1", "uniprot_id": [ { "id": "EIF3K_DANRE", "url": "https://www.uniprot.org/uniprot/Q567V6", "type": "external" } ], "mass": 25427.0, "length": 219, "protein_name": "Eukaryotic translation initiation factor 3 subunit K", "gene_name": "eif3k", "organism": "Zebrafish", "refseq_name": "eukaryotic translation initiation factor 3 subunit K", "refseq_ac": [ { "id": "NP_001017583", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017583", "type": "external" } ], "gene_names_uniprotkb": "eif3k; EIF3K; EIF3S12; eif3s12; zgc:110726", "gene_names_refseq": "eif3k; zgc:110726", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit K; Eukaryotic translation initiation factor 3 subunit 12; eIF-3 p25; eIF3k", "protein_names_refseq": "eukaryotic translation initiation factor 3 subunit K", "tax_id": 7955, "disease": "", "pathway": " (dre:550245); (R-DRE-156827); (R-DRE-72649); (R-DRE-72689); (R-DRE-72695); (R-DRE-72702)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "40044042", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC093002.1, CT656678.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505382, SAMEA4476735 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC093002.1., [RefSeq]; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation., [UniProtKB, HAMAP, UniProtKB]; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0043022 ribosome binding;GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0005852 eukaryotic translation initiation factor 3 complex", "go_biological_process": "GO:0006413 translational initiation;GO:0006446 regulation of translational initiation;GO:0001732 formation of cytoplasmic translation initiation complex", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q567V6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q4QRK0-1", "uniprot_id": [ { "id": "MAP11_DANRE", "url": "https://www.uniprot.org/uniprot/Q4QRK0", "type": "external" } ], "mass": 43567.0, "length": 386, "protein_name": "Methionine aminopeptidase 1", "gene_name": "metap1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "metap1; fc84e12; im:7047238; wu:fc84e12; zgc:110093", "gene_names_refseq": "", "protein_names_uniprotkb": "Methionine aminopeptidase 1; 3.4.11.18; MAP 1; MetAP 1; Peptidase M 1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:503783); (R-DRE-2514859)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "16109975;18976794;21937698;22182705;24198278;29914980;33264657;35584702;38138044;40044042", "class_list": "", "function": "Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)., [UniProtKB, UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6DHD3", "ec_number_list": [ { "id": "3.4.11.18", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.11.18", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0070006 metalloaminopeptidase activity;GO:0004239 initiator methionyl aminopeptidase activity;GO:0004177 aminopeptidase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0016485 protein processing;GO:0006882 intracellular zinc ion homeostasis;GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q4QRK0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LYS1-1", "uniprot_id": [ { "id": "Q1LYS1_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LYS1", "type": "external" } ], "mass": 87692.0, "length": 768, "protein_name": "Semaphorin-3E precursor", "gene_name": "sema3e", "organism": "Zebrafish", "refseq_name": "semaphorin-3E precursor", "refseq_ac": [ { "id": "NP_001038549", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038549", "type": "external" } ], "gene_names_uniprotkb": "sema3e; fj37c11; si:ch211-120m13.2; wu:fj37c11", "gene_names_refseq": "fj37c11; sema3e; si:ch211-120m13.2; wu:fj37c11", "protein_names_uniprotkb": "Semaphorin-3E precursor", "protein_names_refseq": "semaphorin 3E; semaphorin-3E precursor", "tax_id": 7955, "disease": "CHARGE syndrome (Disease Ontology:DOID:0050834)", "pathway": " (dre:565658); (R-DRE-416700)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "17879313;19422817;23825413;26732841;27189481;30661757;31349972;31464029;35431796;38628398", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01021259.1, SRR32588727.91469.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476731, SAMEA4476744 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000018.1. On Sep 1, 2006 this sequence version replaced XP_694017.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Semaphorin sema3E is involved in the pathogenesis of CHARGE syndrome by modulating cranial neural crest cell migration, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1N9X0", "ec_number_list": [], "go_molecular_function": "GO:0030215 semaphorin receptor binding;GO:0038191 neuropilin binding;GO:0045499 chemorepellent activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0001755 neural crest cell migration;GO:0002040 sprouting angiogenesis;GO:0007411 axon guidance;GO:2000289 regulation of photoreceptor cell axon guidance;GO:0030335 positive regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q1LYS1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8M9PIC1-1", "uniprot_id": [ { "id": "A0A8M9PIC1_DANRE", "url": "https://www.uniprot.org/uniprot/A0A8M9PIC1", "type": "external" } ], "mass": 88533.0, "length": 782, "protein_name": "Angiogenic factor with G patch and FHA domains 1 isoform X1", "gene_name": "aggf1", "organism": "Zebrafish", "refseq_name": "angiogenic factor with G patch and FHA domains 1 isoform X1", "refseq_ac": [ { "id": "XP_021324539", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324539", "type": "external" } ], "gene_names_uniprotkb": "aggf1; im:7146636; zgc:152959", "gene_names_refseq": "aggf1; im:7146636; zgc:152959", "protein_names_uniprotkb": "Angiogenic factor with G patch and FHA domains 1 isoform X1", "protein_names_refseq": "angiogenic factor with G patch and FHA domains 1 isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003676 nucleic acid binding", "go_cellular_component": "", "go_biological_process": "GO:0060217 hemangioblast cell differentiation;GO:0001525 angiogenesis;GO:0001570 vasculogenesis;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0048514 blood vessel morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A8M9PIC1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LWQ2-1", "uniprot_id": [ { "id": "Q1LWQ2_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LWQ2", "type": "external" } ], "mass": 39750.0, "length": 346, "protein_name": "Negative elongation factor E", "gene_name": "nelfe", "organism": "Zebrafish", "refseq_name": "negative elongation factor E isoform X1", "refseq_ac": [ { "id": "XP_005170084", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170084", "type": "external" } ], "gene_names_uniprotkb": "nelfe; rdbp; zgc:92496", "gene_names_refseq": "nelfe; rdbp; zgc:92496", "protein_names_uniprotkb": "Negative elongation factor E; RNA-binding protein RD", "protein_names_refseq": "negative elongation factor E isoform X1", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. Provides the strongest RNA binding activity of the NELF complex and may initially recruit the NELF complex to RNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2BHS3", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003746 translation elongation factor activity", "go_cellular_component": "GO:0005694 chromosome;GO:0032021 NELF complex", "go_biological_process": "GO:0030852 regulation of granulocyte differentiation;GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:1901534 positive regulation of hematopoietic progenitor cell differentiation;GO:1902038 positive regulation of hematopoietic stem cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LWQ2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q566Y1-1", "uniprot_id": [ { "id": "ELP4_DANRE", "url": "https://www.uniprot.org/uniprot/Q566Y1", "type": "external" } ], "mass": 43752.0, "length": 397, "protein_name": "Elongator complex protein 4", "gene_name": "elp4", "organism": "Zebrafish", "refseq_name": "elongator complex protein 4", "refseq_ac": [ { "id": "NP_001017638", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017638", "type": "external" } ], "gene_names_uniprotkb": "elp4; fi38c09; si:dkey-157g7.1; wu:fi38c09; zgc:112389", "gene_names_refseq": "elp4; fi38c09; wu:fi38c09; zgc:112389", "protein_names_uniprotkb": "Elongator complex protein 4; ELP4", "protein_names_refseq": "elongation protein 4 homolog; elongator complex protein 4", "tax_id": 7955, "disease": "aniridia (Disease Ontology:DOID:12271)", "pathway": " (dre:550331)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC093280.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC093280.1., [RefSeq]; Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A2BDL9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0008023 transcription elongation factor complex;GO:0033588 elongator holoenzyme complex;GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0002098 tRNA wobble uridine modification", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q566Y1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q3B7Q7-1", "uniprot_id": [ { "id": "NUBP2_DANRE", "url": "https://www.uniprot.org/uniprot/Q3B7Q7", "type": "external" } ], "mass": 28618.0, "length": 268, "protein_name": "Cytosolic Fe-S cluster assembly factor nubp2", "gene_name": "nubp2", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "nubp2; NUBP2; zgc:123336", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytosolic Fe-S cluster assembly factor nubp2; NBP 2; Nucleotide-binding protein 2", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:641290)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "26469318", "class_list": "", "function": "Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The nubp1-nubp2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0051536 iron-sulfur cluster binding;GO:0140663 ATP-dependent FeS chaperone activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005814 centriole;GO:0005930 axoneme", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3B7Q7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q566V3-1", "uniprot_id": [ { "id": "MRM3A_DANRE", "url": "https://www.uniprot.org/uniprot/Q566V3", "type": "external" } ], "mass": 48590.0, "length": 435, "protein_name": "rRNA methyltransferase 3A, mitochondrial", "gene_name": "mrm3a", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "mrm3a; rnmtl1a; rnmtl1; zgc:112452", "gene_names_refseq": "", "protein_names_uniprotkb": "rRNA methyltransferase 3A, mitochondrial; 2.1.1.-; RNA methyltransferase-like protein 1A; rRNA (guanosine-2'-O)-methyltransferase", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:550390)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "16109975;25009282;27357367", "class_list": "", "function": "S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1485 (Gm1485) in the mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA. Also required for formation of 2'-O-methyluridine at position 1484 (Um1484) mediated by MRM2., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0008650 rRNA (uridine-2'-O-)-methyltransferase activity;GO:0008173 RNA methyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005737 cytoplasm", "go_biological_process": "GO:0006364 rRNA processing;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q566V3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LWV4-1", "uniprot_id": [ { "id": "LHX9_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LWV4", "type": "external" } ], "mass": 44020.0, "length": 396, "protein_name": "LIM/homeobox protein Lhx9", "gene_name": "lhx9", "organism": "Zebrafish", "refseq_name": "LIM/homeobox protein Lhx9 isoform 2", "refseq_ac": [ { "id": "NP_001032320", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032320", "type": "external" } ], "gene_names_uniprotkb": "lhx9; si:dkey-121a9.2; zgc:112196", "gene_names_refseq": "lhx9; si:dkey-121a9.2; zgc:112196", "protein_names_uniprotkb": "LIM/homeobox protein Lhx9; LIM homeobox protein 9", "protein_names_refseq": "LIM homeodomain type transcription factor Lhx9; LIM/homeobox protein Lhx9 isoform 2; LIM/homeobox protein Lhx9", "tax_id": 7955, "disease": "depressive disorder (Disease Ontology:DOID:1596)", "pathway": " (dre:550405)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "16226737;17279576;19369545;19553285;21226904;23594743;33357384;33579692;35356436;35588359;39122556", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AB188254.1, GFIL01014457.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505375 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH447961.1, BC163023.1 and JBMGRA010000022.1. On Sep 5, 2015 this sequence version replaced NP_001032320.1. Transcript Variant: This variant (2) represents the longer transcript and encodes the longer isoform (2). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; May be involved in gonadal development., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3LHM3", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription;GO:0030182 neuron differentiation;GO:0048665 neuron fate specification;GO:0021794 thalamus development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q1LWV4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q567W6-1", "uniprot_id": [ { "id": "DPH1_DANRE", "url": "https://www.uniprot.org/uniprot/Q567W6", "type": "external" } ], "mass": 42770.0, "length": 381, "protein_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 1", "gene_name": "dph1", "organism": "Zebrafish", "refseq_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 1", "refseq_ac": [ { "id": "NP_001017861", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017861", "type": "external" } ], "gene_names_uniprotkb": "dph1; zgc:110702", "gene_names_refseq": "dph1; zgc:110702", "protein_names_uniprotkb": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; 2.5.1.108; Diphthamide biosynthesis protein 1; Diphtheria toxin resistance protein 1; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1", "protein_names_refseq": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1; diphthamide biosynthesis protein 1; diphtheria toxin resistance protein 1", "tax_id": 7955, "disease": "Miller-Dieker lissencephaly syndrome (Disease Ontology:DOID:0060469); diphthamide deficiency syndrome (Disease Ontology:DOID:0070476); diphthamide deficiency syndrome 1 (Disease Ontology:DOID:0070477)", "pathway": " (dre:550559); (R-DRE-5358493)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC092989.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC092989.1. On Jul 6, 2005 this sequence version replaced XP_701803.1., [RefSeq]; Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2 (By similarity). Dph1 and dph2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising dph3 and a NADH-dependent reductase (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.108", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.108", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0090560 2-(3-amino-3-carboxypropyl)histidine synthase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0120513 2-(3-amino-3-carboxypropyl)histidine synthase complex", "go_biological_process": "GO:0017183 protein histidyl modification to diphthamide", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q567W6-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q2TLY1-1", "uniprot_id": [ { "id": "MACO2_DANRE", "url": "https://www.uniprot.org/uniprot/Q2TLY1", "type": "external" } ], "mass": 78344.0, "length": 699, "protein_name": "Macoilin-2", "gene_name": "maco1b", "organism": "Zebrafish", "refseq_name": "macoilin-2 isoform 1", "refseq_ac": [ { "id": "NP_956757", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956757", "type": "external" } ], "gene_names_uniprotkb": "maco1b; si:dkey-9g4.5; tmem57b; zgc:63610", "gene_names_refseq": "maco1b; tmem57b; zgc:63610", "protein_names_uniprotkb": "Macoilin-2; Transmembrane protein 57b", "protein_names_refseq": "macoilin-2 isoform 1; transmembrane protein 57b", "tax_id": 7955, "disease": "", "pathway": " (dre:393435)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395039.137029.1, SRR26395012.647367.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On or before Jul 29, 2025 this sequence version replaced XP_005157105.1, NP_956757.2., [RefSeq]; May play a role in the regulation of neuronal activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "B7ZUY4", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0030424 axon;GO:0031965 nuclear membrane;GO:0030867 rough endoplasmic reticulum membrane", "go_biological_process": "GO:0023041 neuronal signal transduction;GO:0006935 chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2TLY1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LYE3-1", "uniprot_id": [ { "id": "Z143B_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LYE3", "type": "external" } ], "mass": 67929.0, "length": 623, "protein_name": "Zinc finger protein 143B", "gene_name": "znf143b", "organism": "Zebrafish", "refseq_name": "zinc finger protein 143B isoform 1", "refseq_ac": [ { "id": "NP_001428962", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428962", "type": "external" } ], "gene_names_uniprotkb": "znf143b; Zfp143; si:dkey-8l13.2; staf; zgc:66276; znf143", "gene_names_refseq": "Zfp143; zgc:66276; znf143b; znf143", "protein_names_uniprotkb": "Zinc finger protein 143B; Selenocysteine tRNA gene transcription-activating factor", "protein_names_refseq": "selenocysteine tRNA activating factor; selenocysteine tRNA gene transcription-activating factor; staf; zinc finger protein 143B isoform 1; zinc finger protein 143", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 4, "publication_id_list": "15087134;22268977;23594743;31969120", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC124735.1, SRR32588734.2992498.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505377 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1. On Jul 21, 2025 this sequence version replaced XP_009291820.1., [RefSeq]; The knockdown of the transcriptional activator ZNF143 by injection of translational-blocking Morpholino Oligonucleotides causes many significant phenotypic effects in zebrafish embryos Publication Status: Online-Only, [RefSeq, PubMed]; Transcription factor that activates expression of genes transcribed by both RNA polymerases II and III, and which is required to safeguard mitochondrial activity. Specifically recognizes and binds the Staf-binding site (SBS), a consensus DNA-binding motif present in thousands of promoters. Activates the gene for selenocysteine tRNA (tRNAsec). Activates expression of small nuclear RNA (snRNA) transcribed by RNA polymerases II and III. Also activates expression of mRNAs and acts as a key regulator of cell proliferation and differentiation by specifically activating expression of a subset of nuclear-encoded mitochondrial genes, thereby controlling mitochondrial function., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Two paralogous znf143 genes in zebrafish encode transcriptional activator proteins with similar functions but expressed at different levels during early development. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AUQ7;Q6VQB1", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007420 brain development;GO:0045893 positive regulation of DNA-templated transcription;GO:0061035 regulation of cartilage development", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q1LYE3-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LXZ9-1", "uniprot_id": [ { "id": "SKR1B_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LXZ9", "type": "external" } ], "mass": 84682.0, "length": 751, "protein_name": "SKI family transcriptional corepressor 1 homolog-B", "gene_name": "skor1b", "organism": "Zebrafish", "refseq_name": "SKI family transcriptional corepressor 1 homolog-B", "refseq_ac": [ { "id": "NP_001038598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038598", "type": "external" } ], "gene_names_uniprotkb": "skor1b; lbxcor1; si:dkey-246a16.3; skor1", "gene_names_refseq": "lbxcor1; si:dkey-246a16.3; skor1b; skor1", "protein_names_uniprotkb": "SKI family transcriptional corepressor 1 homolog-B; Ladybird homeobox corepressor 1 homolog-B", "protein_names_refseq": "SKI family transcriptional corepressor 1 homolog-B; SKI family transcriptional corepressor 1 homolog; ladybird homeobox corepressor 1 homolog-B; ladybird homeobox corepressor 1 homolog", "tax_id": 7955, "disease": "nervous system disease (Disease Ontology:DOID:863)", "pathway": " (dre:567457)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;38456494", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: LC760471.1, SRR32588730.14254125.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000018.1. On Sep 1, 2006 this sequence version replaced XP_695846.1., [RefSeq]; Foxp and Skor family proteins control differentiation of Purkinje cells from Ptf1a- and Neurog1-expressing progenitors in zebrafish., [RefSeq, PubMed]; May inhibit BMP signaling., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4IFZ1", "ec_number_list": [], "go_molecular_function": "GO:0046332 SMAD binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0030514 negative regulation of BMP signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q1LXZ9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q2THW0-1", "uniprot_id": [ { "id": "DHC5A_DANRE", "url": "https://www.uniprot.org/uniprot/Q2THW0", "type": "external" } ], "mass": 80501.0, "length": 744, "protein_name": "Palmitoyltransferase ZDHHC5-A", "gene_name": "zdhhc5a", "organism": "Zebrafish", "refseq_name": "palmitoyltransferase ZDHHC5-A", "refseq_ac": [ { "id": "NP_001034729", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034729", "type": "external" } ], "gene_names_uniprotkb": "zdhhc5a; DHHC-5A; si:dkey-28b4.5", "gene_names_refseq": "DHHC-5A; si:dkey-28b4.5; zdhhc5a", "protein_names_uniprotkb": "Palmitoyltransferase ZDHHC5-A; 2.3.1.225; DHHC-5A; Zinc finger DHHC domain-containing protein 5-A", "protein_names_refseq": "membrane-associated DHHC5 zinc finger protein; palmitoyltransferase ZDHHC5-A; palmitoyltransferase ZDHHC5a; zinc finger DHHC domain-containing protein 5-A; zinc finger DHHC-type containing 5a; zinc finger DHHC-type palmitoyltransferase 5a", "tax_id": 7955, "disease": "", "pathway": " (dre:571795)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23594743;27235108", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AY871210.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505376, SAMEA3505388 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY871210.1. On Mar 1, 2006 this sequence version replaced XP_700515.1., [RefSeq]; Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and is involved in a variety of cellular processes., [UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.225", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.225", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" } ], "go_molecular_function": "GO:0019706 protein-cysteine S-palmitoyltransferase activity;GO:0016409 palmitoyltransferase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0062208 positive regulation of pattern recognition receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q2THW0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q502P7-1", "uniprot_id": [ { "id": "BANP_DANRE", "url": "https://www.uniprot.org/uniprot/Q502P7", "type": "external" } ], "mass": 55463.0, "length": 508, "protein_name": "Protein BANP", "gene_name": "banp", "organism": "Zebrafish", "refseq_name": "protein BANP", "refseq_ac": [ { "id": "NP_001018468", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018468", "type": "external" } ], "gene_names_uniprotkb": "banp; zgc:111954", "gene_names_refseq": "banp; zgc:111954", "protein_names_uniprotkb": "Protein BANP", "protein_names_refseq": "protein BANP", "tax_id": 7955, "disease": "", "pathway": " (R-DRE-6804759); (R-DRE-9766229)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC095613.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505375 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC095613.1., [RefSeq]; DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 activation, which causes cell cycle arrest (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006325 chromatin organization;GO:0010564 regulation of cell cycle process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q502P7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q502L1-1", "uniprot_id": [ { "id": "ACB5A_DANRE", "url": "https://www.uniprot.org/uniprot/Q502L1", "type": "external" } ], "mass": 55489.0, "length": 501, "protein_name": "Acyl-CoA-binding domain-containing protein 5A", "gene_name": "acbd5a", "organism": "Zebrafish", "refseq_name": "acyl-CoA-binding domain-containing protein 5A", "refseq_ac": [ { "id": "NP_001018483", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018483", "type": "external" } ], "gene_names_uniprotkb": "acbd5a; acbd5; zgc:112043", "gene_names_refseq": "acbd5a; zgc:112043", "protein_names_uniprotkb": "Acyl-CoA-binding domain-containing protein 5A", "protein_names_refseq": "acyl-CoA-binding domain-containing protein 5A; acyl-Coenzyme A binding domain containing 5a", "tax_id": 7955, "disease": "retinal dystrophy with leukodystrophy (Disease Ontology:DOID:0080946); peroxisomal disease (Disease Ontology:DOID:906)", "pathway": " (dre:553674); (R-DRE-390918); (R-DRE-8980692); (R-DRE-9013106); (R-DRE-9603798)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC095655.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC095655.1., [RefSeq]; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000062 fatty-acyl-CoA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005777 peroxisome;GO:0016020 membrane", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0000425 pexophagy", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q502L1-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q502M5-1", "uniprot_id": [ { "id": "EDC3_DANRE", "url": "https://www.uniprot.org/uniprot/Q502M5", "type": "external" } ], "mass": 54852.0, "length": 507, "protein_name": "Enhancer of mRNA-decapping protein 3", "gene_name": "edc3", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "edc3; im:7151288; lsm16; wu:fb82d07; yjdc; zgc:112006", "gene_names_refseq": "", "protein_names_uniprotkb": "Enhancer of mRNA-decapping protein 3; LSM16 protein homolog; YjeF domain-containing protein 1", "protein_names_refseq": "", "tax_id": 7955, "disease": "autosomal recessive intellectual developmental disorder 50 (Disease Ontology:DOID:0081213)", "pathway": " (dre:504054); (R-DRE-430039)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "16109975;18307296;19240133;26469318;27189481;40044042", "class_list": "", "function": "Binds single-stranded RNA. Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0000932 P-body", "go_biological_process": "GO:0033962 P-body assembly;GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q502M5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LVW0-1", "uniprot_id": [ { "id": "ABT3A_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LVW0", "type": "external" } ], "mass": 113811.0, "length": 1021, "protein_name": "Ankyrin repeat- and BTB/POZ domain-containing protein 3-A", "gene_name": "abtb3a; btbd11a", "organism": "Zebrafish", "refseq_name": "ankyrin repeat- and BTB/POZ domain-containing protein 3-A isoform 2", "refseq_ac": [ { "id": "NP_001038467", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038467", "type": "external" } ], "gene_names_uniprotkb": "abtb3a; btbd11a; abtb3a; btbd11a; btbd11; si:ch211-133h2.1; si:ch211-161f1.1", "gene_names_refseq": "abtb3a; btbd11a; btbd11; si:ch211-161f1.1", "protein_names_uniprotkb": "Ankyrin repeat- and BTB/POZ domain-containing protein 3-A; BTB/POZ domain-containing protein 11-A", "protein_names_refseq": "BTB (POZ) domain containing 11; BTB/POZ domain-containing protein 11-A; ankyrin repeat and BTB/POZ domain-containing protein 3-A; ankyrin repeat- and BTB/POZ domain-containing protein 3-A isoform 2", "tax_id": 7955, "disease": "", "pathway": " (dre:562893)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: partial sample support SAMEA3505370, SAMEA3505371 [ECO:0000350] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL928936.9. On Sep 1, 2006 this sequence version replaced XP_691353.1. Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1., [RefSeq]; May support cell-type-specific synaptic function., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1MTD0", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0046982 protein heterodimerization activity;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0016020 membrane;GO:0000786 nucleosome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1LVW0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1RLU9-1", "uniprot_id": [ { "id": "CDK15_DANRE", "url": "https://www.uniprot.org/uniprot/Q1RLU9", "type": "external" } ], "mass": 47907.0, "length": 418, "protein_name": "Cyclin-dependent kinase 15", "gene_name": "cdk15", "organism": "Zebrafish", "refseq_name": "cyclin-dependent kinase 15", "refseq_ac": [ { "id": "NP_001035398", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035398", "type": "external" } ], "gene_names_uniprotkb": "cdk15; pftk2; zgc:136819", "gene_names_refseq": "cdk15; zgc:136819", "protein_names_uniprotkb": "Cyclin-dependent kinase 15; 2.7.11.22; Cell division protein kinase 15", "protein_names_refseq": "cell division protein kinase 15; cyclin-dependent kinase 15; pftk2; serine/threonine-protein kinase PFTAIRE-2", "tax_id": 7955, "disease": "", "pathway": " (dre:791619)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC115279.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC115279.1. On Nov 2, 2007 this sequence version replaced XP_001331257.1., [RefSeq]; Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0030332 cyclin binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:1901987 regulation of cell cycle phase transition", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1RLU9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q503Z8-1", "uniprot_id": [ { "id": "IRX6A_DANRE", "url": "https://www.uniprot.org/uniprot/Q503Z8", "type": "external" } ], "mass": 52408.0, "length": 477, "protein_name": "Iroquois homeobox protein 6a", "gene_name": "irx6a", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "irx6a; zgc:109993; ziro6a", "gene_names_refseq": "", "protein_names_uniprotkb": "Iroquois homeobox protein 6a", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:474317)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15133664;21046643;23594743;33891002", "class_list": "", "function": "Transcription factor (By similarity). Binds to the iroquois binding site (IBS) motif of target genes to regulate gene expression; functions as a transcriptional activator or repressor (By similarity). In concert with irx5a, plays a role in visual performance (PubMed:33891002)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B5DDN4", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0030182 neuron differentiation;GO:0048468 cell development", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q503Z8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q4KMI4-1", "uniprot_id": [ { "id": "REEP2_DANRE", "url": "https://www.uniprot.org/uniprot/Q4KMI4", "type": "external" } ], "mass": 30110.0, "length": 268, "protein_name": "Receptor expression-enhancing protein 2", "gene_name": "reep2", "organism": "Zebrafish", "refseq_name": "receptor expression-enhancing protein 2", "refseq_ac": [ { "id": "NP_001025398", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025398", "type": "external" } ], "gene_names_uniprotkb": "reep2; zgc:110128", "gene_names_refseq": "reep2; zgc:110128", "protein_names_uniprotkb": "Receptor expression-enhancing protein 2", "protein_names_refseq": "receptor expression-enhancing protein 2", "tax_id": 7955, "disease": "hereditary spastic paraplegia 72B (Disease Ontology:DOID:0070642); hereditary spastic paraplegia 31 (Disease Ontology:DOID:0110782); hereditary spastic paraplegia 72A (Disease Ontology:DOID:0110817)", "pathway": " (dre:568927)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC098549.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505375, SAMEA3505376 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC098549.1. On Aug 6, 2005 this sequence version replaced XP_697379.1., [RefSeq]; May enhance the cell surface expression of odorant receptors., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0031883 taste receptor binding", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005881 cytoplasmic microtubule;GO:0071782 endoplasmic reticulum tubular network;GO:0016020 membrane", "go_biological_process": "GO:0071786 endoplasmic reticulum tubular network organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q4KMI4-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LYG0-1", "uniprot_id": [ { "id": "SPD2A_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LYG0", "type": "external" } ], "mass": 124906.0, "length": 1119, "protein_name": "SH3 and PX domain-containing protein 2A", "gene_name": "sh3pxd2aa; sh3pxd2a", "organism": "Zebrafish", "refseq_name": "SH3 and PX domain-containing protein 2A isoform X4", "refseq_ac": [ { "id": "XP_005171051", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171051", "type": "external" } ], "gene_names_uniprotkb": "sh3pxd2aa; sh3pxd2a; TSK5; sh3pxd2a; si:dkey-82d4.2", "gene_names_refseq": "TSK5; sh3pxd2aa; sh3pxd2a; si:dkey-82d4.2", "protein_names_uniprotkb": "SH3 and PX domain-containing protein 2A", "protein_names_refseq": "SH3 and PX domain-containing protein 2A isoform X4", "tax_id": 7955, "disease": "", "pathway": " (dre:562018); (R-DRE-8941237); (R-DRE-9013148)", "pathway_count": 3, "publication_count": 10, "publication_id_list": "17900370;21799874;22973180;23594743;24942242;25810455;26048245;26469318;27189481;30970187", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation., [UniProtKB]; Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035091 phosphatidylinositol binding;GO:0016176 superoxide-generating NADPH oxidase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0002102 podosome", "go_biological_process": "GO:0001755 neural crest cell migration;GO:0072593 reactive oxygen species metabolic process;GO:0006801 superoxide metabolic process;GO:0042554 superoxide anion generation;GO:0048920 posterior lateral line neuromast primordium migration", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q1LYG0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LVC2-1", "uniprot_id": [ { "id": "JARD2_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LVC2", "type": "external" } ], "mass": 148226.0, "length": 1319, "protein_name": "Protein Jumonji", "gene_name": "jarid2b", "organism": "Zebrafish", "refseq_name": "protein Jumonji", "refseq_ac": [ { "id": "NP_001189388", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189388", "type": "external" } ], "gene_names_uniprotkb": "jarid2b; jmj; si:dkey-211c3.1", "gene_names_refseq": "jarid2b; si:dkey-211c3.1", "protein_names_uniprotkb": "Protein Jumonji; Jumonji/ARID domain-containing protein 2", "protein_names_refseq": "jumonji, AT rich interactive domain 2b; jumonji/ARID domain-containing protein 2; protein Jumonji", "tax_id": 7955, "disease": "autistic disorder (Disease Ontology:DOID:12849); aortic valve stenosis (Disease Ontology:DOID:1712)", "pathway": " (dre:558456); (R-DRE-212300)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: partial sample support SAMEA4476775, SAMEA4476806 [ECO:0000350] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000019.1. On Jan 29, 2011 this sequence version replaced XP_686761.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Regulator of histone methyltransferase complexes that plays an essential role in embryonic development. Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells. Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, thereby playing a key role in differentiation of embryonic stem cells and normal development (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0035098 ESC/E(Z) complex;GO:0035097 histone methyltransferase complex;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0048863 stem cell differentiation;GO:0010468 regulation of gene expression;GO:0048731 system development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1LVC2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q4V8Y7-1", "uniprot_id": [ { "id": "AF1L1_DANRE", "url": "https://www.uniprot.org/uniprot/Q4V8Y7", "type": "external" } ], "mass": 84166.0, "length": 746, "protein_name": "Actin filament-associated protein 1-like 1", "gene_name": "afap1l1a; afap1l1", "organism": "Zebrafish", "refseq_name": "actin filament-associated protein 1-like 1", "refseq_ac": [ { "id": "NP_001025384", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025384", "type": "external" } ], "gene_names_uniprotkb": "afap1l1a; afap1l1; afap1l1; zgc:114084", "gene_names_refseq": "afap1l1a; afap1l1; zgc:114084", "protein_names_uniprotkb": "Actin filament-associated protein 1-like 1; AFAP1-like protein 1", "protein_names_refseq": "AFAP1-like protein 1; actin filament-associated protein 1-like 1", "tax_id": 7955, "disease": "", "pathway": " (dre:566757)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC097145.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC097145.1. On Aug 6, 2005 this sequence version replaced XP_695133.1., [RefSeq]; May be involved in podosome and invadosome formation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0002102 podosome;GO:0001725 stress fiber;GO:0042995 cell projection;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q4V8Y7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q568B7-1", "uniprot_id": [ { "id": "QTMAN_DANRE", "url": "https://www.uniprot.org/uniprot/Q568B7", "type": "external" } ], "mass": 49737.0, "length": 433, "protein_name": "tRNA-queuosine alpha-mannosyltransferase", "gene_name": "gtdc1; qtman", "organism": "Zebrafish", "refseq_name": "tRNA-queuosine alpha-mannosyltransferase", "refseq_ac": [ { "id": "NP_001017560", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017560", "type": "external" } ], "gene_names_uniprotkb": "gtdc1; qtman; QTMAN; gtdc1; si:dkey-52o2.3; zgc:110568", "gene_names_refseq": "gtdc1; qtman; zgc:110568", "protein_names_uniprotkb": "tRNA-queuosine alpha-mannosyltransferase; 2.4.1.110; Glycosyltransferase-like domain-containing protein 1; QTMAN", "protein_names_refseq": "glycosyltransferase-like domain containing 1; glycosyltransferase-like domain-containing protein 1; tRNA-queuosine alpha-mannosyltransferase", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "23594743;28365779;37992713", "class_list": "glycogene;glycosyltransferase", "function": "##Evidence-Data-START## Transcript exon combination :: BC092932.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476728, SAMEA4476749 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC092932.1. On Jul 6, 2005 this sequence version replaced XP_701787.1., [RefSeq]; Glycosyltransferase that specifically catalyzes mannosylation of cytoplasmic tRNA(Asp) modified with queuosine at position 34 (queuosine(34)). Mannosylates the cyclopentene moiety of queuosine(34) in tRNA(Asp) to form mannosyl-queuosine(34). Mannosylation of queuosine(34) in tRNA(Asp) is required to slow-down elongation at cognate codons, GAC and GAU, thereby regulating protein translation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; We utilized a zebrafish model to demonstrate a role for GTDC1 in the development of the central nervous system. Our findings highlight the importance of combining sequencing technologies with the iPSC technology for NDDs modelling that could be applied for personalized medicine., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B0S8J7", "ec_number_list": [ { "id": "2.4.1.110", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.110", "type": "external" } ], "go_molecular_function": "GO:0016438 tRNA-queuosine(34) beta-mannosyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006417 regulation of translation;GO:0006400 tRNA modification;GO:0007417 central nervous system development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q568B7-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q32PW3-1", "uniprot_id": [ { "id": "TAF2_DANRE", "url": "https://www.uniprot.org/uniprot/Q32PW3", "type": "external" } ], "mass": 136526.0, "length": 1191, "protein_name": "Transcription initiation factor TFIID subunit 2", "gene_name": "taf2", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "taf2; TAFII-150; TAFII150; fc30f02; fc56a05; wu:fc30f02; wu:fc56a05", "gene_names_refseq": "", "protein_names_uniprotkb": "Transcription initiation factor TFIID subunit 2; TAF(II)150; TAFII-150; TAFII150; TBP-associated factor 150 kDa; Transcription initiation factor TFIID 150 kDa subunit", "protein_names_refseq": "", "tax_id": 7955, "disease": "autosomal recessive intellectual developmental disorder 40 (Disease Ontology:DOID:0081205)", "pathway": " (dre:324486); (R-DRE-674695); (R-DRE-6804756); (R-DRE-73776); (R-DRE-73779); (R-DRE-75953); (R-DRE-76042)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "15256591", "class_list": "", "function": "The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit tbp, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of tbp and TBP-associated factors (TAFs)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5BJ13;Q6DGD5;Q6DRH8", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005669 transcription factor TFIID complex", "go_biological_process": "GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0051123 RNA polymerase II preinitiation complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q32PW3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q4V8V2-1", "uniprot_id": [ { "id": "NUD17_DANRE", "url": "https://www.uniprot.org/uniprot/Q4V8V2", "type": "external" } ], "mass": 32712.0, "length": 300, "protein_name": "m7GpppN-mRNA hydrolase NUDT17", "gene_name": "nudt17", "organism": "Zebrafish", "refseq_name": "m7GpppN-mRNA hydrolase NUDT17", "refseq_ac": [ { "id": "NP_001025274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025274", "type": "external" } ], "gene_names_uniprotkb": "nudt17; zgc:114128", "gene_names_refseq": "nudt17; zgc:114128", "protein_names_uniprotkb": "m7GpppN-mRNA hydrolase NUDT17; 3.6.1.62; Nucleoside diphosphate-linked moiety X motif 17; Nudix motif 17", "protein_names_refseq": "m7GpppN-mRNA hydrolase NUDT17; nucleoside diphosphate-linked moiety X motif 17; nudix motif 17", "tax_id": 7955, "disease": "", "pathway": " (dre:556651)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC097186.1, EE704039.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA4476740, SAMEA4476750 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC097186.1. On Aug 6, 2005 this sequence version replaced XP_684592.1., [RefSeq]; Acts as a decapping enzyme capable of hydrolyzing monomethylated capped RNAs (in vitro). Hydrolyzes monomethylated capped RNA after alpha and beta phosphates to form N(7)-methyl-GDP. Shows low activity towards unmethylated capped RNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.62", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0035529 NADH pyrophosphatase activity;GO:0140933 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0019677 NAD+ catabolic process;GO:0006742 NADP+ catabolic process;GO:0110154 RNA decapping", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q4V8V2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q503I9-1", "uniprot_id": [ { "id": "GLD2_DANRE", "url": "https://www.uniprot.org/uniprot/Q503I9", "type": "external" } ], "mass": 55562.0, "length": 489, "protein_name": "Poly(A) RNA polymerase GLD2", "gene_name": "tent2", "organism": "Zebrafish", "refseq_name": "poly(A) RNA polymerase GLD2", "refseq_ac": [ { "id": "NP_001018436", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018436", "type": "external" } ], "gene_names_uniprotkb": "tent2; papd4; zgc:110560", "gene_names_refseq": "papd4; tent2; zgc:110560", "protein_names_uniprotkb": "Poly(A) RNA polymerase GLD2; 2.7.7.19; PAP-associated domain-containing protein 4", "protein_names_refseq": "PAP associated domain containing 4; PAP-associated domain-containing protein 4; TUTase2; poly(A) RNA polymerase GLD2", "tax_id": 7955, "disease": "", "pathway": " (dre:553626)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC095312.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC095312.1. On Jul 6, 2005 this sequence version replaced XP_701874.1., [RefSeq]; Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. May not play a role in replication-dependent histone mRNA degradation (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19", "type": "external" }, { "id": "2.7.7.52", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.52", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:1990817 poly(A) RNA polymerase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0010468 regulation of gene expression;GO:0031124 mRNA 3'-end processing;GO:0031123 RNA 3'-end processing;GO:2000626 negative regulation of miRNA catabolic process;GO:0006397 mRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q503I9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q56A35-1", "uniprot_id": [ { "id": "ARP2B_DANRE", "url": "https://www.uniprot.org/uniprot/Q56A35", "type": "external" } ], "mass": 44702.0, "length": 394, "protein_name": "Actin-related protein 2-B", "gene_name": "actr2b", "organism": "Zebrafish", "refseq_name": "actin-related protein 2-B", "refseq_ac": [ { "id": "NP_001017542", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017542", "type": "external" } ], "gene_names_uniprotkb": "actr2b; actr2; arp2b; si:dkey-66m17.2; zgc:110550", "gene_names_refseq": "actr2b; actr2; zgc:110550", "protein_names_uniprotkb": "Actin-related protein 2-B; Actin-like protein 2-B", "protein_names_refseq": "ARP2 actin related protein 2b homolog; ARP2 actin-related protein 2; actin-like protein 2-B; actin-related protein 2-B", "tax_id": 7955, "disease": "colorectal carcinoma (Disease Ontology:DOID:0080199); lung disease (Disease Ontology:DOID:850)", "pathway": " (dre:554861); (R-DRE-2029482); (R-DRE-3928662); (R-DRE-5663213); (R-DRE-6798695)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: ERR4321680.503813.1, SRR26395015.161859.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA4476731, SAMEA4476732 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On or before Jun 27, 2025 this sequence version replaced XP_005169567.1, XP_701773.1., [RefSeq]; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (By similarity). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (By similarity). Seems to contact the pointed end of the daughter actin filament (By similarity). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (By similarity). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005200 structural constituent of cytoskeleton;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005938 cell cortex;GO:0035861 site of double-strand break;GO:0005885 Arp2/3 protein complex", "go_biological_process": "GO:0060319 primitive erythrocyte differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0034314 Arp2/3 complex-mediated actin nucleation;GO:1905168 positive regulation of double-strand break repair via homologous recombination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q56A35-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q2LE08-1", "uniprot_id": [ { "id": "FXP1B_DANRE", "url": "https://www.uniprot.org/uniprot/Q2LE08", "type": "external" } ], "mass": 73845.0, "length": 659, "protein_name": "Forkhead box protein P1-B", "gene_name": "foxp1b", "organism": "Zebrafish", "refseq_name": "forkhead box protein P1-B", "refseq_ac": [ { "id": "NP_001034726", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034726", "type": "external" } ], "gene_names_uniprotkb": "foxp1b; foxp1; im:7139058; wu:fc83a06", "gene_names_refseq": "foxp1b; foxp1; im:7139058; wu:fc83a06", "protein_names_uniprotkb": "Forkhead box protein P1-B", "protein_names_refseq": "forkhead box P1; forkhead box protein P1-B", "tax_id": 7955, "disease": "specific developmental disorder (Disease Ontology:DOID:0060038); complex cortical dysplasia with other brain malformations (Disease Ontology:DOID:0090131); intellectual disability-severe speech delay-mild dysmorphism syndrome (Disease Ontology:DOID:0111331); trichostrongyloidiasis (Disease Ontology:DOID:1255); Huntington's disease (Disease Ontology:DOID:12858); congenital heart disease (Disease Ontology:DOID:1682); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); esophagus adenocarcinoma (Disease Ontology:DOID:4914); schizophrenia (Disease Ontology:DOID:5419); congestive heart failure (Disease Ontology:DOID:6000); hepatocellular carcinoma (Disease Ontology:DOID:684); peritonitis (Disease Ontology:DOID:8283); Barrett's esophagus (Disease Ontology:DOID:9206); hypoplastic left heart syndrome (Disease Ontology:DOID:9955)", "pathway": " (dre:569047)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "17876603;38456494", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: DQ333303.2 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ333303.2. On Mar 2, 2006 this sequence version replaced XP_697501.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Foxp and Skor family proteins control differentiation of Purkinje cells from Ptf1a- and Neurog1-expressing progenitors in zebrafish., [RefSeq, PubMed]; Prominent foxp1 expression is detected in many regions of the developing central nervous system, especially in midbrain-hindbrain boundary, hindbrain, and spinal cord., [RefSeq, PubMed]; Transcriptional repressor., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q2LE08-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q503S1-1", "uniprot_id": [ { "id": "FIGN_DANRE", "url": "https://www.uniprot.org/uniprot/Q503S1", "type": "external" } ], "mass": 79202.0, "length": 736, "protein_name": "Fidgetin", "gene_name": "fign", "organism": "Zebrafish", "refseq_name": "fidgetin", "refseq_ac": [ { "id": "NP_001018411", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018411", "type": "external" } ], "gene_names_uniprotkb": "fign; zgc:110229", "gene_names_refseq": "fign; zgc:110229", "protein_names_uniprotkb": "Fidgetin", "protein_names_refseq": "fidgetin", "tax_id": 7955, "disease": "", "pathway": " (dre:553599)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC095207.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505381 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC095207.1., [RefSeq]; ATP-dependent microtubule severing protein. Severs microtubules along their length and depolymerizes their ends, primarily the minus-end, suppressing microtubule growth from and attachment to centrosomes. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008568 microtubule severing ATPase activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005874 microtubule;GO:0016363 nuclear matrix", "go_biological_process": "GO:0051013 microtubule severing;GO:0051301 cell division;GO:0009653 anatomical structure morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q503S1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q32PP3-1", "uniprot_id": [ { "id": "PDK1L_DANRE", "url": "https://www.uniprot.org/uniprot/Q32PP3", "type": "external" } ], "mass": 38205.0, "length": 341, "protein_name": "Serine/threonine-protein kinase pdik1l", "gene_name": "pdik1l", "organism": "Zebrafish", "refseq_name": "serine/threonine-protein kinase pdik1l", "refseq_ac": [ { "id": "NP_001032789", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032789", "type": "external" } ], "gene_names_uniprotkb": "pdik1l; wu:fc95a02; zgc:123209", "gene_names_refseq": "pdik1l; wu:fc95a02; zgc:123209", "protein_names_uniprotkb": "Serine/threonine-protein kinase pdik1l; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase pdik1l", "tax_id": 7955, "disease": "", "pathway": " (dre:569665)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC108040.1, GDQH01009081.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EG569238.1, EH552212.1, JBMGRA010000019.1 and BC108040.1. On Apr 15, 2009 this sequence version replaced NP_001032789.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity;GO:0016301 kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0010972 negative regulation of G2/M transition of mitotic cell cycle;GO:0110031 negative regulation of G2/MI transition of meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32PP3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q52KB5-1", "uniprot_id": [ { "id": "ZBT24_DANRE", "url": "https://www.uniprot.org/uniprot/Q52KB5", "type": "external" } ], "mass": 75410.0, "length": 672, "protein_name": "Zinc finger and BTB domain-containing protein 24", "gene_name": "zbtb24", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "zbtb24; zfp450; zgc:194556", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger and BTB domain-containing protein 24; Zinc finger protein 450", "protein_names_refseq": "", "tax_id": 7955, "disease": "immunodeficiency-centromeric instability-facial anomalies syndrome (Disease Ontology:DOID:0090007); immunodeficiency-centromeric instability-facial anomalies syndrome 2 (Disease Ontology:DOID:0090009)", "pathway": " (dre:553955)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "15526281;23594743;24240475;27189481;30484769;30905685;35356281", "class_list": "", "function": "May be involved in BMP2-induced transcription., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B3DIU4", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0002682 regulation of immune system process;GO:0001817 regulation of cytokine production", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q52KB5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q503M4-1", "uniprot_id": [ { "id": "MT12B_DANRE", "url": "https://www.uniprot.org/uniprot/Q503M4", "type": "external" } ], "mass": 51853.0, "length": 477, "protein_name": "Monocarboxylate transporter 12-B", "gene_name": "slc16a12b", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "slc16a12b; im:7140871; slc16a12; wu:fc44b08; zgc:110441", "gene_names_refseq": "", "protein_names_uniprotkb": "Monocarboxylate transporter 12-B; MCT 12-B; Solute carrier family 16 member 12-B", "protein_names_refseq": "", "tax_id": 7955, "disease": "cataract 47 (Disease Ontology:DOID:0070353)", "pathway": " (dre:449947)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "26469318;30252882", "class_list": "", "function": "Functions as a transporter for creatine and as well for its precursor guanidinoacetate. Transport of creatine and GAA is independent of resting membrane potential and extracellular Na(+), Cl(-), or pH. Contributes to the process of creatine biosynthesis and distribution., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0005308 creatine transmembrane transporter activity;GO:0015292 uniporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0046449 creatinine metabolic process;GO:0015881 creatine transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q503M4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LVL2-1", "uniprot_id": [ { "id": "Q1LVL2_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LVL2", "type": "external" } ], "mass": 106936.0, "length": 966, "protein_name": "Alanine--tRNA ligase", "gene_name": "aars1", "organism": "Zebrafish", "refseq_name": "alanine--tRNA ligase, cytoplasmic isoform X1", "refseq_ac": [ { "id": "XP_005159107", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005159107", "type": "external" } ], "gene_names_uniprotkb": "aars1; AARS; aars; im:7146712; si:ch211-223o1.6; wu:fc48h07; zgc:113920", "gene_names_refseq": "aars1; aars; im:7146712; si:ch211-223o1.6; wu:fc48h07; zgc:113920", "protein_names_uniprotkb": "Alanine--tRNA ligase; 6.1.1.7; Protein lactyltransferase AARS1", "protein_names_refseq": "alanine--tRNA ligase, cytoplasmic isoform X1", "tax_id": 7955, "disease": "nonphotosensitive trichothiodystrophy 8 (Disease Ontology:DOID:0061023); developmental and epileptic encephalopathy 29 (Disease Ontology:DOID:0080451); Charcot-Marie-Tooth disease axonal type 2N (Disease Ontology:DOID:0110177); leukodystrophy (Disease Ontology:DOID:10579)", "pathway": " (dre:324940)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "16109975;25534026;27895053;28252024;28934368;30124830;34872004;35929539", "class_list": "", "function": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain., [UniProtKB, HAMAP, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M2B5M3", "ec_number_list": [ { "id": "6.1.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.7", "type": "external" }, { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0000049 tRNA binding;GO:0004813 alanine-tRNA ligase activity;GO:0002161 aminoacyl-tRNA deacylase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006419 alanyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q1LVL2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q4KMC8-1", "uniprot_id": [ { "id": "ALDCA_DANRE", "url": "https://www.uniprot.org/uniprot/Q4KMC8", "type": "external" } ], "mass": 39870.0, "length": 364, "protein_name": "Fructose-bisphosphate aldolase C-A", "gene_name": "aldoca", "organism": "Zebrafish", "refseq_name": "fructose-bisphosphate aldolase C-A", "refseq_ac": [ { "id": "NP_001025123", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025123", "type": "external" } ], "gene_names_uniprotkb": "aldoca; aldocl; wu:fj56h04; zebrin II; zgc:112357", "gene_names_refseq": "aldoca; aldocl; wu:fj56h04; zgc:112357", "protein_names_uniprotkb": "Fructose-bisphosphate aldolase C-A; 4.1.2.13; Aldolase C-like; Brain-type aldolase-A", "protein_names_refseq": "aldolase c, fructose-bisphosphate, like; fructose-bisphosphate aldolase C-A; zebrin II", "tax_id": 7955, "disease": "stroke (Disease Ontology:DOID:0051061); chromosome 16p11.2 deletion syndrome, 593-kb (Disease Ontology:DOID:0070515); autoimmune disease of the nervous system (Disease Ontology:DOID:438); borna disease (Disease Ontology:DOID:5154); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dre:792692)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "17013923;19371731", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC098624.1, GFIL01000893.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505379, SAMEA3505380 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jul 28, 2025 this sequence version replaced NP_001025123.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Catalyzes the reversible conversion of beta-D-fructose 1,6-bisphosphate (FBP) into two triose phosphate and plays a key role in glycolysis and gluconeogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" } ], "go_molecular_function": "GO:0004332 fructose-bisphosphate aldolase activity;GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0004674 protein serine/threonine kinase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006096 glycolytic process;GO:0030388 fructose 1,6-bisphosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q4KMC8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q503E1-1", "uniprot_id": [ { "id": "INT11_DANRE", "url": "https://www.uniprot.org/uniprot/Q503E1", "type": "external" } ], "mass": 67592.0, "length": 598, "protein_name": "Integrator complex subunit 11", "gene_name": "cpsf3l; ints11", "organism": "Zebrafish", "refseq_name": "integrator complex subunit 11", "refseq_ac": [ { "id": "NP_001018457", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018457", "type": "external" } ], "gene_names_uniprotkb": "cpsf3l; ints11; cpsf3l; ints11; zgc:110671", "gene_names_refseq": "cpsf3l; ints11; zgc:110671", "protein_names_uniprotkb": "Integrator complex subunit 11; 3.1.27.-; CPSF3-like protein; Cleavage and polyadenylation-specific factor 3-like protein; Int11", "protein_names_refseq": "CPSF3-like protein; cleavage and polyadenylation specific factor 3-like; cleavage and polyadenylation-specific factor 3-like protein; int11; integrator complex subunit 11", "tax_id": 7955, "disease": "neurodevelopmental disorder with motor and language delay, ocular defects, and brain abnormalities (Disease Ontology:DOID:0081387)", "pathway": " (dre:553648); (R-DRE-6807505)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC095364.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC095364.1. On Jul 6, 2005 this sequence version replaced XP_701893.1., [RefSeq]; RNA endonuclease component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes. The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit POLR2A/RPB1 and SUPT5H/SPT5, (2) degrading the exiting nascent RNA transcript via endonuclease activity and (3) promoting the release of Pol II from bound DNA. The integrator complex is also involved in terminating the synthesis of non-coding Pol II transcripts, such as enhancer RNAs (eRNAs), small nuclear RNAs (snRNAs), telomerase RNAs and long non-coding RNAs (lncRNAs). Within the integrator complex, INTS11 constitutes the RNA endonuclease subunit that degrades exiting nascent RNA transcripts., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.1.27.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.27.-", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0016787 hydrolase activity;GO:0046872 metal ion binding;GO:0004521 RNA endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0032039 integrator complex;GO:0160232 INTAC complex", "go_biological_process": "GO:0043484 regulation of RNA splicing;GO:0016180 snRNA processing;GO:0034472 snRNA 3'-end processing;GO:0160240 RNA polymerase II transcription initiation surveillance", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q503E1-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LUA8-1", "uniprot_id": [ { "id": "EI3EB_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LUA8", "type": "external" } ], "mass": 52602.0, "length": 446, "protein_name": "Eukaryotic translation initiation factor 3 subunit E-B", "gene_name": "eif3eb", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "eif3eb; EIF3E; EIF3S6; eif3s6b; im:7147439; si:ch211-129b17.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit E-B; Eukaryotic translation initiation factor 3 subunit 6-B; eIF3e-B", "protein_names_refseq": "", "tax_id": 7955, "disease": "intermittent claudication (Disease Ontology:DOID:3669)", "pathway": " (dre:561049)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23594743;27189481;28252024;33809683", "class_list": "", "function": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1LUA7", "ec_number_list": [], "go_molecular_function": "GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e;GO:0005852 eukaryotic translation initiation factor 3 complex", "go_biological_process": "GO:0006413 translational initiation;GO:0001732 formation of cytoplasmic translation initiation complex", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q1LUA8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q32PP1-1", "uniprot_id": [ { "id": "MRNIP_DANRE", "url": "https://www.uniprot.org/uniprot/Q32PP1", "type": "external" } ], "mass": 44921.0, "length": 395, "protein_name": "MRN complex-interacting protein", "gene_name": "mrnip", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "mrnip; si:dkey-177p5.2; zgc:123335", "gene_names_refseq": "", "protein_names_uniprotkb": "MRN complex-interacting protein; MRN-interacting protein", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "26469318;27189481", "class_list": "", "function": "Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006281 DNA repair;GO:0045860 positive regulation of protein kinase activity;GO:0006974 DNA damage response;GO:0010212 response to ionizing radiation;GO:0007095 mitotic G2 DNA damage checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q32PP1-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q2YDQ5-1", "uniprot_id": [ { "id": "FBXL5_DANRE", "url": "https://www.uniprot.org/uniprot/Q2YDQ5", "type": "external" } ], "mass": 75732.0, "length": 679, "protein_name": "F-box/LRR-repeat protein 5", "gene_name": "fbxl5", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "fbxl5; wu:fb52d06", "gene_names_refseq": "", "protein_names_uniprotkb": "F-box/LRR-repeat protein 5; F-box and leucine-rich repeat protein 5", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (R-DRE-8951664); (R-DRE-917937); (R-DRE-983168)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "16109975;26469318", "class_list": "", "function": "Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of ireb2/irp2. Upon high iron and oxygen level, it specifically recognizes and binds ireb2/irp2, promoting its ubiquitination and degradation by the proteasome (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005506 iron ion binding;GO:0051536 iron-sulfur cluster binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0048471 perinuclear region of cytoplasm;GO:0019005 SCF ubiquitin ligase complex", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis;GO:0016567 protein ubiquitination;GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q2YDQ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q58EJ9-1", "uniprot_id": [ { "id": "MARC1_DANRE", "url": "https://www.uniprot.org/uniprot/Q58EJ9", "type": "external" } ], "mass": 36716.0, "length": 325, "protein_name": "Mitochondrial amidoxime-reducing component 1", "gene_name": "marc1; mtarc1", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "marc1; mtarc1; marc1; marc2; mosc1; mosc2; mtarc1; sb:cb792; zgc:110783", "gene_names_refseq": "", "protein_names_uniprotkb": "Mitochondrial amidoxime-reducing component 1; 1.7.-.-; mARC1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:378742); (R-DRE-211945)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "26469318;27189481;28252024;29344929;35295584", "class_list": "", "function": "Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles. As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability. May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis. Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.7.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.7.-.-", "type": "external" } ], "go_molecular_function": "GO:0030151 molybdenum ion binding;GO:0008940 nitrate reductase activity;GO:0030170 pyridoxal phosphate binding;GO:0043546 molybdopterin cofactor binding;GO:0003824 catalytic activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0042126 nitrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q58EJ9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5BJJ7-1", "uniprot_id": [ { "id": "BCCIP_DANRE", "url": "https://www.uniprot.org/uniprot/Q5BJJ7", "type": "external" } ], "mass": 33884.0, "length": 301, "protein_name": "Protein BCCIP homolog", "gene_name": "bccip", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "bccip; mp:zf637-1-000774; zgc:110272", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein BCCIP homolog", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:541348)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16109975;26469318", "class_list": "", "function": "During interphase, required for microtubule organizing and anchoring activities. During mitosis, required for the organization and stabilization of the spindle pole. May promote cell cycle arrest and DNA repair., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005814 centriole;GO:0097431 mitotic spindle pole;GO:0000922 spindle pole", "go_biological_process": "GO:0006281 DNA repair;GO:0090307 mitotic spindle assembly;GO:0000226 microtubule cytoskeleton organization;GO:0007052 mitotic spindle organization;GO:0034453 microtubule anchoring", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q5BJJ7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q58A48-1", "uniprot_id": [ { "id": "TSK_DANRE", "url": "https://www.uniprot.org/uniprot/Q58A48", "type": "external" } ], "mass": 37776.0, "length": 347, "protein_name": "Tsukushi", "gene_name": "tsku", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "tsku; Z-TSK; fd51d02; lrcc54; tsk; wu:fd51d02; zgc:56201", "gene_names_refseq": "", "protein_names_uniprotkb": "Tsukushi; Leucine-rich repeat-containing protein 54; Z-TSK", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:325958)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "15363410;15520368;20802085;20935258;21669877;23201900;25094061;26469318;31680844;37884489", "class_list": "", "function": "Contributes to various developmental events through its interactions with multiple signaling pathways (By similarity). Dorsalizing factor which functions as an inhibitor of bone morphogenetic proteins during gastrulation (PubMed:15363410)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q7ZUT1", "ec_number_list": [], "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0005576 extracellular region", "go_biological_process": "GO:0097009 energy homeostasis;GO:0003431 growth plate cartilage chondrocyte development;GO:0098868 bone growth", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q58A48-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q4KM14-1", "uniprot_id": [ { "id": "TSP1L_DANRE", "url": "https://www.uniprot.org/uniprot/Q4KM14", "type": "external" } ], "mass": 35853.0, "length": 316, "protein_name": "tRNA selenocysteine 1-associated protein 1-like", "gene_name": "trnau1apb; trnau1apl", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "trnau1apb; trnau1apl; secp43; secpl; trnau1apl; trnau1ap; trspap1; wu:fa56b07; wu:fc12c07; wu:fc69f09; zgc:113964; zgc:77884", "gene_names_refseq": "", "protein_names_uniprotkb": "tRNA selenocysteine 1-associated protein 1-like; tRNA selenocysteine 1-associated protein 1; tRNA selenocysteine-associated protein 1", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:791478)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "16109975;20659579;23737534;25064324;25750091;26469318;34488355", "class_list": "", "function": "Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0006412 translation;GO:0006376 mRNA splice site recognition", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q4KM14-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q58EL2-1", "uniprot_id": [ { "id": "NACHO_DANRE", "url": "https://www.uniprot.org/uniprot/Q58EL2", "type": "external" } ], "mass": 17887.0, "length": 160, "protein_name": "Novel acetylcholine receptor chaperone", "gene_name": "tmem35a; tmem35", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "tmem35a; tmem35; Xp18; flj14084; nacho; tmem35a; tmem35; wu:fc41e12; zgc:110832", "gene_names_refseq": "", "protein_names_uniprotkb": "Novel acetylcholine receptor chaperone; Transmembrane protein 35A", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:791920)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12706884;25114259;26469318;27189481", "class_list": "", "function": "Molecular chaperone which mediates the proper assembly and functional expression of the nicotinic acetylcholine receptors (nAChRs) throughout the brain (By similarity). Essential for the proper folding, assembly, function and surface trafficking of alpha-7 (CHRNA7), alpha-4-beta-2, alpha-3-beta-2 and alpha-3-beta-4 receptors (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030548 acetylcholine receptor regulator activity", "go_cellular_component": "GO:0005778 peroxisomal membrane;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:2000010 positive regulation of protein localization to cell surface;GO:0051131 chaperone-mediated protein complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q58EL2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q4VBV9-1", "uniprot_id": [ { "id": "NIT2_DANRE", "url": "https://www.uniprot.org/uniprot/Q4VBV9", "type": "external" } ], "mass": 30366.0, "length": 277, "protein_name": "Omega-amidase NIT2", "gene_name": "nit2", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "nit2; zgc:109720", "gene_names_refseq": "", "protein_names_uniprotkb": "Omega-amidase NIT2; 3.5.1.3; Nitrilase homolog 2", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:402904); (R-DRE-6798695)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "15520368;25534026;26469318;28252024", "class_list": "", "function": "Has omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting 2-oxoglutaramate and 2-oxosuccinamate to biologically useful 2-oxoglutarate and oxaloacetate, respectively., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6TGW8", "ec_number_list": [ { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "1.8.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.3.2", "type": "external" }, { "id": "2.7.1.35", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.35", "type": "external" }, { "id": "3.5.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1", "type": "external" }, { "id": "3.4.24.7", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.7", "type": "external" }, { "id": "3.4.21.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.4", "type": "external" }, { "id": "3.2.1.166", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.166", "type": "external" }, { "id": "3.5.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.3", "type": "external" }, { "id": "4.1.2.13", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.13", "type": "external" } ], "go_molecular_function": "GO:0050152 omega-amidase activity;GO:0106008 2-oxoglutaramate amidase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006528 asparagine metabolic process;GO:0006107 oxaloacetate metabolic process;GO:0006541 glutamine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q4VBV9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q503V9-1", "uniprot_id": [ { "id": "ENDUB_DANRE", "url": "https://www.uniprot.org/uniprot/Q503V9", "type": "external" } ], "mass": 32286.0, "length": 282, "protein_name": "Uridylate-specific endoribonuclease B", "gene_name": "endou2; endoub", "organism": "Zebrafish", "refseq_name": "uridylate-specific endoribonuclease B", "refseq_ac": [ { "id": "NP_001018398", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018398", "type": "external" } ], "gene_names_uniprotkb": "endou2; endoub; endoub; zgc:110053", "gene_names_refseq": "endou2; endoub; zgc:110053", "protein_names_uniprotkb": "Uridylate-specific endoribonuclease B; 4.6.1.-; Protein endoU-B", "protein_names_refseq": "poly(U)-specific endoribonuclease-B; protein endoU-B; uridylate-specific endoribonuclease B; uridylate-specific endoribonuclease-B", "tax_id": 7955, "disease": "", "pathway": " (dre:553584)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC095160.1, CN503039.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505374 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC095160.1., [RefSeq]; Endoribonuclease that cleaves single-stranded RNAs at 5' of uridylates and releases a product with a 2',3'-cyclic phosphate at the 3'-end. The UU and GU sites are more efficiently cleaved than CU and AU sites., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0016787 hydrolase activity;GO:0046872 metal ion binding;GO:0004521 RNA endonuclease activity;GO:0016829 lyase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q503V9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LWE6-1", "uniprot_id": [ { "id": "BI2L2_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LWE6", "type": "external" } ], "mass": 57588.0, "length": 516, "protein_name": "BAR/IMD domain-containing adapter protein 2-like 2", "gene_name": "baiap2l2b; baiap2l2", "organism": "Zebrafish", "refseq_name": "BAR/IMD domain-containing adapter protein 2-like 2", "refseq_ac": [ { "id": "NP_001074273", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074273", "type": "external" } ], "gene_names_uniprotkb": "baiap2l2b; baiap2l2; baiap2l2; si:dkey-205o12.6; si:dkey-232h18.1", "gene_names_refseq": "baiap2l2b; baiap2l2; si:dkey-205o12.6; si:dkey-232h18.1", "protein_names_uniprotkb": "BAR/IMD domain-containing adapter protein 2-like 2; BAI1-associated protein 2-like protein 2; Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2", "protein_names_refseq": "BAI1-associated protein 2-like 2b; BAI1-associated protein 2-like 2; BAI1-associated protein 2-like protein 2; BAR/IMD domain-containing adapter protein 2-like 2; brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2", "tax_id": 7955, "disease": "", "pathway": " (dre:564798); (R-DRE-9035034)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA4476772, SAMN18715719 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BX571946.9. On Mar 11, 2007 this sequence version replaced XP_693220.2., [RefSeq]; Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane structures., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1LWD6", "ec_number_list": [], "go_molecular_function": "GO:0008289 lipid binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0007009 plasma membrane organization;GO:0051017 actin filament bundle assembly;GO:0051764 actin crosslink formation;GO:0030838 positive regulation of actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1LWE6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1RMA6-1", "uniprot_id": [ { "id": "PARI_DANRE", "url": "https://www.uniprot.org/uniprot/Q1RMA6", "type": "external" } ], "mass": 62469.0, "length": 568, "protein_name": "PCNA-interacting partner", "gene_name": "parpbp", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "parpbp; PARI; PARP1BP; pari; si:ch211-260p3.2; zgc:136263", "gene_names_refseq": "", "protein_names_uniprotkb": "PCNA-interacting partner; PARI; PARP-1 binding protein; PARP1-binding protein; PARPBP", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:678635)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "26469318;31415728;31969822;32196499;9409775", "class_list": "", "function": "Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000785 chromatin", "go_biological_process": "GO:2000042 negative regulation of double-strand break repair via homologous recombination;GO:0006281 DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q1RMA6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LUI2-1", "uniprot_id": [ { "id": "HDDC2_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LUI2", "type": "external" } ], "mass": 22919.0, "length": 200, "protein_name": "5'-deoxynucleotidase HDDC2", "gene_name": "hddc2", "organism": "Zebrafish", "refseq_name": "5'-deoxynucleotidase HDDC2", "refseq_ac": [ { "id": "NP_001038696", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038696", "type": "external" } ], "gene_names_uniprotkb": "hddc2; si:ch211-208c9.2; zgc:112330", "gene_names_refseq": "fb71h08; hddc2; wu:fb71h08; zgc:112330", "protein_names_uniprotkb": "5'-deoxynucleotidase HDDC2; 3.1.3.89; HD domain-containing protein 2", "protein_names_refseq": "5'-deoxynucleotidase HDDC2; novel IBR domain containing protein", "tax_id": 7955, "disease": "", "pathway": " (dre:554129)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH561545.1, EH540387.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000020.1. On or before May 27, 2009 this sequence version replaced NP_001019595.1, XP_700462.1., [RefSeq]; Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q502C2", "ec_number_list": [ { "id": "3.1.3.89", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.89", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0002953 5'-deoxynucleotidase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0009159 deoxyribonucleoside monophosphate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1LUI2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LUI6-1", "uniprot_id": [ { "id": "Q1LUI6_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LUI6", "type": "external" } ], "mass": 61399.0, "length": 543, "protein_name": "E3 ubiquitin-protein ligase RNF217", "gene_name": "rnf217", "organism": "Zebrafish", "refseq_name": "E3 ubiquitin-protein ligase RNF217", "refseq_ac": [ { "id": "NP_001076322", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076322", "type": "external" } ], "gene_names_uniprotkb": "rnf217; si:ch211-208c9.4; zgc:174567", "gene_names_refseq": "rnf217; si:ch211-208c9.4; zgc:174567", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF217; 2.3.2.31; RING finger protein 217", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF217; novel IBR domain containing protein", "tax_id": 7955, "disease": "", "pathway": " (dre:567287); (R-DRE-983168)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "26469318;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01032892.1, SRR32588735.2788356.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505372, SAMEA3505374 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000020.1. On Mar 15, 2007 this sequence version replaced XP_695671.2., [RefSeq]; E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the degradation of the iron exporter ferroportin/SLC40A1 and thus regulates iron homeostasis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NC36", "ec_number_list": [ { "id": "2.3.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.3.2.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34", "type": "external" }, { "id": "2.3.2.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26", "type": "external" }, { "id": "6.2.1.45", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.45", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "2.3.2.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.3.2.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0031624 ubiquitin conjugating enzyme binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q1LUI6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LUM3-1", "uniprot_id": [ { "id": "ENDUC_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LUM3", "type": "external" } ], "mass": 35239.0, "length": 309, "protein_name": "Uridylate-specific endoribonuclease C", "gene_name": "endouc", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "endouc; si:dkey-103i16.2", "gene_names_refseq": "", "protein_names_uniprotkb": "Uridylate-specific endoribonuclease C; 4.6.1.-; Protein endoU-C", "protein_names_refseq": "", "tax_id": 7955, "disease": "", "pathway": " (dre:562040)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "Endoribonuclease that cleaves single-stranded RNAs at 5' of uridylates and releases a product with a 2',3'-cyclic phosphate at the 3'-end. The UU and GU sites are more efficiently cleaved than CU and AU sites., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A3KNG8;B0S8H8", "ec_number_list": [ { "id": "4.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0016787 hydrolase activity;GO:0046872 metal ion binding;GO:0004521 RNA endonuclease activity;GO:0016829 lyase activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1LUM3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LUV9-1", "uniprot_id": [ { "id": "M1I1B_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LUV9", "type": "external" } ], "mass": 16811.0, "length": 147, "protein_name": "Mid1-interacting protein 1-B", "gene_name": "mid1ip1b", "organism": "Zebrafish", "refseq_name": "mid1-interacting protein 1-B", "refseq_ac": [ { "id": "NP_957126", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957126", "type": "external" } ], "gene_names_uniprotkb": "mid1ip1b; si:dkey-277i15.1; zgc:73223", "gene_names_refseq": "mid1ip1b; zgc:73223", "protein_names_uniprotkb": "Mid1-interacting protein 1-B", "protein_names_refseq": "mid1-interacting protein 1-B", "tax_id": 7955, "disease": "", "pathway": " (dre:393805); (R-DRE-200425)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "23594743;30174135", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH466055.1, EH581689.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476732, SAMEA4476742 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On Jun 18, 2024 this sequence version replaced NP_957126.1., [RefSeq]; Involved in stabilization of microtubules. May play a role in the regulation of lipogenesis (By similarity)., [UniProtKB]; Mid1ip1b has a close interaction with gamma-tubulin protein and modulates lumen opening of the neural tube, gut, intestine, and kidney of zebrafish., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6P955", "ec_number_list": [], "go_molecular_function": "GO:0140496 gamma-tubulin complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005874 microtubule", "go_biological_process": "GO:0072175 epithelial tube formation;GO:0061842 microtubule organizing center localization;GO:0046890 regulation of lipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q1LUV9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LUZ7-1", "uniprot_id": [ { "id": "Q1LUZ7_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LUZ7", "type": "external" } ], "mass": 137193.0, "length": 1261, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "hipk3b", "organism": "Zebrafish", "refseq_name": "homeodomain-interacting protein kinase 3", "refseq_ac": [ { "id": "NP_001073628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073628", "type": "external" } ], "gene_names_uniprotkb": "hipk3b; fd59e05; hm:zeh1150; si:dkey-261h15.1; wu:fd59e05; zeh1150", "gene_names_refseq": "fd59e05; hipk3b; hm:zeh1150; si:dkey-261h15.1; wu:fd59e05; zeh1150", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "homeodomain-interacting protein kinase 3", "tax_id": 7955, "disease": "Parkinson's disease (Disease Ontology:DOID:14330); depressive disorder (Disease Ontology:DOID:1596); cancer (Disease Ontology:DOID:162)", "pathway": " (dre:569156)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "11116087;20937081;26469318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588724.942054.1, SRR32588714.34872302.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505378, SAMEA3505380 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000018.1., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NCP8", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016605 PML body", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q1LUZ7-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LV46-1", "uniprot_id": [ { "id": "ABHEA_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LV46", "type": "external" } ], "mass": 29664.0, "length": 270, "protein_name": "Protein ABHD14A", "gene_name": "abhd14a", "organism": "Zebrafish", "refseq_name": "protein ABHD14A", "refseq_ac": [ { "id": "NP_996949", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996949", "type": "external" } ], "gene_names_uniprotkb": "abhd14a; si:ch211-231a1.1; zgc:85972", "gene_names_refseq": "abhd14a; zgc:85972", "protein_names_uniprotkb": "Protein ABHD14A; 3.-.-.-; Abhydrolase domain-containing protein 14A; Alpha/beta hydrolase domain-containing protein 14A", "protein_names_refseq": "abhydrolase domain-containing protein 14A; alpha/beta hydrolase domain-containing protein 14A; protein ABHD14A", "tax_id": 7955, "disease": "", "pathway": " (dre:404598)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC066291.1, GDQH01032032.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505378, SAMEA3505386 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1, EH433068.1 and EH459072.1. On Feb 2, 2016 this sequence version replaced NP_996949.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Possible role in granule neuron development., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q6NZ71", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1LV46-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LVK2-1", "uniprot_id": [ { "id": "Q1LVK2_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LVK2", "type": "external" } ], "mass": 14594.0, "length": 126, "protein_name": "DNA-directed RNA polymerase subunit", "gene_name": "polr2i", "organism": "Zebrafish", "refseq_name": "DNA-directed RNA polymerase II subunit RPB9", "refseq_ac": [ { "id": "NP_001006013", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006013", "type": "external" } ], "gene_names_uniprotkb": "polr2i; zgc:103515", "gene_names_refseq": "polr2i; zgc:103515", "protein_names_uniprotkb": "DNA-directed RNA polymerase subunit", "protein_names_refseq": "DNA-directed RNA polymerase II subunit RPB9; polymerase (RNA) II (DNA directed) polypeptide I", "tax_id": 7955, "disease": "", "pathway": " (dre:449992); (R-DRE-113418); (R-DRE-674695); (R-DRE-6781823); (R-DRE-6782135); (R-DRE-6782210); (R-DRE-6796648); (R-DRE-6803529); (R-DRE-6807505); (R-DRE-72086); (R-DRE-72163); (R-DRE-72165); (R-DRE-72203); (R-DRE-73776); (R-DRE-73779); (R-DRE-75953); (R-DRE-75955); (R-DRE-76042); (R-DRE-77075); (R-DRE-9018519); (R-DRE-9770562)", "pathway_count": 21, "publication_count": 2, "publication_id_list": "15520368;27189481", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: EH537652.1, GW713706.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505382, SAMEA3505383 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1 and EH547871.1. On or before May 22, 2009 this sequence version replaced NP_001122023.1, NP_001006013.1., [RefSeq]; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B0R0Q8", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005665 RNA polymerase II, core complex", "go_biological_process": "GO:0001193 maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0006283 transcription-coupled nucleotide-excision repair", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q1LVK2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LVM8-1", "uniprot_id": [ { "id": "Q1LVM8_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LVM8", "type": "external" } ], "mass": 50035.0, "length": 449, "protein_name": "Repulsive guidance molecule A", "gene_name": "rgma", "organism": "Zebrafish", "refseq_name": "repulsive guidance molecule A", "refseq_ac": [ { "id": "NP_001038476", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038476", "type": "external" } ], "gene_names_uniprotkb": "rgma; dlm; hfe2; id:ibd2030; rgmc; wu:fb72h09; zgc:110534", "gene_names_refseq": "dlm; hfe2; id:ibd2030; rgma; rgmc; wu:fb72h09; zgc:110534", "protein_names_uniprotkb": "Repulsive guidance molecule A", "protein_names_refseq": "RGM domain family, member A; dragon-like muscle; repulsive guidance molecule A; repulsive guidance molecule c; repulsive guidance molecule family member a", "tax_id": 7955, "disease": "multiple sclerosis (Disease Ontology:DOID:2377)", "pathway": " (dre:414272)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "11731487;14985445;17593421;19478994;21283739;27189481;28252024;31399534;32001375;33925390", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01032570.1, SRR32588722.15589803.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000018.1. On or before Apr 11, 2008 this sequence version replaced NP_001001726.1, XP_685194.1, XP_707831.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; We reveal that Rgma-Neo1 signaling controls neuroepithelial cel elongation independently of the establishment of apical junctional complexes and identify Rgma-induced Neo1 proteolytic cleavage as a key upstream signaling event, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8M1NA01", "ec_number_list": [], "go_molecular_function": "GO:0015026 coreceptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "GO:0030509 BMP signaling pathway;GO:0010604 positive regulation of macromolecule metabolic process;GO:0080090 regulation of primary metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q1LVM8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LVN1-1", "uniprot_id": [ { "id": "F174B_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LVN1", "type": "external" } ], "mass": 14877.0, "length": 133, "protein_name": "Membrane protein FAM174B", "gene_name": "Fam174b; fam174b", "organism": "Zebrafish", "refseq_name": "membrane protein FAM174B isoform 2 precursor", "refseq_ac": [ { "id": "NP_001096605", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096605", "type": "external" } ], "gene_names_uniprotkb": "Fam174b; fam174b; si:ch211-196l7.3", "gene_names_refseq": "fam174b; si:ch211-196l7.3", "protein_names_uniprotkb": "Membrane protein FAM174B", "protein_names_refseq": "membrane protein FAM174B isoform 2 precursor", "tax_id": 7955, "disease": "", "pathway": " (dre:798908)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "19478994;23594743;26469318", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC152510.1, CO933607.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC152510.1. On Sep 5, 2007 this sequence version replaced XP_001334608.1., [RefSeq]; Essential for Golgi structural integrity., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A7MD72", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q1LVN1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LVN8-1", "uniprot_id": [ { "id": "SELO1_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LVN8", "type": "external" } ], "mass": 77450.0, "length": 692, "protein_name": "Protein adenylyltransferase SelO-1, mitochondrial", "gene_name": "selenoo1", "organism": "Zebrafish", "refseq_name": "selenoprotein O1", "refseq_ac": [ { "id": "NP_001038336", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038336", "type": "external" } ], "gene_names_uniprotkb": "selenoo1; selo; si:ch211-15i6.2", "gene_names_refseq": "fd10b07; selenoo1; selenoo; selo; si:ch211-15i6.2; wu:fd10b07", "protein_names_uniprotkb": "Protein adenylyltransferase SelO-1, mitochondrial; 2.7.7.108; SelO; Selenoprotein O", "protein_names_refseq": "protein adenylyltransferase SelO-1, mitochondrial; selenoprotein O1; selenoprotein O", "tax_id": 7955, "disease": "", "pathway": " (dre:558648)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01000594.1, GFIL01034751.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505377 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from EH531320.1, EH495893.1, JBMGRA010000018.1, AI959437.1, EE689105.1, AI545086.1, EH522202.1 and AI959516.1. On Feb 2, 2010 this sequence version replaced NP_001038336.1. This gene encodes a selenoprotein containing the rare amino acid, selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs in vertebrates contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. The The exact function of this selenoprotein is not known, but it is thought to have redox activity. A paralog of this gene is found on chromosome 4 (GeneID:558542). [provided by RefSeq, Aug 2017]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr and Tyr residues of target proteins (AMPylation). May be a redox-active mitochondrial selenoprotein which interacts with a redox target protein., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.108", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.108", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0070733 AMPylase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1LVN8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LVQ2-1", "uniprot_id": [ { "id": "SH34A_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LVQ2", "type": "external" } ], "mass": 108453.0, "length": 965, "protein_name": "SH3 domain-binding protein 4-A", "gene_name": "sh3bp4a", "organism": "Zebrafish", "refseq_name": "SH3 domain-binding protein 4-A", "refseq_ac": [ { "id": "NP_001303259", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303259", "type": "external" } ], "gene_names_uniprotkb": "sh3bp4a; sh3bp4; si:dkey-110p14.1", "gene_names_refseq": "sh3bp4a; sh3bp4", "protein_names_uniprotkb": "SH3 domain-binding protein 4-A", "protein_names_refseq": "SH3 domain-binding protein 4-A; SH3-domain binding protein 4; src homology 3 binding protein 4", "tax_id": 7955, "disease": "", "pathway": " (R-DRE-9639288)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23594743", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01016868.1, GFIL01035151.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505378 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On Oct 15, 2015 this sequence version replaced XP_005161755.1., [RefSeq]; Possible role in regulating endocytosis of the transferrin receptor at the plasma membrane. Alternatively, may function as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4V977;Q76JU7", "ec_number_list": [], "go_molecular_function": "GO:0005092 GDP-dissociation inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005905 clathrin-coated pit;GO:0030136 clathrin-coated vesicle", "go_biological_process": "GO:0006897 endocytosis;GO:0008285 negative regulation of cell population proliferation;GO:0050790 regulation of catalytic activity;GO:0030308 negative regulation of cell growth;GO:0010508 positive regulation of autophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1LVQ2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LWC2-1", "uniprot_id": [ { "id": "T106B_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LWC2", "type": "external" } ], "mass": 29858.0, "length": 267, "protein_name": "Transmembrane protein 106B", "gene_name": "tmem106bb; tmem106b", "organism": "Zebrafish", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "tmem106bb; tmem106b; ch211-134n17.2; ch211-195l15.2; tmem106b; zgc:114147", "gene_names_refseq": "", "protein_names_uniprotkb": "Transmembrane protein 106B", "protein_names_refseq": "", "tax_id": 7955, "disease": "hypomyelinating leukodystrophy 16 (Disease Ontology:DOID:0070405)", "pathway": " (dre:566699)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "20526952;21356182;23594743;27189481;28252024;35886843;39120151", "class_list": "", "function": "In neurons, involved in the transport of late endosomes/lysosomes (By similarity). May be involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking (By similarity). May act as a molecular brake for retrograde transport of late endosomes/lysosomes, possibly via its interaction with MAP6 (By similarity). In motoneurons, may mediate the axonal transport of lysosomes and axonal sorting at the initial segment (By similarity). It remains unclear whether TMEM106B affects the transport of moving lysosomes in the anterograde or retrograde direction in neurites and whether it is particularly important in the sorting of lysosomes in axons or in dendrites (By similarity). In neurons, may also play a role in the regulation of lysosomal size and responsiveness to stress (By similarity). Required for proper lysosomal acidification (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "Q1LYK6", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0048813 dendrite morphogenesis;GO:0032418 lysosome localization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q1LWC2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LWC3-1", "uniprot_id": [ { "id": "Q1LWC3_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LWC3", "type": "external" } ], "mass": 28113.0, "length": 257, "protein_name": "Phosphatidylinositol-4,5-bisphosphate 4-phosphatase", "gene_name": "pip4p2", "organism": "Zebrafish", "refseq_name": "type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase", "refseq_ac": [ { "id": "NP_001038577", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038577", "type": "external" } ], "gene_names_uniprotkb": "pip4p2; si:ch211-134n17.1; tmem55a", "gene_names_refseq": "pip4p2; si:ch211-134n17.1; tmem55a", "protein_names_uniprotkb": "Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; 3.1.3.78", "protein_names_refseq": "transmembrane protein 55A; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase", "tax_id": 7955, "disease": "", "pathway": " (dre:566642)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "27189481;28252024", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01041245.1, CT681607.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000019.1. On Sep 1, 2006 this sequence version replaced XP_695012.1., [RefSeq]; Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P)., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N1TQ78", "ec_number_list": [ { "id": "3.1.3.78", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.78", "type": "external" } ], "go_molecular_function": "GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0030670 phagocytic vesicle membrane", "go_biological_process": "GO:0046856 phosphatidylinositol dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q1LWC3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LWH3-1", "uniprot_id": [ { "id": "Q1LWH3_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LWH3", "type": "external" } ], "mass": 119962.0, "length": 1074, "protein_name": "Membrane-bound transcription factor site-1 protease", "gene_name": "mbtps1", "organism": "Zebrafish", "refseq_name": "membrane-bound transcription factor site-1 protease precursor", "refseq_ac": [ { "id": "NP_954683", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954683", "type": "external" } ], "gene_names_uniprotkb": "mbtps1; goz1; s1p; wu:fe06e05", "gene_names_refseq": "goz1; mbtps1; s1p; wu:fe06e05", "protein_names_uniprotkb": "Membrane-bound transcription factor site-1 protease; 3.4.21.112; Endopeptidase S1P", "protein_names_refseq": "gonzo; goz; membrane-bound transcription factor protease, site 1; membrane-bound transcription factor site-1 protease precursor", "tax_id": 7955, "disease": "idiopathic scoliosis (Disease Ontology:DOID:0060250); spondyloepiphyseal dysplasia Kondo-Fu type (Disease Ontology:DOID:0112283)", "pathway": " (dre:326710); (R-DRE-381033); (R-DRE-381426); (R-DRE-8874211); (R-DRE-8957275)", "pathway_count": 5, "publication_count": 10, "publication_id_list": "14612568;15256591;19127516;21538441;21729877;27562099;28252024;32694732;32839180;34066767", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: AY261515.1, GDQH01000692.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1 and EB946210.1. On Jun 25, 2015 this sequence version replaced NP_954683.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Required for chondrocyte morphogenesis, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7XJA4;F1QAK2", "ec_number_list": [ { "id": "5.3.4.1", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.4.1", "type": "external" }, { "id": "3.4.24.81", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.81", "type": "external" }, { "id": "1.8.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.3.2", "type": "external" }, { "id": "3.1.1.98", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.98", "type": "external" }, { "id": "3.4.21.112", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.112", "type": "external" } ], "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0001889 liver development;GO:0006508 proteolysis;GO:0006629 lipid metabolic process;GO:0008203 cholesterol metabolic process;GO:0051216 cartilage development", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q1LWH3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000000001.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1LWJ1-1", "uniprot_id": [ { "id": "Q1LWJ1_DANRE", "url": "https://www.uniprot.org/uniprot/Q1LWJ1", "type": "external" } ], "mass": 31830.0, "length": 286, "protein_name": "Purine nucleoside phosphorylase", "gene_name": "pnp6", "organism": "Zebrafish", "refseq_name": "purine nucleoside phosphorylase 6", "refseq_ac": [ { "id": "NP_991218", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_991218", "type": "external" } ], "gene_names_uniprotkb": "pnp6; zgc:77182", "gene_names_refseq": "pnp6; zgc:77182", "protein_names_uniprotkb": "Purine nucleoside phosphorylase; 2.4.2.1; Inosine-guanosine phosphorylase", "protein_names_refseq": "purine nucleoside phosphorylase 6", "tax_id": 7955, "disease": "purine nucleoside phosphorylase deficiency (Disease Ontology:DOID:5813); purine-pyrimidine metabolic disorder (Disease Ontology:DOID:653)", "pathway": " (dre:402953)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15520368;20460180;28252024;28258112", "class_list": "", "function": "##Evidence-Data-START## Transcript exon combination :: BC065621.1, GDQQ01008676.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1 and CK028065.1. On Jun 6, 2009 this sequence version replaced NP_991218.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Preferentially acts on 6-oxopurine nucleosides including inosine and guanosine., [UniProtKB, UniProtKB]; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8N7V076", "ec_number_list": [ { "id": "3.5.4.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.4", "type": "external" }, { "id": "2.4.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.1", "type": "external" }, { "id": "2.4.2.28", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.28", "type": "external" } ], "go_molecular_function": "GO:0004731 purine-nucleoside phosphorylase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006166 purine ribonucleoside salvage", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q1LWJ1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000", "kg_view_protein": true } ]