[
    {
        "uniprot_canonical_ac": "E7FGC2-1",
        "uniprot_id": [
            {
                "id": "E7FGC2_DANRE",
                "url": "https://www.uniprot.org/uniprot/E7FGC2",
                "type": "external"
            }
        ],
        "mass": 145758.0,
        "length": 1289,
        "protein_name": "Structural maintenance of chromosomes protein",
        "gene_name": "smc4",
        "organism": "Zebrafish",
        "refseq_name": "structural maintenance of chromosomes protein 4",
        "refseq_ac": [
            {
                "id": "NP_775360",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775360",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "smc4; cb788; chunp6901; fb99b10; smc4l1; wu:fb99b10",
        "gene_names_refseq": "cb788; chunp6901; fb99b10; smc4l1; smc4; wu:fb99b10",
        "protein_names_uniprotkb": "Structural maintenance of chromosomes protein",
        "protein_names_refseq": "MC4 structural maintenance of chromosomes 4-like 1; structural maintenance of chromosomes protein 4",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:192332)",
        "pathway_count": 1,
        "publication_count": 8,
        "publication_id_list": "12006978;16109975;19723591;24198278;26469318;27156127;27189481;34434933",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: AY099521.1, SRR26395064.1693516.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505378, SAMEA3505382 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1, EB935660.1, EB930997.1, EH591853.1, EH586089.1, EH609354.1 and EH603521.1. On May 23, 2015 this sequence version replaced NP_775360.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8N1TUC6",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0000796 condensin complex",
        "go_biological_process": "GO:0051301 cell division;GO:0007076 mitotic chromosome condensation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.9,
        "record_id": "E7FGC2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E7FGK7-1",
        "uniprot_id": [
            {
                "id": "E7FGK7_DANRE",
                "url": "https://www.uniprot.org/uniprot/E7FGK7",
                "type": "external"
            }
        ],
        "mass": 35882.0,
        "length": 322,
        "protein_name": "Voltage-dependent calcium channel gamma-4 subunit",
        "gene_name": "cacng4b",
        "organism": "Zebrafish",
        "refseq_name": "calcium channel, voltage-dependent, gamma subunit 4b",
        "refseq_ac": [
            {
                "id": "NP_001315032",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315032",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cacng4b; cacng4",
        "gene_names_refseq": "cacng4b; cacng4",
        "protein_names_uniprotkb": "Voltage-dependent calcium channel gamma-4 subunit",
        "protein_names_refseq": "calcium channel, voltage-dependent, gamma subunit 4b",
        "tax_id": 7955,
        "disease": "acute myocardial infarction (Disease Ontology:DOID:9408)",
        "pathway": " (dre:794222)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "27189481;34329618",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.47273445.1, SRR26395062.683148.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476736 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On Jun 4, 2016 this sequence version replaced XP_001334133.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 1,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P4D7",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005245 voltage-gated calcium channel activity;GO:0016247 channel regulator activity",
        "go_cellular_component": "GO:0032281 AMPA glutamate receptor complex;GO:0005891 voltage-gated calcium channel complex;GO:0098839 postsynaptic density membrane",
        "go_biological_process": "GO:0051968 positive regulation of synaptic transmission, glutamatergic;GO:0019226 transmission of nerve impulse;GO:0098970 postsynaptic neurotransmitter receptor diffusion trapping",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "E7FGK7-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E7FGT8-1",
        "uniprot_id": [
            {
                "id": "E7FGT8_DANRE",
                "url": "https://www.uniprot.org/uniprot/E7FGT8",
                "type": "external"
            }
        ],
        "mass": 531568.0,
        "length": 4626,
        "protein_name": "Dynein axonemal heavy chain 10",
        "gene_name": "dnah10",
        "organism": "Zebrafish",
        "refseq_name": "dynein axonemal heavy chain 10",
        "refseq_ac": [
            {
                "id": "XP_009299843",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009299843",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "dnah10",
        "gene_names_refseq": "dnah10",
        "protein_names_uniprotkb": "Dynein axonemal heavy chain 10",
        "protein_names_refseq": "dynein axonemal heavy chain 10",
        "tax_id": 7955,
        "disease": "idiopathic scoliosis (Disease Ontology:DOID:0060250); spermatogenic failure (Disease Ontology:DOID:0111910); spermatogenic failure 56 (Disease Ontology:DOID:0112336); obesity (Disease Ontology:DOID:9970)",
        "pathway": " (dre:569992)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 3,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 3,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 4,
        "glyco_site_count": 3,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M3ASF8",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0008569 minus-end-directed microtubule motor activity;GO:0051959 dynein light intermediate chain binding;GO:0045505 dynein intermediate chain binding",
        "go_cellular_component": "GO:0005874 microtubule;GO:0030286 dynein complex;GO:0005858 axonemal dynein complex;GO:0097729 9+2 motile cilium",
        "go_biological_process": "GO:0060294 cilium movement involved in cell motility;GO:0007368 determination of left/right symmetry;GO:0003341 cilium movement",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E7FGT8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.000100.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E7FH41-1",
        "uniprot_id": [
            {
                "id": "E7FH41_DANRE",
                "url": "https://www.uniprot.org/uniprot/E7FH41",
                "type": "external"
            }
        ],
        "mass": 71085.0,
        "length": 638,
        "protein_name": "RING-type E3 ubiquitin transferase",
        "gene_name": "rlim",
        "organism": "Zebrafish",
        "refseq_name": "E3 ubiquitin-protein ligase RLIM",
        "refseq_ac": [
            {
                "id": "XP_009306042",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009306042",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "rlim",
        "gene_names_refseq": "rlim",
        "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27",
        "protein_names_refseq": "E3 ubiquitin-protein ligase RLIM",
        "tax_id": 7955,
        "disease": "Tonne-Kalscheuer syndrome (Disease Ontology:DOID:0112042)",
        "pathway": " (dre:562487);  (R-DRE-983168)",
        "pathway_count": 2,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
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        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 1,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M3BEZ3",
        "ec_number_list": [
            {
                "id": "2.3.2.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.-",
                "type": "external"
            },
            {
                "id": "2.3.2.27",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27",
                "type": "external"
            },
            {
                "id": "3.6.4.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-",
                "type": "external"
            },
            {
                "id": "2.3.2.34",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.34",
                "type": "external"
            },
            {
                "id": "2.3.2.26",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.26",
                "type": "external"
            },
            {
                "id": "6.2.1.45",
                "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.45",
                "type": "external"
            },
            {
                "id": "2.3.2.31",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31",
                "type": "external"
            },
            {
                "id": "2.3.2.23",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23",
                "type": "external"
            },
            {
                "id": "3.4.19.12",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12",
                "type": "external"
            },
            {
                "id": "2.3.2.25",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.25",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0017015 regulation of transforming growth factor beta receptor signaling pathway;GO:0060816 random inactivation of X chromosome;GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E7FH41-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E7FH61-1",
        "uniprot_id": [
            {
                "id": "CNDG2_DANRE",
                "url": "https://www.uniprot.org/uniprot/E7FH61",
                "type": "external"
            }
        ],
        "mass": 129093.0,
        "length": 1140,
        "protein_name": "Condensin-2 complex subunit G2",
        "gene_name": "ncapg2",
        "organism": "Zebrafish",
        "refseq_name": "condensin-2 complex subunit G2",
        "refseq_ac": [
            {
                "id": "NP_001082961",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082961",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ncapg2; CAP-G2; id:ibd2775; zgc:162881",
        "gene_names_refseq": "CAP-G2; id:ibd2775; ncapg2; zgc:162881",
        "protein_names_uniprotkb": "Condensin-2 complex subunit G2; CAP-G2; Chromosome-associated protein G2; Non-SMC condensin II complex subunit G2",
        "protein_names_refseq": "chromosome-associated protein G2; condensin-2 complex subunit G2; leucine zipper protein 5",
        "tax_id": 7955,
        "disease": "autosomal recessive disease (Disease Ontology:DOID:0050737)",
        "pathway": " (dre:100037337);  (R-DRE-2299718)",
        "pathway_count": 2,
        "publication_count": 2,
        "publication_id_list": "23594743;30609410",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01027697.1, GDQH01010576.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898400, SAMEA898401 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Jun 25, 2025 this sequence version replaced NP_001082961.3. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript was available for the full length of the gene. The genomic coordinates used for the transcript record were based on transcript and protein alignments, including frog NP_001086462.1, mouse NP_598523.3, human NP_060230.5, and RNA-Seq data., [RefSeq]; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis (By similarity). Plays a role in the embryonic development of the head and kidney structures (PubMed:30609410)., [UniProtKB, UniProtKB, PubMed]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 1,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "F8W2J6",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005634 nucleus;GO:0000796 condensin complex",
        "go_biological_process": "GO:0051301 cell division;GO:0030261 chromosome condensation;GO:0000070 mitotic sister chromatid segregation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "E7FH61-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E7FH62-1",
        "uniprot_id": [
            {
                "id": "E7FH62_DANRE",
                "url": "https://www.uniprot.org/uniprot/E7FH62",
                "type": "external"
            }
        ],
        "mass": 156746.0,
        "length": 1400,
        "protein_name": "Glutamate receptor",
        "gene_name": "grin2ca",
        "organism": "Zebrafish",
        "refseq_name": "glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca precursor",
        "refseq_ac": [
            {
                "id": "NP_001352716",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352716",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "grin2ca; NR2C.1; ZN2C.1; grin2c",
        "gene_names_refseq": "NR2C.1; ZN2C.1; grin2ca; grin2c",
        "protein_names_uniprotkb": "Glutamate receptor",
        "protein_names_refseq": "glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca precursor; glutamate receptor, ionotropic, N-methyl D-aspartate 2C",
        "tax_id": 7955,
        "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037); epilepsy (Disease Ontology:DOID:1826)",
        "pathway": " (dre:100003342)",
        "pathway_count": 1,
        "publication_count": 6,
        "publication_id_list": "16123982;17640376;19500364;25602300;27189481;28252024",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588719.685589.1, SRR32588727.2132850.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On Sep 12, 2018 this sequence version replaced XP_002661175.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 2,
        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1RQV2;F6PCG7",
        "ec_number_list": [
            {
                "id": "2.7.11.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
                "type": "external"
            },
            {
                "id": "1.5.1.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.2",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential;GO:0004972 NMDA glutamate receptor activity",
        "go_cellular_component": "GO:0017146 NMDA selective glutamate receptor complex;GO:0005886 plasma membrane;GO:0098839 postsynaptic density membrane",
        "go_biological_process": "GO:0060079 excitatory postsynaptic potential;GO:0035249 synaptic transmission, glutamatergic;GO:0098655 monoatomic cation transmembrane transport;GO:0060291 long-term synaptic potentiation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.7,
        "record_id": "E7FH62-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E9QB52-1",
        "uniprot_id": [
            {
                "id": "E9QB52_DANRE",
                "url": "https://www.uniprot.org/uniprot/E9QB52",
                "type": "external"
            }
        ],
        "mass": 74105.0,
        "length": 666,
        "protein_name": "tRNA (carboxymethyluridine(34)-5-O)-methyltransferase",
        "gene_name": "alkbh8",
        "organism": "Zebrafish",
        "refseq_name": "tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ALKBH8 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009290865",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290865",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "alkbh8",
        "gene_names_refseq": "alkbh8",
        "protein_names_uniprotkb": "tRNA (carboxymethyluridine(34)-5-O)-methyltransferase; 2.1.1.229; Alkylated DNA repair protein alkB homolog 8; S-adenosyl-L-methionine-dependent tRNA methyltransferase ALKBH8",
        "protein_names_refseq": "tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ALKBH8 isoform X1",
        "tax_id": 7955,
        "disease": "autosomal recessive intellectual developmental disorder 71 (Disease Ontology:DOID:0081232)",
        "pathway": " (dre:556362)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S)-methoxycarbonylhydroxymethyluridine; has a preference for tRNA(Gly). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 1,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M3ATS0",
        "ec_number_list": [
            {
                "id": "2.1.1.229",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.229",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0046872 metal ion binding;GO:0000049 tRNA binding;GO:0008757 S-adenosylmethionine-dependent methyltransferase activity;GO:0106335 tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0002098 tRNA wobble uridine modification;GO:0030488 tRNA methylation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E9QB52-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E9QC42-1",
        "uniprot_id": [
            {
                "id": "E9QC42_DANRE",
                "url": "https://www.uniprot.org/uniprot/E9QC42",
                "type": "external"
            }
        ],
        "mass": 24781.0,
        "length": 220,
        "protein_name": "Vesicle-associated membrane protein 7",
        "gene_name": "sybl1",
        "organism": "Zebrafish",
        "refseq_name": "vesicle-associated membrane protein 7",
        "refseq_ac": [
            {
                "id": "NP_001429129",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429129",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "sybl1; zgc:56506",
        "gene_names_refseq": "sybl1; zgc:56506",
        "protein_names_uniprotkb": "Vesicle-associated membrane protein 7; Synaptobrevin-like protein 1",
        "protein_names_refseq": "vesicle-associated membrane protein 7",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (R-DRE-199992);  (R-DRE-432720);  (R-DRE-8856825)",
        "pathway_count": 3,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01005489.1, GDQQ01005166.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Jul 29, 2025 this sequence version replaced XP_005157192.1., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M2B385",
        "ec_number_list": [],
        "go_molecular_function": "GO:0000149 SNARE binding;GO:0005484 SNAP receptor activity",
        "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0045202 synapse;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:0030658 transport vesicle membrane",
        "go_biological_process": "GO:0015031 protein transport;GO:0008333 endosome to lysosome transport;GO:0006887 exocytosis;GO:0006906 vesicle fusion",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E9QC42-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E9QCD3-1",
        "uniprot_id": [
            {
                "id": "ZDH14_DANRE",
                "url": "https://www.uniprot.org/uniprot/E9QCD3",
                "type": "external"
            }
        ],
        "mass": 56393.0,
        "length": 513,
        "protein_name": "Palmitoyltransferase ZDHHC14",
        "gene_name": "zdhhc14",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "zdhhc14; DHHC-14; si:ch211-199l3.1",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Palmitoyltransferase ZDHHC14; 2.3.1.225; DHHC domain-containing cysteine-rich protein 14; DHHC-14; Zinc finger DHHC domain-containing protein 14",
        "protein_names_refseq": "",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 3,
        "publication_id_list": "23594743;26056731;27235108",
        "class_list": "",
        "function": "Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "2.3.1.225",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.225",
                "type": "external"
            },
            {
                "id": "2.3.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0019706 protein-cysteine S-palmitoyltransferase activity",
        "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0006612 protein targeting to membrane;GO:0018230 peptidyl-L-cysteine S-palmitoylation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.4,
        "record_id": "E9QCD3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000100.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E9QFU8-1",
        "uniprot_id": [
            {
                "id": "E9QFU8_DANRE",
                "url": "https://www.uniprot.org/uniprot/E9QFU8",
                "type": "external"
            }
        ],
        "mass": 43515.0,
        "length": 391,
        "protein_name": "Branched-chain-amino-acid aminotransferase",
        "gene_name": "bcat2",
        "organism": "Zebrafish",
        "refseq_name": "branched-chain-amino-acid aminotransferase, mitochondrial isoform 2",
        "refseq_ac": [
            {
                "id": "NP_001296456",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001296456",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "bcat2; fb37h12; wu:fb37h12; zgc:91919",
        "gene_names_refseq": "bcat2; fb37h12; wu:fb37h12; zgc:91919",
        "protein_names_uniprotkb": "Branched-chain-amino-acid aminotransferase; 2.6.1.42",
        "protein_names_refseq": "branched chain aminotransferase 2, mitochondrial; branched-chain-amino-acid aminotransferase, mitochondrial isoform 2",
        "tax_id": 7955,
        "disease": "hypervalinemia and hyperleucine-isoleucinemia (Disease Ontology:DOID:0060950); amino acid metabolic disorder (Disease Ontology:DOID:9252); maple syrup urine disease (Disease Ontology:DOID:9269)",
        "pathway": " (dre:436949);  (R-DRE-70895)",
        "pathway_count": 2,
        "publication_count": 10,
        "publication_id_list": "19850031;20528263;22046393;22302940;26469318;28252024;32710562;32720689;36408747;37305084",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395015.1931859.1, SRR26395017.405116.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505373 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On Jun 10, 2015 this sequence version replaced XP_005163998.1. Transcript Variant: This variant (2) uses an alternate splice junction in the 5' end of the coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. Branched chain amino acid catabolism plays a role in adipocyte differentiation by providing lipogenic acetyl-CoA pools in differentiated adipocytes. Mechanistically, acetyl-CoA derived from branched chain amino acid catabolism is used by EP300/p300 to acetylate and inhibit PRDM16, thereby preventing adipose tissue browning. May also function as a transporter of branched chain alpha-keto acids., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 3,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P782",
        "ec_number_list": [
            {
                "id": "2.6.1.42",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.42",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004084 branched-chain-amino-acid transaminase activity;GO:0008483 transaminase activity",
        "go_cellular_component": "GO:0005739 mitochondrion",
        "go_biological_process": "GO:0006629 lipid metabolic process;GO:0009098 L-leucine biosynthetic process;GO:0009099 L-valine biosynthetic process;GO:0008652 amino acid biosynthetic process;GO:0009082 branched-chain amino acid biosynthetic process",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "E9QFU8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E9QCY4-1",
        "uniprot_id": [
            {
                "id": "E9QCY4_DANRE",
                "url": "https://www.uniprot.org/uniprot/E9QCY4",
                "type": "external"
            }
        ],
        "mass": 8949.0,
        "length": 75,
        "protein_name": "Nuclear protein 1b",
        "gene_name": "nupr1b",
        "organism": "Zebrafish",
        "refseq_name": "nuclear protein 1b",
        "refseq_ac": [
            {
                "id": "NP_001268851",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001268851",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "nupr1b; fd46g12; nupr1; wu:fd46g12",
        "gene_names_refseq": "fd46g12; nupr1b; nupr1; wu:fd46g12",
        "protein_names_uniprotkb": "Nuclear protein 1b",
        "protein_names_refseq": "nuclear protein 1b; nuclear protein 1; p8",
        "tax_id": 7955,
        "disease": "Sertoli cell-only syndrome (Disease Ontology:DOID:0050457)",
        "pathway": " (dre:799637)",
        "pathway_count": 1,
        "publication_count": 5,
        "publication_id_list": "16631158;19560542;20036747;21052758;27189481",
        "class_list": "",
        "function": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH439701.1, EH488235.1 and BI979944.1. On Aug 31, 2013 this sequence version replaced XP_005163890.1., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 1,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P0S4",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0008285 negative regulation of cell population proliferation;GO:0071502 cellular response to temperature stimulus;GO:0009267 cellular response to starvation;GO:0045786 negative regulation of cell cycle",
        "synthesized_glycan_count": 0,
        "hit_score": 0.6,
        "record_id": "E9QCY4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E9QD66-1",
        "uniprot_id": [
            {
                "id": "E9QD66_DANRE",
                "url": "https://www.uniprot.org/uniprot/E9QD66",
                "type": "external"
            }
        ],
        "mass": 70749.0,
        "length": 625,
        "protein_name": "tRNA (uracil-O(2)-)-methyltransferase",
        "gene_name": "trmt44",
        "organism": "Zebrafish",
        "refseq_name": "probable tRNA (uracil-O(2)-)-methyltransferase",
        "refseq_ac": [
            {
                "id": "NP_001006086",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006086",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "trmt44; mettl19; zgc:101657",
        "gene_names_refseq": "mettl19; trmt44; zgc:101657",
        "protein_names_uniprotkb": "tRNA (uracil-O(2)-)-methyltransferase; 2.1.1.211",
        "protein_names_refseq": "methyltransferase like 19; probable tRNA (uracil-O(2)-)-methyltransferase",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:450066)",
        "pathway_count": 1,
        "publication_count": 3,
        "publication_id_list": "26469318;27189481;32784920",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01042032.1, GDQQ01051279.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505378, SAMEA4476730 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Aug 3, 2010 this sequence version replaced NP_001006086.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1N2X3",
        "ec_number_list": [
            {
                "id": "2.1.1.211",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.211",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016300 tRNA (uridine) methyltransferase activity;GO:0141101 tRNA(Ser) (uridine(44)-2'-O-)-methyltransferase activity",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0030488 tRNA methylation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.4,
        "record_id": "E9QD66-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E9QDI1-1",
        "uniprot_id": [
            {
                "id": "E9QDI1_DANRE",
                "url": "https://www.uniprot.org/uniprot/E9QDI1",
                "type": "external"
            }
        ],
        "mass": 9856.0,
        "length": 85,
        "protein_name": "Apolipoprotein C-I isoform 1 precursor",
        "gene_name": "apoc1",
        "organism": "Zebrafish",
        "refseq_name": "apolipoprotein C-I isoform 1 precursor",
        "refseq_ac": [
            {
                "id": "NP_001278815",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001278815",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "apoc1; apoc1l; fb58g10; wu:fb58g10",
        "gene_names_refseq": "apoc1l; apoc1; fb58g10; wu:fb58g10",
        "protein_names_uniprotkb": "Apolipoprotein C-I isoform 1 precursor",
        "protein_names_refseq": "apolipoprotein C-I isoform 1 precursor; apolipoprotein C-I like",
        "tax_id": 7955,
        "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); gastric adenocarcinoma (Disease Ontology:DOID:3717); hepatocellular carcinoma (Disease Ontology:DOID:684); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)",
        "pathway": " (dre:570638)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "16631158;18958591;23349717;24112639;24203452;33174840;34625548;34878094;35151729;38598053",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: CN321250.1, BC162528.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH489275.1, BC162528.1 and CN321250.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1). Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 6,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P660",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005504 fatty acid binding;GO:0004859 phospholipase inhibitor activity",
        "go_cellular_component": "GO:0034364 high-density lipoprotein particle;GO:0034361 very-low-density lipoprotein particle;GO:0005576 extracellular region",
        "go_biological_process": "GO:0006641 triglyceride metabolic process;GO:0006869 lipid transport;GO:0042157 lipoprotein metabolic process;GO:0050995 negative regulation of lipid catabolic process;GO:0032375 negative regulation of cholesterol transport",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "E9QDI1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E9QE29-1",
        "uniprot_id": [
            {
                "id": "E9QE29_DANRE",
                "url": "https://www.uniprot.org/uniprot/E9QE29",
                "type": "external"
            }
        ],
        "mass": 47920.0,
        "length": 421,
        "protein_name": "Stress-activated protein kinase JNK",
        "gene_name": "mapk9",
        "organism": "Zebrafish",
        "refseq_name": "mitogen-activated protein kinase 9",
        "refseq_ac": [
            {
                "id": "XP_001919688",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001919688",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mapk9",
        "gene_names_refseq": "mapk9",
        "protein_names_uniprotkb": "Stress-activated protein kinase JNK; 2.7.11.24",
        "protein_names_refseq": "mitogen-activated protein kinase 9",
        "tax_id": 7955,
        "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); pancreatic adenocarcinoma (Disease Ontology:DOID:4074); colorectal cancer (Disease Ontology:DOID:9256); type 2 diabetes mellitus (Disease Ontology:DOID:9352)",
        "pathway": " (dre:100149273);  (R-DRE-2559580);  (R-DRE-2871796);  (R-DRE-450321);  (R-DRE-450341)",
        "pathway_count": 5,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. May play a role in the regulation of the circadian clock., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 4,
        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1QUP6",
        "ec_number_list": [
            {
                "id": "2.7.11.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
                "type": "external"
            },
            {
                "id": "2.7.11.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13",
                "type": "external"
            },
            {
                "id": "2.7.11.25",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25",
                "type": "external"
            },
            {
                "id": "2.7.10.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1",
                "type": "external"
            },
            {
                "id": "2.7.11.22",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22",
                "type": "external"
            },
            {
                "id": "2.7.11.21",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21",
                "type": "external"
            },
            {
                "id": "2.7.11.17",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17",
                "type": "external"
            },
            {
                "id": "2.7.12.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1",
                "type": "external"
            },
            {
                "id": "2.7.12.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2",
                "type": "external"
            },
            {
                "id": "2.7.11.24",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24",
                "type": "external"
            },
            {
                "id": "2.7.10.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2",
                "type": "external"
            },
            {
                "id": "2.7.11.23",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23",
                "type": "external"
            },
            {
                "id": "2.7.1.150",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150",
                "type": "external"
            },
            {
                "id": "2.7.11.12",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12",
                "type": "external"
            },
            {
                "id": "2.7.11.39",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39",
                "type": "external"
            },
            {
                "id": "2.7.11.11",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11",
                "type": "external"
            },
            {
                "id": "2.7.1.153",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153",
                "type": "external"
            },
            {
                "id": "2.7.1.137",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137",
                "type": "external"
            },
            {
                "id": "2.7.1.154",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154",
                "type": "external"
            },
            {
                "id": "2.7.11.26",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26",
                "type": "external"
            },
            {
                "id": "2.7.11.31",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0004705 JUN kinase activity;GO:0106310 protein serine kinase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0007254 JNK cascade;GO:0048511 rhythmic process;GO:0060027 convergent extension involved in gastrulation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E9QE29-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E9QE31-1",
        "uniprot_id": [
            {
                "id": "E9QE31_DANRE",
                "url": "https://www.uniprot.org/uniprot/E9QE31",
                "type": "external"
            }
        ],
        "mass": 83174.0,
        "length": 723,
        "protein_name": "Calpain-3",
        "gene_name": "capn3b",
        "organism": "Zebrafish",
        "refseq_name": "calpain-3b",
        "refseq_ac": [
            {
                "id": "NP_001230250",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230250",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "capn3b; si:dkey-12h9.9",
        "gene_names_refseq": "capn3b; si:dkey-12h9.9",
        "protein_names_uniprotkb": "Calpain-3; 3.4.22.54",
        "protein_names_refseq": "calpain-3b",
        "tax_id": 7955,
        "disease": "autosomal dominant limb-girdle muscular dystrophy (Disease Ontology:DOID:0110273); autosomal recessive limb-girdle muscular dystrophy type 2A (Disease Ontology:DOID:0110275); muscular dystrophy (Disease Ontology:DOID:9884)",
        "pathway": " (dre:100034405);  (R-DRE-1474228)",
        "pathway_count": 2,
        "publication_count": 10,
        "publication_id_list": "23357851;26908177;27189481;29666124;29751158;32588143;35878425;36833417;37013516;39036955",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01003015.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On Aug 11, 2011 this sequence version replaced XP_003200752.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; An 86 amino acids motif in CAPN3 is essential for formation of the nucleolus-localized Def-CAPN3 complex., [RefSeq, PubMed]; Calcium-regulated non-lysosomal thiol-protease., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
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        "reported_s_glycosites": 0,
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        "reported_phosphosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P227",
        "ec_number_list": [
            {
                "id": "3.4.22.54",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.54",
                "type": "external"
            },
            {
                "id": "3.4.22.17",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.17",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004198 calcium-dependent cysteine-type endopeptidase activity;GO:0005509 calcium ion binding;GO:0008233 peptidase activity",
        "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006508 proteolysis;GO:0043066 negative regulation of apoptotic process;GO:0030163 protein catabolic process;GO:1990092 calcium-dependent self proteolysis",
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        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "E9QE70_DANRE",
                "url": "https://www.uniprot.org/uniprot/E9QE70",
                "type": "external"
            }
        ],
        "mass": 50951.0,
        "length": 453,
        "protein_name": "Gamma-aminobutyric acid receptor subunit alpha-5",
        "gene_name": "gabra5",
        "organism": "Zebrafish",
        "refseq_name": "gamma-aminobutyric acid receptor subunit alpha-5",
        "refseq_ac": [
            {
                "id": "XP_005166139",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166139",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "gabra5",
        "gene_names_refseq": "gabra5",
        "protein_names_uniprotkb": "Gamma-aminobutyric acid receptor subunit alpha-5",
        "protein_names_refseq": "gamma-aminobutyric acid receptor subunit alpha-5",
        "tax_id": 7955,
        "disease": "developmental and epileptic encephalopathy 79 (Disease Ontology:DOID:0112215); autistic disorder (Disease Ontology:DOID:12849); depressive disorder (Disease Ontology:DOID:1596); bipolar disorder (Disease Ontology:DOID:3312)",
        "pathway": " (dre:799124);  (R-DRE-977443)",
        "pathway_count": 2,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "A0A8M9QG82;F1QZ29",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004890 GABA-A receptor activity;GO:0022851 GABA-gated chloride ion channel activity",
        "go_cellular_component": "GO:0045211 postsynaptic membrane;GO:0098794 postsynapse;GO:0034707 chloride channel complex;GO:0032590 dendrite membrane;GO:1902711 GABA-A receptor complex",
        "go_biological_process": "GO:0007214 gamma-aminobutyric acid signaling pathway;GO:1902476 chloride transmembrane transport;GO:0051932 synaptic transmission, GABAergic;GO:1904862 inhibitory synapse assembly",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E9QE70-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E9QEL7-1",
        "uniprot_id": [
            {
                "id": "E9QEL7_DANRE",
                "url": "https://www.uniprot.org/uniprot/E9QEL7",
                "type": "external"
            }
        ],
        "mass": 87376.0,
        "length": 792,
        "protein_name": "Cadherin-15 precursor",
        "gene_name": "cdh15",
        "organism": "Zebrafish",
        "refseq_name": "cadherin-15 precursor",
        "refseq_ac": [
            {
                "id": "NP_997771",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997771",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cdh15; fb48f12; wu:fb48f12",
        "gene_names_refseq": "cdh15; fb48f12; wu:fb48f12",
        "protein_names_uniprotkb": "Cadherin-15 precursor",
        "protein_names_refseq": "M cadherin; cadherin 15, M-cadherin (myotubule); cadherin-15 precursor",
        "tax_id": 7955,
        "disease": "autosomal dominant intellectual developmental disorder 3 (Disease Ontology:DOID:0070033)",
        "pathway": " (dre:565617);  (R-DRE-418990);  (R-DRE-525793)",
        "pathway_count": 3,
        "publication_count": 10,
        "publication_id_list": "14667409;16109975;17849437;22624717;22655075;27189481;28080960;28271061;33004519;33951474",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC163462.1, AY443033.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505392, SAMEA4476730 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Jun 25, 2025 this sequence version replaced NP_997771.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Cadherins are calcium-dependent cell adhesion proteins., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "A0A8M1PFA3",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005509 calcium ion binding;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005912 adherens junction;GO:0016342 catenin complex",
        "go_biological_process": "GO:0016477 cell migration;GO:0001764 neuron migration;GO:0000902 cell morphogenesis;GO:0007043 cell-cell junction assembly;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "E9QEL7-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E9QFW9-1",
        "uniprot_id": [
            {
                "id": "E9QFW9_DANRE",
                "url": "https://www.uniprot.org/uniprot/E9QFW9",
                "type": "external"
            }
        ],
        "mass": 28285.0,
        "length": 248,
        "protein_name": "Golgi SNAP receptor complex member 1",
        "gene_name": "gosr1",
        "organism": "Zebrafish",
        "refseq_name": "Golgi SNAP receptor complex member 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005157622",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157622",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "gosr1; zgc:112064",
        "gene_names_refseq": "gosr1; zgc:112064",
        "protein_names_uniprotkb": "Golgi SNAP receptor complex member 1",
        "protein_names_refseq": "Golgi SNAP receptor complex member 1 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (R-DRE-6807878);  (R-DRE-6811438)",
        "pathway_count": 2,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M2B4E0",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005484 SNAP receptor activity",
        "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005797 Golgi medial cisterna;GO:0005801 cis-Golgi network;GO:0031201 SNARE complex",
        "go_biological_process": "GO:0015031 protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006906 vesicle fusion;GO:0048219 inter-Golgi cisterna vesicle-mediated transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E9QFW9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E9QGX9-1",
        "uniprot_id": [
            {
                "id": "E9QGX9_DANRE",
                "url": "https://www.uniprot.org/uniprot/E9QGX9",
                "type": "external"
            }
        ],
        "mass": 63725.0,
        "length": 559,
        "protein_name": "Atlastin-1",
        "gene_name": "atl1",
        "organism": "Zebrafish",
        "refseq_name": "atlastin-1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005157066",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157066",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "atl1; fj46c01; spg3a; wu:fj46c01",
        "gene_names_refseq": "atl1; fj46c01; spg3a; wu:fj46c01",
        "protein_names_uniprotkb": "Atlastin-1",
        "protein_names_refseq": "atlastin-1 isoform X1",
        "tax_id": 7955,
        "disease": "hereditary sensory neuropathy type 1D (Disease Ontology:DOID:0070156); hereditary spastic paraplegia 3A (Disease Ontology:DOID:0110791)",
        "pathway": " (dre:571909)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "20935645;25534026;26469318;26744324;27189481;28252024;29021367;30082270;31791229;32315314",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Atlastin-1 (ATL1) is a membrane-anchored GTPase that mediates the GTP-dependent fusion of endoplasmic reticulum (ER) membranes, maintaining the continuous ER network. It facilitates the formation of three-way junctions where ER tubules intersect. Two atlastin-1 on neighboring ER tubules bind GTP and form loose homodimers through the GB1/RHD3-type G domains and 3HB regions. Upon GTP hydrolysis, the 3HB regions tighten, pulling the membranes together to drive their fusion. After fusion, the homodimer disassembles upon release of inorganic phosphate (Pi). Subsequently, GDP dissociates, resetting the monomers to a conformation ready for a new fusion cycle. May also regulate more or less directly Golgi biogenesis. Indirectly regulates axonal development., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M2B377",
        "ec_number_list": [
            {
                "id": "3.6.5.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2",
                "type": "external"
            },
            {
                "id": "3.6.5.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3",
                "type": "external"
            },
            {
                "id": "3.6.5.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5",
                "type": "external"
            },
            {
                "id": "3.6.1.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5",
                "type": "external"
            },
            {
                "id": "3.6.5.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-",
                "type": "external"
            },
            {
                "id": "3.6.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-",
                "type": "external"
            },
            {
                "id": "3.6.5.4",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding",
        "go_cellular_component": "GO:0000139 Golgi membrane;GO:0030424 axon;GO:0005789 endoplasmic reticulum membrane;GO:0005770 late endosome",
        "go_biological_process": "GO:0051260 protein homooligomerization;GO:0030514 negative regulation of BMP signaling pathway;GO:0007411 axon guidance;GO:0048263 determination of dorsal identity;GO:0007029 endoplasmic reticulum organization",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "E9QGX9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E9QH56-1",
        "uniprot_id": [
            {
                "id": "E9QH56_DANRE",
                "url": "https://www.uniprot.org/uniprot/E9QH56",
                "type": "external"
            }
        ],
        "mass": 30891.0,
        "length": 271,
        "protein_name": "Nicotinamide-nucleotide adenylyltransferase",
        "gene_name": "nmnat1",
        "organism": "Zebrafish",
        "refseq_name": "nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1",
        "refseq_ac": [
            {
                "id": "NP_001315257",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315257",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "nmnat1; id:ibd5068; im:7144541; zgc:110243",
        "gene_names_refseq": "id:ibd5068; im:7144541; nmnat1; zgc:110243",
        "protein_names_uniprotkb": "Nicotinamide-nucleotide adenylyltransferase; 2.7.7.18; 2.7.7.1",
        "protein_names_refseq": "nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1",
        "tax_id": 7955,
        "disease": "Leber congenital amaurosis 9 (Disease Ontology:DOID:0110005); spondyloepiphyseal dysplasia, sensorineural hearing loss, intellectual developmental disorder, and Leber congenital amaurosis (Disease Ontology:DOID:0112290); sciatic neuropathy (Disease Ontology:DOID:11446); neurodegenerative disease (Disease Ontology:DOID:1289); retinal degeneration (Disease Ontology:DOID:8466)",
        "pathway": " (dre:550322);  (R-DRE-196807)",
        "pathway_count": 2,
        "publication_count": 6,
        "publication_id_list": "11731487;18335061;22421047;24045113;26618989;34903892",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: EH495187.1, SRR32588733.2307419.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505373, SAMEA4476750 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1, EH495187.1 and CK016190.1. On Jun 13, 2016 this sequence version replaced XP_005162309.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 5,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1P9R7",
        "ec_number_list": [
            {
                "id": "2.7.7.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.1",
                "type": "external"
            },
            {
                "id": "2.7.7.18",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.18",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0004515 nicotinate-nucleotide adenylyltransferase activity;GO:0000309 nicotinamide-nucleotide adenylyltransferase activity",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0034355 NAD+ biosynthetic process via the salvage pathway",
        "synthesized_glycan_count": 0,
        "hit_score": 0.7,
        "record_id": "E9QH56-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E9QHW0-1",
        "uniprot_id": [
            {
                "id": "E9QHW0_DANRE",
                "url": "https://www.uniprot.org/uniprot/E9QHW0",
                "type": "external"
            }
        ],
        "mass": 43618.0,
        "length": 379,
        "protein_name": "Transforming growth factor beta",
        "gene_name": "tgfb1b",
        "organism": "Zebrafish",
        "refseq_name": "transforming growth factor beta-1 proprotein",
        "refseq_ac": [
            {
                "id": "XP_692338",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692338",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tgfb1b",
        "gene_names_refseq": "tgfb1b",
        "protein_names_uniprotkb": "Transforming growth factor beta",
        "protein_names_refseq": "transforming growth factor beta-1 proprotein",
        "tax_id": 7955,
        "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589); chorioamnionitis (Disease Ontology:DOID:0050697); atrial fibrillation (Disease Ontology:DOID:0060224); Camurati-Engelmann disease 1 (Disease Ontology:DOID:0061229); prostate cancer (Disease Ontology:DOID:10283); berylliosis (Disease Ontology:DOID:10322); hypertension (Disease Ontology:DOID:10763); sickle cell anemia (Disease Ontology:DOID:10923); anogenital venereal wart (Disease Ontology:DOID:11168); chlamydia (Disease Ontology:DOID:11263); heart disease (Disease Ontology:DOID:114); factor VIII deficiency (Disease Ontology:DOID:12134); vitiligo (Disease Ontology:DOID:12306); aplastic anemia (Disease Ontology:DOID:12449); hereditary hemorrhagic telangiectasia (Disease Ontology:DOID:1270); Sjogren's syndrome (Disease Ontology:DOID:12894); uveitis (Disease Ontology:DOID:13141); Behcet's disease (Disease Ontology:DOID:13241); Ehlers-Danlos syndrome (Disease Ontology:DOID:13359); pulmonary sarcoidosis (Disease Ontology:DOID:13406); biliary atresia (Disease Ontology:DOID:13608); eosinophilic esophagitis (Disease Ontology:DOID:13922); cystic fibrosis (Disease Ontology:DOID:1485); colon carcinoma (Disease Ontology:DOID:1520); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); osteochondrodysplasia (Disease Ontology:DOID:2256); colon adenocarcinoma (Disease Ontology:DOID:234); arteriosclerosis (Disease Ontology:DOID:2349); asthma (Disease Ontology:DOID:2841); severe acute respiratory syndrome (Disease Ontology:DOID:2945); interstitial lung disease (Disease Ontology:DOID:3082); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); tracheal stenosis (Disease Ontology:DOID:3227); atopic dermatitis (Disease Ontology:DOID:3310); carotid artery disease (Disease Ontology:DOID:3407); pancreatic ductal adenocarcinoma (Disease Ontology:DOID:3498); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); pulmonary fibrosis (Disease Ontology:DOID:3770); insulinoma (Disease Ontology:DOID:3892); renal cell carcinoma (Disease Ontology:DOID:4450); rhinitis (Disease Ontology:DOID:4483); cholangiocarcinoma (Disease Ontology:DOID:4947); myelofibrosis (Disease Ontology:DOID:4971); liver cirrhosis (Disease Ontology:DOID:5082); pneumonia (Disease Ontology:DOID:552); oral submucous fibrosis (Disease Ontology:DOID:5773); myocardial infarction (Disease Ontology:DOID:5844); pulmonary hypertension (Disease Ontology:DOID:6432); localized scleroderma (Disease Ontology:DOID:8472); lung disease (Disease Ontology:DOID:850); chronic myeloid leukemia (Disease Ontology:DOID:8552); actinic keratosis (Disease Ontology:DOID:8866); psoriasis (Disease Ontology:DOID:8893); autoimmune thrombocytopenic purpura (Disease Ontology:DOID:8924); colorectal cancer (Disease Ontology:DOID:9256); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); multiple myeloma (Disease Ontology:DOID:9538); aphthous stomatitis (Disease Ontology:DOID:9663); pulmonary emphysema (Disease Ontology:DOID:9675); type 1 diabetes mellitus (Disease Ontology:DOID:9744); obesity (Disease Ontology:DOID:9970)",
        "pathway": " (dre:563884)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_692338.2. COMPLETENESS: full length., [RefSeq]; Required to maintain the Transforming growth factor beta-1 (TGF-beta-1) chain in a latent state during storage in extracellular matrix. Associates non-covalently with TGF-beta-1 and regulates its activation via interaction with 'milieu molecules', such as LTBP1, LRRC32/GARP and LRRC33/NRROS, that control activation of TGF-beta-1. Interaction with integrins (ITGAV:ITGB6 or ITGAV:ITGB8) results in distortion of the Latency-associated peptide chain and subsequent release of the active TGF-beta-1., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 63,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8N7UT62",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005125 cytokine activity;GO:0008083 growth factor activity",
        "go_cellular_component": "GO:0005615 extracellular space",
        "go_biological_process": "GO:0007507 heart development;GO:0030154 cell differentiation;GO:0042127 regulation of cell population proliferation;GO:0007254 JNK cascade;GO:0060218 hematopoietic stem cell differentiation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E9QHW0-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E9QIX9-1",
        "uniprot_id": [
            {
                "id": "E9QIX9_DANRE",
                "url": "https://www.uniprot.org/uniprot/E9QIX9",
                "type": "external"
            }
        ],
        "mass": 69759.0,
        "length": 606,
        "protein_name": "Matrix metalloproteinase-24",
        "gene_name": "mmp24",
        "organism": "Zebrafish",
        "refseq_name": "matrix metalloproteinase-24",
        "refseq_ac": [
            {
                "id": "XP_699803",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_699803",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mmp24",
        "gene_names_refseq": "mmp24",
        "protein_names_uniprotkb": "Matrix metalloproteinase-24",
        "protein_names_refseq": "matrix metalloproteinase-24",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:571143);  (R-DRE-1592389)",
        "pathway_count": 2,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_699803.3. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 1,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8N7UTI0",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding",
        "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0031012 extracellular matrix",
        "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization;GO:0030574 collagen catabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E9QIX9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000001.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E9QJF1-1",
        "uniprot_id": [
            {
                "id": "E9QJF1_DANRE",
                "url": "https://www.uniprot.org/uniprot/E9QJF1",
                "type": "external"
            }
        ],
        "mass": 72027.0,
        "length": 628,
        "protein_name": "alpha-1,2-Mannosidase",
        "gene_name": "edem1",
        "organism": "Zebrafish",
        "refseq_name": "ER degradation-enhancing alpha-mannosidase-like protein 1",
        "refseq_ac": [
            {
                "id": "NP_957483",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957483",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "edem1; zgc:55816",
        "gene_names_refseq": "edem1; zgc:55816",
        "protein_names_uniprotkb": "alpha-1,2-Mannosidase; 3.2.1.-",
        "protein_names_refseq": "ER degradation-enhancing alpha-mannosidase-like protein 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:394164)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "19127516;19240133;21538441;21790674;23798569;35734917;36017776;36843607;37633055;38420496",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC045461.1, GFIL01009154.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On or before May 14, 2015 this sequence version replaced XP_005166083.1, NP_957483.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1PFS6",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005509 calcium ion binding;GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity",
        "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0044322 endoplasmic reticulum quality control compartment",
        "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:1904380 endoplasmic reticulum mannose trimming;GO:1904154 positive regulation of retrograde protein transport, ER to cytosol;GO:0006986 response to unfolded protein",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "E9QJF1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1Q4W9-1",
        "uniprot_id": [
            {
                "id": "F1Q4W9_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1Q4W9",
                "type": "external"
            }
        ],
        "mass": 223733.0,
        "length": 2020,
        "protein_name": "Cell adhesion molecule DSCAM",
        "gene_name": "dscamb",
        "organism": "Zebrafish",
        "refseq_name": "cell adhesion molecule DSCAM isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009289749",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009289749",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "dscamb",
        "gene_names_refseq": "dscamb",
        "protein_names_uniprotkb": "Cell adhesion molecule DSCAM",
        "protein_names_refseq": "cell adhesion molecule DSCAM isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:386937);  (R-DRE-376172)",
        "pathway_count": 2,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 3,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 3,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 3,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M3B0R5",
        "ec_number_list": [],
        "go_molecular_function": "GO:0098632 cell-cell adhesion mediator activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0043025 neuronal cell body;GO:0045202 synapse",
        "go_biological_process": "GO:0048484 enteric nervous system development;GO:0007417 central nervous system development;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007411 axon guidance;GO:0070593 dendrite self-avoidance",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "F1Q4W9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1Q514-1",
        "uniprot_id": [
            {
                "id": "EXO5_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1Q514",
                "type": "external"
            }
        ],
        "mass": 44989.0,
        "length": 394,
        "protein_name": "Exonuclease V",
        "gene_name": "exo5",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "exo5; Exo V; zgc:123272",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Exonuclease V; 3.1.-.-; Exo V",
        "protein_names_refseq": "",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:641427)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "23594743;28440030",
        "class_list": "",
        "function": "Single-stranded DNA (ssDNA) bidirectional exonuclease involved in DNA repair. Probably involved in DNA repair following ultraviolet (UV) irradiation and interstrand cross-links (ICLs) damage. Has both 5'-3' and 3'-5' exonuclease activities with a strong preference for 5'-ends (By similarity)., [UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_s_glycosites": 0,
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        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
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        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
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        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003677 DNA binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0045145 single-stranded DNA 5'-3' DNA exonuclease activity;GO:0004527 exonuclease activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol",
        "go_biological_process": "GO:0036297 interstrand cross-link repair;GO:0006281 DNA repair",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "F1Q514-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1Q575-1",
        "uniprot_id": [
            {
                "id": "NNRD_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1Q575",
                "type": "external"
            }
        ],
        "mass": 35873.0,
        "length": 330,
        "protein_name": "ATP-dependent (S)-NAD(P)H-hydrate dehydratase",
        "gene_name": "naxd",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "naxd; carkd; zgc:171429",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "ATP-dependent (S)-NAD(P)H-hydrate dehydratase; 4.2.1.93; ATP-dependent NAD(P)HX dehydratase; NAD(P)HX dehydratase",
        "protein_names_refseq": "",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:797867);  (R-DRE-196807)",
        "pathway_count": 2,
        "publication_count": 3,
        "publication_id_list": "23594743;26469318;27189481",
        "class_list": "",
        "function": "Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "biomarker_type": "",
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                "id": "4.2.1.93",
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        ],
        "go_molecular_function": "GO:0047453 ATP-dependent NAD(P)H-hydrate dehydratase activity;GO:0005524 ATP binding",
        "go_cellular_component": "",
        "go_biological_process": "GO:0046496 nicotinamide nucleotide metabolic process;GO:0110051 metabolite repair",
        "synthesized_glycan_count": 0,
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        "uniprot_id": [
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        ],
        "mass": 46100.0,
        "length": 409,
        "protein_name": "Alpha-galactosidase",
        "gene_name": "gla",
        "organism": "Zebrafish",
        "refseq_name": "alpha-galactosidase A precursor",
        "refseq_ac": [
            {
                "id": "NP_001006103",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006103",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "gla; zgc:101584",
        "gene_names_refseq": "gla; zgc:101584",
        "protein_names_uniprotkb": "Alpha-galactosidase; 3.2.1.-",
        "protein_names_refseq": "alpha-galactosidase A precursor",
        "tax_id": 7955,
        "disease": "Fabry disease (Disease Ontology:DOID:14499)",
        "pathway": " (dre:450083);  (R-DRE-6798695);  (R-DRE-9840310)",
        "pathway_count": 3,
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        "publication_id_list": "30399334;31048868;34135935;35242583;36161547;36613802;37670295",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC083209.1, GFIL01011505.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Jun 19, 2015 this sequence version replaced NP_001006103.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Catalyzes the hydrolysis of glycosphingolipids and participates in their degradation in the lysosome., [UniProtKB, UniProtKB]; Proteomic analysis unveils Gb3-independent alterations and mitochondrial dysfunction in a gla[-/-] zebrafish model of Fabry disease. Publication Status: Online-Only, [RefSeq, PubMed]",
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        "secondary_ac_list": "A0A8M1N2Y5",
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                "id": "3.4.21.4",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.4",
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                "id": "2.4.1.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.1",
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                "id": "3.1.27.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.27.-",
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            {
                "id": "4.6.1.19",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.19",
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                "id": "3.5.3.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.1",
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            },
            {
                "id": "3.2.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.-",
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                "id": "3.2.1.31",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.31",
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                "id": "5.3.4.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.4.1",
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                "id": "3.1.6.4",
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            {
                "id": "3.5.4.4",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.4",
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                "id": "3.1.3.16",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16",
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                "id": "1.1.1.205",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.205",
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            {
                "id": "6.3.4.21",
                "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.21",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6",
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            {
                "id": "5.3.99.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.99.3",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.5.5",
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        ],
        "go_molecular_function": "GO:0004557 alpha-galactosidase activity",
        "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0016020 membrane;GO:0005764 lysosome",
        "go_biological_process": "GO:0009311 oligosaccharide metabolic process;GO:0016139 glycoside catabolic process;GO:0046479 glycosphingolipid catabolic process;GO:0072015 podocyte development;GO:0061333 renal tubule morphogenesis",
        "synthesized_glycan_count": 0,
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                "id": "F1Q5H3_DANRE",
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        ],
        "mass": 142000.0,
        "length": 1232,
        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "slka",
        "organism": "Zebrafish",
        "refseq_name": "STE20-like serine/threonine-protein kinase isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005156928",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005156928",
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        ],
        "gene_names_uniprotkb": "slka; fk52g01; im:7150762; si:ch211-223p8.7; slkn; wu:fk52g01",
        "gene_names_refseq": "fk52g01; im:7150762; si:ch211-223p8.7; slka; slkn; wu:fk52g01",
        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
        "protein_names_refseq": "STE20-like serine/threonine-protein kinase isoform X1",
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        "disease": "",
        "pathway": " (dre:568838);  (R-DRE-8980692);  (R-DRE-9013026);  (R-DRE-9013106)",
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        "publication_id_list": "26469318;27189481;28252024",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0030334 regulation of cell migration;GO:0042981 regulation of apoptotic process",
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        "mass": 38864.0,
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        "protein_name": "UDP-glucose 4-epimerase",
        "gene_name": "gale",
        "organism": "Zebrafish",
        "refseq_name": "UDP-glucose 4-epimerase isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005158580",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005158580",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "gale; fb05f01; im:7147391; wu:fb05f01; zgc:136578",
        "gene_names_refseq": "fb05f01; gale; im:7147391; wu:fb05f01; zgc:136578",
        "protein_names_uniprotkb": "UDP-glucose 4-epimerase; 5.1.3.2",
        "protein_names_refseq": "UDP-glucose 4-epimerase isoform X1",
        "tax_id": 7955,
        "disease": "galactose epimerase deficiency (Disease Ontology:DOID:0111458); thrombocytopenia (Disease Ontology:DOID:1588); galactosemia (Disease Ontology:DOID:9870)",
        "pathway": " (R-DRE-70370)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
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        "total_n_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 3,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M2B5E6",
        "ec_number_list": [
            {
                "id": "5.1.3.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.3.2",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0003978 UDP-glucose 4-epimerase activity;GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity",
        "go_cellular_component": "GO:0005829 cytosol",
        "go_biological_process": "GO:0033499 galactose catabolic process via UDP-galactose, Leloir pathway",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "F1Q5H4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1Q5J2-1",
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            {
                "id": "F1Q5J2_DANRE",
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                "type": "external"
            }
        ],
        "mass": 116268.0,
        "length": 1062,
        "protein_name": "Mitogen-activated protein kinase kinase kinase",
        "gene_name": "map3k10",
        "organism": "Zebrafish",
        "refseq_name": "mitogen-activated protein kinase kinase kinase 10",
        "refseq_ac": [
            {
                "id": "XP_689424",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689424",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "map3k10",
        "gene_names_refseq": "map3k10",
        "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase; 2.7.11.25",
        "protein_names_refseq": "mitogen-activated protein kinase kinase kinase 10",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:560932)",
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        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_689424.3. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 3,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 3,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
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        "mined_s_glycosites": 0,
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        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 3,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8N7TB13",
        "ec_number_list": [
            {
                "id": "2.7.11.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
                "type": "external"
            },
            {
                "id": "2.7.11.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13",
                "type": "external"
            },
            {
                "id": "2.7.11.25",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25",
                "type": "external"
            },
            {
                "id": "2.7.10.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1",
                "type": "external"
            },
            {
                "id": "2.7.11.22",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22",
                "type": "external"
            },
            {
                "id": "2.7.11.21",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21",
                "type": "external"
            },
            {
                "id": "2.7.11.17",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17",
                "type": "external"
            },
            {
                "id": "2.7.12.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1",
                "type": "external"
            },
            {
                "id": "2.7.12.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2",
                "type": "external"
            },
            {
                "id": "2.7.11.24",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24",
                "type": "external"
            },
            {
                "id": "2.7.10.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2",
                "type": "external"
            },
            {
                "id": "2.7.11.23",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23",
                "type": "external"
            },
            {
                "id": "2.7.1.150",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150",
                "type": "external"
            },
            {
                "id": "2.7.11.12",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12",
                "type": "external"
            },
            {
                "id": "2.7.11.39",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39",
                "type": "external"
            },
            {
                "id": "2.7.11.11",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11",
                "type": "external"
            },
            {
                "id": "2.7.1.153",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153",
                "type": "external"
            },
            {
                "id": "2.7.1.137",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137",
                "type": "external"
            },
            {
                "id": "2.7.1.154",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154",
                "type": "external"
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            {
                "id": "2.7.11.26",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26",
                "type": "external"
            },
            {
                "id": "2.7.11.31",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0004706 JUN kinase kinase kinase activity",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0007165 signal transduction;GO:0043065 positive regulation of apoptotic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "F1Q5J2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1Q5J6-1",
        "uniprot_id": [
            {
                "id": "F1Q5J6_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1Q5J6",
                "type": "external"
            }
        ],
        "mass": 129349.0,
        "length": 1142,
        "protein_name": "Adenylate cyclase type 2",
        "gene_name": "adcy2b",
        "organism": "Zebrafish",
        "refseq_name": "adenylate cyclase type 2b isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005170095",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170095",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "adcy2b; si:dkey-266i6.1",
        "gene_names_refseq": "adcy2b; si:dkey-266i6.1",
        "protein_names_uniprotkb": "Adenylate cyclase type 2; 4.6.1.1",
        "protein_names_refseq": "adenylate cyclase type 2b isoform X1",
        "tax_id": 7955,
        "disease": "chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); bipolar disorder (Disease Ontology:DOID:3312)",
        "pathway": " (dre:557902);  (R-DRE-163615);  (R-DRE-170660);  (R-DRE-170670);  (R-DRE-418597);  (R-DRE-5610787)",
        "pathway_count": 6,
        "publication_count": 7,
        "publication_id_list": "15133664;22485131;22584411;24926785;26469318;27189481;30465971",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in signaling cascades downstream of the muscarinic acetylcholine receptors., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "secondary_ac_list": "A0A8M2BHB8",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.1",
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            {
                "id": "2.7.7.85",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.85",
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            }
        ],
        "go_molecular_function": "GO:0004016 adenylate cyclase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0006171 cAMP biosynthetic process;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0035556 intracellular signal transduction",
        "synthesized_glycan_count": 0,
        "hit_score": 0.8,
        "record_id": "F1Q5J6-1",
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        "filter_code": "0000000.0000111.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "F1Q5L6_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1Q5L6",
                "type": "external"
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        ],
        "mass": 69418.0,
        "length": 617,
        "protein_name": "RNA helicase",
        "gene_name": "ddx5",
        "organism": "Zebrafish",
        "refseq_name": "probable ATP-dependent RNA helicase DDX5 isoform 1",
        "refseq_ac": [
            {
                "id": "NP_997777",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997777",
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        ],
        "gene_names_uniprotkb": "ddx5; wu:fa56a07; wu:fb11e01; wu:fb16c10; wu:fb53b05",
        "gene_names_refseq": "ddx5; wu:fa56a07; wu:fb11e01; wu:fb16c10; wu:fb53b05",
        "protein_names_uniprotkb": "RNA helicase; 3.6.4.13",
        "protein_names_refseq": "DEAD (Asp-Glu-Ala-Asp) box polypeptide 5; DEAD box RNA helicase; probable ATP-dependent RNA helicase DDX5 isoform 1",
        "tax_id": 7955,
        "disease": "skin squamous cell carcinoma (Disease Ontology:DOID:3151)",
        "pathway": " (R-DRE-3899300);  (R-DRE-72163);  (R-DRE-9018519);  (R-DRE-9770562)",
        "pathway_count": 4,
        "publication_count": 10,
        "publication_id_list": "15520368;16109975;21383318;22567096;24714733;28252024;28550373;31227602;32094353;32873816",
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        "function": "##Evidence-Data-START## Transcript exon combination :: AY391418.1, GFIL01008484.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On or before Jun 10, 2015 this sequence version replaced XP_005171624.1, NP_997777.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
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                "id": "2.3.2.-",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27",
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            },
            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18",
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                "type": "external"
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                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3",
                "type": "external"
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12",
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                "id": "3.6.4.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13",
                "type": "external"
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6",
                "type": "external"
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16",
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                "type": "external"
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                "id": "7.6.2.2",
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            },
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                "id": "5.6.1.6",
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                "type": "external"
            },
            {
                "id": "7.6.2.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3",
                "type": "external"
            },
            {
                "id": "3.6.1.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5",
                "type": "external"
            },
            {
                "id": "3.6.4.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6",
                "type": "external"
            },
            {
                "id": "3.6.1.15",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15",
                "type": "external"
            },
            {
                "id": "3.6.4.10",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10",
                "type": "external"
            },
            {
                "id": "2.7.7.19",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19",
                "type": "external"
            },
            {
                "id": "5.2.1.8",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8",
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            },
            {
                "id": "5.6.2.-",
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            },
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                "id": "2.7.1.78",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.78",
                "type": "external"
            },
            {
                "id": "2.7.7.7",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7",
                "type": "external"
            },
            {
                "id": "2.7.7.49",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49",
                "type": "external"
            },
            {
                "id": "2.1.1.319",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.319",
                "type": "external"
            },
            {
                "id": "5.6.2.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5",
                "type": "external"
            },
            {
                "id": "2.3.1.48",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48",
                "type": "external"
            },
            {
                "id": "2.3.1.57",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.57",
                "type": "external"
            },
            {
                "id": "3.6.5.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-",
                "type": "external"
            },
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                "id": "2.7.7.52",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.52",
                "type": "external"
            },
            {
                "id": "3.6.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003730 mRNA 3'-UTR binding;GO:0003724 RNA helicase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:1990904 ribonucleoprotein complex",
        "go_biological_process": "GO:0001556 oocyte maturation;GO:0000380 alternative mRNA splicing, via spliceosome",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "F1Q5L6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1Q5N1-1",
        "uniprot_id": [
            {
                "id": "F1Q5N1_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1Q5N1",
                "type": "external"
            }
        ],
        "mass": 74662.0,
        "length": 664,
        "protein_name": "Leishmanolysin-like peptidase",
        "gene_name": "lmln",
        "organism": "Zebrafish",
        "refseq_name": "leishmanolysin-like peptidase",
        "refseq_ac": [
            {
                "id": "XP_689096",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689096",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "lmln",
        "gene_names_refseq": "lmln",
        "protein_names_uniprotkb": "Leishmanolysin-like peptidase; 3.4.24.-",
        "protein_names_refseq": "leishmanolysin-like peptidase",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:560606)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_689096.4. COMPLETENESS: full length., [RefSeq]; Metalloprotease., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "mined_s_glycosites": 0,
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        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8N7TEQ0",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding;GO:0008233 peptidase activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005811 lipid droplet;GO:0016020 membrane",
        "go_biological_process": "GO:0006508 proteolysis;GO:0007155 cell adhesion;GO:0051301 cell division;GO:0002040 sprouting angiogenesis;GO:0097324 melanocyte migration",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "F1Q5N1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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            {
                "id": "F1Q5Q7_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1Q5Q7",
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        ],
        "mass": 102372.0,
        "length": 899,
        "protein_name": "Exosome complex component 10",
        "gene_name": "exosc10",
        "organism": "Zebrafish",
        "refseq_name": "exosome complex component 10",
        "refseq_ac": [
            {
                "id": "NP_957383",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957383",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "exosc10; Pmscl2; zgc:55695",
        "gene_names_refseq": "Pmscl2; exosc10; zgc:55695",
        "protein_names_uniprotkb": "Exosome complex component 10",
        "protein_names_refseq": "exosome complex component 10",
        "tax_id": 7955,
        "disease": "primary ovarian insufficiency (Disease Ontology:DOID:5426)",
        "pathway": " (dre:394064);  (R-DRE-6791226);  (R-DRE-9930044)",
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        "publication_id_list": "12477932;21873635",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC045429.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CR318666.9. On Oct 31, 2008 this sequence version replaced NP_957383.1., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1PFK9",
        "ec_number_list": [],
        "go_molecular_function": "GO:0046872 metal ion binding;GO:0000166 nucleotide binding;GO:0003727 single-stranded RNA binding;GO:0000175 3'-5'-RNA exonuclease activity",
        "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0000176 nuclear exosome (RNase complex)",
        "go_biological_process": "GO:0006281 DNA repair;GO:0071044 histone mRNA catabolic process;GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0071035 nuclear polyadenylation-dependent rRNA catabolic process;GO:0071038 TRAMP-dependent tRNA surveillance pathway",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "F1Q5Q7-1",
        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
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                "url": "https://www.uniprot.org/uniprot/F1Q6R0",
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        ],
        "mass": 41666.0,
        "length": 367,
        "protein_name": "C-X-C chemokine receptor type 3",
        "gene_name": "cxcr3.1",
        "organism": "Zebrafish",
        "refseq_name": "C-X-C chemokine receptor type 3.1",
        "refseq_ac": [
            {
                "id": "NP_001082899",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082899",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cxcr3.1; sb:eu378",
        "gene_names_refseq": "cxcr3.1; sb:eu378",
        "protein_names_uniprotkb": "C-X-C chemokine receptor type 3; Interferon-inducible protein 10 receptor",
        "protein_names_refseq": "C-X-C chemokine receptor type 3.1; CXCR3ab; chemokine (C-X-C motif) receptor 3.1; dr-chr16-CXCR3-41.8-EK27498",
        "tax_id": 7955,
        "disease": "invasive aspergillosis (Disease Ontology:DOID:0050073); dilated cardiomyopathy (Disease Ontology:DOID:12930); pulmonary sarcoidosis (Disease Ontology:DOID:13406); thoracic aortic aneurysm (Disease Ontology:DOID:14004); cystic fibrosis (Disease Ontology:DOID:1485); renovascular hypertension (Disease Ontology:DOID:1591); asthma (Disease Ontology:DOID:2841); high grade glioma (Disease Ontology:DOID:3070); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); middle cerebral artery infarction (Disease Ontology:DOID:3525); systemic scleroderma (Disease Ontology:DOID:418); coronary restenosis (Disease Ontology:DOID:4247); myasthenia gravis (Disease Ontology:DOID:437); rheumatoid arthritis (Disease Ontology:DOID:7148); myocarditis (Disease Ontology:DOID:820); extrinsic allergic alveolitis (Disease Ontology:DOID:841); ulcerative colitis (Disease Ontology:DOID:8577); pulmonary emphysema (Disease Ontology:DOID:9675)",
        "pathway": " (dre:654692);  (R-DRE-380108);  (R-DRE-418594)",
        "pathway_count": 3,
        "publication_count": 10,
        "publication_id_list": "16365434;23145839;24349563;25573892;26083432;28234357;28351983;31529512;32709934;33234717",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01019848.1, CK017467.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476799, SAMEA708836 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Jul 21, 2025 this sequence version replaced NP_001082899.2. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; The demonstration of a conserved CXCR3-CXCL11 signaling axis in zebrafish extends the translational applicability of this model for studying diseases involving the innate immune system., [RefSeq, PubMed]",
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1NCV2",
        "ec_number_list": [],
        "go_molecular_function": "GO:0016493 C-C chemokine receptor activity;GO:0016494 C-X-C chemokine receptor activity;GO:0019957 C-C chemokine binding",
        "go_cellular_component": "GO:0009897 external side of plasma membrane",
        "go_biological_process": "GO:0001525 angiogenesis;GO:0006954 inflammatory response;GO:0006955 immune response;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0019722 calcium-mediated signaling",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "F1Q6R0-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "F1Q740_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1Q740",
                "type": "external"
            }
        ],
        "mass": 143438.0,
        "length": 1271,
        "protein_name": "Valine--tRNA ligase",
        "gene_name": "vars1",
        "organism": "Zebrafish",
        "refseq_name": "valine--tRNA ligase",
        "refseq_ac": [
            {
                "id": "NP_001298275",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001298275",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "vars1; CHUNP6879; im:7137378; vars2; vars; wu:fb07a11; wu:fb07d10",
        "gene_names_refseq": "CHUNP6879; im:7137378; vars1; vars2; vars; wu:fb07a11; wu:fb07d10",
        "protein_names_uniprotkb": "Valine--tRNA ligase; 6.1.1.9; Valyl-tRNA synthetase",
        "protein_names_refseq": "valine--tRNA ligase; valyl-tRNA synthetase 2",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:114427)",
        "pathway_count": 1,
        "publication_count": 8,
        "publication_id_list": "16109975;16448862;25267534;26469318;27402763;28252024;28934368;30755616",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395064.1942886.1, GDQH01010348.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505381 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Dec 3, 2025 this sequence version replaced NP_001298275.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Authors report an allelic series consisting of seven novel and two previously reported biallelic variants in valyl-tRNA synthetase (VARS) in ten patients with a developmental encephalopathy with microcephaly, often associated with early-onset epilepsy. Publication Status: Online-Only, [RefSeq, PubMed]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M1P7Y5",
        "ec_number_list": [
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                "id": "6.1.1.9",
                "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.9",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0002161 aminoacyl-tRNA deacylase activity;GO:0004832 valine-tRNA ligase activity;GO:0005524 ATP binding;GO:0016874 ligase activity",
        "go_cellular_component": "GO:0005829 cytosol",
        "go_biological_process": "GO:0006438 valyl-tRNA aminoacylation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.9,
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        "record_type": "protein",
        "filter_code": "0000000.0000101.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
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    {
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        "protein_name": "Calcium-transporting ATPase",
        "gene_name": "si:dkey-28b4.8",
        "organism": "Zebrafish",
        "refseq_name": "sarcoplasmic/endoplasmic reticulum calcium ATPase 2",
        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_684227",
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        ],
        "gene_names_uniprotkb": "si:dkey-28b4.8",
        "gene_names_refseq": "si:dkey-28b4.8",
        "protein_names_uniprotkb": "Calcium-transporting ATPase; 7.2.2.10",
        "protein_names_refseq": "sarcoplasmic/endoplasmic reticulum calcium ATPase 2",
        "tax_id": 7955,
        "disease": "Brody myopathy (Disease Ontology:DOID:0050692); heart disease (Disease Ontology:DOID:114)",
        "pathway": " (dre:562640)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the hydrolysis of ATP coupled with the transport of calcium., [UniProtKB, UniProtKB]",
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            {
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            }
        ],
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        "go_cellular_component": "GO:0016020 membrane;GO:0033017 sarcoplasmic reticulum membrane",
        "go_biological_process": "GO:0000045 autophagosome assembly;GO:0006874 intracellular calcium ion homeostasis;GO:0070588 calcium ion transmembrane transport;GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling",
        "synthesized_glycan_count": 0,
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    },
    {
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            {
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                "url": "https://www.uniprot.org/uniprot/F1Q7Z7",
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        ],
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        "length": 469,
        "protein_name": "Dynein axonemal assembly factor 3",
        "gene_name": "dnaaf3",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "dnaaf3; si:dkey-224b4.3",
        "gene_names_refseq": "",
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        "protein_names_refseq": "",
        "tax_id": 7955,
        "disease": "Kartagener syndrome (Disease Ontology:DOID:0050144); visceral heterotaxy (Disease Ontology:DOID:0050545); primary ciliary dyskinesia 2 (Disease Ontology:DOID:0110626)",
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        "publication_id_list": "22387996;23594743",
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        "function": "Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia., [UniProtKB, PubMed]",
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        "protein_names_uniprotkb": "DNA polymerase eta; 2.7.7.7; RAD30 homolog A",
        "protein_names_refseq": "DNA polymerase eta",
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        "disease": "xeroderma pigmentosum (Disease Ontology:DOID:0050427); female breast cancer (Disease Ontology:DOID:0050671); xeroderma pigmentosum variant type (Disease Ontology:DOID:0110847)",
        "pathway": " (dre:678520);  (R-DRE-110320);  (R-DRE-5656169);  (R-DRE-5685942);  (R-DRE-5693537)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC115307.1, GDQH01018363.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA4476732, SAMEA4476733 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On Aug 22, 2015 this sequence version replaced NP_001035337.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
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            {
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            {
                "id": "2.7.7.-",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.23",
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            {
                "id": "2.7.7.49",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12",
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
                "type": "external"
            },
            {
                "id": "3.1.-.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-",
                "type": "external"
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            {
                "id": "2.7.7.102",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.102",
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            {
                "id": "4.2.99.18",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18",
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            },
            {
                "id": "4.2.99.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.-",
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            },
            {
                "id": "3.6.4.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6",
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.1",
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            }
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        "go_cellular_component": "GO:0005634 nucleus;GO:0035861 site of double-strand break;GO:0005657 replication fork",
        "go_biological_process": "GO:0006281 DNA repair;GO:0009314 response to radiation;GO:0042276 error-prone translesion synthesis;GO:0010225 response to UV-C",
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                "id": "F1Q883_DANRE",
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        ],
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        "length": 511,
        "protein_name": "6-phosphogluconate dehydrogenase, decarboxylating",
        "gene_name": "pgd",
        "organism": "Zebrafish",
        "refseq_name": "6-phosphogluconate dehydrogenase, decarboxylating",
        "refseq_ac": [
            {
                "id": "NP_998618",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998618",
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            }
        ],
        "gene_names_uniprotkb": "pgd; fi03d03; wu:fi03d03; zgc:111848; zgc:55585",
        "gene_names_refseq": "fi03d03; pgd; wu:fi03d03; zgc:111848; zgc:55585",
        "protein_names_uniprotkb": "6-phosphogluconate dehydrogenase, decarboxylating; 1.1.1.44",
        "protein_names_refseq": "6-phosphogluconate dehydrogenase, decarboxylating; phosphogluconate hydrogenase",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:406762);  (R-DRE-71336)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC044196.1, AY391449.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On or before Feb 5, 2016 this sequence version replaced NP_998717.1, NP_998618.1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference genome strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005829 cytosol",
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        "protein_name": "Solute carrier family 26 member 3 isoform X1",
        "gene_name": "slc26a3.1",
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        "refseq_name": "solute carrier family 26 member 3 isoform X1",
        "refseq_ac": [
            {
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        "gene_names_refseq": "si:dkey-31f5.2; slc26a3.1; slc26a3",
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        "protein_names_refseq": "solute carrier family 26 member 3 isoform X1",
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        "disease": "congenital secretory chloride diarrhea 1 (Disease Ontology:DOID:0060296); diarrhea (Disease Ontology:DOID:13250)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0008510 sodium:bicarbonate symporter activity;GO:0008271 secondary active sulfate transmembrane transporter activity",
        "go_cellular_component": "GO:0016020 membrane",
        "go_biological_process": "GO:0055081 monoatomic anion homeostasis;GO:0006821 chloride transport;GO:0009651 response to salt stress",
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        "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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            {
                "id": "E9QDQ9_DANRE",
                "url": "https://www.uniprot.org/uniprot/E9QDQ9",
                "type": "external"
            }
        ],
        "mass": 102511.0,
        "length": 911,
        "protein_name": "E3 ubiquitin-protein ligase MARCHF6",
        "gene_name": "marchf6",
        "organism": "Zebrafish",
        "refseq_name": "E3 ubiquitin-protein ligase MARCHF6",
        "refseq_ac": [
            {
                "id": "NP_001278636",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001278636",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "marchf6; fa98a02; im:7161807; march6; si:dkey-40c17.2; wu:fa98a02",
        "gene_names_refseq": "fa98a02; im:7161807; march6; marchf6; si:dkey-40c17.2; wu:fa98a02",
        "protein_names_uniprotkb": "E3 ubiquitin-protein ligase MARCHF6; 2.3.2.27; Membrane-associated RING finger protein 6; Membrane-associated RING-CH protein VI",
        "protein_names_refseq": "E3 ubiquitin-protein ligase MARCHF6",
        "tax_id": 7955,
        "disease": "familial adult myoclonic epilepsy 3 (Disease Ontology:DOID:0111695)",
        "pathway": " (dre:100002072)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "26469318;37054851",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395013.589308.1, SRR32588728.31128267.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EB935699.1, CK024583.1, EB949406.1, EB899125.1, CT661348.1, JBMGRA010000002.1 and EH451889.1. On Apr 25, 2014 this sequence version replaced XP_002660875.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "reported_o_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "total_n_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M1P6Q7",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity",
        "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0036503 ERAD pathway",
        "synthesized_glycan_count": 0,
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        "record_id": "E9QDQ9-1",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "E9QB24-1",
        "uniprot_id": [
            {
                "id": "E9QB24_DANRE",
                "url": "https://www.uniprot.org/uniprot/E9QB24",
                "type": "external"
            }
        ],
        "mass": 109525.0,
        "length": 982,
        "protein_name": "Meckelin isoform X1",
        "gene_name": "tmem67",
        "organism": "Zebrafish",
        "refseq_name": "meckelin isoform X1",
        "refseq_ac": [
            {
                "id": "XP_700974",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_700974",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tmem67",
        "gene_names_refseq": "tmem67",
        "protein_names_uniprotkb": "Meckelin isoform X1",
        "protein_names_refseq": "meckelin isoform X1",
        "tax_id": 7955,
        "disease": "visceral heterotaxy (Disease Ontology:DOID:0050545); Meckel syndrome (Disease Ontology:DOID:0050778); ciliopathy (Disease Ontology:DOID:0060340); Meckel syndrome 3 (Disease Ontology:DOID:0070117); Bardet-Biedl syndrome 14 (Disease Ontology:DOID:0110136); autosomal recessive polycystic kidney disease (Disease Ontology:DOID:0110861); Joubert syndrome 6 (Disease Ontology:DOID:0111001); nephronophthisis 11 (Disease Ontology:DOID:0111118); COACH syndrome (Disease Ontology:DOID:0111589); portal hypertension (Disease Ontology:DOID:10762); meningocele (Disease Ontology:DOID:1088); hydrocephalus (Disease Ontology:DOID:10908); coloboma (Disease Ontology:DOID:12270); nephronophthisis (Disease Ontology:DOID:12712); communicating hydrocephalus (Disease Ontology:DOID:1573); Bardet-Biedl syndrome (Disease Ontology:DOID:1935); cystic kidney disease (Disease Ontology:DOID:2975); proteinuria (Disease Ontology:DOID:576)",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_700974.3. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "total_o_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "A0A8N7T8D1",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0036038 MKS complex",
        "go_biological_process": "GO:0060271 cilium assembly;GO:0007369 gastrulation;GO:0003341 cilium movement;GO:0060028 convergent extension involved in axis elongation;GO:0060027 convergent extension involved in gastrulation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "E9QB24-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1Q555-1",
        "uniprot_id": [
            {
                "id": "F1Q555_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1Q555",
                "type": "external"
            }
        ],
        "mass": 80595.0,
        "length": 726,
        "protein_name": "Glycerol-3-phosphate dehydrogenase, mitochondrial",
        "gene_name": "gpd2",
        "organism": "Zebrafish",
        "refseq_name": "glycerol-3-phosphate dehydrogenase, mitochondrial",
        "refseq_ac": [
            {
                "id": "NP_001428970",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428970",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "gpd2; cb853; im:7147983; wu:fe02f02; zgc:153729",
        "gene_names_refseq": "cb853; gpd2; im:7147983; wu:fe02f02; zgc:153729",
        "protein_names_uniprotkb": "Glycerol-3-phosphate dehydrogenase, mitochondrial; 1.1.5.3",
        "protein_names_refseq": "glycerol-3-phosphate dehydrogenase, mitochondrial; mGPDH",
        "tax_id": 7955,
        "disease": "type 2 diabetes mellitus (Disease Ontology:DOID:9352)",
        "pathway": "",
        "pathway_count": 0,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588727.119062.1, SRR32588731.1569313.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On Jul 21, 2025 this sequence version replaced XP_005165900.1., [RefSeq]; Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M2BD42",
        "ec_number_list": [
            {
                "id": "1.1.5.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.5.3",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004368 glycerol-3-phosphate dehydrogenase (quinone) activity;GO:0005509 calcium ion binding",
        "go_cellular_component": "GO:0005739 mitochondrion",
        "go_biological_process": "GO:0006072 glycerol-3-phosphate metabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "F1Q555-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1REQ6-1",
        "uniprot_id": [
            {
                "id": "F1REQ6_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1REQ6",
                "type": "external"
            }
        ],
        "mass": 94816.0,
        "length": 840,
        "protein_name": "Prickle-like protein 2b isoform X2",
        "gene_name": "prickle2b",
        "organism": "Zebrafish",
        "refseq_name": "prickle-like protein 2b isoform X2",
        "refseq_ac": [
            {
                "id": "XP_005155884",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155884",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "prickle2b; cb886; im:7138215; pk2; prickle2",
        "gene_names_refseq": "cb886; im:7138215; pk2; prickle2b; prickle2",
        "protein_names_uniprotkb": "Prickle-like protein 2b isoform X2",
        "protein_names_refseq": "prickle-like protein 2b isoform X2",
        "tax_id": 7955,
        "disease": "epilepsy (Disease Ontology:DOID:1826)",
        "pathway": " (dre:368250)",
        "pathway_count": 1,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M2B1U8;A0AC58GPI8;A0AC58GPK5;A0AC58GPM5",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008270 zinc ion binding",
        "go_cellular_component": "",
        "go_biological_process": "GO:0003407 neural retina development;GO:0060271 cilium assembly;GO:0070121 Kupffer's vesicle development;GO:0032402 melanosome transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "F1REQ6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "F1R7X5_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1R7X5",
                "type": "external"
            }
        ],
        "mass": 46439.0,
        "length": 432,
        "protein_name": "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial",
        "gene_name": "suclg2",
        "organism": "Zebrafish",
        "refseq_name": "succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial",
        "refseq_ac": [
            {
                "id": "NP_001373238",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373238",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "suclg2; SUCLG2; cb625; fd44e06; wu:fd44e06",
        "gene_names_refseq": "cb625; fd44e06; suclg2; wu:fd44e06",
        "protein_names_uniprotkb": "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; 6.2.1.4; G-SCS; GTP-specific succinyl-CoA synthetase subunit beta; GTPSCS; SCS-betaG; Succinyl-CoA synthetase beta-G chain",
        "protein_names_refseq": "SUCLGb; succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; succinate-CoA ligase, GDP-forming, beta subunit; succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:317746)",
        "pathway_count": 1,
        "publication_count": 9,
        "publication_id_list": "16109975;19500364;26469318;28252024;29227944;30317609;32036144;32806454;37746814",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC056551.1, GDQQ01003492.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On or before Aug 19, 2020 this sequence version replaced XP_021335446.1, XP_001923821.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit., [UniProtKB, HAMAP, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
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        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0A8M9QHZ9",
        "ec_number_list": [
            {
                "id": "6.2.1.4",
                "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.4",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0004775 succinate-CoA ligase (ADP-forming) activity;GO:0004776 succinate-CoA ligase (GDP-forming) activity",
        "go_cellular_component": "GO:0005739 mitochondrion",
        "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006104 succinyl-CoA metabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 1.0,
        "record_id": "F1R7X5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "F1R1N9_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1R1N9",
                "type": "external"
            }
        ],
        "mass": 72807.0,
        "length": 657,
        "protein_name": "CD2-associated protein",
        "gene_name": "cd2ap",
        "organism": "Zebrafish",
        "refseq_name": "CD2-associated protein",
        "refseq_ac": [
            {
                "id": "NP_001008583",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008583",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cd2ap; cd2apl; fj51c01; im:7153970; si:ch211-207n9.1; wu:fj51c01; zgc:103705",
        "gene_names_refseq": "cd2apl; cd2ap; fj51c01; im:7153970; si:ch211-207n9.1; wu:fj51c01; zgc:103705",
        "protein_names_uniprotkb": "CD2-associated protein; Osteoclast-stimulating factor 1",
        "protein_names_refseq": "CD2-associated protein",
        "tax_id": 7955,
        "disease": "focal segmental glomerulosclerosis 3 (Disease Ontology:DOID:0112245); focal segmental glomerulosclerosis (Disease Ontology:DOID:1312); end stage renal disease (Disease Ontology:DOID:783)",
        "pathway": " (dre:494040)",
        "pathway_count": 1,
        "publication_count": 6,
        "publication_id_list": "25962121;26469318;27189481;27441654;28228401;40044042",
        "class_list": "",
        "function": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EB864755.1, BC086846.1, DT081164.1, DT075242.1 and BX511269.12. On May 1, 2007 this sequence version replaced NP_001008583.1., [RefSeq]; Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis. Plays a role in epithelial cell junctions formation., [UniProtKB, UniProtKB, UniProtKB]; Tank1/Tank2 inhibition aggravates kidney injury in the absence of CD2AP. Publication Status: Online-Only, [RefSeq, PubMed]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_o_glycosites": 0,
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        "mined_s_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 1,
        "reported_c_glycosites_with_glycan": 0,
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        "missing_score": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1N3I0",
        "ec_number_list": [],
        "go_molecular_function": "GO:0017124 SH3 domain binding;GO:0030674 protein-macromolecule adaptor activity",
        "go_cellular_component": "GO:0005856 cytoskeleton;GO:0001726 ruffle;GO:0032991 protein-containing complex;GO:0070161 anchoring junction;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0051301 cell division;GO:0032835 glomerulus development;GO:0003094 glomerular filtration;GO:0039021 pronephric glomerulus development;GO:0007015 actin filament organization",
        "synthesized_glycan_count": 0,
        "hit_score": 0.9,
        "record_id": "F1R1N9-1",
        "record_type": "protein",
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    },
    {
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            {
                "id": "F1QUT2_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1QUT2",
                "type": "external"
            }
        ],
        "mass": 71243.0,
        "length": 633,
        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "mak",
        "organism": "Zebrafish",
        "refseq_name": "serine/threonine-protein kinase MAK isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009295564",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009295564",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mak; Ick; fj04c02; payday; pday; wu:fj04c02; zgc:56603",
        "gene_names_refseq": "Ick; fj04c02; mak; payday; pday; wu:fj04c02; zgc:56603",
        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
        "protein_names_refseq": "serine/threonine-protein kinase MAK isoform X1",
        "tax_id": 7955,
        "disease": "retinitis pigmentosa 62 (Disease Ontology:DOID:0110380)",
        "pathway": " (dre:335339)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "secondary_ac_list": "A0A8M3AVX2;A0AC58IPI2",
        "ec_number_list": [
            {
                "id": "2.7.11.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
                "type": "external"
            },
            {
                "id": "2.7.11.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13",
                "type": "external"
            },
            {
                "id": "2.7.11.25",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25",
                "type": "external"
            },
            {
                "id": "2.7.10.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1",
                "type": "external"
            },
            {
                "id": "2.7.11.22",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22",
                "type": "external"
            },
            {
                "id": "2.7.11.21",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21",
                "type": "external"
            },
            {
                "id": "2.7.11.17",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17",
                "type": "external"
            },
            {
                "id": "2.7.12.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1",
                "type": "external"
            },
            {
                "id": "2.7.12.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2",
                "type": "external"
            },
            {
                "id": "2.7.11.24",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24",
                "type": "external"
            },
            {
                "id": "2.7.10.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2",
                "type": "external"
            },
            {
                "id": "2.7.11.23",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23",
                "type": "external"
            },
            {
                "id": "2.7.1.150",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150",
                "type": "external"
            },
            {
                "id": "2.7.11.12",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12",
                "type": "external"
            },
            {
                "id": "2.7.11.39",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39",
                "type": "external"
            },
            {
                "id": "2.7.11.11",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11",
                "type": "external"
            },
            {
                "id": "2.7.1.153",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153",
                "type": "external"
            },
            {
                "id": "2.7.1.137",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137",
                "type": "external"
            },
            {
                "id": "2.7.1.154",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154",
                "type": "external"
            },
            {
                "id": "2.7.11.26",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26",
                "type": "external"
            },
            {
                "id": "2.7.11.31",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016301 kinase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005856 cytoskeleton;GO:0005929 cilium;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0060271 cilium assembly;GO:0035845 photoreceptor cell outer segment organization;GO:0044458 motile cilium assembly;GO:0035556 intracellular signal transduction;GO:0042073 intraciliary transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "F1QUT2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1R6L2-1",
        "uniprot_id": [
            {
                "id": "F1R6L2_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1R6L2",
                "type": "external"
            }
        ],
        "mass": 116293.0,
        "length": 1048,
        "protein_name": "Huntingtin-interacting protein 1",
        "gene_name": "hip1",
        "organism": "Zebrafish",
        "refseq_name": "huntingtin-interacting protein 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005157489",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157489",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "hip1; fb98d04; wu:fb98d04",
        "gene_names_refseq": "fb98d04; hip1; wu:fb98d04",
        "protein_names_uniprotkb": "Huntingtin-interacting protein 1; Huntingtin-interacting protein I",
        "protein_names_refseq": "huntingtin-interacting protein 1 isoform X1",
        "tax_id": 7955,
        "disease": "",
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        "pathway_count": 0,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis., [UniProtKB, UniProtKB, UniProtKB]; Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Regulates presynaptic nerve terminal activity. Enhances androgen receptor (AR)-mediated transcription. May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. May play a functional role in the cell filament networks. May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors., [UniProtKB, UniProtKB, UniProtKB]",
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        "secondary_ac_list": "A0A8M2B480",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003779 actin binding;GO:0005543 phospholipid binding;GO:0030276 clathrin binding;GO:0043325 phosphatidylinositol-3,4-bisphosphate binding;GO:0051015 actin filament binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0045202 synapse;GO:0030659 cytoplasmic vesicle membrane;GO:0030136 clathrin-coated vesicle;GO:0030864 cortical actin cytoskeleton",
        "go_biological_process": "GO:0001878 response to yeast;GO:0006351 DNA-templated transcription;GO:0006897 endocytosis;GO:0030154 cell differentiation;GO:0006915 apoptotic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "F1R6L2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "F1REK0_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1REK0",
                "type": "external"
            }
        ],
        "mass": 112708.0,
        "length": 1072,
        "protein_name": "3.2.1.3; Histone deacetylase complex subunit SAP130a",
        "gene_name": "sap130a",
        "organism": "Zebrafish",
        "refseq_name": "histone deacetylase complex subunit SAP130a",
        "refseq_ac": [
            {
                "id": "NP_001092247",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092247",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "sap130a; zgc:162722",
        "gene_names_refseq": "sap130a; zgc:162722",
        "protein_names_uniprotkb": "3.2.1.3; Histone deacetylase complex subunit SAP130a",
        "protein_names_refseq": "Sin3A-associated protein a; histone deacetylase complex subunit SAP130a",
        "tax_id": 7955,
        "disease": "congenital heart disease (Disease Ontology:DOID:1682); hypoplastic left heart syndrome (Disease Ontology:DOID:9955)",
        "pathway": " (dre:100073341)",
        "pathway_count": 1,
        "publication_count": 5,
        "publication_id_list": "25533962;26469318;27189481;28530678;37711853",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC142598.1, GFIL01034417.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505375, SAMEA3505378 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On Jun 25, 2025 this sequence version replaced NP_001092247.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 1,
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        "secondary_ac_list": "A0A8M1NEX8",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004339 glucan 1,4-alpha-glucosidase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0070822 Sin3-type complex",
        "go_biological_process": "GO:0021508 floor plate formation;GO:0003231 cardiac ventricle development;GO:0006351 DNA-templated transcription;GO:0007507 heart development;GO:0006355 regulation of DNA-templated transcription",
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        "kg_view_protein": true
    },
    {
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            {
                "id": "F1QWN1_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1QWN1",
                "type": "external"
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        ],
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        "protein_name": "Apoptosis-stimulating of p53 protein 2b isoform X1",
        "gene_name": "tp53bp2b",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "tp53bp2b; si:dkeyp-34c12.2",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Apoptosis-stimulating of p53 protein 2b isoform X1",
        "protein_names_refseq": "",
        "tax_id": 7955,
        "disease": "chromosome 1q41-q42 deletion syndrome (Disease Ontology:DOID:0060412)",
        "pathway": " (dre:568138)",
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        "publication_id_list": "15520368;24362258;25139857;28252024",
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            {
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            }
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        "gene_names_uniprotkb": "phactr4a; zgc:123224",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Phosphatase and actin regulator 4A",
        "protein_names_refseq": "",
        "tax_id": 7955,
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        "pathway": " (dre:569383)",
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        "publication_id_list": "20463905;23594743;24683187;26469318;27189481",
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        "function": "Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_biological_process": "GO:0048484 enteric nervous system development;GO:0061386 closure of optic fissure;GO:0043085 positive regulation of catalytic activity;GO:0030036 actin cytoskeleton organization;GO:0007266 Rho protein signal transduction",
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        "protein_name": "Cyclin-dependent kinase 10",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC092827.1, SRR32588728.10444255.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On or before Sep 27, 2016 this sequence version replaced XP_017209567.1, NP_001017622.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; Cdk10 has roles in vertebrate development and a critical function in neurogenesis by modulation of raf1a expression, [RefSeq, PubMed]; Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells). Involved in the regulation of actin cytoskeleton organization through the phosphorylation of actin dynamics regulators such as PKN2. Is a negative regulator of ciliogenesis through phosphorylation of PKN2 and promotion of RhoA signaling., [UniProtKB, UniProtKB]",
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            }
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        "protein_names_uniprotkb": "Transcription factor",
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        "disease": "mismatch repair cancer syndrome (Disease Ontology:DOID:0112182)",
        "pathway": " (dre:393749)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC059610.1, ERR4321680.680468.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH593111.1, EH541383.1, JBMGRA010000001.1, EH562533.1 and EH610421.1. On Sep 2, 2015 this sequence version replaced NP_957070.1., [RefSeq]",
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        "protein_name": "Dachshund b",
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            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_694488",
                "type": "external"
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        "gene_names_refseq": "dachb; zgc:136530",
        "protein_names_uniprotkb": "Dachshund b",
        "protein_names_refseq": "dachshund b",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:192122)",
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        "publication_id_list": "11850192;17035528;20869363;24150847;25556858;27189481;33248229;33449448;38492873",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01008238.1, GDQH01002885.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505375 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Jun 25, 2025 this sequence version replaced NP_694488.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Isolation of three zebrafish dachshund homologues and their expression in sensory organs, the central nervous system and pectoral fin buds, [RefSeq, PubMed]",
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                "id": "O57418_DANRE",
                "url": "https://www.uniprot.org/uniprot/O57418",
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        ],
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        "protein_name": "Paired box protein Pax-7a isoform PAX7C",
        "gene_name": "pax7a",
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        "refseq_name": "paired box protein Pax-7a isoform PAX7C",
        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571400",
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        "gene_names_refseq": "pax7a",
        "protein_names_uniprotkb": "Paired box protein Pax-7a isoform PAX7C",
        "protein_names_refseq": "paired box gene 7a; paired box homeotic gene 7a; paired box protein Pax-7a isoform PAX7C",
        "tax_id": 7955,
        "disease": "congenital myopathy 19 (Disease Ontology:DOID:0081351); prostate cancer (Disease Ontology:DOID:10283); alveolar rhabdomyosarcoma (Disease Ontology:DOID:4051)",
        "pathway": " (dre:30587)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "10357894;10801442;11861475;11922991;12091300;34473348;34831043;35356436;36346812;38542412",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: AF014368.1, GFIL01006739.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505389, SAMEA3505390 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
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        "go_molecular_function": "GO:0003677 DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0042060 wound healing;GO:0048066 developmental pigmentation;GO:0009653 anatomical structure morphogenesis;GO:0050938 regulation of xanthophore differentiation",
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    {
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        "uniprot_id": [
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        "protein_name": "Tyrosine-protein phosphatase",
        "gene_name": "ptpn4b",
        "organism": "Zebrafish",
        "refseq_name": "tyrosine-protein phosphatase non-receptor type 4b isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005174003",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174003",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ptpn4b; fi40g11; ptpn4a; si:rp71-1n18.2; wu:fi40g11",
        "gene_names_refseq": "fi40g11; ptpn4a; ptpn4b; si:rp71-1n18.2; wu:fi40g11",
        "protein_names_uniprotkb": "Tyrosine-protein phosphatase; 3.1.3.48",
        "protein_names_refseq": "tyrosine-protein phosphatase non-receptor type 4b isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:407634)",
        "pathway_count": 1,
        "publication_count": 5,
        "publication_id_list": "20838449;23974070;26469318;28252024;28814789",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 2,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 2,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
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        "reported_s_glycosites_with_glycan": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 2,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M2BLA0",
        "ec_number_list": [
            {
                "id": "3.1.3.16",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16",
                "type": "external"
            },
            {
                "id": "3.1.3.48",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48",
                "type": "external"
            },
            {
                "id": "3.1.3.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2",
                "type": "external"
            },
            {
                "id": "3.1.3.67",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67",
                "type": "external"
            },
            {
                "id": "3.1.3.27",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27",
                "type": "external"
            },
            {
                "id": "3.1.3.21",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0008092 cytoskeletal protein binding;GO:0004725 protein tyrosine phosphatase activity",
        "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005737 cytoplasm;GO:0009898 cytoplasmic side of plasma membrane",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.6,
        "record_id": "F1QFY3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q0P410-1",
        "uniprot_id": [
            {
                "id": "SAMTR_DANRE",
                "url": "https://www.uniprot.org/uniprot/Q0P410",
                "type": "external"
            }
        ],
        "mass": 44782.0,
        "length": 393,
        "protein_name": "S-adenosylmethionine sensor upstream of mTORC1",
        "gene_name": "samtor",
        "organism": "Zebrafish",
        "refseq_name": "S-adenosylmethionine sensor upstream of mTORC1",
        "refseq_ac": [
            {
                "id": "NP_001070615",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070615",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "samtor; BMT2; SAMTOR; bmt2; zgc:153606",
        "gene_names_refseq": "bmt2; samtor; zgc:153606",
        "protein_names_uniprotkb": "S-adenosylmethionine sensor upstream of mTORC1; 2.1.1.-; Probable methyltransferase BMT2 homolog",
        "protein_names_refseq": "S-adenosylmethionine sensor upstream of mTORC1; UPF0532 protein C7orf60 homolog; base methyltransferase of 25S rRNA 2 homolog; probable methyltransferase BMT2 homolog",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:558558)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC122347.1, EH583046.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA4476747, SAMEA4476762 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC122347.1. On Oct 11, 2006 this sequence version replaced XP_686881.1., [RefSeq]; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase., [UniProtKB, HAMAP, UniProtKB]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
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        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
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        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008168 methyltransferase activity;GO:1904047 S-adenosyl-L-methionine binding",
        "go_cellular_component": "",
        "go_biological_process": "GO:0032259 methylation;GO:0034198 cellular response to amino acid starvation;GO:1903432 regulation of TORC1 signaling",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "Q0P410-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1QK93-1",
        "uniprot_id": [
            {
                "id": "F1QK93_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1QK93",
                "type": "external"
            }
        ],
        "mass": 107107.0,
        "length": 964,
        "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
        "gene_name": "psmd1",
        "organism": "Zebrafish",
        "refseq_name": "26S proteasome non-ATPase regulatory subunit 1",
        "refseq_ac": [
            {
                "id": "NP_957478",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957478",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "psmd1; zgc:55818",
        "gene_names_refseq": "psmd1; zgc:55818",
        "protein_names_uniprotkb": "26S proteasome non-ATPase regulatory subunit 1",
        "protein_names_refseq": "26S proteasome non-ATPase regulatory subunit 1; proteasome (prosome, macropain) 26S subunit, non-ATPase, 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:554967);  (R-DRE-1169091);  (R-DRE-1234176);  (R-DRE-1236978);  (R-DRE-174084);  (R-DRE-174154);  (R-DRE-174178);  (R-DRE-174184);  (R-DRE-187577);  (R-DRE-195253);  (R-DRE-2467813);  (R-DRE-349425);  (R-DRE-350562);  (R-DRE-382556);  (R-DRE-450408);  (R-DRE-4608870);  (R-DRE-4641257);  (R-DRE-4641258);  (R-DRE-5358346);  (R-DRE-5610780);  (R-DRE-5610785);  (R-DRE-5632684);  (R-DRE-5658442);  (R-DRE-5668541);  (R-DRE-5687128);  (R-DRE-5689603);  (R-DRE-5689880);  (R-DRE-6798695);  (R-DRE-68867);  (R-DRE-68949);  (R-DRE-69017);  (R-DRE-69481);  (R-DRE-69601);  (R-DRE-75815);  (R-DRE-8852276);  (R-DRE-8854050);  (R-DRE-8939236);  (R-DRE-8939902);  (R-DRE-8941858);  (R-DRE-8948751);  (R-DRE-8951664);  (R-DRE-9755511);  (R-DRE-9762114);  (R-DRE-9766229);  (R-DRE-983168);  (R-DRE-9907900);  (R-DRE-9929491);  (R-DRE-9932298);  (R-DRE-9954709)",
        "pathway_count": 49,
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        "publication_id_list": "14718378;24714733;26469318;28252024;31515263;35831435;37256609",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC045463.1, GDQH01001975.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1, EH443001.1 and EH604198.1. On May 13, 2015 this sequence version replaced NP_957478.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
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        "predicted_c_glycosites": 0,
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        "mined_o_glycosites": 0,
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        "mined_s_glycosites": 0,
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        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
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        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A0R4IJ38;A0A8M1PFS1",
        "ec_number_list": [],
        "go_molecular_function": "GO:0030234 enzyme regulator activity",
        "go_cellular_component": "GO:0008540 proteasome regulatory particle, base subcomplex;GO:0034515 proteasome storage granule;GO:0005634 nucleus",
        "go_biological_process": "GO:0042176 regulation of protein catabolic process;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.8,
        "record_id": "F1QK93-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1R412-1",
        "uniprot_id": [
            {
                "id": "F1R412_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1R412",
                "type": "external"
            }
        ],
        "mass": 32642.0,
        "length": 284,
        "protein_name": "Tropomyosin 4a isoform X1",
        "gene_name": "tpm4a",
        "organism": "Zebrafish",
        "refseq_name": "tropomyosin 4a isoform X1",
        "refseq_ac": [
            {
                "id": "XP_017208599",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208599",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tpm4a; TPM4-1; tpm4; wu:fb06e07; zgc:103436; zgc:63909",
        "gene_names_refseq": "TPM4-1; tpm4a; tpm4; wu:fb06e07; zgc:103436; zgc:63909",
        "protein_names_uniprotkb": "Tropomyosin 4a isoform X1",
        "protein_names_refseq": "tropomyosin 4a isoform X1",
        "tax_id": 7955,
        "disease": "dilated cardiomyopathy (Disease Ontology:DOID:12930); blood platelet disease (Disease Ontology:DOID:2218)",
        "pathway": "",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M6YUW1",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003779 actin binding;GO:0051015 actin filament binding",
        "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005884 actin filament",
        "go_biological_process": "GO:0060047 heart contraction;GO:0055003 cardiac myofibril assembly;GO:0060048 cardiac muscle contraction;GO:0006936 muscle contraction;GO:0007015 actin filament organization",
        "synthesized_glycan_count": 0,
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        "record_type": "protein",
        "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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            {
                "id": "F1RBT2_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1RBT2",
                "type": "external"
            }
        ],
        "mass": 221363.0,
        "length": 1953,
        "protein_name": "Chromodomain-helicase-DNA-binding protein 4 isoform X1",
        "gene_name": "chd4b",
        "organism": "Zebrafish",
        "refseq_name": "chromodomain-helicase-DNA-binding protein 4 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_021322613",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322613",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "chd4b",
        "gene_names_refseq": "chd4b",
        "protein_names_uniprotkb": "Chromodomain-helicase-DNA-binding protein 4 isoform X1",
        "protein_names_refseq": "chromodomain-helicase-DNA-binding protein 4 isoform X1",
        "tax_id": 7955,
        "disease": "lymphoma (Disease Ontology:DOID:0060058); left ventricular noncompaction (Disease Ontology:DOID:0060480); Sifrim-Hitz-Weiss syndrome (Disease Ontology:DOID:0070529); lung cancer (Disease Ontology:DOID:1324); rectum cancer (Disease Ontology:DOID:1993); colon adenocarcinoma (Disease Ontology:DOID:234); lung adenocarcinoma (Disease Ontology:DOID:3910); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256)",
        "pathway": " (dre:560622);  (R-DRE-3214815);  (R-DRE-6804758);  (R-DRE-8943724);  (R-DRE-9031628);  (R-DRE-9937850);  (R-DRE-9940465);  (R-DRE-9940951)",
        "pathway_count": 8,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M9P8D7",
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        ],
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        "refseq_ac": [
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        ],
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        "disease": "autosomal dominant nocturnal frontal lobe epilepsy 4 (Disease Ontology:DOID:0060685); asthma (Disease Ontology:DOID:2841)",
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        "go_cellular_component": "GO:0045211 postsynaptic membrane;GO:0005886 plasma membrane;GO:0005892 acetylcholine-gated channel complex;GO:0045202 synapse;GO:0043005 neuron projection",
        "go_biological_process": "GO:0007271 synaptic transmission, cholinergic;GO:0007274 neuromuscular synaptic transmission;GO:0035094 response to nicotine;GO:0095500 acetylcholine receptor signaling pathway;GO:0034220 monoatomic ion transmembrane transport",
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        "length": 1103,
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        "refseq_ac": [
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        "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 7 isoform X4",
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        "go_biological_process": "GO:1904888 cranial skeletal system development;GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0031647 regulation of protein stability",
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        ],
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        "length": 287,
        "protein_name": "E3 ubiquitin-protein ligase CHIP",
        "gene_name": "stub1",
        "organism": "Zebrafish",
        "refseq_name": "E3 ubiquitin-protein ligase CHIP",
        "refseq_ac": [
            {
                "id": "NP_955968",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_955968",
                "type": "external"
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        "gene_names_uniprotkb": "stub1; wu:fc22f04; zgc:56076",
        "gene_names_refseq": "stub1; wu:fc22f04; zgc:56076",
        "protein_names_uniprotkb": "E3 ubiquitin-protein ligase CHIP; 2.3.2.27; RING-type E3 ubiquitin transferase CHIP; STIP1 homology and U box-containing protein 1",
        "protein_names_refseq": "CHIP; E3 ubiquitin-protein ligase CHIP",
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        "disease": "autosomal recessive spinocerebellar ataxia 16 (Disease Ontology:DOID:0080029); cerebellar ataxia type 48 (Disease Ontology:DOID:0111746); Duchenne muscular dystrophy (Disease Ontology:DOID:11723)",
        "pathway": "",
        "pathway_count": 0,
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588735.1590946.1, SRR32588730.21969347.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1 and EH457730.1. On or before Jan 29, 2016 this sequence version replaced XP_009295927.1, NP_955968.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; TCF12 haploinsufficiency causes autosomal dominant Kallmann syndrome and reveals network-level interactions between causal loci., [RefSeq, PubMed]",
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        "go_molecular_function": "GO:0061630 ubiquitin protein ligase activity",
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        "mass": 77416.0,
        "length": 697,
        "protein_name": "Sodium/hydrogen exchanger",
        "gene_name": "slc9a6a",
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        "refseq_name": "sodium/hydrogen exchanger 6a precursor",
        "refseq_ac": [
            {
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                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "slc9a6a; fv47b07; wu:fv47b07; zgc:163055",
        "gene_names_refseq": "fv47b07; slc9a6a; wu:fv47b07; zgc:163055",
        "protein_names_uniprotkb": "Sodium/hydrogen exchanger",
        "protein_names_refseq": "sodium/hydrogen exchanger 6a precursor; solute carrier family 9 (sodium/hydrogen exchanger), member 6a; solute carrier family 9 member A6; solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6a",
        "tax_id": 7955,
        "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); Christianson syndrome (Disease Ontology:DOID:0060825)",
        "pathway": " (dre:792983)",
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        "function": "##Evidence-Data-START## RNAseq introns :: partial sample support SAMEA3505376, SAMEA3505383 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX511227.7. On Dec 19, 2008 this sequence version replaced NP_001091726.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
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        "go_biological_process": "GO:0006885 regulation of pH",
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        "gene_name": "cltca",
        "organism": "Zebrafish",
        "refseq_name": "clathrin, heavy chain a (Hc)",
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        "gene_names_uniprotkb": "cltca; cb1033; cltc; wu:fc03e11; wu:fc49a11; wu:fd07f02",
        "gene_names_refseq": "cb1033; cltca; cltc; wu:fc03e11; wu:fc49a11; wu:fd07f02",
        "protein_names_uniprotkb": "Clathrin heavy chain",
        "protein_names_refseq": "clathrin, heavy chain a (Hc); clathrin, heavy polypeptide a (Hc)",
        "tax_id": 7955,
        "disease": "autosomal dominant intellectual developmental disorder 56 (Disease Ontology:DOID:0080226)",
        "pathway": " (dre:323579)",
        "pathway_count": 1,
        "publication_count": 9,
        "publication_id_list": "15520368;16109975;19240126;22056673;22898784;23460678;28252024;30224808;36078102",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: AY648777.1, BC163714.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000010.1. On Apr 15, 2009 this sequence version replaced NP_001005391.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments., [RefSeq]; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 1,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1N2E2",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005198 structural molecule activity;GO:0032051 clathrin light chain binding",
        "go_cellular_component": "GO:0030130 clathrin coat of trans-Golgi network vesicle;GO:0071439 clathrin complex;GO:0030132 clathrin coat of coated pit",
        "go_biological_process": "GO:0006886 intracellular protein transport;GO:0016192 vesicle-mediated transport",
        "synthesized_glycan_count": 0,
        "hit_score": 1.0,
        "record_id": "F1R966-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F6NLJ7-1",
        "uniprot_id": [
            {
                "id": "F6NLJ7_DANRE",
                "url": "https://www.uniprot.org/uniprot/F6NLJ7",
                "type": "external"
            }
        ],
        "mass": 80407.0,
        "length": 703,
        "protein_name": "FACT complex subunit SSRP1",
        "gene_name": "ssrp1b",
        "organism": "Zebrafish",
        "refseq_name": "FACT complex subunit SSRP1",
        "refseq_ac": [
            {
                "id": "XP_001923156",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001923156",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ssrp1b",
        "gene_names_refseq": "ssrp1b",
        "protein_names_uniprotkb": "FACT complex subunit SSRP1",
        "protein_names_refseq": "FACT complex subunit SSRP1",
        "tax_id": 7955,
        "disease": "cancer (Disease Ontology:DOID:162)",
        "pathway": " (dre:449949)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001923156.2. COMPLETENESS: full length., [RefSeq]; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. Binds specifically to double-stranded DNA., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 1,
        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8M1QKV2",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003677 DNA binding",
        "go_cellular_component": "GO:0005730 nucleolus;GO:0005694 chromosome",
        "go_biological_process": "GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0006260 DNA replication",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "F6NLJ7-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1RBN2-1",
        "uniprot_id": [
            {
                "id": "SPAG1_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1RBN2",
                "type": "external"
            }
        ],
        "mass": 46984.0,
        "length": 427,
        "protein_name": "Sperm-associated antigen 1A",
        "gene_name": "spag1a",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "spag1a; cb1089; spag1; wu:fj78g10",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Sperm-associated antigen 1A",
        "protein_names_refseq": "",
        "tax_id": 7955,
        "disease": "primary ciliary dyskinesia 28 (Disease Ontology:DOID:0110607)",
        "pathway": " (dre:564953)",
        "pathway_count": 1,
        "publication_count": 8,
        "publication_id_list": "23594743;24055112;26469318;27156127;28252024;31352104;33577748;40044042",
        "class_list": "",
        "function": "May play a role in the cytoplasmic assembly and/or trafficking of the axonemal dynein arms., [UniProtKB, PubMed]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 1,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 1,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 1,
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        "reported_fully_resolved_glycans": 1,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
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        "missing_score": 0,
        "biomarker_type": "",
        "glycan_count": 1,
        "disease_count": 1,
        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A4QNV4",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0120293 dynein axonemal particle",
        "go_biological_process": "GO:0070286 axonemal dynein complex assembly",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "F1RBN2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0100000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q01704-1",
        "uniprot_id": [
            {
                "id": "MSXD_DANRE",
                "url": "https://www.uniprot.org/uniprot/Q01704",
                "type": "external"
            }
        ],
        "mass": 25867.0,
        "length": 226,
        "protein_name": "Homeobox protein MSH-D",
        "gene_name": "msx2b; msxd",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "msx2b; msxd; msh-D; msh-d; mshD; msxd",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Homeobox protein MSH-D",
        "protein_names_refseq": "",
        "tax_id": 7955,
        "disease": "parietal foramina (Disease Ontology:DOID:0060285); craniosynostosis 2 (Disease Ontology:DOID:0061009); hypertension (Disease Ontology:DOID:10763); craniosynostosis (Disease Ontology:DOID:2340)",
        "pathway": " (dre:30531)",
        "pathway_count": 1,
        "publication_count": 11,
        "publication_id_list": "1352984;31262711;32812127;34842743;36891971;38527087;7768177;8617510;8903357;8978059;9335141",
        "class_list": "",
        "function": "Involved in the development of the inner ear., [UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "predicted_c_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "total_reported_s_glycosites": 0,
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        "total_o_glycosites": 0,
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        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 4,
        "glyco_site_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0048598 embryonic morphogenesis;GO:0043049 otic placode formation",
        "synthesized_glycan_count": 0,
        "hit_score": 1.2,
        "record_id": "Q01704-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q05AM5-1",
        "uniprot_id": [
            {
                "id": "ELP2_DANRE",
                "url": "https://www.uniprot.org/uniprot/Q05AM5",
                "type": "external"
            }
        ],
        "mass": 90083.0,
        "length": 821,
        "protein_name": "Elongator complex protein 2",
        "gene_name": "elp2",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "elp2; si:dkey-190l1.1; zgc:153559",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Elongator complex protein 2; ELP2",
        "protein_names_refseq": "",
        "tax_id": 7955,
        "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); autosomal recessive intellectual developmental disorder 58 (Disease Ontology:DOID:0081220); intellectual disability (Disease Ontology:DOID:1059)",
        "pathway": " (dre:560338)",
        "pathway_count": 1,
        "publication_count": 4,
        "publication_id_list": "15520368;23594743;26469318;31053140",
        "class_list": "",
        "function": "Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 3,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "Q1LUN8",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0033588 elongator holoenzyme complex",
        "go_biological_process": "GO:0002098 tRNA wobble uridine modification",
        "synthesized_glycan_count": 0,
        "hit_score": 0.5,
        "record_id": "Q05AM5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F8W4B9-1",
        "uniprot_id": [
            {
                "id": "F8W4B9_DANRE",
                "url": "https://www.uniprot.org/uniprot/F8W4B9",
                "type": "external"
            }
        ],
        "mass": 54642.0,
        "length": 485,
        "protein_name": "E3 SUMO-protein ligase PIAS4b isoform 1",
        "gene_name": "pias4b",
        "organism": "Zebrafish",
        "refseq_name": "E3 SUMO-protein ligase PIAS4b isoform 1",
        "refseq_ac": [
            {
                "id": "NP_956637",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956637",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pias4b; pias4l; wu:fi26h11; zgc:63923",
        "gene_names_refseq": "pias4b; pias4l; wu:fi26h11; zgc:63923",
        "protein_names_uniprotkb": "E3 SUMO-protein ligase PIAS4b isoform 1",
        "protein_names_refseq": "E3 SUMO-protein ligase PIAS4b isoform 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:393314)",
        "pathway_count": 1,
        "publication_count": 4,
        "publication_id_list": "22345667;25434820;26469318;27189481",
        "class_list": "",
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        "predicted_glycosites": 1,
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        "total_reported_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A8N1TYF8",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016740 transferase activity;GO:0016874 ligase activity;GO:0061665 SUMO ligase activity;GO:0003712 transcription coregulator activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin",
        "go_biological_process": "GO:0016925 protein sumoylation;GO:0060255 regulation of macromolecule metabolic process;GO:0006357 regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
        "hit_score": 0.5,
        "record_id": "F8W4B9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "P31367-1",
        "uniprot_id": [
            {
                "id": "PO6F1_DANRE",
                "url": "https://www.uniprot.org/uniprot/P31367",
                "type": "external"
            }
        ],
        "mass": 63124.0,
        "length": 610,
        "protein_name": "POU domain, class 6, transcription factor 1",
        "gene_name": "pou6f1",
        "organism": "Zebrafish",
        "refseq_name": "POU domain, class 6, transcription factor 1",
        "refseq_ac": [
            {
                "id": "NP_571188",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_571188",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pou6f1; pou[c]; pouc",
        "gene_names_refseq": "pou6f1; pou[c]; pouc",
        "protein_names_uniprotkb": "POU domain, class 6, transcription factor 1; POU domain protein C; POU[C]; ZfPOU[C]",
        "protein_names_refseq": "POU domain gene C; POU domain protein C; POU domain, class 6, transcription factor 1; ZFPOU[C]",
        "tax_id": 7955,
        "disease": "lung adenocarcinoma (Disease Ontology:DOID:3910)",
        "pathway": " (dre:30334)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "30444277;8441661",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: X68432.1, BC162146.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X68432.1., [RefSeq]; Transcription factor that binds with high affinity to the motif 5'-TAATGARAT-3'., [UniProtKB, PubMed]; We find that pouC is a multi-functional transcriptional regulator containing separable activation, repression, protein-protein interaction, and DNA binding domains. Using zebrafish heart development as a model system, we demonstrate that pouC knockdown impairs cardiac morphogenesis and affects cardiovascular function. We also find that levels of pouC expression must be fine-tuned to enable proper heart formation., [RefSeq, PubMed]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
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        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "B3DFR1",
        "ec_number_list": [],
        "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:1905222 atrioventricular canal morphogenesis",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "P31367-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "Q0P426-1",
        "uniprot_id": [
            {
                "id": "SKA2_DANRE",
                "url": "https://www.uniprot.org/uniprot/Q0P426",
                "type": "external"
            }
        ],
        "mass": 25296.0,
        "length": 226,
        "protein_name": "SKA complex subunit 2",
        "gene_name": "ska2",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "ska2; fam33a; im:7140390",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "SKA complex subunit 2; Protein FAM33A; Spindle and kinetochore-associated protein 2",
        "protein_names_refseq": "",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:449942);  (R-DRE-141430);  (R-DRE-141444);  (R-DRE-2467813);  (R-DRE-2500257);  (R-DRE-5663220)",
        "pathway_count": 6,
        "publication_count": 2,
        "publication_id_list": "12477932;21873635",
        "class_list": "",
        "function": "Component of the SKA complex, a microtubule plus end-binding complex of the outer kinetochore that stabilizes spindle microtubule-kinetochore attachments, promotes alignment of chromosomes at the mitotic spindle equator (chromosome congression) and assists suppression of the spindle assembly checkpoint. Kinetochores, consisting of a centromere-associated inner segment and a microtubule-contacting outer segment, play a crucial role in chromosome segregation by mediating the physical connection between centromeric DNA and spindle microtubules. The outer kinetochore is made up of the ten-subunit KMN network complex, comprising the MIS12, NDC80 and KNL1 complexes, and auxiliary microtubule-associated components such as the SKA complex; together they connect the outer kinetochore with the inner kinetochore, bind microtubules, and mediate interactions with mitotic checkpoint proteins that delay anaphase until chromosomes are bioriented on the spindle. The SKA complex is loaded onto bioriented kinetochores and it facilitates chromosome congression by stabilizing microtubules together with MAPRE1, and end-on attachment of the NDC80 complex to depolymerizing spindle microtubules, thereby assisting the poleward-moving kinetochore in withstanding microtubule pulling forces. The complex associates with dynamic microtubule plus-ends and can track both depolymerizing and elongating microtubules. The complex recruits protein phosphatase 1 (PP1) to the kinetochore in prometaphase and metaphase, to oppose spindle assembly checkpoint signaling and promote the onset of anaphase. Binds directly to microtubules; but with a much lower affinity than SKA1 (By similarity). During meiosis the SKA complex stabilizes the meiotic spindle and is required for its migration to the cortex (By similarity)., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008017 microtubule binding",
        "go_cellular_component": "GO:0005876 spindle microtubule;GO:0072687 meiotic spindle;GO:0000940 outer kinetochore",
        "go_biological_process": "GO:0031110 regulation of microtubule polymerization or depolymerization;GO:0051315 attachment of mitotic spindle microtubules to kinetochore;GO:0000278 mitotic cell cycle;GO:0007059 chromosome segregation;GO:0051301 cell division",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "Q0P426-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1RDM5-1",
        "uniprot_id": [
            {
                "id": "AMER1_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1RDM5",
                "type": "external"
            }
        ],
        "mass": 102526.0,
        "length": 930,
        "protein_name": "APC membrane recruitment protein 1",
        "gene_name": "amer1",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "amer1; fam123b; wtx",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "APC membrane recruitment protein 1; Amer1; Protein FAM123B",
        "protein_names_refseq": "",
        "tax_id": 7955,
        "disease": "osteopathia striata with cranial sclerosis (Disease Ontology:DOID:0060886); colorectal cancer (Disease Ontology:DOID:9256)",
        "pathway": " (dre:100885784);  (R-DRE-195253);  (R-DRE-196299)",
        "pathway_count": 3,
        "publication_count": 6,
        "publication_id_list": "17510365;23594743;25869932;27130213;31290212;38255806",
        "class_list": "",
        "function": "Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex. Acts both as a positive and negative regulator of the Wnt signaling pathway, depending on the context (By similarity)., [UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A9JTD0",
        "ec_number_list": [],
        "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0008013 beta-catenin binding;GO:0008289 lipid binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0014032 neural crest cell development;GO:0016055 Wnt signaling pathway;GO:0030178 negative regulation of Wnt signaling pathway;GO:0060828 regulation of canonical Wnt signaling pathway",
        "synthesized_glycan_count": 0,
        "hit_score": 0.7,
        "record_id": "F1RDM5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "P0CAX4-1",
        "uniprot_id": [
            {
                "id": "AUGNB_DANRE",
                "url": "https://www.uniprot.org/uniprot/P0CAX4",
                "type": "external"
            }
        ],
        "mass": 16872.0,
        "length": 144,
        "protein_name": "Augurin-B",
        "gene_name": "ecrg4b",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "ecrg4b; im:7256818",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Augurin-B; Esophageal cancer-related gene 4-B protein homolog",
        "protein_names_refseq": "",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:793804)",
        "pathway_count": 1,
        "publication_count": 7,
        "publication_id_list": "21349154;23594743;26559940;27189481;29283341;29877572;32455839",
        "class_list": "",
        "function": "Probable hormone (By similarity). Required for the proper formation of the central nervous system by attenuating cell proliferation during development (By similarity)., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "F1QPI8",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0016324 apical plasma membrane;GO:0005576 extracellular region",
        "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:0042127 regulation of cell population proliferation;GO:0007417 central nervous system development;GO:0009611 response to wounding;GO:0031145 anaphase-promoting complex-dependent catabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.8,
        "record_id": "P0CAX4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1R6N4-1",
        "uniprot_id": [
            {
                "id": "ECHD1_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1R6N4",
                "type": "external"
            }
        ],
        "mass": 32326.0,
        "length": 302,
        "protein_name": "Ethylmalonyl-CoA decarboxylase",
        "gene_name": "echdc1",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "echdc1; MMCD; zgc:110060",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Ethylmalonyl-CoA decarboxylase; 4.1.1.94; Enoyl-CoA hydratase domain-containing protein 1; MMCD; Methylmalonyl-CoA decarboxylase",
        "protein_names_refseq": "",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:553585)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "23594743;27189481",
        "class_list": "",
        "function": "Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Acts preferentially on (S)-ethylmalonyl-CoA but also has some activity on the (R)-isomer. Also has methylmalonyl-CoA decarboxylase activity at lower level., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "total_reported_s_glycosites": 0,
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        "reported_phosphosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "4.1.1.94",
                "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.94",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004492 methyl/ethyl malonyl-CoA decarboxylase activity;GO:0016831 carboxy-lyase activity",
        "go_cellular_component": "GO:0005829 cytosol",
        "go_biological_process": "GO:0006635 fatty acid beta-oxidation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "F1R6N4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "F1QJN9-1",
        "uniprot_id": [
            {
                "id": "F1QJN9_DANRE",
                "url": "https://www.uniprot.org/uniprot/F1QJN9",
                "type": "external"
            }
        ],
        "mass": 46670.0,
        "length": 416,
        "protein_name": "Carboxypeptidase B",
        "gene_name": "cpb1",
        "organism": "Zebrafish",
        "refseq_name": "carboxypeptidase B isoform 1 precursor",
        "refseq_ac": [
            {
                "id": "NP_001315354",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315354",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cpb1; wu:fb60d07; wu:fb69b08",
        "gene_names_refseq": "cpb1; wu:fb60d07; wu:fb69b08",
        "protein_names_uniprotkb": "Carboxypeptidase B; 3.4.17.2",
        "protein_names_refseq": "carboxypeptidase B isoform 1 precursor; zte141",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:322412);  (R-DRE-2022377)",
        "pathway_count": 2,
        "publication_count": 10,
        "publication_id_list": "16109975;18335061;18618001;19200601;20885977;33377648;33725575;33757938;34619175;35111746",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01007012.1, GDQH01000111.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505392, SAMEA4476736 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1, BC067637.1 and EE688842.1. On Jun 16, 2016 this sequence version replaced XP_005162544.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_n_glycosites": 0,
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        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0A0R4ILM4;A0A8M1P961",
        "ec_number_list": [
            {
                "id": "3.4.17.20",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.17.20",
                "type": "external"
            },
            {
                "id": "3.4.17.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.17.2",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004181 metallocarboxypeptidase activity",
        "go_cellular_component": "GO:0005615 extracellular space;GO:0031410 cytoplasmic vesicle",
        "go_biological_process": "GO:0006508 proteolysis;GO:0071466 cellular response to xenobiotic stimulus",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "F1QJN9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "P51047-1",
        "uniprot_id": [
            {
                "id": "MR1AL_DANRE",
                "url": "https://www.uniprot.org/uniprot/P51047",
                "type": "external"
            }
        ],
        "mass": 17634.0,
        "length": 152,
        "protein_name": "Melatonin receptor type 1A-like",
        "gene_name": "mtnr1al",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "mtnr1al; mel1a2; mel1a; mtnr1a",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Melatonin receptor type 1A-like; Mel-1A-R-like; Mel1a receptor-like; Melatonin receptor Mel1a Z1.4; zMel1a-2",
        "protein_names_refseq": "",
        "tax_id": 7955,
        "disease": "Huntington's disease (Disease Ontology:DOID:12858); type 2 diabetes mellitus (Disease Ontology:DOID:9352)",
        "pathway": " (dre:30660)",
        "pathway_count": 1,
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        "publication_id_list": "17622340;21840306;26303298;28318435;33071966;34119649;37354122;7576645",
        "class_list": "",
        "function": "High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "protein_names_uniprotkb": "Cyclin-K",
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        "pathway": " (dre:569432);  (R-DRE-674695);  (R-DRE-6796648);  (R-DRE-6807505);  (R-DRE-75955)",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200294",
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        "disease": "colorectal carcinoma (Disease Ontology:DOID:0080199); hydrocephalus (Disease Ontology:DOID:10908); renal cell carcinoma (Disease Ontology:DOID:4450); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256)",
        "pathway": " (dre:403020);  (R-DRE-3214858);  (R-DRE-8939243);  (R-DRE-9933937);  (R-DRE-9933939);  (R-DRE-9933946);  (R-DRE-9933947)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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            {
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        "gene_names_refseq": "eno4; zgc:153973",
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            {
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        "protein_names_refseq": "dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase isoform X1",
        "tax_id": 7955,
        "disease": "congenital disorder of glycosylation type I (Disease Ontology:DOID:0050570); congenital disorder of glycosylation Ic (Disease Ontology:DOID:0080555)",
        "pathway": " (dre:445327)",
        "pathway_count": 1,
        "publication_count": 4,
        "publication_id_list": "18335061;23228892;26469318;27189481",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the first glucose residue from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide intermediate Man(9)GlcNAc(2)-PP-Dol to produce Glc(1)Man(9)GlcNAc(2)-PP-Dol. Glc(1)Man(9)GlcNAc(2)-PP-Dol is a substrate for ALG8, the following enzyme in the biosynthetic pathway., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
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        "reported_n_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
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        "total_n_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
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        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 2,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "2.4.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0042281 dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity;GO:0046527 glucosyltransferase activity",
        "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0006488 dolichol-linked oligosaccharide biosynthetic process;GO:0006487 protein N-linked glycosylation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.5,
        "record_id": "A0AC58JR12-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AC58JQD6-1",
        "uniprot_id": [
            {
                "id": "A0AC58JQD6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AC58JQD6",
                "type": "external"
            }
        ],
        "mass": 497067.0,
        "length": 4302,
        "protein_name": "Pericentrin isoform X1",
        "gene_name": "pcnt",
        "organism": "Zebrafish",
        "refseq_name": "pericentrin isoform X1",
        "refseq_ac": [
            {
                "id": "XP_073808699",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073808699",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pcnt; fc85c01; sb:cb754; si:ch211-245b3.1; wu:fc85c01",
        "gene_names_refseq": "fc85c01; pcnt; sb:cb754; si:ch211-245b3.1; wu:fc85c01",
        "protein_names_uniprotkb": "Pericentrin isoform X1",
        "protein_names_refseq": "pericentrin isoform X1",
        "tax_id": 7955,
        "disease": "microcephalic osteodysplastic primordial dwarfism type II (Disease Ontology:DOID:0060609); Down syndrome (Disease Ontology:DOID:14250)",
        "pathway": " (dre:325536)",
        "pathway_count": 1,
        "publication_count": 7,
        "publication_id_list": "25445019;26247711;26469318;28252024;29708497;34455394;35304423",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003677 DNA binding",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome",
        "go_biological_process": "GO:0007165 signal transduction;GO:0007020 microtubule nucleation;GO:0007052 mitotic spindle organization",
        "synthesized_glycan_count": 0,
        "hit_score": 0.8,
        "record_id": "A0AC58JQD6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.001000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AC58JRS4-1",
        "uniprot_id": [
            {
                "id": "A0AC58JRS4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AC58JRS4",
                "type": "external"
            }
        ],
        "mass": 128333.0,
        "length": 1155,
        "protein_name": "ubiquitinyl hydrolase 1",
        "gene_name": "usp43a",
        "organism": "Zebrafish",
        "refseq_name": "ubiquitin carboxyl-terminal hydrolase 43a isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001428971",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428971",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "usp43a; si:ch211-57c18.1",
        "gene_names_refseq": "si:ch211-57c18.1; usp43a",
        "protein_names_uniprotkb": "ubiquitinyl hydrolase 1; 3.4.19.12",
        "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 43a isoform 1; usp43",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:563983)",
        "pathway_count": 1,
        "publication_count": 1,
        "publication_id_list": "20040115",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588714.37176010.1, SRR26395039.1067717.1 [ECO:0000332] RNAseq introns :: partial sample support SAMEA3505370, SAMEA3505372 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On Jul 21, 2025 this sequence version replaced XP_073809189.1., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
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        "missing_score": 10000,
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        "ec_number_list": [],
        "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity;GO:0016787 hydrolase activity",
        "go_cellular_component": "",
        "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination",
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        "hit_score": 0.2,
        "record_id": "A0AC58JRS4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AC58JQK6-1",
        "uniprot_id": [
            {
                "id": "A0AC58JQK6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AC58JQK6",
                "type": "external"
            }
        ],
        "mass": 80059.0,
        "length": 731,
        "protein_name": "Double-stranded RNA-binding protein Staufen homolog 1",
        "gene_name": "stau1",
        "organism": "Zebrafish",
        "refseq_name": "double-stranded RNA-binding protein Staufen homolog 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_073808726",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073808726",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "stau1; fi67e05; wu:fi67e05; zgc:77271",
        "gene_names_refseq": "fi67e05; stau1; wu:fi67e05; zgc:77271",
        "protein_names_uniprotkb": "Double-stranded RNA-binding protein Staufen homolog 1",
        "protein_names_refseq": "double-stranded RNA-binding protein Staufen homolog 1 isoform X1",
        "tax_id": 7955,
        "disease": "atherosclerosis (Disease Ontology:DOID:1936)",
        "pathway": " (dre:334440)",
        "pathway_count": 1,
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        "publication_id_list": "15567725;16513105;28252024;30103945",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
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        "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0003725 double-stranded RNA binding",
        "go_cellular_component": "GO:0005791 rough endoplasmic reticulum;GO:0005886 plasma membrane;GO:0043025 neuronal cell body;GO:0032839 dendrite cytoplasm;GO:0043005 neuron projection",
        "go_biological_process": "GO:0007281 germ cell development;GO:0035418 protein localization to synapse;GO:0008298 intracellular mRNA localization;GO:0098964 anterograde dendritic transport of messenger ribonucleoprotein complex",
        "synthesized_glycan_count": 0,
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        "record_id": "A0AC58JQK6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AC58JRW0-1",
        "uniprot_id": [
            {
                "id": "A0AC58JRW0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AC58JRW0",
                "type": "external"
            }
        ],
        "mass": 42918.0,
        "length": 384,
        "protein_name": "Deoxynucleotidyltransferase terminal-interacting protein 1",
        "gene_name": "ube2c",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "ube2c; im:7137135; zgc:123190",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Deoxynucleotidyltransferase terminal-interacting protein 1; (E3-independent) E2 ubiquitin-conjugating enzyme C; 2.3.2.23; 2.3.2.24; E2 ubiquitin-conjugating enzyme C; Terminal deoxynucleotidyltransferase-interacting factor 1; Ubiquitin carrier protein C; Ubiquitin-conjugating enzyme E2 C; Ubiquitin-protein ligase C",
        "protein_names_refseq": "",
        "tax_id": 7955,
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        "function": "Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit., [UniProtKB, UniProtKB]; Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "mined_o_glycosites": 0,
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        "mined_s_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "ec_number_list": [],
        "go_molecular_function": "GO:0003677 DNA binding;GO:0031491 nucleosome binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58JRW0-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AC58JQ07-1",
        "uniprot_id": [
            {
                "id": "A0AC58JQ07_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AC58JQ07",
                "type": "external"
            }
        ],
        "mass": 18694.0,
        "length": 169,
        "protein_name": "MyoD family inhibitor domain-containing protein 2 isoform X1",
        "gene_name": "mdfic2",
        "organism": "Zebrafish",
        "refseq_name": "myoD family inhibitor domain-containing protein 2 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_073808568",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073808568",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mdfic2; si:dkey-58f6.2",
        "gene_names_refseq": "mdfic2; si:dkey-58f6.2",
        "protein_names_uniprotkb": "MyoD family inhibitor domain-containing protein 2 isoform X1",
        "protein_names_refseq": "myoD family inhibitor domain-containing protein 2 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:107990272)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12",
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            },
            {
                "id": "2.7.11.39",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39",
                "type": "external"
            },
            {
                "id": "2.7.11.11",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11",
                "type": "external"
            },
            {
                "id": "2.7.1.153",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153",
                "type": "external"
            },
            {
                "id": "2.7.1.137",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137",
                "type": "external"
            },
            {
                "id": "2.7.1.154",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154",
                "type": "external"
            },
            {
                "id": "2.7.11.26",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26",
                "type": "external"
            },
            {
                "id": "2.7.11.31",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0016301 kinase activity",
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        "go_biological_process": "",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AC58JQ29-1",
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            {
                "id": "A0AC58JQ29_DANRE",
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            }
        ],
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        "length": 1035,
        "protein_name": "Ubiquitin carboxyl-terminal hydrolase 38 isoform X2",
        "gene_name": "usp38",
        "organism": "Zebrafish",
        "refseq_name": "ubiquitin carboxyl-terminal hydrolase 38 isoform X2",
        "refseq_ac": [
            {
                "id": "XP_073808597",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073808597",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "usp38",
        "gene_names_refseq": "usp38",
        "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 38 isoform X2",
        "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 38 isoform X2",
        "tax_id": 7955,
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        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "record_id": "A0AC58JQ29-1",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AC58JQA1-1",
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            {
                "id": "A0AC58JQA1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AC58JQA1",
                "type": "external"
            }
        ],
        "mass": 33871.0,
        "length": 302,
        "protein_name": "Nephronectin isoform X1",
        "gene_name": "si:ch211-194g2.4",
        "organism": "Zebrafish",
        "refseq_name": "nephronectin isoform X1",
        "refseq_ac": [
            {
                "id": "XP_073808656",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073808656",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch211-194g2.4",
        "gene_names_refseq": "si:ch211-194g2.4",
        "protein_names_uniprotkb": "Nephronectin isoform X1",
        "protein_names_refseq": "nephronectin isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "ec_number_list": [],
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        "record_id": "A0AC58JQA1-1",
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    {
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            {
                "id": "A0AC58JQB7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AC58JQB7",
                "type": "external"
            }
        ],
        "mass": 55504.0,
        "length": 485,
        "protein_name": "Lupus La protein isoform X1",
        "gene_name": "ssb",
        "organism": "Zebrafish",
        "refseq_name": "lupus La protein isoform X1",
        "refseq_ac": [
            {
                "id": "XP_073808680",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073808680",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ssb; wu:fb17f11; zgc:55588",
        "gene_names_refseq": "ssb; wu:fb17f11; zgc:55588",
        "protein_names_uniprotkb": "Lupus La protein isoform X1",
        "protein_names_refseq": "lupus La protein isoform X1",
        "tax_id": 7955,
        "disease": "",
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        "pathway_count": 0,
        "publication_count": 10,
        "publication_id_list": "16109975;22411201;23615277;24198278;26235539;26469318;27189481;28252024;29145093;33705730",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0003729 mRNA binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0010494 cytoplasmic stress granule;GO:1990904 ribonucleoprotein complex",
        "go_biological_process": "GO:0008033 tRNA processing;GO:0045727 positive regulation of translation",
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    },
    {
        "uniprot_canonical_ac": "A0AC58JQE1-1",
        "uniprot_id": [
            {
                "id": "A0AC58JQE1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AC58JQE1",
                "type": "external"
            }
        ],
        "mass": 39427.0,
        "length": 347,
        "protein_name": "UDP-D-glucose 4,6-dehydratase",
        "gene_name": "tgds",
        "organism": "Zebrafish",
        "refseq_name": "dTDP-D-glucose 4,6-dehydratase isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001428622",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428622",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tgds; wu:fi14g09; zgc:56498",
        "gene_names_refseq": "tgds; wu:fi14g09; zgc:56498",
        "protein_names_uniprotkb": "UDP-D-glucose 4,6-dehydratase; dTDP-D-glucose 4,6-dehydratase",
        "protein_names_refseq": "dTDP-D-glucose 4,6-dehydratase isoform 1; dTDP-D-glucose 4,6-dehydratase",
        "tax_id": 7955,
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        "publication_id_list": "12477932",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588733.1146902.1, SRR32588728.20174960.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On Jun 26, 2025 this sequence version replaced XP_073808708.1., [RefSeq]; UTP-glucose 4,6-dehydratase that converts UDP-glucose into UDP-4-keto-6-deoxyglucose, and which is required for glycosaminoglycan biosynthesis and skeletal development. UDP-4-keto-6-deoxyglucose is a mimic of the reaction intermediate of UXS1 and acts as an enzyme-rescue metabolite to promote the completion of UXS1 catalytic cycle when NAD(+) levels are low. Under low NAD(+) conditions, UXS1 forms an inactive UDP-4-ketoxylose intermediate bound to NADH, impairing the synthesis of specific glycans that are essential for skeletal development. UDP-4-keto-6-deoxyglucose is used by the inactive NADH-bound UXS1 to produce UDP-6-deoxyglucose and NAD(+) within the catalytic pocket of UXS1, regenerating the essential cofactor NAD(+)., [UniProtKB, UniProtKB, UniProtKB]",
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        "secondary_ac_list": "A0AC58JQE2;A0AC58JQF2",
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        "go_molecular_function": "GO:0008460 dTDP-glucose 4,6-dehydratase activity",
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        "kg_view_protein": true
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    {
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        ],
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        "length": 412,
        "protein_name": "FMR1-interacting protein NUFIP1 isoform X1",
        "gene_name": "nufip1",
        "organism": "Zebrafish",
        "refseq_name": "FMR1-interacting protein NUFIP1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_073808725",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073808725",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "nufip1; fi38f05; wu:fi38f05; zgc:171476",
        "gene_names_refseq": "fi38f05; nufip1; wu:fi38f05; zgc:171476",
        "protein_names_uniprotkb": "FMR1-interacting protein NUFIP1 isoform X1",
        "protein_names_refseq": "FMR1-interacting protein NUFIP1 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "go_biological_process": "",
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        "record_id": "A0AC58JQF6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0AC58JQN4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AC58JQN4",
                "type": "external"
            }
        ],
        "mass": 168433.0,
        "length": 1464,
        "protein_name": "Gypsy retrotransposon integrase-like protein 1",
        "gene_name": "ahcy",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": [],
        "gene_names_uniprotkb": "ahcy; D150; cb1079; ducttrip; hm:zeh1173; hm:zeh1364; wu:fj67b02",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Gypsy retrotransposon integrase-like protein 1; 2.7.7.49; 3.1.26.4",
        "protein_names_refseq": "",
        "tax_id": 7955,
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        "function": "The aspartyl protease (PR) mediates the proteolytic cleavages of the Gag and Gag-Pol polyproteins after assembly of the VLP., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0005525 GTP binding",
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    },
    {
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            {
                "id": "A0ACD6B5Z1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B5Z1",
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        ],
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        "length": 2607,
        "protein_name": "Ankyrin repeat and KH domain-containing protein 1 isoform X1",
        "gene_name": "ankhd1",
        "organism": "Zebrafish",
        "refseq_name": "ankyrin repeat and KH domain-containing protein 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009293757",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009293757",
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        ],
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        "protein_names_refseq": "ankyrin repeat and KH domain-containing protein 1 isoform X1",
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        "disease": "",
        "pathway": " (dre:563327)",
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        "publication_id_list": "19064678;24002024;25355883;26469318;29456083",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009293757.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 6,
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            {
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                "url": "https://www.uniprot.org/uniprot/A0ACD6B7N1",
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        ],
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        "length": 1190,
        "protein_name": "Tubulin--tyrosine ligase-like protein 5",
        "gene_name": "ttll5",
        "organism": "Zebrafish",
        "refseq_name": "tubulin polyglutamylase TTLL5 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_017207366",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207366",
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        ],
        "gene_names_uniprotkb": "ttll5",
        "gene_names_refseq": "ttll5",
        "protein_names_uniprotkb": "Tubulin--tyrosine ligase-like protein 5",
        "protein_names_refseq": "tubulin polyglutamylase TTLL5 isoform X1",
        "tax_id": 7955,
        "disease": "cone-rod dystrophy 19 (Disease Ontology:DOID:0111025)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017207366.2. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 2,
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                "id": "6.3.2.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.2.-",
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        ],
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    {
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        ],
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        "length": 1520,
        "protein_name": "WD repeat-containing protein 62 isoform X1",
        "gene_name": "wdr62",
        "organism": "Zebrafish",
        "refseq_name": "WD repeat-containing protein 62 isoform 2",
        "refseq_ac": [
            {
                "id": "NP_001429277",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429277",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "wdr62; fb33e12; si:ch211-152c12.2; wu:fa11h05; wu:fb33e12",
        "gene_names_refseq": "fb33e12; si:ch211-152c12.2; wdr62; wu:fa11h05; wu:fb33e12",
        "protein_names_uniprotkb": "WD repeat-containing protein 62 isoform X1",
        "protein_names_refseq": "WD repeat-containing protein 62 isoform 2",
        "tax_id": 7955,
        "disease": "primary autosomal recessive microcephaly 2 with or without cortical malformations (Disease Ontology:DOID:0070293); autosomal recessive primary microcephaly (Disease Ontology:DOID:0070296); polymicrogyria (Disease Ontology:DOID:0080918); intellectual disability (Disease Ontology:DOID:1059); microcephaly (Disease Ontology:DOID:10907)",
        "pathway": " (dre:570949)",
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        "publication_count": 10,
        "publication_id_list": "15520368;24153002;26469318;27189481;28252024;31696992;33159854;35808830;36143477;37867960",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395039.519928.1, SRR26395013.520930.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Aug 1, 2025 this sequence version replaced XP_699579.4. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
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        "predicted_o_glycosites": 2,
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        "go_biological_process": "GO:0007507 heart development",
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    {
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        "uniprot_id": [
            {
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                "url": "https://www.uniprot.org/uniprot/A0ACD6B7C5",
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        ],
        "mass": 92300.0,
        "length": 806,
        "protein_name": "Ras GTPase-activating protein 4 isoform X1",
        "gene_name": "rasa4",
        "organism": "Zebrafish",
        "refseq_name": "ras GTPase-activating protein 4 isoform X1",
        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005172052",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "rasa4; si:dkey-93f15.3",
        "gene_names_refseq": "rasa4; si:dkey-93f15.3",
        "protein_names_uniprotkb": "Ras GTPase-activating protein 4 isoform X1",
        "protein_names_refseq": "ras GTPase-activating protein 4 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:567599)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005172052.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005543 phospholipid binding;GO:0008270 zinc ion binding",
        "go_cellular_component": "",
        "go_biological_process": "GO:0046580 negative regulation of Ras protein signal transduction;GO:0035556 intracellular signal transduction;GO:0071277 cellular response to calcium ion",
        "synthesized_glycan_count": 0,
        "hit_score": 0.5,
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        "record_type": "protein",
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        "kg_view_protein": true
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    {
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        "uniprot_id": [
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                "url": "https://www.uniprot.org/uniprot/A0ACD6B7P6",
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        ],
        "mass": 107874.0,
        "length": 976,
        "protein_name": "Echinoderm microtubule-associated protein-like 3 isoform X1",
        "gene_name": "eml3",
        "organism": "Zebrafish",
        "refseq_name": "echinoderm microtubule-associated protein-like 3 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005172258",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005172258",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "eml3",
        "gene_names_refseq": "eml3",
        "protein_names_uniprotkb": "Echinoderm microtubule-associated protein-like 3 isoform X1",
        "protein_names_refseq": "echinoderm microtubule-associated protein-like 3 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005172258.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005874 microtubule;GO:0030496 midbody;GO:0072686 mitotic spindle",
        "go_biological_process": "GO:0051301 cell division",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0ACD6B7P6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0ACD6B7K1-1",
        "uniprot_id": [
            {
                "id": "A0ACD6B7K1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B7K1",
                "type": "external"
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        ],
        "mass": 35847.0,
        "length": 312,
        "protein_name": "Olfactory receptor",
        "gene_name": "or63a2",
        "organism": "Zebrafish",
        "refseq_name": "olfactory receptor 4B13-like",
        "refseq_ac": [
            {
                "id": "XP_001920470",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001920470",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "or63a2; or121-1; or15.5; or63h1",
        "gene_names_refseq": "or63h1",
        "protein_names_uniprotkb": "Olfactory receptor",
        "protein_names_refseq": "olfactory receptor 4B13-like",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100150955)",
        "pathway_count": 1,
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        "publication_id_list": "15824306;16332259;20333175;32295537",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001920470.3. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
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                "id": "A0ACD6B5J6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B5J6",
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        ],
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        "length": 1494,
        "protein_name": "Homeobox protein cut-like",
        "gene_name": "cux1a",
        "organism": "Zebrafish",
        "refseq_name": "homeobox protein cut-like 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005172775",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005172775",
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        ],
        "gene_names_uniprotkb": "cux1a",
        "gene_names_refseq": "cux1a",
        "protein_names_uniprotkb": "Homeobox protein cut-like",
        "protein_names_refseq": "homeobox protein cut-like 1 isoform X1",
        "tax_id": 7955,
        "disease": "stomach cancer (Disease Ontology:DOID:10534); insulinoma (Disease Ontology:DOID:3892); lung non-small cell carcinoma (Disease Ontology:DOID:3908); hepatocellular carcinoma (Disease Ontology:DOID:684)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005172775.1. COMPLETENESS: full length., [RefSeq]",
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        ],
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        "protein_name": "Sodium/mannose cotransporter SLC5A10",
        "gene_name": "slc5a10",
        "organism": "Zebrafish",
        "refseq_name": "sodium/mannose cotransporter SLC5A10 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_017211446",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211446",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "slc5a10",
        "gene_names_refseq": "slc5a10",
        "protein_names_uniprotkb": "Sodium/mannose cotransporter SLC5A10; Sodium/glucose cotransporter 5; Solute carrier family 5 member 10",
        "protein_names_refseq": "sodium/mannose cotransporter SLC5A10 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017211446.2. COMPLETENESS: full length., [RefSeq]; Electrogenic Na+-coupled sugar symporter that actively transports D-mannose or D-fructose at the plasma membrane, with a Na+ to sugar coupling ratio of 1:1. Transporter activity is driven by a transmembrane Na+ electrochemical gradient set by the Na+/K+ pump. Exclusively recognizes sugar substrates having a pyranose ring with an axial hydroxyl group on carbon 2. Has likely evolved to enable renal reabsorption of D-mannose, an important constituent of oligosaccharide chains of glycoproteins. Contributes to dietary D-fructose reabsorption from glomerular filtrate across the brush border of the kidney., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009305960",
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        "gene_names_refseq": "cenpu",
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        "protein_names_refseq": "centromere protein U isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009305960.1. COMPLETENESS: full length., [RefSeq]",
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        "gene_name": "nectin4a",
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            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689011",
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        "gene_names_uniprotkb": "nectin4a",
        "gene_names_refseq": "nectin4a",
        "protein_names_uniprotkb": "Nectin-4 isoform X1",
        "protein_names_refseq": "nectin-4 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_689011.4. COMPLETENESS: full length., [RefSeq]",
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0050501 hyaluronan synthase activity",
        "go_cellular_component": "GO:0016020 membrane",
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        ],
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        "gene_name": "aadac",
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            {
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            {
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        "gene_names_refseq": "asb5a; si:dkeyp-115g4.2; zgc:112531",
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        "protein_names_refseq": "uncharacterized protein LOC550441",
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        ],
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        "gene_names_uniprotkb": "osbpl10b",
        "gene_names_refseq": "osbpl10b",
        "protein_names_uniprotkb": "Oxysterol-binding protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005158298.1. COMPLETENESS: full length., [RefSeq]",
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        ],
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167991",
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            }
        ],
        "gene_names_uniprotkb": "rbm27",
        "gene_names_refseq": "rbm27",
        "protein_names_uniprotkb": "RNA-binding protein 27 isoform X1",
        "protein_names_refseq": "RNA-binding protein 27 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005167991.1. COMPLETENESS: full length., [RefSeq]; May be involved in the turnover of nuclear polyadenylated (pA+) RNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "ec_number_list": [],
        "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding",
        "go_cellular_component": "",
        "go_biological_process": "",
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    {
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            {
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        ],
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        "protein_name": "deoxyribonuclease II",
        "gene_name": "dnase2b",
        "organism": "Zebrafish",
        "refseq_name": "deoxyribonuclease-2-beta isoform X1",
        "refseq_ac": [
            {
                "id": "XP_691451",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691451",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "dnase2b",
        "gene_names_refseq": "dnase2b",
        "protein_names_uniprotkb": "deoxyribonuclease II; 3.1.22.1",
        "protein_names_refseq": "deoxyribonuclease-2-beta isoform X1",
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        "disease": "cataract (Disease Ontology:DOID:83)",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17",
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                "type": "external"
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                "id": "2.7.12.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2",
                "type": "external"
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24",
                "type": "external"
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            {
                "id": "2.7.10.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2",
                "type": "external"
            },
            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23",
                "type": "external"
            },
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                "id": "2.7.1.150",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150",
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12",
                "type": "external"
            },
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39",
                "type": "external"
            },
            {
                "id": "2.7.11.11",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11",
                "type": "external"
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005172945.2. COMPLETENESS: full length., [RefSeq]",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "YEATS domain-containing protein 2",
        "gene_name": "yeats2",
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            {
                "id": "XP_073785406",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors., [UniProtKB, UniProtKB, UniProtKB]",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021323088.1. COMPLETENESS: full length., [RefSeq]",
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            {
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        "protein_names_uniprotkb": "Plasma protease C1 inhibitor isoform X1",
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        "disease": "familial encephalopathy with neuroserpin inclusion bodies (Disease Ontology:DOID:0050831); COVID-19 (Disease Ontology:DOID:0080600); hereditary angioedema type I (Disease Ontology:DOID:0080939); toxic shock syndrome (Disease Ontology:DOID:14115); hereditary angioedema (Disease Ontology:DOID:14735); angioedema (Disease Ontology:DOID:1558); glioblastoma (Disease Ontology:DOID:3068); cerebral infarction (Disease Ontology:DOID:3526); macular degeneration (Disease Ontology:DOID:4448); pancreatitis (Disease Ontology:DOID:4989); autosomal dominant polycystic kidney disease (Disease Ontology:DOID:898); acute myocardial infarction (Disease Ontology:DOID:9408)",
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        "protein_name": "Zinc finger protein 710",
        "gene_name": "znf366",
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            {
                "id": "XP_698186",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698186",
                "type": "external"
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        "gene_names_uniprotkb": "znf366",
        "gene_names_refseq": "znf366",
        "protein_names_uniprotkb": "Zinc finger protein 710",
        "protein_names_refseq": "zinc finger protein 366 isoform X1",
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        "protein_name": "Uncharacterized protein crocc2 isoform X1",
        "gene_name": "crocc2",
        "organism": "Zebrafish",
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        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009300702",
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        "gene_names_refseq": "crocc2",
        "protein_names_uniprotkb": "Uncharacterized protein crocc2 isoform X1",
        "protein_names_refseq": "uncharacterized protein crocc2 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009300702.1. COMPLETENESS: full length., [RefSeq]",
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        "kg_view_protein": true
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            {
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                "url": "https://www.uniprot.org/uniprot/A0ACD6B6F9",
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        ],
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        "length": 476,
        "protein_name": "CD4-1 molecule isoform X1",
        "gene_name": "cd4-1",
        "organism": "Zebrafish",
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            {
                "id": "XP_005173553",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173553",
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            }
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        "gene_names_uniprotkb": "cd4-1; CD4-3; CD4L-1; cd4-4; cd4",
        "gene_names_refseq": "CD4-3; CD4L-1; cd4-1; cd4-4; cd4",
        "protein_names_uniprotkb": "CD4-1 molecule isoform X1",
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        "disease": "COVID-19 (Disease Ontology:DOID:0080600); immunodeficiency 79 (Disease Ontology:DOID:0112277); sialadenitis (Disease Ontology:DOID:10303); severe acute respiratory syndrome (Disease Ontology:DOID:2945); acquired immunodeficiency syndrome (Disease Ontology:DOID:635); amphetamine abuse (Disease Ontology:DOID:670); septic arthritis (Disease Ontology:DOID:813)",
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    {
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        ],
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        "length": 280,
        "protein_name": "Uncharacterized protein",
        "gene_name": "tppp",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001923157",
                "type": "external"
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        ],
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        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001923157.1. COMPLETENESS: full length., [RefSeq]",
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        ],
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        "gene_name": "p3h3",
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            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696266",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "p3h3",
        "gene_names_refseq": "p3h3",
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        "protein_names_refseq": "prolyl 3-hydroxylase 3 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_696266.3. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        ],
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        "protein_name": "Uncharacterized protein si:dkey-260g12.1 isoform X1",
        "gene_name": "si:dkey-260g12.1",
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        "refseq_name": "uncharacterized protein si:dkey-260g12.1 isoform X1",
        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664887",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "si:dkey-260g12.1",
        "gene_names_refseq": "si:dkey-260g12.1",
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        "protein_names_refseq": "uncharacterized protein si:dkey-260g12.1 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_002664887.2. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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    {
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            {
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        ],
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        "protein_name": "Thyrotropin-releasing hormone receptor",
        "gene_name": "trhra",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687246",
                "type": "external"
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        "gene_names_uniprotkb": "trhra",
        "gene_names_refseq": "trhra",
        "protein_names_uniprotkb": "Thyrotropin-releasing hormone receptor; Thyroliberin receptor",
        "protein_names_refseq": "thyrotropin-releasing hormone receptor isoform X1",
        "tax_id": 7955,
        "disease": "congenital hypothyroidism (Disease Ontology:DOID:0050328); congenital nongoitrous hypothyroidism 7 (Disease Ontology:DOID:0111836); hypertension (Disease Ontology:DOID:10763)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_687246.4. COMPLETENESS: full length., [RefSeq]; Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway., [UniProtKB, UniProtKB, UniProtKB]",
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                "url": "https://www.uniprot.org/uniprot/A0ACD6B659",
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        ],
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        "length": 343,
        "protein_name": "NADP-dependent oxidoreductase domain-containing protein 1",
        "gene_name": "noxred1",
        "organism": "Zebrafish",
        "refseq_name": "NADP-dependent oxidoreductase domain-containing protein 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005169929",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169929",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "noxred1",
        "gene_names_refseq": "noxred1",
        "protein_names_uniprotkb": "NADP-dependent oxidoreductase domain-containing protein 1",
        "protein_names_refseq": "NADP-dependent oxidoreductase domain-containing protein 1 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005169929.1. COMPLETENESS: full length., [RefSeq]; Probable oxidoreductase., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "protein_name": "Xaa-Pro aminopeptidase 1",
        "gene_name": "xpnpep1",
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        "gene_names_refseq": "fa02e02; wu:fa02e02; xpnpep1; zgc:56366; zgc:77772",
        "protein_names_uniprotkb": "Xaa-Pro aminopeptidase 1; 3.4.11.9; Aminoacylproline aminopeptidase; Cytosolic aminopeptidase P; Soluble aminopeptidase P; X-Pro aminopeptidase 1; X-prolyl aminopeptidase 1, soluble",
        "protein_names_refseq": "xaa-Pro aminopeptidase 1 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021324983.1. COMPLETENESS: full length., [RefSeq]; Metalloaminopeptidase that catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. Contributes to the degradation of bradykinin., [UniProtKB, UniProtKB]",
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        ],
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687373",
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        "gene_names_uniprotkb": "gdap1l1",
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        "protein_names_uniprotkb": "Ganglioside-induced differentiation-associated protein 1",
        "protein_names_refseq": "ganglioside-induced differentiation-associated protein 1-like 1 isoform X1",
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        "refseq_name": "transmembrane and coiled-coil domain-containing protein 4 isoform X1",
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        ],
        "gene_names_uniprotkb": "tmco4",
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        "protein_names_uniprotkb": "Transmembrane and coiled-coil domain-containing protein 4 isoform X1",
        "protein_names_refseq": "transmembrane and coiled-coil domain-containing protein 4 isoform X1",
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        ],
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        ],
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        "protein_name": "Zinc-binding protein A33 isoform X1",
        "gene_name": "trim35-3",
        "organism": "Zebrafish",
        "refseq_name": "zinc-binding protein A33 isoform X1",
        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009297349",
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            }
        ],
        "gene_names_uniprotkb": "trim35-3",
        "gene_names_refseq": "trim35-3",
        "protein_names_uniprotkb": "Zinc-binding protein A33 isoform X1",
        "protein_names_refseq": "zinc-binding protein A33 isoform X1",
        "tax_id": 7955,
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        "length": 378,
        "protein_name": "Protein FAM117A isoform X1",
        "gene_name": "fam117aa",
        "organism": "Zebrafish",
        "refseq_name": "protein FAM117A isoform X1",
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            {
                "id": "XP_001922260",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922260",
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        "gene_names_uniprotkb": "fam117aa",
        "gene_names_refseq": "fam117aa",
        "protein_names_uniprotkb": "Protein FAM117A isoform X1",
        "protein_names_refseq": "protein FAM117A isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001922260.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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    {
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                "url": "https://www.uniprot.org/uniprot/A0ACD6B5D9",
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        ],
        "mass": 38919.0,
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        "protein_name": "Ubl carboxyl-terminal hydrolase 18 isoform X1",
        "gene_name": "usp18",
        "organism": "Zebrafish",
        "refseq_name": "ubl carboxyl-terminal hydrolase 18 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005164589",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005164589",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "usp18",
        "gene_names_refseq": "usp18",
        "protein_names_uniprotkb": "Ubl carboxyl-terminal hydrolase 18 isoform X1",
        "protein_names_refseq": "ubl carboxyl-terminal hydrolase 18 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005164589.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0016787 hydrolase activity",
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    {
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        ],
        "mass": 44255.0,
        "length": 403,
        "protein_name": "Methylmalonic aciduria type A protein, mitochondrial isoform X1",
        "gene_name": "mmaa",
        "organism": "Zebrafish",
        "refseq_name": "methylmalonic aciduria type A protein, mitochondrial isoform X1",
        "refseq_ac": [
            {
                "id": "XP_017210786",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210786",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "mmaa; zgc:171657",
        "gene_names_refseq": "mmaa; zgc:171657",
        "protein_names_uniprotkb": "Methylmalonic aciduria type A protein, mitochondrial isoform X1",
        "protein_names_refseq": "methylmalonic aciduria type A protein, mitochondrial isoform X1",
        "tax_id": 7955,
        "disease": "methylmalonic acidemia cblA type (Disease Ontology:DOID:0060742); methylmalonic acidemia (Disease Ontology:DOID:14749)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017210786.1. COMPLETENESS: full length., [RefSeq]; GTPase, binds and hydrolyzes GTP. Involved in intracellular vitamin B12 metabolism, mediates the transport of cobalamin (Cbl) into mitochondria for the final steps of adenosylcobalamin (AdoCbl) synthesis. Functions as a G-protein chaperone that assists AdoCbl cofactor delivery from MMAB to the methylmalonyl-CoA mutase (MMUT). Plays a dual role as both a protectase and a reactivase for MMUT. Protects MMUT from progressive inactivation by oxidation by decreasing the rate of the formation of the oxidized inactive cofactor hydroxocobalamin (OH2Cbl). Additionally acts a reactivase by promoting the replacement of OH2Cbl by the active cofactor AdoCbl, restoring the activity of MMUT in the presence and hydrolysis of GTP., [UniProtKB, UniProtKB]",
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        "ec_number_list": [
            {
                "id": "3.6.5.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2",
                "type": "external"
            },
            {
                "id": "3.6.5.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3",
                "type": "external"
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            {
                "id": "3.6.5.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5",
                "type": "external"
            },
            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5",
                "type": "external"
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            {
                "id": "3.6.5.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-",
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            {
                "id": "3.6.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-",
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4",
                "type": "external"
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        ],
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        "kg_view_protein": true
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    {
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        ],
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        "protein_name": "SMC5-SMC6 complex localization factor protein 1 isoform X1",
        "gene_name": "slf1",
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        "refseq_name": "SMC5-SMC6 complex localization factor protein 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005165597",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165597",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "slf1",
        "gene_names_refseq": "slf1",
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        "protein_names_refseq": "SMC5-SMC6 complex localization factor protein 1 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005165597.2. COMPLETENESS: full length., [RefSeq]",
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    {
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            {
                "id": "A0ACD6B7S0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B7S0",
                "type": "external"
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        ],
        "mass": 59827.0,
        "length": 518,
        "protein_name": "Phosphodiesterase",
        "gene_name": "pde9ab",
        "organism": "Zebrafish",
        "refseq_name": "high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1",
        "refseq_ac": [
            {
                "id": "XP_700447",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_700447",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pde9ab",
        "gene_names_refseq": "pde9ab",
        "protein_names_uniprotkb": "Phosphodiesterase; 3.1.4.-",
        "protein_names_refseq": "high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1",
        "tax_id": 7955,
        "disease": "dilated cardiomyopathy (Disease Ontology:DOID:12930); congestive heart failure (Disease Ontology:DOID:6000)",
        "pathway": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_700447.5. COMPLETENESS: full length., [RefSeq]; Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP. Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart. Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein. In brain, involved in cognitive function, such as learning and long-term memory., [UniProtKB, UniProtKB, UniProtKB]",
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                "url": "https://www.uniprot.org/uniprot/A0ACD6B6C0",
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            }
        ],
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        "length": 564,
        "protein_name": "Tetratricopeptide repeat protein 22 isoform X1",
        "gene_name": "ttc22",
        "organism": "Zebrafish",
        "refseq_name": "tetratricopeptide repeat protein 22 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_021327451",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327451",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ttc22",
        "gene_names_refseq": "ttc22",
        "protein_names_uniprotkb": "Tetratricopeptide repeat protein 22 isoform X1",
        "protein_names_refseq": "tetratricopeptide repeat protein 22 isoform X1",
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        "kg_view_protein": true
    },
    {
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            {
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        ],
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        "gene_name": "eevs",
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        "refseq_name": "2-epi-5-epi-valiolone synthase isoform X1",
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            {
                "id": "XP_001343422",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001343422",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "eevs",
        "gene_names_refseq": "eevs",
        "protein_names_uniprotkb": "2-epi-5-epi-valiolone synthase isoform X1",
        "protein_names_refseq": "2-epi-5-epi-valiolone synthase isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001343422.1. COMPLETENESS: full length., [RefSeq]",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AC58JWD7-1",
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            {
                "id": "A0AC58JWD7_DANRE",
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        ],
        "mass": 159365.0,
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        "protein_name": "Kinesin-like protein KIF16B",
        "gene_name": "kif16ba",
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        "refseq_ac": [
            {
                "id": "XP_073810801",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073810801",
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            }
        ],
        "gene_names_uniprotkb": "kif16ba",
        "gene_names_refseq": "kif16ba",
        "protein_names_uniprotkb": "Kinesin-like protein KIF16B",
        "protein_names_refseq": "kinesin-like protein KIF16B isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plus end-directed microtubule-dependent motor protein involved in endosome transport and receptor recycling and degradation. Regulates the plus end motility of early endosomes and the balance between recycling and degradation of receptors such as EGF receptor (EGFR) and FGF receptor (FGFR). Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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                "id": "A0AC58JWE8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AC58JWE8",
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        ],
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        "protein_name": "Cadherin-22",
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        "organism": "Zebrafish",
        "refseq_name": "cadherin 22 isoform 1 precursor",
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                "id": "NP_001430379",
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        "protein_names_uniprotkb": "Cadherin-22; Pituitary and brain cadherin",
        "protein_names_refseq": "cadherin 22 isoform 1 precursor; zmp:0000001153",
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            {
                "id": "XP_002662849",
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        "disease": "adult T-cell leukemia/lymphoma (Disease Ontology:DOID:0050523); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); endometriosis of pelvic peritoneum (Disease Ontology:DOID:11429); primary biliary cholangitis (Disease Ontology:DOID:12236); diverticulitis of colon (Disease Ontology:DOID:13254); hepatitis B (Disease Ontology:DOID:2043); Epstein-Barr virus infectious disease (Disease Ontology:DOID:2938); severe acute respiratory syndrome (Disease Ontology:DOID:2945); Merkel cell carcinoma (Disease Ontology:DOID:3965); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); acquired immunodeficiency syndrome (Disease Ontology:DOID:635); hepatocellular carcinoma (Disease Ontology:DOID:684); Hodgkin's lymphoma (Disease Ontology:DOID:8567)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021336824.1. COMPLETENESS: full length., [RefSeq]",
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        "protein_names_refseq": "complement C1q tumor necrosis factor-related protein 7",
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        "protein_name": "Odorant receptor 131-2-like",
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        ],
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        "protein_name": "Aryl-hydrocarbon-interacting protein-like 1",
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        "organism": "Zebrafish",
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                "type": "external"
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        "gene_names_uniprotkb": "aipl1",
        "gene_names_refseq": "aipl1",
        "protein_names_uniprotkb": "Aryl-hydrocarbon-interacting protein-like 1",
        "protein_names_refseq": "aryl-hydrocarbon-interacting protein-like 1",
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        "disease": "Leber congenital amaurosis 4 (Disease Ontology:DOID:0110332); retinitis pigmentosa (Disease Ontology:DOID:10584); blindness (Disease Ontology:DOID:1432); Leber congenital amaurosis (Disease Ontology:DOID:14791)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322106.1. COMPLETENESS: full length., [RefSeq]; May be important in protein trafficking and/or protein folding and stabilization., [UniProtKB, UniProtKB]",
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        "kg_view_protein": true
    },
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            {
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                "url": "https://www.uniprot.org/uniprot/A0ACD6B5L3",
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        ],
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        "protein_name": "snRNA-activating protein complex subunit 2",
        "gene_name": "snapc2",
        "organism": "Zebrafish",
        "refseq_name": "snRNA-activating protein complex subunit 2",
        "refseq_ac": [
            {
                "id": "XP_001923727",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001923727",
                "type": "external"
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        "gene_names_uniprotkb": "snapc2",
        "gene_names_refseq": "snapc2",
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        "protein_names_refseq": "snRNA-activating protein complex subunit 2",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001923727.1. COMPLETENESS: full length., [RefSeq]",
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        ],
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        "length": 505,
        "protein_name": "Nectin cell adhesion molecule 3",
        "gene_name": "si:ch73-22o12.1",
        "organism": "Zebrafish",
        "refseq_name": "poliovirus receptor",
        "refseq_ac": [
            {
                "id": "XP_021322530",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322530",
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        "gene_names_uniprotkb": "si:ch73-22o12.1",
        "gene_names_refseq": "si:ch73-22o12.1",
        "protein_names_uniprotkb": "Nectin cell adhesion molecule 3",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322530.1. COMPLETENESS: full length., [RefSeq]; Cell adhesion molecule that promotes cell-cell contacts and plays important roles in the development of the nervous system. Acts by forming homophilic or heterophilic trans-dimers., [UniProtKB, UniProtKB]",
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    {
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        "protein_name": "Attractin-like protein 1",
        "gene_name": "atrnl1b",
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                "id": "XP_697655",
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                "type": "external"
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        ],
        "gene_names_uniprotkb": "atrnl1b",
        "gene_names_refseq": "atrnl1b",
        "protein_names_uniprotkb": "Attractin-like protein 1",
        "protein_names_refseq": "attractin-like protein 1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_697655.4. COMPLETENESS: full length., [RefSeq]",
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        ],
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        "protein_name": "Coiled-coil domain-containing 92B",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009296259.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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                "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.16",
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.3.2",
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            },
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            {
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                "type": "external"
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.2",
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        ],
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        "protein_name": "Vesicle transport protein GOT1A",
        "gene_name": "golt1a",
        "organism": "Zebrafish",
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        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001336385",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "golt1a",
        "gene_names_refseq": "golt1a",
        "protein_names_uniprotkb": "Vesicle transport protein GOT1A",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001336385.1. COMPLETENESS: full length., [RefSeq]; May be involved in fusion of ER-derived transport vesicles with the Golgi complex., [UniProtKB, UniProtKB]",
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        "protein_name": "Tumor necrosis factor receptor superfamily member 18 isoform X1",
        "gene_name": "tnfrsf18",
        "organism": "Zebrafish",
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        "protein_names_uniprotkb": "Tumor necrosis factor receptor superfamily member 18 isoform X1",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.4",
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            },
            {
                "id": "3.1.3.106",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.106",
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.75",
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            },
            {
                "id": "3.6.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-",
                "type": "external"
            },
            {
                "id": "3.1.3.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-",
                "type": "external"
            },
            {
                "id": "3.6.1.68",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.68",
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    {
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        ],
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        "length": 684,
        "protein_name": "Pleckstrin homology domain-containing family O member 2",
        "gene_name": "plekho2",
        "organism": "Zebrafish",
        "refseq_name": "pleckstrin homology domain-containing family O member 2",
        "refseq_ac": [
            {
                "id": "XP_002662798",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002662798",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "plekho2",
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        "protein_names_uniprotkb": "Pleckstrin homology domain-containing family O member 2",
        "protein_names_refseq": "pleckstrin homology domain-containing family O member 2",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_002662798.2. COMPLETENESS: full length., [RefSeq]",
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        ],
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        "length": 148,
        "protein_name": "Protein FAM107B",
        "gene_name": "si:ch211-160o17.6",
        "organism": "Zebrafish",
        "refseq_name": "protein FAM107B",
        "refseq_ac": [
            {
                "id": "XP_001922304",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922304",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "si:ch211-160o17.6",
        "gene_names_refseq": "si:ch211-160o17.6",
        "protein_names_uniprotkb": "Protein FAM107B",
        "protein_names_refseq": "protein FAM107B",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001922304.2. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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    {
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        ],
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        "length": 347,
        "protein_name": "Sodium/potassium-transporting ATPase subunit beta",
        "gene_name": "atp1b4",
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        "refseq_name": "protein ATP1B4 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_002664470",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664470",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "atp1b4",
        "gene_names_refseq": "atp1b4",
        "protein_names_uniprotkb": "Sodium/potassium-transporting ATPase subunit beta",
        "protein_names_refseq": "protein ATP1B4 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_002664470.2. COMPLETENESS: full length., [RefSeq]; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "protein_name": "Rho GTPase-activating protein SYDE1",
        "gene_name": "syde1",
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        "refseq_name": "rho GTPase-activating protein SYDE1",
        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696571",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "syde1",
        "gene_names_refseq": "syde1",
        "protein_names_uniprotkb": "Rho GTPase-activating protein SYDE1; Synapse defective protein 1 homolog 1",
        "protein_names_refseq": "rho GTPase-activating protein SYDE1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_696571.6. COMPLETENESS: full length., [RefSeq]; GTPase activator for the Rho-type GTPases. As a GCM1 downstream effector, it is involved in placental development and positively regulates trophoblast cells migration. It regulates cytoskeletal remodeling by controlling the activity of Rho GTPases including RHOA, CDC42 and RAC1., [UniProtKB, UniProtKB]",
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        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "zgc:92380",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303246",
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        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009303246.1. COMPLETENESS: full length., [RefSeq]",
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        "hit_score": 0.1,
        "record_id": "A0ACD6B5P9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0ACD6B5Q5-1",
        "uniprot_id": [
            {
                "id": "A0ACD6B5Q5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B5Q5",
                "type": "external"
            }
        ],
        "mass": 30692.0,
        "length": 254,
        "protein_name": "Uncharacterized protein si:ch73-193c12.2",
        "gene_name": "si:ch73-193c12.2",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch73-193c12.2",
        "refseq_ac": [
            {
                "id": "XP_001344933",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001344933",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch73-193c12.2",
        "gene_names_refseq": "si:ch73-193c12.2",
        "protein_names_uniprotkb": "Uncharacterized protein si:ch73-193c12.2",
        "protein_names_refseq": "uncharacterized protein si:ch73-193c12.2",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001344933.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0ACD6B5Q5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0ACD6B5Q8-1",
        "uniprot_id": [
            {
                "id": "A0ACD6B5Q8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B5Q8",
                "type": "external"
            }
        ],
        "mass": 17200.0,
        "length": 153,
        "protein_name": "Sulfiredoxin-1",
        "gene_name": "srxn1",
        "organism": "Zebrafish",
        "refseq_name": "sulfiredoxin-1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_002663173",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002663173",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "srxn1",
        "gene_names_refseq": "srxn1",
        "protein_names_uniprotkb": "Sulfiredoxin-1; 1.8.98.2",
        "protein_names_refseq": "sulfiredoxin-1 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_002663173.1. COMPLETENESS: full length., [RefSeq]; Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
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        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "1.8.98.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.98.2",
                "type": "external"
            }
        ],
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0ACD6B5Q8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0ACD6B5R3-1",
        "uniprot_id": [
            {
                "id": "A0ACD6B5R3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B5R3",
                "type": "external"
            }
        ],
        "mass": 39860.0,
        "length": 351,
        "protein_name": "Chemokine XC receptor 1",
        "gene_name": "xcr1b.2",
        "organism": "Zebrafish",
        "refseq_name": "chemokine XC receptor 1",
        "refseq_ac": [
            {
                "id": "XP_005171500",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171500",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "xcr1b.2",
        "gene_names_refseq": "xcr1b.2",
        "protein_names_uniprotkb": "Chemokine XC receptor 1",
        "protein_names_refseq": "chemokine XC receptor 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005171500.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0ACD6B5R3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0ACD6B5R7-1",
        "uniprot_id": [
            {
                "id": "A0ACD6B5R7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B5R7",
                "type": "external"
            }
        ],
        "mass": 62017.0,
        "length": 572,
        "protein_name": "Max-binding protein MNT",
        "gene_name": "mntb",
        "organism": "Zebrafish",
        "refseq_name": "MAX network transcriptional repressor b isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005170328",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170328",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mntb; Mnt; zgc:165490",
        "gene_names_refseq": "Mnt; mntb; zgc:165490",
        "protein_names_uniprotkb": "Max-binding protein MNT; Myc antagonist MNT",
        "protein_names_refseq": "MAX network transcriptional repressor b isoform X1",
        "tax_id": 7955,
        "disease": "Miller-Dieker lissencephaly syndrome (Disease Ontology:DOID:0060469)",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005170328.1. COMPLETENESS: full length., [RefSeq]; Binds DNA as a heterodimer with MAX and represses transcription. Binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 2,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 2,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 1,
        "glyco_site_count": 2,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0ACD6B5R7-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0ACD6B5R8-1",
        "uniprot_id": [
            {
                "id": "A0ACD6B5R8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B5R8",
                "type": "external"
            }
        ],
        "mass": 102206.0,
        "length": 905,
        "protein_name": "Inter-alpha-trypsin inhibitor heavy chain H3",
        "gene_name": "itih3a.2",
        "organism": "Zebrafish",
        "refseq_name": "inter-alpha-trypsin inhibitor heavy chain H3",
        "refseq_ac": [
            {
                "id": "XP_693183",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693183",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "itih3a.2",
        "gene_names_refseq": "itih3a.2",
        "protein_names_uniprotkb": "Inter-alpha-trypsin inhibitor heavy chain H3",
        "protein_names_refseq": "inter-alpha-trypsin inhibitor heavy chain H3",
        "tax_id": 7955,
        "disease": "",
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        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_693183.4. COMPLETENESS: full length., [RefSeq]; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "total_n_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0ACD6B5R8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0ACD6B5R9-1",
        "uniprot_id": [
            {
                "id": "A0ACD6B5R9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B5R9",
                "type": "external"
            }
        ],
        "mass": 83121.0,
        "length": 747,
        "protein_name": "Uncharacterized protein cax2",
        "gene_name": "cax2",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein cax2",
        "refseq_ac": [
            {
                "id": "XP_068073623",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073623",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cax2",
        "gene_names_refseq": "cax2",
        "protein_names_uniprotkb": "Uncharacterized protein cax2",
        "protein_names_refseq": "uncharacterized protein cax2",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068073623.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        ],
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        "protein_names_refseq": "putative transcription factor Ovo-like 1",
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        "gene_names_uniprotkb": "sdhaf1",
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        "protein_names_refseq": "succinate dehydrogenase assembly factor 1, mitochondrial",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_002665987.1. COMPLETENESS: full length., [RefSeq]",
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        ],
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        "length": 253,
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        ],
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        "length": 821,
        "protein_name": "BTB/POZ domain-containing protein KCTD3",
        "gene_name": "kctd3",
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        "refseq_name": "BTB/POZ domain-containing protein KCTD3",
        "refseq_ac": [
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                "type": "external"
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        ],
        "gene_names_uniprotkb": "kctd3",
        "gene_names_refseq": "kctd3",
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        "protein_names_refseq": "BTB/POZ domain-containing protein KCTD3",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_697568.4. COMPLETENESS: full length., [RefSeq]; Accessory subunit of potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (HCN3) up-regulating its cell-surface expression and current density without affecting its voltage dependence and kinetics., [UniProtKB, UniProtKB]",
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        ],
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        "gene_names_uniprotkb": "dipk2ab; c3orf58b; dia1b",
        "gene_names_refseq": "c3orf58b; dia1b; dipk2ab",
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        "protein_names_refseq": "divergent protein kinase domain 2Ab isoform X1",
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        "protein_names_refseq": "prostaglandin F2 receptor negative regulator",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009302671.1. COMPLETENESS: full length., [RefSeq]",
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        "synthesized_glycan_count": 0,
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        "record_id": "A0ACD6B7Q9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0ACD6B694-1",
        "uniprot_id": [
            {
                "id": "A0ACD6B694_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B694",
                "type": "external"
            }
        ],
        "mass": 32256.0,
        "length": 297,
        "protein_name": "Protein phosphatase",
        "gene_name": "pptc7b",
        "organism": "Zebrafish",
        "refseq_name": "protein phosphatase PTC7 homolog",
        "refseq_ac": [
            {
                "id": "XP_009303413",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303413",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pptc7b",
        "gene_names_refseq": "pptc7b",
        "protein_names_uniprotkb": "Protein phosphatase; 3.1.3.16",
        "protein_names_refseq": "protein phosphatase PTC7 homolog",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009303413.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "ec_number_list": [
            {
                "id": "3.1.3.16",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16",
                "type": "external"
            },
            {
                "id": "3.1.3.48",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48",
                "type": "external"
            },
            {
                "id": "3.1.3.67",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67",
                "type": "external"
            },
            {
                "id": "3.1.3.27",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27",
                "type": "external"
            }
        ],
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        "synthesized_glycan_count": 0,
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0ACD6B6A1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B6A1",
                "type": "external"
            }
        ],
        "mass": 36330.0,
        "length": 325,
        "protein_name": "Intelectin-like isoform X1",
        "gene_name": "si:ch211-194p6.4",
        "organism": "Zebrafish",
        "refseq_name": "intelectin-like isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005168969",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168969",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch211-194p6.4; zgc:153219",
        "gene_names_refseq": "si:ch211-194p6.4; zgc:153219",
        "protein_names_uniprotkb": "Intelectin-like isoform X1",
        "protein_names_refseq": "intelectin-like isoform X1",
        "tax_id": 7955,
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        "pathway_count": 0,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005168969.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "go_molecular_function": "",
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0ACD6B6A1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0ACD6B6A7-1",
        "uniprot_id": [
            {
                "id": "A0ACD6B6A7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B6A7",
                "type": "external"
            }
        ],
        "mass": 109130.0,
        "length": 999,
        "protein_name": "Iron-responsive element-binding protein 2",
        "gene_name": "ireb2",
        "organism": "Zebrafish",
        "refseq_name": "iron-responsive element-binding protein 2",
        "refseq_ac": [
            {
                "id": "XP_005163029",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005163029",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ireb2",
        "gene_names_refseq": "ireb2",
        "protein_names_uniprotkb": "Iron-responsive element-binding protein 2",
        "protein_names_refseq": "iron-responsive element-binding protein 2",
        "tax_id": 7955,
        "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083)",
        "pathway": "",
        "pathway_count": 0,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005163029.1. COMPLETENESS: full length., [RefSeq]; RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "predicted_s_glycosites": 0,
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        "reported_n_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "",
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        "synthesized_glycan_count": 0,
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        "record_id": "A0ACD6B6A7-1",
        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0ACD6B6B0-1",
        "uniprot_id": [
            {
                "id": "A0ACD6B6B0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B6B0",
                "type": "external"
            }
        ],
        "mass": 22313.0,
        "length": 194,
        "protein_name": "U3 small nucleolar RNA-associated protein NOL7",
        "gene_name": "nol7",
        "organism": "Zebrafish",
        "refseq_name": "U3 small nucleolar RNA-associated protein NOL7",
        "refseq_ac": [
            {
                "id": "XP_687281",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687281",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "nol7",
        "gene_names_refseq": "nol7",
        "protein_names_uniprotkb": "U3 small nucleolar RNA-associated protein NOL7",
        "protein_names_refseq": "U3 small nucleolar RNA-associated protein NOL7",
        "tax_id": 7955,
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        "pathway_count": 0,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_687281.4. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_n_glycosites": 0,
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        "total_reported_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0ACD6B6B5",
                "type": "external"
            }
        ],
        "mass": 61066.0,
        "length": 546,
        "protein_name": "Solute carrier family 22 member 6",
        "gene_name": "slc22a7b.3",
        "organism": "Zebrafish",
        "refseq_name": "solute carrier family 22 member 7",
        "refseq_ac": [
            {
                "id": "XP_001337264",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001337264",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "slc22a7b.3",
        "gene_names_refseq": "slc22a7b.3",
        "protein_names_uniprotkb": "Solute carrier family 22 member 6; Organic anion transporter 1; Renal organic anion transporter 1",
        "protein_names_refseq": "solute carrier family 22 member 7",
        "tax_id": 7955,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001337264.3. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "predicted_s_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "record_id": "A0ACD6B6B5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0ACD6B6B7-1",
        "uniprot_id": [
            {
                "id": "A0ACD6B6B7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B6B7",
                "type": "external"
            }
        ],
        "mass": 96363.0,
        "length": 861,
        "protein_name": "DNA topoisomerase",
        "gene_name": "top3b",
        "organism": "Zebrafish",
        "refseq_name": "DNA topoisomerase 3-beta-1",
        "refseq_ac": [
            {
                "id": "XP_003198651",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003198651",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "top3b",
        "gene_names_refseq": "top3b",
        "protein_names_uniprotkb": "DNA topoisomerase; 5.6.2.1",
        "protein_names_refseq": "DNA topoisomerase 3-beta-1",
        "tax_id": 7955,
        "disease": "",
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        "pathway_count": 0,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_003198651.1. COMPLETENESS: full length., [RefSeq]; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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            {
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        ],
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        "length": 481,
        "protein_name": "LETM1 domain-containing protein LETM2, mitochondrial",
        "gene_name": "letm2",
        "organism": "Zebrafish",
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        "refseq_ac": [
            {
                "id": "XP_001339387",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001339387",
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        ],
        "gene_names_uniprotkb": "letm2",
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        "protein_names_refseq": "LETM1 domain-containing protein LETM2, mitochondrial",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001339387.1. COMPLETENESS: full length., [RefSeq]",
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        ],
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        "protein_name": "Tyrosine-protein phosphatase non-receptor type 9",
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        "refseq_ac": [
            {
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        "protein_names_refseq": "tyrosine-protein phosphatase non-receptor type 9",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_690659.5. COMPLETENESS: full length., [RefSeq]; Protein-tyrosine phosphatase that could participate in the transfer of hydrophobic ligands or in functions of the Golgi apparatus., [UniProtKB, UniProtKB]",
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        "protein_names_refseq": "cytoplasmic 60S subunit biogenesis factor ZNF622",
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            {
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        ],
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        "protein_name": "Nuclear factor 7, brain isoform X1",
        "gene_name": "trim35-7",
        "organism": "Zebrafish",
        "refseq_name": "nuclear factor 7, brain isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005163760",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005163760",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "trim35-7; si:ch73-106l15.3",
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        "protein_names_refseq": "nuclear factor 7, brain isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005163760.1. COMPLETENESS: full length., [RefSeq]",
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    {
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        ],
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        "length": 1057,
        "protein_name": "Storkhead-box protein 2 isoform X1",
        "gene_name": "stox2a",
        "organism": "Zebrafish",
        "refseq_name": "storkhead-box protein 2 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_001922898",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922898",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "stox2a",
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        "protein_names_uniprotkb": "Storkhead-box protein 2 isoform X1",
        "protein_names_refseq": "storkhead-box protein 2 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001922898.3. COMPLETENESS: full length., [RefSeq]",
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        ],
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        "protein_name": "TBC1 domain family member 15",
        "gene_name": "tbc1d17",
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        "refseq_ac": [
            {
                "id": "NP_001019565",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019565",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tbc1d17; wu:fc56c02; zgc:110443",
        "gene_names_refseq": "tbc1d17; wu:fc56c02; zgc:110443",
        "protein_names_uniprotkb": "TBC1 domain family member 15; GTPase-activating protein RAB7",
        "protein_names_refseq": "TBC1 domain family member 17",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC066727.1, GDQH01005942.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On or before Jul 18, 2025 this sequence version replaced XP_005164004.2, NP_001019565.1., [RefSeq]; Acts as a GTPase activating protein for RAB7A. Does not act on RAB4, RAB5 or RAB6., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "gene_name": "sec22a",
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        ],
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        "gene_names_refseq": "fc44f07; sec22a; sec22l2; wu:fc44f07; zgc:56686",
        "protein_names_uniprotkb": "Vesicle-trafficking protein SEC22a isoform X1",
        "protein_names_refseq": "vesicle-trafficking protein SEC22a isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021334284.1. COMPLETENESS: full length., [RefSeq]; May be involved in vesicle transport between the ER and the Golgi complex., [UniProtKB, UniProtKB]",
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        "protein_name": "Neurotrypsin",
        "gene_name": "si:ch211-51a6.2",
        "organism": "Zebrafish",
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            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690649",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "si:ch211-51a6.2",
        "gene_names_refseq": "si:ch211-51a6.2",
        "protein_names_uniprotkb": "Neurotrypsin; Serine protease 12",
        "protein_names_refseq": "neurotrypsin",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_690649.2. COMPLETENESS: full length., [RefSeq]; Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "kg_view_protein": true
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    {
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        ],
        "mass": 180235.0,
        "length": 1619,
        "protein_name": "Protein turtle homolog B",
        "gene_name": "igsf9a",
        "organism": "Zebrafish",
        "refseq_name": "protein turtle homolog B",
        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155702",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "igsf9a",
        "gene_names_refseq": "igsf9a",
        "protein_names_uniprotkb": "Protein turtle homolog B",
        "protein_names_refseq": "protein turtle homolog B",
        "tax_id": 7955,
        "disease": "depressive disorder (Disease Ontology:DOID:1596)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005155702.1. COMPLETENESS: full length., [RefSeq]",
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        "gene_name": "si:ch1073-416j23.1",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695377",
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        "gene_name": "znf654",
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        "protein_names_refseq": "WAS/WASL-interacting protein family member 2",
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                "id": "A0ACD6B6L5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B6L5",
                "type": "external"
            }
        ],
        "mass": 112333.0,
        "length": 1036,
        "protein_name": "Transcriptional activator MN1",
        "gene_name": "mn1a",
        "organism": "Zebrafish",
        "refseq_name": "transcriptional activator MN1",
        "refseq_ac": [
            {
                "id": "XP_700922",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_700922",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mn1a",
        "gene_names_refseq": "mn1a",
        "protein_names_uniprotkb": "Transcriptional activator MN1",
        "protein_names_refseq": "transcriptional activator MN1",
        "tax_id": 7955,
        "disease": "meningioma (Disease Ontology:DOID:3565); familial meningioma (Disease Ontology:DOID:4586); myeloid leukemia (Disease Ontology:DOID:8692)",
        "pathway": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_700922.5. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "kg_view_protein": true
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    {
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            {
                "id": "A0ACD6B6M3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B6M3",
                "type": "external"
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        ],
        "mass": 56777.0,
        "length": 488,
        "protein_name": "Hexosyltransferase",
        "gene_name": "csgalnact1b",
        "organism": "Zebrafish",
        "refseq_name": "chondroitin sulfate N-acetylgalactosaminyltransferase 1",
        "refseq_ac": [
            {
                "id": "XP_005166733",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166733",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "csgalnact1b",
        "gene_names_refseq": "csgalnact1b",
        "protein_names_uniprotkb": "Hexosyltransferase; 2.4.1.-",
        "protein_names_refseq": "chondroitin sulfate N-acetylgalactosaminyltransferase 1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005166733.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0ACD6B6M6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B6M6",
                "type": "external"
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        ],
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        "length": 265,
        "protein_name": "Uncharacterized protein si:dkeyp-72g9.4",
        "gene_name": "si:dkeyp-72g9.4",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:dkeyp-72g9.4",
        "refseq_ac": [
            {
                "id": "XP_017208442",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208442",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:dkeyp-72g9.4",
        "gene_names_refseq": "si:dkeyp-72g9.4",
        "protein_names_uniprotkb": "Uncharacterized protein si:dkeyp-72g9.4",
        "protein_names_refseq": "uncharacterized protein si:dkeyp-72g9.4",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017208442.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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    },
    {
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                "url": "https://www.uniprot.org/uniprot/A0ACD6B6N8",
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        ],
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        "length": 1256,
        "protein_name": "Cohesin subunit SA",
        "gene_name": "stag1b",
        "organism": "Zebrafish",
        "refseq_name": "cohesin subunit SA-1",
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            {
                "id": "XP_692120",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692120",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "stag1b",
        "gene_names_refseq": "stag1b",
        "protein_names_uniprotkb": "Cohesin subunit SA; SCC3 homolog; Stromal antigen",
        "protein_names_refseq": "cohesin subunit SA-1",
        "tax_id": 7955,
        "disease": "autosomal dominant intellectual developmental disorder 47 (Disease Ontology:DOID:0080238)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_692120.3. COMPLETENESS: full length., [RefSeq]; Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate., [UniProtKB, UniProtKB]",
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    {
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            {
                "id": "A0ACD6B6P1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B6P1",
                "type": "external"
            }
        ],
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        "length": 321,
        "protein_name": "Solute carrier family 25 member 16 isoform X1",
        "gene_name": "slc25a16",
        "organism": "Zebrafish",
        "refseq_name": "solute carrier family 25 member 16 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009305500",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009305500",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "slc25a16; wu:fc33c08; zgc:56187; zgc:77742",
        "gene_names_refseq": "slc25a16; wu:fc33c08; zgc:56187; zgc:77742",
        "protein_names_uniprotkb": "Solute carrier family 25 member 16 isoform X1",
        "protein_names_refseq": "solute carrier family 25 member 16 isoform X1",
        "tax_id": 7955,
        "disease": "Graves' disease (Disease Ontology:DOID:12361)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009305500.1. COMPLETENESS: full length., [RefSeq]",
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    {
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        ],
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        "protein_name": "Fibronectin type 3 and ankyrin repeat domains protein 1 isoform X1",
        "gene_name": "fank1",
        "organism": "Zebrafish",
        "refseq_name": "fibronectin type 3 and ankyrin repeat domains protein 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_002664080",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664080",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "fank1",
        "gene_names_refseq": "fank1",
        "protein_names_uniprotkb": "Fibronectin type 3 and ankyrin repeat domains protein 1 isoform X1",
        "protein_names_refseq": "fibronectin type 3 and ankyrin repeat domains protein 1 isoform X1",
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        "missing_score": 10000,
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        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
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                "url": "https://www.uniprot.org/uniprot/A0ACD6B6P9",
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        ],
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        "protein_name": "Uncharacterized protein akap1a",
        "gene_name": "akap1a",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein akap1a",
        "refseq_ac": [
            {
                "id": "XP_001342303",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001342303",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "akap1a",
        "gene_names_refseq": "akap1a",
        "protein_names_uniprotkb": "Uncharacterized protein akap1a",
        "protein_names_refseq": "uncharacterized protein akap1a",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001342303.3. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "reported_snv": 0,
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        "missing_score": 10000,
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                "url": "https://www.uniprot.org/uniprot/A0ACD6B6Q0",
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        ],
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        "length": 643,
        "protein_name": "Ubiquitin-associated and SH3 domain-containing protein B",
        "gene_name": "ubash3ba",
        "organism": "Zebrafish",
        "refseq_name": "ubiquitin-associated and SH3 domain-containing protein B",
        "refseq_ac": [
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                "id": "XP_001923885",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001923885",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ubash3ba",
        "gene_names_refseq": "ubash3ba",
        "protein_names_uniprotkb": "Ubiquitin-associated and SH3 domain-containing protein B; 3.1.3.48; Cbl-interacting protein p70; Suppressor of T-cell receptor signaling 1; T-cell ubiquitin ligand 2; Tyrosine-protein phosphatase STS1/TULA2",
        "protein_names_refseq": "ubiquitin-associated and SH3 domain-containing protein B",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001923885.2. COMPLETENESS: full length., [RefSeq]; Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "3.1.3.16",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16",
                "type": "external"
            },
            {
                "id": "3.1.3.48",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48",
                "type": "external"
            },
            {
                "id": "3.1.3.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2",
                "type": "external"
            },
            {
                "id": "3.1.3.67",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67",
                "type": "external"
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            {
                "id": "3.1.3.27",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27",
                "type": "external"
            },
            {
                "id": "3.1.3.21",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21",
                "type": "external"
            }
        ],
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        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
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        "kg_view_protein": true
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    {
        "uniprot_canonical_ac": "A0ACD6B6Q1-1",
        "uniprot_id": [
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                "type": "external"
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        ],
        "mass": 38703.0,
        "length": 354,
        "protein_name": "Aspartate beta-hydroxylase domain-containing protein 2",
        "gene_name": "asphd1",
        "organism": "Zebrafish",
        "refseq_name": "aspartate beta-hydroxylase domain-containing protein 2",
        "refseq_ac": [
            {
                "id": "XP_021330567",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330567",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "asphd1",
        "gene_names_refseq": "asphd1",
        "protein_names_uniprotkb": "Aspartate beta-hydroxylase domain-containing protein 2",
        "protein_names_refseq": "aspartate beta-hydroxylase domain-containing protein 2",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021330567.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "go_biological_process": "",
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        "kg_view_protein": true
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    {
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        "uniprot_id": [
            {
                "id": "A0ACD6B6R2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B6R2",
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        ],
        "mass": 41794.0,
        "length": 369,
        "protein_name": "Uncharacterized protein si:dkey-32e6.3",
        "gene_name": "si:dkey-32e6.3",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:dkey-32e6.3",
        "refseq_ac": [
            {
                "id": "XP_001341616",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001341616",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:dkey-32e6.3",
        "gene_names_refseq": "si:dkey-32e6.3",
        "protein_names_uniprotkb": "Uncharacterized protein si:dkey-32e6.3",
        "protein_names_refseq": "uncharacterized protein si:dkey-32e6.3",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001341616.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "kg_view_protein": true
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                "url": "https://www.uniprot.org/uniprot/A0ACD6B6R7",
                "type": "external"
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        ],
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        "length": 739,
        "protein_name": "ATP-dependent RNA helicase",
        "gene_name": "ddx31",
        "organism": "Zebrafish",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332164",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ddx31",
        "gene_names_refseq": "ddx31",
        "protein_names_uniprotkb": "ATP-dependent RNA helicase; 3.6.4.13",
        "protein_names_refseq": "ATP-dependent DNA helicase DDX31",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021332164.1. COMPLETENESS: full length., [RefSeq]; RNA helicase., [UniProtKB, UniProtKB]",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13",
                "type": "external"
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3",
                "type": "external"
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                "id": "7.6.2.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2",
                "type": "external"
            },
            {
                "id": "5.6.1.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6",
                "type": "external"
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            {
                "id": "7.6.2.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3",
                "type": "external"
            },
            {
                "id": "3.6.1.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5",
                "type": "external"
            },
            {
                "id": "3.6.4.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6",
                "type": "external"
            },
            {
                "id": "3.6.1.15",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15",
                "type": "external"
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            {
                "id": "3.6.4.10",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10",
                "type": "external"
            },
            {
                "id": "5.6.2.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-",
                "type": "external"
            },
            {
                "id": "2.7.7.7",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7",
                "type": "external"
            },
            {
                "id": "2.7.7.49",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49",
                "type": "external"
            },
            {
                "id": "5.6.2.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5",
                "type": "external"
            },
            {
                "id": "3.6.5.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-",
                "type": "external"
            },
            {
                "id": "3.6.1.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004386 helicase activity",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0ACD6B6R7-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0ACD6B6R8-1",
        "uniprot_id": [
            {
                "id": "A0ACD6B6R8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B6R8",
                "type": "external"
            }
        ],
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        "length": 405,
        "protein_name": "Phosphoprotein associated with glycosphingolipid-enriched microdomains 1",
        "gene_name": "pag1",
        "organism": "Zebrafish",
        "refseq_name": "phosphoprotein associated with glycosphingolipid-enriched microdomains 1",
        "refseq_ac": [
            {
                "id": "XP_003200660",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200660",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pag1",
        "gene_names_refseq": "pag1",
        "protein_names_uniprotkb": "Phosphoprotein associated with glycosphingolipid-enriched microdomains 1",
        "protein_names_refseq": "phosphoprotein associated with glycosphingolipid-enriched microdomains 1",
        "tax_id": 7955,
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        "pathway": "",
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        "publication_count": 0,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_003200660.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 2,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0ACD6B6R9-1",
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            {
                "id": "A0ACD6B6R9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B6R9",
                "type": "external"
            }
        ],
        "mass": 44643.0,
        "length": 391,
        "protein_name": "Keratin 98 isoform X1",
        "gene_name": "krt98",
        "organism": "Zebrafish",
        "refseq_name": "keratin 98 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005155788",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155788",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "krt98; zgc:171226",
        "gene_names_refseq": "krt98; zgc:171226",
        "protein_names_uniprotkb": "Keratin 98 isoform X1",
        "protein_names_refseq": "keratin 98 isoform X1",
        "tax_id": 7955,
        "disease": "",
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        "pathway_count": 0,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005155788.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0005882 intermediate filament",
        "go_biological_process": "",
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0ACD6B6S3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B6S3",
                "type": "external"
            }
        ],
        "mass": 161384.0,
        "length": 1438,
        "protein_name": "SET-binding protein",
        "gene_name": "setbp1",
        "organism": "Zebrafish",
        "refseq_name": "SET-binding protein",
        "refseq_ac": [
            {
                "id": "XP_005165732",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165732",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "setbp1",
        "gene_names_refseq": "setbp1",
        "protein_names_uniprotkb": "SET-binding protein",
        "protein_names_refseq": "SET-binding protein",
        "tax_id": 7955,
        "disease": "autosomal dominant intellectual developmental disorder 29 (Disease Ontology:DOID:0070059); Schinzel Giedion syndrome (Disease Ontology:DOID:0070509)",
        "pathway": "",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005165732.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 2,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 2,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
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        "record_id": "A0ACD6B6S3-1",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0ACD6B6S7-1",
        "uniprot_id": [
            {
                "id": "A0ACD6B6S7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B6S7",
                "type": "external"
            }
        ],
        "mass": 13055.0,
        "length": 121,
        "protein_name": "C-X-C motif chemokine",
        "gene_name": "cxcl11.7",
        "organism": "Zebrafish",
        "refseq_name": "C-X-C motif chemokine 11-6",
        "refseq_ac": [
            {
                "id": "XP_005165469",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165469",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cxcl11.7",
        "gene_names_refseq": "cxcl11.7",
        "protein_names_uniprotkb": "C-X-C motif chemokine",
        "protein_names_refseq": "C-X-C motif chemokine 11-6",
        "tax_id": 7955,
        "disease": "pulmonary sarcoidosis (Disease Ontology:DOID:13406); bronchiolitis obliterans (Disease Ontology:DOID:2799); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083)",
        "pathway": "",
        "pathway_count": 0,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005165469.1. COMPLETENESS: full length., [RefSeq]; Ligand for cxcr3.2. Chemotactic for macrophages., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "reported_n_glycosites": 0,
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        "total_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
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        "kg_view_protein": true
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    {
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            {
                "id": "A0ACD6B6S8_DANRE",
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                "type": "external"
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        ],
        "mass": 60772.0,
        "length": 560,
        "protein_name": "Rap1 GTPase-GDP dissociation stimulator 1-B",
        "gene_name": "si:dkey-191g9.5",
        "organism": "Zebrafish",
        "refseq_name": "rap1 GTPase-GDP dissociation stimulator 1-B",
        "refseq_ac": [
            {
                "id": "XP_001921954",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001921954",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:dkey-191g9.5",
        "gene_names_refseq": "si:dkey-191g9.5",
        "protein_names_uniprotkb": "Rap1 GTPase-GDP dissociation stimulator 1-B",
        "protein_names_refseq": "rap1 GTPase-GDP dissociation stimulator 1-B",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001921954.3. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
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        "reported_n_glycosites": 0,
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        "total_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
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        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0ACD6B6T6-1",
        "uniprot_id": [
            {
                "id": "A0ACD6B6T6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B6T6",
                "type": "external"
            }
        ],
        "mass": 42522.0,
        "length": 380,
        "protein_name": "Cardiotrophin-like cytokine factor 1",
        "gene_name": "clcf1",
        "organism": "Zebrafish",
        "refseq_name": "cardiotrophin-like cytokine factor 1 precursor",
        "refseq_ac": [
            {
                "id": "NP_001429169",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429169",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "clcf1",
        "gene_names_refseq": "clcf1; si:dkey-6i22.4",
        "protein_names_uniprotkb": "Cardiotrophin-like cytokine factor 1; B-cell-stimulating factor 3; Novel neurotrophin-1",
        "protein_names_refseq": "cardiotrophin-like cytokine factor 1 precursor",
        "tax_id": 7955,
        "disease": "cold-induced sweating syndrome 2 (Disease Ontology:DOID:0080330); severe acute respiratory syndrome (Disease Ontology:DOID:2945)",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01023521.1, SRR32588732.33818157.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476733, SAMEA4476734 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Jul 30, 2025 this sequence version replaced XP_021336825.2. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; In complex with CRLF1, forms a heterodimeric neurotropic cytokine that plays a crucial role during neuronal development. Also stimulates B-cells. Binds to and activates the ILST/gp130 receptor., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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            {
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                "type": "external"
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_003200702.2. COMPLETENESS: full length., [RefSeq]",
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        "organism": "Zebrafish",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697468",
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        "gene_names_uniprotkb": "ggt1b",
        "gene_names_refseq": "ggt1b",
        "protein_names_uniprotkb": "Glutathione hydrolase; 2.3.2.2; 3.4.19.13; Gamma-glutamyltransferase; Gamma-glutamyltranspeptidase",
        "protein_names_refseq": "glutathione hydrolase 1 proenzyme",
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        "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); gamma-glutamyl transpeptidase deficiency (Disease Ontology:DOID:0111257); gestational diabetes (Disease Ontology:DOID:11714); biliary atresia (Disease Ontology:DOID:13608); melanoma (Disease Ontology:DOID:1909); liver cirrhosis (Disease Ontology:DOID:5082); hepatocellular carcinoma (Disease Ontology:DOID:684); diabetic retinopathy (Disease Ontology:DOID:8947); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); diabetic neuropathy (Disease Ontology:DOID:9743)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_697468.3. COMPLETENESS: full length., [RefSeq]; Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates., [UniProtKB, UniProtKB]",
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        "gene_names_refseq": "hdlbpb",
        "protein_names_uniprotkb": "Vigilin; High density lipoprotein-binding protein",
        "protein_names_refseq": "vigilin",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021335983.1. COMPLETENESS: full length., [RefSeq]; Appears to play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol., [UniProtKB, UniProtKB]",
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        ],
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        "gene_name": "zc3h7bb",
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        "protein_names_refseq": "zinc finger CCCH domain-containing protein 7B",
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        "length": 365,
        "protein_name": "Endoplasmic reticulum-Golgi intermediate compartment protein",
        "gene_name": "si:ch211-225b10.3",
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        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021336039",
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        "gene_names_refseq": "si:ch211-225b10.3",
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        "protein_names_refseq": "endoplasmic reticulum-Golgi intermediate compartment protein 2",
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        ],
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        "protein_name": "Tapasin-related protein",
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        ],
        "gene_names_uniprotkb": "dhrs13b.1; dhrs13b; si:ch211-108p6.4; tapbpr2; zgc:91936",
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        "gene_names_uniprotkb": "si:ch73-288o11.5",
        "gene_names_refseq": "si:ch73-288o11.5",
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        ],
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        "gene_name": "muc5.1",
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            },
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            },
            {
                "id": "3.1.1.5",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5",
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        ],
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        "gene_name": "uba7",
        "organism": "Zebrafish",
        "refseq_name": "ubiquitin-like modifier-activating enzyme 1",
        "refseq_ac": [
            {
                "id": "XP_005155933",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155933",
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            }
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        "gene_names_refseq": "uba7",
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        "protein_names_refseq": "ubiquitin-like modifier-activating enzyme 1",
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        ],
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        "length": 335,
        "protein_name": "P2Y purinoceptor 13",
        "gene_name": "p2ry13",
        "organism": "Zebrafish",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664563",
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        "gene_names_uniprotkb": "p2ry13",
        "gene_names_refseq": "p2ry13",
        "protein_names_uniprotkb": "P2Y purinoceptor 13",
        "protein_names_refseq": "P2Y purinoceptor 13",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_002664563.1. COMPLETENESS: full length., [RefSeq]",
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        ],
        "mass": 26085.0,
        "length": 245,
        "protein_name": "Membrane-spanning 4-domains subfamily A member 8",
        "gene_name": "si:dkey-77f5.10",
        "organism": "Zebrafish",
        "refseq_name": "membrane-spanning 4-domains subfamily A member 8",
        "refseq_ac": [
            {
                "id": "XP_003200040",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200040",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "si:dkey-77f5.10",
        "gene_names_refseq": "si:dkey-77f5.10",
        "protein_names_uniprotkb": "Membrane-spanning 4-domains subfamily A member 8",
        "protein_names_refseq": "membrane-spanning 4-domains subfamily A member 8",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_003200040.2. COMPLETENESS: full length., [RefSeq]",
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        ],
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        "protein_name": "Relaxin-3 receptor 1",
        "gene_name": "rxfp3.3b",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174282",
                "type": "external"
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        "gene_names_uniprotkb": "rxfp3.3b",
        "gene_names_refseq": "rxfp3.3b",
        "protein_names_uniprotkb": "Relaxin-3 receptor 1; Relaxin family peptide receptor 3",
        "protein_names_refseq": "relaxin-3 receptor 1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005174282.1. COMPLETENESS: full length., [RefSeq]; Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation., [UniProtKB, UniProtKB]",
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    {
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        "protein_name": "Uncharacterized protein lrtm2b",
        "gene_name": "lrtm2b",
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        "gene_names_uniprotkb": "lrtm2b",
        "gene_names_refseq": "lrtm2b",
        "protein_names_uniprotkb": "Uncharacterized protein lrtm2b",
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        ],
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        "length": 568,
        "protein_name": "Protein NDNF",
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        "organism": "Zebrafish",
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        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323101",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "ndnfl",
        "gene_names_refseq": "ndnfl",
        "protein_names_uniprotkb": "Protein NDNF",
        "protein_names_refseq": "protein NDNF",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021323101.1. COMPLETENESS: full length., [RefSeq]; Secretory protein that plays a role in various cellular processes. Acts as a chemorepellent acting on gonadotropin-releasing hormone (GnRH) expressing neurons regulating their migration to the hypothalamus. Also promotes neuron migration, growth and survival as well as neurite outgrowth and is involved in the development of the olfactory system. May also act through the regulation of growth factors activity and downstream signaling. Also regulates extracellular matrix assembly and cell adhesiveness. Promotes endothelial cell survival, vessel formation and plays an important role in the process of revascularization through NOS3-dependent mechanisms., [UniProtKB, UniProtKB]",
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        "gene_name": "ftr42",
        "organism": "Zebrafish",
        "refseq_name": "LOW QUALITY PROTEIN: tripartite motif-containing protein 16",
        "refseq_ac": [
            {
                "id": "XP_695550",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695550",
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        "refseq_ac": [
            {
                "id": "XP_021324071",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324071",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "bpnt1; zgc:92144",
        "gene_names_refseq": "bpnt1; zgc:92144",
        "protein_names_uniprotkb": "3'(2'),5'-bisphosphate nucleotidase 1; 3'-phosphoadenosine 5'-phosphate phosphatase; 3.1.3.57; 3.1.3.7; Bisphosphate 3'-nucleotidase 1; Inositol-polyphosphate 1-phosphatase",
        "protein_names_refseq": "3'(2'),5'-bisphosphate nucleotidase 1 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021324071.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "ec_number_list": [
            {
                "id": "3.1.3.57",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.57",
                "type": "external"
            },
            {
                "id": "3.1.3.7",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.7",
                "type": "external"
            }
        ],
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
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        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0ACD6B7E8-1",
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            {
                "id": "A0ACD6B7E8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B7E8",
                "type": "external"
            }
        ],
        "mass": 66725.0,
        "length": 612,
        "protein_name": "Uncharacterized protein tgoln2 isoform X1",
        "gene_name": "tgoln2",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein tgoln2 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_003199201",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003199201",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tgoln2",
        "gene_names_refseq": "tgoln2",
        "protein_names_uniprotkb": "Uncharacterized protein tgoln2 isoform X1",
        "protein_names_refseq": "uncharacterized protein tgoln2 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_003199201.2. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
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    {
        "uniprot_canonical_ac": "A0ACD6B7F2-1",
        "uniprot_id": [
            {
                "id": "A0ACD6B7F2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B7F2",
                "type": "external"
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        ],
        "mass": 157516.0,
        "length": 1462,
        "protein_name": "Uncharacterized protein si:dkeyp-69b9.6",
        "gene_name": "si:dkeyp-69b9.6",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:dkeyp-69b9.6",
        "refseq_ac": [
            {
                "id": "XP_021322542",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322542",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:dkeyp-69b9.6",
        "gene_names_refseq": "si:dkeyp-69b9.6",
        "protein_names_uniprotkb": "Uncharacterized protein si:dkeyp-69b9.6",
        "protein_names_refseq": "uncharacterized protein si:dkeyp-69b9.6",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322542.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
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        "missing_score": 10000,
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        "go_biological_process": "",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0ACD6B7F8-1",
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            {
                "id": "A0ACD6B7F8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B7F8",
                "type": "external"
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        ],
        "mass": 77252.0,
        "length": 702,
        "protein_name": "Neurochondrin",
        "gene_name": "ncdn",
        "organism": "Zebrafish",
        "refseq_name": "neurochondrin",
        "refseq_ac": [
            {
                "id": "XP_002667129",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002667129",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ncdn",
        "gene_names_refseq": "ncdn",
        "protein_names_uniprotkb": "Neurochondrin",
        "protein_names_refseq": "neurochondrin",
        "tax_id": 7955,
        "disease": "schizophrenia (Disease Ontology:DOID:5419)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_002667129.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "",
        "go_cellular_component": "",
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        "synthesized_glycan_count": 0,
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        "record_id": "A0ACD6B7F8-1",
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        "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0ACD6B7G4-1",
        "uniprot_id": [
            {
                "id": "A0ACD6B7G4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B7G4",
                "type": "external"
            }
        ],
        "mass": 146365.0,
        "length": 1281,
        "protein_name": "DNA-directed RNA polymerase",
        "gene_name": "polrmt",
        "organism": "Zebrafish",
        "refseq_name": "DNA-directed RNA polymerase, mitochondrial",
        "refseq_ac": [
            {
                "id": "XP_005170579",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170579",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "polrmt",
        "gene_names_refseq": "polrmt",
        "protein_names_uniprotkb": "DNA-directed RNA polymerase; 2.7.7.6",
        "protein_names_refseq": "DNA-directed RNA polymerase, mitochondrial",
        "tax_id": 7955,
        "disease": "combined oxidative phosphorylation deficiency 55 (Disease Ontology:DOID:0070428)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005170579.1. COMPLETENESS: full length., [RefSeq]; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates., [UniProtKB, UniProtKB]; DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA. In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand. Has DNA primase activity. Catalyzes the synthesis of short RNA primers that are necessary for the initiation of lagging-strand DNA synthesis from the origin of light-strand DNA replication (OriL)., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "ec_number_list": [
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6",
                "type": "external"
            }
        ],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0000428 DNA-directed RNA polymerase complex",
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        "synthesized_glycan_count": 0,
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        "kg_view_protein": true
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    {
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                "id": "A0ACD6B7H0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B7H0",
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        ],
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        "length": 256,
        "protein_name": "Uncharacterized protein si:ch73-281k2.5",
        "gene_name": "si:ch73-281k2.5",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch73-281k2.5",
        "refseq_ac": [
            {
                "id": "XP_009302182",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302182",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch73-281k2.5",
        "gene_names_refseq": "si:ch73-281k2.5",
        "protein_names_uniprotkb": "Uncharacterized protein si:ch73-281k2.5",
        "protein_names_refseq": "uncharacterized protein si:ch73-281k2.5",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009302182.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        ],
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        "protein_name": "EF-hand and coiled-coil domain-containing protein 1",
        "gene_name": "efcc1",
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        "refseq_name": "EF-hand and coiled-coil domain-containing protein 1",
        "refseq_ac": [
            {
                "id": "XP_002663835",
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        "protein_names_refseq": "EF-hand and coiled-coil domain-containing protein 1",
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                "id": "2.7.12.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2",
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                "type": "external"
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        "kg_view_protein": true
    },
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            {
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                "url": "https://www.uniprot.org/uniprot/A0ACD6B7J5",
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            }
        ],
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        "protein_name": "Cyclin-dependent kinase inhibitor 1C",
        "gene_name": "cdkn1cb",
        "organism": "Zebrafish",
        "refseq_name": "cyclin-dependent kinase inhibitor 1C",
        "refseq_ac": [
            {
                "id": "XP_001337196",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001337196",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cdkn1cb",
        "gene_names_refseq": "cdkn1cb",
        "protein_names_uniprotkb": "Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; p57Kip2",
        "protein_names_refseq": "cyclin-dependent kinase inhibitor 1C",
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        "disease": "IMAGe syndrome (Disease Ontology:DOID:0050885); pre-eclampsia (Disease Ontology:DOID:10591); hyperinsulinism (Disease Ontology:DOID:2018); Beckwith-Wiedemann syndrome (Disease Ontology:DOID:5572); hepatocellular carcinoma (Disease Ontology:DOID:684)",
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    {
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        ],
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        "length": 959,
        "protein_name": "Probable carboxypeptidase X1 isoform X1",
        "gene_name": "cpxm1b",
        "organism": "Zebrafish",
        "refseq_name": "probable carboxypeptidase X1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009289577",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009289577",
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        "gene_names_refseq": "cpxm1b",
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        "protein_names_refseq": "probable carboxypeptidase X1 isoform X1",
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            }
        ],
        "gene_names_uniprotkb": "zcchc14",
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        "protein_names_refseq": "zinc finger CCHC domain-containing protein 14",
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        ],
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691718",
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        ],
        "gene_names_uniprotkb": "btbd17a",
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        "protein_names_refseq": "BTB/POZ domain-containing protein 17 isoform X1",
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        "protein_name": "Nuclear factor 7, ovary",
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        "gene_names_refseq": "si:ch73-144l3.1",
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    {
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        ],
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        "gene_name": "orai1a",
        "organism": "Zebrafish",
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        "refseq_ac": [
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        "disease": "Stormorken syndrome (Disease Ontology:DOID:0060354); tubular aggregate myopathy 2 (Disease Ontology:DOID:0080686); immunodeficiency 9 (Disease Ontology:DOID:0111976)",
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        "gene_name": "rbm26",
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        ],
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        ],
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        "length": 632,
        "protein_name": "Uncharacterized protein si:dkey-172k15.19",
        "gene_name": "si:dkey-172k15.19",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:dkey-172k15.19",
        "refseq_ac": [
            {
                "id": "XP_002661910",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002661910",
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            }
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        "gene_names_uniprotkb": "si:dkey-172k15.19",
        "gene_names_refseq": "si:dkey-172k15.19",
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        "protein_names_refseq": "uncharacterized protein si:dkey-172k15.19",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_002661910.2. COMPLETENESS: full length., [RefSeq]",
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        "kg_view_protein": true
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    {
        "uniprot_canonical_ac": "A0ACD6B7Q5-1",
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            {
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                "url": "https://www.uniprot.org/uniprot/A0ACD6B7Q5",
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        ],
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        "length": 441,
        "protein_name": "Uncharacterized protein si:ch73-266f23.4",
        "gene_name": "si:ch73-266f23.4",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch73-266f23.4",
        "refseq_ac": [
            {
                "id": "XP_073804623",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073804623",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch73-266f23.4",
        "gene_names_refseq": "si:ch73-266f23.4",
        "protein_names_uniprotkb": "Uncharacterized protein si:ch73-266f23.4",
        "protein_names_refseq": "uncharacterized protein si:ch73-266f23.4",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
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    },
    {
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            {
                "id": "A0ACD6B7S1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B7S1",
                "type": "external"
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        ],
        "mass": 143453.0,
        "length": 1303,
        "protein_name": "Cadherin-related family member 1",
        "gene_name": "cdhr2",
        "organism": "Zebrafish",
        "refseq_name": "cadherin-related family member 2 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_073778418",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073778418",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cdhr2",
        "gene_names_refseq": "cdhr2",
        "protein_names_uniprotkb": "Cadherin-related family member 1; Photoreceptor cadherin; Protocadherin-21",
        "protein_names_refseq": "cadherin-related family member 2 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 2,
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    {
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        ],
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        "protein_name": "Interleukin-1 receptor type 1 isoform X1",
        "gene_name": "il1rl2",
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        "refseq_name": "interleukin-1 receptor type 1 isoform X1",
        "refseq_ac": [
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                "id": "XP_001339654",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001339654",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "il1rl2",
        "gene_names_refseq": "il1rl2",
        "protein_names_uniprotkb": "Interleukin-1 receptor type 1 isoform X1",
        "protein_names_refseq": "interleukin-1 receptor type 1 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001339654.4. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "kg_view_protein": true
    },
    {
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            {
                "id": "A0ACD6B7S4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B7S4",
                "type": "external"
            }
        ],
        "mass": 39647.0,
        "length": 346,
        "protein_name": "Very-long-chain enoyl-CoA reductase",
        "gene_name": "tecra",
        "organism": "Zebrafish",
        "refseq_name": "very-long-chain enoyl-CoA reductase",
        "refseq_ac": [
            {
                "id": "XP_001921351",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001921351",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tecra",
        "gene_names_refseq": "tecra",
        "protein_names_uniprotkb": "Very-long-chain enoyl-CoA reductase; 1.3.1.93; Synaptic glycoprotein SC2; Trans-2,3-enoyl-CoA reductase",
        "protein_names_refseq": "very-long-chain enoyl-CoA reductase",
        "tax_id": 7955,
        "disease": "autosomal recessive intellectual developmental disorder 14 (Disease Ontology:DOID:0081188)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001921351.1. COMPLETENESS: full length., [RefSeq]; Involved in both the production of very long-chain fatty acids for sphingolipid synthesis and the degradation of the sphingosine moiety in sphingolipids through the sphingosine 1-phosphate metabolic pathway. Catalyzes the last of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme reduces the trans-2,3-enoyl-CoA fatty acid intermediate to an acyl-CoA that can be further elongated by entering a new cycle of elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Catalyzes the saturation step of the sphingosine 1-phosphate metabolic pathway, the conversion of trans-2-hexadecenoyl-CoA to palmitoyl-CoA., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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                "id": "1.3.1.93",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.93",
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            }
        ],
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        "kg_view_protein": true
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    {
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        ],
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        "protein_name": "Protocadherin gamma-C3",
        "gene_name": "LOC100006777",
        "organism": "Zebrafish",
        "refseq_name": "protocadherin-10",
        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021335004",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "LOC100006777",
        "gene_names_refseq": "LOC100006777",
        "protein_names_uniprotkb": "Protocadherin gamma-C3",
        "protein_names_refseq": "protocadherin-10",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021335004.1. COMPLETENESS: full length., [RefSeq]",
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    {
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            {
                "id": "A0ACD6B7W6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0ACD6B7W6",
                "type": "external"
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        ],
        "mass": 104341.0,
        "length": 941,
        "protein_name": "Netrin receptor UNC5",
        "gene_name": "unc5db",
        "organism": "Zebrafish",
        "refseq_name": "netrin receptor UNC5D isoform X1",
        "refseq_ac": [
            {
                "id": "XP_001342230",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001342230",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "unc5db",
        "gene_names_refseq": "unc5db",
        "protein_names_uniprotkb": "Netrin receptor UNC5",
        "protein_names_refseq": "netrin receptor UNC5D isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001342230.2. COMPLETENESS: full length., [RefSeq]; Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding., [UniProtKB, UniProtKB, UniProtKB]",
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        "ec_number_list": [],
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        "go_biological_process": "",
        "synthesized_glycan_count": 0,
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        "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000",
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    {
        "uniprot_canonical_ac": "A0AC58JRZ2-1",
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            {
                "id": "A0AC58JRZ2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AC58JRZ2",
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        ],
        "mass": 1299409.0,
        "length": 12780,
        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC141386138",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": [
            {
                "id": "XP_073809233",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073809233",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "LOC141386138",
        "gene_names_refseq": "LOC141386138",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "record_id": "A0AC58JRZ2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.000010.000000000000000001.0000000000000.000.00000",
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    {
        "uniprot_canonical_ac": "A0AC58JS72-1",
        "uniprot_id": [
            {
                "id": "A0AC58JS72_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AC58JS72",
                "type": "external"
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        ],
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        "length": 334,
        "protein_name": "Regulator of G-protein signaling 4",
        "gene_name": "rgs4",
        "organism": "Zebrafish",
        "refseq_name": "regulator of G-protein signaling 4 isoform 2",
        "refseq_ac": [
            {
                "id": "NP_001429061",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429061",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "rgs4; cb436; sb:cb436; wu:fc06d08",
        "gene_names_refseq": "cb436; rgs4; sb:cb436; wu:fc06d08",
        "protein_names_uniprotkb": "Regulator of G-protein signaling 4",
        "protein_names_refseq": "regulator of G-protein signaling 4 isoform 2; regulator of G-protein signalling 4",
        "tax_id": 7955,
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        "publication_id_list": "21911471;23052218",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588718.21343200.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On Jul 28, 2025 this sequence version replaced XP_073809327.1., [RefSeq]; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein., [UniProtKB, UniProtKB, UniProtKB]; Rgs4 is expressed in endocrine progenitors of both zebrafish and mouse, and its expression in the mouse pancreatic epithelium is strictly dependent upon Ngn3, and loss of function of Rgs4 results in islet fragmentation in both organisms., [RefSeq, PubMed]; Rgs4 knockdown also attenuated the level of phosphorylated-Akt1, and injection of constitutively-activated AKT1 rescued the motility defects and axonal phenotypes in the spinal cord but not in the hindbrain and trigeminal neurons., [RefSeq, PubMed]",
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        "gene_name": "spega",
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        "gene_names_refseq": "apeg1; fc31c10; im:6912258; spega; speg; wu:fc31c10",
        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
        "protein_names_refseq": "striated muscle preferentially expressed protein kinase isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 4,
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24",
                "type": "external"
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            {
                "id": "2.7.10.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2",
                "type": "external"
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            {
                "id": "2.7.11.23",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23",
                "type": "external"
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            {
                "id": "2.7.1.150",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150",
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            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12",
                "type": "external"
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            {
                "id": "2.7.11.39",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39",
                "type": "external"
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            {
                "id": "2.7.11.11",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11",
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            {
                "id": "2.7.1.153",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153",
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                "id": "2.7.1.137",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137",
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                "id": "2.7.1.154",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26",
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            {
                "id": "2.7.11.31",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31",
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        ],
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    {
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        "uniprot_id": [
            {
                "id": "A0AC58JSS5_DANRE",
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        ],
        "mass": 83045.0,
        "length": 743,
        "protein_name": "Solute carrier family 15 member 1",
        "gene_name": "slc15a1b",
        "organism": "Zebrafish",
        "refseq_name": "solute carrier family 15 member 1b isoform X1",
        "refseq_ac": [
            {
                "id": "XP_073809503",
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        ],
        "gene_names_uniprotkb": "slc15a1b; PEPT1; fd47f07; slc15a1; wu:fd47f07",
        "gene_names_refseq": "PEPT1; fd47f07; slc15a1b; slc15a1; wu:fd47f07",
        "protein_names_uniprotkb": "Solute carrier family 15 member 1; Intestinal H(+)/peptide cotransporter; Oligopeptide transporter, small intestine isoform; Peptide transporter 1",
        "protein_names_refseq": "solute carrier family 15 member 1b isoform X1",
        "tax_id": 7955,
        "disease": "obesity (Disease Ontology:DOID:9970)",
        "pathway": "",
        "pathway_count": 0,
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        "publication_id_list": "12914936;16317081;17059815;18804112;19253392;35853004;36065184;36318514;36396123;37342912",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Electrogenic proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Transports neutral and monovalently charged peptides with a proton to peptide stoichiometry of 1:1 or 2:1. Primarily responsible for the absorption of dietary di- and tripeptides from the small intestinal lumen. Mediates transepithelial transport of muramyl and N-formylated bacterial dipeptides contributing to recognition of pathogenic bacteria by the mucosal immune system., [UniProtKB, UniProtKB, UniProtKB]",
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        "gene_name": "LOC137495831",
        "organism": "Zebrafish",
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        "refseq_ac": [
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        ],
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        "gene_name": "si:ch211-69b7.6",
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        "gene_names_refseq": "cd59b",
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        "gene_names_uniprotkb": "pde4ba",
        "gene_names_refseq": "pde4ba",
        "protein_names_uniprotkb": "Phosphodiesterase; 3.1.4.-",
        "protein_names_refseq": "3',5'-cyclic-AMP phosphodiesterase 4B isoform X1",
        "tax_id": 7955,
        "disease": "alcohol dependence (Disease Ontology:DOID:0050741); depressive disorder (Disease Ontology:DOID:1596)",
        "pathway": " (dre:565706)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "total_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 1,
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        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "3.1.4.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-",
                "type": "external"
            },
            {
                "id": "3.1.4.53",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.53",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0046872 metal ion binding;GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity;GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity",
        "go_cellular_component": "",
        "go_biological_process": "GO:0007165 signal transduction;GO:0006198 cAMP catabolic process;GO:0141162 negative regulation of cAMP/PKA signal transduction",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58JV44-1",
        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AA53ECX7-1",
        "uniprot_id": [
            {
                "id": "A0AA53ECX7_DANRE",
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        ],
        "mass": 35681.0,
        "length": 324,
        "protein_name": "Hepatitis A virus cellular receptor 1 isoform X1",
        "gene_name": "havcr1",
        "organism": "Zebrafish",
        "refseq_name": "hepatitis A virus cellular receptor 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005161402",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161402",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "havcr1; DrTIM-4; TIM-1; Tim-4; kim1; kim4; timd1; wu:fb01b10; zgc:92647",
        "gene_names_refseq": "DrTIM-4; TIM-1; Tim-4; havcr1; kim1; kim4; timd1; wu:fb01b10; zgc:92647",
        "protein_names_uniprotkb": "Hepatitis A virus cellular receptor 1 isoform X1",
        "protein_names_refseq": "hepatitis A virus cellular receptor 1 isoform X1",
        "tax_id": 7955,
        "disease": "essential hypertension (Disease Ontology:DOID:10825); hydronephrosis (Disease Ontology:DOID:11111); acute kidney tubular necrosis (Disease Ontology:DOID:12556); renovascular hypertension (Disease Ontology:DOID:1591); hyperuricemia (Disease Ontology:DOID:1920); relapsing-remitting multiple sclerosis (Disease Ontology:DOID:2378); asthma (Disease Ontology:DOID:2841); IgA glomerulonephritis (Disease Ontology:DOID:2986); acute kidney failure (Disease Ontology:DOID:3021); atopic dermatitis (Disease Ontology:DOID:3310); renal cell carcinoma (Disease Ontology:DOID:4450); kidney disease (Disease Ontology:DOID:557); hepatocellular carcinoma (Disease Ontology:DOID:684); vesicoureteral reflux (Disease Ontology:DOID:9620)",
        "pathway": "",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005161402.1. COMPLETENESS: full length., [RefSeq]",
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        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0016020 membrane",
        "go_biological_process": "GO:0043277 apoptotic cell clearance;GO:0043652 engulfment of apoptotic cell;GO:0060097 cytoskeletal rearrangement involved in phagocytosis, engulfment",
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    },
    {
        "uniprot_canonical_ac": "A0A8M3AJU9-1",
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            {
                "id": "A0A8M3AJU9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M3AJU9",
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        ],
        "mass": 100710.0,
        "length": 897,
        "protein_name": "Mitogen-activated protein kinase kinase kinase kinase",
        "gene_name": "map4k3b",
        "organism": "Zebrafish",
        "refseq_name": "mitogen-activated protein kinase kinase kinase kinase 3 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009291338",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009291338",
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        ],
        "gene_names_uniprotkb": "map4k3b",
        "gene_names_refseq": "map4k3b",
        "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase kinase; 2.7.11.1",
        "protein_names_refseq": "mitogen-activated protein kinase kinase kinase kinase 3 isoform X1",
        "tax_id": 7955,
        "disease": "ciliopathy (Disease Ontology:DOID:0060340); alcohol use disorder (Disease Ontology:DOID:1574)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009291338.1. COMPLETENESS: full length., [RefSeq]; Serine/threonine kinase that plays a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "ec_number_list": [
            {
                "id": "2.7.11.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
                "type": "external"
            },
            {
                "id": "2.7.11.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13",
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            {
                "id": "2.7.11.25",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25",
                "type": "external"
            },
            {
                "id": "2.7.10.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1",
                "type": "external"
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            {
                "id": "2.7.11.22",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22",
                "type": "external"
            },
            {
                "id": "2.7.11.21",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21",
                "type": "external"
            },
            {
                "id": "2.7.11.17",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17",
                "type": "external"
            },
            {
                "id": "2.7.12.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1",
                "type": "external"
            },
            {
                "id": "2.7.12.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2",
                "type": "external"
            },
            {
                "id": "2.7.11.24",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24",
                "type": "external"
            },
            {
                "id": "2.7.10.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2",
                "type": "external"
            },
            {
                "id": "2.7.11.23",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23",
                "type": "external"
            },
            {
                "id": "2.7.1.150",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150",
                "type": "external"
            },
            {
                "id": "2.7.11.12",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12",
                "type": "external"
            },
            {
                "id": "2.7.11.39",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39",
                "type": "external"
            },
            {
                "id": "2.7.11.11",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11",
                "type": "external"
            },
            {
                "id": "2.7.1.153",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153",
                "type": "external"
            },
            {
                "id": "2.7.1.137",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137",
                "type": "external"
            },
            {
                "id": "2.7.1.154",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154",
                "type": "external"
            },
            {
                "id": "2.7.11.26",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26",
                "type": "external"
            },
            {
                "id": "2.7.11.31",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0005524 ATP binding;GO:0008349 MAP kinase kinase kinase kinase activity;GO:0016301 kinase activity",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M3AJU9-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M2B960-1",
        "uniprot_id": [
            {
                "id": "A0A8M2B960_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M2B960",
                "type": "external"
            }
        ],
        "mass": 498054.0,
        "length": 4569,
        "protein_name": "E3 ubiquitin-protein ligase HUWE1",
        "gene_name": "huwe1",
        "organism": "Zebrafish",
        "refseq_name": "E3 ubiquitin-protein ligase HUWE1 isoform 1",
        "refseq_ac": [
            {
                "id": "NP_001352583",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352583",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "huwe1; sb:eu595; sb:eu633; sb:eu703; si:dkey-242a8.2",
        "gene_names_refseq": "huwe1; sb:eu595; sb:eu633; sb:eu703; si:dkey-242a8.2",
        "protein_names_uniprotkb": "E3 ubiquitin-protein ligase HUWE1; 2.3.2.26; HECT, UBA and WWE domain-containing protein 1; HECT-type E3 ubiquitin transferase HUWE1; Upstream regulatory element-binding protein 1",
        "protein_names_refseq": "E3 ubiquitin-protein ligase HUWE1 isoform 1; HECT, UBA and WWE domain containing 1",
        "tax_id": 7955,
        "disease": "syndromic X-linked intellectual disability (Disease Ontology:DOID:0060309); syndromic X-linked intellectual disability Turner type (Disease Ontology:DOID:0060811); non-syndromic X-linked intellectual disability 50 (Disease Ontology:DOID:0112029)",
        "pathway": " (dre:559439)",
        "pathway_count": 1,
        "publication_count": 8,
        "publication_id_list": "26469318;27189481;27215328;28252024;29344929;32703943;39021799;40044042",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01013033.1, SRR26395039.1839847.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476731, SAMEA4476732 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Jun 25, 2025 this sequence version replaced NP_001352583.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
        "predicted_glycosites": 6,
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        "secondary_ac_list": "A0AC58IK23",
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        "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0000139 Golgi membrane;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006281 DNA repair;GO:0030154 cell differentiation;GO:0016567 protein ubiquitination;GO:0048511 rhythmic process;GO:0006284 base-excision repair",
        "synthesized_glycan_count": 0,
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        "filter_code": "0000000.0000111.001000.000000000000000001.0100000001000.001.00000",
        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0AC58JVG2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AC58JVG2",
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        ],
        "mass": 124904.0,
        "length": 1108,
        "protein_name": "Anion exchange protein",
        "gene_name": "slc4a8",
        "organism": "Zebrafish",
        "refseq_name": "electroneutral sodium bicarbonate exchanger 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_073810480",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073810480",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "slc4a8",
        "gene_names_refseq": "slc4a8",
        "protein_names_uniprotkb": "Anion exchange protein",
        "protein_names_refseq": "electroneutral sodium bicarbonate exchanger 1 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:557494);  (R-DRE-425381)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "predicted_c_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008509 monoatomic anion transmembrane transporter activity;GO:0015081 sodium ion transmembrane transporter activity;GO:0005452 solute:inorganic anion antiporter activity;GO:0015106 bicarbonate transmembrane transporter activity;GO:0008510 sodium:bicarbonate symporter activity",
        "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0055085 transmembrane transport;GO:0015701 bicarbonate transport;GO:0051453 regulation of intracellular pH",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58JVG2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000001.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M2BHF6-1",
        "uniprot_id": [
            {
                "id": "A0A8M2BHF6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M2BHF6",
                "type": "external"
            }
        ],
        "mass": 54075.0,
        "length": 500,
        "protein_name": "Glutathione reductase",
        "gene_name": "gsr",
        "organism": "Zebrafish",
        "refseq_name": "glutathione reductase, mitochondrial isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005169649",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169649",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "gsr; zgc:110010",
        "gene_names_refseq": "gsr; zgc:110010",
        "protein_names_uniprotkb": "Glutathione reductase; 1.8.1.7",
        "protein_names_refseq": "glutathione reductase, mitochondrial isoform X1",
        "tax_id": 7955,
        "disease": "hemorrhagic cystitis (Disease Ontology:DOID:0050859); congenital nonspherocytic hemolytic anemia 10 (Disease Ontology:DOID:0051009); myoglobinuria (Disease Ontology:DOID:0080108); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); Parkinsonism (Disease Ontology:DOID:0080855); Heinz body anemia (Disease Ontology:DOID:0111363); lymphoid leukemia (Disease Ontology:DOID:1037); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); osteoporosis (Disease Ontology:DOID:11476); diabetic angiopathy (Disease Ontology:DOID:11713); limb-girdle muscular dystrophy (Disease Ontology:DOID:11724); iron deficiency anemia (Disease Ontology:DOID:11758); beta thalassemia (Disease Ontology:DOID:12241); acute kidney tubular necrosis (Disease Ontology:DOID:12556); Huntington's disease (Disease Ontology:DOID:12858); dementia (Disease Ontology:DOID:1307); diabetic cataract (Disease Ontology:DOID:13328); transient cerebral ischemia (Disease Ontology:DOID:224); acute kidney failure (Disease Ontology:DOID:3021); coronary artery disease (Disease Ontology:DOID:3393); macular degeneration (Disease Ontology:DOID:4448); renal cell carcinoma (Disease Ontology:DOID:4450); myocardial infarction (Disease Ontology:DOID:5844); nephrolithiasis (Disease Ontology:DOID:585); congenital hemolytic anemia (Disease Ontology:DOID:589); peptic ulcer disease (Disease Ontology:DOID:750); end stage renal disease (Disease Ontology:DOID:783); hyperthyroidism (Disease Ontology:DOID:7998); cataract (Disease Ontology:DOID:83); alcoholic gastritis (Disease Ontology:DOID:8680); polycythemia vera (Disease Ontology:DOID:8997); acute myeloid leukemia (Disease Ontology:DOID:9119); diabetes mellitus (Disease Ontology:DOID:9351); senile cataract (Disease Ontology:DOID:9669); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)",
        "pathway": "",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005169649.1. COMPLETENESS: full length., [RefSeq]; Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH). Constitutes the major mechanism to maintain a high GSH:GSSG ratio in the cytosol., [UniProtKB, UniProtKB, UniProtKB]",
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        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "1.8.1.7",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.1.7",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0050661 NADP binding;GO:0004362 glutathione-disulfide reductase (NADPH) activity",
        "go_cellular_component": "GO:0005739 mitochondrion",
        "go_biological_process": "GO:0045454 cell redox homeostasis;GO:0006749 glutathione metabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M2BHF6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AA54FRM3-1",
        "uniprot_id": [
            {
                "id": "A0AA54FRM3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA54FRM3",
                "type": "external"
            }
        ],
        "mass": 35353.0,
        "length": 311,
        "protein_name": "DnaJ homolog subfamily B member 6b isoform X1",
        "gene_name": "dnajb6b",
        "organism": "Zebrafish",
        "refseq_name": "dnaJ homolog subfamily B member 6b isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009301640",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301640",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "dnajb6b; dnajb6; zgc:56709",
        "gene_names_refseq": "dnajb6b; dnajb6; zgc:56709",
        "protein_names_uniprotkb": "DnaJ homolog subfamily B member 6b isoform X1",
        "protein_names_refseq": "dnaJ homolog subfamily B member 6b isoform X1",
        "tax_id": 7955,
        "disease": "autosomal dominant limb-girdle muscular dystrophy type 1 (Disease Ontology:DOID:0110305)",
        "pathway": "",
        "pathway_count": 0,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009301640.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "reported_phosphosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0AC58FXV8",
        "ec_number_list": [],
        "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0030544 Hsp70 protein binding",
        "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0003231 cardiac ventricle development;GO:0007626 locomotory behavior;GO:0010821 regulation of mitochondrion organization;GO:0007519 skeletal muscle tissue development;GO:0030239 myofibril assembly",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AA54FRM3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AA53EBK1-1",
        "uniprot_id": [
            {
                "id": "A0AA53EBK1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA53EBK1",
                "type": "external"
            }
        ],
        "mass": 27761.0,
        "length": 257,
        "protein_name": "Protein-L-isoaspartate O-methyltransferase",
        "gene_name": "pcmtl",
        "organism": "Zebrafish",
        "refseq_name": "l-isoaspartyl protein carboxyl methyltransferase, like isoform X1",
        "refseq_ac": [
            {
                "id": "XP_073783166",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073783166",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pcmtl; zgc:73268",
        "gene_names_refseq": "pcmtl; zgc:73268",
        "protein_names_uniprotkb": "Protein-L-isoaspartate O-methyltransferase; 2.1.1.77",
        "protein_names_refseq": "l-isoaspartyl protein carboxyl methyltransferase, like isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:393741)",
        "pathway_count": 1,
        "publication_count": 4,
        "publication_id_list": "15520368;27189481;28252024;33552132",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "predicted_s_glycosites": 0,
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        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "A0AC58HMF8",
        "ec_number_list": [
            {
                "id": "2.1.1.77",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.77",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity;GO:0008168 methyltransferase activity",
        "go_cellular_component": "",
        "go_biological_process": "GO:0032259 methylation;GO:0050848 regulation of calcium-mediated signaling",
        "synthesized_glycan_count": 0,
        "hit_score": 0.5,
        "record_id": "A0AA53EBK1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AB32T509-1",
        "uniprot_id": [
            {
                "id": "A0AB32T509_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32T509",
                "type": "external"
            }
        ],
        "mass": 60248.0,
        "length": 543,
        "protein_name": "T-box transcription factor TBX4 isoform X1",
        "gene_name": "tbx4",
        "organism": "Zebrafish",
        "refseq_name": "T-box transcription factor TBX4",
        "refseq_ac": [
            {
                "id": "NP_570989",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_570989",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tbx4",
        "gene_names_refseq": "tbx4",
        "protein_names_uniprotkb": "T-box transcription factor TBX4 isoform X1",
        "protein_names_refseq": "T-box 4; T-box gene 4; T-box transcription factor TBX4; pelvic finless; pfl; unm_zf358",
        "tax_id": 7955,
        "disease": "ischiocoxopodopatellar syndrome (Disease Ontology:DOID:0111382); arthropathy (Disease Ontology:DOID:381)",
        "pathway": " (dre:30070)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "12768655;16109975;18815807;19345202;21344479;23737474;26892237;27974754;31330852;33829511",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: AF179406.1, BC162554.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476739, SAMEA4476754 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jun 25, 2025 this sequence version replaced NP_570989.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 2,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 2,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "total_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "glyco_site_count": 2,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000785 chromatin",
        "go_biological_process": "GO:0001708 cell fate specification;GO:0060429 epithelium development;GO:0001525 angiogenesis;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0AB32T509-1",
        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9PN27-1",
        "uniprot_id": [
            {
                "id": "A0A8M9PN27_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9PN27",
                "type": "external"
            }
        ],
        "mass": 125839.0,
        "length": 1112,
        "protein_name": "PHD finger protein 20-like protein 1",
        "gene_name": "phf20l1",
        "organism": "Zebrafish",
        "refseq_name": "PHD finger protein 20-like protein 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009290756",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290756",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "phf20l1",
        "gene_names_refseq": "phf20l1",
        "protein_names_uniprotkb": "PHD finger protein 20-like protein 1",
        "protein_names_refseq": "PHD finger protein 20-like protein 1 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009290756.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "gene_name": "bbx",
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        "protein_names_refseq": "HMG box transcription factor BBX isoform X1",
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        "gene_name": "trappc8",
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        "refseq_ac": [
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    {
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            {
                "id": "A0A8M9PZU9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9PZU9",
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        ],
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        "length": 405,
        "protein_name": "Lymphocyte cytosolic protein 2 isoform X1",
        "gene_name": "lcp2b",
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        "refseq_ac": [
            {
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        "protein_names_refseq": "lymphocyte cytosolic protein 2 isoform X1",
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    {
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                "id": "A0A8M9Q0P0_DANRE",
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        ],
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        "gene_name": "hbl1",
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        "gene_names_uniprotkb": "hbl1",
        "gene_names_refseq": "hbl1",
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        "protein_names_refseq": "uncharacterized protein hbl1 isoform X1",
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        "disease": "invasive aspergillosis (Disease Ontology:DOID:0050073); disease by infectious agent (Disease Ontology:DOID:0050117); Kartagener syndrome (Disease Ontology:DOID:0050144); chorioamnionitis (Disease Ontology:DOID:0050697); respiratory allergy (Disease Ontology:DOID:0060496); Cryptococcal meningitis (Disease Ontology:DOID:0080159); lupus nephritis (Disease Ontology:DOID:0080162); Coronavirus infectious disease (Disease Ontology:DOID:0080599); sensorineural hearing loss (Disease Ontology:DOID:10003); dermatomyositis (Disease Ontology:DOID:10223); bacterial infectious disease (Disease Ontology:DOID:104); Legionnaires' disease (Disease Ontology:DOID:10457); Alzheimer's disease (Disease Ontology:DOID:10652); primary open angle glaucoma (Disease Ontology:DOID:1070); otitis media (Disease Ontology:DOID:10754); lepromatous leprosy (Disease Ontology:DOID:10887); respiratory failure (Disease Ontology:DOID:11162); adult respiratory distress syndrome (Disease Ontology:DOID:11394); bronchopulmonary dysplasia (Disease Ontology:DOID:11650); common variable immunodeficiency (Disease Ontology:DOID:12177); vitiligo (Disease Ontology:DOID:12306); bronchopneumonia (Disease Ontology:DOID:12375); hemolytic-uremic syndrome (Disease Ontology:DOID:12554); newborn respiratory distress syndrome (Disease Ontology:DOID:12716); allergic bronchopulmonary aspergillosis (Disease Ontology:DOID:13166); lung cancer (Disease Ontology:DOID:1324); Behcet's disease (Disease Ontology:DOID:13241); temporal arteritis (Disease Ontology:DOID:13375); Kawasaki disease (Disease Ontology:DOID:13378); coccidioidomycosis (Disease Ontology:DOID:13450); Plasmodium falciparum malaria (Disease Ontology:DOID:14067); toxic shock syndrome (Disease Ontology:DOID:14115); cystic fibrosis (Disease Ontology:DOID:1485); fungal infectious disease (Disease Ontology:DOID:1564); thrombocytopenia (Disease Ontology:DOID:1588); cryptosporidiosis (Disease Ontology:DOID:1733); hepatitis C (Disease Ontology:DOID:1883); hepatitis B (Disease Ontology:DOID:2043); vulvovaginal candidiasis (Disease Ontology:DOID:2272); leptospirosis (Disease Ontology:DOID:2297); ovarian cancer (Disease Ontology:DOID:2394); bronchiolitis obliterans (Disease Ontology:DOID:2799); asthma (Disease Ontology:DOID:2841); pulmonary tuberculosis (Disease Ontology:DOID:2957); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); atopic dermatitis (Disease Ontology:DOID:3310); bipolar disorder (Disease Ontology:DOID:3312); bacterial vaginosis (Disease Ontology:DOID:3385); peripheral vascular disease (Disease Ontology:DOID:341); pulmonary fibrosis (Disease Ontology:DOID:3770); liver disease (Disease Ontology:DOID:409); coronary restenosis (Disease Ontology:DOID:4247); rhinitis (Disease Ontology:DOID:4483); liver cirrhosis (Disease Ontology:DOID:5082); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); pneumonia (Disease Ontology:DOID:552); aortic valve insufficiency (Disease Ontology:DOID:57); panic disorder (Disease Ontology:DOID:594); systemic juvenile rheumatoid arthritis (Disease Ontology:DOID:676); hepatocellular carcinoma (Disease Ontology:DOID:684); autoimmune thyroiditis (Disease Ontology:DOID:7188); end stage renal disease (Disease Ontology:DOID:783); polymyalgia rheumatica (Disease Ontology:DOID:853); herpes simplex (Disease Ontology:DOID:8566); bacterial pneumonia (Disease Ontology:DOID:874); Crohn's disease (Disease Ontology:DOID:8778); psoriasis (Disease Ontology:DOID:8893); systemic lupus erythematosus (Disease Ontology:DOID:9074); visceral leishmaniasis (Disease Ontology:DOID:9146); pemphigus (Disease Ontology:DOID:9182); bronchiectasis (Disease Ontology:DOID:9563); obesity (Disease Ontology:DOID:9970)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021326930.2. COMPLETENESS: full length., [RefSeq]",
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        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
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                "id": "A0A8M9QG13_DANRE",
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        ],
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        "length": 244,
        "protein_name": "Testis-expressed protein 30 isoform X1",
        "gene_name": "tex30",
        "organism": "Zebrafish",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334631",
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        ],
        "gene_names_uniprotkb": "tex30",
        "gene_names_refseq": "tex30",
        "protein_names_uniprotkb": "Testis-expressed protein 30 isoform X1",
        "protein_names_refseq": "testis-expressed protein 30 isoform X1",
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    {
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        "uniprot_id": [
            {
                "id": "A0AA70QFV6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA70QFV6",
                "type": "external"
            }
        ],
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        "length": 346,
        "protein_name": "Uncharacterized protein ccdc50b isoform X1",
        "gene_name": "ccdc50b",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein ccdc50b isoform X1",
        "refseq_ac": [
            {
                "id": "XP_690155",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690155",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "ccdc50b",
        "gene_names_refseq": "ccdc50b",
        "protein_names_uniprotkb": "Uncharacterized protein ccdc50b isoform X1",
        "protein_names_refseq": "uncharacterized protein ccdc50b isoform X1",
        "tax_id": 7955,
        "disease": "mantle cell lymphoma (Disease Ontology:DOID:0050746); autosomal dominant nonsyndromic deafness 44 (Disease Ontology:DOID:0110569)",
        "pathway": " (dre:561649)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_690155.4. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        ],
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        "protein_name": "Calcium-activated chloride channel regulator 1 isoform X1",
        "gene_name": "clca1",
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        "refseq_name": "calcium-activated chloride channel regulator 1 isoform X1",
        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069577",
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        "gene_names_refseq": "clca1; fi39d11; wu:fi39d11",
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        "disease": "cystic fibrosis (Disease Ontology:DOID:1485); asthma (Disease Ontology:DOID:2841); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083)",
        "pathway": " (dre:334289);  (R-DRE-2672351)",
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        "protein_name": "Probable G-protein coupled receptor 142 isoform X1",
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        "mass": 69973.0,
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        "protein_name": "LIM domain-binding protein 3a isoform 2",
        "gene_name": "ldb3a",
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            {
                "id": "NP_001417805",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417805",
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        ],
        "gene_names_uniprotkb": "ldb3a; ZASP; cypher; hm:zehn1639; ldb3; zehn1639",
        "gene_names_refseq": "ZASP; cypher; hm:zehn1639; ldb3a; ldb3; zehn1639",
        "protein_names_uniprotkb": "LIM domain-binding protein 3a isoform 2",
        "protein_names_refseq": "LIM domain-binding protein 3a isoform 2; LIM-domain binding factor 3, like; LIM-domain binding factor 3a",
        "tax_id": 7955,
        "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); myofibrillar myopathy 1 (Disease Ontology:DOID:0080092); myofibrillar myopathy 4 (Disease Ontology:DOID:0080095); congenital myopathy (Disease Ontology:DOID:0081337); dilated cardiomyopathy 1C (Disease Ontology:DOID:0110423); distal myopathy (Disease Ontology:DOID:11720); myotonic dystrophy type 1 (Disease Ontology:DOID:11722); dilated cardiomyopathy (Disease Ontology:DOID:12930); myopathy (Disease Ontology:DOID:423)",
        "pathway": " (dre:794339)",
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        "publication_id_list": "15693615;16109975;16982050;17937393;22767232;28077310;29872120;30611731;32762296;37029137",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01021763.1, DQ012157.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505392, SAMEA4476744 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On Jun 25, 2025 this sequence version replaced NP_001417805.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Cypher may play a role downstream of sonic hedgehog, in a late stage of somite development, when slow muscle fibers differentiate and migrate from the adaxial cells., [RefSeq, PubMed]; Findings show the temporal & spatial expression patterns of the 3 Enigma family members & their PDZ & LIM domain encoding splice forms during embryogenesis, [RefSeq, PubMed]",
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        "go_cellular_component": "GO:0030018 Z disc;GO:0005912 adherens junction;GO:0001725 stress fiber;GO:0031941 filamentous actin",
        "go_biological_process": "GO:0007507 heart development;GO:0007626 locomotory behavior;GO:0001756 somitogenesis;GO:0007519 skeletal muscle tissue development;GO:0030036 actin cytoskeleton organization",
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        "protein_name": "Exonuclease mut-7 homolog isoform X1",
        "gene_name": "exd3",
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        "refseq_name": "exonuclease mut-7 homolog isoform X1",
        "refseq_ac": [
            {
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        "protein_names_refseq": "exonuclease mut-7 homolog isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_003199355.2. COMPLETENESS: full length., [RefSeq]",
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        ],
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        "length": 371,
        "protein_name": "Interferon-induced 35 kDa protein",
        "gene_name": "ifi35",
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        "protein_names_uniprotkb": "Interferon-induced 35 kDa protein",
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        "predicted_glycosites": 0,
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        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC137488811",
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        "refseq_name": "uncharacterized protein isoform X1",
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        "gene_names_uniprotkb": "LOC137488811",
        "gene_names_refseq": "LOC137488811",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005156263.1. COMPLETENESS: full length., [RefSeq]; Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. involved in DNA damage response in somatic cells: binds to acetylated histones and promotes degradation of histones., [UniProtKB, UniProtKB, UniProtKB]",
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        "ec_number_list": [],
        "go_molecular_function": "GO:0016504 peptidase activator activity;GO:0070628 proteasome binding",
        "go_cellular_component": "GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0000502 proteasome complex",
        "go_biological_process": "GO:0006281 DNA repair",
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        "hit_score": 0.3,
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        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AA53EEV4-1",
        "uniprot_id": [
            {
                "id": "A0AA53EEV4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA53EEV4",
                "type": "external"
            }
        ],
        "mass": 62679.0,
        "length": 543,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC137487208; zgc:172075",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005166693",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166693",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC137487208; zgc:172075; zgc:172075",
        "gene_names_refseq": "zgc:172075",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:137487208)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005166693.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "ec_number_list": [],
        "go_molecular_function": "GO:0005525 GTP binding",
        "go_cellular_component": "",
        "go_biological_process": "",
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        "record_id": "A0AA53EEV4-1",
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        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0AA52Z2I8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA52Z2I8",
                "type": "external"
            }
        ],
        "mass": 96085.0,
        "length": 846,
        "protein_name": "Protein bicaudal D homolog 2 isoform X1",
        "gene_name": "bicd2b",
        "organism": "Zebrafish",
        "refseq_name": "protein bicaudal D homolog 2 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005155947",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155947",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "bicd2b; bicd2",
        "gene_names_refseq": "bicd2",
        "protein_names_uniprotkb": "Protein bicaudal D homolog 2 isoform X1",
        "protein_names_refseq": "protein bicaudal D homolog 2 isoform X1",
        "tax_id": 7955,
        "disease": "spinal muscular atrophy with lower extremity predominant 2A (Disease Ontology:DOID:0070349); spinal muscular atrophy with lower extremity predominant 2B (Disease Ontology:DOID:0070350)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005155947.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0008093 cytoskeletal anchor activity;GO:0070840 dynein complex binding",
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        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A8M3ARZ7_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M3ARZ7",
                "type": "external"
            }
        ],
        "mass": 49398.0,
        "length": 425,
        "protein_name": "Galactosylceramide sulfotransferase isoform X1",
        "gene_name": "gal3st1a",
        "organism": "Zebrafish",
        "refseq_name": "galactosylceramide sulfotransferase",
        "refseq_ac": [
            {
                "id": "NP_001119924",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119924",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "gal3st1a; gal3st1; si:dkeyp-86g2.2",
        "gene_names_refseq": "gal3st1a; gal3st1; si:dkeyp-86g2.2",
        "protein_names_uniprotkb": "Galactosylceramide sulfotransferase isoform X1",
        "protein_names_refseq": "galactose-3-O-sulfotransferase 1; galactosylceramide sulfotransferase",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:793735);  (R-DRE-9840309)",
        "pathway_count": 2,
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        "publication_id_list": "26469318;27189481",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01011141.1, GDQH01031133.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476736, SAMEA4476737 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000005.1. On Jun 25, 2025 this sequence version replaced NP_001119924.1., [RefSeq]",
        "predicted_glycosites": 0,
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                "id": "2.8.2.11",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.2.11",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0001733 galactosylceramide sulfotransferase activity",
        "go_cellular_component": "GO:0000139 Golgi membrane",
        "go_biological_process": "GO:0042552 myelination;GO:0006682 galactosylceramide biosynthetic process",
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        "kg_view_protein": true
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    {
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        "uniprot_id": [
            {
                "id": "A0AA53EGP4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA53EGP4",
                "type": "external"
            }
        ],
        "mass": 241129.0,
        "length": 2267,
        "protein_name": "Nuclear receptor coactivator 6 isoform X1",
        "gene_name": "ncoa6",
        "organism": "Zebrafish",
        "refseq_name": "nuclear receptor coactivator 6 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005170622",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170622",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ncoa6",
        "gene_names_refseq": "ncoa6",
        "protein_names_uniprotkb": "Nuclear receptor coactivator 6 isoform X1",
        "protein_names_refseq": "nuclear receptor coactivator 6 isoform X1",
        "tax_id": 7955,
        "disease": "dilated cardiomyopathy (Disease Ontology:DOID:12930); lung cancer (Disease Ontology:DOID:1324); breast cancer (Disease Ontology:DOID:1612); colon cancer (Disease Ontology:DOID:219)",
        "pathway": " (dre:100144559)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005170622.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 5,
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        "predicted_o_glycosites": 5,
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        "missing_score": 10000,
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        "ec_number_list": [],
        "go_molecular_function": "GO:0003713 transcription coactivator activity",
        "go_cellular_component": "GO:0005634 nucleus",
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AA53EGP4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000011.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
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    {
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        "uniprot_id": [
            {
                "id": "A0A8M2BC75_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M2BC75",
                "type": "external"
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        ],
        "mass": 65839.0,
        "length": 599,
        "protein_name": "Apoptosis-inducing factor 3 isoform X1",
        "gene_name": "aifm3",
        "organism": "Zebrafish",
        "refseq_name": "apoptosis-inducing factor 3",
        "refseq_ac": [
            {
                "id": "NP_001121885",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121885",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "aifm3",
        "gene_names_refseq": "aifm3",
        "protein_names_uniprotkb": "Apoptosis-inducing factor 3 isoform X1",
        "protein_names_refseq": "apoptosis inducing factor, mitochondria associated 3; apoptosis-inducing factor 3; apoptosis-inducing factor, mitochondrion-associated, 3",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100150876)",
        "pathway_count": 1,
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        "publication_id_list": "26137170;28121514;28252024;37794116",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination        :: GFIL01016132.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000005.1. On Jun 7, 2025 this sequence version replaced NP_001121885.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
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        "missing_score": 10000,
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        "secondary_ac_list": "A0AC58JH06",
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        "go_molecular_function": "GO:0046872 metal ion binding;GO:0051537 2 iron, 2 sulfur cluster binding;GO:0016491 oxidoreductase activity;GO:0016651 oxidoreductase activity, acting on NAD(P)H",
        "go_cellular_component": "GO:0005739 mitochondrion",
        "go_biological_process": "GO:0072114 pronephros morphogenesis;GO:0097194 execution phase of apoptosis",
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            {
                "id": "A0AB32T4D5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32T4D5",
                "type": "external"
            }
        ],
        "mass": 61904.0,
        "length": 557,
        "protein_name": "Adenosine deaminase domain-containing protein 1",
        "gene_name": "adad1",
        "organism": "Zebrafish",
        "refseq_name": "adenosine deaminase domain-containing protein 1",
        "refseq_ac": [
            {
                "id": "NP_001277142",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001277142",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "adad1; fi42e08; wu:fi42e08",
        "gene_names_refseq": "adad1; fi42e08; wu:fi42e08",
        "protein_names_uniprotkb": "Adenosine deaminase domain-containing protein 1",
        "protein_names_refseq": "adenosine deaminase domain-containing protein 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:564818)",
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        "publication_count": 3,
        "publication_id_list": "25434820;27189481;37552671",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588732.31964734.1, SRR32588717.45766869.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN18715719, SAMN18715720 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Jun 25, 2025 this sequence version replaced NP_001277142.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]; The RNA-binding protein Adad1 is necessary for germ cell maintenance and meiosis in zebrafish. Publication Status: Online-Only, [RefSeq, PubMed]",
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        "go_molecular_function": "GO:0008251 tRNA-specific adenosine deaminase activity;GO:0003725 double-stranded RNA binding;GO:0003726 double-stranded RNA adenosine deaminase activity",
        "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006396 RNA processing;GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0036098 male germ-line stem cell population maintenance;GO:0006382 adenosine to inosine editing",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AC58JVE2-1",
        "uniprot_id": [
            {
                "id": "A0AC58JVE2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AC58JVE2",
                "type": "external"
            }
        ],
        "mass": 528661.0,
        "length": 4831,
        "protein_name": "E3 ubiquitin-protein ligase HERC2",
        "gene_name": "herc2",
        "organism": "Zebrafish",
        "refseq_name": "E3 ubiquitin-protein ligase HERC2 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_073810441",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073810441",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "herc2",
        "gene_names_refseq": "herc2",
        "protein_names_uniprotkb": "E3 ubiquitin-protein ligase HERC2; 2.3.2.26; HECT domain and RCC1-like domain-containing protein 2; HECT-type E3 ubiquitin transferase HERC2",
        "protein_names_refseq": "E3 ubiquitin-protein ligase HERC2 isoform X1",
        "tax_id": 7955,
        "disease": "autosomal recessive intellectual developmental disorder 38 (Disease Ontology:DOID:0081203); pigmentation disease (Disease Ontology:DOID:10123)",
        "pathway": " (dre:558479)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; E3 ubiquitin-protein ligase that regulates ubiquitin-dependent retention of repair proteins on damaged chromosomes. Recruited to sites of DNA damage in response to ionizing radiation (IR) and facilitates the assembly of UBE2N and RNF8 promoting DNA damage-induced formation of 'Lys-63'-linked ubiquitin chains. Acts as a mediator of binding specificity between UBE2N and RNF8. Involved in the maintenance of RNF168 levels. E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of XPA which influences the circadian oscillation of DNA excision repair activity. By controlling the steady-state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway. Also modulates iron metabolism by regulating the basal turnover of FBXL5., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005814 centriole",
        "go_biological_process": "GO:0006281 DNA repair;GO:0016567 protein ubiquitination",
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        "record_type": "protein",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AA54CQH7-1",
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            {
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        ],
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        "protein_name": "Histone H2A",
        "gene_name": "si:ch211-113a14.25",
        "organism": "Zebrafish",
        "refseq_name": "histone H2A-like",
        "refseq_ac": [
            {
                "id": "XP_073799542",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073799542",
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            }
        ],
        "gene_names_uniprotkb": "si:ch211-113a14.25; LOC100148591; si:ch211-113a14.29",
        "gene_names_refseq": "si:ch211-113a14.29",
        "protein_names_uniprotkb": "Histone H2A",
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        "pathway": " (dre:100148591);  (dre:561187);  (dre:563177);  (dre:570115);  (R-DRE-110330);  (R-DRE-110331);  (R-DRE-201722);  (R-DRE-212300);  (R-DRE-2299718);  (R-DRE-2559580);  (R-DRE-2559582);  (R-DRE-3214815);  (R-DRE-3214858);  (R-DRE-427359);  (R-DRE-427413);  (R-DRE-5250924);  (R-DRE-5625886);  (R-DRE-5689603);  (R-DRE-5689880);  (R-DRE-5689901);  (R-DRE-68616);  (R-DRE-73728);  (R-DRE-73772);  (R-DRE-8936459);  (R-DRE-9018519);  (R-DRE-9764725);  (R-DRE-9841922);  (R-DRE-9843940);  (R-DRE-9843970);  (R-DRE-9909649);  (R-DRE-9940951);  (R-DRE-9943411);  (R-DRE-9943962)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "secondary_ac_list": "A0AC58IZB6",
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        "go_molecular_function": "GO:0003677 DNA binding;GO:0046982 protein heterodimerization activity;GO:0030527 structural constituent of chromatin;GO:0140912 membrane destabilizing activity",
        "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0000786 nucleosome",
        "go_biological_process": "GO:0045087 innate immune response;GO:0050830 defense response to Gram-positive bacterium;GO:0031507 heterochromatin formation",
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        "filter_code": "0000000.0000001.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AC58JVK9-1",
        "uniprot_id": [
            {
                "id": "A0AC58JVK9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AC58JVK9",
                "type": "external"
            }
        ],
        "mass": 44481.0,
        "length": 393,
        "protein_name": "CaM kinase-like vesicle-associated protein",
        "gene_name": "camkva",
        "organism": "Zebrafish",
        "refseq_name": "caM kinase-like vesicle-associated protein isoform X1",
        "refseq_ac": [
            {
                "id": "XP_073810527",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073810527",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "camkva",
        "gene_names_refseq": "camkva",
        "protein_names_uniprotkb": "CaM kinase-like vesicle-associated protein",
        "protein_names_refseq": "caM kinase-like vesicle-associated protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Does not appear to have detectable kinase activity., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0004683 calcium/calmodulin-dependent protein kinase activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0045202 synapse;GO:0030659 cytoplasmic vesicle membrane",
        "go_biological_process": "GO:0007165 signal transduction",
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        "kg_view_protein": true
    },
    {
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        "uniprot_id": [
            {
                "id": "A0A8M3AYA1_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M3AYA1",
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        ],
        "mass": 272480.0,
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        "protein_name": "Filamin-A isoform X1",
        "gene_name": "flna",
        "organism": "Zebrafish",
        "refseq_name": "filamin-A isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009295045",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009295045",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "flna",
        "gene_names_refseq": "flna",
        "protein_names_uniprotkb": "Filamin-A isoform X1",
        "protein_names_refseq": "filamin-A isoform X1",
        "tax_id": 7955,
        "disease": "periventricular nodular heterotopia (Disease Ontology:DOID:0050454); myofibrillar myopathy 5 (Disease Ontology:DOID:0080096); X-linked chronic idiopathic intestinal pseudo-obstruction (Disease Ontology:DOID:0080681); distal myopathy 4 (Disease Ontology:DOID:0111190); X-linked cardiac valvular dysplasia (Disease Ontology:DOID:0111765); otopalatodigital syndrome spectrum disorder (Disease Ontology:DOID:0111782); otopalatodigital syndrome type 1 (Disease Ontology:DOID:0111783); otopalatodigital syndrome type 2 (Disease Ontology:DOID:0111784); frontometaphyseal dysplasia 1 (Disease Ontology:DOID:0111786); Melnick-Needles syndrome (Disease Ontology:DOID:0111788); terminal osseous dysplasia (Disease Ontology:DOID:0112149); tuberous sclerosis (Disease Ontology:DOID:13515); thoracic aortic aneurysm (Disease Ontology:DOID:14004); epilepsy (Disease Ontology:DOID:1826); osteochondrodysplasia (Disease Ontology:DOID:2256); craniosynostosis (Disease Ontology:DOID:2340); myopathy (Disease Ontology:DOID:423); mitral valve prolapse (Disease Ontology:DOID:988)",
        "pathway": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009295045.2. COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0051015 actin filament binding",
        "go_cellular_component": "GO:0005856 cytoskeleton",
        "go_biological_process": "GO:0030432 peristalsis;GO:0007399 nervous system development;GO:0030036 actin cytoskeleton organization;GO:0048565 digestive tract development;GO:0061371 determination of heart left/right asymmetry",
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        "kg_view_protein": true
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    {
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        ],
        "mass": 174854.0,
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        "protein_name": "CAP-Gly domain-containing linker protein 1 isoform X1",
        "gene_name": "clip1a",
        "organism": "Zebrafish",
        "refseq_name": "CAP-Gly domain-containing linker protein 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009300267",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009300267",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "clip1a",
        "gene_names_refseq": "clip1a",
        "protein_names_uniprotkb": "CAP-Gly domain-containing linker protein 1 isoform X1",
        "protein_names_refseq": "CAP-Gly domain-containing linker protein 1 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009300267.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 2,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 2,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 2,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005874 microtubule",
        "go_biological_process": "GO:0031116 positive regulation of microtubule polymerization",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AA54CQ70-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AB32TBS6-1",
        "uniprot_id": [
            {
                "id": "A0AB32TBS6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AB32TBS6",
                "type": "external"
            }
        ],
        "mass": 86441.0,
        "length": 812,
        "protein_name": "Transducin-like enhancer protein 2a isoform X1",
        "gene_name": "tle2a",
        "organism": "Zebrafish",
        "refseq_name": "transducin-like enhancer protein 2a isoform X1",
        "refseq_ac": [
            {
                "id": "XP_068072439",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072439",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tle2a; fc18h03; sb:eu1034; sb:eu408; si:ch211-81i17.1; tle2; wu:fb96a10; wu:fc18h03",
        "gene_names_refseq": "fc18h03; sb:eu1034; sb:eu408; si:ch211-81i17.1; tle2a; tle2; wu:fb96a10; wu:fc18h03",
        "protein_names_uniprotkb": "Transducin-like enhancer protein 2a isoform X1",
        "protein_names_refseq": "transducin-like enhancer protein 2a isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068072439.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006355 regulation of DNA-templated transcription",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AB32TBS6-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M2BF37-1",
        "uniprot_id": [
            {
                "id": "A0A8M2BF37_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M2BF37",
                "type": "external"
            }
        ],
        "mass": 121793.0,
        "length": 1104,
        "protein_name": "Leucine-rich repeat flightless-interacting protein 1 isoform X1",
        "gene_name": "lrrfip1a",
        "organism": "Zebrafish",
        "refseq_name": "leucine-rich repeat flightless-interacting protein 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005167696",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167696",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "lrrfip1a",
        "gene_names_refseq": "lrrfip1a",
        "protein_names_uniprotkb": "Leucine-rich repeat flightless-interacting protein 1 isoform X1",
        "protein_names_refseq": "leucine-rich repeat flightless-interacting protein 1 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005167696.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "GO:0006355 regulation of DNA-templated transcription",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M2BF37-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9PKH4-1",
        "uniprot_id": [
            {
                "id": "A0A8M9PKH4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9PKH4",
                "type": "external"
            }
        ],
        "mass": 46810.0,
        "length": 412,
        "protein_name": "Sphingomyelin synthase-related protein 1",
        "gene_name": "samd8a; samd8",
        "organism": "Zebrafish",
        "refseq_name": "sphingomyelin synthase-related protein 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_021322761",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322761",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "samd8a; samd8; samd8; zgc:162183",
        "gene_names_refseq": "samd8; zgc:162183",
        "protein_names_uniprotkb": "Sphingomyelin synthase-related protein 1; 3.1.4.62; Ceramide phosphoethanolamine synthase; Phosphatidylethanolamine Phospholipase C; Sterile alpha motif domain-containing protein 8",
        "protein_names_refseq": "sphingomyelin synthase-related protein 1 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322761.1. COMPLETENESS: full length., [RefSeq]; Has phospholipase C (PLC) activity. Shows specificity for phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE), hydrolyzing PE to produce phosphoethanolamine and diacylglycerol (1,2-diacyl-sn-glycerol, DAG). This reaction might act as a regulatory switch to activate serine palmitoyltransferase (SPT) and promote sphingolipid metabolism. Can also function as a ceramide phosphoethanolamine (N-acylsphingoid 1-phosphoethanolamine, CPE) synthase when intracellular ceramide levels are elevated. Binds the headgroup from PE, which is smaller and more hydrophilic than the phosphocholine headgroup transferred in the canonical sphingomyelin synthesis (SMS) reaction by SMS1 or SMS2, and transfers it on to the primary hydroxyl of a ceramide in the lumen of the endoplasmic reticulum. Plays a role as a ceramide sensor, helping to regulate ceramide homeostasis in the endoplasmic reticulum, which is critical for maintaining the integrity of the early secretory pathway., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "2.7.8.27",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.27",
                "type": "external"
            },
            {
                "id": "3.1.4.62",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.62",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0016780 phosphotransferase activity, for other substituted phosphate groups",
        "go_cellular_component": "GO:0016020 membrane",
        "go_biological_process": "GO:0046513 ceramide biosynthetic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M9PKH4-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9Q7I3-1",
        "uniprot_id": [
            {
                "id": "A0A8M9Q7I3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9Q7I3",
                "type": "external"
            }
        ],
        "mass": 309703.0,
        "length": 2821,
        "protein_name": "Interphotoreceptor matrix proteoglycan 2",
        "gene_name": "impg2b",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein impg2b isoform X1",
        "refseq_ac": [
            {
                "id": "XP_021329195",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329195",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "impg2b",
        "gene_names_refseq": "impg2b",
        "protein_names_uniprotkb": "Interphotoreceptor matrix proteoglycan 2; Sialoprotein associated with cones and rods proteoglycan",
        "protein_names_refseq": "uncharacterized protein impg2b isoform X1",
        "tax_id": 7955,
        "disease": "vitelliform macular dystrophy (Disease Ontology:DOID:0050661); retinitis pigmentosa 56 (Disease Ontology:DOID:0110371)",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021329195.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 2,
        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0008201 heparin binding",
        "go_cellular_component": "GO:0033165 interphotoreceptor matrix",
        "go_biological_process": "GO:0007601 visual perception",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M9Q7I3-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.001000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M3B2M3-1",
        "uniprot_id": [
            {
                "id": "A0A8M3B2M3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M3B2M3",
                "type": "external"
            }
        ],
        "mass": 58946.0,
        "length": 509,
        "protein_name": "Phosphodiesterase",
        "gene_name": "pde9aa",
        "organism": "Zebrafish",
        "refseq_name": "high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009302928",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302928",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pde9aa",
        "gene_names_refseq": "pde9aa",
        "protein_names_uniprotkb": "Phosphodiesterase; 3.1.4.-",
        "protein_names_refseq": "high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1",
        "tax_id": 7955,
        "disease": "Huntington's disease (Disease Ontology:DOID:12858); dilated cardiomyopathy (Disease Ontology:DOID:12930); congestive heart failure (Disease Ontology:DOID:6000)",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009302928.1. COMPLETENESS: full length., [RefSeq]; Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP. Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart. Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein. In brain, involved in cognitive function, such as learning and long-term memory., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "protein_name": "Probable ribonuclease ZC3H12B isoform X1",
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        "refseq_name": "probable ribonuclease ZC3H12B isoform X1",
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                "id": "XP_021332114",
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        "protein_name": "Dermatan-sulfate epimerase isoform X1",
        "gene_name": "dse",
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        "refseq_name": "dermatan-sulfate epimerase precursor",
        "refseq_ac": [
            {
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        "gene_names_refseq": "dse; si:dkey-121j17.2",
        "protein_names_uniprotkb": "Dermatan-sulfate epimerase isoform X1",
        "protein_names_refseq": "dermatan-sulfate epimerase precursor",
        "tax_id": 7955,
        "disease": "Ehlers-Danlos syndrome musculocontractural type 2 (Disease Ontology:DOID:0080737)",
        "pathway": " (dre:568713);  (R-DRE-2022923)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01023241.1, SRR32588717.29810811.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505382, SAMEA3505392 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000020.1. On Jun 25, 2025 this sequence version replaced NP_001025396.1., [RefSeq]",
        "predicted_glycosites": 1,
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A8M2BG52",
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        "mass": 36659.0,
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        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "si:ch211-107o10.3",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005168926",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168926",
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        ],
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        "gene_names_refseq": "fd55e03; si:ch211-107o10.3; wu:fd55e03",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "Leber congenital amaurosis (Disease Ontology:DOID:14791)",
        "pathway": " (dre:407663)",
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        "publication_id_list": "22205629;26469318;28252024",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005168926.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0016491 oxidoreductase activity",
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    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A8M1N8D3",
                "type": "external"
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        ],
        "mass": 44413.0,
        "length": 403,
        "protein_name": "Prostaglandin E2 receptor EP4 subtype",
        "gene_name": "ptger4a",
        "organism": "Zebrafish",
        "refseq_name": "prostaglandin E receptor 4 (subtype EP4) a",
        "refseq_ac": [
            {
                "id": "NP_001034718",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034718",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "ptger4a; ptger4l; ptger4",
        "gene_names_refseq": "ptger4a; ptger4l; ptger4",
        "protein_names_uniprotkb": "Prostaglandin E2 receptor EP4 subtype; Prostanoid EP4 receptor",
        "protein_names_refseq": "PRS4; ep4a; ep4; prostaglandin E receptor 4 (subtype EP4) a",
        "tax_id": 7955,
        "disease": "aspirin-induced respiratory disease (Disease Ontology:DOID:0080822); osteoporosis (Disease Ontology:DOID:11476); retinal ischemia (Disease Ontology:DOID:12510); dilated cardiomyopathy (Disease Ontology:DOID:12930); cystitis (Disease Ontology:DOID:1679); transient cerebral ischemia (Disease Ontology:DOID:224); arteriosclerosis (Disease Ontology:DOID:2349); acute kidney failure (Disease Ontology:DOID:3021); aortic aneurysm (Disease Ontology:DOID:3627); ankylosing spondylitis (Disease Ontology:DOID:7147); end stage renal disease (Disease Ontology:DOID:783); myocarditis (Disease Ontology:DOID:820); ulcerative colitis (Disease Ontology:DOID:8577)",
        "pathway": " (dre:562469)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "16391234;17579056;17581586;18486942;23770421;32080283;34181931;34252451;35924455;36645741",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC127559.1, DQ202321.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On Jun 25, 2025 this sequence version replaced NP_001034718.2. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; ADAMTS1 is regulated by the EP4 receptor in the zebrafish ovary., [RefSeq, PubMed]; Ep4a, a PGE2 receptor isoform of EP4, is involved in lymphoid precursor development in zebrafish., [RefSeq, PubMed]; Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function., [UniProtKB, UniProtKB, UniProtKB]",
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 13,
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "GO:0004957 prostaglandin E receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:1990402 embryonic liver development;GO:0033993 response to lipid;GO:0042074 cell migration involved in gastrulation;GO:0002244 hematopoietic progenitor cell differentiation;GO:0033077 T cell differentiation in thymus",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
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        "record_type": "protein",
        "filter_code": "0000000.0000111.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AA53ECJ5-1",
        "uniprot_id": [
            {
                "id": "A0AA53ECJ5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA53ECJ5",
                "type": "external"
            }
        ],
        "mass": 60966.0,
        "length": 543,
        "protein_name": "Flavin-containing monooxygenase",
        "gene_name": "si:dkey-239i20.4",
        "organism": "Zebrafish",
        "refseq_name": "si:dkey-239i20.4 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005160478",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005160478",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:dkey-239i20.4; fc14c11; wu:fc14c11; zgc:153645",
        "gene_names_refseq": "fc14c11; si:dkey-239i20.4; wu:fc14c11; zgc:153645",
        "protein_names_uniprotkb": "Flavin-containing monooxygenase; 1.-.-.-",
        "protein_names_refseq": "si:dkey-239i20.4 isoform X1",
        "tax_id": 7955,
        "disease": "trimethylaminuria (Disease Ontology:DOID:0080361); hypertension (Disease Ontology:DOID:10763); inherited metabolic disorder (Disease Ontology:DOID:655)",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005160478.1. COMPLETENESS: full length., [RefSeq]; Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics. Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes. In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
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        "total_o_glycosites": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 3,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "1.-.-.-",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0034899 trimethylamine monooxygenase activity;GO:0050661 NADP binding;GO:0004499 N,N-dimethylaniline monooxygenase activity",
        "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AA53ECJ5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M3AQH5-1",
        "uniprot_id": [
            {
                "id": "A0A8M3AQH5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M3AQH5",
                "type": "external"
            }
        ],
        "mass": 113141.0,
        "length": 1030,
        "protein_name": "Myocardin-related transcription factor A isoform X1",
        "gene_name": "mrtfaa",
        "organism": "Zebrafish",
        "refseq_name": "myocardin-related transcription factor A isoform X1",
        "refseq_ac": [
            {
                "id": "XP_073800520",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073800520",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mrtfaa",
        "gene_names_refseq": "mrtfaa",
        "protein_names_uniprotkb": "Myocardin-related transcription factor A isoform X1",
        "protein_names_refseq": "myocardin-related transcription factor A isoform X1",
        "tax_id": 7955,
        "disease": "immunodeficiency 66 (Disease Ontology:DOID:0111998); Alzheimer's disease (Disease Ontology:DOID:10652); transient cerebral ischemia (Disease Ontology:DOID:224); acute megakaryocytic leukemia (Disease Ontology:DOID:8761)",
        "pathway": "",
        "pathway_count": 0,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 2,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 2,
        "predicted_c_glycosites": 0,
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        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 4,
        "glyco_site_count": 2,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0AC58J207;A0AC58J212;A0AC58J215;A0AC58J218;A0AC58J228;A0AC58J232",
        "ec_number_list": [],
        "go_molecular_function": "GO:0003713 transcription coactivator activity",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M3AQH5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AA70QQ18-1",
        "uniprot_id": [
            {
                "id": "A0AA70QQ18_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA70QQ18",
                "type": "external"
            }
        ],
        "mass": 47831.0,
        "length": 422,
        "protein_name": "Magnesium transporter",
        "gene_name": "mrs2",
        "organism": "Zebrafish",
        "refseq_name": "magnesium transporter MRS2 homolog, mitochondrial isoform X1",
        "refseq_ac": [
            {
                "id": "XP_693621",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693621",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mrs2",
        "gene_names_refseq": "mrs2",
        "protein_names_uniprotkb": "Magnesium transporter",
        "protein_names_refseq": "magnesium transporter MRS2 homolog, mitochondrial isoform X1",
        "tax_id": 7955,
        "disease": "",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_693621.5. COMPLETENESS: full length., [RefSeq]; Magnesium transporter that mediates the influx of magnesium into the mitochondrial matrix and regulates magnesium metabolism. Also permeable to calcium, sodium and potassium ions. Required for normal expression of the mitochondrial respiratory complex I subunits. May play a role in maintaining the inner mitochondrial membrane potential., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
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        "go_molecular_function": "",
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        "go_biological_process": "",
        "synthesized_glycan_count": 0,
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        "record_id": "A0AA70QQ18-1",
        "record_type": "protein",
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        "kg_view_protein": true
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    {
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        "uniprot_id": [
            {
                "id": "A0AA54FLJ5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA54FLJ5",
                "type": "external"
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        ],
        "mass": 72989.0,
        "length": 639,
        "protein_name": "Serine/threonine-protein kinase Nek11",
        "gene_name": "nek11",
        "organism": "Zebrafish",
        "refseq_name": "serine/threonine-protein kinase Nek11 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009290854",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290854",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "nek11",
        "gene_names_refseq": "nek11",
        "protein_names_uniprotkb": "Serine/threonine-protein kinase Nek11; 2.7.11.1; Never in mitosis A-related kinase 11",
        "protein_names_refseq": "serine/threonine-protein kinase Nek11 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009290854.1. COMPLETENESS: full length., [RefSeq]; Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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                "id": "2.7.11.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
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            {
                "id": "2.7.11.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13",
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            {
                "id": "2.7.11.25",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25",
                "type": "external"
            },
            {
                "id": "2.7.10.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1",
                "type": "external"
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            {
                "id": "2.7.11.22",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22",
                "type": "external"
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            {
                "id": "2.7.11.21",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21",
                "type": "external"
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                "id": "2.7.11.17",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17",
                "type": "external"
            },
            {
                "id": "2.7.12.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1",
                "type": "external"
            },
            {
                "id": "2.7.12.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2",
                "type": "external"
            },
            {
                "id": "2.7.11.24",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24",
                "type": "external"
            },
            {
                "id": "2.7.10.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2",
                "type": "external"
            },
            {
                "id": "2.7.11.23",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23",
                "type": "external"
            },
            {
                "id": "2.7.1.150",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150",
                "type": "external"
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            {
                "id": "2.7.11.12",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12",
                "type": "external"
            },
            {
                "id": "2.7.11.39",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39",
                "type": "external"
            },
            {
                "id": "2.7.11.11",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11",
                "type": "external"
            },
            {
                "id": "2.7.1.153",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153",
                "type": "external"
            },
            {
                "id": "2.7.1.137",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137",
                "type": "external"
            },
            {
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154",
                "type": "external"
            },
            {
                "id": "2.7.11.26",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26",
                "type": "external"
            },
            {
                "id": "2.7.11.31",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31",
                "type": "external"
            }
        ],
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        "kg_view_protein": true
    },
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        ],
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        "protein_name": "CUB and zona pellucida-like domain-containing protein 1 isoform X1",
        "gene_name": "LOC110437703",
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        "gene_names_uniprotkb": "LOC110437703",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "CUB and zona pellucida-like domain-containing protein 1 isoform X1",
        "protein_names_refseq": "",
        "tax_id": 7955,
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            {
                "id": "XP_005161978",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161978",
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        "gene_names_uniprotkb": "vgll4a",
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        "protein_names_uniprotkb": "Transcription cofactor vestigial-like protein 4 isoform X1",
        "protein_names_refseq": "transcription cofactor vestigial-like protein 4 isoform X1",
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    {
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        ],
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        "length": 2253,
        "protein_name": "Histone-lysine N-methyltransferase SETD1A isoform X1",
        "gene_name": "setd1a",
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        "refseq_name": "histone-lysine N-methyltransferase SETD1A isoform X1",
        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329647",
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        "protein_names_uniprotkb": "Histone-lysine N-methyltransferase SETD1A isoform X1",
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        ],
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        "protein_name": "Small subunit processome component 20 homolog isoform X1",
        "gene_name": "utp20",
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        "refseq_name": "small subunit processome component 20 homolog isoform X1",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009298288",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "utp20",
        "gene_names_refseq": "utp20",
        "protein_names_uniprotkb": "Small subunit processome component 20 homolog isoform X1",
        "protein_names_refseq": "small subunit processome component 20 homolog isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009298288.1. COMPLETENESS: full length., [RefSeq]",
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        "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AA53EB82-1",
        "uniprot_id": [
            {
                "id": "A0AA53EB82_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA53EB82",
                "type": "external"
            }
        ],
        "mass": 112922.0,
        "length": 1005,
        "protein_name": "Ephrin type-A receptor 6",
        "gene_name": "epha6",
        "organism": "Zebrafish",
        "refseq_name": "ephrin type-A receptor 6 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005159987",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005159987",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "epha6",
        "gene_names_refseq": "epha6",
        "protein_names_uniprotkb": "Ephrin type-A receptor 6; 2.7.10.1; EPH homology kinase 2",
        "protein_names_refseq": "ephrin type-A receptor 6 isoform X1",
        "tax_id": 7955,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005159987.1. COMPLETENESS: full length., [RefSeq]; Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling., [UniProtKB, UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "2.7.10.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1",
                "type": "external"
            },
            {
                "id": "2.7.10.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2",
                "type": "external"
            },
            {
                "id": "2.7.11.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
                "type": "external"
            },
            {
                "id": "2.7.12.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1",
                "type": "external"
            },
            {
                "id": "2.7.12.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2",
                "type": "external"
            }
        ],
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        "synthesized_glycan_count": 0,
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        "record_id": "A0AA53EB82-1",
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        "filter_code": "0000000.0000000.010000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M9QFK8-1",
        "uniprot_id": [
            {
                "id": "A0A8M9QFK8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M9QFK8",
                "type": "external"
            }
        ],
        "mass": 56656.0,
        "length": 506,
        "protein_name": "receptor protein serine/threonine kinase",
        "gene_name": "acvr1l",
        "organism": "Zebrafish",
        "refseq_name": "activin receptor type-1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_021334426",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334426",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "acvr1l; acvr1; alk2; alk8sum; alk8; etID124543.2; fk50h05; laf; lost-a-fin; mfn; wu:fk50h05",
        "gene_names_refseq": "acvr1l; acvr1; alk2; alk8sum; alk8; etID124543.2; fk50h05; laf; lost-a-fin; mfn; wu:fk50h05",
        "protein_names_uniprotkb": "receptor protein serine/threonine kinase; 2.7.11.30",
        "protein_names_refseq": "activin receptor type-1 isoform X1",
        "tax_id": 7955,
        "disease": "primary open angle glaucoma (Disease Ontology:DOID:1070); severe pre-eclampsia (Disease Ontology:DOID:13129); fibrodysplasia ossificans progressiva (Disease Ontology:DOID:13374); exfoliation syndrome (Disease Ontology:DOID:13641); primary angle-closure glaucoma (Disease Ontology:DOID:1405); pancreatic cancer (Disease Ontology:DOID:1793)",
        "pathway": "",
        "pathway_count": 0,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021334426.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "2.7.11.30",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.30",
                "type": "external"
            }
        ],
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M9QFK8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AA52Z4K0-1",
        "uniprot_id": [
            {
                "id": "A0AA52Z4K0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA52Z4K0",
                "type": "external"
            }
        ],
        "mass": 191086.0,
        "length": 1715,
        "protein_name": "Methylcytosine dioxygenase TET",
        "gene_name": "tet2",
        "organism": "Zebrafish",
        "refseq_name": "tet methylcytosine dioxygenase 2",
        "refseq_ac": [
            {
                "id": "NP_001430370",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430370",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tet2",
        "gene_names_refseq": "im:7136741; si:ch211-216c6.1; tet2l; tet2",
        "protein_names_uniprotkb": "Methylcytosine dioxygenase TET; 1.14.11.80",
        "protein_names_refseq": "ten-eleven-translocation 2; tet methylcytosine dioxygenase 2",
        "tax_id": 7955,
        "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); myelodysplastic syndrome (Disease Ontology:DOID:0050908); colon adenoma (Disease Ontology:DOID:0050912); chronic myelomonocytic leukemia (Disease Ontology:DOID:0080188); stomach cancer (Disease Ontology:DOID:10534); breast cancer (Disease Ontology:DOID:1612); myeloproliferative neoplasm (Disease Ontology:DOID:2226); colon adenocarcinoma (Disease Ontology:DOID:234); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung non-small cell carcinoma (Disease Ontology:DOID:3908); primary immunodeficiency disease (Disease Ontology:DOID:612); hepatocellular carcinoma (Disease Ontology:DOID:684); acute myeloid leukemia (Disease Ontology:DOID:9119); colorectal cancer (Disease Ontology:DOID:9256); nasopharynx carcinoma (Disease Ontology:DOID:9261)",
        "pathway": "",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01001873.1, GFIL01021817.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505374 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Sep 15, 2025 this sequence version replaced XP_005159960.2. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 1,
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        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "1.14.11.80",
                "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.80",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0051213 dioxygenase activity",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
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        "record_id": "A0AA52Z4K0-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.010000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M2BLW2-1",
        "uniprot_id": [
            {
                "id": "A0A8M2BLW2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M2BLW2",
                "type": "external"
            }
        ],
        "mass": 47536.0,
        "length": 422,
        "protein_name": "Transcriptional enhancer factor TEF-1a isoform X1",
        "gene_name": "tead1a",
        "organism": "Zebrafish",
        "refseq_name": "transcriptional enhancer factor TEF-1a",
        "refseq_ac": [
            {
                "id": "NP_998012",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998012",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tead1a; tead1; zgc:63696",
        "gene_names_refseq": "tead1a; tead1; zgc:63696",
        "protein_names_uniprotkb": "Transcriptional enhancer factor TEF-1a isoform X1",
        "protein_names_refseq": "TEA domain family member 1; transcriptional enhancer factor TEF-1a",
        "tax_id": 7955,
        "disease": "Sveinsson chorioretinal atrophy (Disease Ontology:DOID:0111228)",
        "pathway": "",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588733.781163.1, SRR32588723.195120.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476732, SAMEA4476739 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On or before Jul 28, 2025 this sequence version replaced XP_005174371.2, NP_998012.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "synthesized_glycan_count": 0,
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        "record_id": "A0A8M2BLW2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M3AS99-1",
        "uniprot_id": [
            {
                "id": "A0A8M3AS99_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M3AS99",
                "type": "external"
            }
        ],
        "mass": 37788.0,
        "length": 340,
        "protein_name": "Annexin",
        "gene_name": "anxa1a",
        "organism": "Zebrafish",
        "refseq_name": "annexin A1a isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009299724",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009299724",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "anxa1a; anx1a; anxa1; wu:fa01d11; wu:fa05d11; wu:fk69h01",
        "gene_names_refseq": "anx1a; anxa1a; anxa1; wu:fa01d11; wu:fa05d11; wu:fk69h01",
        "protein_names_uniprotkb": "Annexin",
        "protein_names_refseq": "annexin A1a isoform X1",
        "tax_id": 7955,
        "disease": "ductal carcinoma in situ (Disease Ontology:DOID:0060074); colitis (Disease Ontology:DOID:0060180); dry eye syndrome (Disease Ontology:DOID:10140); pleurisy (Disease Ontology:DOID:10247); stomach cancer (Disease Ontology:DOID:10534); hypertension (Disease Ontology:DOID:10763); uveitis (Disease Ontology:DOID:13141); paranasal sinus benign neoplasm (Disease Ontology:DOID:1350); hypothyroidism (Disease Ontology:DOID:1459); squamous cell carcinoma (Disease Ontology:DOID:1749); pancreatic cancer (Disease Ontology:DOID:1793); brain ischemia (Disease Ontology:DOID:2316); transitional cell carcinoma (Disease Ontology:DOID:2671); keratosis follicularis (Disease Ontology:DOID:2734); invasive ductal carcinoma (Disease Ontology:DOID:3008); acute kidney failure (Disease Ontology:DOID:3021); malignant astrocytoma (Disease Ontology:DOID:3069); ischemia (Disease Ontology:DOID:326); cerebral infarction (Disease Ontology:DOID:3526); pulmonary fibrosis (Disease Ontology:DOID:3770); renal cell carcinoma (Disease Ontology:DOID:4450); seborrheic keratosis (Disease Ontology:DOID:6498); hyperthyroidism (Disease Ontology:DOID:7998); cataract (Disease Ontology:DOID:83); psoriasis (Disease Ontology:DOID:8893)",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009299724.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 25,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
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        "protein_names_refseq": "solute carrier family 8 member 4a isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Homeobox protein PKNOX1.1 isoform X1",
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        "gene_names_refseq": "fc13f10; pknox1.1; prep1.1; prep1; wu:fc13f10",
        "protein_names_uniprotkb": "Homeobox protein PKNOX1.1 isoform X1",
        "protein_names_refseq": "homeobox protein PKNOX1.1",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC054667.1, AY052752.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000009.1. On Jun 25, 2025 this sequence version replaced NP_571966.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Analysis of the regulatory region of the zebrafish Prep1.1 gene and the promoter of human PREP1 Erratum:[PLoS One. 2011;6(4). doi:10.1371/annotation/6de90ec9-0314-40ec-b634-27373373aabc. Pezzinenti, Federica [corrected to Pezzimenti, Federica]] Publication Status: Online-Only, [RefSeq, PubMed]; Has a unique genetic function in craniofacial chondrogenesis and it plays an essential role in hindbrain development., [RefSeq, PubMed]",
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        "protein_name": "T-box transcription factor TBX5b isoform X1",
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            {
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        "tax_id": 7955,
        "disease": "Holt-Oram syndrome (Disease Ontology:DOID:0060468)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        ],
        "mass": 82987.0,
        "length": 742,
        "protein_name": "protein acetyllysine N-acetyltransferase",
        "gene_name": "sirt1",
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        "refseq_name": "NAD-dependent protein deacetylase sirtuin-1 isoform X1",
        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001334440",
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        "protein_names_uniprotkb": "protein acetyllysine N-acetyltransferase; 2.3.1.286",
        "protein_names_refseq": "NAD-dependent protein deacetylase sirtuin-1 isoform X1",
        "tax_id": 7955,
        "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); prostate cancer (Disease Ontology:DOID:10283); nephrogenic diabetes insipidus (Disease Ontology:DOID:12387); Huntington's disease (Disease Ontology:DOID:12858); epilepsy (Disease Ontology:DOID:1826); macular degeneration (Disease Ontology:DOID:4448); steatotic liver disease (Disease Ontology:DOID:9452); senile cataract (Disease Ontology:DOID:9669)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001334440.4. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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    {
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        "uniprot_id": [
            {
                "id": "A0AA52Z2T5_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA52Z2T5",
                "type": "external"
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        ],
        "mass": 34735.0,
        "length": 291,
        "protein_name": "Elongation of very long chain fatty acids protein 5",
        "gene_name": "elovl5",
        "organism": "Zebrafish",
        "refseq_name": "very long chain fatty acid elongase 5",
        "refseq_ac": [
            {
                "id": "NP_956747",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956747",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "elovl5; ELOVL5; zgc:63549",
        "gene_names_refseq": "elovl5; zgc:63549",
        "protein_names_uniprotkb": "Elongation of very long chain fatty acids protein 5; 2.3.1.199; 3-keto acyl-CoA synthase ELOVL5; ELOVL FA elongase 5; ELOVL fatty acid elongase 5; Very long chain 3-ketoacyl-CoA synthase 5; Very long chain 3-oxoacyl-CoA synthase 5",
        "protein_names_refseq": "ELOVL family member 5, elongation of long chain fatty acids; fatty acid elongase 5; very long chain fatty acid elongase 5",
        "tax_id": 7955,
        "disease": "spinocerebellar ataxia 38 (Disease Ontology:DOID:0050985)",
        "pathway": "",
        "pathway_count": 0,
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        "publication_id_list": "19025614;19615462;37080058",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588726.43129356.1, SRR32588714.43205579.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505392, SAMEA4476730 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On Jun 25, 2025 this sequence version replaced NP_956747.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators., [UniProtKB, HAMAP, UniProtKB]; Expression of elongase was significantly highest in pre-vitellogenic follicles, followed by maturation stage. Publication Status: Online-Only, [RefSeq, PubMed]; Hepatic transcriptome analysis reveals that elovl5 deletion promotes PUFA biosynthesis and deposition., [RefSeq, PubMed]; This study investigated the expression of genes encoding enzymes involved in long-chain polyunsaturated fatty acids biosynthesis, namely fatty acyl desaturase (Fad) and Elovl5- and Elovl2-like elongases, during early embryonic development of zebrafish., [RefSeq, PubMed]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "2.3.1.199",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.199",
                "type": "external"
            }
        ],
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        "record_id": "A0AA52Z2T5-1",
        "record_type": "protein",
        "filter_code": "0000000.0000110.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AA54CGF0-1",
        "uniprot_id": [
            {
                "id": "A0AA54CGF0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA54CGF0",
                "type": "external"
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        ],
        "mass": 66918.0,
        "length": 598,
        "protein_name": "Nuclear receptor subfamily 4 group A member 2",
        "gene_name": "nr4a2a",
        "organism": "Zebrafish",
        "refseq_name": "nuclear receptor subfamily 4 group A member 2a isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009302740",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302740",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "nr4a2a",
        "gene_names_refseq": "nr4a2a",
        "protein_names_uniprotkb": "Nuclear receptor subfamily 4 group A member 2",
        "protein_names_refseq": "nuclear receptor subfamily 4 group A member 2a isoform X1",
        "tax_id": 7955,
        "disease": "Parkinsonism (Disease Ontology:DOID:0080855); Parkinson's disease (Disease Ontology:DOID:14330); epilepsy (Disease Ontology:DOID:1826); schizophrenia (Disease Ontology:DOID:5419)",
        "pathway": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009302740.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
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        "reported_fully_resolved_glycans": 0,
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        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "glyco_site_count": 0,
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        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AA54CGF0-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M1QLI4-1",
        "uniprot_id": [
            {
                "id": "A0A8M1QLI4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M1QLI4",
                "type": "external"
            }
        ],
        "mass": 39266.0,
        "length": 345,
        "protein_name": "P2Y purinoceptor 12 isoform X1",
        "gene_name": "p2ry12",
        "organism": "Zebrafish",
        "refseq_name": "P2Y purinoceptor 12",
        "refseq_ac": [
            {
                "id": "NP_001429033",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429033",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "p2ry12",
        "gene_names_refseq": "p2ry12",
        "protein_names_uniprotkb": "P2Y purinoceptor 12 isoform X1",
        "protein_names_refseq": "P2Y purinoceptor 12; purinergic receptor P2Y, G-protein coupled, 12",
        "tax_id": 7955,
        "disease": "peripheral artery disease (Disease Ontology:DOID:0050830); platelet-type bleeding disorder 8 (Disease Ontology:DOID:0060692); thrombosis (Disease Ontology:DOID:0060903); asthma (Disease Ontology:DOID:2841); cerebrovascular disease (Disease Ontology:DOID:6713); abdominal aortic aneurysm (Disease Ontology:DOID:7693); systemic lupus erythematosus (Disease Ontology:DOID:9074); type 2 diabetes mellitus (Disease Ontology:DOID:9352)",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588717.27695307.1, SRR32588729.32455964.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505375, SAMEA3505383 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jul 28, 2025 this sequence version replaced XP_001921964.2. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "kg_view_protein": true
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    {
        "uniprot_canonical_ac": "A0A8M2B577-1",
        "uniprot_id": [
            {
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                "url": "https://www.uniprot.org/uniprot/A0A8M2B577",
                "type": "external"
            }
        ],
        "mass": 36502.0,
        "length": 334,
        "protein_name": "Cathepsin L.1 isoform X1",
        "gene_name": "ctsl.1",
        "organism": "Zebrafish",
        "refseq_name": "cathepsin L.1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005158834",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005158834",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ctsl.1; zgc:92089",
        "gene_names_refseq": "ctsl.1; zgc:92089",
        "protein_names_uniprotkb": "Cathepsin L.1 isoform X1",
        "protein_names_refseq": "cathepsin L.1 isoform X1",
        "tax_id": 7955,
        "disease": "COVID-19 (Disease Ontology:DOID:0080600); otitis media (Disease Ontology:DOID:10754); nephrotic syndrome (Disease Ontology:DOID:1184); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); alcohol use disorder (Disease Ontology:DOID:1574); brain ischemia (Disease Ontology:DOID:2316); pancreatitis (Disease Ontology:DOID:4989); hepatocellular carcinoma (Disease Ontology:DOID:684); muscular atrophy (Disease Ontology:DOID:767); hyperthyroidism (Disease Ontology:DOID:7998); type 2 diabetes mellitus (Disease Ontology:DOID:9352)",
        "pathway": "",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005158834.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "record_id": "A0A8M2B577-1",
        "record_type": "protein",
        "filter_code": "0000000.0000010.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M2BDL9-1",
        "uniprot_id": [
            {
                "id": "A0A8M2BDL9_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M2BDL9",
                "type": "external"
            }
        ],
        "mass": 75109.0,
        "length": 672,
        "protein_name": "Protein phosphatase 1 regulatory subunit 12C",
        "gene_name": "ppp1r12c",
        "organism": "Zebrafish",
        "refseq_name": "protein phosphatase 1 regulatory subunit 12C isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005166283",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166283",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ppp1r12c; fi37e03; mypt2; wu:fc07c03; wu:fi37e03; zgc:152881",
        "gene_names_refseq": "fi37e03; mypt2; ppp1r12c; wu:fc07c03; wu:fi37e03; zgc:152881",
        "protein_names_uniprotkb": "Protein phosphatase 1 regulatory subunit 12C; Protein phosphatase 1 myosin-binding subunit of 85 kDa",
        "protein_names_refseq": "protein phosphatase 1 regulatory subunit 12C isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005166283.1. COMPLETENESS: full length., [RefSeq]; Regulates myosin phosphatase activity., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 2,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 2,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "record_id": "A0A8M2BDL9-1",
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        "kg_view_protein": true
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    {
        "uniprot_canonical_ac": "A0A8M2BG09-1",
        "uniprot_id": [
            {
                "id": "A0A8M2BG09_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M2BG09",
                "type": "external"
            }
        ],
        "mass": 96435.0,
        "length": 841,
        "protein_name": "Leucine rich repeat containing 8 VRAC subunit Db isoform X1",
        "gene_name": "lrrc8db",
        "organism": "Zebrafish",
        "refseq_name": "leucine rich repeat containing 8 VRAC subunit Db isoform X1",
        "refseq_ac": [
            {
                "id": "XP_005168797",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168797",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "lrrc8db; lrrc8d; zgc:153223",
        "gene_names_refseq": "lrrc8db; lrrc8d; zgc:153223",
        "protein_names_uniprotkb": "Leucine rich repeat containing 8 VRAC subunit Db isoform X1",
        "protein_names_refseq": "leucine rich repeat containing 8 VRAC subunit Db isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005168797.2. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "ec_number_list": [
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                "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2",
                "type": "external"
            },
            {
                "id": "5.6.1.6",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6",
                "type": "external"
            },
            {
                "id": "7.6.2.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3",
                "type": "external"
            }
        ],
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        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8M2BG09-1",
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        "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8M3B6W3-1",
        "uniprot_id": [
            {
                "id": "A0A8M3B6W3_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M3B6W3",
                "type": "external"
            }
        ],
        "mass": 33889.0,
        "length": 298,
        "protein_name": "GTP-binding protein",
        "gene_name": "rem1",
        "organism": "Zebrafish",
        "refseq_name": "GTP-binding protein REM 1 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_009304297",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304297",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "rem1; GEM; SI:zK76P14.3; horizin; rem; zgc:56144",
        "gene_names_refseq": "GEM; SI:zK76P14.3; horizin; rem1; rem; zgc:56144",
        "protein_names_uniprotkb": "GTP-binding protein",
        "protein_names_refseq": "GTP-binding protein REM 1 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009304297.1. COMPLETENESS: full length., [RefSeq]; Binds GTP saturably and exhibits a low intrinsic rate of GTP hydrolysis., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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    },
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            {
                "id": "A0A8M9Q5G5_DANRE",
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            {
                "id": "XP_021328585",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328585",
                "type": "external"
            }
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        "protein_names_refseq": "ribosomal RNA-processing protein 8",
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        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021335623",
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        "protein_names_uniprotkb": "U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 isoform X1",
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        "gene_name": "nme2a",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021335425",
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        "kg_view_protein": true
    },
    {
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        ],
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            }
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        "protein_names_uniprotkb": "Endonuclease 8-like 3; 4.2.99.18; DNA glycosylase/AP lyase Neil3; Endonuclease VIII-like 3; Nei-like protein 3",
        "protein_names_refseq": "endonuclease 8-like 3 isoform X1",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18",
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            {
                "id": "5.6.2.4",
                "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4",
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            },
            {
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            {
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        ],
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        "protein_name": "Ataxin-1a isoform X1",
        "gene_name": "atxn1a",
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        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038291",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "atxn1a; atxn1b; si:ch211-125a6.1",
        "gene_names_refseq": "atxn1a; atxn1b; si:ch211-125a6.1",
        "protein_names_uniprotkb": "Ataxin-1a isoform X1",
        "protein_names_refseq": "ataxin-1a",
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        ],
        "mass": 48522.0,
        "length": 434,
        "protein_name": "DNA repair protein RAD52 homolog",
        "gene_name": "rad52",
        "organism": "Zebrafish",
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            {
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        "gene_names_refseq": "rad52; zgc:112400",
        "protein_names_uniprotkb": "DNA repair protein RAD52 homolog",
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        "disease": "nicotine dependence (Disease Ontology:DOID:0050742); salivary gland carcinoma (Disease Ontology:DOID:0050904); lung cancer (Disease Ontology:DOID:1324); colon cancer (Disease Ontology:DOID:219); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); mucoepidermoid carcinoma (Disease Ontology:DOID:4531); lung small cell carcinoma (Disease Ontology:DOID:5409); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256); nasopharynx carcinoma (Disease Ontology:DOID:9261)",
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        ],
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        "organism": "Zebrafish",
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        "gene_names_uniprotkb": "uts2r3",
        "gene_names_refseq": "uts2r3",
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        ],
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        "gene_name": "si:cabz01021426.2",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:cabz01021426.2",
        "refseq_ac": [
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                "type": "external"
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        ],
        "gene_names_uniprotkb": "si:cabz01021426.2",
        "gene_names_refseq": "si:cabz01021426.2",
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        "protein_names_refseq": "uncharacterized protein si:cabz01021426.2",
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        "predicted_glycosites": 0,
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        "record_id": "A0AA54CD81-1",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AA54CSY2-1",
        "uniprot_id": [
            {
                "id": "A0AA54CSY2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA54CSY2",
                "type": "external"
            }
        ],
        "mass": 38438.0,
        "length": 329,
        "protein_name": "Bis(monoacylglycero)phosphate synthase CLN5",
        "gene_name": "cln5",
        "organism": "Zebrafish",
        "refseq_name": "bis(monoacylglycero)phosphate synthase CLN5",
        "refseq_ac": [
            {
                "id": "XP_009302855",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302855",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cln5",
        "gene_names_refseq": "cln5",
        "protein_names_uniprotkb": "Bis(monoacylglycero)phosphate synthase CLN5; Ceroid-lipofuscinosis neuronal protein 5; Palmitoyl protein thioesterase CLN5; S-depalmitoylase CLN5",
        "protein_names_refseq": "bis(monoacylglycero)phosphate synthase CLN5",
        "tax_id": 7955,
        "disease": "neuronal ceroid lipofuscinosis 5 (Disease Ontology:DOID:0110728)",
        "pathway": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009302855.1. COMPLETENESS: full length., [RefSeq]; Catalyzes the synthesis of bis(monoacylglycero)phosphate (BMP) via transacylation of 2 molecules of lysophosphatidylglycerol (LPG). BMP also known as lysobisphosphatidic acid plays a key role in the formation of intraluminal vesicles and in maintaining intracellular cholesterol homeostasis. Can use only LPG as the exclusive lysophospholipid acyl donor for base exchange and displays BMP synthase activity towards various LPGs (LPG 14:0, LPG 16:0, LPG 18:0, LPG 18:1) with a higher preference for longer chain lengths. Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane., [UniProtKB, UniProtKB]; Exhibits palmitoyl protein thioesterase (S-depalmitoylation) activity in vitro and most likely plays a role in protein S-depalmitoylation., [UniProtKB, UniProtKB]",
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        "ec_number_list": [
            {
                "id": "3.1.2.22",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22",
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            {
                "id": "3.4.19.12",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12",
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            {
                "id": "3.1.1.93",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.93",
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            {
                "id": "3.1.2.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2",
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    {
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            {
                "id": "A0AA57WKX4_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA57WKX4",
                "type": "external"
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        ],
        "mass": 83142.0,
        "length": 729,
        "protein_name": "Mitogen-activated protein kinase 6",
        "gene_name": "mapk6",
        "organism": "Zebrafish",
        "refseq_name": "mitogen-activated protein kinase 6 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_073785424",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073785424",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "mapk6; erk3; p97mapk; si:ch211-235f12.1",
        "gene_names_refseq": "erk3; mapk6; p97mapk; si:ch211-235f12.1",
        "protein_names_uniprotkb": "Mitogen-activated protein kinase 6; 2.7.11.24",
        "protein_names_refseq": "mitogen-activated protein kinase 6 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "ec_number_list": [
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1",
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                "id": "2.7.11.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13",
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            {
                "id": "2.7.11.25",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25",
                "type": "external"
            },
            {
                "id": "2.7.10.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1",
                "type": "external"
            },
            {
                "id": "2.7.11.22",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22",
                "type": "external"
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                "id": "2.7.11.21",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21",
                "type": "external"
            },
            {
                "id": "2.7.11.17",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17",
                "type": "external"
            },
            {
                "id": "2.7.12.1",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1",
                "type": "external"
            },
            {
                "id": "2.7.12.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2",
                "type": "external"
            },
            {
                "id": "2.7.11.24",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24",
                "type": "external"
            },
            {
                "id": "2.7.10.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2",
                "type": "external"
            },
            {
                "id": "2.7.11.23",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23",
                "type": "external"
            },
            {
                "id": "2.7.1.150",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150",
                "type": "external"
            },
            {
                "id": "2.7.11.12",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12",
                "type": "external"
            },
            {
                "id": "2.7.11.39",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39",
                "type": "external"
            },
            {
                "id": "2.7.11.11",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11",
                "type": "external"
            },
            {
                "id": "2.7.1.153",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153",
                "type": "external"
            },
            {
                "id": "2.7.1.137",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137",
                "type": "external"
            },
            {
                "id": "2.7.1.154",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154",
                "type": "external"
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            {
                "id": "2.7.11.26",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26",
                "type": "external"
            },
            {
                "id": "2.7.11.31",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0016301 kinase activity",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AA57WKX4-1",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AA70QHQ6-1",
        "uniprot_id": [
            {
                "id": "A0AA70QHQ6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA70QHQ6",
                "type": "external"
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        ],
        "mass": 63988.0,
        "length": 566,
        "protein_name": "Probable cysteine--tRNA ligase, mitochondrial",
        "gene_name": "cars2",
        "organism": "Zebrafish",
        "refseq_name": "probable cysteine--tRNA ligase, mitochondrial",
        "refseq_ac": [
            {
                "id": "XP_682732",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_682732",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "cars2",
        "gene_names_refseq": "cars2",
        "protein_names_uniprotkb": "Probable cysteine--tRNA ligase, mitochondrial; 6.1.1.16; Cysteinyl-tRNA synthetase",
        "protein_names_refseq": "probable cysteine--tRNA ligase, mitochondrial",
        "tax_id": 7955,
        "disease": "combined oxidative phosphorylation deficiency 27 (Disease Ontology:DOID:0111489)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_682732.4. COMPLETENESS: full length., [RefSeq]; In addition to its role as an aminoacyl-tRNA synthetase, has also cysteine persulfide synthase activity. Produces reactive persulfide species such as cysteine persulfide (CysSSH) from substrate cysteine and mediate direct incorporation of CysSSH into proteins during translations, resulting in protein persulfides and polysulfides. CysSSHs behave as potent antioxidants and cellular protectants., [UniProtKB, UniProtKB]; Mitochondrial cysteine-specific aminoacyl-tRNA synthetase that catalyzes the ATP-dependent ligation of cysteine to tRNA(Cys)., [UniProtKB, UniProtKB]",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.16",
                "type": "external"
            }
        ],
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    {
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            {
                "id": "A0AA70QPX0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA70QPX0",
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        ],
        "mass": 51879.0,
        "length": 448,
        "protein_name": "TNFAIP3-interacting protein 2",
        "gene_name": "tnip2",
        "organism": "Zebrafish",
        "refseq_name": "TNFAIP3-interacting protein 2",
        "refseq_ac": [
            {
                "id": "XP_692717",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692717",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "tnip2",
        "gene_names_refseq": "tnip2",
        "protein_names_uniprotkb": "TNFAIP3-interacting protein 2; A20-binding inhibitor of NF-kappa-B activation 2",
        "protein_names_refseq": "TNFAIP3-interacting protein 2",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_692717.4. COMPLETENESS: full length., [RefSeq]; Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation. Involved in activation of the MEK/ERK signaling pathway during innate immune response; this function seems to be stimulus- and cell type specific. Required for stability of MAP3K8. Involved in regulation of apoptosis in endothelial cells; promotes TEK agonist-stimulated endothelial survival. May act as transcriptional coactivator when translocated to the nucleus. Enhances CHUK-mediated NF-kappa-B activation involving NF-kappa-B p50-p65 and p50-c-Rel complexes., [UniProtKB, UniProtKB]",
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        "mass": 50005.0,
        "length": 450,
        "protein_name": "Dopamine receptor D2 like isoform X1",
        "gene_name": "drd2l",
        "organism": "Zebrafish",
        "refseq_name": "dopamine receptor D2 like isoform X1",
        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070012",
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        "gene_names_refseq": "drd2b; drd2l",
        "protein_names_uniprotkb": "Dopamine receptor D2 like isoform X1",
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        "kg_view_protein": true
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    {
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        "uniprot_id": [
            {
                "id": "A0A8M2B497_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M2B497",
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            }
        ],
        "mass": 79947.0,
        "length": 700,
        "protein_name": "Mitochondrial intermediate peptidase",
        "gene_name": "mipepa",
        "organism": "Zebrafish",
        "refseq_name": "mitochondrial intermediate peptidase",
        "refseq_ac": [
            {
                "id": "XP_005157534",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157534",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "mipepa",
        "gene_names_refseq": "mipepa",
        "protein_names_uniprotkb": "Mitochondrial intermediate peptidase; 3.4.24.59",
        "protein_names_refseq": "mitochondrial intermediate peptidase",
        "tax_id": 7955,
        "disease": "combined oxidative phosphorylation deficiency 31 (Disease Ontology:DOID:0111488); lipodystrophy (Disease Ontology:DOID:811)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005157534.1. COMPLETENESS: full length., [RefSeq]; Cleaves proteins, imported into the mitochondrion, to their mature size., [UniProtKB, UniProtKB]",
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    {
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                "url": "https://www.uniprot.org/uniprot/A0A8M2B6M1",
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        ],
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        "length": 401,
        "protein_name": "Transcription elongation factor A N-terminal and central domain-containing protein",
        "gene_name": "tceanc",
        "organism": "Zebrafish",
        "refseq_name": "transcription elongation factor A N-terminal and central domain-containing protein",
        "refseq_ac": [
            {
                "id": "XP_005160033",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005160033",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "tceanc",
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        "protein_names_uniprotkb": "Transcription elongation factor A N-terminal and central domain-containing protein",
        "protein_names_refseq": "transcription elongation factor A N-terminal and central domain-containing protein",
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        "missing_score": 10000,
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        "kg_view_protein": true
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    {
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                "id": "A0A8M2B7N0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M2B7N0",
                "type": "external"
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        ],
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        "length": 779,
        "protein_name": "Ankyrin repeat and EF-hand domain-containing protein 1 isoform X1",
        "gene_name": "ankef1a",
        "organism": "Zebrafish",
        "refseq_name": "ankyrin repeat and EF-hand domain-containing protein 1",
        "refseq_ac": [
            {
                "id": "NP_001020714",
                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020714",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "ankef1a; ankrd5a; si:dkey-20n10.1",
        "gene_names_refseq": "ankef1a; ankrd5a; si:dkey-20n10.1",
        "protein_names_uniprotkb": "Ankyrin repeat and EF-hand domain-containing protein 1 isoform X1",
        "protein_names_refseq": "ankyrin repeat and EF-hand domain-containing protein 1a; ankyrin repeat and EF-hand domain-containing protein 1; ankyrin repeat domain 5a",
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        "predicted_glycosites": 3,
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        "kg_view_protein": true
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    {
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        "protein_name": "Stonustoxin subunit beta-like",
        "gene_name": "LOC796214",
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        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161889",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC796214",
        "gene_names_refseq": "LOC796214",
        "protein_names_uniprotkb": "Stonustoxin subunit beta-like",
        "protein_names_refseq": "stonustoxin subunit beta-like",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005161889.2. COMPLETENESS: full length., [RefSeq]",
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        "missing_score": 10000,
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        "kg_view_protein": true
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    {
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                "id": "A0A8M2B9H6_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8M2B9H6",
                "type": "external"
            }
        ],
        "mass": 51448.0,
        "length": 480,
        "protein_name": "Solute carrier family 41 member",
        "gene_name": "slc41a3",
        "organism": "Zebrafish",
        "refseq_name": "solute carrier family 41 member 1 isoform X1",
        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073795362",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "slc41a3; LOC564564",
        "gene_names_refseq": "LOC564564",
        "protein_names_uniprotkb": "Solute carrier family 41 member",
        "protein_names_refseq": "solute carrier family 41 member 1 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as a magnesium transporter., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "secondary_ac_list": "A0AC58IM93;A0AC58IM95;A0AC58IMA0",
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        "kg_view_protein": true
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    {
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        ],
        "mass": 37752.0,
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        "protein_name": "Caspase 8, apoptosis-related cysteine peptidase, like 1 isoform X1",
        "gene_name": "casp8l1",
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        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165879",
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        ],
        "gene_names_uniprotkb": "casp8l1; casp8b",
        "gene_names_refseq": "casp8b; casp8l1",
        "protein_names_uniprotkb": "Caspase 8, apoptosis-related cysteine peptidase, like 1 isoform X1",
        "protein_names_refseq": "caspase 8, apoptosis-related cysteine peptidase, like 1 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005165879.2. COMPLETENESS: full length., [RefSeq]",
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            },
            {
                "id": "7.6.2.3",
                "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3",
                "type": "external"
            }
        ],
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        "kg_view_protein": true
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    {
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            {
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                "url": "https://www.uniprot.org/uniprot/A0A8M3AI97",
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        ],
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        "length": 317,
        "protein_name": "Olfactory receptor 52A5",
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            {
                "id": "XP_009289741",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009289741",
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        ],
        "gene_names_uniprotkb": "or55c1",
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        "protein_names_refseq": "olfactory receptor 52A5",
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                "url": "https://www.uniprot.org/uniprot/A0A8M3ARL6",
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        ],
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        "length": 306,
        "protein_name": "Homeobox protein Hox-C11a",
        "gene_name": "hoxc11b",
        "organism": "Zebrafish",
        "refseq_name": "homeobox protein Hox-C11a",
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            {
                "id": "XP_009298848",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009298848",
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        "protein_names_uniprotkb": "Homeobox protein Hox-C11a",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009298848.1. COMPLETENESS: full length., [RefSeq]; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB, UniProtKB]",
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        ],
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        "gene_name": "si:ch211-149k23.9",
        "organism": "Zebrafish",
        "refseq_name": "germ cell-specific gene 1-like protein",
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            {
                "id": "XP_073782042",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073782042",
                "type": "external"
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        ],
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        "gene_names_refseq": "si:ch211-149k23.9",
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        "protein_names_refseq": "germ cell-specific gene 1-like protein",
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        ],
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        "gene_name": "crp6",
        "organism": "Zebrafish",
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                "id": "XP_009295908",
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        ],
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        "gene_names_refseq": "crp6; si:ch211-234p6.8",
        "protein_names_uniprotkb": "Pentraxin family member",
        "protein_names_refseq": "C-reactive protein 6 isoform X1",
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    {
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        ],
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        "gene_name": "LOC101883431",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26",
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                "id": "2.7.11.31",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329212",
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        ],
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        "gene_names_refseq": "corin",
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        ],
        "mass": 35417.0,
        "length": 317,
        "protein_name": "Ankyrin repeat domain-containing protein 1",
        "gene_name": "ankrd1a",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328823",
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        "protein_names_uniprotkb": "Ankyrin repeat domain-containing protein 1",
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        "disease": "hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); spinal muscular atrophy (Disease Ontology:DOID:12377); dilated cardiomyopathy (Disease Ontology:DOID:12930); nemaline myopathy (Disease Ontology:DOID:3191); congenital structural myopathy (Disease Ontology:DOID:422)",
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        "protein_names_uniprotkb": "Transmembrane protein 150C",
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        ],
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        "length": 192,
        "protein_name": "Protein Mis18-alpha",
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            {
                "id": "XP_021328060",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1",
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                "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24",
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        "refseq_ac": [
            {
                "id": "XP_688721",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688721",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "coro2ba",
        "gene_names_refseq": "coro2ba",
        "protein_names_uniprotkb": "Coronin",
        "protein_names_refseq": "coronin-2B isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_688721.3. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
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        "record_id": "A0A8N7TAY8-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8N7TCP8-1",
        "uniprot_id": [
            {
                "id": "A0A8N7TCP8_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8N7TCP8",
                "type": "external"
            }
        ],
        "mass": 109410.0,
        "length": 960,
        "protein_name": "Aminopeptidase",
        "gene_name": "anpepa",
        "organism": "Zebrafish",
        "refseq_name": "aminopeptidase N",
        "refseq_ac": [
            {
                "id": "XP_682987",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_682987",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "anpepa",
        "gene_names_refseq": "anpepa",
        "protein_names_uniprotkb": "Aminopeptidase; 3.4.11.-",
        "protein_names_refseq": "aminopeptidase N",
        "tax_id": 7955,
        "disease": "severe acute respiratory syndrome (Disease Ontology:DOID:2945)",
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        "pathway_count": 0,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_682987.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "predicted_o_glycosites": 1,
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        "reported_c_glycosites_with_glycan": 0,
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        "ec_number_list": [],
        "go_molecular_function": "GO:0004177 aminopeptidase activity",
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        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8N7TE86-1",
        "uniprot_id": [
            {
                "id": "A0A8N7TE86_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8N7TE86",
                "type": "external"
            }
        ],
        "mass": 50596.0,
        "length": 463,
        "protein_name": "Lysosomal proton-coupled steroid conjugate and bile acid symporter SLC46A3",
        "gene_name": "si:dkey-5g14.1",
        "organism": "Zebrafish",
        "refseq_name": "lysosomal proton-coupled steroid conjugate and bile acid symporter SLC46A3",
        "refseq_ac": [
            {
                "id": "XP_684413",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_684413",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:dkey-5g14.1",
        "gene_names_refseq": "si:dkey-5g14.1",
        "protein_names_uniprotkb": "Lysosomal proton-coupled steroid conjugate and bile acid symporter SLC46A3",
        "protein_names_refseq": "lysosomal proton-coupled steroid conjugate and bile acid symporter SLC46A3",
        "tax_id": 7955,
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        "pathway_count": 0,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_684413.5. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
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        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
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        "record_id": "A0A8N7TE86-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0A8N7UVS2-1",
        "uniprot_id": [
            {
                "id": "A0A8N7UVS2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0A8N7UVS2",
                "type": "external"
            }
        ],
        "mass": 25553.0,
        "length": 229,
        "protein_name": "Intraflagellar transport-associated protein",
        "gene_name": "iftap",
        "organism": "Zebrafish",
        "refseq_name": "intraflagellar transport-associated protein",
        "refseq_ac": [
            {
                "id": "XP_706374",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_706374",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "iftap",
        "gene_names_refseq": "iftap",
        "protein_names_uniprotkb": "Intraflagellar transport-associated protein",
        "protein_names_refseq": "intraflagellar transport-associated protein",
        "tax_id": 7955,
        "disease": "",
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        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_706374.4. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
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        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
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        "reported_snv": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
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        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0A8N7UVS2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AA52K6S0-1",
        "uniprot_id": [
            {
                "id": "A0AA52K6S0_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA52K6S0",
                "type": "external"
            }
        ],
        "mass": 40885.0,
        "length": 368,
        "protein_name": "Inhibin beta B chain",
        "gene_name": "LOC100329520",
        "organism": "Zebrafish",
        "refseq_name": "inhibin beta B chain",
        "refseq_ac": [
            {
                "id": "XP_002662616",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002662616",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "LOC100329520",
        "gene_names_refseq": "LOC100329520",
        "protein_names_uniprotkb": "Inhibin beta B chain",
        "protein_names_refseq": "inhibin beta B chain",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_002662616.2. COMPLETENESS: full length., [RefSeq]; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "go_biological_process": "",
        "synthesized_glycan_count": 0,
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        "record_id": "A0AA52K6S0-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AA52K7H2-1",
        "uniprot_id": [
            {
                "id": "A0AA52K7H2_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA52K7H2",
                "type": "external"
            }
        ],
        "mass": 60163.0,
        "length": 553,
        "protein_name": "Glutathione hydrolase",
        "gene_name": "ggt5b",
        "organism": "Zebrafish",
        "refseq_name": "glutathione hydrolase 5 proenzyme",
        "refseq_ac": [
            {
                "id": "XP_002667883",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002667883",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "ggt5b",
        "gene_names_refseq": "ggt5b",
        "protein_names_uniprotkb": "Glutathione hydrolase; 2.3.2.2; 3.4.19.13; Gamma-glutamyltransferase; Gamma-glutamyltranspeptidase",
        "protein_names_refseq": "glutathione hydrolase 5 proenzyme",
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_002667883.3. COMPLETENESS: full length., [RefSeq]; Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 2,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 2,
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        "total_reported_n_glycosites": 0,
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        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [
            {
                "id": "2.3.2.2",
                "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.2",
                "type": "external"
            },
            {
                "id": "3.4.19.13",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.13",
                "type": "external"
            }
        ],
        "go_molecular_function": "GO:0016787 hydrolase activity",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AA52K7H2-1",
        "record_type": "protein",
        "filter_code": "0000000.0000000.100000.000000000000000001.0000000001000.001.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AA52K968-1",
        "uniprot_id": [
            {
                "id": "A0AA52K968_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AA52K968",
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            }
        ],
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        "length": 1098,
        "protein_name": "Semaphorin-5A",
        "gene_name": "sema5bb",
        "organism": "Zebrafish",
        "refseq_name": "semaphorin-5B",
        "refseq_ac": [
            {
                "id": "XP_001340298",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001340298",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "sema5bb",
        "gene_names_refseq": "sema5bb",
        "protein_names_uniprotkb": "Semaphorin-5A; Semaphorin-F",
        "protein_names_refseq": "semaphorin-5B",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_001340298.5. COMPLETENESS: full length., [RefSeq]; Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "kg_view_protein": true
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        ],
        "mass": 131074.0,
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        "protein_name": "Proline-, glutamic acid- and leucine-rich protein 1",
        "gene_name": "pelp1",
        "organism": "Zebrafish",
        "refseq_name": "proline-, glutamic acid- and leucine-rich protein 1",
        "refseq_ac": [
            {
                "id": "XP_001339018",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001339018",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "pelp1",
        "gene_names_refseq": "pelp1",
        "protein_names_uniprotkb": "Proline-, glutamic acid- and leucine-rich protein 1; Modulator of non-genomic activity of estrogen receptor",
        "protein_names_refseq": "proline-, glutamic acid- and leucine-rich protein 1",
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        "missing_score": 10000,
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        "kg_view_protein": true
    },
    {
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        ],
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        "length": 220,
        "protein_name": "Transmembrane emp24 domain-containing protein 11",
        "gene_name": "si:ch211-255i20.3",
        "organism": "Zebrafish",
        "refseq_name": "transmembrane emp24 domain-containing protein 11",
        "refseq_ac": [
            {
                "id": "XP_003199913",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003199913",
                "type": "external"
            }
        ],
        "gene_names_uniprotkb": "si:ch211-255i20.3",
        "gene_names_refseq": "si:ch211-255i20.3",
        "protein_names_uniprotkb": "Transmembrane emp24 domain-containing protein 11",
        "protein_names_refseq": "transmembrane emp24 domain-containing protein 11",
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        ],
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        "protein_name": "Uncharacterized protein si:dkeyp-69b9.3",
        "gene_name": "si:dkeyp-69b9.3",
        "organism": "Zebrafish",
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157961",
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        ],
        "gene_names_uniprotkb": "si:dkeyp-69b9.3",
        "gene_names_refseq": "si:dkeyp-69b9.3",
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        "protein_names_refseq": "uncharacterized protein si:dkeyp-69b9.3",
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    {
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        ],
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        ],
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        ],
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                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107108",
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        "gene_names_refseq": "sncaip; zgc:172291",
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        "protein_names_refseq": "synphilin-1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:796993)",
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        "gene_name": "pik3ap1",
        "organism": "Zebrafish",
        "refseq_name": "phosphoinositide 3-kinase adapter protein 1",
        "refseq_ac": [
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        "protein_names_refseq": "phosphoinositide 3-kinase adapter protein 1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        ],
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        "length": 446,
        "protein_name": "U6 snRNA (Guanine-N(2))-methyltransferase THUMPD2",
        "gene_name": "thumpd2",
        "organism": "Zebrafish",
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        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691263",
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        "protein_names_uniprotkb": "U6 snRNA (Guanine-N(2))-methyltransferase THUMPD2",
        "protein_names_refseq": "U6 snRNA (guanine-N(2))-methyltransferase THUMPD2",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_691263.4. COMPLETENESS: full length., [RefSeq]",
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        ],
        "mass": 25166.0,
        "length": 219,
        "protein_name": "Ectodysplasin-A receptor-associated adapter protein",
        "gene_name": "edaradd",
        "organism": "Zebrafish",
        "refseq_name": "ectodysplasin-A receptor-associated adapter protein",
        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695138",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "edaradd",
        "gene_names_refseq": "edaradd",
        "protein_names_uniprotkb": "Ectodysplasin-A receptor-associated adapter protein",
        "protein_names_refseq": "ectodysplasin-A receptor-associated adapter protein",
        "tax_id": 7955,
        "disease": "ectodermal dysplasia 11A (Disease Ontology:DOID:0111653); ectodermal dysplasia 11B (Disease Ontology:DOID:0111654)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_695138.4. COMPLETENESS: full length., [RefSeq]; Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA signaling pathway during morphogenesis of ectodermal organs. Mediates the activation of NF-kappa-B., [UniProtKB, UniProtKB]",
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    {
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        ],
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        "length": 206,
        "protein_name": "Uncharacterized protein si:dkeyp-69c1.9",
        "gene_name": "si:dkeyp-69c1.9",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:dkeyp-69c1.9",
        "refseq_ac": [
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        ],
        "gene_names_uniprotkb": "si:dkeyp-69c1.9",
        "gene_names_refseq": "si:dkeyp-69c1.9",
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        "protein_names_refseq": "uncharacterized protein si:dkeyp-69c1.9",
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    {
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        ],
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        "protein_name": "Rho GTPase-activating protein 22",
        "gene_name": "arhgap22b",
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            }
        ],
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            },
            {
                "id": "3.1.4.53",
                "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.53",
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            }
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        ],
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        ],
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        ],
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        "length": 419,
        "protein_name": "Fumarylacetoacetase",
        "gene_name": "fah",
        "organism": "Zebrafish",
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        "refseq_ac": [
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                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428711",
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        "gene_names_refseq": "fah; fb59b12; wu:fb59b12; zgc:55316",
        "protein_names_uniprotkb": "Fumarylacetoacetase; 3.7.1.2; Fumarylacetoacetate hydrolase",
        "protein_names_refseq": "fumarylacetoacetase isoform 4",
        "tax_id": 7955,
        "disease": "tyrosinemia type I (Disease Ontology:DOID:0050726); hypertension (Disease Ontology:DOID:10763); liver cirrhosis (Disease Ontology:DOID:5082)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588727.2108143.1, SRR32588728.8257142.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On Jul 2, 2025 this sequence version replaced XP_073762277.1., [RefSeq]",
        "predicted_glycosites": 0,
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        "gene_name": "sall3a",
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        "refseq_name": "sal-like protein 3 isoform X1",
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        "protein_names_refseq": "sal-like protein 3 isoform X1",
        "tax_id": 7955,
        "disease": "carcinoma (Disease Ontology:DOID:305)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_068074900.1. COMPLETENESS: full length., [RefSeq]; Probable transcription factor., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Transcriptional repressor involved in organogenesis. Plays an essential role in ureteric bud invasion during kidney development., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "length": 382,
        "protein_name": "Nucleosome assembly protein 1-like 4b isoform X1",
        "gene_name": "nap1l4b",
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        ],
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        "length": 873,
        "protein_name": "Lysine (K)-specific demethylase 2Ba isoform X1",
        "gene_name": "kdm2ba",
        "organism": "Zebrafish",
        "refseq_name": "lysine (K)-specific demethylase 2Ba isoform X1",
        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068079013",
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            }
        ],
        "gene_names_uniprotkb": "kdm2ba; fbxl10; wu:fd13a09; zgc:85787",
        "gene_names_refseq": "fbxl10; kdm2ba; wu:fd13a09; zgc:85787",
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        "gene_names_uniprotkb": "adgre9",
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        "protein_names_refseq": "adhesion G protein-coupled receptor E1 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "gene_name": "LOC101883942",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        ],
        "mass": 50957.0,
        "length": 454,
        "protein_name": "12S rRNA N(4)-cytidine methyltransferase METTL15",
        "gene_name": "mettl15",
        "organism": "Zebrafish",
        "refseq_name": "12S rRNA N(4)-cytidine methyltransferase METTL15 isoform X1",
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            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073762849",
                "type": "external"
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        ],
        "gene_names_uniprotkb": "mettl15",
        "gene_names_refseq": "mettl15",
        "protein_names_uniprotkb": "12S rRNA N(4)-cytidine methyltransferase METTL15; Methyltransferase 5 domain-containing protein 1; Methyltransferase-like protein 15",
        "protein_names_refseq": "12S rRNA N(4)-cytidine methyltransferase METTL15 isoform X1",
        "tax_id": 7955,
        "disease": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; N4-methylcytidine (m4C) methyltransferase responsible for the methylation of position C839 in mitochondrial 12S rRNA. Involved in the stabilization of 12S rRNA folding, therefore facilitating the assembly of the mitochondrial small ribosomal subunits., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        ],
        "mass": 67236.0,
        "length": 585,
        "protein_name": "Synovial sarcoma, X breakpoint 2 interacting protein a isoform X1",
        "gene_name": "ssx2ipa",
        "organism": "Zebrafish",
        "refseq_name": "synovial sarcoma, X breakpoint 2 interacting protein a",
        "refseq_ac": [
            {
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                "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957129",
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        ],
        "gene_names_uniprotkb": "ssx2ipa; ssx2ip; zgc:73314",
        "gene_names_refseq": "ssx2ipa; ssx2ip; zgc:73314",
        "protein_names_uniprotkb": "Synovial sarcoma, X breakpoint 2 interacting protein a isoform X1",
        "protein_names_refseq": "SSC2IP; synovial sarcoma, X breakpoint 2 interacting protein a",
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        "pathway": " (dre:393808)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01001143.1, GDQQ01022699.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000002.1. On Jun 25, 2025 this sequence version replaced NP_957129.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
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        "gene_name": "si:dkey-83f18.3",
        "organism": "Zebrafish",
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                "id": "XP_073762021",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073762021",
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            }
        ],
        "gene_names_uniprotkb": "si:dkey-83f18.3",
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        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100002910)",
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        "publication_id_list": "21873635",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "reported_n_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
        "record_id": "A0AC58FWQ1-1",
        "record_type": "protein",
        "filter_code": "0000000.0000101.100000.000000000000000001.0000000000000.000.00000",
        "kg_view_protein": true
    },
    {
        "uniprot_canonical_ac": "A0AC58FZ12-1",
        "uniprot_id": [
            {
                "id": "A0AC58FZ12_DANRE",
                "url": "https://www.uniprot.org/uniprot/A0AC58FZ12",
                "type": "external"
            }
        ],
        "mass": 40586.0,
        "length": 361,
        "protein_name": "Novel immune-type receptor 12 isoform X1",
        "gene_name": "nitr12",
        "organism": "Zebrafish",
        "refseq_name": "novel immune-type receptor 12 isoform X1",
        "refseq_ac": [
            {
                "id": "XP_073762774",
                "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073762774",
                "type": "external"
            }
        ],
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        "gene_names_refseq": "nitr12_1; nitr12",
        "protein_names_uniprotkb": "Novel immune-type receptor 12 isoform X1",
        "protein_names_refseq": "novel immune-type receptor 12 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:557932)",
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        "publication_id_list": "18565225;20012603",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": [],
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0009617 response to bacterium;GO:0002376 immune system process",
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        "kg_view_protein": true
    }
]
