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cardiovascular system disease (Disease Ontology:DOID:1287); lung cancer (Disease Ontology:DOID:1324); cystic fibrosis (Disease Ontology:DOID:1485); renovascular hypertension (Disease Ontology:DOID:1591); keratosis (Disease Ontology:DOID:161); cystitis (Disease Ontology:DOID:1679); pancreatic cancer (Disease Ontology:DOID:1793); asthma (Disease Ontology:DOID:2841); glomerulonephritis (Disease Ontology:DOID:2921); acute kidney failure (Disease Ontology:DOID:3021); interstitial lung disease (Disease Ontology:DOID:3082); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); liver cirrhosis (Disease Ontology:DOID:5082); hepatocellular carcinoma (Disease Ontology:DOID:684); end stage renal disease (Disease Ontology:DOID:783); lung disease (Disease Ontology:DOID:850); vasculitis (Disease Ontology:DOID:865); bacterial pneumonia (Disease Ontology:DOID:874); status asthmaticus (Disease Ontology:DOID:9362)", "pathway": " (R-RNO-6798695); (R-RNO-8941413)", "pathway_count": 2, 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"refseq_ac": [], "gene_names_uniprotkb": "N4bp2l1", "gene_names_refseq": "", "protein_names_uniprotkb": "NEDD4 binding protein 2-like 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1B7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1E3-1", "uniprot_id": [ { "id": "A0A0G2K1E3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1E3", "type": "external" } ], "mass": 294918.0, "length": 2714, "protein_name": "Histone-lysine N-methyltransferase 2B", "gene_name": "Kmt2b", "organism": "Rat", "refseq_name": "histone-lysine N-methyltransferase 2B", "refseq_ac": [ { "id": "NP_001414070", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414070", "type": "external" } ], "gene_names_uniprotkb": "Kmt2b", "gene_names_refseq": "Kmt2b; Mll4; RGD1308331; Wbp7", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase 2B; 2.1.1.364; Trithorax homolog 2; WW domain-binding protein 7", "protein_names_refseq": "WW domain binding protein 7; histone-lysine N-methyltransferase 2B-like; histone-lysine N-methyltransferase 2B; lysine (K)-specific methyltransferase 2B; myeloid/lymphoid or mixed-lineage leukemia 4", "tax_id": 10116, "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861); dystonia 28, childhood-onset (Disease Ontology:DOID:0060936); autosomal dominant intellectual developmental disorder 68 (Disease Ontology:DOID:0061041); prostate cancer (Disease Ontology:DOID:10283); breast cancer (Disease Ontology:DOID:1612); congenital heart disease (Disease Ontology:DOID:1682); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (rno:102550344); (R-RNO-201722); (R-RNO-3214841); (R-RNO-3769402); (R-RNO-8936459); (R-RNO-9772755)", "pathway_count": 6, "publication_count": 3, "publication_id_list": "22673903;36162497;38876442", "class_list": "", "function": "Histone methyltransferase MLL4 protects against pressure overload-induced heart failure via a THBS4-mediated protection in ER stress., [RefSeq, PubMed]; Histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4) via a non-processive mechanism. Part of chromatin remodeling machinery predominantly forms H3K4me1 and H3K4me2 methylation marks at active chromatin sites where transcription and DNA repair take place. Likely plays a redundant role with KMT2C in enriching H3K4me1 marks on primed and active enhancer elements. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development. Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation., [UniProtKB, UniProtKB, UniProtKB]; KMT2B-dependent RFK transcription activates the TNF-alpha/NOX2 pathway and enhances ferroptosis caused by myocardial ischemia-reperfusion., [RefSeq, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.364", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.364", "type": "external" }, { "id": "2.1.1.370", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.370", "type": "external" }, { "id": "2.1.1.371", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.371", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.85", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.85", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.355", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355", "type": "external" }, { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" }, { "id": "2.1.1.362", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.362", "type": "external" }, { "id": "2.1.1.361", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.361", "type": "external" }, { "id": "2.1.1.319", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.319", "type": "external" }, { "id": "1.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.-", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042800 histone H3K4 methyltransferase activity;GO:0045322 unmethylated CpG binding;GO:0140945 histone H3K4 monomethyltransferase activity;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0035097 histone methyltransferase complex;GO:0044665 MLL1/2 complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0032259 methylation;GO:0006346 DNA methylation-dependent constitutive heterochromatin formation;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2K1E3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1K5-1", "uniprot_id": [ { "id": "A0A0G2K1K5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1K5", "type": "external" } ], "mass": 128376.0, "length": 1133, "protein_name": "Trafficking protein particle complex subunit 11", "gene_name": "Trappc11", "organism": "Rat", "refseq_name": "trafficking protein particle complex subunit 11", "refseq_ac": [ { "id": "NP_001162586", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162586", "type": "external" } ], "gene_names_uniprotkb": "Trappc11", "gene_names_refseq": "RGD1309765; Trappc11", "protein_names_uniprotkb": "Trafficking protein particle complex subunit 11", "protein_names_refseq": "trafficking protein particle complex 11; trafficking protein particle complex subunit 11", "tax_id": 10116, "disease": "autosomal recessive limb-girdle muscular dystrophy type 2S (Disease Ontology:DOID:0110287); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (rno:290746); (R-RNO-8876198)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0030008 TRAPP complex", "go_biological_process": "GO:0016192 vesicle-mediated transport;GO:0045054 constitutive secretory pathway;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030 Golgi organization;GO:0061635 regulation of protein complex stability", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1K5-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1N7-1", "uniprot_id": [ { "id": "A0A0G2K1N7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1N7", "type": "external" } ], "mass": 34093.0, "length": 307, "protein_name": "Olfactory receptor", "gene_name": "Or1j10", "organism": "Rat", "refseq_name": "olfactory receptor Olr399", "refseq_ac": [ { "id": "NP_001000560", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000560", "type": "external" } ], "gene_names_uniprotkb": "Or1j10", "gene_names_refseq": "Olr399; Or1j10", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 399; olfactory receptor Olr399; olfactory receptor gene Olr399", "tax_id": 10116, "disease": "", "pathway": " (rno:366026)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1N7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1Q3-1", "uniprot_id": [ { "id": "A0A0G2K1Q3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1Q3", "type": "external" } ], "mass": 44136.0, "length": 398, "protein_name": "Hexosyltransferase", "gene_name": "B3gnt9", "organism": "Rat", "refseq_name": "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9", "refseq_ac": [ { "id": "NP_001387877", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001387877", "type": "external" } ], "gene_names_uniprotkb": "B3gnt9", "gene_names_refseq": "B3gnt9; RGD1310170", "protein_names_uniprotkb": "Hexosyltransferase; 2.4.1.-", "protein_names_refseq": "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9", "tax_id": 10116, "disease": "", "pathway": " (rno:291958); (R-RNO-913709)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" }, { "id": "2.4.1.206", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.206", "type": "external" } ], "go_molecular_function": "GO:0008194 UDP-glycosyltransferase activity;GO:0016758 hexosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0030311 poly-N-acetyllactosamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1Q3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K229-1", "uniprot_id": [ { "id": "A0A0G2K229_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K229", "type": "external" } ], "mass": 121015.0, "length": 1104, "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 10", "gene_name": "Adamts10", "organism": "Rat", "refseq_name": "A disintegrin and metalloproteinase with thrombospondin motifs 10 precursor", "refseq_ac": [ { "id": "NP_001258374", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258374", "type": "external" } ], "gene_names_uniprotkb": "Adamts10", "gene_names_refseq": "Adamts10", "protein_names_uniprotkb": "A disintegrin and metalloproteinase with thrombospondin motifs 10", "protein_names_refseq": "A disintegrin and metalloproteinase with thrombospondin motifs 10 precursor; A disintegrin and metalloproteinase with thrombospondin motifs 10; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 10; a disintegrin-like and metalloprotease with thrombospondin type 1 motif, 10", "tax_id": 10116, "disease": "Weill-Marchesani syndrome (Disease Ontology:DOID:0050475)", "pathway": " (rno:314655); (R-RNO-5173214)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0031012 extracellular matrix;GO:0001527 microfibril", "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K229-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K2F8-1", "uniprot_id": [ { "id": "A0A0G2K2F8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K2F8", "type": "external" } ], "mass": 209224.0, "length": 1889, "protein_name": "Zinc finger protein 106", "gene_name": "Zfp106", "organism": "Rat", "refseq_name": "zinc finger protein 106", "refseq_ac": [ { "id": "NP_001406800", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001406800", "type": "external" } ], "gene_names_uniprotkb": "Zfp106", "gene_names_refseq": "Zfp106", "protein_names_uniprotkb": "Zinc finger protein 106; Zinc finger protein 474", "protein_names_refseq": "zinc finger protein 106", "tax_id": 10116, "disease": "amyotrophic lateral sclerosis (Disease Ontology:DOID:332)", "pathway": " (rno:688018)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005829 cytosol;GO:0016020 membrane;GO:0016607 nuclear speck", "go_biological_process": "GO:0008286 insulin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K2F8-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K2G2-1", "uniprot_id": [ { "id": "A0A0G2K2G2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K2G2", "type": "external" } ], "mass": 35928.0, "length": 324, "protein_name": "Olfactory receptor", "gene_name": "Or6al1", "organism": "Rat", "refseq_name": "olfactory receptor Olr1", "refseq_ac": [ { "id": "NP_001000538", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000538", "type": "external" } ], "gene_names_uniprotkb": "Or6al1", "gene_names_refseq": "Olr1l; Olr1; Or6al1", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1-like; olfactory receptor Olr1; olfactory receptor gene Olr1", "tax_id": 10116, "disease": "", "pathway": " (rno:365170)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K2G2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K2H0-1", "uniprot_id": [ { "id": "A0A0G2K2H0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K2H0", "type": "external" } ], "mass": 97191.0, "length": 879, "protein_name": "Tyrosine-protein kinase receptor UFO", "gene_name": "Axl", "organism": "Rat", "refseq_name": "tyrosine-protein kinase receptor UFO isoform 2 precursor", "refseq_ac": [ { "id": "NP_001013165", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013165", "type": "external" } ], "gene_names_uniprotkb": "Axl", "gene_names_refseq": "Axl", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor UFO; 2.7.10.1", "protein_names_refseq": "tyrosine-protein kinase receptor UFO isoform 2 precursor; tyrosine-protein kinase receptor UFO", "tax_id": 10116, "disease": "glomerulonephritis (Disease Ontology:DOID:2921); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (rno:308444); (R-RNO-4420097)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "27927649;28386842;31181097;31884887;34678434", "class_list": "", "function": "AXL signaling in primary sensory neurons contributes to chronic compression of dorsal root ganglion-induced neuropathic pain in rats., [RefSeq, PubMed]; Axl expression pattern suggests a role in the early progression of LV remodeling in HF but not in the later systolic dysfunction. Publication Status: Online-Only, [RefSeq, PubMed]; Cilostazol-mediated protection against uremic toxin-related vascular smooth muscle cell dysfunction via Axl signaling pathway., [RefSeq, PubMed]; The Gas6/Axl interaction was inhibited by R428, which abolished the preventive effect of VK2 on CaCl2- and beta-GP-induced apoptosis and calcification. These results suggest that Gas6 is critical in VK2-mediated functions that attenuate CaCl2- and beta-GP-induced VSMC calcification by blocking apoptosis., [RefSeq, PubMed]; Tumor perivascular cell-derived extracellular vesicles promote angiogenesis via the Gas6/Axl pathway., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.10.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.4", "type": "external" }, { "id": "2.7.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.32", "type": "external" }, { "id": "2.7.1.82", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.82", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0019838 growth factor binding;GO:0046872 metal ion binding;GO:0001618 virus receptor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0016020 membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0001779 natural killer cell differentiation;GO:0035457 cellular response to interferon-alpha;GO:0001961 positive regulation of cytokine-mediated signaling pathway;GO:2000669 negative regulation of dendritic cell apoptotic process;GO:0006954 inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0G2K2H0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K2L3-1", "uniprot_id": [ { "id": "A0A0G2K2L3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K2L3", "type": "external" } ], "mass": 15855.0, "length": 145, "protein_name": "Small proline-rich protein 1B", "gene_name": "Sprr1b", "organism": "Rat", "refseq_name": "cornifin-B", "refseq_ac": [ { "id": "NP_001395725", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001395725", "type": "external" } ], "gene_names_uniprotkb": "Sprr1b", "gene_names_refseq": "Sprr1b", "protein_names_uniprotkb": "Small proline-rich protein 1B", "protein_names_refseq": "cornifin-B; small proline-rich protein 1B (cornifin)", "tax_id": 10116, "disease": "", "pathway": " (rno:685912)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0001533 cornified envelope", "go_biological_process": "GO:0030216 keratinocyte differentiation;GO:0018149 peptide cross-linking", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K2L3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K2L5-1", "uniprot_id": [ { "id": "A0A0G2K2L5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K2L5", "type": "external" } ], "mass": 35018.0, "length": 310, "protein_name": "Olfactory receptor", "gene_name": "Or4c121", "organism": "Rat", "refseq_name": "olfactory receptor Olr687", "refseq_ac": [ { "id": "NP_001000356", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000356", "type": "external" } ], "gene_names_uniprotkb": "Or4c121", "gene_names_refseq": "Olr687; Or4c121", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 687; olfactory receptor Olr687; olfactory receptor gene Olr687", "tax_id": 10116, "disease": "", "pathway": " (rno:295892)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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Required for normal fusion of the chorion and the allantois during placenta development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation., [UniProtKB, UniProtKB]; LncRNA OIP5-AS1/miR-410-3p/Wnt7b axis promotes the proliferation of rheumatoid arthritis fibroblast-like synoviocytes via regulating the Wnt/beta-catenin pathway., [RefSeq, PubMed]; Wnt7b/beta-catenin signaling may play an important role infetal rat alveolar epithelial type II cells (fAEC2) transdifferentiation., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, 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"glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0006955 immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K3L5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K3L8-1", "uniprot_id": [ { "id": "A0A0G2K3L8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K3L8", "type": "external" } ], "mass": 46176.0, "length": 410, "protein_name": "WD repeat and FYVE domain-containing protein 1", "gene_name": "Wdfy1", "organism": "Rat", "refseq_name": "WD repeat and FYVE domain-containing protein 1", "refseq_ac": [ { "id": "NP_001380913", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001380913", "type": "external" } ], "gene_names_uniprotkb": "Wdfy1", "gene_names_refseq": 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"protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "Usp45", "organism": "Rat", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 45 isoform X2", "refseq_ac": [ { "id": "XP_006238002", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006238002", "type": "external" } ], "gene_names_uniprotkb": "Usp45", "gene_names_refseq": "Usp45", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 45 isoform X2", "tax_id": 10116, "disease": "Leber congenital amaurosis 19 (Disease Ontology:DOID:0081169)", "pathway": " (rno:313098); (R-RNO-5696395)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the deubiquitination of SPDL1. Plays a role in the repair of UV-induced DNA damage via deubiquitination of ERCC1, promoting its recruitment to DNA damage sites. May be involved in the maintenance of photoreceptor function. May play a role in normal retinal development. Plays a role in cell migration., [UniProtKB, UniProtKB]; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0001917 photoreceptor inner segment", "go_biological_process": "GO:0006281 DNA repair;GO:0006508 proteolysis;GO:0016477 cell migration;GO:0016579 protein deubiquitination;GO:0045494 photoreceptor cell maintenance", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K4S7-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZD24-1", "uniprot_id": [ { "id": "D3ZD24_RAT", "url": "https://www.uniprot.org/uniprot/D3ZD24", "type": "external" } ], "mass": 112194.0, "length": 976, "protein_name": "Nesprin-3", "gene_name": "Syne3", "organism": "Rat", "refseq_name": "nesprin-3", "refseq_ac": [ { "id": "NP_001100232", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100232", "type": "external" } ], "gene_names_uniprotkb": "Syne3", "gene_names_refseq": "RGD1304563; Syne3", "protein_names_uniprotkb": "Nesprin-3; KASH domain-containing protein 3; Nuclear envelope spectrin repeat protein 3", "protein_names_refseq": "nesprin-3", "tax_id": 10116, "disease": "Huntington's disease (Disease Ontology:DOID:12858)", "pathway": " (rno:299356)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding;GO:0140444 cytoskeleton-nuclear membrane anchor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005640 nuclear outer membrane;GO:0034993 meiotic nuclear membrane microtubule tethering complex;GO:0005791 rough endoplasmic reticulum;GO:0005635 nuclear envelope", "go_biological_process": "GO:0007097 nuclear migration;GO:0007010 cytoskeleton organization;GO:0008360 regulation of cell shape;GO:0090150 establishment of protein localization to membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZD24-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K513-1", "uniprot_id": [ { "id": "A0A0G2K513_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K513", "type": "external" } ], "mass": 47025.0, "length": 418, "protein_name": "Transmembrane protein 143", "gene_name": "Tmem143", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tmem143", "gene_names_refseq": "", "protein_names_uniprotkb": "Transmembrane protein 143", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:308593)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0002244 hematopoietic progenitor cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K513-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5D7-1", "uniprot_id": [ { "id": "A0A0G2K5D7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5D7", "type": "external" } ], "mass": 117359.0, "length": 1058, "protein_name": "Sperm antigen with calponin homology and coiled-coil domains 1", "gene_name": "Specc1", "organism": "Rat", "refseq_name": "cytospin-B isoform 2", "refseq_ac": [ { "id": "NP_001415909", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001415909", "type": "external" } ], "gene_names_uniprotkb": "Specc1", "gene_names_refseq": "Cytsb; RGD1309718; Specc1", "protein_names_uniprotkb": "Sperm antigen with calponin homology and coiled-coil domains 1", "protein_names_refseq": "cytospin-B isoform 2; cytospin-B", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0045177 apical part of cell;GO:0005815 microtubule organizing center", "go_biological_process": "GO:0008306 associative learning;GO:0030036 actin cytoskeleton organization;GO:0001824 blastocyst development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K5D7-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5G5-1", "uniprot_id": [ { "id": "A0A0G2K5G5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5G5", "type": "external" } ], "mass": 32214.0, "length": 287, "protein_name": "DNA oxidative demethylase ALKBH2", "gene_name": "Alkbh2", "organism": "Rat", "refseq_name": "DNA oxidative demethylase ALKBH2 isoform X1", "refseq_ac": [ { "id": "XP_006249560", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006249560", "type": "external" } ], "gene_names_uniprotkb": "Alkbh2", "gene_names_refseq": "Alkbh2; RGD1306377", "protein_names_uniprotkb": "DNA oxidative demethylase ALKBH2; 1.14.11.33; Alkylated DNA repair protein alkB homolog 2; Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2", "protein_names_refseq": "DNA oxidative demethylase ALKBH2 isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.11.33", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.33", "type": "external" }, { "id": "1.14.11.51", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.51", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "1.14.11.54", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.54", "type": "external" } ], "go_molecular_function": "GO:0008198 ferrous iron binding;GO:0016706 2-oxoglutarate-dependent dioxygenase activity;GO:0051747 cytosine C-5 DNA demethylase activity;GO:0000182 rDNA binding;GO:0035516 broad specificity oxidative DNA demethylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0006307 DNA alkylation repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5G5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5V2-1", "uniprot_id": [ { "id": "A0A0G2K5V2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5V2", "type": "external" } ], "mass": 27282.0, "length": 238, "protein_name": "Y-linked testis-specific protein 1-like", "gene_name": "LOC134486221", "organism": "Rat", "refseq_name": "Y-linked testis-specific protein 1-like", "refseq_ac": [ { "id": "XP_063141214", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063141214", "type": "external" } ], "gene_names_uniprotkb": "LOC134486221; LOC134478817; LOC134480940; LOC134481117", "gene_names_refseq": "LOC134486221", "protein_names_uniprotkb": "Y-linked testis-specific protein 1-like", "protein_names_refseq": "Y-linked testis-specific protein 1-like", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0007276 gamete generation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5V2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5X7-1", "uniprot_id": [ { "id": "A0A0G2K5X7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5X7", "type": "external" } ], "mass": 15087.0, "length": 136, "protein_name": "Histone H3", "gene_name": "H3f3al3", "organism": "Rat", "refseq_name": "histone H3.3A-like", "refseq_ac": [ { "id": "XP_346042", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_346042", "type": "external" } ], "gene_names_uniprotkb": "H3f3al3; RGD1564447", "gene_names_refseq": "H3f3al3", "protein_names_uniprotkb": "Histone H3", "protein_names_refseq": "histone H3.3A-like", "tax_id": 10116, "disease": "", "pathway": " (rno:367254)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0031492 nucleosomal DNA binding;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0000776 kinetochore;GO:0043505 CENP-A containing nucleosome", "go_biological_process": "GO:0051382 kinetochore assembly;GO:0007080 mitotic metaphase chromosome alignment;GO:0031507 heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5X7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K604-1", "uniprot_id": [ { "id": "A0A0G2K604_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K604", "type": "external" } ], "mass": 30778.0, "length": 268, "protein_name": "RING-type domain-containing protein", "gene_name": "AABR07045341.1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07045341.1", "gene_names_refseq": "", "protein_names_uniprotkb": "RING-type domain-containing protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K604-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K618-1", "uniprot_id": [ { "id": "A0A0G2K618_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K618", "type": "external" } ], "mass": 87980.0, "length": 756, "protein_name": "LARGE xylosyl- and glucuronyltransferase 1", "gene_name": "Large1", "organism": "Rat", "refseq_name": "xylosyl- and glucuronyltransferase LARGE1", "refseq_ac": [ { "id": "NP_001416095", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001416095", "type": "external" } ], "gene_names_uniprotkb": "Large1", "gene_names_refseq": "Large1; Large", "protein_names_uniprotkb": "LARGE xylosyl- and glucuronyltransferase 1", "protein_names_refseq": "glycosyltransferase-like protein LARGE1; like-glycosyltransferase; xylosyl- and glucuronyltransferase LARGE1", "tax_id": 10116, "disease": "muscular dystrophy-dystroglycanopathy type B1 (Disease Ontology:DOID:0050588); muscular dystrophy-dystroglycanopathy type B6 (Disease Ontology:DOID:0110637); congenital muscular dystrophy-dystroglycanopathy type A6 (Disease Ontology:DOID:0111242); facioscapulohumeral muscular dystrophy (Disease Ontology:DOID:11727)", "pathway": " (rno:361368); (R-RNO-9939291)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.-", "type": "external" }, { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" }, { "id": "2.4.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.-.-", "type": "external" } ], "go_molecular_function": "GO:0042285 xylosyltransferase activity;GO:0030145 manganese ion binding;GO:0016757 glycosyltransferase activity;GO:0015020 glucuronosyltransferase activity;GO:0016758 hexosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0031594 neuromuscular junction;GO:0032991 protein-containing complex", "go_biological_process": "GO:0043403 skeletal muscle tissue regeneration;GO:0060538 skeletal muscle organ development;GO:0048708 astrocyte differentiation;GO:0006468 protein phosphorylation;GO:0006886 intracellular protein transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2K618-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K622-1", "uniprot_id": [ { "id": "A0A0G2K622_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K622", "type": "external" } ], "mass": 19739.0, "length": 169, "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "organism": "Rat", "refseq_name": "uncharacterized protein LOC100363294 isoform 1", "refseq_ac": [ { "id": "NP_001257345", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257345", "type": "external" } ], "gene_names_uniprotkb": "Slbpl; LOC100363294", "gene_names_refseq": "SLBP2; Slbpl", "protein_names_uniprotkb": "Histone RNA hairpin-binding protein; Histone stem-loop-binding protein", "protein_names_refseq": "stem loop binding protein 2; uncharacterized protein LOC100363294 isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:100363294)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "RNA-binding protein involved in the histone pre-mRNA processing. Binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to efficient 3'-end processing by stabilizing the complex between histone pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP), via the histone downstream element (HDE). Plays an important role in targeting mature histone mRNA from the nucleus to the cytoplasm and to the translation machinery. Stabilizes mature histone mRNA and could be involved in cell-cycle regulation of histone gene expression. Involved in the mechanism by which growing oocytes accumulate histone proteins that support early embryogenesis. Binds to the 5' side of the stem-loop structure of histone pre-mRNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0071207 histone pre-mRNA stem-loop binding;GO:0003729 mRNA binding", "go_cellular_component": "GO:0071204 histone pre-mRNA 3'end processing complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage;GO:0051028 mRNA transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K622-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K644-1", "uniprot_id": [ { "id": "A0A0G2K644_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K644", "type": "external" } ], "mass": 71528.0, "length": 644, "protein_name": "Synaptotagmin 16", "gene_name": "Syt16", "organism": "Rat", "refseq_name": "synaptotagmin 16 isoform 1", "refseq_ac": [ { "id": "NP_001415561", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001415561", "type": "external" } ], "gene_names_uniprotkb": "Syt16", "gene_names_refseq": "RGD1564654; Syt16", "protein_names_uniprotkb": "Synaptotagmin 16", "protein_names_refseq": "synaptotagmin 16 isoform 1; synaptotagmin XVI", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is Ca(2+)-independent., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0042802 identical protein binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K644-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K665-1", "uniprot_id": [ { "id": "A0A0G2K665_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K665", "type": "external" } ], "mass": 157602.0, "length": 1387, "protein_name": "GTPase activating protein testicular GAP1", "gene_name": "Tgap1", "organism": "Rat", "refseq_name": "GTPase activating protein testicular GAP1 isoform X1", "refseq_ac": [ { "id": "XP_038957885", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038957885", "type": "external" } ], "gene_names_uniprotkb": "Tgap1; Tgap1l11; tGap1", "gene_names_refseq": "Tgap1", "protein_names_uniprotkb": "GTPase activating protein testicular GAP1", "protein_names_refseq": "GTPase activating protein testicular GAP1 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:294892)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "", "go_biological_process": "GO:0007165 signal transduction;GO:0035023 regulation of Rho protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K665-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K6D5-1", "uniprot_id": [ { "id": "A0A0G2K6D5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K6D5", "type": "external" } ], "mass": 117421.0, "length": 1035, "protein_name": "Presequence protease, mitochondrial", "gene_name": "Pitrm1", "organism": "Rat", "refseq_name": "presequence protease, mitochondrial isoform 2", "refseq_ac": [ { "id": "NP_001402089", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001402089", "type": "external" } ], "gene_names_uniprotkb": "Pitrm1", "gene_names_refseq": "Pitrm1", "protein_names_uniprotkb": "Presequence protease, mitochondrial; Pitrilysin metalloproteinase 1", "protein_names_refseq": "pitrilysin metallepetidase 1; pitrilysin metalloprotease 1; presequence protease, mitochondrial isoform 2; presequence protease, mitochondrial", "tax_id": 10116, "disease": "hereditary ataxia (Disease Ontology:DOID:0050951); autosomal recessive spinocerebellar ataxia 30 (Disease Ontology:DOID:0070411); Alzheimer's disease (Disease Ontology:DOID:10652); primary cerebellar degeneration (Disease Ontology:DOID:9277)", "pathway": " (rno:307081); (R-RNO-1268020)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Metalloendopeptidase of the mitochondrial matrix that functions in peptide cleavage and degradation rather than in protein processing. Has an ATP-independent activity. Specifically cleaves peptides in the range of 5 to 65 residues. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference. Degrades the transit peptides of mitochondrial proteins after their cleavage. Also degrades other unstructured peptides. It is also able to degrade amyloid-beta protein 40, one of the peptides produced by APP processing, when it accumulates in mitochondrion. It is a highly efficient protease, at least toward amyloid-beta protein 40. Cleaves that peptide at a specific position and is probably not processive, releasing digested peptides intermediates that can be further cleaved subsequently. It is also able to degrade amyloid-beta protein 42., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008237 metallopeptidase activity;GO:0008270 zinc ion binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0051603 proteolysis involved in protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K6D5-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K6K2-1", "uniprot_id": [ { "id": "A0A0G2K6K2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K6K2", "type": "external" } ], "mass": 34386.0, "length": 308, "protein_name": "Olfactory receptor", "gene_name": "Or4b1", "organism": "Rat", "refseq_name": "olfactory receptor Olr741", "refseq_ac": [ { "id": "NP_001000575", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000575", "type": "external" } ], "gene_names_uniprotkb": "Or4b1", "gene_names_refseq": "Olr741; Or4b1", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 741; olfactory receptor Olr741-like; olfactory receptor Olr741; olfactory receptor gene Olr741", "tax_id": 10116, "disease": "oligoasthenoteratozoospermia (Disease Ontology:DOID:0070311)", "pathway": " (rno:366120)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0G2K8F8", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K6K2-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "uniprot_id": [ { "id": "A0A0G2K6V9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K6V9", "type": "external" } ], "mass": 55372.0, "length": 493, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2; Smokwl3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Smokwl2; Smokwl3; LOC134479633; LOC134479831; RGD1564409; RGD1565071; Smokwl3", "gene_names_refseq": "", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:314670); (rno:368175)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May play a role in sperm motility, especially in the regulation of flagellar function., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A0G2JZW9", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.4.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.18", "type": "external" }, { "id": "3.1.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.24.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0050321 tau-protein kinase activity;GO:0004674 protein serine/threonine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0000226 microtubule cytoskeleton organization;GO:0042149 cellular response to glucose starvation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K6V9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true 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"kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K754-1", "uniprot_id": [ { "id": "A0A0G2K754_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K754", "type": "external" } ], "mass": 107873.0, "length": 971, "protein_name": "Receptor-type tyrosine-protein phosphatase H", "gene_name": "Ptprh", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ptprh", "gene_names_refseq": "", "protein_names_uniprotkb": "Receptor-type tyrosine-protein phosphatase H; 2.7.10.1; 3.1.3.48; Stomach cancer-associated protein tyrosine phosphatase 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, 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Specifically recognizes and binds phosphorylated proteins via its SH2 domain, promoting their ubiquitination. The ECS(SOCS7) complex acts as a key regulator of reelin signaling by mediating ubiquitination and degradation of phosphorylated DAB1 in the cortical plate of the developing cerebral cortex, thereby regulating neuron positioning during cortex development. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Also inhibits prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035591 signaling adaptor activity;GO:1990756 ubiquitin-like ligase-substrate adaptor activity;GO:0140031 phosphorylation-dependent protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0031466 Cul5-RING ubiquitin ligase complex", "go_biological_process": "GO:0021799 cerebral cortex radially oriented cell migration;GO:0035556 intracellular signal transduction;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016567 protein ubiquitination;GO:0045444 fat cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K9S1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAC6-1", "uniprot_id": [ { "id": "A0A0G2KAC6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAC6", "type": "external" } ], "mass": 17703.0, "length": 173, "protein_name": "Keratin associated protein 1-3", "gene_name": "Krtap1-3", "organism": "Rat", "refseq_name": "keratin associated protein 1-3", "refseq_ac": [ { "id": "NP_001395601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001395601", "type": "external" } ], "gene_names_uniprotkb": "Krtap1-3", "gene_names_refseq": "Krtap1-3", "protein_names_uniprotkb": "Keratin associated protein 1-3", "protein_names_refseq": "keratin associated protein 1-3; keratin-associated protein 1-3-like; keratin-associated protein 9-3-like", "tax_id": 10116, "disease": "", "pathway": " (rno:680104); (R-RNO-6805567)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0045095 keratin filament", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KAC6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAH7-1", "uniprot_id": [ { "id": "A0A0G2KAH7_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7", "type": "external" } ], "mass": 90179.0, "length": 791, "protein_name": "Exostosin-2", "gene_name": "Ext2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ext2", "gene_names_refseq": "", "protein_names_uniprotkb": "Exostosin-2; 2.4.1.224; Exostosin glycosyltransferase 2; Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase", "protein_names_refseq": "", "tax_id": 10116, "disease": "hereditary multiple exostoses (Disease Ontology:DOID:206)", "pathway": " (rno:311215); (R-RNO-2022928)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Glycosyltransferase forming with EXT1 the heterodimeric heparan sulfate polymerase which catalyzes the elongation of the heparan sulfate glycan backbone. Glycan backbone extension consists in the alternating transfer of (1->4)-beta-D-GlcA and (1->4)-alpha-D-GlcNAc residues from their respective UDP-sugar donors. Both EXT1 and EXT2 are required for the full activity of the polymerase since EXT1 bears the N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity within the complex while EXT2 carries the glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity. Heparan sulfate proteoglycans are ubiquitous components of the extracellular matrix and play an important role in tissue homeostasis and signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.224", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.224", "type": "external" }, { "id": "2.4.1.225", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.225", "type": "external" } ], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0008375 acetylglucosaminyltransferase activity;GO:0016757 glycosyltransferase activity;GO:0015020 glucuronosyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0043541 UDP-N-acetylglucosamine transferase complex;GO:1902494 catalytic complex;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0051923 sulfation;GO:0000271 polysaccharide biosynthetic process;GO:0030154 cell differentiation;GO:0008217 regulation of blood pressure;GO:0042311 vasodilation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KAH7-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAI8-1", "uniprot_id": [ { "id": "A0A0G2KAI8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAI8", "type": "external" } ], "mass": 40371.0, "length": 364, "protein_name": "Developmentally regulated GTP binding protein 2", "gene_name": "Drg2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Drg2", "gene_names_refseq": "", "protein_names_uniprotkb": "Developmentally regulated GTP binding protein 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:497915)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KAI8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAL5-1", "uniprot_id": [ { "id": "A0A0G2KAL5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAL5", "type": "external" } ], "mass": 97464.0, "length": 857, "protein_name": "Vomeronasal 2 receptor 19 like 1", "gene_name": "Vom2r19l1", "organism": "Rat", "refseq_name": "vomeronasal type-2 receptor 116-like isoform X2", "refseq_ac": [ { "id": "XP_003748781", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003748781", "type": "external" } ], "gene_names_uniprotkb": "Vom2r19l1; LOC682419", "gene_names_refseq": "Vom2r19l1", "protein_names_uniprotkb": "Vomeronasal 2 receptor 19 like 1", "protein_names_refseq": "vomeronasal type-2 receptor 116-like isoform X2", "tax_id": 10116, "disease": "", "pathway": " (rno:682419)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KAL5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KAL6-1", "uniprot_id": [ { "id": "A0A0G2KAL6_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KAL6", "type": "external" } ], "mass": 42553.0, "length": 394, "protein_name": "Colony stimulating factor 2 receptor subunit alpha", "gene_name": "Csf2ra", "organism": "Rat", "refseq_name": "granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform X3", "refseq_ac": [ { "id": "XP_017454861", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017454861", "type": "external" } ], "gene_names_uniprotkb": "Csf2ra", "gene_names_refseq": "Csf2ra", "protein_names_uniprotkb": "Colony stimulating factor 2 receptor subunit alpha", "protein_names_refseq": "granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform X3", "tax_id": 10116, "disease": "pulmonary alveolar proteinosis (Disease Ontology:DOID:12120)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051916 granulocyte colony-stimulating factor binding;GO:0004902 granulocyte colony-stimulating factor receptor activity", "go_cellular_component": "GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0045471 response to ethanol;GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus;GO:0007259 cell surface receptor signaling pathway via JAK-STAT;GO:0070665 positive regulation of leukocyte proliferation;GO:0038157 granulocyte-macrophage colony-stimulating factor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KAL6-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KB00-1", "uniprot_id": [ { "id": "A0A0G2KB00_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KB00", "type": "external" } ], "mass": 242570.0, "length": 2167, "protein_name": "FRAS1-related extracellular matrix protein 1", "gene_name": "Frem1", "organism": "Rat", "refseq_name": "FRAS1-related extracellular matrix protein 1 precursor", "refseq_ac": [ { "id": "NP_001398464", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001398464", "type": "external" } ], "gene_names_uniprotkb": "Frem1", "gene_names_refseq": "Frem1; RGD1306981", "protein_names_uniprotkb": "FRAS1-related extracellular matrix protein 1; Protein QBRICK", "protein_names_refseq": "FRAS1-related extracellular matrix protein 1 precursor; FRAS1-related extracellular matrix protein 1", "tax_id": 10116, "disease": "chromosome 9p deletion syndrome (Disease Ontology:DOID:0060732); Fraser syndrome (Disease Ontology:DOID:0090001); congenital diaphragmatic hernia (Disease Ontology:DOID:3827)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "26382659", "class_list": "", "function": "Decreased expression of FREM1 in the nitrofen-induced congenital diaphragmatic hernia model may disturb the formation of the diaphragmatic mesenchyme, thus contributing to the development of diaphragmatic defects., [RefSeq, PubMed]; Extracellular matrix protein that plays a role in epidermal differentiation and is required for epidermal adhesion during embryonic development., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0016020 membrane;GO:0031012 extracellular matrix;GO:0005604 basement membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0097094 craniofacial suture morphogenesis;GO:0007160 cell-matrix adhesion;GO:0007154 cell communication;GO:0010669 epithelial structure maintenance;GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KB00-1", "record_type": "protein", "filter_code": "0000000.0000110.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KB96-1", "uniprot_id": [ { "id": "A0A0G2KB96_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KB96", "type": "external" } ], "mass": 135435.0, "length": 1239, "protein_name": "STIL, centriolar assembly protein", "gene_name": "Stil", "organism": "Rat", "refseq_name": "SCL-interrupting locus protein isoform X3", "refseq_ac": [ { "id": "XP_038967110", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038967110", "type": "external" } ], "gene_names_uniprotkb": "Stil", "gene_names_refseq": "Sil; Stil", "protein_names_uniprotkb": "STIL, centriolar assembly protein", "protein_names_refseq": "SCL-interrupting locus protein isoform X3", "tax_id": 10116, "disease": "primary autosomal recessive microcephaly 7 (Disease Ontology:DOID:0070278); microcephaly (Disease Ontology:DOID:10907)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005815 microtubule organizing center;GO:0005814 centriole;GO:0036064 ciliary basal body", "go_biological_process": "GO:0046601 positive regulation of centriole replication;GO:0000578 embryonic axis specification;GO:0001701 in utero embryonic development;GO:0030900 forebrain development;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KB96-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2KBB4-1", "uniprot_id": [ { "id": "A0A0G2KBB4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2KBB4", "type": "external" } ], "mass": 42338.0, "length": 369, "protein_name": "Sad1 and UNC84 domain containing 5", "gene_name": "Sun5", "organism": "Rat", "refseq_name": "SUN domain-containing protein 5", "refseq_ac": [ { "id": "NP_001402614", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001402614", "type": "external" } ], "gene_names_uniprotkb": "Sun5", "gene_names_refseq": "Spag4l; Sun5", "protein_names_uniprotkb": "Sad1 and UNC84 domain containing 5", "protein_names_refseq": "SUN domain-containing protein 5", "tax_id": 10116, "disease": "spermatogenic failure 16 (Disease Ontology:DOID:0070184)", "pathway": " (rno:296289)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043495 protein-membrane adaptor activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005637 nuclear inner membrane;GO:0034993 meiotic nuclear membrane microtubule tethering complex;GO:0120212 sperm head-tail coupling apparatus", "go_biological_process": "GO:0007283 spermatogenesis;GO:0007286 spermatid development;GO:0032880 regulation of protein localization;GO:0065003 protein-containing complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KBB4-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2QC33-1", "uniprot_id": [ { "id": "ATG4B_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2QC33", "type": "external" } ], "mass": 44364.0, "length": 393, "protein_name": "Cysteine protease ATG4B", "gene_name": "Atg4b", "organism": "Rat", "refseq_name": "cysteine protease ATG4B", "refseq_ac": [ { "id": "NP_001386126", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386126", "type": "external" } ], "gene_names_uniprotkb": "Atg4b", "gene_names_refseq": "Apg4b; Atg4b", "protein_names_uniprotkb": "Cysteine protease ATG4B; 3.4.22.-; Autophagy-related protein 4 homolog B", "protein_names_refseq": "ATG4 autophagy related 4 homolog B; autophagy-related 4B; autophagy-related protein 4 homolog B; cysteine protease ATG4B", "tax_id": 10116, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (rno:316640); (R-RNO-1632852)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "22673903;28633005", "class_list": "", "function": "Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins. Required for canonical autophagy (macroautophagy), non-canonical autophagy as well as for mitophagy. The protease activity is required for proteolytic activation of ATG8 family proteins: cleaves the C-terminal amino acid of ATG8 proteins MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Protease activity is also required to counteract formation of high-molecular weight conjugates of ATG8 proteins (ATG8ylation): acts as a deubiquitinating-like enzyme that removes ATG8 conjugated to other proteins, such as ATG3. In addition to the protease activity, also mediates delipidation of ATG8 family proteins. Catalyzes delipidation of PE-conjugated forms of ATG8 proteins during macroautophagy. Also involved in non-canonical autophagy, a parallel pathway involving conjugation of ATG8 proteins to single membranes at endolysosomal compartments, by catalyzing delipidation of ATG8 proteins conjugated to phosphatidylserine (PS). Compared to other members of the family (ATG4A, ATG4C or ATG4C), constitutes the major protein for proteolytic activation of ATG8 proteins, while it displays weaker delipidation activity than other ATG4 paralogs. Involved in phagophore growth during mitophagy independently of its protease activity and of ATG8 proteins: acts by regulating ATG9A trafficking to mitochondria and promoting phagophore-endoplasmic reticulum contacts during the lipid transfer phase of mitophagy., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "F1LRG2;Q4KM36", "ec_number_list": [ { "id": "3.4.22.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.-", "type": "external" } ], "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0097110 scaffold protein binding;GO:0008233 peptidase activity;GO:0004197 cysteine-type endopeptidase activity;GO:0008234 cysteine-type peptidase activity", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0006508 proteolysis;GO:0015031 protein transport;GO:0016485 protein processing;GO:0006914 autophagy", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2QC33-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140UHX3-1", "uniprot_id": [ { "id": "A0A140UHX3_RAT", "url": "https://www.uniprot.org/uniprot/A0A140UHX3", "type": "external" } ], "mass": 168778.0, "length": 1497, "protein_name": "Condensin-2 complex subunit D3", "gene_name": "Ncapd3", "organism": "Rat", "refseq_name": "condensin-2 complex subunit D3 isoform X1", "refseq_ac": [ { "id": "XP_006242797", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006242797", "type": "external" } ], "gene_names_uniprotkb": "Ncapd3", "gene_names_refseq": "Ncapd3", "protein_names_uniprotkb": "Condensin-2 complex subunit D3", "protein_names_refseq": "condensin-2 complex subunit D3 isoform X1", "tax_id": 10116, "disease": "primary autosomal recessive microcephaly 22 (Disease Ontology:DOID:0051033)", "pathway": " (R-RNO-2299718)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Specifically required for decatenation of centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042393 histone binding;GO:0140117 histone H4K20me1 reader activity", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005654 nucleoplasm;GO:0000793 condensed chromosome;GO:0000776 kinetochore;GO:0000796 condensin complex", "go_biological_process": "GO:1905820 positive regulation of chromosome separation;GO:0051984 positive regulation of chromosome segregation;GO:0051307 meiotic chromosome separation;GO:0051301 cell division;GO:0021987 cerebral cortex development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140UHX3-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWU0-1", "uniprot_id": [ { "id": "A0A1B0GWU0_RAT", "url": "https://www.uniprot.org/uniprot/A0A1B0GWU0", "type": "external" } ], "mass": 268384.0, "length": 2336, "protein_name": "Centriolin", "gene_name": "Cntrl", "organism": "Rat", "refseq_name": "centriolin", "refseq_ac": [ { "id": "NP_001414108", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414108", "type": "external" } ], "gene_names_uniprotkb": "Cntrl", "gene_names_refseq": "Cep110; Cep1; Cntrl", "protein_names_uniprotkb": "Centriolin; Centrosomal protein 1; Centrosomal protein of 110 kDa", "protein_names_refseq": "centriolin; centrosomal protein 110kDa; centrosomal protein 110; centrosomal protein 1", "tax_id": 10116, "disease": "nephronophthisis (Disease Ontology:DOID:12712)", "pathway": " (rno:311886)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in cell cycle progression and cytokinesis. During the late steps of cytokinesis, anchors exocyst and SNARE complexes at the midbody, thereby allowing secretory vesicle-mediated abscission., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0090619 meiotic spindle pole;GO:0005813 centrosome;GO:0048471 perinuclear region of cytoplasm;GO:0090543 Flemming body;GO:0072687 meiotic spindle", "go_biological_process": "GO:0051301 cell division;GO:0001822 kidney development;GO:0003281 ventricular septum development;GO:0035904 aorta development;GO:0060976 coronary vasculature development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1B0GWU0-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1B0GWX7-1", "uniprot_id": [ { "id": "A0A1B0GWX7_RAT", "url": "https://www.uniprot.org/uniprot/A0A1B0GWX7", "type": "external" } ], "mass": 40301.0, "length": 351, "protein_name": "V-type proton ATPase subunit", "gene_name": "Atp6v0d1", "organism": "Rat", "refseq_name": "V-type proton ATPase subunit d 1", "refseq_ac": [ { "id": "NP_001011927", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011927", "type": "external" } ], "gene_names_uniprotkb": "Atp6v0d1", "gene_names_refseq": "Ac39; Atp6v0d1", "protein_names_uniprotkb": "V-type proton ATPase subunit", "protein_names_refseq": "ATPase, H+ transporting, V0 subunit D; ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1; ATPase, H+ transporting, lysosomal V0 subunit D1; V-type proton ATPase subunit d 1; physophilin", "tax_id": 10116, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); lipodystrophy (Disease Ontology:DOID:811)", "pathway": " (rno:291969); (R-RNO-1222556); (R-RNO-77387); (R-RNO-917977); (R-RNO-9639288); (R-RNO-983712)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046961 proton-transporting ATPase activity, rotational mechanism;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0033179 proton-transporting V-type ATPase, V0 domain;GO:0033176 proton-transporting V-type ATPase complex;GO:0005769 early endosome;GO:0005813 centrosome;GO:0016020 membrane", "go_biological_process": "GO:0007034 vacuolar transport;GO:0006879 intracellular iron ion homeostasis;GO:0036295 cellular response to increased oxygen levels;GO:0097401 synaptic vesicle lumen acidification;GO:0007035 vacuolar acidification", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1B0GWX7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1W2Q660-1", "uniprot_id": [ { "id": "A0A1W2Q660_RAT", "url": "https://www.uniprot.org/uniprot/A0A1W2Q660", "type": "external" } ], "mass": 55402.0, "length": 486, "protein_name": "Septin 14", "gene_name": "Septin14", "organism": "Rat", "refseq_name": "septin-14 isoform X1", "refseq_ac": [ { "id": "XP_038945695", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038945695", "type": "external" } ], "gene_names_uniprotkb": "Septin14; Sept14", "gene_names_refseq": "Sept14; Septin14", "protein_names_uniprotkb": "Septin 14", "protein_names_refseq": "septin-14 isoform X1", "tax_id": 10116, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (rno:689118)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005940 septin ring;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0030424 axon;GO:0030425 dendrite", "go_biological_process": "GO:0001764 neuron migration;GO:0007286 spermatid development;GO:0008104 intracellular protein localization;GO:1905719 protein localization to perinuclear region of cytoplasm;GO:0061640 cytoskeleton-dependent cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1W2Q660-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B2GUX7-1", "uniprot_id": [ { "id": "B2GUX7_RAT", "url": "https://www.uniprot.org/uniprot/B2GUX7", "type": "external" } ], "mass": 37446.0, "length": 335, "protein_name": "Cellular repressor of E1A-stimulated genes 1", "gene_name": "Creg1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Creg1", "gene_names_refseq": "", "protein_names_uniprotkb": "Cellular repressor of E1A-stimulated genes 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:289185); (R-RNO-6798695)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005159 insulin-like growth factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005768 endosome;GO:0005764 lysosome;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006897 endocytosis;GO:0006355 regulation of DNA-templated transcription;GO:0006914 autophagy;GO:0007040 lysosome organization;GO:0007042 lysosomal lumen acidification", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B2GUX7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z7Y1-1", "uniprot_id": [ { "id": "D3Z7Y1_RAT", "url": "https://www.uniprot.org/uniprot/D3Z7Y1", "type": "external" } ], "mass": 34465.0, "length": 300, "protein_name": "unspecific monooxygenase", "gene_name": "AABR07004560.1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07004560.1", "gene_names_refseq": "", "protein_names_uniprotkb": "unspecific monooxygenase; 1.14.14.1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z7Y1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z8A8-1", "uniprot_id": [ { "id": "D3Z8A8_RAT", "url": "https://www.uniprot.org/uniprot/D3Z8A8", "type": "external" } ], "mass": 44941.0, "length": 396, "protein_name": "Meiotic recombination protein SPO11", "gene_name": "Spo11", "organism": "Rat", "refseq_name": "meiotic recombination protein SPO11", "refseq_ac": [ { "id": "NP_001402745", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001402745", "type": "external" } ], "gene_names_uniprotkb": "Spo11", "gene_names_refseq": "Spo11", "protein_names_uniprotkb": "Meiotic recombination protein SPO11; 5.6.2.2", "protein_names_refseq": "SPO11 meiotic protein covalently bound to DSB homolog; SPO11, initiator of meiotic double stranded breaks; meiotic recombination protein SPO11; sporulation protein, meiosis-specific, SPO11 homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:366261)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity;GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0000228 nuclear chromosome;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0007286 spermatid development;GO:0001541 ovarian follicle development;GO:0007130 synaptonemal complex assembly;GO:0048477 oogenesis;GO:0007129 homologous chromosome pairing at meiosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z8A8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z8B2-1", "uniprot_id": [ { "id": "D3Z8B2_RAT", "url": "https://www.uniprot.org/uniprot/D3Z8B2", "type": "external" } ], "mass": 128360.0, "length": 1154, "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "Nup133", "organism": "Rat", "refseq_name": "nuclear pore complex protein Nup133", "refseq_ac": [ { "id": "NP_001387884", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001387884", "type": "external" } ], "gene_names_uniprotkb": "Nup133", "gene_names_refseq": "Nup133", "protein_names_uniprotkb": "Nuclear pore complex protein Nup133; 133 kDa nucleoporin; Nucleoporin Nup133", "protein_names_refseq": "nuclear pore complex protein Nup133", "tax_id": 10116, "disease": "Galloway-Mowat syndrome 1 (Disease Ontology:DOID:0060364); nephrotic syndrome type 18 (Disease Ontology:DOID:0080393); Galloway-Mowat syndrome (Disease Ontology:DOID:0080694)", "pathway": " (rno:292085); (R-RNO-141430); (R-RNO-141444); (R-RNO-159227); (R-RNO-159230); (R-RNO-159231); (R-RNO-159236); (R-RNO-170822); (R-RNO-1855170); (R-RNO-1855196); (R-RNO-1855229); (R-RNO-191859); (R-RNO-2467813); (R-RNO-2500257); (R-RNO-3108214); (R-RNO-3232142); (R-RNO-3301854); (R-RNO-3371453); (R-RNO-4085377); (R-RNO-4551638); (R-RNO-4570464); (R-RNO-4615885); (R-RNO-5663220); (R-RNO-68877); (R-RNO-9615933); (R-RNO-9648025)", "pathway_count": 26, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Involved in poly(A)+ RNA transport. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"uniprot_canonical_ac": "F1M4C6-1", "uniprot_id": [ { "id": "F1M4C6_RAT", "url": "https://www.uniprot.org/uniprot/F1M4C6", "type": "external" } ], "mass": 26332.0, "length": 226, "protein_name": "Disks large homolog 5 N-terminal domain-containing protein", "gene_name": "Dlg5l1; ENSRNOG00000065746; LOC134478811; LOC134483146; LOC134483259; LOC134483277; LOC134483408", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Dlg5l1; ENSRNOG00000065746; LOC134478811; LOC134483146; LOC134483259; LOC134483277; LOC134483408; Dlg5l10; Dlg5l15; Dlg5l1; Dlg5l4; LOC100363225; LOC134478811; LOC134478848; LOC134478878; LOC134478901; LOC134478916; LOC134483122; LOC134483126; LOC134483128; LOC134483129; LOC134483130; LOC134483131; LOC134483132; LOC134483133; LOC134483136; LOC134483139; LOC134483140; LOC134483142; LOC134483144; LOC134483146; LOC134483151; LOC134483152; LOC134483153; LOC134483154; LOC134483163; LOC134483169; LOC134483170; LOC134483173; LOC134483175; LOC134483178; LOC134483185; LOC134483186; LOC134483187; LOC134483188; LOC134483193; LOC134483199; LOC134483202; LOC134483205; LOC134483207; LOC134483208; LOC134483209; LOC134483210; LOC134483212; LOC134483215; LOC134483222; LOC134483223; LOC134483224; LOC134483225; LOC134483226; LOC134483232; LOC134483233; LOC134483235; LOC134483239; LOC134483240; LOC134483241; LOC134483246; LOC134483259; LOC134483260; LOC134483261; LOC134483262; LOC134483263; LOC134483264; LOC134483265; LOC134483266; LOC134483270; LOC134483276; LOC134483277; LOC134483281; LOC134483284; LOC134483288; LOC134483290; LOC134483306; LOC134483307; LOC134483308; LOC134483309; LOC134483341; LOC134483342; LOC134483381; LOC134483383; LOC134483398; LOC134483420; LOC134483422; LOC134483427; LOC134483430; LOC134483435; LOC134483446; LOC134483458; LOC134483459; LOC134483470; LOC134483492; LOC134483494; LOC134483525; LOC134483533; LOC134483543; LOC134483547; LOC134483548; LOC134483551; LOC134483552; LOC134483554; LOC134483566; 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import into nucleus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZH55-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZV81-1", "uniprot_id": [ { "id": "D3ZV81_RAT", "url": "https://www.uniprot.org/uniprot/D3ZV81", "type": "external" } ], "mass": 74789.0, "length": 682, "protein_name": "HEAT repeat-containing protein 3", "gene_name": "Heatr3", "organism": "Rat", "refseq_name": "HEAT repeat-containing protein 3", "refseq_ac": [ { "id": "XP_341655", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_341655", "type": "external" } ], "gene_names_uniprotkb": "Heatr3", "gene_names_refseq": "Heatr3", "protein_names_uniprotkb": "HEAT repeat-containing protein 3; Symportin Syo1", "protein_names_refseq": "HEAT repeat-containing protein 3", "tax_id": 10116, "disease": "Diamond-Blackfan anemia (Disease Ontology:DOID:1339)", "pathway": " (rno:361375)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "Plays a role in ribosome biogenesis and in nuclear import of the 60S ribosomal protein L5/large ribosomal subunit protein uL18 (RPL5). Required for proper erythrocyte maturation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0043249 erythrocyte maturation;GO:0042273 ribosomal large subunit biogenesis;GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZV81-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LW58-1", "uniprot_id": [ { "id": "F1LW58_RAT", "url": "https://www.uniprot.org/uniprot/F1LW58", "type": "external" } ], "mass": 48221.0, "length": 429, "protein_name": "Chordin-like 2", "gene_name": "Chrdl2", "organism": "Rat", "refseq_name": "chordin-like protein 2 precursor", "refseq_ac": [ { "id": "NP_001101007", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101007", "type": "external" } ], "gene_names_uniprotkb": "Chrdl2", "gene_names_refseq": "Chrdl2", "protein_names_uniprotkb": "Chordin-like 2", "protein_names_refseq": "chordin-like protein 2 precursor; 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Mediates the autocatalytic cleavage that releases the Myelin regulatory factor, N-terminal component that specifically activates transcription of central nervous system (CNS) myelin genes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Membrane-bound part that has no transcription factor activity and remains attached to the endoplasmic reticulum membrane following cleavage., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Transcription factor that specifically activates expression of myelin genes such as MBP, MOG, MAG, DUSP15 and PLP1 during oligodendrocyte (OL) maturation, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Specifically recognizes and binds DNA sequence 5'-CTGGYAC-3' in the regulatory regions of myelin-specific genes and directly activates their expression. Not only required during oligodendrocyte differentiation but is also required on an ongoing basis for the maintenance of expression of myelin genes and for the maintenance of a mature, viable oligodendrocyte phenotype., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008233 peptidase activity;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005789 endoplasmic reticulum membrane;GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0016540 protein autoprocessing;GO:0006357 regulation of transcription by RNA polymerase II;GO:0022010 central nervous system myelination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A352-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZHD1-1", "uniprot_id": [ { "id": "D3ZHD1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZHD1", "type": "external" } ], "mass": 36129.0, "length": 319, "protein_name": "Annexin", "gene_name": "Anxa13", "organism": "Rat", "refseq_name": "annexin A13", "refseq_ac": [ { "id": "NP_001128382", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128382", "type": "external" } ], "gene_names_uniprotkb": "Anxa13", "gene_names_refseq": "Anxa13", "protein_names_uniprotkb": "Annexin", "protein_names_refseq": "annexin A13", "tax_id": 10116, "disease": "", "pathway": " (rno:362915)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binds to membranes enriched in phosphatidylserine or phosphatidylglycerol in a calcium-dependent manner. Half-maximal membrane binding requires about 60 uM calcium. Does not bind to membranes that lack phospholipids with an acidic headgroup., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005544 calcium-dependent phospholipid binding;GO:0001786 phosphatidylserine binding;GO:1901611 phosphatidylglycerol binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0042998 positive regulation of Golgi to plasma membrane protein transport;GO:0042997 negative regulation of Golgi to plasma membrane protein transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZHD1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZN31-1", "uniprot_id": [ { "id": "D3ZN31_RAT", "url": "https://www.uniprot.org/uniprot/D3ZN31", "type": "external" } ], "mass": 54531.0, "length": 501, "protein_name": "SH2 domain containing adaptor protein B", "gene_name": "Shb", "organism": "Rat", "refseq_name": "SH2 domain-containing adapter protein B", "refseq_ac": [ { "id": "NP_001414327", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414327", "type": "external" } ], "gene_names_uniprotkb": "Shb", "gene_names_refseq": "RGD1565350; Shb", "protein_names_uniprotkb": "SH2 domain containing adaptor protein B", "protein_names_refseq": "SH2 domain-containing adapter protein B; Src homology 2 domain containing adaptor protein B", "tax_id": 10116, "disease": "", "pathway": " (rno:362513); (R-RNO-4420097)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001784 phosphotyrosine residue binding;GO:0030159 signaling receptor complex adaptor activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0045931 positive regulation of mitotic cell cycle;GO:0006469 negative regulation of protein kinase activity;GO:0006915 apoptotic process;GO:0050852 T cell receptor signaling pathway;GO:0048514 blood vessel morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZN31-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ACT3-1", "uniprot_id": [ { "id": "D4ACT3_RAT", "url": "https://www.uniprot.org/uniprot/D4ACT3", "type": "external" } ], "mass": 55501.0, "length": 479, "protein_name": "PRAME family member 8-like", "gene_name": "LOC134481897", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC134481897; LOC120096511", "gene_names_refseq": "", "protein_names_uniprotkb": "PRAME family member 8-like", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:134481897)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031462 Cul2-RING ubiquitin ligase complex", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0045892 negative regulation of DNA-templated transcription;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045596 negative regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ACT3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AA14-1", "uniprot_id": [ { "id": "D4AA14_RAT", "url": "https://www.uniprot.org/uniprot/D4AA14", "type": "external" } ], "mass": 44065.0, "length": 403, "protein_name": "Ferroptosis suppressor protein 1", "gene_name": "Aifm2", "organism": "Rat", "refseq_name": "ferroptosis suppressor protein 1 isoform X2", "refseq_ac": [ { "id": "XP_006256515", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006256515", "type": "external" } ], "gene_names_uniprotkb": "Aifm2", "gene_names_refseq": "Aifm2; Amid; Prg3", "protein_names_uniprotkb": "Ferroptosis suppressor protein 1; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; p53-responsive gene 3 protein", "protein_names_refseq": "ferroptosis suppressor protein 1 isoform X2", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.5.2", "type": "external" } ], "go_molecular_function": "GO:0016491 oxidoreductase activity;GO:0003677 DNA binding;GO:0050660 flavin adenine dinucleotide binding;GO:0004174 electron-transferring-flavoprotein dehydrogenase activity;GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005811 lipid droplet", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0008637 apoptotic mitochondrial changes;GO:1900407 regulation of cellular response to oxidative stress;GO:0042373 vitamin K metabolic process;GO:0006743 ubiquinone metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AA14-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AE17-1", "uniprot_id": [ { "id": "D4AE17_RAT", "url": "https://www.uniprot.org/uniprot/D4AE17", "type": "external" } ], "mass": 91698.0, "length": 802, "protein_name": "Mitogen-activated protein kinase kinase kinase 20", "gene_name": "Map3k20", "organism": "Rat", "refseq_name": "mitogen-activated protein kinase kinase kinase 20 isoform 1", "refseq_ac": [ { "id": "NP_001385922", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385922", "type": "external" } ], "gene_names_uniprotkb": "Map3k20; Zak", "gene_names_refseq": "MLTK; Map3k20; RGD1561394; Zak", "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase 20; 2.7.11.25; Leucine zipper- and sterile alpha motif-containing kinase; MLK-like mitogen-activated protein triple kinase; Mitogen-activated protein kinase kinase kinase MLT; Mixed lineage kinase-related kinase; Sterile alpha motif- and leucine zipper-containing kinase AZK", "protein_names_refseq": "mitogen-activated protein kinase kinase kinase 20 isoform 1; mitogen-activated protein kinase kinase kinase MLT; sterile alpha motif and leucine zipper containing kinase AZK", "tax_id": 10116, "disease": "split hand-foot malformation (Disease Ontology:DOID:0090020); centronuclear myopathy 6 with fiber-type disproportion (Disease Ontology:DOID:0111221)", "pathway": " (rno:311743)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "19184368;22673903;25869677", "class_list": "", "function": "Isoform that lacks the C-terminal region that mediates ribosome-binding: does not act as a sensor of ribosome collisions in response to ribotoxic stress. May act as an antagonist of isoform ZAKalpha: interacts with isoform ZAKalpha, leading to decrease the expression of isoform ZAKalpha., [UniProtKB, UniProtKB]; Stress-activated component of a protein kinase signal transduction cascade that promotes programmed cell death in response to various stress, such as ribosomal stress, osmotic shock and ionizing radiation. Acts by catalyzing phosphorylation of MAP kinase kinases, leading to activation of the JNK (MAPK8/JNK1, MAPK9/JNK2 and/or MAPK10/JNK3) and MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) pathways. Activates JNK through phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7, and MAP kinase p38 gamma (MAPK12) via phosphorylation of MAP2K3/MKK3 and MAP2K6/MKK6. Involved in stress associated with adrenergic stimulation: contributes to cardiac decompensation during periods of acute cardiac stress. May be involved in regulation of S and G2 cell cycle checkpoint by mediating phosphorylation of CHEK2., [UniProtKB, UniProtKB]; The role of ZAK and/or the ZAK downstream events such as JNK and p38 phosphorylation, c-Jun, and GATA-4 nuclear translocation in cardiac hypertrophy., [RefSeq, PubMed]; ZAK activity inhibition may be a good strategy to prevent the cardiac fibrosis progression., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, 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"https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.4.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.18", "type": "external" }, { "id": "3.1.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.24.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0000287 magnesium ion binding;GO:0004674 protein serine/threonine kinase activity;GO:0030295 protein kinase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0071493 cellular response to UV-B;GO:0006468 protein phosphorylation;GO:0006954 inflammatory response;GO:0035556 intracellular signal transduction;GO:0043065 positive regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D4AE17-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M1F1-1", "uniprot_id": [ { "id": "F1M1F1_RAT", "url": "https://www.uniprot.org/uniprot/F1M1F1", "type": "external" } ], "mass": 102877.0, "length": 914, "protein_name": "E3 ubiquitin-protein ligase MARCHF6", "gene_name": "Marchf6", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase MARCHF6 isoform X1", "refseq_ac": [ { "id": "XP_008759048", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008759048", "type": "external" } ], "gene_names_uniprotkb": "Marchf6; March6", "gene_names_refseq": "March6; Marchf6; RGD1310927; RGD1565757", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase MARCHF6; 2.3.2.27; Membrane-associated RING finger protein 6; Membrane-associated RING-CH protein VI", "protein_names_refseq": "E3 ubiquitin-protein ligase MARCHF6 isoform X1", "tax_id": 10116, "disease": "familial adult myoclonic epilepsy 3 (Disease Ontology:DOID:0111695)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, 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In vitro, inhibits DNA-binding activity of Mad-MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. 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"type": "external" }, { "id": "3.1.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.24.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0052810 1-phosphatidylinositol-5-kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0031902 late endosome membrane;GO:0030670 phagocytic vesicle membrane;GO:0031901 early endosome membrane;GO:0005829 cytosol", "go_biological_process": "GO:0035556 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"reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005813 centrosome;GO:0034451 centriolar satellite", "go_biological_process": "GO:0021987 cerebral cortex development;GO:0045664 regulation of neuron differentiation;GO:0022008 neurogenesis;GO:0002052 positive regulation of neuroblast proliferation;GO:0046605 regulation of centrosome cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1M5K2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZYV3-1", "uniprot_id": [ { "id": "D3ZYV3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZYV3", "type": "external" } ], "mass": 38443.0, "length": 348, "protein_name": "Peptidoglycan recognition protein 3-like", "gene_name": "Pglyrp3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Pglyrp3; LOC134485743", "gene_names_refseq": "", "protein_names_uniprotkb": "Peptidoglycan recognition protein 3-like", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-6803157)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Also binds to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1M4E6", "ec_number_list": [], "go_molecular_function": "GO:0008745 N-acetylmuramoyl-L-alanine amidase activity;GO:0008270 zinc ion binding;GO:0042834 peptidoglycan binding;GO:0046982 protein heterodimerization activity;GO:0016019 peptidoglycan immune receptor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0032991 protein-containing complex", "go_biological_process": "GO:0002376 immune system process;GO:0009253 peptidoglycan catabolic process;GO:0051239 regulation of multicellular organismal process;GO:0032827 negative regulation of natural killer cell differentiation involved in immune response;GO:0006955 immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZYV3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A0U9-1", "uniprot_id": [ { "id": "D4A0U9_RAT", "url": "https://www.uniprot.org/uniprot/D4A0U9", "type": "external" } ], "mass": 159493.0, "length": 1441, "protein_name": "DNA mismatch repair protein", "gene_name": "Msh6", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Msh6", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA mismatch repair protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "hereditary nonpolyposis colorectal cancer type 5 (Disease Ontology:DOID:0070272); colorectal carcinoma (Disease Ontology:DOID:0080199); mismatch repair cancer syndrome (Disease Ontology:DOID:0112182); urinary bladder cancer (Disease Ontology:DOID:11054); endometrial cancer (Disease Ontology:DOID:1380); breast cancer (Disease Ontology:DOID:1612); ovarian cancer (Disease Ontology:DOID:2394); osteosarcoma (Disease Ontology:DOID:3347); breast carcinoma (Disease Ontology:DOID:3459); Lynch syndrome (Disease Ontology:DOID:3883); primary ovarian insufficiency (Disease Ontology:DOID:5426)", "pathway": " (R-RNO-5358565)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Component of the post-replicative DNA mismatch repair system (MMR)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0030983 mismatched DNA binding;GO:0140664 ATP-dependent DNA damage sensor activity;GO:0032357 oxidized purine DNA binding;GO:0032142 single guanine insertion binding", "go_cellular_component": "GO:0032301 MutSalpha complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0006298 mismatch repair;GO:0006281 DNA repair;GO:0007283 spermatogenesis;GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage;GO:0009411 response to UV", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A0U9-1", "record_type": "protein", "filter_code": "0000000.1000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZER4-1", "uniprot_id": [ { "id": "D3ZER4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZER4", "type": "external" } ], "mass": 84884.0, "length": 783, "protein_name": "Denticleless protein homolog", "gene_name": "Dtl", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Dtl", "gene_names_refseq": "", "protein_names_uniprotkb": "Denticleless protein homolog; Lethal(2) denticleless protein homolog; Retinoic acid-regulated nuclear matrix-associated protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-110314); (R-RNO-8951664)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0031464 Cul4A-RING E3 ubiquitin ligase complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005813 centrosome;GO:0031965 nuclear membrane", "go_biological_process": "GO:0010971 positive regulation of G2/M transition of mitotic cell cycle;GO:0006974 DNA damage response;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0009411 response to UV;GO:0048511 rhythmic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZER4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZEX3-1", "uniprot_id": [ { "id": "D3ZEX3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZEX3", "type": "external" } ], "mass": 20739.0, "length": 181, "protein_name": "Trafficking protein particle complex subunit", "gene_name": "Trappc3l", "organism": "Rat", "refseq_name": "trafficking protein particle complex subunit 3L", "refseq_ac": [ { "id": "NP_001419413", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001419413", "type": "external" } ], "gene_names_uniprotkb": "Trappc3l; Bet3l", "gene_names_refseq": "Bet3l; Trappc3l", "protein_names_uniprotkb": "Trafficking protein particle complex subunit", "protein_names_refseq": "BET3 like; trafficking protein particle complex 3-like; trafficking protein particle complex subunit 3L", "tax_id": 10116, "disease": "", "pathway": " (rno:100362279)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May play a role in vesicular transport from endoplasmic reticulum to Golgi., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0033106 cis-Golgi network membrane;GO:0030008 TRAPP complex;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006891 intra-Golgi vesicle-mediated transport;GO:0048193 Golgi vesicle transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZEX3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZF32-1", "uniprot_id": [ { "id": "D3ZF32_RAT", "url": "https://www.uniprot.org/uniprot/D3ZF32", "type": "external" } ], "mass": 37214.0, "length": 330, "protein_name": "Trem-like transcript 2 protein", "gene_name": "Treml2", "organism": "Rat", "refseq_name": "triggering receptor expressed on myeloid cells-like 2 precursor", "refseq_ac": [ { "id": "NP_001420259", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001420259", "type": "external" } ], "gene_names_uniprotkb": "Treml2", "gene_names_refseq": "Treml2", "protein_names_uniprotkb": "Trem-like transcript 2 protein; Triggering receptor expressed on myeloid cells-like protein 2", "protein_names_refseq": "triggering receptor expressed on myeloid cells-like 2 precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:680844); (R-RNO-198933)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cell surface receptor that may play a role in the innate and adaptive immune response. 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"pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0045095 keratin filament", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZGB2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZGE3-1", "uniprot_id": [ { "id": "D3ZGE3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZGE3", "type": "external" } ], "mass": 35214.0, "length": 311, "protein_name": "Olfactory receptor", "gene_name": "Or4c110", "organism": "Rat", "refseq_name": "olfactory receptor Olr670", "refseq_ac": [ { "id": "NP_001000633", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000633", "type": "external" } ], "gene_names_uniprotkb": "Or4c110", "gene_names_refseq": "Olr670; Or4c110", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 670; olfactory receptor Olr670; olfactory receptor gene Olr670", "tax_id": 10116, "disease": "", "pathway": " (rno:404826)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZGE3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZGF0-1", "uniprot_id": [ { "id": "D3ZGF0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZGF0", "type": "external" } ], "mass": 35166.0, "length": 310, "protein_name": "Olfactory receptor", "gene_name": "Or4c35", "organism": "Rat", "refseq_name": "olfactory receptor Olr725", "refseq_ac": [ { "id": "NP_001000514", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000514", "type": "external" } ], "gene_names_uniprotkb": "Or4c35", "gene_names_refseq": "Olr725; Or4c35", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 725; olfactory receptor Olr725; olfactory receptor gene Olr725", "tax_id": 10116, "disease": "", "pathway": " (rno:311180)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZGF0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZGN9-1", "uniprot_id": [ { "id": "D3ZGN9_RAT", "url": "https://www.uniprot.org/uniprot/D3ZGN9", "type": "external" } ], "mass": 34978.0, "length": 314, "protein_name": "Olfactory receptor", "gene_name": "Or51f4", "organism": "Rat", "refseq_name": "olfactory receptor Olr53", "refseq_ac": [ { "id": "NP_001001008", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001008", "type": "external" } ], "gene_names_uniprotkb": "Or51f4", "gene_names_refseq": "Olr53; Or51f4", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 53; olfactory receptor Olr53; olfactory receptor gene Olr53", "tax_id": 10116, "disease": "", "pathway": " (rno:405378)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0071396 cellular response to lipid", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZGN9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZGT4-1", "uniprot_id": [ { "id": "D3ZGT4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZGT4", "type": "external" } ], "mass": 9930.0, "length": 79, "protein_name": "Cyclin-dependent kinases regulatory subunit", "gene_name": "LOC120102505", "organism": "Rat", "refseq_name": "cyclin-dependent kinases regulatory subunit 2-like", "refseq_ac": [ { "id": "XP_038964963", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038964963", "type": "external" } ], "gene_names_uniprotkb": "LOC120102505", "gene_names_refseq": "LOC120102505", "protein_names_uniprotkb": "Cyclin-dependent kinases regulatory subunit", "protein_names_refseq": "cyclin-dependent kinases regulatory subunit 2-like", "tax_id": 10116, "disease": "", "pathway": " (rno:120102505)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0042393 histone binding;GO:0043130 ubiquitin binding;GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity", "go_cellular_component": "GO:0019005 SCF ubiquitin ligase complex;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:0044772 mitotic cell cycle phase transition;GO:0051301 cell division;GO:0007346 regulation of mitotic cell cycle;GO:0048144 fibroblast proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZGT4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZGZ6-1", "uniprot_id": [ { "id": "DESPR_RAT", "url": "https://www.uniprot.org/uniprot/D3ZGZ6", "type": "external" } ], "mass": 13733.0, "length": 127, "protein_name": "Dual endothelin-1/VEGF signal peptide receptor", "gene_name": "Fbxw7-as1", "organism": "Rat", "refseq_name": "dual endothelin-1/VEGF signal peptide receptor", "refseq_ac": [ { "id": "NP_001004448", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004448", "type": "external" } ], "gene_names_uniprotkb": "Fbxw7-as1; Dear", "gene_names_refseq": "DEspR; Dear; Fbxw7-as1", "protein_names_uniprotkb": "Dual endothelin-1/VEGF signal peptide receptor; DEspR protein; Dear protein; Dual endothelin-1/VEGFsp receptor; Dual endothelin-1/angiotensin-2 receptor; FBXW7 antisense RNA 1 homolog", "protein_names_refseq": "FBXW7 antisense RNA 1 homolog; dual endothelin-1/VEGF signal peptide receptor; dual endothelin-1/VEGFsp receptor; dual endothelin-1/angiotensin-2 receptor", "tax_id": 10116, "disease": "", "pathway": " (rno:446170)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15561758;9508787", "class_list": "", "function": "In the Dahl salt-resistant strain, acts as a dual receptor for both endothelin-1 and the signal sequence of vascular endothelial growth factor A and does not act as a receptor for angiotensin-2 (PubMed:15561758). Does not bind the VEGFA mature protein (By similarity). In the Dahl salt-sensitive strain, acts as a dual endothelin-1/angiotensin-2 receptor that is functionally coupled to a calcium-mobilizing transduction system, responding equivalently to both endothelin-1/EDN1 and angiotensin-2 peptides in a highly specific manner (PubMed:15561758, PubMed:9508787). May play a role in angiogenesis with a significant role in cardiovascular and neural development (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6BDA5", "ec_number_list": [], "go_molecular_function": "GO:0004962 endothelin receptor activity;GO:0004945 angiotensin type II receptor activity;GO:0038085 vascular endothelial growth factor binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0086100 endothelin receptor signaling pathway;GO:0007186 G protein-coupled receptor signaling pathway;GO:0038084 vascular endothelial growth factor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZGZ6-1", "record_type": "protein", "filter_code": "0000000.0100101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZH90-1", "uniprot_id": [ { "id": "D3ZH90_RAT", "url": "https://www.uniprot.org/uniprot/D3ZH90", "type": "external" } ], "mass": 24106.0, "length": 211, "protein_name": "Nucleoside diphosphate kinase 5", "gene_name": "Nme5", "organism": "Rat", "refseq_name": "nucleoside diphosphate kinase homolog 5", "refseq_ac": [ { "id": "NP_001414325", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414325", "type": "external" } ], "gene_names_uniprotkb": "Nme5; LOC688903", "gene_names_refseq": "Nme5", "protein_names_uniprotkb": "Nucleoside diphosphate kinase 5; Putative 3'-5'-DNA exonuclease NDK5; Radial spoke head protein 23 homolog", "protein_names_refseq": "nucleoside diphosphate kinase homolog 5", "tax_id": 10116, "disease": "hydrocephalus (Disease Ontology:DOID:10908); primary ciliary dyskinesia (Disease Ontology:DOID:9562)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions as part of axonemal radial spoke complexes, which play an important part in the motility of sperm and cilia. In vitro, does not display nucleoside diphosphate kinase (NDPK) activity. Exhibits a 3'-5'-DNA exonuclease activity that removes single nucleotides from the 3' terminus of single-stranded DNA substrates and digests overhanging mismatched 3' termini from double-stranded DNA substrates, possibly participating in DNA nucleolytic processing. Confers protection from cell death mediated by BAX and alters the cellular levels of several antioxidant enzymes, including GPX5. Might be involved in spermiogenesis by enhancing the ability of late-stage spermatids to eliminate reactive oxygen species., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity;GO:0004550 nucleoside diphosphate kinase activity;GO:0008296 3'-5'-DNA exonuclease activity", "go_cellular_component": "GO:0005929 cilium;GO:0001534 radial spoke;GO:0005576 extracellular region;GO:0036126 sperm flagellum;GO:0097729 9+2 motile cilium", "go_biological_process": "GO:0007286 spermatid development;GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0003341 cilium movement;GO:0006183 GTP biosynthetic process;GO:0006228 UTP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZH90-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZHB4-1", "uniprot_id": [ { "id": "D3ZHB4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZHB4", "type": "external" } ], "mass": 27108.0, "length": 246, "protein_name": "Ly6/Plaur domain containing 4", "gene_name": "Lypd4", "organism": "Rat", "refseq_name": "ly6/PLAUR domain-containing protein 4 precursor", "refseq_ac": [ { "id": "NP_001103765", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103765", "type": "external" } ], "gene_names_uniprotkb": "Lypd4", "gene_names_refseq": "Lypd4; rCG53718", "protein_names_uniprotkb": "Ly6/Plaur domain containing 4", "protein_names_refseq": "ly6/PLAUR domain-containing protein 4 precursor; ly6/PLAUR domain-containing protein 4-like; ly6/PLAUR domain-containing protein 4", "tax_id": 10116, "disease": "", "pathway": " (rno:681194); (R-RNO-163125)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0044853 plasma membrane raft;GO:0001669 acrosomal vesicle", "go_biological_process": "GO:0007339 binding of sperm to zona pellucida;GO:0007338 single fertilization;GO:0160131 sperm migration through the uterotubal junction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZHB4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZHE3-1", "uniprot_id": [ { "id": "D3ZHE3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZHE3", "type": "external" } ], "mass": 105266.0, "length": 945, "protein_name": "Zinc finger SWIM-type containing 9", "gene_name": "Zswim9", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zswim9; RGD1310257", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger SWIM-type containing 9", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:308381)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "", "go_biological_process": "GO:0002244 hematopoietic progenitor cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZHE3-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZHY4-1", "uniprot_id": [ { "id": "D3ZHY4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZHY4", "type": "external" } ], "mass": 32959.0, "length": 290, "protein_name": "Glycine N-acyltransferase-like protein", "gene_name": "Glyatl3", "organism": "Rat", "refseq_name": "glycine N-acyltransferase-like protein 3", "refseq_ac": [ { "id": "NP_001138534", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138534", "type": "external" } ], "gene_names_uniprotkb": "Glyatl3", "gene_names_refseq": "Glyatl3", "protein_names_uniprotkb": "Glycine N-acyltransferase-like protein; 2.3.1.-", "protein_names_refseq": "glycine N-acyltransferase-like protein 3", "tax_id": 10116, "disease": "", "pathway": " (rno:688536); (R-RNO-159424); (R-RNO-177128); (R-RNO-177135); (R-RNO-9749641)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the conjugation of long-chain fatty acyl-CoA thioester and glycine to produce long-chain N-(fatty acyl)glycine, an intermediate in the primary fatty acid amide biosynthetic pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" }, { "id": "2.3.1.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.13", "type": "external" }, { "id": "2.3.1.71", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.71", "type": "external" } ], "go_molecular_function": "GO:0047961 glycine N-acyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZHY4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZID6-1", "uniprot_id": [ { "id": "D3ZID6_RAT", "url": "https://www.uniprot.org/uniprot/D3ZID6", "type": "external" } ], "mass": 36345.0, "length": 322, "protein_name": "Olfactory receptor", "gene_name": "Or51a7b", "organism": "Rat", "refseq_name": "olfactory receptor Olr68", "refseq_ac": [ { "id": "NP_001000133", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000133", "type": "external" } ], "gene_names_uniprotkb": "Or51a7b; Or51a7", "gene_names_refseq": "Olr68; Or51a7b; Or51a7; Or51a; ratchr1-160844789-160845757_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 68; olfactory receptor Olr68; olfactory receptor family 51 subfamily A member 7; olfactory receptor gene Olr68", "tax_id": 10116, "disease": "", "pathway": " (rno:293214)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0071396 cellular response to lipid", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZID6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZIF4-1", "uniprot_id": [ { "id": "D3ZIF4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZIF4", "type": "external" } ], "mass": 139501.0, "length": 1315, "protein_name": "Sal-like protein 1", "gene_name": "Sall1", "organism": "Rat", "refseq_name": "sal-like protein 1", "refseq_ac": [ { "id": "NP_001100885", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100885", "type": "external" } ], "gene_names_uniprotkb": "Sall1", "gene_names_refseq": "Sall1", "protein_names_uniprotkb": "Sal-like protein 1", "protein_names_refseq": "sal-like 1; sal-like protein 1", "tax_id": 10116, "disease": "Townes-Brocks syndrome (Disease Ontology:DOID:0050887); middle lobe syndrome (Disease Ontology:DOID:2810); carcinoma (Disease Ontology:DOID:305); renal Wilms' tumor (Disease Ontology:DOID:5176); hepatoblastoma (Disease Ontology:DOID:687); chronic kidney disease (Disease Ontology:DOID:784)", "pathway": " (rno:307740)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcriptional repressor involved in organogenesis. Plays an essential role in ureteric bud invasion during kidney development., [UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0044877 protein-containing complex binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000792 heterochromatin;GO:0010369 chromocenter;GO:0016581 NuRD complex", "go_biological_process": "GO:0061034 olfactory bulb mitral cell layer development;GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0021553 olfactory nerve development;GO:0072092 ureteric bud invasion;GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZIF4-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZIK8-1", "uniprot_id": [ { "id": "D3ZIK8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZIK8", "type": "external" } ], "mass": 133778.0, "length": 1190, "protein_name": "F-box protein 38", "gene_name": "Fbxo38", "organism": "Rat", "refseq_name": "F-box only protein 38", "refseq_ac": [ { "id": "NP_001358950", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001358950", "type": "external" } ], "gene_names_uniprotkb": "Fbxo38", "gene_names_refseq": "Fbxo38", "protein_names_uniprotkb": "F-box protein 38", "protein_names_refseq": "F-box only protein 38", "tax_id": 10116, "disease": "autosomal dominant distal hereditary motor neuronopathy 6 (Disease Ontology:DOID:0111210)", "pathway": " (rno:307390)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0002842 positive regulation of T cell mediated immune response to tumor cell;GO:0010976 positive regulation of neuron projection development;GO:0070936 protein K48-linked ubiquitination;GO:0050870 positive regulation of T cell activation;GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZIK8-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZIM0-1", "uniprot_id": [ { "id": "D3ZIM0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZIM0", "type": "external" } ], "mass": 76502.0, "length": 688, "protein_name": "Interleukin-17 receptor C", "gene_name": "Il17rc", "organism": "Rat", "refseq_name": "interleukin-17 receptor C isoform X1", "refseq_ac": [ { "id": "XP_017448066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017448066", "type": "external" } ], "gene_names_uniprotkb": "Il17rc", "gene_names_refseq": "Il17rc", "protein_names_uniprotkb": "Interleukin-17 receptor C; Interleukin-17 receptor-like protein; ZcytoR14", "protein_names_refseq": "interleukin-17 receptor C isoform X1", "tax_id": 10116, "disease": "chronic mucocutaneous candidiasis (Disease Ontology:DOID:2058); interstitial lung disease (Disease Ontology:DOID:3082)", "pathway": " (rno:297520)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, 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Mediates the electroneutral exchange of endosomal luminal H(+) for a cytosolic Na(+) or K(+). By facilitating proton efflux, SLC9A6 counteracts the acidity generated by vacuolar (V)-ATPase, thereby limiting luminal acidification. Responsible for alkalizing and maintaining the endosomal pH, and consequently in, e.g., endosome maturation and trafficking of recycling endosomal cargo (By similarity). Plays a critical role during neurodevelopment by regulating synaptic development and plasticity (By similarity). Implicated in the maintenance of cell polarity in a manner that is dependent on its ability to modulate intravesicular pH (By similarity). Regulates intracellular pH in some specialized cells, osteoclasts and stereocilia where this transporter localizes to the plasma membrane (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015385 sodium:proton antiporter activity;GO:0015386 potassium:proton antiporter activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005768 endosome;GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0030425 dendrite", "go_biological_process": "GO:0050808 synapse organization;GO:0048812 neuron projection morphogenesis;GO:0060996 dendritic spine development;GO:0030010 establishment of cell polarity;GO:0048675 axon extension", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZJ86-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZJE2-1", "uniprot_id": [ { "id": "D3ZJE2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZJE2", "type": "external" } ], "mass": 22416.0, "length": 203, "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "Rpl12-ps1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rpl12-ps1", "gene_names_refseq": "", "protein_names_uniprotkb": "Large ribosomal subunit protein uL11; 60S ribosomal protein L12", "protein_names_refseq": "", "tax_id": 10116, "disease": "systemic lupus erythematosus (Disease Ontology:DOID:9074)", "pathway": " (R-RNO-156827); (R-RNO-1799339); (R-RNO-6791226); (R-RNO-72689); (R-RNO-72706); (R-RNO-975956); (R-RNO-975957); (R-RNO-9954709); (R-RNO-9954714); (R-RNO-9954716)", "pathway_count": 10, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds directly to 26S ribosomal RNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome;GO:0070180 large ribosomal subunit rRNA binding", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZJE2-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZJK2-1", "uniprot_id": [ { "id": "D3ZJK2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZJK2", "type": "external" } ], "mass": 44217.0, "length": 387, "protein_name": "Serpin family B member 3A", "gene_name": "Serpinb3", "organism": "Rat", "refseq_name": "serpin family B member 3", "refseq_ac": [ { "id": "NP_001382662", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382662", "type": "external" } ], "gene_names_uniprotkb": "Serpinb3; Serpinb3a", "gene_names_refseq": "Serpinb3", "protein_names_uniprotkb": "Serpin family B member 3A", "protein_names_refseq": "serine protease inhibitor B3; serpin family B member 3; serpin peptidase inhibitor, clade B (ovalbumin), member 3", "tax_id": 10116, "disease": "alpha 1-antitrypsin deficiency (Disease Ontology:DOID:13372)", "pathway": " (rno:498209)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0002020 protease binding;GO:0004867 serine-type endopeptidase inhibitor activity;GO:0019899 enzyme binding;GO:0004869 cysteine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0070062 extracellular exosome;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0042270 protection from natural killer cell mediated cytotoxicity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZJK2-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZJK3-1", "uniprot_id": [ { "id": "D3ZJK3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZJK3", "type": "external" } ], "mass": 20785.0, "length": 182, "protein_name": "Histone deacetylase complex subunit SAP30L", "gene_name": "Sap30l", "organism": "Rat", "refseq_name": "histone deacetylase complex subunit SAP30L", "refseq_ac": [ { "id": "NP_001385727", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385727", "type": "external" } ], "gene_names_uniprotkb": "Sap30l", "gene_names_refseq": "RGD1309585; Sap30l", "protein_names_uniprotkb": "Histone deacetylase complex subunit SAP30L; Sin3 corepressor complex subunit SAP30L; Sin3-associated protein p30-like", "protein_names_refseq": "histone deacetylase complex subunit SAP30L", "tax_id": 10116, "disease": "", "pathway": " (rno:360531); (R-RNO-3214815)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Functions as a transcription repressor, probably via its interaction with histone deacetylase complexes. Involved in the functional recruitment of the class 1 Sin3-histone deacetylase complex (HDAC) to the nucleolus. Binds DNA, apparently without sequence-specificity, and bends bound double-stranded DNA. Binds phosphoinositol phosphates (phosphoinositol 3-phosphate, phosphoinositol 4-phosphate and phosphoinositol 5-phosphate) via the same basic sequence motif that mediates DNA binding and nuclear import., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0010314 phosphatidylinositol-5-phosphate binding;GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0042393 histone binding;GO:0070273 phosphatidylinositol-4-phosphate binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0001650 fibrillar center;GO:0000118 histone deacetylase complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZJK3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZJT4-1", "uniprot_id": [ { "id": "D3ZJT4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZJT4", "type": "external" } ], "mass": 34108.0, "length": 315, "protein_name": "60S acidic ribosomal protein P0", "gene_name": "Rplp0l1", "organism": "Rat", "refseq_name": "large ribosomal subunit protein uL10-like", "refseq_ac": [ { "id": "XP_227546", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_227546", "type": "external" } ], "gene_names_uniprotkb": "Rplp0l1", "gene_names_refseq": "Rplp0l1", "protein_names_uniprotkb": "60S acidic ribosomal protein P0", "protein_names_refseq": "large ribosomal subunit protein uL10-like", "tax_id": 10116, "disease": "", "pathway": " (rno:295340)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Ribosomal protein P0 is the functional equivalent of E.coli protein L10., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome;GO:0070180 large ribosomal subunit rRNA binding", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0042254 ribosome biogenesis;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZJT4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZJU8-1", "uniprot_id": [ { "id": "D3ZJU8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZJU8", "type": "external" } ], "mass": 33485.0, "length": 297, "protein_name": "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "gene_name": "ENSRNOG00000069573", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ENSRNOG00000069573", "gene_names_refseq": "", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase PP1-beta catalytic subunit; 3.1.3.53", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.53", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" } ], "go_molecular_function": "GO:0050115 myosin-light-chain-phosphatase activity;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0042752 regulation of circadian rhythm;GO:0032922 circadian regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZJU8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZK57-1", "uniprot_id": [ { "id": "D3ZK57_RAT", "url": "https://www.uniprot.org/uniprot/D3ZK57", "type": "external" } ], "mass": 11783.0, "length": 105, "protein_name": "Immunoglobulin heavy chain like 7", "gene_name": "Ighl7", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ighl7", "gene_names_refseq": "", "protein_names_uniprotkb": "Immunoglobulin heavy chain like 7", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003823 antigen binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0016064 immunoglobulin mediated immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZK57-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZK71-1", "uniprot_id": [ { "id": "D3ZK71_RAT", "url": "https://www.uniprot.org/uniprot/D3ZK71", "type": "external" } ], "mass": 25850.0, "length": 224, "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07036505.1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AABR07036505.1", "gene_names_refseq": "", "protein_names_uniprotkb": "N-terminal Ras-GEF domain-containing protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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activity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQ80-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQ86-1", "uniprot_id": [ { "id": "D3ZQ86_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQ86", "type": "external" } ], "mass": 86990.0, "length": 812, "protein_name": "Immunoglobulin superfamily DCC subclass member 3", "gene_name": "Igdcc3", "organism": "Rat", "refseq_name": "immunoglobulin superfamily DCC subclass member 3 isoform 1 precursor", "refseq_ac": [ { "id": "NP_001359088", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001359088", "type": "external" } ], "gene_names_uniprotkb": "Igdcc3", "gene_names_refseq": "Igdcc3; Punc", "protein_names_uniprotkb": "Immunoglobulin superfamily DCC subclass member 3; Putative neuronal cell adhesion molecule", "protein_names_refseq": "immunoglobulin superfamily DCC subclass member 3 isoform 1 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"Rpa3l1", "organism": "Rat", "refseq_name": "replication protein A 14 kDa subunit-like", "refseq_ac": [ { "id": "XP_038946131", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038946131", "type": "external" } ], "gene_names_uniprotkb": "Rpa3l1; AC095390.1; LOC100362927", "gene_names_refseq": "Rpa3l1", "protein_names_uniprotkb": "Replication protein A 14 kDa subunit; Replication factor A protein 3", "protein_names_refseq": "replication protein A 14 kDa subunit-like", "tax_id": 10116, "disease": "", "pathway": " (rno:100362927)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003684 damaged DNA binding;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0035861 site of double-strand break;GO:0005662 DNA replication factor A complex", "go_biological_process": "GO:0006284 base-excision repair;GO:0006260 DNA replication;GO:0006298 mismatch repair;GO:0000724 double-strand break repair via homologous recombination;GO:0006289 nucleotide-excision repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQ91-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQ96-1", "uniprot_id": [ { "id": "D3ZQ96_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQ96", "type": "external" } ], "mass": 17868.0, "length": 155, "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "organism": "Rat", "refseq_name": "large ribosomal subunit protein eL21-like", "refseq_ac": [ { "id": "XP_038954123", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038954123", "type": "external" } ], "gene_names_uniprotkb": "LOC102550668; AABR07043626.1", "gene_names_refseq": "LOC102550668", "protein_names_uniprotkb": "Large ribosomal subunit protein eL21; 60S ribosomal protein L21", "protein_names_refseq": "large ribosomal subunit protein eL21-like", "tax_id": 10116, "disease": "", "pathway": " (rno:102550668)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQ96-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQH5-1", "uniprot_id": [ { "id": "D3ZQH5_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQH5", "type": "external" } ], "mass": 78403.0, "length": 700, "protein_name": "Myotubularin related protein 11", "gene_name": "Mtmr11", "organism": "Rat", "refseq_name": "myotubularin-related protein 11", "refseq_ac": [ { "id": "NP_001178025", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178025", "type": "external" } ], "gene_names_uniprotkb": "Mtmr11", "gene_names_refseq": "Mtmr11", "protein_names_uniprotkb": "Myotubularin related protein 11", "protein_names_refseq": "myotubularin-related protein 11", "tax_id": 10116, "disease": "neurodegenerative disease (Disease Ontology:DOID:1289)", "pathway": " (rno:689613)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQH5-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQQ8-1", "uniprot_id": [ { "id": "D3ZQQ8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQQ8", "type": "external" } ], "mass": 18386.0, "length": 163, "protein_name": "Leucine rich colipase-like 1", "gene_name": "Lrcol1", "organism": "Rat", "refseq_name": "leucine-rich colipase-like protein 1 precursor", "refseq_ac": [ { "id": "NP_001257347", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257347", "type": "external" } ], "gene_names_uniprotkb": "Lrcol1", "gene_names_refseq": "Clpsl3; Lrcol1", "protein_names_uniprotkb": "Leucine rich colipase-like 1", "protein_names_refseq": "leucine-rich colipase-like protein 1 precursor; leucine-rich colipase-like protein 1; rCG21611-like", "tax_id": 10116, "disease": "", "pathway": " (rno:100363238)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008047 enzyme activator activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0016042 lipid catabolic process;GO:0007586 digestion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQQ8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQW7-1", "uniprot_id": [ { "id": "D3ZQW7_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQW7", "type": "external" } ], "mass": 28626.0, "length": 267, "protein_name": "Small ribosomal subunit protein uS5", "gene_name": "AC136661.1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AC136661.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Small ribosomal subunit protein uS5; 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The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays a role in the assembly and function of the 40S ribosomal subunit. Mutations in this protein affects the control of translational fidelity. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022627 cytosolic small ribosomal subunit;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQW7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZR49-1", "uniprot_id": [ { "id": "D3ZR49_RAT", "url": "https://www.uniprot.org/uniprot/D3ZR49", "type": "external" } ], "mass": 72828.0, "length": 641, "protein_name": "alpha-1,2-Mannosidase", "gene_name": "Man1a2", "organism": "Rat", "refseq_name": "mannosyl-oligosaccharide 1,2-alpha-mannosidase IB", "refseq_ac": [ { "id": "NP_001099922", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099922", "type": "external" } ], "gene_names_uniprotkb": "Man1a2", "gene_names_refseq": "Man1a2; Man1b", "protein_names_uniprotkb": "alpha-1,2-Mannosidase; 3.2.1.-", "protein_names_refseq": "mannosidase 1, beta; mannosyl-oligosaccharide 1,2-alpha-mannosidase IB", "tax_id": 10116, "disease": "", "pathway": " (rno:295319); (R-RNO-964827)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.-", "type": "external" }, { "id": "3.2.1.113", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.113", "type": "external" } ], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016020 membrane", "go_biological_process": "GO:0048286 lung alveolus development;GO:0005975 carbohydrate metabolic process;GO:0007585 respiratory gaseous exchange by respiratory system;GO:0036503 ERAD pathway;GO:0009100 glycoprotein metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZR49-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZR58-1", "uniprot_id": [ { "id": "D3ZR58_RAT", "url": "https://www.uniprot.org/uniprot/D3ZR58", "type": "external" } ], "mass": 18551.0, "length": 157, "protein_name": "IQ motif containing F6", "gene_name": "Iqcf6", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Iqcf6", "gene_names_refseq": "", "protein_names_uniprotkb": "IQ motif containing F6", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:503229)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZR58-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZRD5-1", "uniprot_id": [ { "id": "D3ZRD5_RAT", "url": "https://www.uniprot.org/uniprot/D3ZRD5", "type": "external" } ], "mass": 30571.0, "length": 262, "protein_name": "IZUMO family member 3", "gene_name": "Izumo3", "organism": "Rat", "refseq_name": "izumo sperm-egg fusion protein 3 isoform X1", "refseq_ac": [ { "id": "XP_002729548", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002729548", "type": "external" } ], "gene_names_uniprotkb": "Izumo3", "gene_names_refseq": "Izumo3", "protein_names_uniprotkb": "IZUMO family member 3", "protein_names_refseq": "izumo sperm-egg fusion protein 3 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:100362588); (R-RNO-1300645)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0002079 inner acrosomal membrane", "go_biological_process": "GO:0001675 acrosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZRD5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZRK8-1", "uniprot_id": [ { "id": "D3ZRK8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZRK8", "type": "external" } ], "mass": 102571.0, "length": 901, "protein_name": "Patched domain containing 4", "gene_name": "Ptchd4", "organism": "Rat", "refseq_name": "patched domain-containing protein 4 isoform X2", "refseq_ac": [ { "id": "XP_008765136", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008765136", "type": "external" } ], "gene_names_uniprotkb": "Ptchd4", "gene_names_refseq": "Ptchd4", "protein_names_uniprotkb": "Patched domain containing 4", "protein_names_refseq": "patched domain-containing protein 4 isoform X2", "tax_id": 10116, "disease": "", "pathway": " (rno:301271)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZRK8-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZS67-1", "uniprot_id": [ { "id": "D3ZS67_RAT", "url": "https://www.uniprot.org/uniprot/D3ZS67", "type": "external" } ], "mass": 138354.0, "length": 1270, "protein_name": "Photoreceptor cilium actin regulator", "gene_name": "Pcare", "organism": "Rat", "refseq_name": "photoreceptor cilium actin regulator", "refseq_ac": [ { "id": "NP_001386165", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386165", "type": "external" } ], "gene_names_uniprotkb": "Pcare; RGD1304963", "gene_names_refseq": "Pcare; RGD1304963", "protein_names_uniprotkb": "Photoreceptor cilium actin regulator", "protein_names_refseq": "photoreceptor cilium actin regulator; uncharacterized protein C2orf71 homolog", "tax_id": 10116, "disease": "retinitis pigmentosa 54 (Disease Ontology:DOID:0110364)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005929 cilium;GO:0001917 photoreceptor inner segment;GO:0001750 photoreceptor outer segment", "go_biological_process": "GO:0035845 photoreceptor cell outer segment organization;GO:1903546 protein localization to photoreceptor outer segment", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZS67-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZSG7-1", "uniprot_id": [ { "id": "D3ZSG7_RAT", "url": "https://www.uniprot.org/uniprot/D3ZSG7", "type": "external" } ], "mass": 27082.0, "length": 237, "protein_name": "Spermatogenesis associated multipass transmembrane protein 1", "gene_name": "Samt1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Samt1; LOC685789", "gene_names_refseq": "", "protein_names_uniprotkb": "Spermatogenesis associated multipass transmembrane protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:685789)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005923 bicellular tight junction", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZSG7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZSI9-1", "uniprot_id": [ { "id": "D3ZSI9_RAT", "url": "https://www.uniprot.org/uniprot/D3ZSI9", "type": "external" } ], "mass": 36143.0, "length": 321, "protein_name": "Olfactory receptor", "gene_name": "Or5bb12", "organism": "Rat", "refseq_name": "olfactory receptor Olr327", "refseq_ac": [ { "id": "NP_001000249", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000249", "type": "external" } ], "gene_names_uniprotkb": "Or5bb12", "gene_names_refseq": "Olr327; Or5bb12; ratchr1-215197449-215196484_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 327; olfactory receptor Olr327; olfactory receptor gene Olr327", "tax_id": 10116, "disease": "", "pathway": " (rno:293765)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZSI9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZSM9-1", "uniprot_id": [ { "id": "D3ZSM9_RAT", "url": "https://www.uniprot.org/uniprot/D3ZSM9", "type": "external" } ], "mass": 88476.0, "length": 816, "protein_name": "Integrator complex assembly factor BRAT1", "gene_name": "Brat1", "organism": "Rat", "refseq_name": "BRCA1-associated ATM activator 1 isoform 1", "refseq_ac": [ { "id": "NP_001418778", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418778", "type": "external" } ], "gene_names_uniprotkb": "Brat1", "gene_names_refseq": "Brat1-ps1; Brat1; RGD1565146", "protein_names_uniprotkb": "Integrator complex assembly factor BRAT1; BRCA1-associated ATM activator 1; BRCA1-associated protein required for ATM activation protein 1", "protein_names_refseq": "BRCA1-associated ATM activator 1 isoform 1; BRCA1-associated ATM activator 1, pseudogene 1", "tax_id": 10116, "disease": "", "pathway": " (rno:498150)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of a multiprotein complex required for the assembly of the RNA endonuclease module of the integrator complex. Associates with INTS9 and INTS11 in the cytoplasm and blocks the active site of INTS11 to inhibit the endonuclease activity of INTS11 before formation of the full integrator complex. Following dissociation of WDR73 of the complex, BRAT1 facilitates the nuclear import of the INTS9-INTS11 heterodimer. In the nucleus, INTS4 is integrated to the INTS9-INTS11 heterodimer and BRAT1 is released from the mature RNA endonuclease module by inositol hexakisphosphate (InsP6). BRAT1 is also involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress. Plays a role in regulating mitochondrial function and cell proliferation. Required for protein stability of MTOR and MTOR-related proteins, and cell cycle progress by growth factors., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0008428 ribonuclease inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0001934 positive regulation of protein phosphorylation;GO:0008283 cell population proliferation;GO:0016477 cell migration;GO:0030307 positive regulation of cell growth;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZSM9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZSR2-1", "uniprot_id": [ { "id": "D3ZSR2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZSR2", "type": "external" } ], "mass": 63359.0, "length": 572, "protein_name": "Polyadenylate-binding protein", "gene_name": "Pabpc4-ps1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Pabpc4-ps1; RGD1562451", "gene_names_refseq": "", "protein_names_uniprotkb": "Polyadenylate-binding protein; PABP", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binds the poly(A) tail of mRNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003730 mRNA 3'-UTR binding;GO:0008143 poly(A) binding;GO:0008266 poly(U) RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0010494 cytoplasmic stress granule;GO:1990904 ribonucleoprotein complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZSR2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZSW3-1", "uniprot_id": [ { "id": "D3ZSW3_RAT", "url": "https://www.uniprot.org/uniprot/D3ZSW3", "type": "external" } ], "mass": 58102.0, "length": 509, "protein_name": "IKAROS family zinc finger 3", "gene_name": "Ikzf3", "organism": "Rat", "refseq_name": "zinc finger protein Aiolos", "refseq_ac": [ { "id": "NP_001100517", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100517", "type": "external" } ], "gene_names_uniprotkb": "Ikzf3", "gene_names_refseq": "Ikzf3; Zfpn1a3", "protein_names_uniprotkb": "IKAROS family zinc finger 3", "protein_names_refseq": "zinc finger protein Aiolos; zinc finger protein, subfamily 1A, 3 (Aiolos)", "tax_id": 10116, "disease": "small cell carcinoma (Disease Ontology:DOID:0050685); immunodeficiency 84 (Disease Ontology:DOID:0061054); childhood-onset asthma (Disease Ontology:DOID:0080815); atherosclerosis (Disease Ontology:DOID:1936); lung non-small cell carcinoma (Disease Ontology:DOID:3908); systemic lupus erythematosus (Disease Ontology:DOID:9074)", "pathway": " (rno:303511); (R-RNO-9940951)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0045577 regulation of B cell differentiation;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0009617 response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZSW3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZSW4-1", "uniprot_id": [ { "id": "D3ZSW4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZSW4", "type": "external" } ], "mass": 58200.0, "length": 525, "protein_name": "Cornulin", "gene_name": "Crnn", "organism": "Rat", "refseq_name": "cornulin", "refseq_ac": [ { "id": "NP_001414358", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414358", "type": "external" } ], "gene_names_uniprotkb": "Crnn", "gene_names_refseq": "Crnn; 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Translation reinitiation is the process where the small ribosomal subunit remains attached to the mRNA following termination of translation of a regulatory upstream ORF (uORF), and resume scanning on the same mRNA molecule to initiate translation of a downstream ORF, usually the main ORF (mORF). The MCTS1/DENR complex is pivotal to two linked mechanisms essential for translation reinitiation. Firstly, the dissociation of deacylated tRNAs from post-termination 40S ribosomal complexes during ribosome recycling. Secondly, the recruitment in an EIF2-independent manner of aminoacylated initiator tRNA to P site of 40S ribosomes for a new round of translation. 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Epithelial cell-transforming sequence 2 oncogene", "protein_names_refseq": "ect2 oncogene; epithelial cell transforming sequence 2 oncogene; protein ECT2", "tax_id": 10116, "disease": "", "pathway": " (rno:361921); (R-RNO-193648); (R-RNO-416482); (R-RNO-8980692); (R-RNO-9013026); (R-RNO-9013148); (R-RNO-9013149)", "pathway_count": 7, "publication_count": 2, "publication_id_list": "22673903;25807302", "class_list": "", "function": "We thus conclude that Ect2 is involved in annexin V-induced rat Leydig cell proliferation through the RhoA/ROCK pathway Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0042803 protein homodimerization activity;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005911 cell-cell junction", "go_biological_process": "GO:0042307 positive regulation of protein import into nucleus;GO:1903438 positive regulation of mitotic cytokinetic process;GO:0007399 nervous system development;GO:0015031 protein transport;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZUD0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZUE8-1", "uniprot_id": [ { "id": "D3ZUE8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZUE8", "type": "external" } ], "mass": 196493.0, "length": 1809, "protein_name": "Stereocilin", "gene_name": "Strc", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Strc", "gene_names_refseq": "", "protein_names_uniprotkb": "Stereocilin", "protein_names_refseq": "", "tax_id": 10116, "disease": "autosomal recessive nonsyndromic deafness 16 (Disease Ontology:DOID:0110471); sensorineural hearing loss (Disease Ontology:DOID:10003)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0009986 cell surface;GO:0060091 kinocilium;GO:0032426 stereocilium tip", "go_biological_process": "GO:0050910 detection of mechanical stimulus involved in sensory perception of sound;GO:0007160 cell-matrix adhesion;GO:0008104 intracellular protein localization;GO:0060088 auditory receptor cell stereocilium organization;GO:0060122 inner ear receptor cell stereocilium organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZUE8-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZUF0-1", "uniprot_id": [ { "id": "D3ZUF0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZUF0", "type": "external" } ], "mass": 337237.0, "length": 3072, "protein_name": "Myosin XVB", "gene_name": "Myo15b", "organism": "Rat", "refseq_name": "myosin XVB", "refseq_ac": [ { "id": "NP_001389323", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001389323", "type": "external" } ], "gene_names_uniprotkb": "Myo15b", "gene_names_refseq": "Myo15b; RGD1560214", "protein_names_uniprotkb": "Myosin XVB", "protein_names_refseq": "myosin XVB", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005524 ATP binding;GO:0003774 cytoskeletal motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005903 brush border;GO:0016459 myosin complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZUF0-1", "record_type": "protein", "filter_code": "0000000.0000000.001000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZUG5-1", "uniprot_id": [ { "id": "D3ZUG5_RAT", "url": "https://www.uniprot.org/uniprot/D3ZUG5", "type": "external" } ], "mass": 7927.0, "length": 76, "protein_name": "Energy homeostasis associated", "gene_name": "Enho", "organism": "Rat", "refseq_name": "adropin", "refseq_ac": [ { "id": "NP_001269265", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269265", "type": "external" } ], "gene_names_uniprotkb": "Enho; LOC100912292", "gene_names_refseq": "Enho; RGD1565232", "protein_names_uniprotkb": "Energy homeostasis associated", "protein_names_refseq": "adropin-like; adropin", "tax_id": 10116, "disease": "", "pathway": " (rno:100912292)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "23620340;24932661;32798458;33781005;36216130;37933453;39337311", "class_list": "", "function": "Adropin Is Expressed in Pancreatic Islet Cells and Reduces Glucagon Release in Diabetes Mellitus. Publication Status: Online-Only, [RefSeq, PubMed]; Adropin increases with swimming exercise and exerts a protective effect on the brain of aged rats., [RefSeq, PubMed]; Adropin stimulates proliferation but suppresses differentiation in rat primary brown preadipocytes., [RefSeq, PubMed]; Data show that adropin (ADR) is expressed in various tissues in the rats and its levels increased in STZ-induced diabetes., [RefSeq, PubMed]; Effects of irisin and exercise on adropin and betatrophin in a new metabolic syndrome model., [RefSeq, PubMed]; The effect of thyroid dysfunction and treatment on adropin, asprosin and preptin levels in rats. Publication Status: Online-Only, [RefSeq, PubMed]; The findings elucidate the pathogenesis of MI, and the gradual increase in serum adropin could be a novel diagnostic marker and serve as an alternative to troponin-I measurement for diagnosing MI., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005179 hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0097009 energy homeostasis;GO:0045747 positive regulation of Notch signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "D3ZUG5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZV40-1", "uniprot_id": [ { "id": "D3ZV40_RAT", "url": "https://www.uniprot.org/uniprot/D3ZV40", "type": "external" } ], "mass": 97596.0, "length": 898, "protein_name": "Unk zinc finger", "gene_name": "Unk", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Unk", "gene_names_refseq": "", "protein_names_uniprotkb": "Unk zinc finger", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:360663)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043022 ribosome binding;GO:1990715 mRNA CDS binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0001701 in utero embryonic development;GO:0001764 neuron migration;GO:0048667 cell morphogenesis involved in neuron differentiation;GO:2000766 negative regulation of cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZV40-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZV46-1", "uniprot_id": [ { "id": "D3ZV46_RAT", "url": "https://www.uniprot.org/uniprot/D3ZV46", "type": "external" } ], "mass": 71717.0, "length": 622, "protein_name": "Pogo transposable element derived with KRAB domain", "gene_name": "Pogk", "organism": "Rat", "refseq_name": "pogo transposable element with KRAB domain", "refseq_ac": [ { "id": "NP_001100664", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100664", "type": "external" } ], "gene_names_uniprotkb": "Pogk", "gene_names_refseq": "Pogk", "protein_names_uniprotkb": "Pogo transposable element derived with KRAB domain", "protein_names_refseq": "pogo transposable element with KRAB domain", "tax_id": 10116, "disease": "", "pathway": " (rno:304941)", "pathway_count": 1, "publication_count": 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0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZV46-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZV50-1", "uniprot_id": [ { "id": "D3ZV50_RAT", "url": "https://www.uniprot.org/uniprot/D3ZV50", "type": "external" } ], "mass": 22788.0, "length": 195, "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rps9l1; RGD1566136", "gene_names_refseq": "", "protein_names_uniprotkb": "Small ribosomal subunit protein uS4; 40S ribosomal protein S9", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:300278)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019843 rRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005730 nucleolus;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZV50-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZV60-1", "uniprot_id": [ { "id": "D3ZV60_RAT", "url": "https://www.uniprot.org/uniprot/D3ZV60", "type": "external" } ], "mass": 281969.0, "length": 2439, "protein_name": "Centromere-associated protein E", "gene_name": "Cenpe", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cenpe", "gene_names_refseq": "", "protein_names_uniprotkb": "Centromere-associated protein E; 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uncharacterized protein LOC685067", "tax_id": 10116, "disease": "", "pathway": " (rno:685067)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0031410 cytoplasmic vesicle;GO:0020005 symbiont-containing vacuole membrane", "go_biological_process": "GO:0044406 adhesion of symbiont to host;GO:0050830 defense response to Gram-positive bacterium;GO:0051607 defense response to virus;GO:0042742 defense response to bacterium;GO:0071346 cellular response to type II interferon", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZV82-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZVA9-1", "uniprot_id": [ { "id": "D3ZVA9_RAT", "url": "https://www.uniprot.org/uniprot/D3ZVA9", "type": "external" } ], "mass": 37815.0, "length": 328, "protein_name": "Acyltransferase", "gene_name": "Awat1", "organism": "Rat", "refseq_name": "acyl-CoA wax alcohol acyltransferase 1", "refseq_ac": [ { "id": "NP_001102841", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102841", "type": "external" } ], "gene_names_uniprotkb": "Awat1", "gene_names_refseq": "Awat1; Dgat2l3", "protein_names_uniprotkb": "Acyltransferase; 2.3.1.-", "protein_names_refseq": "acyl-CoA wax alcohol acyltransferase 1; diacylglycerol O-acyltransferase 2-like 3; wax synthase 1", "tax_id": 10116, "disease": "", "pathway": " (rno:679520); (R-RNO-2142753); (R-RNO-9640463)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" } ], "go_molecular_function": "GO:0047196 long-chain-alcohol O-fatty-acyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZVA9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZXM6-1", "uniprot_id": [ { "id": "D3ZXM6_RAT", "url": "https://www.uniprot.org/uniprot/D3ZXM6", "type": "external" } ], "mass": 24520.0, "length": 209, "protein_name": "C-type lectin domain family 6, member A, pseudogene 1", "gene_name": "Clec6a-ps1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Clec6a-ps1", "gene_names_refseq": "", "protein_names_uniprotkb": "C-type lectin domain family 6, member A, pseudogene 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-5621480); (R-RNO-6798695)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0005509 calcium ion binding;GO:0005537 D-mannose binding;GO:0038187 pattern recognition receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0045087 innate immune response;GO:0002250 adaptive immune response;GO:0001819 positive regulation of cytokine production;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0002223 stimulatory C-type lectin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZXM6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZVF5-1", "uniprot_id": [ { "id": "D3ZVF5_RAT", "url": "https://www.uniprot.org/uniprot/D3ZVF5", "type": "external" } ], "mass": 14389.0, "length": 125, "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "Rpl31l9", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rpl31l9", "gene_names_refseq": "", "protein_names_uniprotkb": "Large ribosomal subunit protein eL31; 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The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZVF5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZVI2-1", "uniprot_id": [ { "id": "D3ZVI2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZVI2", "type": "external" } ], "mass": 263207.0, "length": 2384, "protein_name": "Transcription activation suppressor family member 2", "gene_name": "Tasor2", "organism": "Rat", "refseq_name": "protein TASOR 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"reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0000785 chromatin;GO:0140286 HUSH2 complex", "go_biological_process": "GO:0045814 negative regulation of gene expression, 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Involved in mediating assembly of both ODAs and their axonemal docking complex onto ciliary microtubules., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, 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Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF), lysophosphatidylcholine (lyso-PC) and N-acylethanolamine lysophospholipids. Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, 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"GO:0005783 endoplasmic reticulum;GO:0048471 perinuclear region of cytoplasm;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0034638 phosphatidylcholine catabolic process;GO:0070291 N-acylethanolamine metabolic process;GO:0046475 glycerophospholipid catabolic process;GO:0006644 phospholipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A1N8-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A1P8-1", "uniprot_id": [ { "id": "D4A1P8_RAT", "url": "https://www.uniprot.org/uniprot/D4A1P8", "type": "external" } ], "mass": 106393.0, "length": 918, "protein_name": "NLR family, pyrin domain containing 4B", "gene_name": "Nlrp4b", "organism": "Rat", "refseq_name": "NACHT, LRR and PYD domains-containing protein 4B", "refseq_ac": [ { "id": "XP_063136648", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063136648", 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true }, { "uniprot_canonical_ac": "D4A206-1", "uniprot_id": [ { "id": "D4A206_RAT", "url": "https://www.uniprot.org/uniprot/D4A206", "type": "external" } ], "mass": 140068.0, "length": 1357, "protein_name": "Treacle ribosome biogenesis factor 1", "gene_name": "Tcof1", "organism": "Rat", "refseq_name": "treacle protein", "refseq_ac": [ { "id": "NP_001382056", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382056", "type": "external" } ], "gene_names_uniprotkb": "Tcof1", "gene_names_refseq": "Tcof1", "protein_names_uniprotkb": "Treacle ribosome biogenesis factor 1", "protein_names_refseq": "Treacher Collins-Franceschetti syndrome 1 homolog; treacle protein", "tax_id": 10116, "disease": "Treacher Collins syndrome 1 (Disease Ontology:DOID:0080789); Treacher Collins syndrome (Disease Ontology:DOID:2908)", "pathway": "", "pathway_count": 0, "publication_count": 4, "publication_id_list": "16641100;22673903;26103128;31141469", "class_list": "", "function": "Acinar Progenitor Cell Model Identifies Treacle-Dependent Radioresistance, [RefSeq, PubMed]; The current work has provided the premier evidence that haloacid dehalogenase-like hydrolase domain containing 2/C18QTL4 and Tcof1/C18QTL3 may be involved in polygenic hypertension., [RefSeq, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, 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"0000000.0000110.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A221-1", "uniprot_id": [ { "id": "D4A221_RAT", "url": "https://www.uniprot.org/uniprot/D4A221", "type": "external" } ], "mass": 54038.0, "length": 471, "protein_name": "Tripartite motif family-like 1", "gene_name": "Triml1", "organism": "Rat", "refseq_name": "tripartite motif family-like 1 isoform 2", "refseq_ac": [ { "id": "NP_001419727", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001419727", "type": "external" } ], "gene_names_uniprotkb": "Triml1", "gene_names_refseq": "RGD1305337; Triml1", "protein_names_uniprotkb": "Tripartite motif family-like 1", "protein_names_refseq": "probable E3 ubiquitin-protein ligase TRIML1; tripartite motif family-like 1 isoform 2", "tax_id": 10116, "disease": "", "pathway": " (rno:290767)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A221-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A290-1", "uniprot_id": [ { "id": "D4A290_RAT", "url": "https://www.uniprot.org/uniprot/D4A290", "type": "external" } ], "mass": 15949.0, "length": 151, "protein_name": "Small ribosomal subunit protein uS11", "gene_name": "LOC120101650", "organism": "Rat", "refseq_name": "small ribosomal subunit protein uS11-like", "refseq_ac": [ { "id": "XP_038962486", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038962486", "type": "external" } ], "gene_names_uniprotkb": "LOC120101650", "gene_names_refseq": "LOC120101650", "protein_names_uniprotkb": "Small ribosomal subunit protein uS11; 40S ribosomal protein S14", "protein_names_refseq": "small ribosomal subunit protein uS11-like", "tax_id": 10116, "disease": "myelodysplastic syndrome (Disease Ontology:DOID:0050908); chromosome 5q deletion syndrome (Disease Ontology:DOID:0090016); anemia (Disease Ontology:DOID:2355)", "pathway": " (rno:120101650)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0000028 ribosomal small subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A290-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A2B1-1", "uniprot_id": [ { "id": "D4A2B1_RAT", "url": "https://www.uniprot.org/uniprot/D4A2B1", "type": "external" } ], "mass": 36858.0, "length": 358, "protein_name": "G-protein coupled receptor 62", "gene_name": "Gpr62", "organism": "Rat", "refseq_name": "G-protein coupled receptor 62", "refseq_ac": [ { "id": "NP_001385842", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385842", "type": "external" } ], "gene_names_uniprotkb": "Gpr62", "gene_names_refseq": "Gpr62; RGD1560166", "protein_names_uniprotkb": "G-protein coupled receptor 62", "protein_names_refseq": "G-protein coupled receptor 62; probable G-protein coupled receptor 62", "tax_id": 10116, "disease": "", "pathway": " (rno:501049)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0042802 identical protein binding;GO:1990763 arrestin family protein binding", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0043235 receptor complex;GO:0010008 endosome membrane", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0050850 positive regulation of calcium-mediated signaling;GO:0038035 ligand-independent adenylate cyclase-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A2B1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A2E6-1", "uniprot_id": [ { "id": "D4A2E6_RAT", "url": "https://www.uniprot.org/uniprot/D4A2E6", "type": "external" } ], "mass": 37562.0, "length": 344, "protein_name": "Low density lipoprotein receptor class A domain containing 2", "gene_name": "Ldlrad2", "organism": "Rat", "refseq_name": "low density lipoprotein receptor class A domain containing 2 precursor", "refseq_ac": [ { "id": "NP_001418162", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418162", "type": "external" } ], "gene_names_uniprotkb": "Ldlrad2", "gene_names_refseq": "Ldlrad2; RGD1564888", "protein_names_uniprotkb": "Low density lipoprotein receptor class A domain containing 2", "protein_names_refseq": "low density lipoprotein receptor A domain containing 2; low density lipoprotein receptor class A domain containing 2 precursor; low-density lipoprotein receptor class A domain-containing protein 2", "tax_id": 10116, "disease": "", "pathway": " (rno:502992)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A2E6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A2G6-1", "uniprot_id": [ { "id": "D4A2G6_RAT", "url": "https://www.uniprot.org/uniprot/D4A2G6", "type": "external" } ], "mass": 129728.0, "length": 1172, "protein_name": "Thrombospondin-2", "gene_name": "Thbs2", "organism": "Rat", "refseq_name": "thrombospondin-2 precursor", "refseq_ac": [ { "id": "NP_001162609", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162609", "type": "external" } ], "gene_names_uniprotkb": "Thbs2", "gene_names_refseq": "TSP-2; Thbs2", "protein_names_uniprotkb": "Thrombospondin-2", "protein_names_refseq": "thrombospondin-2 precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:292406); (R-RNO-186797); (R-RNO-5173214)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "12511771;23541831;28953973;37219820", "class_list": "", "function": "Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties., [UniProtKB, UniProtKB]; In the adult rat retina, TSP2, but not TSP1, secreted by glial cells may be involved in the synaptic plastic process after retinal injury through binding to its neuronal receptor alpha2delta1., [RefSeq, PubMed]; Robust expression of TSP-1 and TSP-2, two major angiostatic factors, was noted in the ischemic brain with different temporal expression profiles from different cellular origins., [RefSeq, PubMed]; The expression levels of glial fibrillary acidic protein (the marker of activated macroglia cells), thrombospondin 2, alpha2delta-1 and presynaptic proteins were increased following elevated hydrostatic pressure in mixed cultures, but the expression levels of postsynaptic proteins were not changed. Publication Status: Online-Only, [RefSeq, PubMed]; Thrombospondin-2 Couples Pressure-Promoted Chondrogenesis through NF-kappaB Signaling., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix;GO:0005604 basement membrane;GO:0031091 platelet alpha granule", "go_biological_process": "GO:0007155 cell adhesion;GO:0051965 positive regulation of synapse assembly;GO:0016525 negative regulation of angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "D4A2G6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A2K5-1", "uniprot_id": [ { "id": "D4A2K5_RAT", "url": "https://www.uniprot.org/uniprot/D4A2K5", "type": "external" } ], "mass": 34758.0, "length": 317, "protein_name": "Nuclear receptor interacting protein 3", "gene_name": "Nrip3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Nrip3", "gene_names_refseq": "", "protein_names_uniprotkb": "Nuclear receptor interacting protein 3", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004190 aspartic-type endopeptidase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A2K5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A2N2-1", "uniprot_id": [ { "id": "D4A2N2_RAT", "url": "https://www.uniprot.org/uniprot/D4A2N2", "type": "external" } ], "mass": 113203.0, "length": 996, "protein_name": "Type II inositol 1,4,5-trisphosphate 5-phosphatase", "gene_name": "Inpp5b", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Inpp5b", "gene_names_refseq": "", "protein_names_uniprotkb": "Type II inositol 1,4,5-trisphosphate 5-phosphatase; 3.1.3.36; 3.1.3.56; Phosphoinositide 5-phosphatase", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:362590); (R-RNO-1855183); (R-RNO-1855204)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulates phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) cellular levels by cleaving the phosphate at the 5-position producing PtdIns(4)P. Also hydrolyzes the 5-position phosphate from inositol 1,4,5-trisphosphate (Ins(1,4,5)P3), thereby modulating cellular signaling events., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.86", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.86", "type": "external" }, { "id": "3.1.3.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.56", "type": "external" }, { "id": "3.1.3.36", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.36", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.3.95", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.95", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016020 membrane;GO:0030670 phagocytic vesicle membrane;GO:0031901 early endosome membrane", "go_biological_process": "GO:0001701 in utero embryonic development;GO:0007165 signal transduction;GO:0046856 phosphatidylinositol dephosphorylation;GO:0007283 spermatogenesis;GO:0030317 flagellated sperm motility", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A2N2-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A3G7-1", "uniprot_id": [ { "id": "D4A3G7_RAT", "url": "https://www.uniprot.org/uniprot/D4A3G7", "type": "external" } ], "mass": 9543.0, "length": 87, "protein_name": "Keratin associated protein 7-1", "gene_name": "Krtap7-1", "organism": "Rat", "refseq_name": "keratin associated protein 7-1", "refseq_ac": [ { "id": "NP_001138474", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138474", "type": "external" } ], "gene_names_uniprotkb": "Krtap7-1", "gene_names_refseq": "Krtap7-1; RGD1560879", "protein_names_uniprotkb": "Keratin associated protein 7-1", "protein_names_refseq": "keratin associated protein 7-1", "tax_id": 10116, "disease": "", "pathway": " (rno:363741)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, 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"uniprot_id": [ { "id": "D4A3I2_RAT", "url": "https://www.uniprot.org/uniprot/D4A3I2", "type": "external" } ], "mass": 46152.0, "length": 417, "protein_name": "Similar to human chromosome 8 open reading frame 58", "gene_name": "C15h8orf58", "organism": "Rat", "refseq_name": "uncharacterized protein C8orf58 homolog isoform X2", "refseq_ac": [ { "id": "XP_063130502", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063130502", "type": "external" } ], "gene_names_uniprotkb": "C15h8orf58; RGD1308117", "gene_names_refseq": "C15h8orf58; RGD1308117", "protein_names_uniprotkb": "Similar to human chromosome 8 open reading frame 58", "protein_names_refseq": "uncharacterized protein C8orf58 homolog isoform X2", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 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"go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A3I2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A428-1", "uniprot_id": [ { "id": "D4A428_RAT", "url": "https://www.uniprot.org/uniprot/D4A428", "type": "external" } ], "mass": 21918.0, "length": 191, "protein_name": "Interferon, alpha 16-like 1", "gene_name": "Ifna16l1", "organism": "Rat", "refseq_name": "interferon, alpha 16-like 1 precursor", "refseq_ac": [ { "id": "NP_001395778", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001395778", "type": "external" } ], "gene_names_uniprotkb": "Ifna16l1; LOC134487075", "gene_names_refseq": "If1ai10; Ifna16l1; RGD1565225", "protein_names_uniprotkb": "Interferon, alpha 16-like 1", "protein_names_refseq": "interferon 1ai10; interferon alpha-1-like; interferon, alpha 16-like 1 precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:500491)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, 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"Dmrtb1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Dmrtb1", "gene_names_refseq": "", "protein_names_uniprotkb": "DMRT-like family B with proline-rich C-terminal, 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "primary ovarian insufficiency (Disease Ontology:DOID:5426)", "pathway": " (rno:313484)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0007548 sex differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A494-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A4I1-1", "uniprot_id": [ { "id": "D4A4I1_RAT", "url": "https://www.uniprot.org/uniprot/D4A4I1", "type": "external" } ], "mass": 36858.0, "length": 341, "protein_name": "C2 calcium-dependent domain containing 4D", "gene_name": "C2cd4d", "organism": "Rat", "refseq_name": "C2 calcium-dependent domain-containing protein 4D", "refseq_ac": [ { "id": "NP_001386656", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386656", "type": "external" } ], "gene_names_uniprotkb": "C2cd4d", "gene_names_refseq": "C2cd4d", "protein_names_uniprotkb": "C2 calcium-dependent domain containing 4D", "protein_names_refseq": "C2 calcium-dependent domain-containing protein 4D", "tax_id": 10116, "disease": "", "pathway": " (rno:100363111)", "pathway_count": 1, "publication_count": 0, "publication_id_list": 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"biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A4I1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A4L4-1", "uniprot_id": [ { "id": "MA7D2_RAT", "url": "https://www.uniprot.org/uniprot/D4A4L4", "type": "external" } ], "mass": 84875.0, "length": 763, "protein_name": "MAP7 domain-containing protein 2", "gene_name": "Map7d2", "organism": "Rat", "refseq_name": "MAP7 domain-containing protein 2", "refseq_ac": [ { "id": "NP_001276707", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001276707", "type": "external" } ], "gene_names_uniprotkb": "Map7d2; Brelin; Mtap7d2", "gene_names_refseq": "Brelin; Map7d2; Mtap7d2; RGD1564852", "protein_names_uniprotkb": "MAP7 domain-containing protein 2; Brain-enriched E-MAP-115-like protein", "protein_names_refseq": "MAP7 domain-containing protein 2; brain-enriched E-MAP-115-like protein", "tax_id": 10116, "disease": "", "pathway": " (rno:317508)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "22673903;29393594;30784582", "class_list": "", "function": "Microtubule-stabilizing protein involved in the control of cell motility and neurite outgrowth (By similarity). Acts as a critical cofactor for kinesin transport; in the proximal axon regulates kinesin-1 family members, KIF5A, KIF5B and KIF5C recruitment to microtubules and contributes to kinesin-1-mediated transport in the axons (PubMed:30784582)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "W0T3G7", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0019894 kinesin binding;GO:0140778 microtubule stabilizing activity", "go_cellular_component": "GO:0005813 centrosome;GO:0005874 microtubule;GO:0030424 axon;GO:0015630 microtubule cytoskeleton;GO:0043005 neuron projection", "go_biological_process": "GO:0000226 microtubule cytoskeleton organization;GO:0061564 axon development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D4A4L4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A4P4-1", "uniprot_id": [ { "id": "FAD1_RAT", "url": "https://www.uniprot.org/uniprot/D4A4P4", "type": "external" } ], "mass": 54604.0, "length": 490, "protein_name": "Bifunctional FAD diphosphatase/FAD synthase", "gene_name": "Flad1", "organism": "Rat", "refseq_name": "bifunctional FAD diphosphatase/FAD synthase", "refseq_ac": [ { "id": "NP_001103608", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103608", "type": "external" } ], "gene_names_uniprotkb": "Flad1", "gene_names_refseq": "Flad1", "protein_names_uniprotkb": "Bifunctional FAD diphosphatase/FAD synthase; FAD pyrophosphatase; FADHy; FADPPase; FMN adenylyltransferase; FMNAT; Flavin adenine dinucleotide synthase; NADH diphosphatase", "protein_names_refseq": "FAD synthase; FAD-synthetase; bifunctional FAD diphosphatase/FAD synthase", "tax_id": 10116, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (rno:751787); (R-RNO-196843)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "23946482;25954742;9211336", "class_list": "", "function": "This enzyme has two activities: FAD diphosphatase activity and FAD synthase activity (By similarity). FAD diphosphatase acts on FAD and NADH to produce FMN and NMNH(2-), respectively (By similarity). FAD synthase catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme (PubMed:9211336). In addition to its catalytic activities, the protein also facilitates the delivery of FAD to client apo-flavoproteins (By similarity). The balance between FAD synthesis and hydrolysis may be regulated by redox-sensing cysteine residues (By similarity). At a much lower rate, FAD synthase catalyzes the reverse pyrophosphorolytic reaction (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.22", "type": "external" }, { "id": "2.7.7.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.2", "type": "external" }, { "id": "3.6.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.18", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" } ], "go_molecular_function": "GO:0003919 FMN adenylyltransferase activity;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0035529 NADH pyrophosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005759 mitochondrial matrix;GO:0005829 cytosol", "go_biological_process": "GO:0006747 FAD biosynthetic process;GO:0006771 riboflavin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D4A4P4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A4Q2-1", "uniprot_id": [ { "id": "GP171_RAT", "url": "https://www.uniprot.org/uniprot/D4A4Q2", "type": "external" } ], "mass": 37405.0, "length": 326, "protein_name": "G protein-coupled receptor 171", "gene_name": "Gpr171", "organism": "Rat", "refseq_name": "G-protein coupled receptor 171", "refseq_ac": [ { "id": "NP_001383757", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383757", "type": "external" } ], "gene_names_uniprotkb": "Gpr171", "gene_names_refseq": "Gpr171", "protein_names_uniprotkb": "G protein-coupled receptor 171", "protein_names_refseq": "G-protein coupled receptor 171; probable G-protein coupled receptor 171", "tax_id": 10116, "disease": "", "pathway": " (rno:688737)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "24043826;29393594", "class_list": "", "function": "G protein-coupled receptor for Big LEN, a 16-amino acid neuropeptide produced from the precursor protein, proSAAS (encoded by PCSK1N) (PubMed:24043826). Acts through a G(i)-alpha-mediated pathway in response to Big LEN. Big LEN-GPR171 system plays an important role in regulating feeding and metabolism. Also plays a role in modulating fear and anxiety-like behaviors in the basolateral amygdala. Big LEN-GPR171 modulates the mu-type opioid receptor signaling and antinociception. Acts as a negative regulator T cell function (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008528 G protein-coupled peptide receptor activity;GO:0045028 G protein-coupled purinergic nucleotide receptor activity;GO:0008188 neuropeptide receptor activity;GO:0042923 neuropeptide binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0051930 regulation of sensory perception of pain;GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0060259 regulation of feeding behavior;GO:0045638 negative regulation of myeloid cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D4A4Q2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A4R3-1", "uniprot_id": [ { "id": "D4A4R3_RAT", "url": "https://www.uniprot.org/uniprot/D4A4R3", "type": "external" } ], "mass": 80237.0, "length": 735, "protein_name": "NUT family member 2", "gene_name": "Nutm2", "organism": "Rat", "refseq_name": "NUT family member 2F", "refseq_ac": [ { "id": "NP_001406684", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001406684", "type": "external" } ], "gene_names_uniprotkb": "Nutm2; Fam22f; Nutm2f", "gene_names_refseq": "Fam22f; Nutm2f; Nutm2; RGD1566043", "protein_names_uniprotkb": "NUT family member 2", "protein_names_refseq": "NUT family member 2F; family with sequence similarity 22, member F", "tax_id": 10116, "disease": "", "pathway": " (rno:306798)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A4R3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A4Y0-1", "uniprot_id": [ { "id": "D4A4Y0_RAT", "url": "https://www.uniprot.org/uniprot/D4A4Y0", "type": "external" } ], "mass": 26391.0, "length": 245, "protein_name": "Exosome complex component RRP41", "gene_name": "Exosc4", "organism": "Rat", "refseq_name": "exosome complex component RRP41", "refseq_ac": [ { "id": "NP_001128332", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128332", "type": "external" } ], "gene_names_uniprotkb": "Exosc4", "gene_names_refseq": "Exosc4", "protein_names_uniprotkb": "Exosome complex component RRP41; Exosome component 4; Ribosomal RNA-processing protein 41", "protein_names_refseq": "exosome complex component RRP41; exosome complex exonuclease RRP41", "tax_id": 10116, "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037)", "pathway": " (rno:300045); (R-RNO-429958); (R-RNO-450385); (R-RNO-450513); (R-RNO-450604); (R-RNO-6791226); (R-RNO-9930044)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0035925 mRNA 3'-UTR AU-rich region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0071028 nuclear mRNA surveillance;GO:0006396 RNA processing;GO:0030307 positive regulation of cell growth;GO:0051607 defense response to virus;GO:0000956 nuclear-transcribed mRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A4Y0-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A510-1", "uniprot_id": [ { "id": "D4A510_RAT", "url": "https://www.uniprot.org/uniprot/D4A510", "type": "external" } ], "mass": 135722.0, "length": 1247, "protein_name": "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2", "gene_name": "Smarcc2", "organism": "Rat", "refseq_name": "SWI/SNF complex subunit SMARCC2", "refseq_ac": [ { "id": "NP_001414181", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414181", "type": "external" } ], "gene_names_uniprotkb": "Smarcc2", "gene_names_refseq": "Smarcc2", "protein_names_uniprotkb": "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2", "protein_names_refseq": "SWI/SNF complex subunit SMARCC2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2", "tax_id": 10116, "disease": "opportunistic bacterial infectious disease (Disease Ontology:DOID:0050340); Coffin-Siris syndrome 8 (Disease Ontology:DOID:0112367); alcohol use disorder (Disease Ontology:DOID:1574); cancer (Disease Ontology:DOID:162); Coffin-Siris syndrome (Disease Ontology:DOID:1925)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0016514 SWI/SNF complex;GO:0071564 npBAF complex;GO:0071565 nBAF complex;GO:0031981 nuclear lumen", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A510-1", "record_type": "protein", "filter_code": "0000000.0000110.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A579-1", "uniprot_id": [ { "id": "D4A579_RAT", "url": "https://www.uniprot.org/uniprot/D4A579", "type": "external" } ], "mass": 58855.0, "length": 543, "protein_name": "Zinc finger and BTB domain-containing protein 7B", "gene_name": "Zbtb7b", "organism": "Rat", "refseq_name": "zinc finger and BTB domain-containing protein 7B isoform X2", "refseq_ac": [ { "id": "XP_006232676", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006232676", "type": "external" } ], "gene_names_uniprotkb": "Zbtb7b", "gene_names_refseq": "Zbtb7b; Zfp67", "protein_names_uniprotkb": "Zinc finger and BTB domain-containing protein 7B; Krueppel-related zinc finger protein cKrox; T-helper-inducing POZ/Krueppel-like factor; Zinc finger protein Th-POK", "protein_names_refseq": "zinc finger and BTB domain-containing protein 7B isoform X2", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:2000320 negative regulation of T-helper 17 cell differentiation;GO:0032740 positive regulation of interleukin-17 production;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A579-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A5H7-1", "uniprot_id": [ { "id": "D4A5H7_RAT", "url": "https://www.uniprot.org/uniprot/D4A5H7", "type": "external" } ], "mass": 41426.0, "length": 373, "protein_name": "Ataxin-7-like protein 3", "gene_name": "Atxn7l3", "organism": "Rat", "refseq_name": "ataxin-7-like protein 3 isoform X1", "refseq_ac": [ { "id": "XP_008766446", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008766446", "type": "external" } ], "gene_names_uniprotkb": "Atxn7l3; ATXN7L3", "gene_names_refseq": "Atxn7l3", "protein_names_uniprotkb": "Ataxin-7-like protein 3; SAGA-associated factor 11 homolog", "protein_names_refseq": "ataxin-7-like protein 3 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:287734)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex. Regulates H2B monoubiquitination (H2Bub1) levels. Affects subcellular distribution of ENY2, USP22 and ATXN7L3B., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0071819 DUBm complex;GO:0000124 SAGA complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A5H7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A5L9-1", "uniprot_id": [ { "id": "D4A5L9_RAT", "url": "https://www.uniprot.org/uniprot/D4A5L9", "type": "external" } ], "mass": 11635.0, "length": 105, "protein_name": "Cytochrome c, somatic like 2", "gene_name": "Cycsl2", "organism": "Rat", "refseq_name": "cytochrome c, somatic-like", "refseq_ac": [ { "id": "XP_038943755", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038943755", "type": "external" } ], "gene_names_uniprotkb": "Cycsl2; AC128290.1; LOC690675", "gene_names_refseq": "Cycsl2", "protein_names_uniprotkb": "Cytochrome c, somatic like 2", "protein_names_refseq": "cytochrome c, somatic-like", "tax_id": 10116, "disease": "Huntington's disease (Disease Ontology:DOID:12858); thrombocytopenia (Disease Ontology:DOID:1588); pancreatic cancer (Disease Ontology:DOID:1793); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); hyperglycemia (Disease Ontology:DOID:4195); cholangiocarcinoma (Disease Ontology:DOID:4947)", "pathway": " (rno:690675); (R-RNO-111457); (R-RNO-111458); (R-RNO-111459); (R-RNO-111461); (R-RNO-2151201); (R-RNO-3299685); (R-RNO-5620971); (R-RNO-5628897); (R-RNO-611105); (R-RNO-9627069); (R-RNO-9707564)", "pathway_count": 12, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain., [UniProtKB, UniProtKB, UniProtKB]; Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0020037 heme binding", "go_cellular_component": "GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0006915 apoptotic process;GO:0006123 mitochondrial electron transport, cytochrome c to oxygen;GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A5L9-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A5N4-1", "uniprot_id": [ { "id": "D4A5N4_RAT", "url": "https://www.uniprot.org/uniprot/D4A5N4", "type": "external" } ], "mass": 37945.0, "length": 345, "protein_name": "DNA repair protein", "gene_name": "Xrcc3", "organism": "Rat", "refseq_name": "DNA repair protein XRCC3", "refseq_ac": [ { "id": "NP_001414349", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414349", "type": "external" } ], "gene_names_uniprotkb": "Xrcc3", "gene_names_refseq": "Xrcc3", "protein_names_uniprotkb": "DNA repair protein", "protein_names_refseq": "DNA repair protein XRCC3; X-ray repair complementing defective repair in Chinese hamster cells 3; rCG27697-like", "tax_id": 10116, "disease": "brain glioma (Disease Ontology:DOID:0060108); hypertension (Disease Ontology:DOID:10763); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); high grade glioma (Disease Ontology:DOID:3070); coronary artery disease (Disease Ontology:DOID:3393); meningioma (Disease Ontology:DOID:3565); central nervous system cancer (Disease Ontology:DOID:3620); myocardial infarction (Disease Ontology:DOID:5844); familial melanoma (Disease Ontology:DOID:6846); multiple myeloma (Disease Ontology:DOID:9538)", "pathway": " (rno:102551085); (R-RNO-5685942); (R-RNO-5693537); (R-RNO-5693568); (R-RNO-5693579)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0000400 four-way junction DNA binding;GO:0008821 crossover junction DNA endonuclease activity;GO:0140664 ATP-dependent DNA damage sensor activity;GO:0003677 DNA binding", "go_cellular_component": "GO:0043596 nuclear replication fork;GO:0033065 Rad51C-XRCC3 complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0010824 regulation of centrosome duplication;GO:0006281 DNA repair;GO:0000724 double-strand break repair via homologous recombination;GO:0036297 interstrand cross-link repair;GO:0090656 t-circle formation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A5N4-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A5N7-1", "uniprot_id": [ { "id": "D4A5N7_RAT", "url": "https://www.uniprot.org/uniprot/D4A5N7", "type": "external" } ], "mass": 18618.0, "length": 163, "protein_name": "Small ribosomal subunit protein eS10", "gene_name": "Rps10l2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rps10l2; AABR07024954.1; RGD1559708", "gene_names_refseq": "", "protein_names_uniprotkb": "Small ribosomal subunit protein eS10; 40S ribosomal protein S10", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the 40S ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005730 nucleolus;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A5N7-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A651-1", "uniprot_id": [ { "id": "D4A651_RAT", "url": "https://www.uniprot.org/uniprot/D4A651", "type": "external" } ], "mass": 103712.0, "length": 919, "protein_name": "PMS1 homolog 1, mismatch repair system component", "gene_name": "Pms1", "organism": "Rat", "refseq_name": "PMS1 protein homolog 1 isoform X1", "refseq_ac": [ { "id": "XP_038939969", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038939969", "type": "external" } ], "gene_names_uniprotkb": "Pms1", "gene_names_refseq": "Pms1", "protein_names_uniprotkb": "PMS1 homolog 1, mismatch repair system component", "protein_names_refseq": "PMS1 protein homolog 1 isoform X1", "tax_id": 10116, "disease": "polymyositis (Disease Ontology:DOID:0080745); dermatomyositis (Disease Ontology:DOID:10223); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); Lynch syndrome (Disease Ontology:DOID:3883)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0019899 enzyme binding;GO:0016887 ATP hydrolysis activity;GO:0030983 mismatched DNA binding;GO:0140664 ATP-dependent DNA damage sensor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0032300 mismatch repair complex;GO:0032390 MutLbeta complex", "go_biological_process": "GO:0006298 mismatch repair;GO:0009410 response to xenobiotic stimulus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A651-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A6T0-1", "uniprot_id": [ { "id": "D4A6T0_RAT", "url": "https://www.uniprot.org/uniprot/D4A6T0", "type": "external" } ], "mass": 61463.0, "length": 536, "protein_name": "Flavin-containing monooxygenase", "gene_name": "Fmo13", "organism": "Rat", "refseq_name": "flavin-containing monooxygenase 5", "refseq_ac": [ { "id": "XP_008767949", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008767949", "type": "external" } ], "gene_names_uniprotkb": "Fmo13", "gene_names_refseq": "Fmo13", "protein_names_uniprotkb": "Flavin-containing monooxygenase; 1.-.-.-", "protein_names_refseq": "flavin-containing monooxygenase 5", "tax_id": 10116, "disease": "chromosome 1q21.1 deletion syndrome (Disease Ontology:DOID:0060411)", "pathway": " (rno:289193)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics. Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes. In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "1.14.13.148", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.148", "type": "external" }, { "id": "1.14.13.8", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.8", "type": "external" }, { "id": "1.6.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.3.1", "type": "external" }, { "id": "1.14.13.32", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.32", "type": "external" } ], "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0034899 trimethylamine monooxygenase activity;GO:0050661 NADP binding;GO:0004499 N,N-dimethylaniline monooxygenase activity;GO:0047822 hypotaurine monooxygenase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A6T0-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A740-1", "uniprot_id": [ { "id": "D4A740_RAT", "url": "https://www.uniprot.org/uniprot/D4A740", "type": "external" } ], "mass": 106479.0, "length": 949, "protein_name": "Interleukin-17 receptor A", "gene_name": "Il17ra", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Il17ra", "gene_names_refseq": "", "protein_names_uniprotkb": "Interleukin-17 receptor A", "protein_names_refseq": "", "tax_id": 10116, "disease": "immunodeficiency 51 (Disease Ontology:DOID:0111996)", "pathway": " (rno:312679)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "(Microbial infection) Receptor for SARS coronavirus-2/SARS-CoV-2 virus protein ORF8, leading to IL17 pathway activation and an increased secretion of pro-inflammatory factors through activating NF-kappa-B signaling pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0030368 interleukin-17 receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0032736 positive regulation of interleukin-13 production;GO:0032754 positive regulation of interleukin-5 production;GO:0032747 positive regulation of interleukin-23 production;GO:0032755 positive regulation of interleukin-6 production;GO:0009615 response to virus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A740-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A7E4-1", "uniprot_id": [ { "id": "D4A7E4_RAT", "url": "https://www.uniprot.org/uniprot/D4A7E4", "type": "external" } ], "mass": 55657.0, "length": 505, "protein_name": "Protein kinase AMP-activated non-catalytic subunit gamma 3", "gene_name": "Prkag3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Prkag3", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein kinase AMP-activated non-catalytic subunit gamma 3", "protein_names_refseq": "", "tax_id": 10116, "disease": "lethal congenital glycogen storage disease of heart (Disease Ontology:DOID:0090101); neurodegenerative disease (Disease Ontology:DOID:1289); Wolff-Parkinson-White syndrome (Disease Ontology:DOID:384)", "pathway": " (rno:301518); (R-RNO-1632852); (R-RNO-380972); (R-RNO-5628897); (R-RNO-6804756); (R-RNO-9931269)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 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Can also be active at the cell surface of specialized cells, e.g., in the inner ear hair bundles uses the high K(+) of the endolymph to regulate intracellular pH (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; The SLC9A9 gene sequence and expression profile in prefrontal cortex, dorsal striatum and hippocampus in two genetic rat models of attention deficit hyperactivity disorder, were examined., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015385 sodium:proton antiporter activity;GO:0015386 potassium:proton antiporter activity", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0055037 recycling endosome;GO:0031902 late endosome membrane;GO:0030670 phagocytic vesicle membrane", "go_biological_process": "GO:0090382 phagosome maturation;GO:0042742 defense response to bacterium;GO:0035725 sodium ion transmembrane transport;GO:0051453 regulation of intracellular pH;GO:0071805 potassium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D4A7H1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A7N5-1", "uniprot_id": [ { "id": "D4A7N5_RAT", "url": "https://www.uniprot.org/uniprot/D4A7N5", "type": "external" } ], "mass": 35280.0, "length": 313, "protein_name": "Olfactory receptor", "gene_name": "Or52h9", "organism": "Rat", "refseq_name": "olfactory receptor Olr152", "refseq_ac": [ { "id": "NP_001000546", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000546", "type": "external" } ], "gene_names_uniprotkb": "Or52h9", "gene_names_refseq": "Olr152; Or52h9; ratchr1-162297320-162298261_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 152; olfactory receptor Olr152; olfactory receptor gene Olr152", "tax_id": 10116, "disease": "", "pathway": " (rno:365332)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A7N5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A7N7-1", "uniprot_id": [ { "id": "D4A7N7_RAT", "url": "https://www.uniprot.org/uniprot/D4A7N7", "type": "external" } ], "mass": 70017.0, "length": 604, "protein_name": "Tetratricopeptide repeat domain 39D", "gene_name": "Ttc39d", "organism": "Rat", "refseq_name": "tetratricopeptide repeat domain 39D", "refseq_ac": [ { "id": "NP_001178835", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178835", "type": "external" } ], "gene_names_uniprotkb": "Ttc39d", "gene_names_refseq": "RGD1311615; Ttc39d", "protein_names_uniprotkb": "Tetratricopeptide repeat domain 39D", "protein_names_refseq": "tetratricopeptide repeat domain 39D", "tax_id": 10116, "disease": "", "pathway": " (rno:366531)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0090181 regulation of cholesterol metabolic process;GO:0010887 negative regulation of cholesterol storage;GO:0042632 cholesterol homeostasis;GO:0010874 regulation of cholesterol efflux", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A7N7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A7R5-1", "uniprot_id": [ { "id": "D4A7R5_RAT", "url": "https://www.uniprot.org/uniprot/D4A7R5", "type": "external" } ], "mass": 68630.0, "length": 618, "protein_name": "Ovochymase 2", "gene_name": "Ovch2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ovch2", "gene_names_refseq": "", "protein_names_uniprotkb": "Ovochymase 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "", "go_biological_process": "GO:0006508 proteolysis;GO:0009566 fertilization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A7R5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A7Z2-1", "uniprot_id": [ { "id": "D4A7Z2_RAT", "url": "https://www.uniprot.org/uniprot/D4A7Z2", "type": "external" } ], "mass": 11115.0, "length": 97, "protein_name": "Ribosomal protein L37", "gene_name": "Rpl37-ps1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rpl37-ps1", "gene_names_refseq": "", "protein_names_uniprotkb": "Ribosomal protein L37", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0019843 rRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A7Z2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A7Z6-1", "uniprot_id": [ { "id": "D4A7Z6_RAT", "url": "https://www.uniprot.org/uniprot/D4A7Z6", "type": "external" } ], "mass": 239456.0, "length": 2155, "protein_name": "Alpha-tectorin", "gene_name": "Tecta", "organism": "Rat", "refseq_name": "alpha-tectorin isoform 2 precursor", "refseq_ac": [ { "id": "NP_001100284", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100284", "type": "external" } ], "gene_names_uniprotkb": "Tecta", "gene_names_refseq": "Tecta", "protein_names_uniprotkb": "Alpha-tectorin", "protein_names_refseq": "alpha-tectorin isoform 2 precursor; alpha-tectorin", "tax_id": 10116, "disease": "autosomal recessive nonsyndromic deafness 21 (Disease Ontology:DOID:0110479); autosomal dominant nonsyndromic deafness 12 (Disease Ontology:DOID:0110544); sensorineural hearing loss (Disease Ontology:DOID:10003)", "pathway": " (rno:300653); (R-RNO-163125)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "One of the major non-collagenous components of the tectorial membrane. 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RGD1565360", "protein_names_uniprotkb": "Holocarboxylase synthetase", "protein_names_refseq": "biotin--protein ligase isoform X1", "tax_id": 10116, "disease": "holocarboxylase synthetase deficiency (Disease Ontology:DOID:859)", "pathway": " (rno:288240); (R-RNO-196780)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019899 enzyme binding;GO:0042802 identical protein binding;GO:0009374 biotin binding;GO:0004077 biotin--[biotin carboxyl-carrier protein] ligase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016363 nuclear matrix;GO:0000785 chromatin;GO:0005652 nuclear lamina;GO:0005737 cytoplasm", "go_biological_process": "GO:0043687 post-translational protein modification;GO:0006768 biotin metabolic process;GO:0070781 response to biotin", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AA38-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AA43-1", "uniprot_id": [ { "id": "D4AA43_RAT", "url": "https://www.uniprot.org/uniprot/D4AA43", "type": "external" } ], "mass": 69607.0, "length": 621, "protein_name": "Kelch-like family member 40", "gene_name": "Klhl40", "organism": "Rat", "refseq_name": "kelch-like protein 40", "refseq_ac": [ { "id": "NP_001101665", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101665", "type": "external" } ], "gene_names_uniprotkb": "Klhl40", "gene_names_refseq": "Kbtbd5; Klhl40", "protein_names_uniprotkb": "Kelch-like family member 40", "protein_names_refseq": "kelch repeat and BTB (POZ) domain containing 5; kelch repeat and BTB domain-containing protein 5; kelch-like 40; kelch-like protein 40", "tax_id": 10116, "disease": "nemaline myopathy 8 (Disease Ontology:DOID:0110930)", "pathway": " (rno:316088)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development. The BCR(KLHL40) complex acts by mediating ubiquitination and degradation of TFDP1, thereby regulating the activity of the E2F:DP transcription factor complex. Promotes stabilization of LMOD3 by acting as a negative regulator of LMOD3 ubiquitination; the molecular process by which it negatively regulates ubiquitination of LMOD3 is however unclear., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031674 I band;GO:0031672 A band;GO:0031463 Cul3-RING ubiquitin ligase complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0048741 skeletal muscle fiber development;GO:0031398 positive regulation of protein ubiquitination;GO:0031397 negative regulation of protein ubiquitination;GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AA43-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AA47-1", "uniprot_id": [ { "id": "AT8B1_RAT", "url": "https://www.uniprot.org/uniprot/D4AA47", "type": "external" } ], "mass": 143834.0, "length": 1251, "protein_name": "Phospholipid-transporting ATPase IC", "gene_name": "Atp8b1", "organism": "Rat", "refseq_name": "phospholipid-transporting ATPase IC", "refseq_ac": [ { "id": "NP_001424194", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001424194", "type": "external" } ], "gene_names_uniprotkb": "Atp8b1", "gene_names_refseq": "Atp8b1", "protein_names_uniprotkb": "Phospholipid-transporting ATPase IC; 7.6.2.1; ATPase class I type 8B member 1; P4-ATPase flippase complex alpha subunit ATP8B1", "protein_names_refseq": "ATPase, Class I, type 8B, member 1; ATPase, aminophospholipid transporter, class I, type 8B, member 1; P4-ATPase flippase complex alpha subunit ATP8B1; phospholipid-transporting ATPase IC; probable phospholipid-transporting ATPase IC", "tax_id": 10116, "disease": "progressive familial intrahepatic cholestasis 1 (Disease Ontology:DOID:0070226); intrahepatic cholestasis of pregnancy 1 (Disease Ontology:DOID:0070228); benign recurrent intrahepatic cholestasis 1 (Disease Ontology:DOID:0070231); intrahepatic cholestasis (Disease Ontology:DOID:1852)", "pathway": " (rno:291555); (R-RNO-936837)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "19027009;22673903;24643366;26240149", "class_list": "", "function": "ATP8B1, a P-type aminophospholipid translocase, is enriched in cerebral microvessels and may have a role in plasma membrane lipid transport, [RefSeq, PubMed]; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of phospholipids, in particular phosphatidylcholines (PC), from the outer to the inner leaflet of the plasma membrane (By similarity) (PubMed:19027009). May participate in the establishment of the canalicular membrane integrity by ensuring asymmetric distribution of phospholipids in the canicular membrane. Thus may have a role in the regulation of bile acids transport into the canaliculus, uptake of bile acids from intestinal contents into intestinal mucosa or both and protect hepatocytes from bile salts (PubMed:19027009). Involved in the microvillus formation in polarized epithelial cells; the function seems to be independent from its flippase activity. Participates in correct apical membrane localization of CDC42, CFTR and SLC10A2 (By similarity). Enables CDC42 clustering at the apical membrane during enterocyte polarization through the interaction between CDC42 polybasic region and negatively charged membrane lipids provided by ATP8B1 (By similarity). Together with TMEM30A is involved in uptake of the synthetic drug alkylphospholipid perifosine (By similarity). Required for the preservation of cochlear hair cells in the inner ear. May act as cardiolipin transporter during inflammatory injury (By similarity)., [UniProtKB, PubMed, UniProtKB, UniProtKB]; The predominant P4 ATPases in pure pancreatic beta cells and human and rat pancreatic islets were ATP8B1, ATP8B2, and ATP9A. ATP8B1 and CDC50A were highly concentrated in ISG, [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "7.6.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.1", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005319 lipid transporter activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0090554 phosphatidylcholine floppase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0016324 apical plasma membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0015721 bile acid and bile salt transport;GO:0045892 negative regulation of DNA-templated transcription;GO:0045332 phospholipid translocation;GO:0015711 organic anion transport;GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "D4AA47-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AA59-1", "uniprot_id": [ { "id": "D4AA59_RAT", "url": "https://www.uniprot.org/uniprot/D4AA59", "type": "external" } ], "mass": 49205.0, "length": 426, "protein_name": "Zinc finger CCCH domain-containing protein 15", "gene_name": "Zc3h15l1", "organism": "Rat", "refseq_name": "zinc finger CCCH domain-containing protein 15-like", "refseq_ac": [ { "id": "XP_038952304", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038952304", "type": "external" } ], "gene_names_uniprotkb": "Zc3h15l1; AC115670.2; RGD1564243", "gene_names_refseq": "Zc3h15l1", "protein_names_uniprotkb": "Zinc finger CCCH domain-containing protein 15", "protein_names_refseq": "zinc finger CCCH domain-containing protein 15-like", "tax_id": 10116, "disease": "", "pathway": " (rno:291174)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AA59-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AA61-1", "uniprot_id": [ { "id": "D4AA61_RAT", "url": "https://www.uniprot.org/uniprot/D4AA61", "type": "external" } ], "mass": 48103.0, "length": 422, "protein_name": "Lipase", "gene_name": "Lipm", "organism": "Rat", "refseq_name": "lipase member M precursor", "refseq_ac": [ { "id": "NP_001419222", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001419222", "type": "external" } ], "gene_names_uniprotkb": "Lipm", "gene_names_refseq": "Lipl3; 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3.4.19.12", "protein_names_refseq": "", "tax_id": 10116, "disease": "chromosome 15q13.3 microdeletion syndrome (Disease Ontology:DOID:0060394)", "pathway": " (rno:309252); (R-RNO-5689896)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0035871 protein K11-linked deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4ABZ4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AC18-1", "uniprot_id": [ { "id": "D4AC18_RAT", "url": "https://www.uniprot.org/uniprot/D4AC18", "type": "external" } ], "mass": 34874.0, "length": 309, "protein_name": "Olfactory receptor", "gene_name": "Or7e171d", "organism": "Rat", "refseq_name": "olfactory receptor Olr1162", "refseq_ac": [ { "id": "NP_001000870", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000870", "type": "external" } ], "gene_names_uniprotkb": "Or7e171d", "gene_names_refseq": "Olr1162; Or7e171d", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1162; olfactory receptor Olr1162; olfactory receptor gene Olr1162", "tax_id": 10116, "disease": "", "pathway": " (rno:405167)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AC18-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AC36-1", "uniprot_id": [ { "id": "D4AC36_RAT", "url": "https://www.uniprot.org/uniprot/D4AC36", "type": "external" } ], "mass": 37997.0, "length": 361, "protein_name": "Eukaryotic translation initiation factor 3 subunit F", "gene_name": "Eif3f", "organism": "Rat", "refseq_name": "eukaryotic translation initiation factor 3 subunit F", "refseq_ac": [ { "id": "NP_001264231", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264231", "type": "external" } ], "gene_names_uniprotkb": "Eif3f; EIF3F; EIF3S5", "gene_names_refseq": "Eif3f; Eif3s5", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit F; Eukaryotic translation initiation factor 3 subunit 5; eIF-3-epsilon; eIF3 p47; eIF3f", "protein_names_refseq": "eukaryotic translation initiation factor 3 subunit F; eukaryotic translation initiation factor 3, subunit 5 (epsilon)", "tax_id": 10116, "disease": "autosomal recessive intellectual developmental disorder 67 (Disease Ontology:DOID:0081228); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (rno:293427); (R-RNO-156827); (R-RNO-72649); (R-RNO-72689); (R-RNO-72695); (R-RNO-72702)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression., [UniProtKB, HAMAP]; Deubiquitinates activated NOTCH1, promoting its nuclear import, thereby acting as a positive regulator of Notch signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0003743 translation initiation factor activity;GO:0004843 cysteine-type deubiquitinase activity;GO:0031369 translation initiation factor binding;GO:0140492 metal-dependent deubiquitinase activity", "go_cellular_component": "GO:0045202 synapse;GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m;GO:0005852 eukaryotic translation initiation factor 3 complex", "go_biological_process": "GO:0075522 IRES-dependent viral translational initiation;GO:0006413 translational initiation;GO:0001732 formation of cytoplasmic translation initiation complex", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AC36-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ACA2-1", "uniprot_id": [ { "id": "D4ACA2_RAT", "url": "https://www.uniprot.org/uniprot/D4ACA2", "type": "external" } ], "mass": 22917.0, "length": 214, "protein_name": "Methyltransferase HEMK2", "gene_name": "Hemk2", "organism": "Rat", "refseq_name": "methyltransferase N6AMT1", "refseq_ac": [ { "id": "NP_001178521", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178521", "type": "external" } ], "gene_names_uniprotkb": "Hemk2; N6amt1", "gene_names_refseq": "Hemk2; N6amt1; RGD1311843", "protein_names_uniprotkb": "Methyltransferase HEMK2; HemK methyltransferase family member 2; Lysine N-methyltransferase 9; Methylarsonite methyltransferase N6AMT1; Methyltransferase N6AMT1; Protein N(5)-glutamine methyltransferase", "protein_names_refseq": "HemK methyltransferase family member 2; N(6)-adenine-specific DNA methyltransferase 1; N-6 adenine-specific DNA methyltransferase 1 (putative); methyltransferase N6AMT1", "tax_id": 10116, "disease": "", "pathway": " (rno:288309)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Methyltransferase that can methylate proteins and, to a lower extent, arsenic. Catalytic subunit of a heterodimer with TRMT112, which monomethylates 'Lys-12' of histone H4 (H4K12me1), a modification present at the promoters of numerous genes encoding cell cycle regulators. Catalytic subunit of a heterodimer with TRMT112, which catalyzes N5-methylation of Glu residue of proteins with a Gly-Gln-Xaa-Xaa-Xaa-Arg motif. Methylates ETF1 on 'Gln-185'; ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. May also play a role in the modulation of arsenic-induced toxicity by mediating the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid. It however only plays a limited role in arsenic metabolism compared with AS3MT., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.355", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355", "type": "external" } ], "go_molecular_function": "GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity;GO:0003676 nucleic acid binding;GO:0008276 protein methyltransferase activity;GO:0008757 S-adenosylmethionine-dependent methyltransferase activity;GO:0030791 arsenite methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0035097 histone methyltransferase complex;GO:0032991 protein-containing complex;GO:0035657 eRF1 methyltransferase complex", "go_biological_process": "GO:0030307 positive regulation of cell growth;GO:0045815 transcription initiation-coupled chromatin remodeling;GO:0009404 toxin metabolic process;GO:0045814 negative regulation of gene expression, epigenetic;GO:0018872 arsonoacetate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ACA2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ACI5-1", "uniprot_id": [ { "id": "D4ACI5_RAT", "url": "https://www.uniprot.org/uniprot/D4ACI5", "type": "external" } ], "mass": 26546.0, "length": 227, "protein_name": "RIKEN cDNA A630001G21 gene like", "gene_name": "A630001G21Rikl", "organism": "Rat", "refseq_name": "nuclear autoantigen Sp-100 isoform X1", "refseq_ac": [ { "id": "XP_056840602", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_056840602", "type": "external" } ], "gene_names_uniprotkb": "A630001G21Rikl; RGD1563917", "gene_names_refseq": "A630001G21Rikl", "protein_names_uniprotkb": "RIKEN cDNA A630001G21 gene like", "protein_names_refseq": "nuclear autoantigen Sp-100 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:501176)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4ACI5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ACK1-1", "uniprot_id": [ { "id": "D4ACK1_RAT", "url": "https://www.uniprot.org/uniprot/D4ACK1", "type": "external" } ], "mass": 219667.0, "length": 2143, "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "Nup214", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Nup214", "gene_names_refseq": "", "protein_names_uniprotkb": "Nuclear pore complex protein Nup214; 214 kDa nucleoporin; Nucleoporin Nup214", "protein_names_refseq": "", "tax_id": 10116, "disease": "acute myeloid leukemia (Disease Ontology:DOID:9119); brain disease (Disease Ontology:DOID:936); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (R-RNO-159227); (R-RNO-159230); (R-RNO-159231); (R-RNO-159236); (R-RNO-170822); (R-RNO-1855170); (R-RNO-1855196); (R-RNO-1855229); (R-RNO-191859); (R-RNO-3108214); (R-RNO-3232142); (R-RNO-3301854); (R-RNO-3371453); (R-RNO-4085377); (R-RNO-450520); (R-RNO-4551638); (R-RNO-4570464); (R-RNO-4615885)", "pathway_count": 18, "publication_count": 2, "publication_id_list": "22673903;38843836", "class_list": "", "function": "Part of the nuclear pore complex. Has a critical role in nucleocytoplasmic transport. May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 8, "predicted_n_glycosites": 0, "predicted_o_glycosites": 8, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017056 structural constituent of nuclear pore;GO:0008139 nuclear localization sequence binding;GO:0005049 nuclear export signal receptor activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005643 nuclear pore;GO:1990876 cytoplasmic side of nuclear pore;GO:0005634 nucleus", "go_biological_process": "GO:0006406 mRNA export from nucleus;GO:0046822 regulation of nucleocytoplasmic transport;GO:0006611 protein export from nucleus;GO:0051726 regulation of cell cycle;GO:0006405 RNA export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "D4ACK1-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ACL4-1", "uniprot_id": [ { "id": "D4ACL4_RAT", "url": "https://www.uniprot.org/uniprot/D4ACL4", "type": "external" } ], "mass": 30308.0, "length": 280, "protein_name": "Homeo box C12", "gene_name": "Hoxc12", "organism": "Rat", "refseq_name": "homeobox protein Hox-C12", "refseq_ac": [ { "id": "NP_001100266", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100266", "type": "external" } ], "gene_names_uniprotkb": "Hoxc12", "gene_names_refseq": "Hoxc12", "protein_names_uniprotkb": "Homeo box C12", "protein_names_refseq": "homeobox protein Hox-C12", "tax_id": 10116, "disease": "", "pathway": " (rno:300262)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ACL4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ACN9-1", "uniprot_id": [ { "id": "D4ACN9_RAT", "url": "https://www.uniprot.org/uniprot/D4ACN9", "type": "external" } ], "mass": 34267.0, "length": 311, "protein_name": "Solute carrier family 25 member 36", "gene_name": "Slc25a36l1; Slc25a36", "organism": "Rat", "refseq_name": "solute carrier family 25 member 36", "refseq_ac": [ { "id": "NP_001414658", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414658", "type": "external" } ], "gene_names_uniprotkb": "Slc25a36l1; Slc25a36; Slc25a36", "gene_names_refseq": "Slc25a36", "protein_names_uniprotkb": "Solute carrier family 25 member 36", "protein_names_refseq": "solute carrier family 25 (pyrimidine nucleotide carrier), member 36; solute carrier family 25 member 36", "tax_id": 10116, "disease": "familial hyperinsulinemic hypoglycemia 8 (Disease Ontology:DOID:0081328)", "pathway": " (rno:501039)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015218 pyrimidine nucleotide transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:1990519 pyrimidine nucleotide import into mitochondrion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ACN9-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ACZ6-1", "uniprot_id": [ { "id": "D4ACZ6_RAT", "url": "https://www.uniprot.org/uniprot/D4ACZ6", "type": "external" } ], "mass": 36551.0, "length": 323, "protein_name": "Olfactory receptor", "gene_name": "Or52s20", "organism": "Rat", "refseq_name": "olfactory receptor Olr94", "refseq_ac": [ { "id": "NP_001001023", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001023", "type": "external" } ], "gene_names_uniprotkb": "Or52s20", "gene_names_refseq": "Olr94; Or52s20", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 94; olfactory receptor Olr94; olfactory receptor gene Olr94", "tax_id": 10116, "disease": "", "pathway": " (rno:405908)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ACZ6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ADD4-1", "uniprot_id": [ { "id": "D4ADD4_RAT", "url": "https://www.uniprot.org/uniprot/D4ADD4", "type": "external" } ], "mass": 189732.0, "length": 1705, "protein_name": "ADAMTS-like 3", "gene_name": "Adamtsl3", "organism": "Rat", "refseq_name": "ADAMTS-like protein 3", "refseq_ac": [ { "id": "NP_001101003", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101003", "type": "external" } ], "gene_names_uniprotkb": "Adamtsl3", "gene_names_refseq": "Adamtsl3", "protein_names_uniprotkb": "ADAMTS-like 3", "protein_names_refseq": "ADAMTS-like protein 3", "tax_id": 10116, "disease": "", "pathway": " (rno:308787); (R-RNO-5173214)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0031012 extracellular matrix;GO:0005576 extracellular region", "go_biological_process": "GO:0030198 extracellular matrix organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ADD4-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ADJ5-1", "uniprot_id": [ { "id": "D4ADJ5_RAT", "url": "https://www.uniprot.org/uniprot/D4ADJ5", "type": "external" } ], "mass": 31021.0, "length": 277, "protein_name": "Hairy and enhancer of split-related protein HELT", "gene_name": "Helt", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Helt; 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alcohol dependence (Disease Ontology:DOID:0050741); renal fibrosis (Disease Ontology:DOID:0050855); ileitis (Disease Ontology:DOID:0060189); atrial fibrillation (Disease Ontology:DOID:0060224); mastoiditis (Disease Ontology:DOID:0060322); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); meningococcal meningitis (Disease Ontology:DOID:0080176); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); urinary tract infection (Disease Ontology:DOID:0080784); acute necrotizing pancreatitis (Disease Ontology:DOID:0080998); hymenolepiasis (Disease Ontology:DOID:10074); dry eye syndrome (Disease Ontology:DOID:10140); dermatomyositis (Disease Ontology:DOID:10223); leprosy (Disease Ontology:DOID:1024); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); kidney failure (Disease Ontology:DOID:1074); otitis media (Disease Ontology:DOID:10754); Kuhnt-Junius degeneration (Disease Ontology:DOID:10873); cholesteatoma of middle ear (Disease Ontology:DOID:10964); urinary bladder cancer (Disease Ontology:DOID:11054); anogenital venereal wart (Disease Ontology:DOID:11168); suppurative otitis media (Disease Ontology:DOID:11506); alveolar echinococcosis (Disease Ontology:DOID:12148); vitiligo (Disease Ontology:DOID:12306); carotid stenosis (Disease Ontology:DOID:13001); Behcet's disease (Disease Ontology:DOID:13241); pulmonary sarcoidosis (Disease Ontology:DOID:13406); familial combined hyperlipidemia (Disease Ontology:DOID:13809); alcoholic liver cirrhosis (Disease Ontology:DOID:14018); anterior uveitis (Disease Ontology:DOID:1407); cystic echinococcosis (Disease Ontology:DOID:1495); alcohol use disorder (Disease Ontology:DOID:1574); diffuse scleroderma (Disease Ontology:DOID:1580); breast cancer (Disease Ontology:DOID:1612); transient cerebral ischemia (Disease Ontology:DOID:224); asthma (Disease Ontology:DOID:2841); severe acute respiratory syndrome (Disease Ontology:DOID:2945); pulmonary tuberculosis (Disease Ontology:DOID:2957); skin papilloma (Disease Ontology:DOID:3178); atopic dermatitis (Disease Ontology:DOID:3310); middle cerebral artery infarction (Disease Ontology:DOID:3525); tuberculosis (Disease Ontology:DOID:399); glucose metabolism disease (Disease Ontology:DOID:4194); allergic rhinitis (Disease Ontology:DOID:4481); rhinitis (Disease Ontology:DOID:4483); keratitis (Disease Ontology:DOID:4677); pancreatitis (Disease Ontology:DOID:4989); eye disease (Disease Ontology:DOID:5614); uric acid nephrolithiasis (Disease Ontology:DOID:580); primary immunodeficiency disease (Disease Ontology:DOID:612); acne (Disease Ontology:DOID:6543); hepatocellular carcinoma (Disease Ontology:DOID:684); end stage renal disease (Disease Ontology:DOID:783); peritonitis (Disease Ontology:DOID:8283); lung disease (Disease Ontology:DOID:850); gastroesophageal reflux disease (Disease Ontology:DOID:8534); collagen disease (Disease Ontology:DOID:854); perinatal necrotizing enterocolitis (Disease Ontology:DOID:8677); cholesteatoma (Disease Ontology:DOID:869); bacterial pneumonia (Disease Ontology:DOID:874); seborrheic dermatitis (Disease Ontology:DOID:8741); molluscum contagiosum (Disease Ontology:DOID:8867); psoriasis (Disease Ontology:DOID:8893); cutaneous leishmaniasis (Disease Ontology:DOID:9111); colorectal cancer (Disease Ontology:DOID:9256); type 2 diabetes mellitus (Disease Ontology:DOID:9352); keratoconjunctivitis (Disease Ontology:DOID:9368); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (R-RNO-1461957); (R-RNO-5686938); (R-RNO-6798695)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 70, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042497 triacyl lipopeptide binding;GO:0004888 transmembrane signaling receptor activity;GO:0038023 signaling receptor activity;GO:0042834 peptidoglycan binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex;GO:0045121 membrane raft;GO:0030670 phagocytic vesicle membrane;GO:0005737 cytoplasm", "go_biological_process": "GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0001819 positive regulation of cytokine production;GO:0002224 toll-like receptor signaling pathway;GO:0032680 regulation of tumor necrosis factor production", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PTD9-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "E9PTF0-1", "uniprot_id": [ { "id": "E9PTF0_RAT", "url": "https://www.uniprot.org/uniprot/E9PTF0", "type": "external" } ], "mass": 54245.0, "length": 480, "protein_name": "Probable ATP-dependent RNA helicase DDX49", "gene_name": "Ddx49", "organism": "Rat", "refseq_name": "probable ATP-dependent RNA helicase DDX49 isoform 1", "refseq_ac": [ { "id": "NP_001108495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108495", "type": "external" } ], "gene_names_uniprotkb": "Ddx49", "gene_names_refseq": "Ddx49", "protein_names_uniprotkb": "Probable ATP-dependent RNA helicase DDX49; 3.6.4.13; DEAD box protein 49", "protein_names_refseq": "DEAD (Asp-Glu-Ala-Asp) box polypeptide 49; probable ATP-dependent RNA helicase DDX49 isoform 1; probable ATP-dependent RNA helicase DDX49", "tax_id": 10116, "disease": "", "pathway": " (rno:290660); (R-RNO-6791226)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "ATP-dependent RNA helicase that plays a role in various aspects of RNA metabolism including the regulation of mRNA export and the levels of pre-ribosomal RNA. 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(Disease Ontology:DOID:10283); intestinal atresia (Disease Ontology:DOID:10486); stomach cancer (Disease Ontology:DOID:10534); retinitis pigmentosa (Disease Ontology:DOID:10584); portal hypertension (Disease Ontology:DOID:10762); essential hypertension (Disease Ontology:DOID:10825); hypospadias (Disease Ontology:DOID:10892); urinary bladder cancer (Disease Ontology:DOID:11054); acrocephalosyndactylia (Disease Ontology:DOID:12960); primary pulmonary hypertension (Disease Ontology:DOID:14557); Pfeiffer syndrome (Disease Ontology:DOID:14705); Saethre-Chotzen syndrome (Disease Ontology:DOID:14768); breast cancer (Disease Ontology:DOID:1612); squamous cell carcinoma (Disease Ontology:DOID:1749); transient cerebral ischemia (Disease Ontology:DOID:224); Crouzon syndrome (Disease Ontology:DOID:2339); craniosynostosis (Disease Ontology:DOID:2340); transitional cell carcinoma (Disease Ontology:DOID:2671); endometriosis (Disease Ontology:DOID:289); high grade glioma (Disease Ontology:DOID:3070); dysgerminoma (Disease Ontology:DOID:4441); stomach carcinoma (Disease Ontology:DOID:5517); hepatocellular carcinoma (Disease Ontology:DOID:684); female breast carcinoma (Disease Ontology:DOID:7843); intestinal volvulus (Disease Ontology:DOID:8445); Kaposi's sarcoma (Disease Ontology:DOID:8632)", "pathway": " (rno:25022); (R-RNO-109704); (R-RNO-1257604); (R-RNO-190375); (R-RNO-190377); (R-RNO-5654221); (R-RNO-5654695); (R-RNO-5654699); (R-RNO-5654700); (R-RNO-5654727); (R-RNO-5673001); (R-RNO-6811558)", "pathway_count": 12, "publication_count": 2, "publication_id_list": "32626929;35599572", "class_list": "", "function": "Knockdown of lncRNA TUG1 alleviates diabetic retinal vascular dysfunction through regulating miR-524-5p/FGFR2., [RefSeq, PubMed]; MiR2175p regulates myogenesis in skeletal muscle stem cells by targeting FGFR2., [RefSeq, PubMed]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, 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"protein_name": "Large ribosomal subunit protein uL23", "gene_name": "Rpl23al1", "organism": "Rat", "refseq_name": "large ribosomal subunit protein uL23-like", "refseq_ac": [ { "id": "XP_038959426", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038959426", "type": "external" } ], "gene_names_uniprotkb": "Rpl23al1; RGD1564606", "gene_names_refseq": "Rpl23al1", "protein_names_uniprotkb": "Large ribosomal subunit protein uL23; 60S ribosomal protein L23a", "protein_names_refseq": "large ribosomal subunit protein uL23-like", "tax_id": 10116, "disease": "", "pathway": " (rno:499523)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA. May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019843 rRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005634 nucleus;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LT35-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LTE0-1", "uniprot_id": [ { "id": "TANC2_RAT", "url": "https://www.uniprot.org/uniprot/F1LTE0", "type": "external" } ], "mass": 219812.0, "length": 1992, "protein_name": "Protein TANC2", "gene_name": "Tanc2", "organism": "Rat", "refseq_name": "protein TANC2 isoform 2", "refseq_ac": [ { "id": "NP_001178582", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178582", "type": "external" } ], "gene_names_uniprotkb": "Tanc2", "gene_names_refseq": "RGD1309285; Tanc2", "protein_names_uniprotkb": "Protein TANC2", "protein_names_refseq": "protein TANC2 isoform 2; protein TANC2", "tax_id": 10116, "disease": "intellectual developmental disorder with autistic features and language delay, with or without seizures (Disease Ontology:DOID:0081430)", "pathway": " (rno:303599)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "22673903;30021165;38843836", "class_list": "", "function": "Liprin-alpha and TANC2 are not part of the KIF1A-cargo complex but capture dense core vesicles at dendritic spines., [RefSeq, PubMed]; Scaffolding protein in the dendritic spines which acts as immobile postsynaptic posts able to recruit KIF1A-driven dense core vesicles to dendritic spines., [UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0098919 structural constituent of postsynaptic density", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0014069 postsynaptic density;GO:0030424 axon;GO:0043197 dendritic spine;GO:0099092 postsynaptic density, intracellular component", "go_biological_process": "GO:0001701 in utero embryonic development;GO:0060998 regulation of dendritic spine development;GO:0061001 regulation of dendritic spine morphogenesis;GO:0099519 dense core granule cytoskeletal transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F1LTE0-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0100000011001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LTF8-1", "uniprot_id": [ { "id": "F1LTF8_RAT", "url": "https://www.uniprot.org/uniprot/F1LTF8", "type": "external" } ], "mass": 201525.0, "length": 1817, "protein_name": "Laminin subunit alpha-4", "gene_name": "Lama4", "organism": "Rat", "refseq_name": "laminin subunit alpha-4 precursor", "refseq_ac": [ { "id": "NP_001296376", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001296376", "type": "external" } ], "gene_names_uniprotkb": "Lama4", "gene_names_refseq": "Lama4; RGD1560062", "protein_names_uniprotkb": "Laminin subunit alpha-4; Laminin-14 subunit alpha; Laminin-8 subunit alpha; Laminin-9 subunit alpha", "protein_names_refseq": "laminin subunit alpha-4 precursor; laminin, alpha 4", "tax_id": 10116, "disease": "dilated cardiomyopathy 1JJ (Disease Ontology:DOID:0110438)", "pathway": " (rno:309816); (R-RNO-3000157); (R-RNO-8874081); (R-RNO-9913351)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "12787401;22673903", "class_list": "", "function": "Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components., [UniProtKB, UniProtKB]; Synthesized by mesangial cells (MC) and persists in the mature glomerulus; suggested that laminin alpha4 plays an important role in MC differentiation and in the maintenance of MC phenotype., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031594 neuromuscular junction;GO:0045202 synapse;GO:0043083 synaptic cleft;GO:0005604 basement membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0007165 signal transduction;GO:0007399 nervous system development;GO:0030155 regulation of cell adhesion;GO:0050873 brown fat cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1LTF8-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LTK0-1", "uniprot_id": [ { "id": "F1LTK0_RAT", "url": "https://www.uniprot.org/uniprot/F1LTK0", "type": "external" } ], "mass": 94234.0, "length": 866, "protein_name": "Similar to human chromosome 2 open reading frame 78", "gene_name": "C1h2orf78", "organism": "Rat", "refseq_name": "uncharacterized protein C2orf78 homolog isoform X1", "refseq_ac": [ { "id": "XP_001073960", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001073960", "type": "external" } ], "gene_names_uniprotkb": "C1h2orf78; LOC690284", "gene_names_refseq": "C1h2orf78", "protein_names_uniprotkb": "Similar to human chromosome 2 open reading frame 78", "protein_names_refseq": "uncharacterized protein C2orf78 homolog isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:690284)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LTK0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LUS2-1", "uniprot_id": [ { "id": "F1LUS2_RAT", "url": "https://www.uniprot.org/uniprot/F1LUS2", "type": "external" } ], "mass": 98099.0, "length": 867, "protein_name": "Protein argonaute-3", "gene_name": "Ago3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ago3; AGO3; EIF2C3", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein argonaute-3; Argonaute3; Eukaryotic translation initiation factor 2C 3; eIF-2C 3; eIF2C 3", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:313593); (R-RNO-203927); (R-RNO-426486); (R-RNO-426496)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0046872 metal ion binding;GO:0003725 double-stranded RNA binding;GO:0003727 single-stranded RNA binding;GO:0035198 miRNA binding", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000932 P-body;GO:0036464 cytoplasmic ribonucleoprotein granule", "go_biological_process": "GO:0070922 RISC complex assembly;GO:0010628 positive regulation of gene expression;GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction;GO:0006402 mRNA catabolic process;GO:0031054 pre-miRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LUS2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LUV3-1", "uniprot_id": [ { "id": "F1LUV3_RAT", "url": "https://www.uniprot.org/uniprot/F1LUV3", "type": "external" } ], "mass": 43625.0, "length": 398, "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "ENSRNOG00000066746", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ENSRNOG00000066746", "gene_names_refseq": "", "protein_names_uniprotkb": "Glyceraldehyde-3-phosphate dehydrogenase; 1.2.1.12", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.2.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.12", "type": "external" }, { "id": "2.6.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.99.-", "type": "external" } ], "go_molecular_function": "GO:0051287 NAD binding;GO:0016740 transferase activity;GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0006417 regulation of translation;GO:0045087 innate immune response;GO:0006915 apoptotic process;GO:0006094 gluconeogenesis;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LUV3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LUZ0-1", "uniprot_id": [ { "id": "F1LUZ0_RAT", "url": "https://www.uniprot.org/uniprot/F1LUZ0", "type": "external" } ], "mass": 61723.0, "length": 533, "protein_name": "Zinc finger protein 791", "gene_name": "Zfp791", "organism": "Rat", "refseq_name": "zinc finger protein 791-like", "refseq_ac": [ { "id": "XP_008770655", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008770655", "type": "external" } ], "gene_names_uniprotkb": "Zfp791", "gene_names_refseq": "Zfp791", "protein_names_uniprotkb": "Zinc finger protein 791", "protein_names_refseq": "zinc finger protein 791-like", "tax_id": 10116, "disease": "", "pathway": " (rno:100363196)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LUZ0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LV47-1", "uniprot_id": [ { "id": "F1LV47_RAT", "url": "https://www.uniprot.org/uniprot/F1LV47", "type": "external" } ], "mass": 37028.0, "length": 344, "protein_name": "Olfactory receptor", "gene_name": "Or10ah1-ps1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Or10ah1-ps1", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, 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"Dclk3 is expressed in the pineal gland at levels >16-fold greater than the median expression level in other tissues; in addition, expression exhibits a >10-fold increase at night., [RefSeq, PubMed]; This gene encodes a member of the protein kinase superfamily and the doublecortin family. Differently from the other two closely related family members (DCLK1 and DCLK2), the protein encoded by this gene contains only one N-terminal doublecortin domain and is unable to bind microtubules and to regulate microtubule polymerization. The protein contains a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmoduline-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. [provided by RefSeq, Sep 2010]., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.4.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.18", "type": "external" }, { "id": "3.1.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.24.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:1900181 negative regulation of protein localization to nucleus;GO:0018105 peptidyl-serine phosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LWF2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LWI7-1", "uniprot_id": [ { "id": "F1LWI7_RAT", "url": "https://www.uniprot.org/uniprot/F1LWI7", "type": "external" } ], "mass": 62590.0, "length": 584, "protein_name": "EZH inhibitory protein", "gene_name": "Ezhip", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ezhip", "gene_names_refseq": "", "protein_names_uniprotkb": "EZH inhibitory protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-212300)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0180000 histone methyltransferase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006325 chromatin organization;GO:0040029 epigenetic regulation of gene expression;GO:0048599 oocyte development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LWI7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LWZ0-1", "uniprot_id": [ { "id": "F1LWZ0_RAT", "url": "https://www.uniprot.org/uniprot/F1LWZ0", "type": "external" } ], "mass": 34582.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or51g2", "organism": "Rat", "refseq_name": "olfactory receptor Olr69", "refseq_ac": [ { "id": "NP_001001280", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001280", "type": "external" } ], "gene_names_uniprotkb": "Or51g2", "gene_names_refseq": "Olr69; Or51g2", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 69; olfactory receptor Olr69; olfactory receptor gene Olr69", "tax_id": 10116, "disease": "", "pathway": " (rno:365326)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0071396 cellular response to lipid", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LWZ0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LX23-1", "uniprot_id": [ { "id": "F1LX23_RAT", "url": "https://www.uniprot.org/uniprot/F1LX23", "type": "external" } ], "mass": 73761.0, "length": 642, "protein_name": "Zinc finger protein 267", "gene_name": "Zfp267", "organism": "Rat", "refseq_name": "uncharacterized protein LOC100359945 isoform 2", "refseq_ac": [ { "id": "NP_001395763", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001395763", "type": "external" } ], "gene_names_uniprotkb": "Zfp267; LOC100359945; Rslcan18", "gene_names_refseq": "Rslcan18; Zfp267", "protein_names_uniprotkb": "Zinc finger protein 267", "protein_names_refseq": "rCG41562-like; regulator of sex-limitation candidate 18; uncharacterized protein LOC100359945 isoform 2; zinc finger protein 345; zinc finger protein 883", "tax_id": 10116, "disease": "", "pathway": " (rno:100359945)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LX23-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LX28-1", "uniprot_id": [ { "id": "F1LX28_RAT", "url": "https://www.uniprot.org/uniprot/F1LX28", "type": "external" } ], "mass": 67130.0, "length": 594, "protein_name": "Acyl-coenzyme A thioesterase 11", "gene_name": "Acot11", "organism": "Rat", "refseq_name": "acyl-coenzyme A thioesterase 11", "refseq_ac": [ { "id": "NP_001258312", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258312", "type": "external" } ], "gene_names_uniprotkb": "Acot11", "gene_names_refseq": "Acot11; Thea", "protein_names_uniprotkb": "Acyl-coenzyme A thioesterase 11; 3.1.2.2; Acyl-CoA thioester hydrolase 11; Adipose-associated thioesterase; Brown fat-inducible thioesterase; Palmitoyl-coenzyme A thioesterase", "protein_names_refseq": "acyl-coenzyme A thioesterase 11; thioesterase, adipose associated", "tax_id": 10116, "disease": "", "pathway": " (rno:100363074); (R-RNO-77289)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.5.2.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.2.6", "type": "external" }, { "id": "3.1.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.-", "type": "external" }, { "id": "3.1.2.14", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.14", "type": "external" }, { "id": "3.1.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.1", "type": "external" }, { "id": "2.3.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.16", "type": "external" }, { "id": "2.3.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.9", "type": "external" }, { "id": "3.1.2.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.22", "type": "external" }, { "id": "3.1.1.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4", "type": "external" }, { "id": "3.1.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.5", "type": "external" }, { "id": "3.1.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.27", "type": "external" }, { "id": "2.3.1.65", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.65", "type": "external" }, { "id": "3.1.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.11", "type": "external" }, { "id": "3.1.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.3", "type": "external" }, { "id": "3.1.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.5", "type": "external" } ], "go_molecular_function": "GO:0047617 fatty acyl-CoA hydrolase activity;GO:0052689 carboxylic ester hydrolase activity;GO:0008289 lipid binding;GO:0052816 long-chain fatty acyl-CoA hydrolase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005759 mitochondrial matrix;GO:0005829 cytosol", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0006637 acyl-CoA metabolic process;GO:0009409 response to cold;GO:0009266 response to temperature stimulus;GO:0120163 negative regulation of cold-induced thermogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LX28-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LX58-1", "uniprot_id": [ { "id": "F1LX58_RAT", "url": "https://www.uniprot.org/uniprot/F1LX58", "type": "external" } ], "mass": 69389.0, "length": 625, "protein_name": "Fc receptor-like 5", "gene_name": "Fcrl5", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Fcrl5; Fcrl3", "gene_names_refseq": "", "protein_names_uniprotkb": "Fc receptor-like 5", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015026 coreceptor activity;GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0043235 receptor complex;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0051280 negative regulation of release of sequestered calcium ion into cytosol;GO:0042113 B cell activation;GO:0050859 negative regulation of B cell receptor signaling pathway;GO:0006955 immune response;GO:0007166 cell surface receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LX58-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LX87-1", "uniprot_id": [ { "id": "F1LX87_RAT", "url": "https://www.uniprot.org/uniprot/F1LX87", "type": "external" } ], "mass": 133040.0, "length": 1204, "protein_name": "Ankyrin repeat domain 31", "gene_name": "Ankrd31", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ankrd31", "gene_names_refseq": "", "protein_names_uniprotkb": "Ankyrin repeat domain 31", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000785 chromatin", "go_biological_process": "GO:0007129 homologous chromosome pairing at meiosis;GO:0010780 meiotic DNA double-strand break formation involved in reciprocal meiotic recombination;GO:1903343 positive regulation of meiotic DNA double-strand break formation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LX87-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LXD9-1", "uniprot_id": [ { "id": "F1LXD9_RAT", "url": "https://www.uniprot.org/uniprot/F1LXD9", "type": "external" } ], "mass": 197065.0, "length": 1670, "protein_name": "Coiled-coil domain containing 180", "gene_name": "Ccdc180", "organism": "Rat", "refseq_name": "coiled-coil domain-containing protein 180", "refseq_ac": [ { "id": "NP_001414613", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414613", "type": "external" } ], "gene_names_uniprotkb": "Ccdc180; LOC100910460", "gene_names_refseq": "Ccdc180", "protein_names_uniprotkb": "Coiled-coil domain containing 180", "protein_names_refseq": "coiled-coil domain-containing protein 180", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LXD9-1", "record_type": "protein", "filter_code": "0000000.0000000.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LXE2-1", "uniprot_id": [ { "id": "F1LXE2_RAT", "url": "https://www.uniprot.org/uniprot/F1LXE2", "type": "external" } ], "mass": 35281.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or51a7", "organism": "Rat", "refseq_name": "olfactory receptor Olr67", "refseq_ac": [ { "id": "NP_001001279", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001279", "type": "external" } ], "gene_names_uniprotkb": "Or51a7; Or51a7b", "gene_names_refseq": "Olr67; Or51a7a; Or51a7b; Or51a7", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 67; olfactory receptor Olr67; olfactory receptor family 51 subfamily A member 7A; olfactory receptor family 51 subfamily A member 7B; olfactory receptor gene Olr67", "tax_id": 10116, "disease": "", "pathway": " (rno:365324)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0071396 cellular response to lipid", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LXE2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LXT3-1", "uniprot_id": [ { "id": "F1LXT3_RAT", "url": "https://www.uniprot.org/uniprot/F1LXT3", "type": "external" } ], "mass": 317857.0, "length": 2795, "protein_name": "UTP20 small subunit processome component", "gene_name": "Utp20", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Utp20", "gene_names_refseq": "", "protein_names_uniprotkb": "UTP20 small subunit processome component", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:314713); (R-RNO-6791226)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "16641100;29393594", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005730 nucleolus;GO:0030686 90S preribosome;GO:0032040 small-subunit processome", "go_biological_process": "GO:0006364 rRNA processing;GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1LXT3-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LY69-1", "uniprot_id": [ { "id": "F1LY69_RAT", "url": "https://www.uniprot.org/uniprot/F1LY69", "type": "external" } ], "mass": 165880.0, "length": 1463, "protein_name": "Intraflagellar transport protein 140 homolog", "gene_name": "Ift140", "organism": "Rat", "refseq_name": "intraflagellar transport protein 140 homolog", "refseq_ac": [ { "id": "NP_001414055", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414055", "type": "external" } ], "gene_names_uniprotkb": "Ift140", "gene_names_refseq": "Ift140", "protein_names_uniprotkb": "Intraflagellar transport protein 140 homolog; WD and tetratricopeptide repeats protein 2", "protein_names_refseq": "intraflagellar transport protein 140 homolog", "tax_id": 10116, "disease": "retinitis pigmentosa 80 (Disease Ontology:DOID:0061111); asphyxiating thoracic dystrophy 1 (Disease Ontology:DOID:0110085); short-rib thoracic dysplasia 9 with or without polydactyly (Disease Ontology:DOID:0110097)", "pathway": " (rno:100362124); (R-RNO-5610787); (R-RNO-5620924)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs). 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10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005245 voltage-gated calcium channel activity", "go_cellular_component": "GO:0036128 CatSper complex;GO:0005783 endoplasmic reticulum;GO:0001669 acrosomal vesicle;GO:0097228 sperm principal piece;GO:0097225 sperm midpiece", "go_biological_process": "GO:0030317 flagellated sperm motility;GO:0048240 sperm capacitation;GO:0006814 sodium ion transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LZS9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LZW6-1", "uniprot_id": [ { "id": "S2513_RAT", "url": "https://www.uniprot.org/uniprot/F1LZW6", "type": "external" } ], "mass": 74399.0, "length": 676, "protein_name": "Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial", "gene_name": "Slc25a13", "organism": "Rat", "refseq_name": "electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial isoform 1", "refseq_ac": [ { "id": "NP_001406553", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001406553", "type": "external" } ], "gene_names_uniprotkb": "Slc25a13; Agc2", "gene_names_refseq": "RGD1565889; Slc25a13", "protein_names_uniprotkb": "Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial; Solute carrier family 25 member 13", "protein_names_refseq": "calcium-binding mitochondrial carrier protein Aralar2; electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial isoform 1; electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial; solute carrier family 25 (aspartate/glutamate carrier), member 13; solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13; solute carrier family 25, member 13 (citrin)", "tax_id": 10116, "disease": "neonatal-onset type II citrullinemia (Disease Ontology:DOID:0070341); adult-onset type II citrullinemia (Disease Ontology:DOID:0070342); intrahepatic cholestasis (Disease Ontology:DOID:1852); common bile duct disease (Disease Ontology:DOID:4137); citrullinemia (Disease Ontology:DOID:9273)", "pathway": " (rno:362322); (R-RNO-8963693); (R-RNO-9856872)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "34502162;4436323;486467", "class_list": "", "function": "Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle (PubMed:4436323). Substrate exchange across the membrane occurs consecutively with one substrate being transported first, then dissociating from the substrate binding site before the second substrate binds for transport in the opposite direction (By similarity). Also mediates the uptake of L-cysteinesulfinate (3-sulfino-L-alanine) by mitochondria in exchange for L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation (PubMed:486467). Lacks transport activity towards gamma-aminobutyric acid (GABA) (By similarity)., [UniProtKB, PubMed, PubMed, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0005509 calcium ion binding;GO:0005313 L-glutamate transmembrane transporter activity;GO:0015172 acidic amino acid transmembrane transporter activity;GO:0015183 L-aspartate transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0051592 response to calcium ion;GO:0006754 ATP biosynthetic process;GO:0006094 gluconeogenesis;GO:0045333 cellular respiration;GO:0015810 aspartate transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F1LZW6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0100000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M067-1", "uniprot_id": [ { "id": "F1M067_RAT", "url": "https://www.uniprot.org/uniprot/F1M067", "type": "external" } ], "mass": 64484.0, "length": 593, "protein_name": "Sodium-independent sulfate anion transporter", "gene_name": "Slc26a11", "organism": "Rat", "refseq_name": "sodium-independent sulfate anion transporter", "refseq_ac": [ { "id": "NP_001385736", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385736", "type": "external" } ], "gene_names_uniprotkb": "Slc26a11", "gene_names_refseq": "Slc26a11", "protein_names_uniprotkb": "Sodium-independent sulfate anion transporter; Solute carrier family 26 member 11", "protein_names_refseq": "sodium-independent sulfate anion transporter; solute carrier family 26 (anion exchanger), member 11", "tax_id": 10116, "disease": "", "pathway": " (rno:360670); (R-RNO-174362); (R-RNO-427601)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "25910210;37380823", "class_list": "", "function": "Results demonstrate that prolonged Na+ entry via either of two independent pathways (either VGSCs or NMDARs) converge to activate a Cl- influx pathway via SLC26A11 that is ultimately required for neuronal swelling and subsequent cell death., [RefSeq, PubMed]; SLC26A11 Inhibition Reduces Oncotic Neuronal Death and Attenuates Stroke Reperfusion Injury., [RefSeq, PubMed]; Sodium-independent anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport. Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC). In the kidney, mediates chloride-bicarbonate exchange, facilitating V-ATPase-mediated acid secretion. May function as a chloride channel, playing an important role in moderating chloride homeostasis and neuronal activity in the cerebellum., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008509 monoatomic anion transmembrane transporter activity;GO:0005254 chloride channel activity;GO:0008271 secondary active sulfate transmembrane transporter activity;GO:0015116 sulfate transmembrane transporter activity;GO:0140900 chloride:bicarbonate antiporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:1902476 chloride transmembrane transport;GO:1902358 sulfate transmembrane transport;GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1M067-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M076-1", "uniprot_id": [ { "id": "F1M076_RAT", "url": "https://www.uniprot.org/uniprot/F1M076", "type": "external" } ], "mass": 80517.0, "length": 699, "protein_name": "Zinc finger protein 770", "gene_name": "Zfp770", "organism": "Rat", "refseq_name": "zinc finger protein 770", "refseq_ac": [ { "id": "NP_001386575", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386575", "type": "external" } ], "gene_names_uniprotkb": "Zfp770; LOC100366023; Znf770", "gene_names_refseq": "Zfp770; Znf770", "protein_names_uniprotkb": "Zinc finger protein 770", "protein_names_refseq": "Zinc finger protein 770-like; zinc finger protein 770", "tax_id": 10116, "disease": "", "pathway": " (rno:691610); (R-RNO-212436)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M076-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M0A0-1", "uniprot_id": [ { "id": "F1M0A0_RAT", "url": "https://www.uniprot.org/uniprot/F1M0A0", "type": "external" } ], "mass": 114679.0, "length": 981, "protein_name": "Anoctamin", "gene_name": "Ano3", "organism": "Rat", "refseq_name": "anoctamin-3", "refseq_ac": [ { "id": "NP_001417331", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417331", "type": "external" } ], "gene_names_uniprotkb": "Ano3", "gene_names_refseq": "Ano3; Tmem16c", "protein_names_uniprotkb": "Anoctamin", "protein_names_refseq": "anoctamin-3; transmembrane protein 16C", "tax_id": 10116, "disease": "dystonia 24 (Disease Ontology:DOID:0090052)", "pathway": " (R-RNO-2672351)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23872594;33972431", "class_list": "", "function": "TMEM16C is involved in thermoregulation and protects rodent pups from febrile seizures., [RefSeq, PubMed]; This study thus reveals that TMEM16C enhances K(Na) channel activity in DRG neurons and regulates the processing of pain messages., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0017128 phospholipid scramblase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005929 cilium", "go_biological_process": "GO:0045332 phospholipid translocation;GO:0061590 calcium activated phosphatidylcholine scrambling;GO:0061591 calcium activated galactosylceramide scrambling;GO:0016048 detection of temperature stimulus;GO:0050982 detection of mechanical stimulus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1M0A0-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M0C4-1", "uniprot_id": [ { "id": "F1M0C4_RAT", "url": "https://www.uniprot.org/uniprot/F1M0C4", "type": "external" } ], "mass": 33010.0, "length": 287, "protein_name": "Potassium channel tetramerization domain containing 14", "gene_name": "Kctd14", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Kctd14", "gene_names_refseq": "", "protein_names_uniprotkb": "Potassium channel tetramerization domain containing 14", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:308836)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0051260 protein homooligomerization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M0C4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M0L3-1", "uniprot_id": [ { "id": "F1M0L3_RAT", "url": "https://www.uniprot.org/uniprot/F1M0L3", "type": "external" } ], "mass": 431780.0, "length": 3986, "protein_name": "Histone-lysine N-methyltransferase", "gene_name": "Kmt2a", "organism": "Rat", "refseq_name": "histone-lysine N-methyltransferase 2A isoform X1", "refseq_ac": [ { "id": "XP_038938273", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038938273", "type": "external" } ], "gene_names_uniprotkb": "Kmt2a; Mll1; Mll", "gene_names_refseq": "Kmt2a; Mll1; Mll", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase; 2.1.1.364", "protein_names_refseq": "histone-lysine N-methyltransferase 2A isoform X1", "tax_id": 10116, "disease": "non-Hodgkin lymphoma (Disease Ontology:DOID:0060060); prostate cancer (Disease Ontology:DOID:10283); congenital heart disease (Disease Ontology:DOID:1682); transient cerebral ischemia (Disease Ontology:DOID:224); cervical cancer (Disease Ontology:DOID:4362); myelofibrosis (Disease Ontology:DOID:4971); acute myeloid leukemia (Disease Ontology:DOID:9119); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (R-RNO-3214841); (R-RNO-8936459); (R-RNO-8939236); (R-RNO-9772755); (R-RNO-9909649)", "pathway_count": 5, "publication_count": 1, 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May convert inactive angiotensin I into the biologically active angiotensin II. 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"reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0042277 peptide binding", "go_cellular_component": "GO:0042629 mast cell granule", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PTQ9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LNR1-1", "uniprot_id": [ { "id": "F1LNR1_RAT", "url": "https://www.uniprot.org/uniprot/F1LNR1", "type": "external" } ], "mass": 163908.0, "length": 1488, "protein_name": "Cytoplasmic linker associated protein 1", "gene_name": "Clasp1", "organism": "Rat", "refseq_name": "CLIP-associating protein 1 isoform X21", "refseq_ac": [ { "id": "XP_063128328", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063128328", "type": "external" } ], "gene_names_uniprotkb": "Clasp1", "gene_names_refseq": "Clasp1", "protein_names_uniprotkb": "Cytoplasmic linker associated protein 1", "protein_names_refseq": "CLIP-associating protein 1 isoform X21", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-141430); (R-RNO-141444); (R-RNO-2467813); (R-RNO-2500257); (R-RNO-2565942); (R-RNO-380259); (R-RNO-380270); (R-RNO-380284); (R-RNO-380320); (R-RNO-5620912); (R-RNO-5663220); (R-RNO-68877); (R-RNO-8854518); (R-RNO-9648025)", "pathway_count": 14, "publication_count": 2, "publication_id_list": "22673903;38843836", "class_list": "", "function": "Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0002162 dystroglycan binding;GO:0051010 microtubule plus-end binding;GO:0043515 kinetochore binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005813 centrosome;GO:0005819 spindle;GO:0005874 microtubule;GO:0000776 kinetochore", "go_biological_process": "GO:0031110 regulation of microtubule polymerization or depolymerization;GO:0051494 negative regulation of cytoskeleton organization;GO:1902904 negative regulation of supramolecular fiber organization;GO:0051301 cell division;GO:0007026 negative regulation of microtubule depolymerization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F1LNR1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZXT2-1", "uniprot_id": [ { "id": "D3ZXT2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZXT2", "type": "external" } ], "mass": 141307.0, "length": 1231, "protein_name": "Cohesin subunit SA", "gene_name": "Stag2", "organism": "Rat", "refseq_name": "cohesin subunit SA-2 isoform 1", "refseq_ac": [ { "id": "NP_001166978", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001166978", "type": "external" } ], "gene_names_uniprotkb": "Stag2", "gene_names_refseq": "RGD1562042; Stag2", "protein_names_uniprotkb": "Cohesin subunit SA; SCC3 homolog; Stromal antigen", "protein_names_refseq": "cohesin subunit SA-2 isoform 1; cohesin subunit SA-2; stromal antigen 2", "tax_id": 10116, "disease": "Holoprosencephaly 13, X-linked (Disease Ontology:DOID:0060954); Mullegama-Klein-Martinez syndrome (Disease Ontology:DOID:0111845)", "pathway": " (rno:313304); (R-RNO-2467813); (R-RNO-2468052); (R-RNO-2470946); (R-RNO-2500257); (R-RNO-3108214)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0001650 fibrillar center;GO:0000775 chromosome, centromeric region;GO:0016363 nuclear matrix;GO:0000785 chromatin", "go_biological_process": "GO:0051301 cell division;GO:0090307 mitotic spindle assembly;GO:0007062 sister chromatid cohesion;GO:0019827 stem cell population maintenance", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZXT2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1MAP4-1", "uniprot_id": [ { "id": "F1MAP4_RAT", "url": "https://www.uniprot.org/uniprot/F1MAP4", "type": "external" } ], "mass": 122806.0, "length": 1145, "protein_name": "Multiple epidermal growth factor-like domains protein 10", "gene_name": "Megf10", "organism": "Rat", "refseq_name": "multiple epidermal growth factor-like domains protein 10 precursor", "refseq_ac": [ { "id": "NP_001094127", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094127", "type": "external" } ], "gene_names_uniprotkb": "Megf10", "gene_names_refseq": "Megf10", "protein_names_uniprotkb": "Multiple epidermal growth factor-like domains protein 10", "protein_names_refseq": "multiple epidermal growth factor-like domains protein 10 precursor; multiple epidermal growth factor-like domains protein 10", "tax_id": 10116, "disease": "congenital myopathy 10B (Disease Ontology:DOID:0081345); congenital myopathy 10A (Disease Ontology:DOID:0111333); neurodegenerative disease (Disease Ontology:DOID:1289); myopathy (Disease Ontology:DOID:423)", "pathway": " (rno:291445)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005044 scavenger receptor activity;GO:0005112 Notch binding;GO:0001849 complement component C1q complex binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0001891 phagocytic cup", "go_biological_process": "GO:0022409 positive regulation of cell-cell adhesion;GO:0014816 skeletal muscle satellite cell differentiation;GO:0034109 homotypic cell-cell adhesion;GO:0042552 myelination;GO:0043652 engulfment of apoptotic cell", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1MAP4-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0RAI4-1", "uniprot_id": [ { "id": "M0RAI4_RAT", "url": "https://www.uniprot.org/uniprot/M0RAI4", "type": "external" } ], "mass": 123871.0, "length": 1115, "protein_name": "Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial", "gene_name": "Ears2; Gga2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Ears2; Gga2; Gga2", "gene_names_refseq": "", "protein_names_uniprotkb": "Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial; 6.1.1.17; 6.1.1.24; Glutamate--tRNA(Gln) ligase EARS2, mitochondrial; Glutamyl-tRNA synthetase; Mitochondrial glutamyl-tRNA synthetase", "protein_names_refseq": "", "tax_id": 10116, "disease": "combined oxidative phosphorylation deficiency 12 (Disease Ontology:DOID:0111493); neurodegenerative disease (Disease Ontology:DOID:1289); lysosomal storage disease (Disease Ontology:DOID:3211)", "pathway": " (rno:293455); (rno:361641)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Non-discriminating glutamyl-tRNA synthetase that catalyzes aminoacylation of both mitochondrial tRNA(Glu) and tRNA(Gln) and participates in RNA aminoacylation for mitochondrial protein translation. Attachs glutamate to tRNA(Glu) or tRNA(Gln) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) or tRNA(Gln). In vitro, cytoplasmic tRNA(Gln) is slightly glutamylated, but with low activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.1.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.17", "type": "external" }, { "id": "6.1.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.24", "type": "external" }, { "id": "6.1.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.15", "type": "external" } ], "go_molecular_function": "GO:0031267 small GTPase binding;GO:0035091 phosphatidylinositol binding;GO:0043130 ubiquitin binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0031901 early endosome membrane;GO:0030136 clathrin-coated vesicle;GO:0005802 trans-Golgi network;GO:0005739 mitochondrion", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0043001 Golgi to plasma membrane protein transport;GO:0034394 protein localization to cell surface;GO:0016192 vesicle-mediated transport;GO:0006424 glutamyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0RAI4-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1MAF1-1", "uniprot_id": [ { "id": "F1MAF1_RAT", "url": "https://www.uniprot.org/uniprot/F1MAF1", "type": "external" } ], "mass": 57109.0, "length": 525, "protein_name": "Heat shock transcription factor 1", "gene_name": "Hsf1", "organism": "Rat", "refseq_name": "heat shock factor protein 1", "refseq_ac": [ { "id": "NP_077369", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_077369", "type": "external" } ], "gene_names_uniprotkb": "Hsf1", "gene_names_refseq": "Hsf1", "protein_names_uniprotkb": "Heat shock transcription factor 1", "protein_names_refseq": "heat shock factor protein 1", "tax_id": 10116, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); cryptorchidism (Disease Ontology:DOID:11383); Huntington's disease (Disease Ontology:DOID:12858); neurodegenerative disease (Disease Ontology:DOID:1289); Parkinson's disease (Disease Ontology:DOID:14330); transient cerebral ischemia (Disease Ontology:DOID:224); congestive heart failure (Disease Ontology:DOID:6000); muscular atrophy (Disease Ontology:DOID:767)", "pathway": " (rno:79245); (R-RNO-3371453); (R-RNO-3371511); (R-RNO-3371568); (R-RNO-3371571); (R-RNO-9841251)", "pathway_count": 6, "publication_count": 6, "publication_id_list": "22673903;31522994;32457290;33989081;34530848;36741074", "class_list": "", "function": "BAG3 expression and sarcomere localization in the human heart are linked to HSF-1 and are differentially affected by sex and disease., [RefSeq, PubMed]; Decreased expression of FBXW7 by ERK1/2 activation in drug-resistant cancer cells confers transcriptional activation of MDR1 by suppression of ubiquitin degradation of HSF1. Publication Status: Online-Only, [RefSeq, PubMed]; HSF1 Alleviates Brain Injury by Inhibiting NLRP3-Induced Pyroptosis in a Sepsis Model. Publication Status: Online-Only, [RefSeq, PubMed]; HSF1 is involved in suppressing A1 phenotype conversion of astrocytes following spinal cord injury in rats. Publication Status: Online-Only, [RefSeq, PubMed]; Localized to both the cytoplasm and nuclei of myometrial cells in both muscle layers throughout gestation, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0042802 identical protein binding;GO:0046982 protein heterodimerization activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0097165 nuclear stress granule;GO:0005813 centrosome;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0016605 PML body", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0010628 positive regulation of gene expression;GO:0045931 positive regulation of mitotic cell cycle;GO:1900034 regulation of cellular response to heat;GO:0000165 MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F1MAF1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M7U0-1", "uniprot_id": [ { "id": "F1M7U0_RAT", "url": "https://www.uniprot.org/uniprot/F1M7U0", "type": "external" } ], "mass": 59879.0, "length": 546, "protein_name": "BTB domain containing 6", "gene_name": "Btbd6", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Btbd6", "gene_names_refseq": "", "protein_names_uniprotkb": "BTB domain containing 6", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:690367); (R-RNO-8951664); (R-RNO-983168)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0022008 neurogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M7U0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JVF0-1", "uniprot_id": [ { "id": "A0A0G2JVF0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JVF0", "type": "external" } ], "mass": 107336.0, "length": 965, "protein_name": "Rho GTPase activating protein 4", "gene_name": "Arhgap4", "organism": "Rat", "refseq_name": "rho GTPase-activating protein 4", "refseq_ac": [ { "id": "NP_653341", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_653341", "type": "external" } ], "gene_names_uniprotkb": "Arhgap4", "gene_names_refseq": "Arhgap4", "protein_names_uniprotkb": "Rho GTPase activating protein 4", "protein_names_refseq": "rho GTPase-activating protein 4", "tax_id": 10116, "disease": "", "pathway": " (rno:246249); (R-RNO-8980692); (R-RNO-9013148); (R-RNO-9013149)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "12414125;17804252;22673903", "class_list": "", "function": "ARHGAP4 occured in the hippocampus, ventral region of the brainstem and striatum, and in cerebellar granule cells. Subcellularly, ARHGAP4 localized to the Golgi complex and could redistribute to the microtubules, for example during mitosis., [RefSeq, PubMed]; These observations suggest that ARHGAP4 can act as a potent inhibitor of cell and axon motility when it is localized to the leading edge of motile cells and axons., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005874 microtubule;GO:0030426 growth cone", "go_biological_process": "GO:0007165 signal transduction;GO:0010764 negative regulation of fibroblast migration;GO:0007399 nervous system development;GO:0030336 negative regulation of cell migration;GO:0035023 regulation of Rho protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2JVF0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A2H6-1", "uniprot_id": [ { "id": "D4A2H6_RAT", "url": "https://www.uniprot.org/uniprot/D4A2H6", "type": "external" } ], "mass": 40594.0, "length": 375, "protein_name": "RNA binding protein fox-1 homolog 3", "gene_name": "Rbfox3", "organism": "Rat", "refseq_name": "RNA binding protein fox-1 homolog 3 isoform 2", "refseq_ac": [ { "id": "NP_001127970", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001127970", "type": "external" } ], "gene_names_uniprotkb": "Rbfox3", "gene_names_refseq": "Hrnbp3; Neun; RGD1560070; Rbfox3", "protein_names_uniprotkb": "RNA binding protein fox-1 homolog 3", "protein_names_refseq": "RNA binding protein fox-1 homolog 3 isoform 2; RNA binding protein, fox-1 homolog 3; fox-1 homolog C; hexaribonucleotide binding protein 3; neuronal nuclei", "tax_id": 10116, "disease": "intellectual disability (Disease Ontology:DOID:1059); brain infarction (Disease Ontology:DOID:3454); middle cerebral artery infarction (Disease Ontology:DOID:3525)", "pathway": " (rno:287847)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "26987225;27487661;34146639", "class_list": "", "function": "EXPRESSION OF DOUBLECORTIN AND NeuN IN THE DEVELOPING CEREBELLAR NEURONS IN RAT, [RefSeq, PubMed]; Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD)., [UniProtKB, UniProtKB]; RNA-binding protein that regulates alternative splicing events., [UniProtKB, UniProtKB, UniProtKB]; Subcellular localization of neuronal nuclei (NeuN) antigen in size and calcitonin gene-related peptide (CGRP) populations of dorsal root ganglion (DRG) neurons during acute peripheral inflammation., [RefSeq, PubMed]; The presence of NeuN protein in the secretory epithelial cells of the exocrine part of this organ. The protein was located in the apical part of the cytoplasm slightly below the zone of zymogen granules., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003729 mRNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0043025 neuronal cell body;GO:0043204 perikaryon", "go_biological_process": "GO:0006397 mRNA processing;GO:0007399 nervous system development;GO:0008380 RNA splicing;GO:0000381 regulation of alternative mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D4A2H6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M943-1", "uniprot_id": [ { "id": "F1M943_RAT", "url": "https://www.uniprot.org/uniprot/F1M943", "type": "external" } ], "mass": 75433.0, "length": 673, "protein_name": "Armadillo repeat-containing protein 8", "gene_name": "Armc8", "organism": "Rat", "refseq_name": "armadillo repeat-containing protein 8", "refseq_ac": [ { "id": "NP_001166825", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001166825", "type": "external" } ], "gene_names_uniprotkb": "Armc8", "gene_names_refseq": "Armc8; RGD1310477", "protein_names_uniprotkb": "Armadillo repeat-containing protein 8", "protein_names_refseq": "armadillo repeat-containing protein 8", "tax_id": 10116, "disease": "", "pathway": " (rno:315949); (R-RNO-6798695); (R-RNO-9861718)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M943-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M853-1", "uniprot_id": [ { "id": "F1M853_RAT", "url": "https://www.uniprot.org/uniprot/F1M853", "type": "external" } ], "mass": 157504.0, "length": 1453, "protein_name": "Ribosome-binding protein 1", "gene_name": "Rrbp1", "organism": "Rat", "refseq_name": "ribosome-binding protein 1", "refseq_ac": [ { "id": "NP_001414528", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414528", "type": "external" } ], "gene_names_uniprotkb": "Rrbp1", "gene_names_refseq": "Rrbp1", "protein_names_uniprotkb": "Ribosome-binding protein 1; Ribosome receptor protein", "protein_names_refseq": "ribosome binding protein 1 homolog 180kDa (dog); ribosome-binding protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:311483)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "22673903;38815583;38843836", "class_list": "", "function": "Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane., [UniProtKB, UniProtKB, UniProtKB]; Axonal endoplasmic reticulum tubules control local translation via P180/RRBP1-mediated ribosome interactions., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0015031 protein transport;GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F1M853-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0Q5-1", "uniprot_id": [ { "id": "A0A0G2K0Q5_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0Q5", "type": "external" } ], "mass": 64045.0, "length": 589, "protein_name": "AT-rich interaction domain 5A", "gene_name": "Arid5a", "organism": "Rat", "refseq_name": "AT-rich interactive domain-containing protein 5A isoform X2", "refseq_ac": [ { "id": "XP_006244869", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006244869", "type": "external" } ], "gene_names_uniprotkb": "Arid5a", "gene_names_refseq": "Arid5a", "protein_names_uniprotkb": "AT-rich interaction domain 5A", "protein_names_refseq": "AT-rich interactive domain-containing protein 5A isoform X2", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0042802 identical protein binding;GO:0003714 transcription corepressor activity;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:1901985 positive regulation of protein acetylation;GO:0032740 positive regulation of interleukin-17 production;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K0Q5-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0RCW7-1", "uniprot_id": [ { "id": "M0RCW7_RAT", "url": "https://www.uniprot.org/uniprot/M0RCW7", "type": "external" } ], "mass": 28244.0, "length": 252, "protein_name": "Uncharacterized protein", "gene_name": "LOC134481322; Pilrb1l1; Pilrb1l3; Pilrb1l4; Pilrb2l3; Pilrb2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC134481322; Pilrb1l1; Pilrb1l3; Pilrb1l4; Pilrb2l3; Pilrb2; LOC102554231; LOC120095902; LOC134481169; LOC134481322; Pilrb1l3; Pilrb2l3; Pilrb2l5; RGD1561143; RGD1561730", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:102554231); (rno:304382); (rno:498169); (R-RNO-198933)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042288 MHC class I protein binding", "go_cellular_component": "GO:0016020 membrane;GO:0071944 cell periphery;GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0RCW7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R915-1", "uniprot_id": [ { "id": "M0R915_RAT", "url": "https://www.uniprot.org/uniprot/M0R915", "type": "external" } ], "mass": 160302.0, "length": 1414, "protein_name": "NLR family, apoptosis inhibitory protein 6", "gene_name": "Naip6", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Naip6", "gene_names_refseq": "", "protein_names_uniprotkb": "NLR family, apoptosis inhibitory protein 6", "protein_names_refseq": "", "tax_id": 10116, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); brain ischemia (Disease Ontology:DOID:2316)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0004869 cysteine-type endopeptidase inhibitor activity;GO:0120283 protein serine/threonine kinase binding", "go_cellular_component": "GO:0043025 neuronal cell body;GO:0043204 perikaryon;GO:0072557 IPAF inflammasome complex", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process;GO:0006954 inflammatory response;GO:0046330 positive regulation of JNK cascade;GO:0016045 detection of bacterium", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R915-1", "record_type": "protein", "filter_code": "0000000.0000010.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ABT4-1", "uniprot_id": [ { "id": "D4ABT4_RAT", "url": "https://www.uniprot.org/uniprot/D4ABT4", "type": "external" } ], "mass": 67181.0, "length": 598, "protein_name": "NADPH-dependent diflavin oxidoreductase 1", "gene_name": "Ndor1", "organism": "Rat", "refseq_name": "NADPH-dependent diflavin oxidoreductase 1", "refseq_ac": [ { "id": "NP_001101288", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101288", "type": "external" } ], "gene_names_uniprotkb": "Ndor1; NDOR1", "gene_names_refseq": "Ndor1", "protein_names_uniprotkb": "NADPH-dependent diflavin oxidoreductase 1; 1.18.1.-; NADPH-dependent FMN and FAD-containing oxidoreductase", "protein_names_refseq": "NADPH-dependent diflavin oxidoreductase 1", "tax_id": 10116, "disease": "", "pathway": " (rno:311799)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "19171935", "class_list": "", "function": "Analysis of the structure of NADPH-cytochrome P450 oxidoreductase in an open conformation capable of reducing cytochrome P450, [RefSeq, PubMed]; NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of CIAPIN1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the [2Fe-2S] cluster of CISD1 and activate this protein implicated in Fe/S cluster repair., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.18.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.18.1.-", "type": "external" } ], "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0016651 oxidoreductase activity, acting on NAD(P)H;GO:0010181 FMN binding;GO:0050661 NADP binding;GO:0160246 NADPH-iron-sulfur [2Fe-2S] protein oxidoreductase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0097361 cytosolic [4Fe-4S] assembly targeting complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0022900 electron transport chain", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4ABT4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B0BMT9-1", "uniprot_id": [ { "id": "B0BMT9_RAT", "url": "https://www.uniprot.org/uniprot/B0BMT9", "type": "external" } ], "mass": 50202.0, "length": 450, "protein_name": "Sulfide:quinone oxidoreductase, mitochondrial", "gene_name": "Sqor", "organism": "Rat", "refseq_name": "sulfide:quinone oxidoreductase, mitochondrial isoform 1", "refseq_ac": [ { "id": "NP_001041378", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001041378", "type": "external" } ], "gene_names_uniprotkb": "Sqor; Sqrdl", "gene_names_refseq": "Cc2-17; Sqor; Sqrdl", "protein_names_uniprotkb": "Sulfide:quinone oxidoreductase, mitochondrial; 1.8.5.8; Sulfide quinone oxidoreductase", "protein_names_refseq": "sulfide:quinone oxidoreductase, mitochondrial isoform 1; sulfide:quinone oxidoreductase, mitochondrial", "tax_id": 10116, "disease": "", "pathway": " (rno:691966); (R-RNO-1614517)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "22067608;25130143;28107627", "class_list": "", "function": "Catalyzes the oxidation of hydrogen sulfide with the help of a quinone, such as ubiquinone-10, giving rise to thiosulfate and ultimately to sulfane (molecular sulfur) atoms. Requires an additional electron acceptor; can use sulfite, sulfide or cyanide (in vitro). It is believed the in vivo electron acceptor is glutathione., [UniProtKB, UniProtKB, UniProtKB]; The present report demonstrates the presence and specific localization of SQRDL in various mammalian tissues., [RefSeq, PubMed]; The role of Sqor in hydrogen sulfide metabolism in the heart and liver, [RefSeq, PubMed]; We demonstrated that the SQRDL protein is expressed in neurons, oligodendrocytes, and endothelial cells, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1M5R5", "ec_number_list": [ { "id": "1.8.5.8", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.5.8", "type": "external" }, { "id": "2.8.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.1.1", "type": "external" } ], "go_molecular_function": "GO:0070224 sulfide:quinone oxidoreductase activity;GO:0048038 quinone binding;GO:0106436 glutathione-dependent sulfide quinone oxidoreductase activity;GO:0071949 FAD binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006790 sulfur compound metabolic process;GO:0070221 sulfide oxidation, using sulfide:quinone oxidoreductase", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "B0BMT9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZLK2-1", "uniprot_id": [ { "id": "D3ZLK2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZLK2", "type": "external" } ], "mass": 30405.0, "length": 274, "protein_name": "Ras-like protein family member 12", "gene_name": "Rasl12", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rasl12", "gene_names_refseq": "", "protein_names_uniprotkb": "Ras-like protein family member 12; 3.6.5.2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:315762)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.1", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0005525 GTP binding;GO:0003925 G protein activity;GO:0003924 GTPase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007264 small GTPase-mediated signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZLK2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1MAQ7-1", "uniprot_id": [ { "id": "F1MAQ7_RAT", "url": "https://www.uniprot.org/uniprot/F1MAQ7", "type": "external" } ], "mass": 266118.0, "length": 2446, "protein_name": "Protein SON", "gene_name": "Son", "organism": "Rat", "refseq_name": "protein SON isoform 1", "refseq_ac": [ { "id": "NP_001163798", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163798", "type": "external" } ], "gene_names_uniprotkb": "Son", "gene_names_refseq": "Son", "protein_names_uniprotkb": "Protein SON; Negative regulatory element-binding protein", "protein_names_refseq": "SON DNA-binding protein; Son DNA binding protein; Son cell proliferation protein; protein SON isoform 1", "tax_id": 10116, "disease": "ZTTK syndrome (Disease Ontology:DOID:0060953); congenital anomalies of kidney and urinary tract syndrome with or without hearing loss, abnormal ears, or developmental delay (Disease Ontology:DOID:0112359); congenital heart disease (Disease Ontology:DOID:1682)", "pathway": " (rno:304092)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003677 DNA binding;GO:0050733 RS domain binding", "go_cellular_component": "GO:0016607 nuclear speck", "go_biological_process": "GO:0043484 regulation of RNA splicing;GO:0051726 regulation of cell cycle;GO:0006397 mRNA processing;GO:0043066 negative regulation of apoptotic process;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1MAQ7-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1MAQ6-1", "uniprot_id": [ { "id": "F1MAQ6_RAT", "url": "https://www.uniprot.org/uniprot/F1MAQ6", "type": "external" } ], "mass": 89206.0, "length": 799, "protein_name": "Protein O-mannosyl-transferase TMTC4", "gene_name": "Tmtc4", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tmtc4", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein O-mannosyl-transferase TMTC4; 2.4.1.109; Transmembrane O-mannosyltransferase targeting cadherins 4; Transmembrane and tetratricopeptide repeat-containing 4", "protein_names_refseq": "", "tax_id": 10116, "disease": "autosomal recessive nonsyndromic deafness (Disease Ontology:DOID:0050565)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity;GO:0051117 ATPase binding;GO:0000030 mannosyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0007605 sensory perception of sound;GO:0030968 endoplasmic reticulum unfolded protein response;GO:0035269 protein O-linked glycosylation via mannose;GO:0032470 positive regulation of endoplasmic reticulum calcium ion concentration;GO:1905584 outer hair cell apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MAQ6-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZGN2-1", "uniprot_id": [ { "id": "D3ZGN2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZGN2", "type": "external" } ], "mass": 65606.0, "length": 593, "protein_name": "Copine-5", "gene_name": "Cpne5", "organism": "Rat", "refseq_name": "copine-5", "refseq_ac": [ { "id": "NP_001101086", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101086", "type": "external" } ], "gene_names_uniprotkb": "Cpne5", "gene_names_refseq": "Cpne5", "protein_names_uniprotkb": "Copine-5; Copine V", "protein_names_refseq": "copine 5 protein; copine V; copine-5", "tax_id": 10116, "disease": "", "pathway": " (rno:309650)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16641100;22673903", "class_list": "", "function": "Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005544 calcium-dependent phospholipid binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043025 neuronal cell body;GO:0043204 perikaryon;GO:0043005 neuron projection", "go_biological_process": "GO:1903861 positive regulation of dendrite extension;GO:0030154 cell differentiation;GO:0071277 cellular response to calcium ion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZGN2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F7F0U1-1", "uniprot_id": [ { "id": "F7F0U1_RAT", "url": "https://www.uniprot.org/uniprot/F7F0U1", "type": "external" } ], "mass": 63096.0, "length": 554, "protein_name": "Cytochrome P450 3A", "gene_name": "Cyp3a62", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cyp3a62; Cyp3a9", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytochrome P450 3A; 1.14.14.-", "protein_names_refseq": "", "tax_id": 10116, "disease": "alcohol-associated liver disease (Disease Ontology:DOID:0070658); familial Mediterranean fever (Disease Ontology:DOID:2987)", "pathway": " (R-RNO-211945); (R-RNO-211958); (R-RNO-211981); (R-RNO-5423646); (R-RNO-9027307); (R-RNO-9749641); (R-RNO-9754706); (R-RNO-9757110)", "pathway_count": 8, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.14.14.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.1", "type": "external" }, { "id": "1.14.14.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.-", "type": "external" }, { "id": "4.2.1.152", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.152", "type": "external" }, { "id": "1.14.13.n7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.n7", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0050649 testosterone 6-beta-hydroxylase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0070989 oxidative demethylation;GO:0008202 steroid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F7F0U1-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1MAD3-1", "uniprot_id": [ { "id": "F1MAD3_RAT", "url": "https://www.uniprot.org/uniprot/F1MAD3", "type": "external" } ], "mass": 466168.0, "length": 4292, "protein_name": "Polycystin-1", "gene_name": "Pkd1", "organism": "Rat", "refseq_name": "polycystin-1 precursor", "refseq_ac": [ { "id": "NP_001400942", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001400942", "type": "external" } ], "gene_names_uniprotkb": "Pkd1", "gene_names_refseq": "Pkd1", "protein_names_uniprotkb": "Polycystin-1", "protein_names_refseq": "polycystic kidney disease 1 homolog; polycystin-1 precursor", "tax_id": 10116, "disease": "polycystic liver disease (Disease Ontology:DOID:0050770); polycystic kidney disease (Disease Ontology:DOID:0080322); polycystic kidney disease 1 (Disease Ontology:DOID:0110858); autosomal recessive polycystic kidney disease (Disease Ontology:DOID:0110861); intracranial aneurysm (Disease Ontology:DOID:10941); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); autosomal dominant polycystic kidney disease (Disease Ontology:DOID:898)", "pathway": " (rno:24650); (R-RNO-5620916)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "29133434;29949809;33065236;34407229", "class_list": "", "function": "Component of a heteromeric calcium-permeable ion channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B. Both PKD1 and PKD2 are required for channel activity. Involved in renal tubulogenesis. Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Acts as a regulator of cilium length, together with PKD2. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. May be an ion-channel regulator. Involved in adhesive protein-protein and protein-carbohydrate interactions. Likely to be involved with polycystin-1-interacting protein 1 in the detection, sequestration and exocytosis of senescent mitochondria., [UniProtKB, UniProtKB, UniProtKB]; PKD1 alleviates oxidative stress-inhibited osteogenesis of rat bone marrow-derived mesenchymal stem cells through TAZ activation., [RefSeq, PubMed]; PKD1 enhances the stability of N-cadherin on cell membrane and promotes synapse morphogenesis and synaptic plasticity in an activity-dependent manner, [RefSeq, PubMed]; PKD1 mediates the PKC effects on KV11.1 and we found that PKD targets S284 in the N-terminus of the channel., [RefSeq, PubMed]; Polycystin-1 mitigates damage and regulates CTGF expression through AKT activation during cardiac ischemia/reperfusion., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030246 carbohydrate binding;GO:0005262 calcium channel activity;GO:0019901 protein kinase binding;GO:0019904 protein domain specific binding;GO:0044325 transmembrane transporter binding", "go_cellular_component": "GO:0002133 polycystin complex;GO:0005576 extracellular region;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane", "go_biological_process": "GO:0007507 heart development;GO:0001822 kidney development;GO:0006816 calcium ion transport;GO:0098609 cell-cell adhesion;GO:0009887 animal organ morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F1MAD3-1", "record_type": "protein", "filter_code": "0000000.0000111.001000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZFD8-1", "uniprot_id": [ { "id": "D3ZFD8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZFD8", "type": "external" } ], "mass": 35688.0, "length": 325, "protein_name": "TNF superfamily member 13b", "gene_name": "Tnfsf13b", "organism": "Rat", "refseq_name": "tumor necrosis factor ligand superfamily member 13B isoform X1", "refseq_ac": [ { "id": "XP_006253542", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006253542", "type": "external" } ], "gene_names_uniprotkb": "Tnfsf13b", "gene_names_refseq": "BAFF; RGD1561519; Tnfsf13b; Tnlg7a", "protein_names_uniprotkb": "TNF superfamily member 13b", "protein_names_refseq": "tumor necrosis factor ligand superfamily member 13B isoform X1", "tax_id": 10116, "disease": "Sjogren's syndrome (Disease Ontology:DOID:12894); IgA glomerulonephritis (Disease Ontology:DOID:2986)", "pathway": " (R-RNO-5668541); (R-RNO-5669034); (R-RNO-5676594)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0005164 tumor necrosis factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006955 immune response;GO:0002260 lymphocyte homeostasis;GO:0031295 T cell costimulation;GO:0050776 regulation of immune response;GO:0002636 positive regulation of germinal center formation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZFD8-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JV99-1", "uniprot_id": [ { "id": "A0A0G2JV99_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JV99", "type": "external" } ], "mass": 217336.0, "length": 1975, "protein_name": "Germinal-center associated nuclear protein", "gene_name": "Mcm3ap", "organism": "Rat", "refseq_name": "germinal-center associated nuclear protein", "refseq_ac": [ { "id": "NP_001421547", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421547", "type": "external" } ], "gene_names_uniprotkb": "Mcm3ap", "gene_names_refseq": "Mcm3ap", "protein_names_uniprotkb": "Germinal-center associated nuclear protein; 2.3.1.48", "protein_names_refseq": "80 kDa MCM3-associated protein; germinal-center associated nuclear protein; minichromosome maintenance deficient 3 associated protein", "tax_id": 10116, "disease": "", "pathway": " (rno:294339)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;35113004", "class_list": "", "function": "As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores. Through the acetylation of histones, affects the assembly of nucleosomes at immunoglobulin variable region genes and promotes the recruitment and positioning of transcription complex to favor DNA cytosine deaminase AICDA/AID targeting, hence promoting somatic hypermutations., [UniProtKB, UniProtKB, UniProtKB]; Long non-coding RNA MCM3AP antisense RNA 1 silencing upregulates microRNA-24-3p to accelerate proliferation and migration of vascular endothelial cells in myocardial infarction rats by reducing EIF4G2., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.-", "type": "external" } ], "go_molecular_function": "GO:0061733 protein-lysine-acetyltransferase activity;GO:0003676 nucleic acid binding;GO:0003682 chromatin binding;GO:0042393 histone binding;GO:0004402 histone acetyltransferase activity", "go_cellular_component": "GO:0005643 nuclear pore;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005694 chromosome;GO:0044615 nuclear pore nuclear basket", "go_biological_process": "GO:0015031 protein transport;GO:0051028 mRNA transport;GO:0002376 immune system process;GO:0016973 poly(A)+ mRNA export from nucleus;GO:0034728 nucleosome organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2JV99-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K5E4-1", "uniprot_id": [ { "id": "A0A0G2K5E4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K5E4", "type": "external" } ], "mass": 52403.0, "length": 480, "protein_name": "DnaJ homolog subfamily A member 3, mitochondrial", "gene_name": "Dnaja3", "organism": "Rat", "refseq_name": "dnaJ homolog subfamily A member 3, mitochondrial isoform 1", "refseq_ac": [ { "id": "NP_001033684", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033684", "type": "external" } ], "gene_names_uniprotkb": "Dnaja3", "gene_names_refseq": "Dnaja3; Tid-1", "protein_names_uniprotkb": "DnaJ homolog subfamily A member 3, mitochondrial; DnaJ protein Tid-1; Tumorous imaginal discs protein Tid56 homolog", "protein_names_refseq": "DnaJ (Hsp40) homolog, subfamily A, member 3; dnaJ homolog subfamily A member 3, mitochondrial isoform 1; dnaJ homolog subfamily A member 3, mitochondrial", "tax_id": 10116, "disease": "", "pathway": " (rno:360481)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "22016808;31081962;38843836", "class_list": "", "function": "Changes in cellular TID1 are a factor in the pathogenesis of Parkinson's disease, [RefSeq, PubMed]; Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma-mediated transcriptional activity. Isoform 2 may play a role in neuromuscular junction development as an effector of the MUSK signaling pathway., [UniProtKB, UniProtKB, UniProtKB]; Tid1-S attenuates LPS-induced cardiac hypertrophy and apoptosis through ER-a mediated modulation of p-PI3K/p-Akt signaling cascade., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005759 mitochondrial matrix;GO:0005829 cytosol;GO:0045211 postsynaptic membrane;GO:0005737 cytoplasm", "go_biological_process": "GO:0007528 neuromuscular junction development;GO:0042127 regulation of cell population proliferation;GO:0006915 apoptotic process;GO:0002682 regulation of immune system process;GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0G2K5E4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V7L1-1", "uniprot_id": [ { "id": "UTRN_RAT", "url": "https://www.uniprot.org/uniprot/G3V7L1", "type": "external" } ], "mass": 391312.0, "length": 3419, "protein_name": "Utrophin", "gene_name": "Utrn", "organism": "Rat", "refseq_name": "utrophin", "refseq_ac": [ { "id": "NP_037202", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037202", "type": "external" } ], "gene_names_uniprotkb": "Utrn; rCG_57340", "gene_names_refseq": "DRP-1; Utrn", "protein_names_uniprotkb": "Utrophin; DRP-1; Dystrophin-related protein 1", "protein_names_refseq": "dystrophin-related protein 1; utrophin (homologous to dystrophin); utrophin", "tax_id": 10116, "disease": "Duchenne muscular dystrophy (Disease Ontology:DOID:11723); ovarian cancer (Disease Ontology:DOID:2394); muscular dystrophy (Disease Ontology:DOID:9884)", "pathway": " (rno:25600); (R-RNO-9913351)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10545507;16641100;21192954;22228988;22673903;7890770", "class_list": "", "function": "Alterations in the immunoreactivities and expressions of beta-dystroglycan, utrophin, and laminin seem to correlate with angiogenesis rather than BBB disruption during cerebral hypoperfusion., [RefSeq, PubMed]; May play a role in anchoring the cytoskeleton to the plasma membrane., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; N-utro may be responsible for the anchoring of the cortical actin cytoskeleton to the membranes in muscle and other tissues., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005178 integrin binding;GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0016010 dystrophin-associated glycoprotein complex;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030426 growth cone;GO:0031594 neuromuscular junction", "go_biological_process": "GO:0007528 neuromuscular junction development;GO:0014894 response to denervation involved in regulation of muscle adaptation;GO:0001954 positive regulation of cell-matrix adhesion;GO:0099536 synaptic signaling", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "G3V7L1-1", "record_type": "protein", "filter_code": "0000000.0000111.001000.000000000000001000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R6E9-1", "uniprot_id": [ { "id": "M0R6E9_RAT", "url": "https://www.uniprot.org/uniprot/M0R6E9", "type": "external" } ], "mass": 23703.0, "length": 218, "protein_name": "CD300c molecule like 1", "gene_name": "Cd300c2; Cd300cl1; Cd300c; Igsf7l1; Igsf7", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cd300c2; Cd300cl1; Cd300c; Igsf7l1; Igsf7; AABR07030773.1; AABR07030796.1; Cd300c2; Cd300cl1; Igsf7 l1; Igsf7l1; Igsf7; LOC100909671; RGD1559482", "gene_names_refseq": "", "protein_names_uniprotkb": "CD300c molecule like 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:100909671)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0001819 positive regulation of cytokine production;GO:0002376 immune system process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R6E9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LM99-1", "uniprot_id": [ { "id": "F1LM99_RAT", "url": "https://www.uniprot.org/uniprot/F1LM99", "type": "external" } ], "mass": 109602.0, "length": 1004, "protein_name": "PHD finger protein 12", "gene_name": "Phf12", "organism": "Rat", "refseq_name": "PHD finger protein 12", "refseq_ac": [ { "id": "NP_001013135", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013135", "type": "external" } ], "gene_names_uniprotkb": "Phf12", "gene_names_refseq": "Phf12", "protein_names_uniprotkb": "PHD finger protein 12; PHD factor 1", "protein_names_refseq": "PHD finger protein 12", "tax_id": 10116, "disease": "", "pathway": " (rno:303274)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity;GO:0035091 phosphatidylinositol binding;GO:0001222 transcription corepressor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0017053 transcription repressor complex;GO:0070822 Sin3-type complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LM99-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZZN2-1", "uniprot_id": [ { "id": "D3ZZN2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZZN2", "type": "external" } ], "mass": 78529.0, "length": 691, "protein_name": "RAS guanyl releasing protein 3", "gene_name": "Rasgrp3", "organism": "Rat", "refseq_name": "ras guanyl-releasing protein 3", "refseq_ac": [ { "id": "NP_001386473", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386473", "type": "external" } ], "gene_names_uniprotkb": "Rasgrp3", "gene_names_refseq": "Rasgrp3", "protein_names_uniprotkb": "RAS guanyl releasing protein 3", "protein_names_refseq": "RAS guanyl releasing protein 3 (calcium and DAG-regulated); ras guanyl-releasing protein 3", "tax_id": 10116, "disease": "hypertension (Disease Ontology:DOID:10763)", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "15737652;18588530", "class_list": "", "function": "Functions as a calcium- and diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. Activates the Erk/MAP kinase cascade. Regulates T-cell/B-cell development, homeostasis and differentiation by coupling T-lymphocyte/B-lymphocyte antigen receptors to Ras. Regulates NK cell cytotoxicity and ITAM-dependent cytokine production by activation of Ras-mediated ERK and JNK pathways. Functions in mast cell degranulation and cytokine secretion, regulating FcERI-evoked allergic responses. May also function in differentiation of other cell types. Proto-oncogene, which promotes T-cell lymphomagenesis when its expression is deregulated., [UniProtKB, UniProtKB]; These results indicate that RasGRP3 is implicated in phorbol ester-induced, PKC-independent exocytosis., [RefSeq, PubMed]; Together these data demonstrate a novel mechanism in which the balance between stability and plasticity in dendritic spines depends on binding of drebrin to actin filaments in a manner that is regulated by Ras., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding;GO:0005509 calcium ion binding;GO:0019900 kinase binding;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0032045 guanyl-nucleotide exchange factor complex", "go_biological_process": "GO:0007265 Ras protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZZN2-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AAK2-1", "uniprot_id": [ { "id": "D4AAK2_RAT", "url": "https://www.uniprot.org/uniprot/D4AAK2", "type": "external" } ], "mass": 47753.0, "length": 419, "protein_name": "Nucleolar and spindle associated protein 1", "gene_name": "Nusap1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Nusap1", "gene_names_refseq": "", "protein_names_uniprotkb": "Nucleolar and spindle associated protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:311336)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005874 microtubule;GO:0072686 mitotic spindle;GO:0005634 nucleus;GO:0005819 spindle", "go_biological_process": "GO:0007076 mitotic chromosome condensation;GO:0000281 mitotic cytokinesis;GO:0040001 establishment of mitotic spindle localization;GO:0045840 positive regulation of mitotic nuclear division;GO:0000070 mitotic sister chromatid segregation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4AAK2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZQA1-1", "uniprot_id": [ { "id": "D3ZQA1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZQA1", "type": "external" } ], "mass": 68638.0, "length": 604, "protein_name": "Polypeptide N-acetylgalactosaminyltransferase", "gene_name": "Galnt9", "organism": "Rat", "refseq_name": "polypeptide N-acetylgalactosaminyltransferase 9 isoform A", "refseq_ac": [ { "id": "NP_001116116", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116116", "type": "external" } ], "gene_names_uniprotkb": "Galnt9", "gene_names_refseq": "Galnt9", "protein_names_uniprotkb": "Polypeptide N-acetylgalactosaminyltransferase; 2.4.1.-; Protein-UDP acetylgalactosaminyltransferase", "protein_names_refseq": "UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9; polypeptide N-acetylgalactosaminyltransferase 9 isoform A", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-913709)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Does not glycosylate apomucin or SDC3., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.-", "type": "external" }, { "id": "2.4.1.41", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.41", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0006493 protein O-linked glycosylation", "synthesized_glycan_count": 7434, "hit_score": 0.1, "record_id": "D3ZQA1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K9X2-1", "uniprot_id": [ { "id": "A0A0G2K9X2_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K9X2", "type": "external" } ], "mass": 46284.0, "length": 412, "protein_name": "43 kDa receptor-associated protein of the synapse", "gene_name": "Rapsn", "organism": "Rat", "refseq_name": "43 kDa receptor-associated protein of the synapse isoform 1", "refseq_ac": [ { "id": "NP_001386657", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386657", "type": "external" } ], "gene_names_uniprotkb": "Rapsn", "gene_names_refseq": "Rapsn; rapsyn", "protein_names_uniprotkb": "43 kDa receptor-associated protein of the synapse; 43 kDa postsynaptic protein; Acetylcholine receptor-associated 43 kDa protein", "protein_names_refseq": "43 kDa receptor-associated protein of the synapse isoform 1; 43 kDa receptor-associated protein of the synapse; nicotinic acetylcholine receptor-associated 46K protein; receptor-associated protein of the synapse, 43 kDa", "tax_id": 10116, "disease": "congenital myasthenic syndrome 11 (Disease Ontology:DOID:0110675); fetal akinesia deformation sequence syndrome 2 (Disease Ontology:DOID:0111378)", "pathway": " (rno:362161)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12486121", "class_list": "", "function": "Postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin., [UniProtKB, UniProtKB]; Rapsyn binds to acetylcholine receptor at the cell surface, and its recruitment is induced by agrin GeneRIF: rapsyn binds to AChR at the cell surface, and its recruitment is induced by agrin., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0033130 acetylcholine receptor binding;GO:0043495 protein-membrane adaptor activity;GO:0030674 protein-macromolecule adaptor activity;GO:0035255 ionotropic glutamate receptor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0045202 synapse;GO:0005794 Golgi apparatus;GO:0005856 cytoskeleton;GO:0005886 plasma membrane", "go_biological_process": "GO:0007268 chemical synaptic transmission;GO:0007271 synaptic transmission, cholinergic;GO:0007528 neuromuscular junction development;GO:0043525 positive regulation of neuron apoptotic process;GO:0071340 skeletal muscle acetylcholine-gated channel clustering", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K9X2-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K189-1", "uniprot_id": [ { "id": "A0A0G2K189_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K189", "type": "external" } ], "mass": 47769.0, "length": 418, "protein_name": "Secernin 3", "gene_name": "Scrn3", "organism": "Rat", "refseq_name": "secernin-3", "refseq_ac": [ { "id": "NP_001386495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386495", "type": "external" } ], "gene_names_uniprotkb": "Scrn3", "gene_names_refseq": "Scrn3", "protein_names_uniprotkb": "Secernin 3", "protein_names_refseq": "secernin-3", "tax_id": 10116, "disease": "", "pathway": " (rno:311731)", 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"reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016805 dipeptidase activity;GO:0070004 cysteine-type exopeptidase activity", "go_cellular_component": "", "go_biological_process": "GO:0006508 proteolysis;GO:0050965 detection of temperature stimulus involved in sensory perception of pain", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K189-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZWU1-1", "uniprot_id": [ { "id": "D3ZWU1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZWU1", "type": "external" } ], "mass": 79660.0, "length": 725, "protein_name": "Bromodomain containing 3", "gene_name": "Brd3", "organism": "Rat", "refseq_name": "bromodomain-containing protein 3 isoform b", "refseq_ac": [ { "id": "NP_001102045", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102045", "type": "external" } ], "gene_names_uniprotkb": "Brd3", "gene_names_refseq": "Brd3", "protein_names_uniprotkb": "Bromodomain containing 3", "protein_names_refseq": "bromodomain-containing protein 3 isoform b; bromodomain-containing protein 3", "tax_id": 10116, "disease": "", "pathway": " (rno:362092)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0140693 molecular condensate scaffold activity;GO:0062072 histone H3K9me2/3 reader activity;GO:0106222 lncRNA binding;GO:0140038 histone H3K27cr reader activity;GO:0140017 histone H3K18cr reader activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000785 chromatin;GO:0005634 nucleus", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0071168 protein localization to chromatin;GO:0035987 endodermal cell differentiation;GO:0006338 chromatin remodeling;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZWU1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B5DF29-1", "uniprot_id": [ { "id": "B5DF29_RAT", "url": "https://www.uniprot.org/uniprot/B5DF29", "type": "external" } ], "mass": 39365.0, "length": 347, "protein_name": "Activator 1 subunit 5", "gene_name": "Rfc5", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rfc5", "gene_names_refseq": "", "protein_names_uniprotkb": "Activator 1 subunit 5", "protein_names_refseq": "", "tax_id": 10116, "disease": "Williams-Beuren syndrome (Disease Ontology:DOID:1928)", "pathway": " (rno:304528); (R-RNO-110312); (R-RNO-110314); (R-RNO-110320); (R-RNO-174411); (R-RNO-176187); (R-RNO-5651801); (R-RNO-5655862); (R-RNO-5656121); (R-RNO-5656169); (R-RNO-5685938); (R-RNO-5685942); (R-RNO-5693537); (R-RNO-5693607); (R-RNO-5696397); (R-RNO-5696400); (R-RNO-6782135); (R-RNO-6782210); (R-RNO-6804756); (R-RNO-69091); (R-RNO-69473)", "pathway_count": 21, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Subunit of the replication factor C (RFC) complex which acts during elongation of primed DNA templates by DNA polymerases delta and epsilon, and is necessary for ATP-dependent loading of proliferating cell nuclear antigen (PCNA) onto primed DNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1LQL0", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0019899 enzyme binding;GO:0016887 ATP hydrolysis activity;GO:0003689 DNA clamp loader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0031390 Ctf18 RFC-like complex;GO:0005663 DNA replication factor C complex;GO:0031389 Rad17 RFC-like complex", "go_biological_process": "GO:0006281 DNA repair;GO:1900264 positive regulation of DNA-directed DNA polymerase activity;GO:0006261 DNA-templated DNA replication;GO:0006260 DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B5DF29-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LVG7-1", "uniprot_id": [ { "id": "F1LVG7_RAT", "url": "https://www.uniprot.org/uniprot/F1LVG7", "type": "external" } ], "mass": 46014.0, "length": 401, "protein_name": "AADACL2 family member 3 like 1", "gene_name": "Aadacl2fm3", "organism": "Rat", "refseq_name": "uncharacterized protein LOC295072", "refseq_ac": [ { "id": "NP_001099906", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099906", "type": "external" } ], "gene_names_uniprotkb": "Aadacl2fm3; Aadacl2fm3l1; RGD1560324", "gene_names_refseq": "Aadacl2fm3; RGD1560324", "protein_names_uniprotkb": "AADACL2 family member 3 like 1", "protein_names_refseq": "uncharacterized protein LOC295072", "tax_id": 10116, "disease": "", "pathway": " (rno:295072)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, 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"kg_view_protein": true }, { "uniprot_canonical_ac": "D4AEF5-1", "uniprot_id": [ { "id": "D4AEF5_RAT", "url": "https://www.uniprot.org/uniprot/D4AEF5", "type": "external" } ], "mass": 138906.0, "length": 1249, "protein_name": "Zinc finger MYM-type containing 6", "gene_name": "Zmym6", "organism": "Rat", "refseq_name": "zinc finger MYM-type protein 6", "refseq_ac": [ { "id": "NP_001102151", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102151", "type": "external" } ], "gene_names_uniprotkb": "Zmym6", "gene_names_refseq": "RGD1561833; Zmym6", "protein_names_uniprotkb": "Zinc finger MYM-type containing 6", "protein_names_refseq": "zinc finger MYM-type protein 6; zinc finger, MYM-type 6", "tax_id": 10116, "disease": "", "pathway": " (rno:362602)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, 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"ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AEF5-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZSP1-1", "uniprot_id": [ { "id": "D3ZSP1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZSP1", "type": "external" } ], "mass": 10761.0, "length": 92, "protein_name": "Small nuclear ribonucleoprotein E", "gene_name": "Snrpepl2; Snrpe", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Snrpepl2; Snrpe; AC096024.2; Snrpep2; Snrpepl2", "gene_names_refseq": "", "protein_names_uniprotkb": "Small nuclear ribonucleoprotein E; Sm protein E; snRNP-E", "protein_names_refseq": "", "tax_id": 10116, "disease": "lupus nephritis (Disease Ontology:DOID:0080162); hypotrichosis 1 (Disease Ontology:DOID:0110698); hypotrichosis 11 (Disease Ontology:DOID:0110708); prostate cancer (Disease Ontology:DOID:10283); lung adenocarcinoma (Disease Ontology:DOID:3910); hepatocellular carcinoma (Disease Ontology:DOID:684); neuroblastoma (Disease Ontology:DOID:769); nasopharynx carcinoma (Disease Ontology:DOID:9261); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (rno:100360682); (rno:100362099); (R-RNO-111367); (R-RNO-191859); (R-RNO-72163); (R-RNO-72165); (R-RNO-73856); (R-RNO-77588); (R-RNO-9770562); (R-RNO-9943411)", "pathway_count": 10, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone 3'-end processing., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:1990446 U1 snRNP binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0005829 cytosol;GO:0005686 U2 snRNP;GO:0034715 pICln-Sm protein complex;GO:0071011 precatalytic spliceosome", "go_biological_process": "GO:0000387 spliceosomal snRNP assembly;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZSP1-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0RBT9-1", "uniprot_id": [ { "id": "M0RBT9_RAT", "url": "https://www.uniprot.org/uniprot/M0RBT9", "type": "external" } ], "mass": 102155.0, "length": 882, "protein_name": "Tubulin tyrosine ligase like 7", "gene_name": "Ttll7", "organism": "Rat", "refseq_name": "tubulin tyrosine ligase like 7 isoform b", "refseq_ac": [ { "id": "NP_001420093", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001420093", "type": "external" } ], "gene_names_uniprotkb": "Ttll7", "gene_names_refseq": "RGD1566117; Ttll7", "protein_names_uniprotkb": "Tubulin tyrosine ligase like 7", "protein_names_refseq": "tubulin polyglutamylase TTLL7-like; tubulin polyglutamylase TTLL7; tubulin tyrosine ligase like 7 isoform b; tubulin tyrosine ligase-like family, member 7", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-8955332)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16901895", "class_list": "", "function": "TTLL7 is a mammalian beta-tubulin polyglutamylase required for growth of MAP2-positive neurites, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070740 tubulin-glutamic acid ligase activity;GO:0005524 ATP binding;GO:0015631 tubulin binding;GO:0048487 beta-tubulin binding;GO:0043014 alpha-tubulin binding", "go_cellular_component": "GO:0036064 ciliary basal body;GO:0097731 9+0 non-motile cilium", "go_biological_process": "GO:0000226 microtubule cytoskeleton organization;GO:0018095 protein polyglutamylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "M0RBT9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0C0-1", "uniprot_id": [ { "id": "A0A0G2K0C0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0C0", "type": "external" } ], "mass": 65500.0, "length": 590, "protein_name": "Fucose-1-phosphate guanylyltransferase", "gene_name": "Fpgt", "organism": "Rat", "refseq_name": "fucose-1-phosphate guanylyltransferase isoform 1", "refseq_ac": [ { "id": "NP_955788", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_955788", "type": "external" } ], "gene_names_uniprotkb": "Fpgt", "gene_names_refseq": "Fpgt", "protein_names_uniprotkb": "Fucose-1-phosphate guanylyltransferase", "protein_names_refseq": "fucose-1-phosphate guanylyltransferase isoform 1; gdp-L-fucose pyrophosphorylase", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-6787639)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000166 nucleotide binding;GO:0016772 transferase activity, transferring phosphorus-containing groups;GO:0047341 fucose-1-phosphate guanylyltransferase activity", "go_cellular_component": "", "go_biological_process": "GO:0042350 GDP-L-fucose biosynthetic process;GO:0042352 GDP-L-fucose salvage;GO:0042354 L-fucose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K0C0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M652-1", "uniprot_id": [ { "id": "F1M652_RAT", "url": "https://www.uniprot.org/uniprot/F1M652", "type": "external" } ], "mass": 55675.0, "length": 509, "protein_name": "Fc receptor-like 2", "gene_name": "Fcrl2", "organism": "Rat", "refseq_name": "Fc receptor-like 2 precursor", "refseq_ac": [ { "id": "NP_001101172", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101172", "type": "external" } ], "gene_names_uniprotkb": "Fcrl2; Fcrls", "gene_names_refseq": "Fcrl2; Fcrls; Msr2", "protein_names_uniprotkb": "Fc receptor-like 2", "protein_names_refseq": "Fc receptor-like 2 precursor; Fc receptor-like S, scavenger receptor; macrophage scavenger receptor 2", "tax_id": 10116, "disease": "", "pathway": " (rno:310694)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0035591 signaling adaptor activity;GO:0019903 protein phosphatase binding", "go_cellular_component": "GO:0009986 cell surface;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006955 immune response;GO:0007166 cell surface receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M652-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M6D3-1", "uniprot_id": [ { "id": "F1M6D3_RAT", "url": "https://www.uniprot.org/uniprot/F1M6D3", "type": "external" } ], "mass": 49741.0, "length": 439, "protein_name": "Transmembrane protease serine", "gene_name": "Tmprss11f", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tmprss11f", "gene_names_refseq": "", "protein_names_uniprotkb": "Transmembrane protease serine; 3.4.21.-", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0008236 serine-type peptidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0016485 protein processing;GO:0061436 establishment of skin barrier", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M6D3-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M6J5-1", "uniprot_id": [ { "id": "F1M6J5_RAT", "url": "https://www.uniprot.org/uniprot/F1M6J5", "type": "external" } ], "mass": 93362.0, "length": 824, "protein_name": "Jade family PHD finger 3", "gene_name": "Jade3", "organism": "Rat", "refseq_name": "protein Jade-3", "refseq_ac": [ { "id": "NP_001258194", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258194", "type": "external" } ], "gene_names_uniprotkb": "Jade3", "gene_names_refseq": "Jade3; 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Acts downstream of the ribosome-associated quality control (RQC) pathway to release non-ubiquitinated nascent chains from 60S and 80S ribosome-nascent chain complexes. 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network membrane;GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0007283 spermatogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1M8G0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000011001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M8N1-1", "uniprot_id": [ { "id": "F1M8N1_RAT", "url": "https://www.uniprot.org/uniprot/F1M8N1", "type": "external" } ], "mass": 33856.0, "length": 301, "protein_name": "MAS related GPR family member G like 1", "gene_name": "Mrgprgl1", "organism": "Rat", "refseq_name": "mas-related G-protein coupled receptor member G", "refseq_ac": [ { "id": "XP_006231028", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006231028", "type": "external" } ], "gene_names_uniprotkb": "Mrgprgl1; RGD1562011", "gene_names_refseq": "Mrgprgl1", "protein_names_uniprotkb": "MAS related GPR family member G like 1", "protein_names_refseq": "mas-related 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cell cycle regulator", "gene_name": "Zyg11b", "organism": "Rat", "refseq_name": "protein zyg-11 homolog B", "refseq_ac": [ { "id": "NP_001413923", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001413923", "type": "external" } ], "gene_names_uniprotkb": "Zyg11b", "gene_names_refseq": "RGD1307814; Zyg11b", "protein_names_uniprotkb": "Zyg-11 family member B, cell cycle regulator", "protein_names_refseq": "protein zyg-11 homolog B; zyg-11 homolog B; zyg-ll homolog B", "tax_id": 10116, "disease": "", "pathway": " (rno:362559)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, 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process;GO:0006515 protein quality control for misfolded or incompletely synthesized proteins", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M8P2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M9D3-1", "uniprot_id": [ { "id": "F1M9D3_RAT", "url": "https://www.uniprot.org/uniprot/F1M9D3", "type": "external" } ], "mass": 42294.0, "length": 379, "protein_name": "Sphingosine-1-phosphate receptor 3", "gene_name": "S1pr3", "organism": "Rat", "refseq_name": "sphingosine 1-phosphate receptor 3", "refseq_ac": [ { "id": "NP_001258072", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258072", "type": "external" } ], "gene_names_uniprotkb": "S1pr3", "gene_names_refseq": "Edg3l; Edg3; S1pr3; lpb3", "protein_names_uniprotkb": "Sphingosine-1-phosphate receptor 3", "protein_names_refseq": "cardiac sphingosine-1-phosphate specific receptor; endothelial differentiation, sphingolipid G-protein-coupled receptor, 3; sphingosine 1-phosphate receptor 3", "tax_id": 10116, "disease": "", "pathway": " (rno:306792); (R-RNO-418594); (R-RNO-419408); (R-RNO-9009391)", "pathway_count": 4, "publication_count": 5, "publication_id_list": "18535287;25869501;28634078;29266713;29536648", "class_list": "", "function": "A pro-migratory role was determined for S1PR3 in vascular smooth muscle cells., [RefSeq, PubMed]; Astrocytes regulate the expression of S1pR3 in oligodendrocyte progenitor cells via Cx47, which could be a valuable approach for promoting oligodendrocyte progenitor cells proliferation., [RefSeq, PubMed]; S1P (sphingosine-1-phosphate receptor)1 and S1P3 receptors promote, whereas S1P2 receptors antagonize, smooth muscle cell proliferation and phenotypic modulation in vitro in response to sphingosine-1-phosphate (S1P), or in vivo after vascular injury Erratum:[Arterioscler Thromb Vasc Biol. 2011 Jan;31(1):e3], [RefSeq, PubMed]; Testosterone regulates the expression and functional activity of sphingosine-1-phosphate receptors in the rat corpus cavernosum., [RefSeq, PubMed]; This study reveals that pFTY720 depends on S1PR3 to protect astrocytes against OGD-induced neuroinflammation, due to inhibiting TLR2/4-PI3K-NFkappaB signalling pathway., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0005178 integrin binding;GO:0038036 sphingosine-1-phosphate receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0098793 presynapse", "go_biological_process": "GO:0032651 regulation of interleukin-1 beta production;GO:0006954 inflammatory response;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007219 Notch signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F1M9D3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M9H4-1", "uniprot_id": [ { "id": "F1M9H4_RAT", "url": "https://www.uniprot.org/uniprot/F1M9H4", "type": "external" } ], "mass": 288943.0, "length": 2691, "protein_name": "Zinc finger protein 40", "gene_name": "Hivep1", "organism": "Rat", "refseq_name": "zinc finger protein 40 isoform X1", "refseq_ac": [ { "id": "XP_038951236", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038951236", "type": "external" } ], "gene_names_uniprotkb": "Hivep1", "gene_names_refseq": "Hivep1", "protein_names_uniprotkb": "Zinc finger protein 40", "protein_names_refseq": "zinc finger protein 40 isoform X1", "tax_id": 10116, "disease": "juvenile polyposis syndrome (Disease Ontology:DOID:0050787); Alzheimer's disease (Disease Ontology:DOID:10652)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0016604 nuclear body", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1M9H4-1", "record_type": "protein", "filter_code": "0000000.0000110.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M9T2-1", "uniprot_id": [ { "id": "F1M9T2_RAT", "url": "https://www.uniprot.org/uniprot/F1M9T2", "type": "external" } ], "mass": 99781.0, "length": 894, "protein_name": "Poly [ADP-ribose] polymerase", "gene_name": "Parp8", "organism": "Rat", "refseq_name": "protein mono-ADP-ribosyltransferase PARP8", "refseq_ac": [ { "id": "NP_001413998", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001413998", "type": "external" } ], "gene_names_uniprotkb": "Parp8", "gene_names_refseq": "Parp8", "protein_names_uniprotkb": "Poly [ADP-ribose] polymerase; 2.4.2.-; PARP", "protein_names_refseq": "poly [ADP-ribose] polymerase 8; protein mono-ADP-ribosyltransferase PARP8", "tax_id": 10116, "disease": "", "pathway": " (rno:294762)", 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"0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1MA19-1", "uniprot_id": [ { "id": "F1MA19_RAT", "url": "https://www.uniprot.org/uniprot/F1MA19", "type": "external" } ], "mass": 23586.0, "length": 209, "protein_name": "Ephrin A2", "gene_name": "Efna2", "organism": "Rat", "refseq_name": "ephrin-A2 precursor", "refseq_ac": [ { "id": "NP_001162141", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162141", "type": "external" } ], "gene_names_uniprotkb": "Efna2", "gene_names_refseq": "Efna2", "protein_names_uniprotkb": "Ephrin A2", "protein_names_refseq": "ephrin A-2; ephrin-A2 precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:84358); (R-RNO-2682334); (R-RNO-3928663); (R-RNO-3928665)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "12077243;14667581;17328773;22147308", "class_list": "", "function": "Ephrin A2 expression is restricted to the adult thymic medullary epithelial cells and some perivascular and peritrabecular areas., [RefSeq, PubMed]; Ephrin-A2, in concert with one or more Eph receptors, may be postnatally involved in arbor development of thalamocortical axons at cortical layer IV boundaries., [RefSeq, PubMed]; It is notable that the up-regulation of ephrin mRNAs occurs during the reorganization in the deafferented hippocampus, suggesting that ephrins may be involved in the plasticity events of the adult brain after lesion., [RefSeq, PubMed]; The repulsive ephrin-A2 environment offers at least a partial explanation for the observation that only a limited number of retinal ganglion cell axons can exit nerve graft to enter target central nervous system tissue., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046875 ephrin receptor binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031594 neuromuscular junction;GO:0043204 perikaryon;GO:0098552 side of membrane", "go_biological_process": "GO:0030316 osteoclast differentiation;GO:0042472 inner ear morphogenesis;GO:0048013 ephrin receptor signaling pathway;GO:0046849 bone remodeling;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F1MA19-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1MA70-1", "uniprot_id": [ { "id": "F1MA70_RAT", "url": "https://www.uniprot.org/uniprot/F1MA70", "type": "external" } ], "mass": 138928.0, "length": 1237, "protein_name": "Cation-transporting ATPase", "gene_name": "Atp13a5", "organism": "Rat", "refseq_name": "probable cation-transporting ATPase 13A5 isoform X1", "refseq_ac": [ { "id": "XP_038944228", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038944228", "type": "external" } ], "gene_names_uniprotkb": "Atp13a5", "gene_names_refseq": "Atp13a5; RGD1306792", "protein_names_uniprotkb": "Cation-transporting ATPase; 7.2.2.-", "protein_names_refseq": "probable cation-transporting ATPase 13A5 isoform X1", "tax_id": 10116, "disease": "Kufor-Rakeb syndrome (Disease Ontology:DOID:0060556); juvenile-onset Parkinson's disease (Disease Ontology:DOID:0060893); Parkinson's disease (Disease Ontology:DOID:14330); neuronal ceroid lipofuscinosis (Disease Ontology:DOID:14503); hereditary spastic paraplegia (Disease Ontology:DOID:2476); amyotrophic lateral sclerosis (Disease Ontology:DOID:332)", "pathway": " (R-RNO-936837)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.9.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.9.1.1", "type": "external" }, { "id": "6.1.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" } ], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity;GO:0015662 P-type ion transporter activity", "go_cellular_component": "GO:0031902 late endosome membrane;GO:0016020 membrane", "go_biological_process": "GO:0006874 intracellular calcium ion homeostasis;GO:1902047 polyamine transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MA70-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1MAA4-1", "uniprot_id": [ { "id": "F1MAA4_RAT", "url": "https://www.uniprot.org/uniprot/F1MAA4", "type": "external" } ], "mass": 127602.0, "length": 1173, "protein_name": "Polyamine-transporting ATPase 13A2", "gene_name": "Atp13a2", "organism": "Rat", "refseq_name": "polyamine-transporting ATPase 13A2 isoform 1", "refseq_ac": [ { "id": "NP_001424084", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001424084", "type": "external" } ], "gene_names_uniprotkb": "Atp13a2", "gene_names_refseq": "Atp13a2; RGD1307977", "protein_names_uniprotkb": "Polyamine-transporting ATPase 13A2", "protein_names_refseq": "ATPase type 13A2; polyamine-transporting ATPase 13A2 isoform 1; polyamine-transporting ATPase 13A2; probable cation-transporting ATPase 13A2", "tax_id": 10116, "disease": "Kufor-Rakeb syndrome (Disease Ontology:DOID:0060556); juvenile-onset Parkinson's disease (Disease Ontology:DOID:0060893); hereditary spastic paraplegia 78 (Disease Ontology:DOID:0112348); Parkinson's disease (Disease Ontology:DOID:14330); neuronal ceroid lipofuscinosis (Disease Ontology:DOID:14503); hereditary spastic paraplegia (Disease Ontology:DOID:2476); amyotrophic lateral sclerosis (Disease Ontology:DOID:332)", "pathway": " (R-RNO-936837)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21724849;27057733", "class_list": "", "function": "ATPase which acts as a lysosomal polyamine exporter with high affinity for spermine. Also stimulates cellular uptake of polyamines and protects against polyamine toxicity. Plays a role in intracellular cation homeostasis and the maintenance of neuronal integrity. Contributes to cellular zinc homeostasis. Confers cellular protection against Mn(2+) and Zn(2+) toxicity and mitochondrial stress. Required for proper lysosomal and mitochondrial maintenance. Regulates the autophagy-lysosome pathway through the control of SYT11 expression at both transcriptional and post-translational levels. Facilitates recruitment of deacetylase HDAC6 to lysosomes to deacetylate CTTN, leading to actin polymerization, promotion of autophagosome-lysosome fusion and completion of autophagy. Promotes secretion of exosomes as well as secretion of SCNA via exosomes. Plays a role in lipid homeostasis., [UniProtKB, UniProtKB, UniProtKB]; Pink1 -/- rats show significantly decreased levels of Atp13a2, a transmembrane lysosomal P5-type ATPase suggesting a potential mechanism for the observed abnormal aggregation., [RefSeq, PubMed]; Regulation of intracellular manganese homeostasis by Kufor-Rakeb syndrome-associated ATP13A2 protein., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0080025 phosphatidylinositol-3,5-bisphosphate binding;GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0043025 neuronal cell body;GO:0005764 lysosome;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:1903710 spermine transmembrane transport;GO:0010628 positive regulation of gene expression;GO:0055088 lipid homeostasis;GO:0006874 intracellular calcium ion homeostasis;GO:0006879 intracellular iron ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1MAA4-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1MAM8-1", "uniprot_id": [ { "id": "F1MAM8_RAT", "url": "https://www.uniprot.org/uniprot/F1MAM8", "type": "external" } ], "mass": 91426.0, "length": 824, "protein_name": "Probable ATP-dependent RNA helicase DDX20", "gene_name": "Ddx20", "organism": "Rat", "refseq_name": "probable ATP-dependent RNA helicase DDX20", "refseq_ac": [ { "id": "NP_001178640", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178640", "type": "external" } ], "gene_names_uniprotkb": "Ddx20", "gene_names_refseq": "Ddx20; Dp103", "protein_names_uniprotkb": "Probable ATP-dependent RNA helicase DDX20; 3.6.1.15; 3.6.4.13; Component of gems 3; DEAD box protein 20; DEAD box protein DP 103; Gemin-3", "protein_names_refseq": "DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20, 103kD; probable ATP-dependent RNA helicase DDX20", "tax_id": 10116, "disease": "", "pathway": " (rno:84473); (R-RNO-191859)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate. Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP. May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.1.1.320", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.320", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.9.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.9.1.1", "type": "external" }, { "id": "6.1.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.4.21.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.-", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0019904 protein domain specific 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Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0046872 metal ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0002930 trabecular meshwork development;GO:0042048 olfactory behavior;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007613 memory", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "G3V877-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V897-1", "uniprot_id": [ { "id": "G3V897_RAT", "url": "https://www.uniprot.org/uniprot/G3V897", "type": "external" } ], "mass": 133338.0, "length": 1173, "protein_name": "RNA polymerase-associated protein CTR9 homolog", "gene_name": "Ctr9", "organism": "Rat", "refseq_name": "RNA polymerase-associated protein CTR9 homolog", "refseq_ac": [ { "id": "NP_001094131", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094131", "type": "external" } ], "gene_names_uniprotkb": "Ctr9", "gene_names_refseq": "Ctr9; Sh2bp1", "protein_names_uniprotkb": "RNA polymerase-associated protein CTR9 homolog; SH2 domain-binding protein 1", "protein_names_refseq": "CTR9 homolog, Paf1/RNA polymerase II complex component; Ctr9, Paf1/RNA polymerase II complex component, homolog; RNA polymerase-associated protein CTR9 homolog; SH2 domain binding protein 1 (tetratricopeptide repeat containing)", "tax_id": 10116, "disease": "", "pathway": " (rno:293184); (R-RNO-112382); (R-RNO-674695); (R-RNO-75955); (R-RNO-8866654); (R-RNO-9943411)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "22673903;26048990", "class_list": "", "function": "Ctr9, formerly identified as a nuclei protein, interacts with the dopamine transporter in the cytoplasmic compartment., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042169 SH2 domain binding;GO:0000993 RNA polymerase II complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0016607 nuclear speck;GO:0000791 euchromatin;GO:0016593 Cdc73/Paf1 complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0071222 cellular response to lipopolysaccharide;GO:0001829 trophectodermal cell differentiation;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "G3V897-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V8V4-1", "uniprot_id": [ { "id": "G3V8V4_RAT", "url": "https://www.uniprot.org/uniprot/G3V8V4", "type": "external" } ], "mass": 44951.0, "length": 380, "protein_name": "Ceramide synthase 2", "gene_name": "Cers2", "organism": "Rat", "refseq_name": "ceramide synthase 2", "refseq_ac": [ { "id": "NP_001028872", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028872", "type": "external" } ], "gene_names_uniprotkb": "Cers2", "gene_names_refseq": "Cers2; Lass2", "protein_names_uniprotkb": "Ceramide synthase 2", "protein_names_refseq": "LAG1 homolog, ceramide synthase 2; ceramide synthase 2", "tax_id": 10116, "disease": "sciatic neuropathy (Disease Ontology:DOID:11446)", "pathway": " (rno:310667); (R-RNO-1660661)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "22393241;22673903", "class_list": "", "function": "Sciatic nerve injury promotes Schwann cell proliferation and migration through the regulation of miR-221/222 by targeting LASS2, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0016410 N-acyltransferase activity;GO:0050291 sphingosine N-acyltransferase activity", "go_cellular_component": "GO:0098554 cytoplasmic side of endoplasmic reticulum membrane;GO:0005783 endoplasmic reticulum;GO:0031965 nuclear membrane", "go_biological_process": "GO:0006688 glycosphingolipid biosynthetic process;GO:0046513 ceramide biosynthetic process;GO:0019216 regulation of lipid metabolic process;GO:0030148 sphingolipid biosynthetic process;GO:0009611 response to wounding", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "G3V8V4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "H7C5X3-1", "uniprot_id": [ { "id": "H7C5X3_RAT", "url": "https://www.uniprot.org/uniprot/H7C5X3", "type": "external" } ], "mass": 14208.0, "length": 128, "protein_name": "NHP2-like protein 1", "gene_name": "Snu13l1", "organism": "Rat", "refseq_name": "NHP2-like protein 1", "refseq_ac": [ { "id": "XP_038956542", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038956542", "type": "external" } ], "gene_names_uniprotkb": "Snu13l1; AABR07042323.1; RGD1566078", "gene_names_refseq": "Snu13l1", "protein_names_uniprotkb": "NHP2-like protein 1", "protein_names_refseq": "NHP2-like protein 1", "tax_id": 10116, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (rno:363514)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Common component of the spliceosome and rRNA processing machinery., [UniProtKB, UniProtKB]; Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. The protein undergoes a conformational change upon RNA-binding. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) complexes that function in methylation of multiple sites on ribosomal RNAs (rRNAs) and messenger RNAs (mRNAs)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0034512 box C/D sno(s)RNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0071011 precatalytic spliceosome;GO:0031428 box C/D methylation guide snoRNP complex;GO:0046540 U4/U6 x U5 tri-snRNP complex;GO:0032040 small-subunit processome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "H7C5X3-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R3X9-1", "uniprot_id": [ { "id": "M0R3X9_RAT", "url": "https://www.uniprot.org/uniprot/M0R3X9", "type": "external" } ], "mass": 21570.0, "length": 198, "protein_name": "L antigen family member 3", "gene_name": "Ctag2l2", "organism": "Rat", "refseq_name": "EKC/KEOPS complex subunit LAGE3-like", "refseq_ac": [ { "id": "XP_006229678", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006229678", "type": "external" } ], "gene_names_uniprotkb": "Ctag2l2; LOC102552182; LOC134484035", "gene_names_refseq": "Ctag2l2", "protein_names_uniprotkb": "L antigen family member 3", "protein_names_refseq": "EKC/KEOPS complex subunit LAGE3-like", "tax_id": 10116, "disease": "Galloway-Mowat syndrome 2 (Disease Ontology:DOID:0080244)", "pathway": " (rno:102552182)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. 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Quantitative morphodynamics analysis of live oligodendrocytes showed that differentiation is driven by a stereotypical actin network-dependent 'cellular shaping' program., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0003779 actin binding;GO:0008017 microtubule binding;GO:0071933 Arp2/3 complex binding", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031252 cell leading edge;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0070358 actin polymerization-dependent cell motility;GO:0070060 'de novo' actin filament nucleation;GO:0006357 regulation of transcription by RNA polymerase II;GO:0043065 positive regulation of apoptotic process;GO:0034314 Arp2/3 complex-mediated actin nucleation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "M0R8J3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R8S7-1", "uniprot_id": [ { "id": "M0R8S7_RAT", "url": "https://www.uniprot.org/uniprot/M0R8S7", "type": "external" } ], "mass": 16153.0, "length": 146, "protein_name": "Small ribosomal subunit protein uS9", "gene_name": "LOC102548369", "organism": "Rat", "refseq_name": "small ribosomal subunit protein uS9-like", "refseq_ac": [ { "id": "XP_038950006", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_038950006", "type": "external" } ], "gene_names_uniprotkb": "LOC102548369; AABR07019341.1", "gene_names_refseq": "LOC102548369", "protein_names_uniprotkb": "Small ribosomal subunit protein uS9; 40S ribosomal protein S16", "protein_names_refseq": "small ribosomal subunit protein uS9-like", "tax_id": 10116, "disease": "", "pathway": " (rno:102548369)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R8S7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R8V9-1", "uniprot_id": [ { "id": "M0R8V9_RAT", "url": "https://www.uniprot.org/uniprot/M0R8V9", "type": "external" } ], "mass": 34911.0, "length": 311, "protein_name": "Olfactory receptor", "gene_name": "Or1j12b", "organism": "Rat", "refseq_name": "olfactory receptor Olr406", "refseq_ac": [ { "id": "NP_001000383", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000383", "type": "external" } ], "gene_names_uniprotkb": "Or1j12b", "gene_names_refseq": "Olr406; Or1j12b", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 406; olfactory receptor Olr406; olfactory receptor gene Olr406", "tax_id": 10116, "disease": "transient cerebral ischemia (Disease Ontology:DOID:224)", "pathway": " (rno:296669)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R8V9-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R8W2-1", "uniprot_id": [ { "id": "M0R8W2_RAT", "url": "https://www.uniprot.org/uniprot/M0R8W2", "type": "external" } ], "mass": 6302.0, "length": 58, "protein_name": "Keratin-associated protein 20-2-like", "gene_name": "LOC102551771", "organism": "Rat", "refseq_name": "keratin-associated protein 20-2-like", "refseq_ac": [ { "id": "XP_063127035", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063127035", "type": "external" } ], "gene_names_uniprotkb": "LOC102551771", "gene_names_refseq": "LOC102551771", "protein_names_uniprotkb": "Keratin-associated protein 20-2-like", "protein_names_refseq": "keratin-associated protein 20-2-like", "tax_id": 10116, "disease": "", "pathway": " (rno:102551771)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0005882 intermediate filament", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R8W2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R935-1", "uniprot_id": [ { "id": "M0R935_RAT", "url": "https://www.uniprot.org/uniprot/M0R935", "type": "external" } ], "mass": 41037.0, "length": 405, "protein_name": "Keratin associated protein 10-1", "gene_name": "Krtap10-1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Krtap10-1; Krtap10-10; LOC687631", "gene_names_refseq": "", "protein_names_uniprotkb": "Keratin associated protein 10-1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0045095 keratin filament", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R935-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R9B3-1", "uniprot_id": [ { "id": "M0R9B3_RAT", "url": "https://www.uniprot.org/uniprot/M0R9B3", "type": "external" } ], "mass": 76416.0, "length": 691, "protein_name": "Signal peptide peptidase-like 2C", "gene_name": "Sppl2c", "organism": "Rat", "refseq_name": "signal peptide peptidase-like 2C precursor", "refseq_ac": [ { "id": "NP_001099317", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099317", "type": "external" } ], "gene_names_uniprotkb": "Sppl2c", "gene_names_refseq": "Imp5; RGD1560562; Sppl2c", "protein_names_uniprotkb": "Signal peptide peptidase-like 2C; Intramembrane protease 5", "protein_names_refseq": "intramembrane peptidase 5; intramembrane protease 5; signal peptide peptidase-like 2C precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:287753)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "In round spermatids, acts as a scaffold protein supporting FREY1 in IZUMO1 recruitment at the endoplasmic reticulum membrane and coordination of IZUMO1 complex assembly. Stabilizes FREY1 at the endoplasmic reticulum membrane through interaction. May recruit IZUMO1 interaction partners., [UniProtKB, UniProtKB]; Sperm-specific intramembrane-cleaving aspartic protease (I-CLiP) that cleaves distinct tail-anchored proteins and SNARE proteins. In elongated spermatids, modulates intracellular Ca(2+) homeostasis by controlling PLN abundance through proteolytic cleavage. During spermatogenesis, processes SNARE proteins and impacts vesicular trafficking which supports compartmental reorganization in maturating spermatids and may play a role in formation of the acrosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0042803 protein homodimerization activity;GO:0004190 aspartic-type endopeptidase activity;GO:0042500 aspartic endopeptidase activity, intramembrane cleaving", "go_cellular_component": "GO:0098554 cytoplasmic side of endoplasmic reticulum membrane;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:0030660 Golgi-associated vesicle membrane;GO:0098553 lumenal side of endoplasmic reticulum membrane", "go_biological_process": "GO:0007283 spermatogenesis;GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization;GO:0006874 intracellular calcium ion homeostasis;GO:0050821 protein stabilization;GO:0031293 membrane protein intracellular domain proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R9B3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R9M1-1", "uniprot_id": [ { "id": "M0R9M1_RAT", "url": "https://www.uniprot.org/uniprot/M0R9M1", "type": "external" } ], "mass": 36271.0, "length": 321, "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "organism": "Rat", "refseq_name": "olfactory receptor Olr164", "refseq_ac": [ { "id": "NP_001000737", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000737", "type": "external" } ], "gene_names_uniprotkb": "Or52n1b", "gene_names_refseq": "Olr164; Or52n1b", "protein_names_uniprotkb": "Olfactory receptor family 52 subfamily N member 1B", "protein_names_refseq": "olfactory receptor 164; olfactory receptor 52N1-like; olfactory receptor Olr164; olfactory receptor gene Olr164", "tax_id": 10116, "disease": "Diamond-Blackfan anemia 8 (Disease Ontology:DOID:0111881)", "pathway": " (rno:404998)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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Feline leukemia virus subgroup C receptor-related protein 1; Heme transporter FLVCR1", "protein_names_refseq": "FLVCR heme transporter 1; feline leukemia virus subgroup C cellular receptor 1; feline leukemia virus subgroup C receptor-related protein 1-like; feline leukemia virus subgroup C receptor-related protein 1; heme transporter FLVCR1", "tax_id": 10116, "disease": "neurodevelopmental disorder with microcephaly, absent speech, and hypotonia (Disease Ontology:DOID:0051030); retinopathy sensory neuropathy syndrome (Disease Ontology:DOID:0061157); Diamond-Blackfan anemia (Disease Ontology:DOID:1339)", "pathway": " (rno:108348225)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Uniporter that mediates the transport of extracellular choline and ethanolamine into cells, thereby playing a key role in phospholipid biosynthesis. Choline and ethanolamine are the precursors of phosphatidylcholine and phosphatidylethanolamine, respectively, the two most abundant phospholipids. Transport is not coupled with proton transport and is exclusively driven by the choline (or ethanolamine) gradient across the plasma membrane. Also acts as a heme b transporter that mediates heme efflux from the cytoplasm to the extracellular compartment., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.8.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.-.-", "type": "external" } ], "go_molecular_function": "GO:0015232 heme transmembrane transporter activity;GO:0020037 heme binding;GO:0015220 choline transmembrane transporter activity;GO:0034228 ethanolamine transmembrane transporter activity;GO:0170003 heme B transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0060323 head morphogenesis;GO:0043249 erythrocyte maturation;GO:0001701 in utero embryonic development;GO:0006839 mitochondrial transport;GO:0030218 erythrocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0RB11-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0RB60-1", "uniprot_id": [ { "id": "M0RB60_RAT", "url": "https://www.uniprot.org/uniprot/M0RB60", "type": "external" } ], "mass": 119829.0, "length": 1096, "protein_name": "Leucine-rich repeats and immunoglobulin-like domains 1", "gene_name": "Lrig1", "organism": "Rat", "refseq_name": "leucine-rich repeats and immunoglobulin-like domains protein 1 precursor", "refseq_ac": [ { "id": "NP_001414730", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414730", "type": "external" } ], "gene_names_uniprotkb": "Lrig1", "gene_names_refseq": "Lrig1", "protein_names_uniprotkb": "Leucine-rich repeats and immunoglobulin-like domains 1", "protein_names_refseq": "leucine-rich repeats and immunoglobulin-like domains protein 1 precursor; leucine-rich repeats and immunoglobulin-like domains protein 1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-177929); (R-RNO-6807004)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0060384 innervation;GO:0032474 otolith morphogenesis;GO:0007605 sensory perception of sound;GO:0022405 hair cycle process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0RB60-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0RB85-1", "uniprot_id": [ { "id": "M0RB85_RAT", "url": "https://www.uniprot.org/uniprot/M0RB85", "type": "external" } ], "mass": 35764.0, "length": 319, "protein_name": "Olfactory receptor family 56 subfamily B member 2", "gene_name": "Or56b2", "organism": "Rat", "refseq_name": "olfactory receptor Olr161", "refseq_ac": [ { "id": "NP_001001000", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001000", "type": "external" } ], "gene_names_uniprotkb": "Or56b2", "gene_names_refseq": "Olr161; 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It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" } ], "go_molecular_function": "GO:0016018 cyclosporin A binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006915 apoptotic process;GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0RCZ9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0RDP5-1", "uniprot_id": [ { "id": "M0RDP5_RAT", "url": "https://www.uniprot.org/uniprot/M0RDP5", "type": "external" } ], "mass": 59256.0, "length": 530, "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "organism": "Rat", "refseq_name": "zinc finger protein 353", "refseq_ac": [ { "id": "NP_001395773", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001395773", "type": "external" } ], "gene_names_uniprotkb": "Zfp353", "gene_names_refseq": "Zfp352l; 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Dysregulation of NPGL may be a root cause of obesity. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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CACC; CaCC-1; Clca1; Clca3", "protein_names_uniprotkb": "Calcium-activated chloride channel regulator 1", "protein_names_refseq": "calcium-activated chloride channel family member 1; calcium-activated chloride channel regulator 1 precursor; calcium-activated chloride channel regulator 1; chloride channel calcium activated 3", "tax_id": 10116, "disease": "cystic fibrosis (Disease Ontology:DOID:1485); asthma (Disease Ontology:DOID:2841); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083)", "pathway": " (rno:308015); (R-RNO-2672351)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "19558866;26510883", "class_list": "", "function": "Amino acids H159 and E167 in the rbCLCA1 metalloprotease motif are important in rbCLCA1 processing for localization to the cell surface., [RefSeq, PubMed]; Dexamethasone substantially downregulates the expression of CLCA3 mRNA and Muc5ac protein in nasal mucosa in allergic rhinitis., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008237 metallopeptidase activity;GO:0046872 metal ion binding;GO:0005229 intracellularly calcium-gated chloride channel activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030141 secretory granule;GO:0005902 microvillus", "go_biological_process": "GO:0006508 proteolysis;GO:0006816 calcium ion transport;GO:0071456 cellular response to hypoxia", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2JWX9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXN8-1", "uniprot_id": [ { "id": "A0A0G2JXN8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXN8", "type": "external" } ], "mass": 104050.0, "length": 910, "protein_name": "Oxysterol-binding protein", "gene_name": "Osbpl8", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Osbpl8", "gene_names_refseq": "", "protein_names_uniprotkb": "Oxysterol-binding protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:314824); (R-RNO-1482801)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane: specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds phosphatidylserine and PI4P in a mutually exclusive manner. Binds oxysterol, 25-hydroxycholesterol and cholesterol., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015485 cholesterol binding;GO:0070273 phosphatidylinositol-4-phosphate binding;GO:0001786 phosphatidylserine binding;GO:0140343 phosphatidylserine transfer activity;GO:0160270 phosphatidylserine-phosphatidylinositol-4-phosphate exchange activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0016020 membrane;GO:0031965 nuclear membrane;GO:0032541 cortical endoplasmic reticulum", "go_biological_process": "GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0030336 negative regulation of cell migration;GO:0015914 phospholipid transport;GO:0045444 fat cell differentiation;GO:0070328 triglyceride homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JXN8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JXU3-1", "uniprot_id": [ { "id": "A0A0G2JXU3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JXU3", "type": "external" } ], "mass": 35732.0, "length": 322, "protein_name": "MAGE family member A10", "gene_name": "Magea10", "organism": "Rat", "refseq_name": "melanoma-associated antigen 10", "refseq_ac": [ { "id": "NP_001395765", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001395765", "type": "external" } ], "gene_names_uniprotkb": "Magea10", "gene_names_refseq": "Magea10; RGD1563693", "protein_names_uniprotkb": "MAGE family member A10", "protein_names_refseq": "melanoma antigen family A, 10; melanoma-associated antigen 10", "tax_id": 10116, "disease": "", "pathway": " (rno:293832)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JXU3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JYV3-1", "uniprot_id": [ { "id": "A0A0G2JYV3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JYV3", "type": "external" } ], "mass": 33313.0, "length": 298, "protein_name": "Deleted in azoospermia-like", "gene_name": "Dazl", "organism": "Rat", "refseq_name": "deleted in azoospermia-like isoform 1", "refseq_ac": [ { "id": "NP_001400853", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001400853", "type": "external" } ], "gene_names_uniprotkb": "Dazl", "gene_names_refseq": "Dazl", "protein_names_uniprotkb": "Deleted in azoospermia-like", "protein_names_refseq": "deleted in azoospermia protein 3; deleted in azoospermia-like isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:680486)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "19621088", "class_list": "", "function": "Detailed histological analysis of DAZL-deficient rat testes revealed an apparently intact spermatogonial stem cell compartment, but clear failure to produce mature haploid gametes resulting in infertility Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0008494 translation activator activity;GO:0003730 mRNA 3'-UTR binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005840 ribosome;GO:0032991 protein-containing complex", "go_biological_process": "GO:0007147 female meiosis II;GO:0045836 positive regulation of meiotic nuclear division;GO:0007283 spermatogenesis;GO:0001556 oocyte maturation;GO:0007281 germ cell development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JYV3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K0E0-1", "uniprot_id": [ { "id": "A0A0G2K0E0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K0E0", "type": "external" } ], "mass": 61367.0, "length": 546, "protein_name": "Probable ATP-dependent RNA helicase DDX56", "gene_name": "Ddx56", "organism": "Rat", "refseq_name": "probable ATP-dependent RNA helicase DDX56 isoform 2", "refseq_ac": [ { "id": "NP_001401918", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001401918", "type": "external" } ], "gene_names_uniprotkb": "Ddx56", "gene_names_refseq": "Ddx21; Ddx56; RH-II/Gu", "protein_names_uniprotkb": "Probable ATP-dependent RNA helicase DDX56; 3.6.4.13; ATP-dependent 61 kDa nucleolar RNA helicase; DEAD box protein 56", "protein_names_refseq": "DEAD (Asp-Glu-Ala-Asp) box helicase 56; DEAD (Asp-Glu-Ala-Asp) box polypeptide 56; RNA helicase II/Gu; probable ATP-dependent RNA helicase DDX56 isoform 2; probable ATP-dependent RNA helicase DDX56-like; probable ATP-dependent RNA helicase DDX56", "tax_id": 10116, "disease": "", "pathway": " (rno:289780)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Nucleolar RNA helicase that plays a role in various biological processes including innate immunity, ribosome biogenesis or nucleolus organization. Plays an essential role in maintaining nucleolar integrity in planarian stem cells. Maintains embryonic stem cells proliferation by conventional regulation of ribosome assembly and interaction with OCT4 and POU5F1 complex. Regulates antiviral innate immunity by inhibiting the virus-triggered signaling nuclear translocation of IRF3. Mechanistically, acts by disrupting the interaction between IRF3 and importin IPO5. May play a role in later stages of the processing of the pre-ribosomal particles leading to mature 60S ribosomal subunits. Has intrinsic ATPase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.9.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.9.1.1", "type": "external" }, { "id": "6.1.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.1.4.-", "url": 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Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001784 phosphotyrosine residue binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0001726 ruffle", "go_biological_process": "GO:1902531 regulation of intracellular signal transduction;GO:0050869 negative regulation of B cell activation;GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation;GO:0002820 negative regulation of adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K960-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K9C9-1", "uniprot_id": [ { "id": "A0A0G2K9C9_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K9C9", "type": "external" } ], "mass": 34879.0, "length": 315, "protein_name": "Olfactory receptor", "gene_name": "Or3a1e", "organism": "Rat", "refseq_name": "olfactory receptor Olr1512", "refseq_ac": [ { "id": "NP_001001350", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001350", "type": "external" } ], "gene_names_uniprotkb": "Or3a1e", "gene_names_refseq": "Olr1512; Or3a1e", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1512; olfactory receptor Olr1512; olfactory receptor gene Olr1512", "tax_id": 10116, "disease": "", "pathway": " (rno:287511)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K9C9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K9U0-1", "uniprot_id": [ { "id": "A0A0G2K9U0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K9U0", "type": "external" } ], "mass": 35037.0, "length": 311, "protein_name": "Coiled-coil domain containing 24", "gene_name": "Ccdc24", "organism": "Rat", "refseq_name": "coiled-coil domain-containing protein 24 isoform X4", "refseq_ac": [ { "id": "XP_006238772", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006238772", "type": "external" } ], "gene_names_uniprotkb": "Ccdc24", "gene_names_refseq": "Ccdc24; RGD1562911", "protein_names_uniprotkb": "Coiled-coil domain containing 24", "protein_names_refseq": "coiled-coil domain-containing protein 24 isoform X4", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K9U0-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2QC22-1", "uniprot_id": [ { "id": "A0A0G2QC22_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2QC22", "type": "external" } ], "mass": 24239.0, "length": 225, "protein_name": "PAXX, non-homologous end joining factor", "gene_name": "Paxx", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Paxx; RGD1306215", "gene_names_refseq": "", "protein_names_uniprotkb": "PAXX, non-homologous end joining factor", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0070182 DNA polymerase binding", "go_cellular_component": "GO:0070419 nonhomologous end joining complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0035861 site of double-strand break;GO:0043564 Ku70:Ku80 complex", "go_biological_process": "GO:0006974 DNA damage response;GO:0006303 double-strand break repair via nonhomologous end joining", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2QC22-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B0BMV4-1", "uniprot_id": [ { "id": "B0BMV4_RAT", "url": "https://www.uniprot.org/uniprot/B0BMV4", "type": "external" } ], "mass": 32049.0, "length": 293, "protein_name": "Protein YIF1", "gene_name": "Yif1a", "organism": "Rat", "refseq_name": "protein YIF1A", "refseq_ac": [ { "id": "NP_742014", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_742014", "type": "external" } ], "gene_names_uniprotkb": "Yif1a", "gene_names_refseq": "Yif1a; Yif1p; Yif1", "protein_names_uniprotkb": "Protein YIF1", "protein_names_refseq": "Yip1p-interacting factor; liver protein; protein YIF1A", "tax_id": 10116, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (rno:171441)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23736259", "class_list": "", "function": "Has a role in transport between endoplasmic reticulum and Golgi., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; YIF1A interacts with VAPB via its transmembrane regions, recycles between the ER and Golgi and is mainly localized to the ER-Golgi intermediate compartments in hippocampal neurons., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0030134 COPII-coated ER to Golgi transport vesicle;GO:0005789 endoplasmic reticulum membrane;GO:0005793 endoplasmic reticulum-Golgi intermediate compartment", "go_biological_process": "GO:0015031 protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "B0BMV4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B0BN16-1", "uniprot_id": [ { "id": "B0BN16_RAT", "url": "https://www.uniprot.org/uniprot/B0BN16", "type": "external" } ], "mass": 28681.0, "length": 270, "protein_name": "Insulin-like growth factor-binding protein-like 1", "gene_name": "Igfbpl1", "organism": "Rat", "refseq_name": "insulin-like growth factor-binding protein-like 1 precursor", "refseq_ac": [ { "id": "NP_001102442", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102442", "type": "external" } ], "gene_names_uniprotkb": "Igfbpl1", "gene_names_refseq": "Igfbpl1", "protein_names_uniprotkb": "Insulin-like growth factor-binding protein-like 1; IGFBP-related protein 10; Insulin-like growth factor-binding-related protein 4", "protein_names_refseq": "insulin-like growth factor-binding protein-like 1 precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:366366)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005520 insulin-like growth factor binding;GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0071228 cellular response to tumor cell;GO:0001558 regulation of cell growth;GO:0009966 regulation of signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B0BN16-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B0BN63-1", "uniprot_id": [ { "id": "B0BN63_RAT", "url": "https://www.uniprot.org/uniprot/B0BN63", "type": "external" } ], "mass": 38104.0, "length": 338, "protein_name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "gene_name": "Ahsa1", "organism": "Rat", "refseq_name": "activator of 90 kDa heat shock protein ATPase homolog 1", "refseq_ac": [ { "id": "NP_001108506", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108506", "type": "external" } ], "gene_names_uniprotkb": "Ahsa1; LOC681996", "gene_names_refseq": "Ahsa1", "protein_names_uniprotkb": "Activator of 90 kDa heat shock protein ATPase homolog 1", "protein_names_refseq": "AHA1, activator of heat shock 90kDa protein ATPase homolog 1; activator of 90 kDa heat shock protein ATPase homolog 1", "tax_id": 10116, "disease": "", "pathway": " (rno:681996)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins. Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0051087 protein-folding chaperone binding;GO:0001671 ATPase activator activity;GO:0051879 Hsp90 protein binding;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005829 cytosol", "go_biological_process": "GO:0006457 protein folding;GO:0032781 positive regulation of ATP-dependent activity;GO:0036506 maintenance of unfolded protein", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B0BN63-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B0BN98-1", "uniprot_id": [ { "id": "B0BN98_RAT", "url": "https://www.uniprot.org/uniprot/B0BN98", "type": "external" } ], "mass": 14933.0, "length": 126, "protein_name": "Protein LLP homolog", "gene_name": "Llph", "organism": "Rat", "refseq_name": "protein LLP homolog", "refseq_ac": [ { "id": "NP_001127936", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001127936", "type": "external" } ], "gene_names_uniprotkb": "Llph; Llph-ps1", "gene_names_refseq": "Llph; RGD1308261", "protein_names_uniprotkb": "Protein LLP homolog; Protein LAPS18-like", "protein_names_refseq": "LLP homolog, long-term synaptic facilitation (Aplysia); protein LLP homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:299818)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001099 basal RNA polymerase II transcription machinery binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005694 chromosome", "go_biological_process": "GO:0060999 positive regulation of dendritic spine development;GO:0097484 dendrite extension", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B0BN98-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B0BNF9-1", "uniprot_id": [ { "id": "HAOX1_RAT", "url": "https://www.uniprot.org/uniprot/B0BNF9", "type": "external" } ], "mass": 40968.0, "length": 370, "protein_name": "2-Hydroxyacid oxidase 1", "gene_name": "Hao1", "organism": "Rat", "refseq_name": "2-Hydroxyacid oxidase 1", "refseq_ac": [ { "id": "NP_001101250", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101250", "type": "external" } ], "gene_names_uniprotkb": "Hao1", "gene_names_refseq": "GOX; Gox1; HAOX1; Hao1; XDH1", "protein_names_uniprotkb": "2-Hydroxyacid oxidase 1; 1.1.3.15; 1.2.3.5; GOX; Glycolate oxidase; Glyoxylate oxidase; HAOX1", "protein_names_refseq": "2-Hydroxyacid oxidase 1; glycolate oxidase; glyoxylate oxidase; hydroxyacid oxidase (glycolate oxidase) 1; hydroxyacid oxidase 1, liver", "tax_id": 10116, "disease": "", "pathway": " (rno:311446); (R-RNO-389661); (R-RNO-9033241)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "10777549;14578854;16396499;19758989;22673903", "class_list": "", "function": "Broad substrate specificity (S)-2-hydroxy-acid oxidase that preferentially oxidizes glycolate. The glyoxylate produced by the oxidation of glycolate can then be utilized by alanine-glyoxylate aminotransferase for the peroxisomal synthesis of glycine; this pathway appears to be an important step for the detoxification of glyoxylate which, if allowed to accumulate, may be metabolized to oxalate with formation of kidney stones. Can also catalyze the oxidation of glyoxylate, and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydroxyoctanoate. Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCIP), but O2 is believed to be the physiological electron acceptor, leading to the production of H2O2., [UniProtKB, UniProtKB]; Down-regulation of Hao1 during oxidative stress may provide mechanism to prevent excessive H2O2 formation in liver peroxisomes. May be prototype of response to oxidative injury involving down-regulation of reactive oxygen species-producing enzymes., [RefSeq, PubMed]; The turnover of the enzyme and the rate constant for flavin were pH-independent, suggesting the involvement of an unprotonated group acting as a base in the chemical step of glycolate oxidation., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.3.15", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.3.15", "type": "external" }, { "id": "1.2.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.3.5", "type": "external" }, { "id": "3.4.21.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "1.4.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.1", "type": "external" }, { "id": "1.4.3.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.3", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.-", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "1.3.3.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.3.6", "type": "external" }, { "id": "2.6.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.51", "type": "external" }, { "id": "2.6.1.44", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.44", "type": "external" }, { "id": "2.3.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.137", "type": "external" }, { "id": "2.3.1.176", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.176", "type": "external" }, { "id": "2.3.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.16", "type": "external" }, { "id": "2.3.1.155", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.155", "type": "external" }, { "id": "2.3.2.36", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.36", "type": "external" }, { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" }, { "id": "3.4.24.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.56", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "5.1.99.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.99.4", "type": "external" }, { "id": "4.1.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.3.4", "type": "external" }, { "id": "6.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.3", "type": "external" }, { "id": "6.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.-", "type": "external" }, { "id": "6.2.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.7", "type": "external" }, { "id": "6.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.24", "type": "external" }, { "id": "6.2.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.15", "type": "external" }, { "id": "1.14.13.39", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.39", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "5.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.8", "type": "external" }, { "id": "5.3.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.21", "type": "external" }, { "id": "3.1.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.27", "type": "external" }, { "id": "2.3.1.65", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.65", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.1.77", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.77", "type": "external" }, { "id": "2.3.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.7", "type": "external" }, { "id": "4.1.2.63", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.63", "type": "external" }, { "id": "3.1.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.1", "type": "external" }, { "id": "3.1.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.11", "type": "external" }, { "id": "3.1.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.3", "type": "external" }, { "id": "3.1.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.5", "type": "external" }, { "id": "1.1.1.300", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.300", "type": "external" }, { "id": "1.1.1.184", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.184", "type": "external" }, { "id": "4.1.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.9", "type": "external" }, { "id": "2.3.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.42", "type": "external" }, { "id": "1.3.1.38", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.38", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "1.3.1.124", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.124", "type": "external" } ], "go_molecular_function": "GO:0010181 FMN binding;GO:0003973 (S)-2-hydroxy-acid oxidase activity;GO:0047969 glyoxylate oxidase activity", "go_cellular_component": "GO:0005777 peroxisome;GO:0005782 peroxisomal matrix", "go_biological_process": "GO:0006545 glycine biosynthetic process;GO:0006979 response to oxidative stress;GO:0001561 fatty acid alpha-oxidation;GO:0046296 glycolate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "B0BNF9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B1H261-1", "uniprot_id": [ { "id": "B1H261_RAT", "url": "https://www.uniprot.org/uniprot/B1H261", "type": "external" } ], "mass": 58986.0, "length": 567, "protein_name": "Peroxisomal leader peptide-processing protease", "gene_name": "Tysnd1", "organism": "Rat", "refseq_name": "peroxisomal leader peptide-processing protease", "refseq_ac": [ { "id": "NP_001102402", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102402", "type": "external" } ], "gene_names_uniprotkb": "Tysnd1", "gene_names_refseq": "Tysnd1", "protein_names_uniprotkb": "Peroxisomal leader peptide-processing protease; 3.4.21.-", "protein_names_refseq": "peroxisomal leader peptide-processing protease; trypsin domain containing 1", "tax_id": 10116, "disease": "", "pathway": " (rno:365571); (R-RNO-9033241); (R-RNO-9033500)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "17255948", "class_list": "", "function": "Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids., [UniProtKB, UniProtKB, UniProtKB]; Tysnd1-mediated processing of the peroxisomal enzymes promotes their assembly into a supramolecular complex to enhance the rate of beta-oxidation., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.3.15", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.3.15", "type": "external" }, { "id": "1.2.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.3.5", "type": "external" }, { "id": "3.4.21.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "1.4.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.1", "type": "external" }, { "id": "1.4.3.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.3", "type": "external" }, { "id": "3.1.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2", "type": "external" }, { "id": "3.1.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.-", "type": "external" }, { "id": "1.11.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.6", "type": "external" }, { "id": "1.3.3.6", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.3.6", "type": "external" }, { "id": "2.6.1.51", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.51", "type": "external" }, { "id": "2.6.1.44", "url": "https://www.rhea-db.org/rhea/?query=ec:2.6.1.44", "type": "external" }, { "id": "2.3.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.137", "type": "external" }, { "id": "2.3.1.176", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.176", "type": "external" }, { "id": "2.3.1.16", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.16", "type": "external" }, { "id": "2.3.1.155", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.155", "type": "external" }, { "id": "2.3.2.36", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.36", "type": "external" }, { "id": "2.5.1.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18", "type": "external" }, { "id": "3.4.24.56", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.56", "type": "external" }, { "id": "1.1.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.42", "type": "external" }, { "id": "5.1.99.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.99.4", "type": "external" }, { "id": "4.1.3.4", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.3.4", "type": "external" }, { "id": "6.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.3", "type": "external" }, { "id": "6.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.-", "type": "external" }, { "id": "6.2.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.7", "type": "external" }, { "id": "6.2.1.24", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.24", "type": "external" }, { "id": "6.2.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.15", "type": "external" }, { "id": "1.14.13.39", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.13.39", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "5.3.3.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.8", "type": "external" }, { "id": "5.3.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.21", "type": "external" }, { "id": "3.1.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.27", "type": "external" }, { "id": "2.3.1.65", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.65", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.1.77", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.77", "type": "external" }, { "id": "2.3.1.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.7", "type": "external" }, { "id": "4.1.2.63", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.2.63", "type": "external" }, { "id": "3.1.2.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.1", "type": "external" }, { "id": "3.1.2.11", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.11", "type": "external" }, { "id": "3.1.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.3", "type": "external" }, { "id": "3.1.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.5", "type": "external" }, { "id": "1.1.1.300", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.300", "type": "external" }, { "id": "1.1.1.184", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.184", "type": "external" }, { "id": "4.1.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.9", "type": "external" }, { "id": "2.3.1.42", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.42", "type": "external" }, { "id": "1.3.1.38", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.38", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "1.3.1.124", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.124", "type": "external" } ], "go_molecular_function": "GO:0002020 protease binding;GO:0004252 serine-type endopeptidase activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005777 peroxisome;GO:0005782 peroxisomal matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0016485 protein processing;GO:0031998 regulation of fatty acid beta-oxidation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "B1H261-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B1WBS6-1", "uniprot_id": [ { "id": "B1WBS6_RAT", "url": "https://www.uniprot.org/uniprot/B1WBS6", "type": "external" } ], "mass": 73262.0, "length": 646, "protein_name": "beta-galactosidase", "gene_name": "Glb1l", "organism": "Rat", "refseq_name": "beta-galactosidase-1-like protein precursor", "refseq_ac": [ { "id": "NP_001121001", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121001", "type": "external" } ], "gene_names_uniprotkb": "Glb1l", "gene_names_refseq": "Glb1l", "protein_names_uniprotkb": "beta-galactosidase; 3.2.1.23", "protein_names_refseq": "beta-galactosidase-1-like protein precursor; beta-galactosidase-1-like protein", "tax_id": 10116, "disease": "", "pathway": " (rno:301525); (R-RNO-2022857); (R-RNO-2024101); (R-RNO-9840310)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.23", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.23", "type": "external" } ], "go_molecular_function": "GO:0004565 beta-galactosidase activity", "go_cellular_component": "GO:0005773 vacuole", "go_biological_process": "GO:0019388 galactose catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B1WBS6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B1WBV3-1", "uniprot_id": [ { "id": "B1WBV3_RAT", "url": "https://www.uniprot.org/uniprot/B1WBV3", "type": "external" } ], "mass": 40636.0, "length": 369, "protein_name": "Glucose-fructose oxidoreductase domain-containing protein 2", "gene_name": "Gfod2", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Gfod2", "gene_names_refseq": "", "protein_names_uniprotkb": "Glucose-fructose oxidoreductase domain-containing protein 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:307801)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Promotes matrix assembly., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016491 oxidoreductase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0031012 extracellular matrix", "go_biological_process": "GO:0030198 extracellular matrix organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B1WBV3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B1WBZ9-1", "uniprot_id": [ { "id": "B1WBZ9_RAT", "url": "https://www.uniprot.org/uniprot/B1WBZ9", "type": "external" } ], "mass": 34022.0, "length": 299, "protein_name": "Katanin regulatory subunit B1 like 1", "gene_name": "Katnbl1", "organism": "Rat", "refseq_name": "KATNB1-like protein 1", "refseq_ac": [ { "id": "NP_001103115", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103115", "type": "external" } ], "gene_names_uniprotkb": "Katnbl1", "gene_names_refseq": "Katnbl1", "protein_names_uniprotkb": "Katanin regulatory subunit B1 like 1", "protein_names_refseq": "KATNB1-like protein 1; katanin p80 subunit B-like 1", "tax_id": 10116, "disease": "", "pathway": " (rno:691543)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, 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of cytoskeleton organization;GO:0031122 cytoplasmic microtubule organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B1WBZ9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B1WC24-1", "uniprot_id": [ { "id": "B1WC24_RAT", "url": "https://www.uniprot.org/uniprot/B1WC24", "type": "external" } ], "mass": 29294.0, "length": 261, "protein_name": "protein-serine/threonine phosphatase", "gene_name": "Ctdsp1", "organism": "Rat", "refseq_name": "carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1", "refseq_ac": [ { "id": "NP_001121551", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121551", "type": "external" } ], "gene_names_uniprotkb": "Ctdsp1", "gene_names_refseq": "Ctdsp1", "protein_names_uniprotkb": "protein-serine/threonine phosphatase; 3.1.3.16", "protein_names_refseq": "CTD (carboxy-terminal domain, RNA polymerase 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Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, 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}, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "3.1.3.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.74", "type": "external" } ], "go_molecular_function": "GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045665 negative regulation of neuron differentiation;GO:0001933 negative regulation of protein phosphorylation;GO:0006470 protein dephosphorylation;GO:2000134 negative regulation of G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B1WC24-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B1WC66-1", "uniprot_id": [ { "id": "B1WC66_RAT", "url": "https://www.uniprot.org/uniprot/B1WC66", "type": "external" } ], "mass": 52458.0, "length": 461, "protein_name": "5'-nucleotidase domain-containing protein 1", "gene_name": "Nt5dc1", "organism": "Rat", "refseq_name": "5'-nucleotidase domain-containing protein 1", "refseq_ac": [ { "id": "NP_001099863", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099863", "type": "external" } ], "gene_names_uniprotkb": "Nt5dc1", "gene_names_refseq": "Nt5c2l1; Nt5dc1", "protein_names_uniprotkb": "5'-nucleotidase domain-containing protein 1", "protein_names_refseq": "5'-nucleotidase domain-containing protein 1-like; 5'-nucleotidase domain-containing protein 1; 5'-nucleotidase, cytosolic II-like 1", "tax_id": 10116, "disease": "", "pathway": " (rno:294456)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F7EPM6", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0008253 5'-nucleotidase activity;GO:0016787 hydrolase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B1WC66-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B2GV70-1", "uniprot_id": [ { "id": "B2GV70_RAT", "url": "https://www.uniprot.org/uniprot/B2GV70", "type": "external" } ], "mass": 8832.0, "length": 80, "protein_name": "Cortexin 3", "gene_name": "Ctxn3", "organism": "Rat", "refseq_name": "cortexin-3", "refseq_ac": [ { "id": "NP_001128168", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128168", "type": "external" } ], "gene_names_uniprotkb": "Ctxn3", "gene_names_refseq": "Ctxn3", "protein_names_uniprotkb": "Cortexin 3", "protein_names_refseq": "cortexin-3", "tax_id": 10116, "disease": "", "pathway": " (rno:100188934)", 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nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005764 lysosome", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0010507 negative regulation of autophagy;GO:0009267 cellular response to starvation;GO:1990253 cellular response to leucine starvation;GO:0071233 cellular response to L-leucine", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "B2RZ38-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B2RZ77-1", "uniprot_id": [ { "id": "B2RZ77_RAT", "url": "https://www.uniprot.org/uniprot/B2RZ77", "type": "external" } ], "mass": 24203.0, "length": 202, "protein_name": "Dermatopontin", "gene_name": "Dpt", "organism": "Rat", "refseq_name": "dermatopontin isoform 1 precursor", "refseq_ac": [ { "id": "NP_001388295", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388295", "type": "external" } ], 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3ZYB9", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z7Y3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z830-1", "uniprot_id": [ { "id": "D3Z830_RAT", "url": "https://www.uniprot.org/uniprot/D3Z830", "type": "external" } ], "mass": 69801.0, "length": 619, "protein_name": "Monooxygenase, DBH-like 2", "gene_name": "Moxd2", "organism": "Rat", "refseq_name": "monooxygenase, DBH-like 2 precursor", "refseq_ac": [ { "id": "NP_001102699", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102699", "type": "external" } ], "gene_names_uniprotkb": "Moxd2", "gene_names_refseq": "Moxd2; RGD1564286", "protein_names_uniprotkb": "Monooxygenase, DBH-like 2", "protein_names_refseq": "monooxygenase, DBH-like 2 precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:500092)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005507 copper ion binding;GO:0004500 dopamine beta-monooxygenase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0030667 secretory granule membrane", "go_biological_process": "GO:0042420 dopamine catabolic process;GO:0006589 octopamine biosynthetic process;GO:0042421 norepinephrine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z830-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z8G7-1", "uniprot_id": [ { "id": "D3Z8G7_RAT", "url": "https://www.uniprot.org/uniprot/D3Z8G7", "type": "external" } ], "mass": 100219.0, "length": 911, "protein_name": "Tight junction protein 3", "gene_name": "Tjp3", "organism": "Rat", "refseq_name": "tight junction protein ZO-3 isoform 1", "refseq_ac": [ { "id": "NP_001424894", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001424894", "type": "external" } ], "gene_names_uniprotkb": "Tjp3", "gene_names_refseq": "Tjp3", "protein_names_uniprotkb": "Tight junction protein 3", "protein_names_refseq": "tight junction protein ZO-3 isoform 1; tight junction protein ZO-3", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "16641100;22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005911 cell-cell junction", "go_biological_process": "GO:2000045 regulation of G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3Z8G7-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z922-1", "uniprot_id": [ { "id": "D3Z922_RAT", "url": "https://www.uniprot.org/uniprot/D3Z922", "type": "external" } ], "mass": 15451.0, "length": 136, "protein_name": "V-set pre-B cell surrogate light chain 1B", "gene_name": "Vpreb1a; Vpreb1b", "organism": "Rat", "refseq_name": "immunoglobulin iota chain precursor", "refseq_ac": [ { "id": "NP_001102315", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102315", "type": "external" } ], "gene_names_uniprotkb": "Vpreb1a; Vpreb1b; Vpreb1a; Vpreb1b", "gene_names_refseq": "Vpreb1a; Vpreb1", "protein_names_uniprotkb": "V-set pre-B cell surrogate light chain 1B", "protein_names_refseq": "Immunoglobulin lambda Vpreb1 chain; V-set pre-B cell surrogate light chain 1; immunoglobulin iota chain precursor; immunoglobulin iota chain; immunoglobulin omega chain-like; pre-B lymphocyte 1; pre-B lymphocyte gene 1", "tax_id": 10116, "disease": "", "pathway": " (rno:303782); (rno:363830)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0019814 immunoglobulin complex;GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006955 immune response;GO:0001782 B cell homeostasis;GO:0042100 B cell proliferation;GO:0000902 cell morphogenesis;GO:0030097 hemopoiesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z922-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3Z980-1", "uniprot_id": [ { "id": "D3Z980_RAT", "url": "https://www.uniprot.org/uniprot/D3Z980", "type": "external" } ], "mass": 87051.0, "length": 767, "protein_name": "Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2", "gene_name": "Cmtr2", "organism": "Rat", "refseq_name": "cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2", "refseq_ac": [ { "id": "NP_001099656", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099656", "type": "external" } ], "gene_names_uniprotkb": "Cmtr2; Ftsjd1", "gene_names_refseq": "Cmtr2; Ftsjd1; RGD1309394", "protein_names_uniprotkb": "Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2; 2.1.1.296; Cap methyltransferase 2; Cap2 2'O-ribose methyltransferase 2; FtsJ methyltransferase domain-containing protein 1", "protein_names_refseq": "FtsJ methyltransferase domain containing 1; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2; ftsJ methyltransferase domain-containing protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:292016)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N(7) methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.296", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.296", "type": "external" } ], "go_molecular_function": "GO:0004483 methyltransferase cap1 activity;GO:0120550 methyltransferase cap2 activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0032259 methylation;GO:0006370 7-methylguanosine mRNA capping", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3Z980-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZA29-1", "uniprot_id": [ { "id": "D3ZA29_RAT", "url": "https://www.uniprot.org/uniprot/D3ZA29", "type": "external" } ], "mass": 35083.0, "length": 310, "protein_name": "Olfactory receptor", "gene_name": "Or5w12", "organism": "Rat", "refseq_name": "olfactory receptor Olr578", "refseq_ac": [ { "id": "NP_001000568", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000568", "type": "external" } ], "gene_names_uniprotkb": "Or5w12", "gene_names_refseq": "Olr578; Or5w12", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 578; olfactory receptor Olr578; olfactory receptor gene Olr578", "tax_id": 10116, "disease": "", "pathway": " (rno:366109)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZA29-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZA46-1", "uniprot_id": [ { "id": "D3ZA46_RAT", "url": "https://www.uniprot.org/uniprot/D3ZA46", "type": "external" } ], "mass": 107197.0, "length": 969, "protein_name": "Gem-interacting protein", "gene_name": "Gmip", "organism": "Rat", "refseq_name": "GEM-interacting protein", "refseq_ac": [ { "id": "NP_001100778", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100778", "type": "external" } ], "gene_names_uniprotkb": "Gmip", "gene_names_refseq": "Gmip; RGD1565577", "protein_names_uniprotkb": "Gem-interacting protein", "protein_names_refseq": "GEM-interacting protein", "tax_id": 10116, "disease": "", "pathway": " (rno:306357); (R-RNO-8980692); (R-RNO-9013148); (R-RNO-9013149)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "22673903;29393594", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0051058 negative regulation of small GTPase mediated signal transduction;GO:0007264 small GTPase-mediated signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZA46-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZA93-1", "uniprot_id": [ { "id": "D3ZA93_RAT", "url": "https://www.uniprot.org/uniprot/D3ZA93", "type": "external" } ], "mass": 13623.0, "length": 126, "protein_name": "Acyl-coenzyme A thioesterase 13", "gene_name": "Acot13", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Acot13", "gene_names_refseq": "", "protein_names_uniprotkb": "Acyl-coenzyme A thioesterase 13; 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Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Can also hydrolyze 3-hydroxyphenylacetyl-CoA and 3,4-dihydroxyphenylacetyl-CoA (in vitro). 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Or7c19; ratchr19-23198893-23197955_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1666; olfactory receptor Olr1666; olfactory receptor gene Olr1666", "tax_id": 10116, "disease": "", "pathway": " (rno:291929)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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RGD1310774", "protein_names_uniprotkb": "GTP binding elongation factor GUF1", "protein_names_refseq": "GTP-binding protein GUF1 homolog; GUF1 GTPase homolog; GUF1 homolog, GTPase; translation factor GUF1, mitochondrial", "tax_id": 10116, "disease": "West syndrome (Disease Ontology:DOID:0050562); developmental and epileptic encephalopathy 40 (Disease Ontology:DOID:0080427)", "pathway": " (rno:305317)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "36905457", "class_list": "", "function": "Guf1 overexpression improves pancreatic beta cell functions in type 2 diabetes mellitus rats with Roux-en-Y gastric bypass (RYGB) surgery., [RefSeq, PubMed]; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.1", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0097177 mitochondrial ribosome binding;GO:0043022 ribosome binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006412 translation;GO:0045727 positive regulation of translation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZHF8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZHH8-1", "uniprot_id": [ { "id": "D3ZHH8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZHH8", "type": "external" } ], "mass": 51175.0, "length": 504, "protein_name": "Serum response factor", "gene_name": "Srf", "organism": "Rat", "refseq_name": "serum response factor", "refseq_ac": [ { "id": "NP_001102772", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102772", "type": "external" } ], "gene_names_uniprotkb": "Srf", "gene_names_refseq": "RGD1559787; Srf", "protein_names_uniprotkb": "Serum response factor", "protein_names_refseq": "serum response factor (c-fos serum response element-binding transcription factor); serum response factor", "tax_id": 10116, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); hypertension (Disease Ontology:DOID:10763); dilated cardiomyopathy (Disease Ontology:DOID:12930); lymphangioleiomyomatosis (Disease Ontology:DOID:3319); congestive heart failure (Disease Ontology:DOID:6000); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (rno:501099); (R-RNO-5663220); (R-RNO-9031628)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "22673903;31774735;33406503;36527644;36801840;38421133", "class_list": "", "function": "Acidosis-Induced Regulation of Egr1 and Ccn1 In Vitro and in Experimental Tumours In Vivo., [RefSeq, PubMed]; Crucial role of serum response factor in renal tubular epithelial cell epithelial-mesenchymal transition in hyperuricemic nephropathy., [RefSeq, PubMed]; SRF and SRF Cofactor mRNA Expression Is Differentially Regulated by BDNF Stimulation in Cortical Neurons., [RefSeq, PubMed]; SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics. Required for cardiac differentiation and maturation., [UniProtKB, UniProtKB]; Serum response factor promoting axonal regeneration by activating the Ras-Raf-Cofilin signaling pathway after the spinal cord injury., [RefSeq, PubMed]; Serum response factor, a novel early diagnostic biomarker of acute kidney injury., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0010736 serum response element binding;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0003700 DNA-binding transcription factor activity;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0030878 thyroid gland development;GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0046016 positive regulation of transcription by glucose;GO:0060379 cardiac muscle cell myoblast differentiation;GO:0060534 trachea cartilage development", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "D3ZHH8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZI89-1", "uniprot_id": [ { "id": "D3ZI89_RAT", "url": "https://www.uniprot.org/uniprot/D3ZI89", "type": "external" } ], "mass": 53026.0, "length": 488, "protein_name": "Solute carrier family 7 (cationic amino acid transporter, y+ system), member 15", "gene_name": "Slc7a15", "organism": "Rat", "refseq_name": "solute carrier family 7 (cationic amino acid transporter, y+ system), member 15", "refseq_ac": [ { "id": "NP_001100184", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100184", "type": "external" } ], "gene_names_uniprotkb": "Slc7a15", "gene_names_refseq": "RGD1560726; Slc7a15", "protein_names_uniprotkb": "Solute carrier family 7 (cationic amino acid transporter, y+ system), member 15", "protein_names_refseq": "solute carrier family 7 (cationic amino acid transporter, y+ system), member 15", "tax_id": 10116, "disease": "", "pathway": " (rno:298873)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015179 L-amino acid transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:0003333 amino acid transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZI89-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZIE7-1", "uniprot_id": [ { "id": "D3ZIE7_RAT", "url": "https://www.uniprot.org/uniprot/D3ZIE7", "type": "external" } ], "mass": 34795.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or13j1", "organism": "Rat", "refseq_name": "olfactory receptor Olr834", "refseq_ac": [ { "id": "NP_001000407", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000407", "type": "external" } ], "gene_names_uniprotkb": "Or13j1", "gene_names_refseq": "Olr834; Or13j1", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 834; olfactory receptor Olr834; olfactory receptor gene Olr834", "tax_id": 10116, "disease": "", "pathway": " (rno:298396)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZIE7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZIJ5-1", "uniprot_id": [ { "id": "D3ZIJ5_RAT", "url": "https://www.uniprot.org/uniprot/D3ZIJ5", "type": "external" } ], "mass": 10091.0, "length": 92, "protein_name": "Dolichol-phosphate mannosyltransferase subunit 3", "gene_name": "Dpm3", "organism": "Rat", "refseq_name": "dolichol-phosphate mannosyltransferase subunit 3", "refseq_ac": [ { "id": "NP_001102801", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102801", "type": "external" } ], "gene_names_uniprotkb": "Dpm3; Dpm3-ps1; LOC100910177", "gene_names_refseq": "Dpm3; RGD1561807", "protein_names_uniprotkb": "Dolichol-phosphate mannosyltransferase subunit 3", "protein_names_refseq": "dolichol-phosphate mannosyltransferase subunit 3; dolichyl-phosphate mannosyltransferase polypeptide 3", "tax_id": 10116, "disease": "congenital disorder of glycosylation type I (Disease Ontology:DOID:0050570); muscular dystrophy-dystroglycanopathy type B15 (Disease Ontology:DOID:0112376)", "pathway": " (rno:502017); (R-RNO-162699)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008047 enzyme activator activity", "go_cellular_component": "GO:0033185 dolichol-phosphate-mannose synthase complex;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0043048 dolichyl monophosphate biosynthetic process;GO:0180047 dolichol phosphate mannose biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZIJ5-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZIN8-1", "uniprot_id": [ { "id": "D3ZIN8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZIN8", "type": "external" } ], "mass": 31892.0, "length": 287, "protein_name": "Programmed cell death protein 1", "gene_name": "Pdcd1", "organism": "Rat", "refseq_name": "programmed cell death protein 1", "refseq_ac": [ { "id": "NP_001100397", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100397", "type": "external" } ], "gene_names_uniprotkb": "Pdcd1", "gene_names_refseq": "Pdcd1", "protein_names_uniprotkb": "Programmed cell death protein 1", "protein_names_refseq": "programmed cell death protein 1-like; programmed cell death protein 1", "tax_id": 10116, "disease": "infantile onset multisystem autoimmune disease 4 (Disease Ontology:DOID:0061163); Cryptococcal meningitis (Disease Ontology:DOID:0080159); lupus nephritis (Disease Ontology:DOID:0080162); stomach cancer (Disease Ontology:DOID:10534); pre-eclampsia (Disease Ontology:DOID:10591); anogenital venereal wart (Disease Ontology:DOID:11168); hepatitis A (Disease Ontology:DOID:12549); respiratory syncytial virus infectious disease (Disease Ontology:DOID:1273); dilated cardiomyopathy (Disease Ontology:DOID:12930); toxic shock syndrome (Disease Ontology:DOID:14115); hepatitis C (Disease Ontology:DOID:1883); hepatitis B (Disease Ontology:DOID:2043); autoimmune hepatitis (Disease Ontology:DOID:2048); hepatitis (Disease Ontology:DOID:2237); pulmonary tuberculosis (Disease Ontology:DOID:2957); lung adenocarcinoma (Disease Ontology:DOID:3910); tuberculosis (Disease Ontology:DOID:399); renal cell carcinoma (Disease Ontology:DOID:4450); anti-basement membrane glomerulonephritis (Disease Ontology:DOID:4780); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); hepatocellular carcinoma (Disease Ontology:DOID:684); periodontitis (Disease Ontology:DOID:824); cervix uteri carcinoma in situ (Disease Ontology:DOID:8991); systemic lupus erythematosus (Disease Ontology:DOID:9074)", "pathway": " (rno:301626); (R-RNO-389948); (R-RNO-9931295)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "34170847;34847253", "class_list": "", "function": "A newly intervention strategy in preeclampsia: Targeting PD-1/Tim-3 signaling pathways to modulate the polarization of decidual macrophages., [RefSeq, PubMed]; Programmed death-1 mediates venous neointimal hyperplasia in humans and rats., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 24, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process;GO:0050776 regulation of immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZIN8-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZIT4-1", "uniprot_id": [ { "id": "D3ZIT4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZIT4", "type": "external" } ], "mass": 70249.0, "length": 632, "protein_name": "Anaphase-promoting complex subunit 7", "gene_name": "Anapc7", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Anapc7", "gene_names_refseq": "", "protein_names_uniprotkb": "Anaphase-promoting complex subunit 7; Cyclosome subunit 7", "protein_names_refseq": "", "tax_id": 10116, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888)", "pathway": " (rno:304490); (R-RNO-141430); (R-RNO-174048); (R-RNO-174084); (R-RNO-174154); (R-RNO-174178); (R-RNO-174184); (R-RNO-176407); (R-RNO-176408); (R-RNO-176412); (R-RNO-179409); (R-RNO-2467813); (R-RNO-2559582); (R-RNO-68867); (R-RNO-69017); (R-RNO-983168)", "pathway_count": 16, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins. APC7 is not required for the assembly of the APC/C complex, but has an enzyme-substrate adapter activity mediating the processive ubiquitination of specific substrates. 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"organism": "Rat", "refseq_name": "olfactomedin-4 precursor", "refseq_ac": [ { "id": "NP_001099522", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099522", "type": "external" } ], "gene_names_uniprotkb": "Olfm4", "gene_names_refseq": "Olfm4", "protein_names_uniprotkb": "Olfactomedin 4", "protein_names_refseq": "olfactomedin-4 precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:290409); (R-RNO-6798695)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "39278846", "class_list": "", "function": "Knockdown of OLFM4 protects cardiomyocytes from sepsis by inhibiting apoptosis and inflammatory responses. 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Sla2", "protein_names_uniprotkb": "Src-like-adapter 2; Src-like adapter protein 2", "protein_names_refseq": "src-like-adapter 2", "tax_id": 10116, "disease": "", "pathway": " (rno:499931)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle;GO:0005770 late endosome;GO:0005737 cytoplasm", "go_biological_process": "GO:0050849 negative regulation of calcium-mediated signaling;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0042110 T cell activation;GO:0050860 negative regulation of T cell receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZMV1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZN69-1", "uniprot_id": [ { "id": "D3ZN69_RAT", "url": "https://www.uniprot.org/uniprot/D3ZN69", "type": "external" } ], "mass": 86546.0, "length": 754, "protein_name": "Serine/threonine-protein phosphatase with EF-hands", "gene_name": "Ppef2", "organism": "Rat", "refseq_name": "serine/threonine-protein phosphatase with EF-hands 2", "refseq_ac": [ { "id": "NP_001100680", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100680", "type": "external" } ], "gene_names_uniprotkb": "Ppef2", "gene_names_refseq": "Ppef2", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase with EF-hands; 3.1.3.16", "protein_names_refseq": "protein phosphatase, EF hand calcium-binding domain 2; serine/threonine-protein phosphatase with EF-hands 2", "tax_id": 10116, "disease": "", "pathway": " (rno:305246)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May play a role in phototransduction. May dephosphorylate photoactivated rhodopsin. May function as a calcium sensing regulator of ionic currents, energy production or synaptic transmission., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "3.1.3.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.53", "type": "external" }, { "id": "3.1.3.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.52", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "3.1.3.74", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.74", "type": "external" } ], "go_molecular_function": "GO:0005506 iron ion binding;GO:0030145 manganese ion binding;GO:0005509 calcium ion binding;GO:0004722 protein serine/threonine phosphatase activity;GO:0051879 Hsp90 protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0050906 detection of stimulus involved in sensory perception;GO:0007601 visual perception;GO:0070301 cellular response to hydrogen peroxide;GO:0043409 negative regulation of MAPK cascade;GO:2001234 negative regulation of apoptotic signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZN69-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZND9-1", "uniprot_id": [ { "id": "D3ZND9_RAT", "url": "https://www.uniprot.org/uniprot/D3ZND9", "type": "external" } ], "mass": 59958.0, "length": 529, "protein_name": "Serine/threonine-protein kinase RIO3", "gene_name": "Riok3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Riok3", "gene_names_refseq": "", "protein_names_uniprotkb": "Serine/threonine-protein kinase RIO3; 2.7.11.1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Serine/threonine-protein kinase involved in a ribosome quality control that takes place when ribosomes have stalled, leading to 18S non-functional rRNA decay and degradation of the 40S ribosomal subunit. Acts downstream of RNF10: specifically recognizes and binds RPS2/us5 and RPS3/us3 monoubiquitinated by RNF10, promoting degradation of the 40S ribosomal subunit in a kinase-dependent manner. The RNF10-RIOK3 ribosome quality control takes place in response to ribosome subunit imbalance or downstream the EIF2AK4/GCN2-mediated integrated stress response (ISR). Also involved in regulation of type I interferon (IFN)-dependent immune response, possibly by acting as an adapter protein essential for the recruitment of TBK1 to IRF3. Phosphorylates IFIH1 on 'Ser-828' interfering with IFIH1 filament assembly on long dsRNA and resulting in attenuated IFIH1-signaling. Can inhibit CASP10 isoform 7-mediated activation of the NF-kappa-B signaling pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.4.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.18", "type": "external" }, { "id": "3.1.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.24.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:0140036 ubiquitin-modified protein reader activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0089720 caspase binding", "go_cellular_component": "GO:0022626 cytosolic ribosome;GO:0030688 preribosome, small subunit precursor", "go_biological_process": "GO:0071359 cellular response to dsRNA;GO:0070651 nonfunctional rRNA decay;GO:0045087 innate immune response;GO:0043124 negative regulation of canonical NF-kappaB signal transduction;GO:0031333 negative regulation of protein-containing complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZND9-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZNH9-1", "uniprot_id": [ { "id": "D3ZNH9_RAT", "url": "https://www.uniprot.org/uniprot/D3ZNH9", "type": "external" } ], "mass": 34935.0, "length": 315, "protein_name": "Olfactory receptor", "gene_name": "Or2v1", "organism": "Rat", "refseq_name": "olfactory receptor Olr1386", "refseq_ac": [ { "id": "NP_999999", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999999", "type": "external" } ], "gene_names_uniprotkb": "Or2v1", "gene_names_refseq": "Olr1386; Or2v1", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1386; olfactory receptor Olr1386; olfactory receptor gene Olr1386", "tax_id": 10116, "disease": "", "pathway": " (rno:287237)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZNH9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZNW9-1", "uniprot_id": [ { "id": "D3ZNW9_RAT", "url": "https://www.uniprot.org/uniprot/D3ZNW9", "type": "external" } ], "mass": 27627.0, "length": 245, "protein_name": "TLC domain containing 5", "gene_name": "Tlcd5", "organism": "Rat", "refseq_name": "TLC domain-containing protein 5", "refseq_ac": [ { "id": "NP_001101606", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101606", "type": "external" } ], "gene_names_uniprotkb": "Tlcd5; 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Stimulates RNA polymerase I transcription of the 47S precursor rRNA. Associates with ribosomal DNA (rDNA) loci where it is involved in POLR1A recruitment. In the cytoplasm, promotes elongation-competent 80S ribosome assembly at the late stage of mRNA translation initiation. Senses cytosolic dsRNA mediating NLRP3 inflammasome formation in macrophages and type I interferon production in myeloid dendritic cells. Required for NLRP3 activation induced by viral dsRNA and bacterial RNA. In dendritic cells, required for induction of type I interferon production induced by cytoplasmic dsRNA via the activation of MAPK and NF-kappa-B signaling pathways., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.9.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.9.1.1", "type": "external" }, { "id": "6.1.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" } ], "go_molecular_function": "GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003725 double-stranded RNA binding;GO:0004386 helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0072559 NLRP3 inflammasome complex", "go_biological_process": "GO:0043410 positive regulation of MAPK cascade;GO:0006413 translational initiation;GO:0045943 positive regulation of transcription by RNA polymerase I;GO:0032481 positive regulation of type I interferon production;GO:1900227 positive regulation of NLRP3 inflammasome complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZSV6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZSY1-1", "uniprot_id": [ { "id": "D3ZSY1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZSY1", "type": "external" } ], "mass": 84127.0, "length": 784, "protein_name": "Terminal nucleotidyltransferase 4A", "gene_name": "Tent4a", "organism": "Rat", "refseq_name": "terminal nucleotidyltransferase 4A isoform 1", "refseq_ac": [ { "id": "NP_001402773", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001402773", "type": "external" } ], "gene_names_uniprotkb": "Tent4a", "gene_names_refseq": "Papd7; Pols; Tent4a", "protein_names_uniprotkb": "Terminal nucleotidyltransferase 4A; 2.7.7.19; DNA polymerase sigma; Non-canonical poly(A) RNA polymerase PAPD7; PAP-associated domain-containing protein 7; TRAMP-like complex polyadenylate polymerase; Terminal guanylyltransferase", "protein_names_refseq": "DNA polymerase sigma; PAP associated domain containing 7; non-canonical poly(A) RNA polymerase PAPD7; poly(A) RNA polymerase D7, non-canonical; polymerase (DNA directed) sigma; terminal nucleotidyltransferase 4A isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:306672)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Terminal nucleotidyltransferase that catalyzes preferentially the transfer of ATP and GTP on RNA 3' poly(A) tail creating a heterogeneous 3' poly(A) tail leading to mRNAs stabilization by protecting mRNAs from active deadenylation. Also functions as a catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.7.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19", "type": "external" }, { "id": "2.7.7.52", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.52", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:1990817 poly(A) RNA polymerase activity;GO:0070568 guanylyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0031499 TRAMP complex", "go_biological_process": "GO:0009410 response to xenobiotic stimulus;GO:0031123 RNA 3'-end processing;GO:1905870 positive regulation of 3'-UTR-mediated mRNA stabilization;GO:0060212 negative regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0043634 polyadenylation-dependent ncRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZSY1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZTB4-1", "uniprot_id": [ { "id": "D3ZTB4_RAT", "url": "https://www.uniprot.org/uniprot/D3ZTB4", "type": "external" } ], "mass": 107829.0, "length": 941, "protein_name": "Vacuolar protein sorting-associated protein 11 homolog", "gene_name": "Vps11", "organism": "Rat", "refseq_name": "vacuolar protein sorting-associated protein 11 homolog", "refseq_ac": [ { "id": "NP_001101608", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101608", "type": "external" } ], "gene_names_uniprotkb": "Vps11", "gene_names_refseq": "Vps11", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 11 homolog", "protein_names_refseq": "VPS11 CORVET/HOPS core subunit; vacuolar protein sorting 11 homolog; vacuolar protein sorting-associated protein 11 homolog", "tax_id": 10116, "disease": "hypomyelinating leukoencephalopathy (Disease Ontology:DOID:0050987); hypomyelinating leukodystrophy 12 (Disease Ontology:DOID:0060796); dystonia 32 (Disease Ontology:DOID:0060939)", "pathway": " (rno:315600)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019904 protein domain specific binding;GO:0030674 protein-macromolecule adaptor activity;GO:0000166 nucleotide binding;GO:0019905 syntaxin binding", "go_cellular_component": "GO:0030897 HOPS complex;GO:0005768 endosome;GO:0005769 early endosome;GO:0005884 actin filament;GO:0005764 lysosome", "go_biological_process": "GO:0048284 organelle fusion;GO:1902115 regulation of organelle assembly;GO:0006886 intracellular protein transport;GO:0007032 endosome organization;GO:0008333 endosome to lysosome transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZTB4-1", "record_type": "protein", "filter_code": "0000000.0000011.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZTK0-1", "uniprot_id": [ { "id": "D3ZTK0_RAT", "url": "https://www.uniprot.org/uniprot/D3ZTK0", "type": "external" } ], "mass": 25877.0, "length": 239, "protein_name": "Tetratricopeptide repeat domain 9B", "gene_name": "Ttc9b", "organism": "Rat", "refseq_name": "tetratricopeptide repeat protein 9B", "refseq_ac": [ { "id": "NP_001101948", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101948", "type": "external" } ], "gene_names_uniprotkb": "Ttc9b", "gene_names_refseq": "RGD1306256; Ttc9b", "protein_names_uniprotkb": "Tetratricopeptide repeat domain 9B", "protein_names_refseq": "tetratricopeptide repeat protein 9B", "tax_id": 10116, "disease": "", "pathway": " (rno:361528)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZTK0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZTP7-1", "uniprot_id": [ { "id": "D3ZTP7_RAT", "url": "https://www.uniprot.org/uniprot/D3ZTP7", "type": "external" } ], "mass": 34846.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or5j1", "organism": "Rat", "refseq_name": "olfactory receptor Olr539", "refseq_ac": [ { "id": "NP_001000320", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000320", "type": "external" } ], "gene_names_uniprotkb": "Or5j1", "gene_names_refseq": "Olr539; Or5j1", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 539; olfactory receptor Olr539; olfactory receptor gene Olr539", "tax_id": 10116, "disease": "", "pathway": " (rno:295790)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZTP7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZTZ6-1", "uniprot_id": [ { "id": "D3ZTZ6_RAT", "url": "https://www.uniprot.org/uniprot/D3ZTZ6", "type": "external" } ], "mass": 61541.0, "length": 558, "protein_name": "Leucine rich repeat containing 71", "gene_name": "Lrrc71", "organism": "Rat", "refseq_name": "leucine-rich repeat-containing protein 71", "refseq_ac": [ { "id": "NP_001101171", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101171", "type": "external" } ], "gene_names_uniprotkb": "Lrrc71", "gene_names_refseq": "Lrrc71; RGD1309453", "protein_names_uniprotkb": "Leucine rich repeat containing 71", "protein_names_refseq": "leucine-rich repeat-containing protein 71", "tax_id": 10116, "disease": "", "pathway": " (rno:310689)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZTZ6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZUB7-1", "uniprot_id": [ { "id": "D3ZUB7_RAT", "url": "https://www.uniprot.org/uniprot/D3ZUB7", "type": "external" } ], "mass": 91777.0, "length": 807, "protein_name": "Anaphase-promoting complex subunit 4", "gene_name": "Anapc4", "organism": "Rat", "refseq_name": "anaphase-promoting complex subunit 4", "refseq_ac": [ { "id": "NP_001100690", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100690", "type": "external" } ], "gene_names_uniprotkb": "Anapc4", "gene_names_refseq": "Anapc4", "protein_names_uniprotkb": "Anaphase-promoting complex subunit 4; Cyclosome subunit 4", "protein_names_refseq": "anaphase-promoting complex subunit 4", "tax_id": 10116, "disease": "", "pathway": " (rno:305420); (R-RNO-141430); (R-RNO-174048); (R-RNO-174084); (R-RNO-174154); (R-RNO-174178); (R-RNO-174184); (R-RNO-176407); (R-RNO-176408); (R-RNO-176412); (R-RNO-179409); (R-RNO-2467813); (R-RNO-2559582); (R-RNO-68867); (R-RNO-69017); (R-RNO-983168)", "pathway_count": 16, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019903 protein phosphatase binding", "go_cellular_component": "GO:0005680 anaphase-promoting complex;GO:0034399 nuclear periphery;GO:0005634 nucleus", "go_biological_process": "GO:0051301 cell division;GO:0031145 anaphase-promoting complex-dependent catabolic process;GO:0070979 protein K11-linked ubiquitination;GO:0030071 regulation of mitotic metaphase/anaphase transition;GO:0070936 protein K48-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZUB7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZUC2-1", "uniprot_id": [ { "id": "D3ZUC2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZUC2", "type": "external" } ], "mass": 113760.0, "length": 1004, "protein_name": "RNA helicase", "gene_name": "Mov10", "organism": "Rat", "refseq_name": "helicase MOV-10", "refseq_ac": [ { "id": "NP_001101181", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101181", "type": "external" } ], "gene_names_uniprotkb": "Mov10", "gene_names_refseq": "Capza1; Mov10", "protein_names_uniprotkb": "RNA helicase; 3.6.4.13; Moloney leukemia virus 10 protein", "protein_names_refseq": "Mov10 RISC complex RNA helicase; Mov10, Moloney leukemia virus 10; capping protein (actin filament) muscle Z-line, alpha 1; helicase MOV-10; putative helicase MOV-10", "tax_id": 10116, "disease": "hypertension (Disease Ontology:DOID:10763); primary ovarian insufficiency (Disease Ontology:DOID:5426)", "pathway": " (rno:310756)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "31291981", "class_list": "", "function": "FMRP and MOV10 have an important regulatory role in NMDAR mediated translation at the synapse. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "5.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.3", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.4.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.12", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "3.6.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.-", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "5.6.2.4", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.4", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "5.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.-", "type": "external" }, { "id": "3.1.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.-.-", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "2.7.7.49", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49", "type": "external" }, { "id": "3.1.13.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.13.1", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "7.6.2.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.2", "type": "external" }, { "id": "7.6.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.3", "type": "external" }, { "id": "7.6.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.6.2.-", "type": "external" }, { "id": "5.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.1.6", "type": "external" }, { "id": "7.2.2.-", "url": "https://www.rhea-db.org/rhea/?query=ec:7.2.2.-", "type": "external" }, { "id": "3.6.1.15", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.15", "type": "external" }, { "id": "3.6.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6", "type": "external" }, { "id": "3.1.3.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.1", "type": "external" }, { "id": "3.9.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.9.1.1", "type": "external" }, { "id": "6.1.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.12", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "2.7.4.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3", "type": "external" }, { "id": "3.1.4.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.-", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" }, { "id": "3.6.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.-.-", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" }, { "id": "5.6.2.5", "url": "https://www.rhea-db.org/rhea/?query=ec:5.6.2.5", "type": "external" }, { "id": "3.1.26.n2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.26.n2", "type": "external" } ], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0032574 5'-3' RNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0000932 P-body;GO:0036464 cytoplasmic ribonucleoprotein granule;GO:0043186 P granule", "go_biological_process": "GO:0051607 defense response to virus;GO:0035194 regulatory ncRNA-mediated post-transcriptional gene silencing;GO:0035279 miRNA-mediated gene silencing by mRNA destabilization;GO:0035195 miRNA-mediated post-transcriptional gene silencing;GO:0061014 positive regulation of mRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZUC2-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZUI1-1", "uniprot_id": [ { "id": "D3ZUI1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZUI1", "type": "external" } ], "mass": 27053.0, "length": 241, "protein_name": "Methylthioribulose-1-phosphate dehydratase", "gene_name": "Apip", "organism": "Rat", "refseq_name": "methylthioribulose-1-phosphate dehydratase", "refseq_ac": [ { "id": "NP_001099962", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099962", "type": "external" } ], "gene_names_uniprotkb": "Apip; APIP", "gene_names_refseq": "Apip; RGD1564562", "protein_names_uniprotkb": "Methylthioribulose-1-phosphate dehydratase; 4.2.1.109; APAF1-interacting protein; MTRu-1-P dehydratase", "protein_names_refseq": "methylthioribulose-1-phosphate dehydratase; probable methylthioribulose-1-phosphate dehydratase", "tax_id": 10116, "disease": "", "pathway": " (rno:295961); (R-RNO-111458); (R-RNO-9627069)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.2.1.109", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.109", "type": "external" }, { "id": "3.4.22.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.22.62", "type": "external" } ], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0046570 methylthioribulose 1-phosphate dehydratase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0012505 endomembrane system", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0051289 protein homotetramerization;GO:0006915 apoptotic process;GO:0070269 pyroptotic inflammatory response;GO:0070372 regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZUI1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZUL8-1", "uniprot_id": [ { "id": "D3ZUL8_RAT", "url": "https://www.uniprot.org/uniprot/D3ZUL8", "type": "external" } ], "mass": 76937.0, "length": 695, "protein_name": "Zinc finger CCHC domain-containing protein 8", "gene_name": "Zcchc8", "organism": "Rat", "refseq_name": "zinc finger CCHC domain-containing protein 8", "refseq_ac": [ { "id": "NP_001387897", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001387897", "type": "external" } ], "gene_names_uniprotkb": "Zcchc8", "gene_names_refseq": "Zcchc8", "protein_names_uniprotkb": "Zinc finger CCHC domain-containing protein 8; TRAMP-like complex RNA-binding factor ZCCHC8", "protein_names_refseq": "zinc finger CCHC domain-containing protein 8; zinc finger, CCHC domain containing 8", "tax_id": 10116, "disease": "", "pathway": " (rno:288661); (R-RNO-9930044)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Scaffolding subunit of the trimeric nuclear exosome targeting (NEXT) complex that is involved in the surveillance and turnover of aberrant transcripts and non-coding RNAs. NEXT functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. May be involved in pre-mRNA splicing. It is required for 3'-end maturation of telomerase RNA component (TERC), TERC 3'-end targeting to the nuclear RNA exosome, and for telomerase function., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0071013 catalytic step 2 spliceosome;GO:0031499 TRAMP complex;GO:0062141 nuclear exosome targeting complex", "go_biological_process": "GO:0006396 RNA processing;GO:0031124 mRNA 3'-end processing;GO:0180034 co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZUL8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZV49-1", "uniprot_id": [ { "id": "D3ZV49_RAT", "url": "https://www.uniprot.org/uniprot/D3ZV49", "type": "external" } ], "mass": 59036.0, "length": 551, "protein_name": "Autoimmune regulator", "gene_name": "Aire", "organism": "Rat", "refseq_name": "autoimmune regulator isoform 1", "refseq_ac": [ { "id": "NP_001421546", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421546", "type": "external" } ], "gene_names_uniprotkb": "Aire", "gene_names_refseq": "Aire", "protein_names_uniprotkb": "Autoimmune regulator", "protein_names_refseq": "autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy); autoimmune regulator isoform 1", "tax_id": 10116, "disease": "autoimmune polyendocrine syndrome type 1 (Disease Ontology:DOID:0050167); Guillain-Barre syndrome (Disease Ontology:DOID:12842); Sjogren's syndrome (Disease Ontology:DOID:12894); autoimmune polyendocrine syndrome (Disease Ontology:DOID:14040)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016604 nuclear body", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0032722 positive regulation of chemokine production;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZV49-1", "record_type": "protein", "filter_code": "0000000.1000010.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZV76-1", "uniprot_id": [ { "id": "D3ZV76_RAT", "url": "https://www.uniprot.org/uniprot/D3ZV76", "type": "external" } ], "mass": 11179.0, "length": 97, "protein_name": "Mitochondrial import inner membrane translocase subunit", "gene_name": "Timm8a2", "organism": "Rat", "refseq_name": "translocase of inner mitochondrial membrane 8A2", "refseq_ac": [ { "id": "NP_001102899", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102899", "type": "external" } ], "gene_names_uniprotkb": "Timm8a2", "gene_names_refseq": "Timm8a2", "protein_names_uniprotkb": "Mitochondrial import inner membrane translocase subunit", "protein_names_refseq": "translocase of inner mitochondrial membrane 8 homolog a2; translocase of inner mitochondrial membrane 8A2", "tax_id": 10116, "disease": "deafness-dystonia-optic neuronopathy syndrome (Disease Ontology:DOID:0050757)", "pathway": " (rno:680794)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0015031 protein transport;GO:0072655 establishment of protein localization to mitochondrion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZV76-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZVP6-1", "uniprot_id": [ { "id": "D3ZVP6_RAT", "url": "https://www.uniprot.org/uniprot/D3ZVP6", "type": "external" } ], "mass": 73495.0, "length": 646, "protein_name": "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "gene_name": "Ppwd1", "organism": "Rat", "refseq_name": "peptidylprolyl isomerase domain and WD repeat-containing protein 1", "refseq_ac": [ { "id": "NP_001099876", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099876", "type": "external" } ], "gene_names_uniprotkb": "Ppwd1", "gene_names_refseq": "Ppwd1; RGD1310204", "protein_names_uniprotkb": "Peptidylprolyl isomerase domain and WD repeat-containing protein 1; 5.2.1.8", "protein_names_refseq": "peptidylprolyl isomerase domain and WD repeat-containing protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:294711); (R-RNO-72163)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. May be involved in pre-mRNA splicing., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "5.2.1.8", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8", "type": "external" }, { "id": "2.7.7.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.6", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" } ], "go_molecular_function": "GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005681 spliceosomal complex;GO:0016604 nuclear body;GO:0071013 catalytic step 2 spliceosome;GO:0071006 U2-type catalytic step 1 spliceosome", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZVP6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZVS2-1", "uniprot_id": [ { "id": "D3ZVS2_RAT", "url": "https://www.uniprot.org/uniprot/D3ZVS2", "type": "external" } ], "mass": 51693.0, "length": 471, "protein_name": "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "gene_name": "L2hgdh", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "L2hgdh", "gene_names_refseq": "", "protein_names_uniprotkb": "L-2-hydroxyglutarate dehydrogenase, mitochondrial; 1.1.99.2", "protein_names_refseq": "", "tax_id": 10116, "disease": "2-hydroxyglutaric aciduria (Disease Ontology:DOID:0050573); L-2-hydroxyglutaric aciduria (Disease Ontology:DOID:0050574); cerebellar ataxia (Disease Ontology:DOID:0050753); hereditary spastic paraplegia (Disease Ontology:DOID:2476)", "pathway": " (R-RNO-880009)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.1.99.2", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.99.2", "type": "external" } ], "go_molecular_function": "GO:0047545 (S)-2-hydroxyglutarate dehydrogenase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0016020 membrane", "go_biological_process": "GO:0044281 small molecule metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZVS2-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZVT6-1", "uniprot_id": [ { "id": "D3ZVT6_RAT", "url": "https://www.uniprot.org/uniprot/D3ZVT6", "type": "external" } ], "mass": 34813.0, "length": 314, "protein_name": "Ankyrin repeat and SOCS box protein 7", "gene_name": "Asb7", "organism": "Rat", "refseq_name": "ankyrin repeat and SOCS box protein 7 isoform X2", "refseq_ac": [ { "id": "XP_063125298", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063125298", "type": "external" } ], "gene_names_uniprotkb": "Asb7", "gene_names_refseq": "Asb7", "protein_names_uniprotkb": "Ankyrin repeat and SOCS box protein 7", "protein_names_refseq": "ankyrin repeat and SOCS box protein 7 isoform X2", "tax_id": 10116, "disease": "", "pathway": " (rno:365277); (R-RNO-8951664); (R-RNO-983168)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Substrate-recognition component of a cullin-5-RING E3 ubiquitin-protein ligase complex (ECS complex, also named CRL5 complex), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as LZTS1, PSRC1 and SUV39H1. The ECS(ASB7) complex acts as a negative regulator of H3K9me3 histone mark by mediating ubiquitination and degradation of SUV39H1: ASB7 is recruited to heterochromatin by CBX5 (HP1 alpha), where it associates with SUV39H1, promoting the ubiquitin-proteasome-mediated degradation of SUV39H1. During mitosis, ASB7 is phosphorylated and inactivated, allowing SUV39H1 activity. The ECS(ASB7) complex also plays a role in spindle dynamics and genome integrity by targeting the mitotic progression protein PSRC1 for proteasomal degradation in a cell cycle-dependent manner. Also participates in meiosis by mediating the proper attachment between kinetochores and microtubules., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, 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"total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "4.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.3.16", "type": "external" } ], "go_molecular_function": "GO:0008700 (R,S)-4-hydroxy-2-oxoglutarate aldolase activity;GO:0042803 protein homodimerization activity;GO:0016833 oxo-acid-lyase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0033609 oxalate metabolic process;GO:0042866 pyruvate biosynthetic process;GO:0019470 trans-4-hydroxy-L-proline catabolic process;GO:0046487 glyoxylate metabolic process;GO:0009436 glyoxylate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A2K1-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A2P4-1", "uniprot_id": [ { "id": "D4A2P4_RAT", "url": "https://www.uniprot.org/uniprot/D4A2P4", "type": "external" } ], "mass": 25592.0, "length": 224, "protein_name": "Sperm microtubule inner protein 5", "gene_name": "Spmip5", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Spmip5", "gene_names_refseq": "", "protein_names_uniprotkb": "Sperm microtubule inner protein 5", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0036126 sperm flagellum;GO:0160111 axonemal A tubule inner sheath", "go_biological_process": "GO:0030317 flagellated sperm motility", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A2P4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A3D2-1", "uniprot_id": [ { "id": "D4A3D2_RAT", "url": "https://www.uniprot.org/uniprot/D4A3D2", "type": "external" } ], "mass": 56554.0, "length": 490, "protein_name": "[histone H3]-lysine(4) N-trimethyltransferase", "gene_name": "Smyd1", "organism": "Rat", "refseq_name": "histone-lysine N-methyltransferase SMYD1", "refseq_ac": [ { "id": "NP_001100065", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100065", "type": "external" } ], "gene_names_uniprotkb": "Smyd1", "gene_names_refseq": "Smyd1", "protein_names_uniprotkb": "[histone H3]-lysine(4) N-trimethyltransferase; 2.1.1.354; SET and MYND domain-containing protein 1", "protein_names_refseq": "SET and MYND domain-containing protein 1; histone-lysine N-methyltransferase SMYD1", "tax_id": 10116, "disease": "", "pathway": " (rno:297333)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "27663768;32977624", "class_list": "", "function": "Role of Muscle-Specific Histone Methyltransferase (Smyd1) in Exercise-Induced Cardioprotection against Pathological Remodeling after Myocardial Infarction. Publication Status: Online-Only, [RefSeq, PubMed]; Smyd1 is responsible for restricting growth in the adult heart, with its absence leading to cellular hypertrophy, organ remodeling, and fulminate heart failure. Molecular studies reveal Smyd1 to be a muscle-specific regulator of gene expression and indicate that Smyd1 modulates expression of gene isoforms whose expression is associated with cardiac pathology. Activation of Smyd1 can prevent pathological cell growth., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.1.1.354", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.354", "type": "external" }, { "id": "2.1.1.359", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.359", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "2.1.1.355", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.355", "type": "external" }, { "id": "2.1.1.362", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.362", "type": "external" }, { "id": "2.1.1.361", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.361", "type": "external" } ], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity;GO:0140999 histone H3K4 trimethyltransferase activity;GO:0042800 histone H3K4 methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0010831 positive regulation of myotube differentiation;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0007507 heart development;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D4A3D2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A3Q1-1", "uniprot_id": [ { "id": "D4A3Q1_RAT", "url": "https://www.uniprot.org/uniprot/D4A3Q1", "type": "external" } ], "mass": 30881.0, "length": 305, "protein_name": "Keratin associated protein 10-9", "gene_name": "Krtap10-9", "organism": "Rat", "refseq_name": "uncharacterized protein LOC690478", "refseq_ac": [ { "id": "NP_001103065", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103065", "type": "external" } ], "gene_names_uniprotkb": "Krtap10-9; Krtap10-1l1; LOC690478", "gene_names_refseq": "Krtap10-9", "protein_names_uniprotkb": "Keratin associated protein 10-9", "protein_names_refseq": "uncharacterized protein LOC690478", "tax_id": 10116, "disease": "", "pathway": " (rno:690478); (R-RNO-6805567)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0045095 keratin filament", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A3Q1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A426-1", "uniprot_id": [ { "id": "D4A426_RAT", "url": "https://www.uniprot.org/uniprot/D4A426", "type": "external" } ], "mass": 37964.0, "length": 355, "protein_name": "Homeobox B2", "gene_name": "Hoxb2", "organism": "Rat", "refseq_name": "homeobox protein Hox-B2", "refseq_ac": [ { "id": "NP_001386664", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386664", "type": "external" } ], "gene_names_uniprotkb": "Hoxb2", "gene_names_refseq": "Hoxb2; Hoxbes2", "protein_names_uniprotkb": "Homeobox B2", "protein_names_refseq": "Hoxb2-like epididymal protein; homeo box B2-like; homeobox protein Hox-B2", "tax_id": 10116, "disease": "", "pathway": " (rno:100361765)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "17065603;17494099", "class_list": "", "function": "HOXBES2 expression could be regulated by androgens, and its expression level is closely associated with the postnatal development of the epididymis., [RefSeq, PubMed]; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB, UniProtKB]; We have identified and characterized a novel epididymal homeoprotein different from HOXB2 protein and hereafter referred to as HOXBES2, (HOXB2 homeodomain containing epididymis-specific sperm protein) with a probable role in fertilization., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0021569 rhombomere 3 development;GO:0021570 rhombomere 4 development;GO:0048857 neural nucleus development;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D4A426-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A434-1", "uniprot_id": [ { "id": "D4A434_RAT", "url": "https://www.uniprot.org/uniprot/D4A434", "type": "external" } ], "mass": 17874.0, "length": 166, "protein_name": "Ribonuclease H2, subunit C", "gene_name": "Rnaseh2c", "organism": "Rat", "refseq_name": "ribonuclease H2 subunit C", "refseq_ac": [ { "id": "NP_001388632", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001388632", "type": "external" } ], "gene_names_uniprotkb": "Rnaseh2c", "gene_names_refseq": "Rnaseh2c", "protein_names_uniprotkb": "Ribonuclease H2, subunit C", "protein_names_refseq": "AYP1 protein; ribonuclease H2 subunit C", "tax_id": 10116, "disease": "Aicardi-Goutieres syndrome (Disease Ontology:DOID:0050629)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0032299 ribonuclease H2 complex", "go_biological_process": "GO:0006401 RNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A434-1", "record_type": "protein", "filter_code": "0000000.0000010.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A499-1", "uniprot_id": [ { "id": "D4A499_RAT", "url": "https://www.uniprot.org/uniprot/D4A499", "type": "external" } ], "mass": 22621.0, "length": 212, "protein_name": "Phospholipase A2 inhibitor and Ly6/Plaur domain containing", "gene_name": "Pinlyp", "organism": "Rat", "refseq_name": "phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein precursor", "refseq_ac": [ { "id": "NP_001100958", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100958", "type": "external" } ], "gene_names_uniprotkb": "Pinlyp", "gene_names_refseq": "Pinlyp; RGD1565787", "protein_names_uniprotkb": "Phospholipase A2 inhibitor and Ly6/Plaur domain containing", "protein_names_refseq": "phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein precursor; phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein", "tax_id": 10116, "disease": "", "pathway": " (rno:308429)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, 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"ly-6/neurotoxin-like protein 1 isoform X1", "refseq_ac": [ { "id": "XP_063119334", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063119334", "type": "external" } ], "gene_names_uniprotkb": "Lynx1", "gene_names_refseq": "Lynx1", "protein_names_uniprotkb": "Ly-6/neurotoxin-like protein 1", "protein_names_refseq": "ly-6/neurotoxin-like protein 1 isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030548 acetylcholine receptor regulator activity;GO:0033130 acetylcholine receptor binding;GO:0008200 ion channel inhibitor activity;GO:0030550 acetylcholine receptor inhibitor activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030425 dendrite;GO:0045202 synapse", "go_biological_process": "GO:0007271 synaptic transmission, cholinergic;GO:0095500 acetylcholine receptor signaling pathway;GO:0099601 regulation of neurotransmitter receptor activity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A6F2-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A6X9-1", "uniprot_id": [ { "id": "D4A6X9_RAT", "url": "https://www.uniprot.org/uniprot/D4A6X9", "type": "external" } ], "mass": 36364.0, "length": 332, "protein_name": "18S rRNA aminocarboxypropyltransferase", "gene_name": "Tsr3", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tsr3", "gene_names_refseq": "", "protein_names_uniprotkb": "18S rRNA aminocarboxypropyltransferase; 2.5.1.157", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.5.1.157", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.157", "type": "external" } ], "go_molecular_function": "GO:0016740 transferase activity;GO:1904047 S-adenosyl-L-methionine binding;GO:0106388 rRNA small subunit aminocarboxypropyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0000455 enzyme-directed rRNA pseudouridine synthesis;GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A6X9-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A7B5-1", "uniprot_id": [ { "id": "D4A7B5_RAT", "url": "https://www.uniprot.org/uniprot/D4A7B5", "type": "external" } ], "mass": 25800.0, "length": 234, "protein_name": "NK2 homeobox 8", "gene_name": "Nkx2-8", "organism": "Rat", "refseq_name": "homeobox protein Nkx-2.8", "refseq_ac": [ { "id": "NP_001100202", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100202", "type": "external" } ], "gene_names_uniprotkb": "Nkx2-8", "gene_names_refseq": "Nkx2-8; Nkx2-9", "protein_names_uniprotkb": "NK2 homeobox 8", "protein_names_refseq": "NK2 transcription factor related, locus 9; homeobox protein Nkx-2.8", "tax_id": 10116, "disease": "congenital heart disease (Disease Ontology:DOID:1682)", "pathway": " (rno:299061)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0003690 double-stranded DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006366 transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A7B5-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A7D3-1", "uniprot_id": [ { "id": "D4A7D3_RAT", "url": "https://www.uniprot.org/uniprot/D4A7D3", "type": "external" } ], "mass": 83388.0, "length": 729, "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "Tbk1", "organism": "Rat", "refseq_name": "serine/threonine-protein kinase TBK1", "refseq_ac": [ { "id": "NP_001100256", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100256", "type": "external" } ], "gene_names_uniprotkb": "Tbk1", "gene_names_refseq": "Tbk1", "protein_names_uniprotkb": "Serine/threonine-protein kinase TBK1; 2.7.11.1; T2K; TANK-binding kinase 1", "protein_names_refseq": "serine/threonine-protein kinase TBK1", "tax_id": 10116, "disease": "frontotemporal dementia and/or amyotrophic lateral sclerosis 4 (Disease Ontology:DOID:0110069); brain disease (Disease Ontology:DOID:936)", "pathway": " (rno:299827); (R-RNO-168928); (R-RNO-3134975); (R-RNO-3249367); (R-RNO-3270619); (R-RNO-5205685); (R-RNO-5357786); (R-RNO-5357905); (R-RNO-9008059); (R-RNO-936440); (R-RNO-936964); (R-RNO-9824878)", "pathway_count": 12, "publication_count": 5, "publication_id_list": "29393594;32757223;33168920;36805078;37935918", "class_list": "", "function": "Hypoxic postconditioning restores mitophagy against transient global cerebral ischemia via Parkin-induced posttranslational modification of TBK1., [RefSeq, PubMed]; Mutant p53[R211*] ameliorates inflammatory arthritis in AIA rats via inhibition of TBK1-IRF3 innate immune response., [RefSeq, PubMed]; TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models., [RefSeq, PubMed]; TBK1 regulates regeneration of pancreatic beta-cells. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.3.2.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.31", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.4.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.18", "type": "external" }, { "id": "3.1.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.24.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" } ], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0051219 phosphoprotein binding;GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0032727 positive regulation of interferon-alpha production;GO:0006468 protein phosphorylation;GO:0010629 negative regulation of gene expression;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "D4A7D3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A7F7-1", "uniprot_id": [ { "id": "D4A7F7_RAT", "url": "https://www.uniprot.org/uniprot/D4A7F7", "type": "external" } ], "mass": 58037.0, "length": 519, "protein_name": "DDB1- and CUL4-associated factor 4", "gene_name": "Dcaf4", "organism": "Rat", "refseq_name": "DDB1- and CUL4-associated factor 4 isoform X1", "refseq_ac": [ { "id": "XP_006240409", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006240409", "type": "external" } ], "gene_names_uniprotkb": "Dcaf4", "gene_names_refseq": "Dcaf4; Wdr21", "protein_names_uniprotkb": "DDB1- and CUL4-associated factor 4; WD repeat-containing protein 21A", "protein_names_refseq": "DDB1- and CUL4-associated factor 4 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-8951664)", "pathway_count": 1, 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May play a role in the innate defense and homeostasis of certain epithelial surfaces., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane", "go_biological_process": "GO:0008283 cell population proliferation;GO:0016477 cell migration;GO:0060840 artery development;GO:0007224 smoothened signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A9N1-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A9T0-1", "uniprot_id": [ { "id": "D4A9T0_RAT", "url": "https://www.uniprot.org/uniprot/D4A9T0", "type": "external" } ], "mass": 126984.0, "length": 1200, "protein_name": "Caskin-2", "gene_name": "Caskin2", "organism": "Rat", "refseq_name": "caskin-2", "refseq_ac": [ { "id": "NP_001100535", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100535", "type": "external" } ], "gene_names_uniprotkb": "Caskin2", "gene_names_refseq": "Caskin2", "protein_names_uniprotkb": "Caskin-2", "protein_names_refseq": "caskin-2", "tax_id": 10116, "disease": "", "pathway": " (rno:303678)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A9T0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A9V5-1", "uniprot_id": [ { "id": "D4A9V5_RAT", "url": "https://www.uniprot.org/uniprot/D4A9V5", "type": "external" } ], "mass": 84743.0, "length": 758, "protein_name": "Lysyl oxidase homolog 4", "gene_name": "Loxl4", "organism": "Rat", "refseq_name": "lysyl oxidase homolog 4 isoform 2 precursor", "refseq_ac": [ { "id": "NP_001101062", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101062", "type": "external" } ], "gene_names_uniprotkb": "Loxl4", "gene_names_refseq": "Loxl4", "protein_names_uniprotkb": "Lysyl oxidase homolog 4; 1.4.3.13; Lysyl oxidase-like protein 4; Lysyl oxidase-related protein C", "protein_names_refseq": "lysyl oxidase homolog 4 isoform 2 precursor; lysyl oxidase homolog 4", "tax_id": 10116, "disease": "", "pathway": " (rno:309380); (R-RNO-1566948); (R-RNO-2243919)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the oxidative deamination of lysine and hydroxylysine residues in collagen and elastin, resulting in the formation of covalent cross-linkages, and the stabilization of collagen and elastin fibers., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.4.3.13", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.13", "type": "external" }, { "id": "3.4.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.24.-", "type": "external" } ], "go_molecular_function": "GO:0005507 copper ion binding;GO:0004720 protein-lysine 6-oxidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0016020 membrane;GO:0031012 extracellular matrix;GO:0043235 receptor complex", "go_biological_process": "GO:0030199 collagen fibril organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A9V5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A9Z3-1", "uniprot_id": [ { "id": "D4A9Z3_RAT", "url": "https://www.uniprot.org/uniprot/D4A9Z3", "type": "external" } ], "mass": 55591.0, "length": 493, "protein_name": "Kelch-like protein 42", "gene_name": "Klhl42", "organism": "Rat", "refseq_name": "kelch-like protein 42", "refseq_ac": [ { "id": "NP_001102727", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102727", "type": "external" } ], "gene_names_uniprotkb": "Klhl42; 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The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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gestational diabetes (Disease Ontology:DOID:11714); alcoholic hepatitis (Disease Ontology:DOID:12351); Guillain-Barre syndrome (Disease Ontology:DOID:12842); autistic disorder (Disease Ontology:DOID:12849); cardiovascular system disease (Disease Ontology:DOID:1287); uveitis (Disease Ontology:DOID:13141); proliferative diabetic retinopathy (Disease Ontology:DOID:13207); Behcet's disease (Disease Ontology:DOID:13241); temporal arteritis (Disease Ontology:DOID:13375); anterior uveitis (Disease Ontology:DOID:1407); toxic shock syndrome (Disease Ontology:DOID:14115); aggressive periodontitis (Disease Ontology:DOID:1474); cystic fibrosis (Disease Ontology:DOID:1485); fungal infectious disease (Disease Ontology:DOID:1564); thrombocytopenia (Disease Ontology:DOID:1588); multiple sclerosis (Disease Ontology:DOID:2377); asthma (Disease Ontology:DOID:2841); endometriosis (Disease Ontology:DOID:289); severe acute respiratory syndrome (Disease Ontology:DOID:2945); pulmonary tuberculosis (Disease Ontology:DOID:2957); interstitial lung disease (Disease Ontology:DOID:3082); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); ischemia (Disease Ontology:DOID:326); bipolar disorder (Disease Ontology:DOID:3312); coronary artery disease (Disease Ontology:DOID:3393); systemic scleroderma (Disease Ontology:DOID:418); macular degeneration (Disease Ontology:DOID:4448); macular retinal edema (Disease Ontology:DOID:4449); rhinitis (Disease Ontology:DOID:4483); periapical granuloma (Disease Ontology:DOID:4617); pancreatitis (Disease Ontology:DOID:4989); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); retinal detachment (Disease Ontology:DOID:5327); pneumonia (Disease Ontology:DOID:552); myocardial infarction (Disease Ontology:DOID:5844); fibromyalgia (Disease Ontology:DOID:631); hepatocellular carcinoma (Disease Ontology:DOID:684); rheumatoid arthritis (Disease Ontology:DOID:7148); end stage renal disease (Disease Ontology:DOID:783); lipodystrophy (Disease Ontology:DOID:811); myocarditis (Disease Ontology:DOID:820); periapical periodontitis (Disease Ontology:DOID:823); ulcerative colitis (Disease Ontology:DOID:8577); skin melanoma (Disease Ontology:DOID:8923); systemic lupus erythematosus (Disease Ontology:DOID:9074); acute myeloid leukemia (Disease Ontology:DOID:9119); viral infectious disease (Disease Ontology:DOID:934); ethmoid sinusitis (Disease Ontology:DOID:9507); pulmonary emphysema (Disease Ontology:DOID:9675); type 1 diabetes mellitus (Disease Ontology:DOID:9744); obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:287562); (R-RNO-380108)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 66, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0016004 phospholipase activator activity;GO:0008009 chemokine activity;GO:0048020 CCR chemokine receptor binding;GO:0031727 CCR2 chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0001525 angiogenesis;GO:0006954 inflammatory response;GO:0007267 cell-cell signaling;GO:0030335 positive regulation of cell migration;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ABS1-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ABX3-1", "uniprot_id": [ { "id": "D4ABX3_RAT", "url": "https://www.uniprot.org/uniprot/D4ABX3", "type": "external" } ], "mass": 36835.0, "length": 330, "protein_name": "Endonuclease 8-like 2", "gene_name": "Neil2", "organism": "Rat", "refseq_name": "endonuclease 8-like 2", "refseq_ac": [ { "id": "NP_001100740", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100740", "type": "external" } ], "gene_names_uniprotkb": "Neil2", "gene_names_refseq": "Neil2", "protein_names_uniprotkb": "Endonuclease 8-like 2; 4.2.99.18; DNA glycosylase/AP lyase Neil2; DNA-(apurinic or apyrimidinic site) lyase Neil2; Endonuclease VIII-like 2; Nei-like protein 2", "protein_names_refseq": "endonuclease 8-like 2; endonuclease VIII-like 2", "tax_id": 10116, "disease": "", "pathway": " (rno:305957); (R-RNO-110329); (R-RNO-5649702)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "21145906", "class_list": "", "function": "In the spleen aniline-induced oxidative stress is associated with an induction of NEIL1/2., [RefSeq, PubMed]; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5-hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double-stranded DNA (DNA bubbles). Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" }, { "id": "2.7.1.78", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.78", "type": "external" }, { "id": "3.1.3.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.32", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "4.2.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.-", "type": "external" } ], "go_molecular_function": "GO:0008017 microtubule binding;GO:0008270 zinc ion binding;GO:0003684 damaged DNA binding;GO:0019104 DNA N-glycosylase activity;GO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0015630 microtubule cytoskeleton;GO:0072686 mitotic spindle", "go_biological_process": "GO:0006284 base-excision repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4ABX3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ACA6-1", "uniprot_id": [ { "id": "D4ACA6_RAT", "url": "https://www.uniprot.org/uniprot/D4ACA6", "type": "external" } ], "mass": 119673.0, "length": 1089, "protein_name": "Mitotic deacetylase associated SANT domain protein", "gene_name": "Mideas", "organism": "Rat", "refseq_name": "mitotic deacetylase-associated SANT domain protein", "refseq_ac": [ { "id": "NP_001162587", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162587", "type": "external" } ], "gene_names_uniprotkb": "Mideas; Elmsan1", "gene_names_refseq": "Elmsan1; Mideas; RGD1306119", "protein_names_uniprotkb": "Mitotic deacetylase associated SANT domain protein", "protein_names_refseq": "ELM2 and Myb/SANT domain containing 1; ELM2 and Myb/SANT-like domain containing 1; ELM2 and SANT domain-containing protein 1; mitotic deacetylase-associated SANT domain protein", "tax_id": 10116, "disease": "", "pathway": " (rno:314306)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;29393594", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003714 transcription corepressor activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex;GO:0000118 histone deacetylase complex;GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D4ACA6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ACC1-1", "uniprot_id": [ { "id": "D4ACC1_RAT", "url": "https://www.uniprot.org/uniprot/D4ACC1", "type": "external" } ], "mass": 32111.0, "length": 279, "protein_name": "Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide", "gene_name": "Dapp1", "organism": "Rat", "refseq_name": "dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide", "refseq_ac": [ { "id": "NP_001102038", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102038", "type": "external" } ], "gene_names_uniprotkb": "Dapp1", "gene_names_refseq": "Dapp1", "protein_names_uniprotkb": "Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; B lymphocyte adapter protein Bam32; B-cell adapter molecule of 32 kDa", "protein_names_refseq": "dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; dual adaptor for phosphotyrosine and 3-phosphoinositides 1", "tax_id": 10116, "disease": "", "pathway": " (rno:362046); (R-RNO-983695)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0043325 phosphatidylinositol-3,4-bisphosphate binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4ACC1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ACE1-1", "uniprot_id": [ { "id": "D4ACE1_RAT", "url": "https://www.uniprot.org/uniprot/D4ACE1", "type": "external" } ], "mass": 27485.0, "length": 251, "protein_name": "Homeobox protein Hox-D4", "gene_name": "Hoxd4", "organism": "Rat", "refseq_name": "homeobox protein Hox-D4", "refseq_ac": [ { "id": "NP_001099355", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099355", "type": "external" } ], "gene_names_uniprotkb": "Hoxd4", "gene_names_refseq": "Hoxd4", "protein_names_uniprotkb": "Homeobox protein Hox-D4", "protein_names_refseq": "homeobox protein Hox-D4", "tax_id": 10116, "disease": "leukemia (Disease Ontology:DOID:1240)", "pathway": " (rno:288153)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0048863 stem cell differentiation;GO:0009952 anterior/posterior pattern specification;GO:0048704 embryonic skeletal system morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ACE1-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ACK0-1", "uniprot_id": [ { "id": "D4ACK0_RAT", "url": "https://www.uniprot.org/uniprot/D4ACK0", "type": "external" } ], "mass": 43692.0, "length": 396, "protein_name": "G protein-coupled receptor 84", "gene_name": "Gpr84", "organism": "Rat", "refseq_name": "G-protein coupled receptor 84", "refseq_ac": [ { "id": "NP_001102979", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102979", "type": "external" } ], "gene_names_uniprotkb": "Gpr84", "gene_names_refseq": "Gpr84", "protein_names_uniprotkb": "G protein-coupled receptor 84", "protein_names_refseq": "G-protein coupled receptor 84", "tax_id": 10116, "disease": "", "pathway": " (rno:688730); (R-RNO-6798695)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23449982", "class_list": "", "function": "Medium-chain fatty acid-sensing receptor, GPR84, is a proinflammatory receptor., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001604 urotensin II receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0007218 neuropeptide signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4ACK0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ACM0-1", "uniprot_id": [ { "id": "D4ACM0_RAT", "url": "https://www.uniprot.org/uniprot/D4ACM0", "type": "external" } ], "mass": 13263.0, "length": 116, "protein_name": "Histone H2A", "gene_name": "H2ab2", "organism": "Rat", "refseq_name": "H2A.B variant histone 3", "refseq_ac": [ { "id": "NP_001100439", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100439", "type": "external" } ], "gene_names_uniprotkb": "H2ab2; H2ab3; H2afb3", "gene_names_refseq": "H2ab2; H2ab3; H2afb3; RGD1561666", "protein_names_uniprotkb": "Histone H2A", "protein_names_refseq": "H2A histone family, member B3; H2A.B variant histone 3", "tax_id": 10116, "disease": "", "pathway": " (rno:302783); (R-RNO-110330); (R-RNO-110331); (R-RNO-212300); (R-RNO-2299718); (R-RNO-2559580); (R-RNO-2559582); (R-RNO-2559586); (R-RNO-427359); (R-RNO-427413); (R-RNO-5250924); (R-RNO-5578749); (R-RNO-5625886); (R-RNO-606279); (R-RNO-68616); (R-RNO-73728); (R-RNO-73772); (R-RNO-8936459); (R-RNO-9018519); (R-RNO-9764725); (R-RNO-9841922); (R-RNO-9843940); (R-RNO-9843970); (R-RNO-9909649); (R-RNO-9940951); (R-RNO-9943411); (R-RNO-9943962); (R-RNO-9970672)", "pathway_count": 28, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, 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"0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AD42-1", "uniprot_id": [ { "id": "D4AD42_RAT", "url": "https://www.uniprot.org/uniprot/D4AD42", "type": "external" } ], "mass": 35617.0, "length": 313, "protein_name": "Olfactory receptor", "gene_name": "Or8k40", "organism": "Rat", "refseq_name": "olfactory receptor Olr514", "refseq_ac": [ { "id": "NP_001000314", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000314", "type": "external" } ], "gene_names_uniprotkb": "Or8k40", "gene_names_refseq": "Olr514; Or8k40", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 514; olfactory receptor Olr514; olfactory receptor gene Olr514", "tax_id": 10116, "disease": "", "pathway": " (rno:295767)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AD42-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AD44-1", "uniprot_id": [ { "id": "D4AD44_RAT", "url": "https://www.uniprot.org/uniprot/D4AD44", "type": "external" } ], "mass": 24979.0, "length": 227, "protein_name": "Josephin-2", "gene_name": "Josd2", "organism": "Rat", "refseq_name": "josephin-2 isoform X1", "refseq_ac": [ { "id": "XP_006229058", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006229058", "type": "external" } ], "gene_names_uniprotkb": "Josd2", "gene_names_refseq": "Josd2; RGD1307305", "protein_names_uniprotkb": "Josephin-2; 3.4.19.12; Josephin domain-containing protein 2", "protein_names_refseq": "josephin-2 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-5689877)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cleaves 'Lys-63'-linked poly-ubiquitin chains, and with lesser efficiency 'Lys-48'-linked poly-ubiquitin chains (in vitro). May act as a deubiquitinating enzyme., [UniProtKB, UniProtKB]; Deubiquitinates monoubiquitinated probes (in vitro). When ubiquitinated, cleaves 'Lys-63'-linked and 'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme. May increase macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis. May enhance membrane dynamics and cell motility independently of its catalytic activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" } ], "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity;GO:0101005 deubiquitinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AD44-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4AD59-1", "uniprot_id": [ { "id": "D4AD59_RAT", "url": "https://www.uniprot.org/uniprot/D4AD59", "type": "external" } ], "mass": 35564.0, "length": 319, "protein_name": "Olfactory receptor", "gene_name": "Or7a41", "organism": "Rat", "refseq_name": "olfactory receptor Olr1075", "refseq_ac": [ { "id": "NP_001000421", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000421", "type": "external" } ], "gene_names_uniprotkb": "Or7a41", "gene_names_refseq": "Olr1075; Or7a41", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1075; olfactory receptor Olr1075; olfactory receptor gene Olr1075", "tax_id": 10116, "disease": "", "pathway": " (rno:299596)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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Olr485", "gene_names_refseq": "Olr485; Or8k1", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 485; olfactory receptor Olr485; olfactory receptor gene Olr485", "tax_id": 10116, "disease": "", "pathway": " (rno:295751)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ADA6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ADE7-1", "uniprot_id": [ { "id": "D4ADE7_RAT", "url": "https://www.uniprot.org/uniprot/D4ADE7", "type": "external" } ], "mass": 49412.0, "length": 458, "protein_name": "DNA-directed RNA polymerase I subunit RPA34", "gene_name": "Polr1g", "organism": "Rat", "refseq_name": "DNA-directed RNA polymerase I subunit RPA34", "refseq_ac": [ { "id": "NP_001102886", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102886", "type": "external" } ], "gene_names_uniprotkb": "Polr1g; 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Through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters., [UniProtKB, UniProtKB]; DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0001650 fibrillar center;GO:0005736 RNA polymerase I complex", "go_biological_process": "GO:1990830 cellular response to leukemia inhibitory factor;GO:0006362 transcription elongation by RNA polymerase I;GO:0006352 DNA-templated transcription initiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4ADH7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4ADI7-1", "uniprot_id": [ { "id": "D4ADI7_RAT", "url": "https://www.uniprot.org/uniprot/D4ADI7", "type": "external" } ], "mass": 22298.0, "length": 206, "protein_name": "Transmembrane 4 L six family member 19", "gene_name": "Tm4sf19", "organism": "Rat", "refseq_name": "transmembrane 4 L6 family member 19", "refseq_ac": [ { "id": "NP_001099343", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099343", "type": "external" } ], "gene_names_uniprotkb": "Tm4sf19", "gene_names_refseq": "RGD1560486; 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Mfi2", "gene_names_refseq": "Magea1; Meltf; Mfi2", "protein_names_uniprotkb": "Melanotransferrin; Membrane-bound transferrin-like protein p97", "protein_names_refseq": "antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5; melanoma antigen, family A, 1; melanotransferrin precursor", "tax_id": 10116, "disease": "chromosome 3q29 microdeletion syndrome (Disease Ontology:DOID:0060419)", "pathway": " (rno:288038); (R-RNO-163125); (R-RNO-381426); (R-RNO-8957275)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "15469901", "class_list": "", "function": "Compared to transferrin, soluble melanotransferrin (Magea1) plays little or no role in Fe supply to the brain and erythropoietic tissue., [RefSeq, PubMed]; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, 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Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRG5 is specifically coupled to G(s) G proteins and mediates activation of adenylate cyclase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007186 G protein-coupled receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M644-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M9Z0-1", "uniprot_id": [ { "id": "F1M9Z0_RAT", "url": "https://www.uniprot.org/uniprot/F1M9Z0", "type": "external" } ], "mass": 68944.0, "length": 614, "protein_name": "Zinc finger and SCAN domain-containing protein 2", "gene_name": "Zscan2", "organism": "Rat", "refseq_name": "zinc finger and SCAN domain-containing protein 2", "refseq_ac": [ { "id": "NP_001414652", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414652", "type": "external" } ], "gene_names_uniprotkb": "Zscan2; LOC683603", "gene_names_refseq": "Zscan2", "protein_names_uniprotkb": "Zinc finger and SCAN domain-containing protein 2", "protein_names_refseq": "zinc finger and SCAN domain-containing protein 2", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "May be involved in transcriptional regulation during the post-meiotic stages of spermatogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1M9Z0-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1MAN8-1", "uniprot_id": [ { "id": "F1MAN8_RAT", "url": "https://www.uniprot.org/uniprot/F1MAN8", "type": "external" } ], "mass": 403778.0, "length": 3713, "protein_name": "Laminin subunit alpha-5", "gene_name": "Lama5", "organism": "Rat", "refseq_name": "laminin subunit alpha-5 precursor", "refseq_ac": [ { "id": "NP_001178538", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178538", "type": "external" } ], "gene_names_uniprotkb": "Lama5", "gene_names_refseq": "Lama5", "protein_names_uniprotkb": "Laminin subunit alpha-5; Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha", "protein_names_refseq": "laminin subunit alpha-5 precursor; laminin, alpha 5", "tax_id": 10116, "disease": "bent bone dysplasia syndrome 2 (Disease Ontology:DOID:0060993); nephrotic syndrome type 26 (Disease Ontology:DOID:0061193); familial nephrotic syndrome (Disease Ontology:DOID:2590); cystic kidney disease (Disease Ontology:DOID:2975)", "pathway": " (rno:140433)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "24090084;30153280", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 9, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 9, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 9, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 9, "disease_count": 4, "glyco_site_count": 11, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0048018 receptor ligand activity;GO:0005201 extracellular matrix structural constituent;GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005615 extracellular space;GO:0031012 extracellular matrix;GO:0031594 neuromuscular junction;GO:0043083 synaptic cleft", "go_biological_process": "GO:0007155 cell adhesion;GO:0007229 integrin-mediated signaling pathway;GO:0016477 cell migration;GO:0030155 regulation of cell adhesion;GO:0042127 regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "F1MAN8-1", "record_type": "protein", "filter_code": "0000000.0000111.001000.000000000000001000.1000000001000.101.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F7EMB9-1", "uniprot_id": [ { "id": "F7EMB9_RAT", "url": "https://www.uniprot.org/uniprot/F7EMB9", "type": "external" } ], "mass": 106384.0, "length": 932, "protein_name": "Toll-like receptor 11", "gene_name": "Tlr11", "organism": "Rat", "refseq_name": "toll-like receptor 11", "refseq_ac": [ { "id": "NP_001138251", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138251", "type": "external" } ], "gene_names_uniprotkb": "Tlr11", "gene_names_refseq": "RGD1564460; Tlr11", "protein_names_uniprotkb": "Toll-like receptor 11", "protein_names_refseq": "toll-like receptor 11", "tax_id": 10116, "disease": "", "pathway": " (rno:498491)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0009617 response to bacterium;GO:0002224 toll-like receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F7EMB9-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F7F172-1", "uniprot_id": [ { "id": "F7F172_RAT", "url": "https://www.uniprot.org/uniprot/F7F172", "type": "external" } ], "mass": 45573.0, "length": 406, "protein_name": "12S rRNA N(4)-cytidine methyltransferase METTL15", "gene_name": "Mettl15", "organism": "Rat", "refseq_name": "12S rRNA N4-methylcytidine (m4C) methyltransferase isoform a", "refseq_ac": [ { "id": "NP_001418439", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418439", "type": "external" } ], "gene_names_uniprotkb": "Mettl15", "gene_names_refseq": "Mettl15; RGD1304978", "protein_names_uniprotkb": "12S rRNA N(4)-cytidine methyltransferase METTL15; Methyltransferase 5 domain-containing protein 1; Methyltransferase-like protein 15", "protein_names_refseq": "12S rRNA N4-methylcytidine (m4C) methyltransferase isoform a; 12S rRNA N4-methylcytidine (m4C) methyltransferase; methyltransferase like 15; probable methyltransferase-like protein 15", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "N4-methylcytidine (m4C) methyltransferase responsible for the methylation of position C839 in mitochondrial 12S rRNA. Involved in the stabilization of 12S rRNA folding, therefore facilitating the assembly of the mitochondrial small ribosomal subunits., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0071424 rRNA (cytosine-N4-)-methyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0070475 rRNA base methylation;GO:0180026 mitochondrial small ribosomal subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F7F172-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F7FAP6-1", "uniprot_id": [ { "id": "F7FAP6_RAT", "url": "https://www.uniprot.org/uniprot/F7FAP6", "type": "external" } ], "mass": 9192.0, "length": 80, "protein_name": "WAP four-disulfide core domain 15B", "gene_name": "Wfdc15b", "organism": "Rat", "refseq_name": "WAP four-disulfide core domain protein 15B precursor", "refseq_ac": [ { "id": "NP_001382049", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382049", "type": "external" } ], "gene_names_uniprotkb": "Wfdc15b", "gene_names_refseq": "Pi3; Serpina1c; Skalp; Wfdc14; Wfdc15b", "protein_names_uniprotkb": "WAP four-disulfide core domain 15B", "protein_names_refseq": "WAP four-disulfide core domain protein 15B precursor; WAP four-disulfide core domain protein 15B; WAP-type four-disulfide core 14; elafin; protease inhibitor 3, skin-derived", "tax_id": 10116, "disease": "", "pathway": " (rno:408230)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0019731 antibacterial humoral response;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F7FAP6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F7FHP0-1", "uniprot_id": [ { "id": "F7FHP0_RAT", "url": "https://www.uniprot.org/uniprot/F7FHP0", "type": "external" } ], "mass": 52621.0, "length": 455, "protein_name": "Angiopoietin-related protein 3", "gene_name": "Angptl3", "organism": "Rat", "refseq_name": "angiopoietin-related protein 3 isoform 1 precursor", "refseq_ac": [ { "id": "NP_001386181", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001386181", "type": "external" } ], "gene_names_uniprotkb": "Angptl3", "gene_names_refseq": "Angptl3", "protein_names_uniprotkb": "Angiopoietin-related protein 3; Angiopoietin-like protein 3", "protein_names_refseq": "angiopoietin-related protein 3 isoform 1 precursor; angiopoietin-related protein 3", "tax_id": 10116, "disease": "familial hypobetalipoproteinemia 2 (Disease Ontology:DOID:0111061)", "pathway": " (R-RNO-8963889)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "33443084", "class_list": "", "function": "RNA Interference Targeting Liver Angiopoietin-Like Protein 3 Protects from Nephrotic Syndrome in a Rat Model Via Amelioration of Pathologic Hypertriglyceridemia., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004857 enzyme inhibitor activity;GO:0005178 integrin binding;GO:0008201 heparin binding;GO:0055102 lipase inhibitor activity;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005769 early endosome;GO:0005794 Golgi apparatus;GO:0009986 cell surface;GO:0030027 lamellipodium", "go_biological_process": "GO:0001525 angiogenesis;GO:0006631 fatty acid metabolic process;GO:0007165 signal transduction;GO:0008203 cholesterol metabolic process;GO:0030335 positive regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F7FHP0-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V6B5-1", "uniprot_id": [ { "id": "G3V6B5_RAT", "url": "https://www.uniprot.org/uniprot/G3V6B5", "type": "external" } ], "mass": 42881.0, "length": 380, "protein_name": "Serpin B7", "gene_name": "Serpinb7", "organism": "Rat", "refseq_name": "serpin B7", "refseq_ac": [ { "id": "NP_569088", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569088", "type": "external" } ], "gene_names_uniprotkb": "Serpinb7", "gene_names_refseq": "Megsin; Serpinb7", "protein_names_uniprotkb": "Serpin B7; Megsin", "protein_names_refseq": "serine (or cysteine) peptidase inhibitor, clade B, member 7; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 7; serine (or cysteine) proteinase inhibitor, clade B, member 7; serpin B7; serpin peptidase inhibitor, clade B (ovalbumin), member 7", "tax_id": 10116, "disease": "familial encephalopathy with neuroserpin inclusion bodies (Disease Ontology:DOID:0050831); Nagashima-type palmoplantar keratosis (Disease Ontology:DOID:0070555); nephritis (Disease Ontology:DOID:10952); alpha 1-antitrypsin deficiency (Disease Ontology:DOID:13372); IgA glomerulonephritis (Disease Ontology:DOID:2986)", "pathway": " (rno:117092)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "18580857;21945418", "class_list": "", "function": "High glucose per se induces megsin expression both in vivo in a model of type II diabetic nephropathy and in vitro in cultured mesangial cells, in which it also inhibits total MMP-2 and MMP-9 activities and plasmin enzymatic activity., [RefSeq, PubMed]; Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin., [UniProtKB, UniProtKB]; Over-expression of megsin induced incorporation of [(3)H]thymidine in mesangial cells and PDGF-BB, TGF-beta1 upregulation, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm", "go_biological_process": "GO:0072126 positive regulation of glomerular mesangial cell proliferation;GO:0032914 positive regulation of transforming growth factor beta1 production;GO:0032967 positive regulation of collagen biosynthetic process;GO:0090362 positive regulation of platelet-derived growth factor production", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "G3V6B5-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V6F9-1", "uniprot_id": [ { "id": "G3V6F9_RAT", "url": "https://www.uniprot.org/uniprot/G3V6F9", "type": "external" } ], "mass": 13597.0, "length": 129, "protein_name": "Tumor necrosis factor receptor superfamily member 12A", "gene_name": "Tnfrsf12a", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Tnfrsf12a", "gene_names_refseq": "", "protein_names_uniprotkb": "Tumor necrosis factor receptor superfamily member 12A; Fibroblast growth factor-inducible immediate-early response protein 14; Tweak-receptor", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-5668541); (R-RNO-5676594)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0001726 ruffle", "go_biological_process": "GO:2001238 positive regulation of extrinsic apoptotic signaling pathway;GO:0061041 regulation of wound healing;GO:0007155 cell adhesion;GO:0043065 positive regulation of apoptotic process;GO:0032967 positive regulation of collagen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "G3V6F9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V6G0-1", "uniprot_id": [ { "id": "G3V6G0_RAT", "url": "https://www.uniprot.org/uniprot/G3V6G0", "type": "external" } ], "mass": 35437.0, "length": 315, "protein_name": "Olfactory receptor", "gene_name": "Or1ad6", "organism": "Rat", "refseq_name": "olfactory receptor Olr1404", "refseq_ac": [ { "id": "NP_001000787", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000787", "type": "external" } ], "gene_names_uniprotkb": "Or1ad6", "gene_names_refseq": "Olr1404; Or1ad6; tpcr10", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1404; olfactory receptor Olr1404; olfactory receptor gene Olr1404", "tax_id": 10116, "disease": "", "pathway": " (rno:405065)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "G3V6G0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V6L1-1", "uniprot_id": [ { "id": "G3V6L1_RAT", "url": "https://www.uniprot.org/uniprot/G3V6L1", "type": "external" } ], "mass": 79105.0, "length": 710, "protein_name": "Frizzled-6", "gene_name": "Fzd6", "organism": "Rat", "refseq_name": "frizzled-6 precursor", "refseq_ac": [ { "id": "NP_001124008", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001124008", "type": "external" } ], "gene_names_uniprotkb": "Fzd6", "gene_names_refseq": "Fzd6", "protein_names_uniprotkb": "Frizzled-6", "protein_names_refseq": "frizzled family receptor 6; frizzled-6 precursor; frizzled-6", "tax_id": 10116, "disease": "nonsyndromic congenital nail disorder 1 (Disease Ontology:DOID:0080079)", "pathway": " (rno:282581); (R-RNO-4086398); (R-RNO-4086400); (R-RNO-4641263)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "38710294", "class_list": "", "function": "Fengshi Liuhe Decoction treatment for rheumatoid arthritis via the Fzd6/NF-kappaB signaling axis., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0031625 ubiquitin protein ligase binding;GO:0017147 Wnt-protein binding;GO:0042813 Wnt receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0045177 apical part of cell;GO:0005789 endoplasmic reticulum membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0042472 inner ear morphogenesis;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0030168 platelet activation;GO:0001843 neural tube closure", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "G3V6L1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V6M8-1", "uniprot_id": [ { "id": "G3V6M8_RAT", "url": "https://www.uniprot.org/uniprot/G3V6M8", "type": "external" } ], "mass": 37562.0, "length": 330, "protein_name": "Nucleoporin Nup37", "gene_name": "Nup37", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Nup37", "gene_names_refseq": "", "protein_names_uniprotkb": "Nucleoporin Nup37; Nup107-160 subcomplex subunit Nup37", "protein_names_refseq": "", "tax_id": 10116, "disease": "primary autosomal recessive microcephaly 24 (Disease Ontology:DOID:0051035)", "pathway": " (rno:299706); (R-RNO-141430); (R-RNO-141444); (R-RNO-159227); (R-RNO-159230); (R-RNO-159231); (R-RNO-159236); (R-RNO-170822); (R-RNO-1855170); (R-RNO-1855196); (R-RNO-1855229); (R-RNO-191859); (R-RNO-2467813); (R-RNO-2500257); (R-RNO-3108214); (R-RNO-3232142); (R-RNO-3301854); (R-RNO-3371453); (R-RNO-4085377); (R-RNO-4551638); (R-RNO-4570464); (R-RNO-4615885); (R-RNO-5663220); (R-RNO-68877); (R-RNO-9615933); (R-RNO-9648025)", "pathway_count": 26, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0005635 nuclear envelope;GO:0000776 kinetochore;GO:0005654 nucleoplasm", "go_biological_process": "GO:0007059 chromosome segregation;GO:0015031 protein transport;GO:0051301 cell division;GO:0051028 mRNA transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "G3V6M8-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V6U3-1", "uniprot_id": [ { "id": "G3V6U3_RAT", "url": "https://www.uniprot.org/uniprot/G3V6U3", "type": "external" } ], "mass": 47319.0, "length": 415, "protein_name": "Alpha-1,3/1,6-mannosyltransferase ALG2", "gene_name": "Alg2", "organism": "Rat", "refseq_name": "alpha-1,3/1,6-mannosyltransferase ALG2", "refseq_ac": [ { "id": "NP_001094180", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094180", "type": "external" } ], "gene_names_uniprotkb": "Alg2", "gene_names_refseq": "Alg2", "protein_names_uniprotkb": "Alpha-1,3/1,6-mannosyltransferase ALG2; 2.4.1.132; 2.4.1.257; GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase", "protein_names_refseq": "alpha-1,3-mannosyltransferase ALG2; alpha-1,3/1,6-mannosyltransferase ALG2; asparagine-linked glycosylation 2 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase); asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog", "tax_id": 10116, "disease": "congenital disorder of glycosylation Ii (Disease Ontology:DOID:0080561); congenital myasthenic syndrome 14 (Disease Ontology:DOID:0110669)", "pathway": " (rno:313231); (R-RNO-446193)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.4.1.132", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.132", "type": "external" }, { "id": "2.4.1.257", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.257", "type": "external" } ], "go_molecular_function": "GO:0000033 alpha-1,3-mannosyltransferase activity;GO:0004378 GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity;GO:0102704 GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity", "go_cellular_component": "GO:0098554 cytoplasmic side of endoplasmic reticulum membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0006488 dolichol-linked oligosaccharide biosynthetic process;GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 13365, "hit_score": 0.4, "record_id": "G3V6U3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V6W6-1", "uniprot_id": [ { "id": "G3V6W6_RAT", "url": "https://www.uniprot.org/uniprot/G3V6W6", "type": "external" } ], "mass": 45797.0, "length": 403, "protein_name": "26S proteasome regulatory subunit 10B", "gene_name": "Psmc6", "organism": "Rat", "refseq_name": "26S proteasome regulatory subunit 10B", "refseq_ac": [ { "id": "NP_001093979", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093979", "type": "external" } ], "gene_names_uniprotkb": "Psmc6; LOC100365869", "gene_names_refseq": "Psmc6", "protein_names_uniprotkb": "26S proteasome regulatory subunit 10B; 26S proteasome AAA-ATPase subunit RPT4; Proteasome 26S subunit ATPase 6; Proteasome subunit p42", "protein_names_refseq": "26S protease regulatory subunit 10B; 26S proteasome regulatory subunit 10B; proteasome (prosome, macropain) 26S subunit, ATPase, 6-like", "tax_id": 10116, "disease": "fetal alcohol spectrum disorder (Disease Ontology:DOID:0050696)", "pathway": " (rno:289990)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29398115", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0031597 cytosolic proteasome complex;GO:0022624 proteasome accessory complex;GO:0005634 nucleus;GO:0008021 synaptic vesicle;GO:0000502 proteasome complex", "go_biological_process": "GO:0010498 proteasomal protein catabolic process;GO:0090261 positive regulation of inclusion body assembly;GO:2000311 regulation of AMPA receptor activity", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "G3V6W6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V723-1", "uniprot_id": [ { "id": "G3V723_RAT", "url": "https://www.uniprot.org/uniprot/G3V723", "type": "external" } ], "mass": 86334.0, "length": 749, "protein_name": "Phosphate regulating endopeptidase X-linked", "gene_name": "Phex", "organism": "Rat", "refseq_name": "phosphate-regulating neutral endopeptidase PHEX", "refseq_ac": [ { "id": "NP_037136", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_037136", "type": "external" } ], "gene_names_uniprotkb": "Phex", "gene_names_refseq": "PEX; Phex", "protein_names_uniprotkb": "Phosphate regulating endopeptidase X-linked", "protein_names_refseq": "Phosphate regulating neutral endopeptidase on the X chromosome (X-linked hypophosphatemia XLH); metalloendopeptidase homolog PEX-like; metalloendopeptidase homolog PEX; phosphate regulating endopeptidase homolog, X-linked; phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets); phosphate-regulating neutral endopeptidase PHEX; phosphate-regulating neutral endopeptidase", "tax_id": 10116, "disease": "X-linked hypophosphatemic rickets (Disease Ontology:DOID:0050445); heart conduction disease (Disease Ontology:DOID:10273); kidney failure (Disease Ontology:DOID:1074); otitis media (Disease Ontology:DOID:10754)", "pathway": " (rno:25512)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "38116308", "class_list": "", "function": "The contribution of a novel PHEX gene mutation to X-linked hypophosphatemic rickets: a case report and an analysis of the gene mutation dosage effect in a rat model. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:1904383 response to sodium phosphate;GO:0006508 proteolysis;GO:0016485 protein processing;GO:0030324 lung development;GO:0042476 odontogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "G3V723-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V7L4-1", "uniprot_id": [ { "id": "G3V7L4_RAT", "url": "https://www.uniprot.org/uniprot/G3V7L4", "type": "external" } ], "mass": 90091.0, "length": 830, "protein_name": "Cadherin-16", "gene_name": "Cdh16", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Cdh16", "gene_names_refseq": "", "protein_names_uniprotkb": "Cadherin-16; Kidney-specific cadherin", "protein_names_refseq": "", "tax_id": 10116, "disease": "thyroid cancer (Disease Ontology:DOID:1781)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0098609 cell-cell adhesion;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "G3V7L4-1", "record_type": "protein", "filter_code": "0000000.0000110.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V7P6-1", "uniprot_id": [ { "id": "G3V7P6_RAT", "url": "https://www.uniprot.org/uniprot/G3V7P6", "type": "external" } ], "mass": 24159.0, "length": 218, "protein_name": "U8 snoRNA-decapping enzyme", "gene_name": "Nudt16", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Nudt16", "gene_names_refseq": "", "protein_names_uniprotkb": "U8 snoRNA-decapping enzyme; 3.6.1.62; 3.6.1.64; IDP phosphatase; Inosine diphosphate phosphatase; Nucleoside diphosphate-linked moiety X motif 16; m7GpppN-mRNA hydrolase", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-2393930)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.1.62", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.62", "type": "external" }, { "id": "3.6.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.9", "type": "external" }, { "id": "3.6.1.68", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.68", "type": "external" }, { "id": "3.6.1.76", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.76", "type": "external" }, { "id": "3.6.1.64", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.64", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.1.59", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.59", "type": "external" }, { "id": "3.6.1.52", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.52", "type": "external" }, { "id": "3.6.1.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.10", "type": "external" }, { "id": "3.6.1.61", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.61", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.1.77", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.77", "type": "external" }, { "id": "3.6.1.6", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.6", "type": "external" }, { "id": "3.6.1.17", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.17", "type": "external" } ], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0003729 mRNA binding;GO:0030145 manganese ion binding;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006402 mRNA catabolic process;GO:0051276 chromosome organization;GO:0016077 sno(s)RNA catabolic process;GO:0035863 dITP catabolic process;GO:0090068 positive regulation of cell cycle process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "G3V7P6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V7W0-1", "uniprot_id": [ { "id": "G3V7W0_RAT", "url": "https://www.uniprot.org/uniprot/G3V7W0", "type": "external" } ], "mass": 62694.0, "length": 645, "protein_name": "Zinc finger protein 503", "gene_name": "Zfp503", "organism": "Rat", "refseq_name": "zinc finger protein 503", "refseq_ac": [ { "id": "NP_001100720", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100720", "type": "external" } ], "gene_names_uniprotkb": "Zfp503", "gene_names_refseq": "Nolz-1; 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3.6.5.2", "protein_names_refseq": "", "tax_id": 10116, "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861)", "pathway": " (rno:361208)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB24 is an atypical RAB protein that presents low GTPase activity and thereby exists predominantly in the GTP-bound active state. RAB24 is required for the clearance of late autophagic vacuoles under basal conditions. It is not needed for starvation-induced autophagy. Involved in the modulation of meiotic apparatus assembly and meiotic progression during oocyte maturation, possibly through regulation of kinetochore-microtubule interaction., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.6.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.1", "type": "external" }, { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "3.6.5.3", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.3", "type": "external" }, { "id": "2.3.2.27", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.27", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "3.6.5.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.5", "type": "external" }, { "id": "3.6.1.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.5", "type": "external" }, { "id": "3.6.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.-", "type": "external" }, { "id": "3.6.5.4", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.4", "type": "external" } ], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0005737 cytoplasm;GO:0005819 spindle;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0008608 attachment of spindle microtubules to kinetochore;GO:0006914 autophagy;GO:0001556 oocyte maturation;GO:0140013 meiotic nuclear division", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MKB0-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A6K5-1", "uniprot_id": [ { "id": "D4A6K5_RAT", "url": "https://www.uniprot.org/uniprot/D4A6K5", "type": "external" } ], "mass": 70099.0, "length": 630, "protein_name": "Interleukin-27 receptor subunit alpha", "gene_name": "Il27ra", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Il27ra", "gene_names_refseq": "", "protein_names_uniprotkb": "Interleukin-27 receptor subunit alpha; Type I T-cell cytokine receptor", "protein_names_refseq": "", "tax_id": 10116, "disease": "systemic scleroderma (Disease Ontology:DOID:418)", "pathway": " (rno:288905)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0045509 interleukin-27 receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:2000317 negative regulation of T-helper 17 type immune response;GO:0032700 negative regulation of interleukin-17 production;GO:0048302 regulation of isotype switching to IgG isotypes;GO:0050830 defense response to Gram-positive bacterium;GO:0032715 negative regulation of interleukin-6 production", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A6K5-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0R713-1", "uniprot_id": [ { "id": "M0R713_RAT", "url": "https://www.uniprot.org/uniprot/M0R713", "type": "external" } ], "mass": 73777.0, "length": 625, "protein_name": "Zinc finger protein 955A", "gene_name": "Zfp955a", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Zfp955a", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 955A", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-212436)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R713-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M9D6-1", "uniprot_id": [ { "id": "F1M9D6_RAT", "url": "https://www.uniprot.org/uniprot/F1M9D6", "type": "external" } ], "mass": 88008.0, "length": 755, "protein_name": "Signal transducer and activator of transcription", "gene_name": "Stat1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Stat1; Stat4", "gene_names_refseq": "", "protein_names_uniprotkb": "Signal transducer and activator of transcription", "protein_names_refseq": "", "tax_id": 10116, "disease": "chromosome 1q21.1 deletion syndrome (Disease Ontology:DOID:0060411); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); trimethylaminuria (Disease Ontology:DOID:0080361); polymyositis (Disease Ontology:DOID:0080745); disabling pansclerotic morphea (Disease Ontology:DOID:0081373); immunodeficiency 31B (Disease Ontology:DOID:0111944); immunodeficiency 31A (Disease Ontology:DOID:0111945); immunodeficiency 31C (Disease Ontology:DOID:0111946); dermatomyositis (Disease Ontology:DOID:10223); hypertension (Disease Ontology:DOID:10763); primary biliary cholangitis (Disease Ontology:DOID:12236); Vogt-Koyanagi-Harada disease (Disease Ontology:DOID:12297); Sjogren's syndrome (Disease Ontology:DOID:12894); Behcet's disease (Disease Ontology:DOID:13241); limited scleroderma (Disease Ontology:DOID:1577); diffuse scleroderma (Disease Ontology:DOID:1580); breast cancer (Disease Ontology:DOID:1612); hepatitis C (Disease Ontology:DOID:1883); viral hepatitis (Disease Ontology:DOID:1884); rectum adenocarcinoma (Disease Ontology:DOID:1996); autoimmune hepatitis (Disease Ontology:DOID:2048); nephroblastoma (Disease Ontology:DOID:2154); colon adenocarcinoma (Disease Ontology:DOID:234); prostate adenocarcinoma (Disease Ontology:DOID:2526); asthma (Disease Ontology:DOID:2841); severe acute respiratory syndrome (Disease Ontology:DOID:2945); IgA glomerulonephritis (Disease Ontology:DOID:2986); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); angiomyolipoma (Disease Ontology:DOID:3314); lymphangioleiomyomatosis (Disease Ontology:DOID:3319); breast carcinoma (Disease Ontology:DOID:3459); gastric adenocarcinoma (Disease Ontology:DOID:3717); pulmonary fibrosis (Disease Ontology:DOID:3770); tuberculosis (Disease Ontology:DOID:399); systemic scleroderma (Disease Ontology:DOID:418); inherited metabolic disorder (Disease Ontology:DOID:655); hepatocellular carcinoma (Disease Ontology:DOID:684); Sezary's disease (Disease Ontology:DOID:8541); cholesteatoma (Disease Ontology:DOID:869); genital herpes (Disease Ontology:DOID:8704); psoriasis (Disease Ontology:DOID:8893); psoriatic arthritis (Disease Ontology:DOID:9008); systemic lupus erythematosus (Disease Ontology:DOID:9074); obesity (Disease Ontology:DOID:9970)", "pathway": " (R-RNO-1059683); (R-RNO-1169408); (R-RNO-1433557); (R-RNO-186763); (R-RNO-6785807); (R-RNO-877300); (R-RNO-877312); (R-RNO-8854691); (R-RNO-8984722); (R-RNO-8985947); (R-RNO-9020956); (R-RNO-9020958); (R-RNO-909733); (R-RNO-912694); (R-RNO-9833482); (R-RNO-9860927)", "pathway_count": 16, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 44, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0019899 enzyme binding;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0030424 axon", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0071345 cellular response to cytokine stimulus;GO:0019221 cytokine-mediated signaling pathway;GO:0045063 T-helper 1 cell differentiation;GO:0070106 interleukin-27-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1M9D6-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1M816-1", "uniprot_id": [ { "id": "F1M816_RAT", "url": "https://www.uniprot.org/uniprot/F1M816", "type": "external" } ], "mass": 410017.0, "length": 3744, "protein_name": "Msx2-interacting protein", "gene_name": "Spen", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Spen; 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Ptpn13; ptp", "protein_names_uniprotkb": "Tyrosine-protein phosphatase non-receptor type 13; 3.1.3.48", "protein_names_refseq": "tyrosine-protein phosphatase non-receptor type 13 isoform X2", "tax_id": 10116, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); breast cancer (Disease Ontology:DOID:1612); colon cancer (Disease Ontology:DOID:219); transient cerebral ischemia (Disease Ontology:DOID:224); gastric adenocarcinoma (Disease Ontology:DOID:3717); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung adenocarcinoma (Disease Ontology:DOID:3910); lung large cell carcinoma (Disease Ontology:DOID:4556); head and neck squamous cell carcinoma (Disease Ontology:DOID:5520); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (R-RNO-1660499); (R-RNO-9696264); (R-RNO-9696270); (R-RNO-9696273)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "16641100;22673903", "class_list": "", "function": "Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Tyrosine phosphatase which negatively regulates FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.1.3.48", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "3.1.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.2", "type": "external" }, { "id": "3.1.3.21", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.21", "type": "external" }, { "id": "3.1.3.18", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.18", "type": "external" }, { "id": "3.1.3.67", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.67", "type": "external" }, { "id": "3.1.3.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.-", "type": "external" }, { "id": "2.7.3.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.3.2", "type": "external" }, { "id": "3.1.3.27", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27", "type": "external" }, { "id": "3.1.3.5", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.5", "type": "external" }, { "id": "1.2.1.3", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.3", "type": "external" }, { "id": "1.2.1.94", "url": "https://www.rhea-db.org/rhea/?query=ec:1.2.1.94", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "3.6.4.13", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.4.17.22", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.17.22", "type": "external" } ], "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity;GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0030027 lamellipodium;GO:0005886 plasma membrane", "go_biological_process": "GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0035335 peptidyl-tyrosine dephosphorylation;GO:0001933 negative regulation of protein phosphorylation;GO:0097237 cellular response to toxic substance;GO:0006470 protein dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "G3V9S3-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZJR1-1", "uniprot_id": [ { "id": "D3ZJR1_RAT", "url": "https://www.uniprot.org/uniprot/D3ZJR1", "type": "external" } ], "mass": 99714.0, "length": 911, "protein_name": "Epidermal growth factor receptor substrate 15-like 1", "gene_name": "Eps15l1", "organism": "Rat", "refseq_name": "epidermal growth factor receptor substrate 15-like 1 isoform 2", "refseq_ac": [ { "id": "NP_001423803", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001423803", "type": "external" } ], "gene_names_uniprotkb": "Eps15l1", "gene_names_refseq": "Eps15l1", "protein_names_uniprotkb": "Epidermal growth factor receptor substrate 15-like 1; Eps15-related protein", "protein_names_refseq": "epidermal growth factor receptor substrate 15-like 1 isoform 2; epidermal growth factor receptor substrate 15-like 1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-182971); (R-RNO-8856825); (R-RNO-8856828)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4QQT7", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0098793 presynapse;GO:0030132 clathrin coat of coated pit;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0048488 synaptic vesicle endocytosis;GO:0006897 endocytosis;GO:0016197 endosomal transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZJR1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZY74-1", "uniprot_id": [ { "id": "D3ZY74_RAT", "url": "https://www.uniprot.org/uniprot/D3ZY74", "type": "external" } ], "mass": 20190.0, "length": 178, "protein_name": "FANCD2 opposite strand", "gene_name": "Fancd2os", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Fancd2os; RGD1565997", "gene_names_refseq": "", "protein_names_uniprotkb": "FANCD2 opposite strand", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:500294)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:2000225 negative regulation of testosterone biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZY74-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZPP9-1", "uniprot_id": [ { "id": "D3ZPP9_RAT", "url": "https://www.uniprot.org/uniprot/D3ZPP9", "type": "external" } ], "mass": 21029.0, "length": 183, "protein_name": "Caspase recruitment domain-containing protein 19", "gene_name": "Card19", "organism": "Rat", "refseq_name": "caspase recruitment domain-containing protein 19 isoform 1", "refseq_ac": [ { "id": "NP_001406079", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001406079", "type": "external" } ], "gene_names_uniprotkb": "Card19; RGD1306058", "gene_names_refseq": "Bincard; Card19; RGD1306058", "protein_names_uniprotkb": "Caspase recruitment domain-containing protein 19; Bcl10-interacting CARD protein", "protein_names_refseq": "Bcl10-interacting protein with Card; bcl10-interacting CARD protein; caspase recruitment domain-containing protein 19 isoform 1; caspase recruitment domain-containing protein 19", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0031966 mitochondrial membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0030163 protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZPP9-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K7L4-1", "uniprot_id": [ { "id": "A0A0G2K7L4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K7L4", "type": "external" } ], "mass": 50290.0, "length": 463, "protein_name": "Inositol-tetrakisphosphate 1-kinase", "gene_name": "Itpk1", "organism": "Rat", "refseq_name": "inositol-tetrakisphosphate 1-kinase isoform X1", "refseq_ac": [ { "id": "XP_017449793", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017449793", "type": "external" } ], "gene_names_uniprotkb": "Itpk1", "gene_names_refseq": "Itpk1", "protein_names_uniprotkb": "Inositol-tetrakisphosphate 1-kinase", "protein_names_refseq": "inositol-tetrakisphosphate 1-kinase isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:500709); (R-RNO-1855167); (R-RNO-1855204); (R-RNO-983231)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.1.134", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.134", "type": "external" }, { "id": "2.7.1.159", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.159", "type": "external" } ], "go_molecular_function": "GO:0047325 inositol-3,4,5,6-tetrakisphosphate 1-kinase activity;GO:0052725 inositol-1,3,4-trisphosphate 6-kinase activity;GO:0052726 inositol-1,3,4-trisphosphate 5-kinase activity;GO:0000287 magnesium ion binding;GO:0005524 ATP binding", "go_cellular_component": "GO:0016324 apical plasma membrane", "go_biological_process": "GO:0021915 neural tube development;GO:0070266 necroptotic process;GO:0032957 inositol trisphosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K7L4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K1L0-1", "uniprot_id": [ { "id": "A0A0G2K1L0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K1L0", "type": "external" } ], "mass": 231674.0, "length": 2110, "protein_name": "Tenascin", "gene_name": "Tnc", "organism": "Rat", "refseq_name": "tenascin isoform X3", "refseq_ac": [ { "id": "XP_008761978", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008761978", "type": "external" } ], "gene_names_uniprotkb": "Tnc", "gene_names_refseq": "Tnc", "protein_names_uniprotkb": "Tenascin; Hexabrachion; Tenascin-C", "protein_names_refseq": "tenascin isoform X3", "tax_id": 10116, "disease": "polycystic kidney disease (Disease Ontology:DOID:0080322); autosomal dominant nonsyndromic deafness 56 (Disease Ontology:DOID:0110581); asbestosis (Disease Ontology:DOID:10320); pleural tuberculosis (Disease Ontology:DOID:106); allergic conjunctivitis (Disease Ontology:DOID:11204); intracranial vasospasm (Disease Ontology:DOID:13100); lung cancer (Disease Ontology:DOID:1324); pulmonary sarcoidosis (Disease Ontology:DOID:13406); asthma (Disease Ontology:DOID:2841); glioblastoma (Disease Ontology:DOID:3068); high grade glioma (Disease Ontology:DOID:3070); pleural empyema (Disease Ontology:DOID:3798); cholangiocarcinoma (Disease Ontology:DOID:4947); pneumonia (Disease Ontology:DOID:552); myocardial infarction (Disease Ontology:DOID:5844); pulmonary hypertension (Disease Ontology:DOID:6432); extrinsic allergic alveolitis (Disease Ontology:DOID:841)", "pathway": " (rno:116640); (R-RNO-216083); (R-RNO-3000178); (R-RNO-381426); (R-RNO-8957275)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "28657654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 17, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0045545 syndecan binding", "go_cellular_component": "GO:0098966 perisynaptic extracellular matrix;GO:0005615 extracellular space;GO:0005604 basement membrane;GO:0005614 interstitial matrix;GO:0098978 glutamatergic synapse", "go_biological_process": "GO:0007155 cell adhesion;GO:0009611 response to wounding;GO:0030155 regulation of cell adhesion;GO:0001558 regulation of cell growth;GO:0050727 regulation of inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2K1L0-1", "record_type": "protein", "filter_code": "0000000.1000111.010000.000000000000001000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V6T1-1", "uniprot_id": [ { "id": "G3V6T1_RAT", "url": "https://www.uniprot.org/uniprot/G3V6T1", "type": "external" } ], "mass": 138656.0, "length": 1227, "protein_name": "Coatomer subunit alpha", "gene_name": "Copa", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Copa", "gene_names_refseq": "", "protein_names_uniprotkb": "Coatomer subunit alpha", "protein_names_refseq": "", "tax_id": 10116, "disease": "autoimmune interstitial lung, joint, and kidney disease (Disease Ontology:DOID:0081242)", "pathway": " (rno:304978); (R-RNO-6807878); (R-RNO-6811434)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Xenin stimulates exocrine pancreatic secretion. It inhibits pentagastrin-stimulated secretion of acid, to induce exocrine pancreatic secretion and to affect small and large intestinal motility. In the gut, xenin interacts with the neurotensin receptor., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity;GO:0003729 mRNA binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0030126 COPI vesicle coat;GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006891 intra-Golgi vesicle-mediated transport;GO:0099612 protein localization to axon", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "G3V6T1-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JUH4-1", "uniprot_id": [ { "id": "A0A0G2JUH4_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JUH4", "type": "external" } ], "mass": 57448.0, "length": 525, "protein_name": "Bifunctional polynucleotide phosphatase/kinase", "gene_name": "Pnkp", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Pnkp", "gene_names_refseq": "", "protein_names_uniprotkb": "Bifunctional polynucleotide phosphatase/kinase; 2.7.1.78; 3.1.3.32; DNA 5'-kinase/3'-phosphatase; Polynucleotide kinase-3'-phosphatase", "protein_names_refseq": "", "tax_id": 10116, "disease": "microcephaly, seizures, and developmental delay (Disease Ontology:DOID:0080457); ataxia-oculomotor apraxia 4 (Disease Ontology:DOID:0081383); Charcot-Marie-Tooth disease type 2B2 (Disease Ontology:DOID:0110179)", "pathway": " (R-RNO-5649702)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "6.5.1.1", "url": "https://www.rhea-db.org/rhea/?query=ec:6.5.1.1", "type": "external" }, { "id": "2.7.1.78", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.78", "type": "external" }, { "id": "3.1.3.32", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.32", "type": "external" }, { "id": "4.2.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.18", "type": "external" }, { "id": "2.7.7.7", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.7", "type": "external" }, { "id": "4.2.99.-", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.99.-", "type": "external" } ], "go_molecular_function": "GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity;GO:0046403 polynucleotide 3'-phosphatase activity;GO:1990756 ubiquitin-like ligase-substrate adaptor activity;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0019005 SCF ubiquitin ligase complex;GO:0035861 site of double-strand break", "go_biological_process": "GO:0006281 DNA repair;GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining;GO:0006979 response to oxidative stress;GO:0006974 DNA damage response;GO:0006303 double-strand break repair via nonhomologous end joining", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JUH4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q66HB1-1", "uniprot_id": [ { "id": "Q66HB1_RAT", "url": "https://www.uniprot.org/uniprot/Q66HB1", "type": "external" } ], "mass": 34951.0, "length": 318, "protein_name": "TATA box binding protein", "gene_name": "Tbp", "organism": "Rat", "refseq_name": "TATA-box-binding protein isoform 1", "refseq_ac": [ { "id": "NP_001004198", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004198", "type": "external" } ], "gene_names_uniprotkb": "Tbp", "gene_names_refseq": "TFIID; Tbp", "protein_names_uniprotkb": "TATA box binding protein", "protein_names_refseq": "TATA-box-binding protein isoform 1", "tax_id": 10116, "disease": "sleep apnea (Disease Ontology:DOID:0050847); spinocerebellar ataxia 17 (Disease Ontology:DOID:0050967); late onset Parkinson's disease (Disease Ontology:DOID:0060892); Alzheimer's disease (Disease Ontology:DOID:10652); Huntington's disease (Disease Ontology:DOID:12858); neurodegenerative disease (Disease Ontology:DOID:1289); schizophrenia (Disease Ontology:DOID:5419); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (rno:117526); (R-RNO-5250924); (R-RNO-674695); (R-RNO-6804756); (R-RNO-6807505); (R-RNO-73762); (R-RNO-73772); (R-RNO-73776); (R-RNO-73779); (R-RNO-73863); (R-RNO-75953); (R-RNO-76042); (R-RNO-76061); (R-RNO-76066); (R-RNO-76071); (R-RNO-9018519)", "pathway_count": 16, "publication_count": 1, "publication_id_list": "28134789", "class_list": "", "function": "Mrpl10 and Tbp might be used as suitable reference genes for sciatic nerve stump and dorsal root ganglions, respectively. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0001093 TFIIB-class transcription factor binding;GO:0019899 enzyme binding;GO:0017162 aryl hydrocarbon receptor binding;GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005668 RNA polymerase transcription factor SL1 complex;GO:0000791 euchromatin;GO:0005672 transcription factor TFIIA complex;GO:0005669 transcription factor TFIID complex", "go_biological_process": "GO:0006352 DNA-templated transcription initiation;GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0045945 positive regulation of transcription by RNA polymerase III;GO:0042789 mRNA transcription by RNA polymerase II;GO:0051123 RNA polymerase II preinitiation complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q66HB1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JW29-1", "uniprot_id": [ { "id": "A0A0G2JW29_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JW29", "type": "external" } ], "mass": 82331.0, "length": 747, "protein_name": "alpha-1,2-Mannosidase", "gene_name": "Man1a1", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Man1a1", "gene_names_refseq": "", "protein_names_uniprotkb": "alpha-1,2-Mannosidase; 3.2.1.-", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:294410); (R-RNO-964827)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.2.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.-", "type": "external" }, { "id": "3.2.1.113", "url": "https://www.rhea-db.org/rhea/?query=ec:3.2.1.113", "type": "external" } ], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0031410 cytoplasmic vesicle;GO:0005793 endoplasmic reticulum-Golgi intermediate compartment;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0036503 ERAD pathway;GO:0045047 protein targeting to ER;GO:1904382 mannose trimming involved in glycoprotein ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JW29-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K6R0-1", "uniprot_id": [ { "id": "A0A0G2K6R0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K6R0", "type": "external" } ], "mass": 198655.0, "length": 1875, "protein_name": "Trinucleotide repeat containing adaptor 6B", "gene_name": "Tnrc6b", "organism": "Rat", "refseq_name": "trinucleotide repeat-containing gene 6B protein isoform X1", "refseq_ac": [ { "id": "XP_063119031", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_063119031", "type": "external" } ], "gene_names_uniprotkb": "Tnrc6b", "gene_names_refseq": "Cbl27; Tnrc6b", "protein_names_uniprotkb": "Trinucleotide repeat containing adaptor 6B", "protein_names_refseq": "trinucleotide repeat-containing gene 6B protein isoform X1", "tax_id": 10116, "disease": "uterine fibroid (Disease Ontology:DOID:13223); subserous uterine fibroid (Disease Ontology:DOID:13560)", "pathway": " (R-RNO-426496)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005654 nucleoplasm;GO:0000932 P-body", "go_biological_process": "GO:0006417 regulation of translation;GO:0031047 regulatory ncRNA-mediated gene silencing;GO:0035278 miRNA-mediated gene silencing by inhibition of translation;GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K6R0-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JYE0-1", "uniprot_id": [ { "id": "A0A0G2JYE0_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JYE0", "type": "external" } ], "mass": 115342.0, "length": 1096, "protein_name": "Ataxin 2-like", "gene_name": "Atxn2l", "organism": "Rat", "refseq_name": "ataxin-2-like protein isoform X3", "refseq_ac": [ { "id": "XP_006230365", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006230365", "type": "external" } ], "gene_names_uniprotkb": "Atxn2l", "gene_names_refseq": "Atxn2l; RGD1565868", "protein_names_uniprotkb": "Ataxin 2-like", "protein_names_refseq": "ataxin-2-like protein isoform X3", "tax_id": 10116, "disease": "spinocerebellar ataxia 2 (Disease Ontology:DOID:0050955); chromosome 16p11.2 deletion syndrome, 593-kb (Disease Ontology:DOID:0070515); autosomal dominant cerebellar ataxia (Disease Ontology:DOID:1441)", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "22673903;38843836", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane;GO:0016607 nuclear speck;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0016071 mRNA metabolic process;GO:0034063 stress granule assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0G2JYE0-1", "record_type": "protein", "filter_code": "0000000.0000110.010000.000000000000001000.0100000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D3ZMX5-1", "uniprot_id": [ { "id": "D3ZMX5_RAT", "url": "https://www.uniprot.org/uniprot/D3ZMX5", "type": "external" } ], "mass": 90928.0, "length": 846, "protein_name": "Sterile alpha motif domain containing 11", "gene_name": "Samd11", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Samd11", "gene_names_refseq": "", "protein_names_uniprotkb": "Sterile alpha motif domain containing 11", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:102549710)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, 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"synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZMX5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "D4A7I8-1", "uniprot_id": [ { "id": "D4A7I8_RAT", "url": "https://www.uniprot.org/uniprot/D4A7I8", "type": "external" } ], "mass": 40080.0, "length": 372, "protein_name": "Formylglycine-generating enzyme", "gene_name": "Sumf1", "organism": "Rat", "refseq_name": "formylglycine-generating enzyme precursor", "refseq_ac": [ { "id": "NP_001102109", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102109", "type": "external" } ], "gene_names_uniprotkb": "Sumf1", "gene_names_refseq": "Sumf1", "protein_names_uniprotkb": "Formylglycine-generating enzyme; 1.8.3.7; C-alpha-formylglycine-generating enzyme 1; Sulfatase-modifying factor 1", "protein_names_refseq": "formylglycine-generating enzyme precursor; formylglycine-generating enzyme", "tax_id": 10116, 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"reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex;GO:0005654 nucleoplasm;GO:0140552 TEAD-YAP complex", "go_biological_process": "GO:1902459 positive regulation of stem cell population maintenance;GO:0006351 DNA-templated transcription;GO:0035329 hippo signaling;GO:0007507 heart development;GO:0030307 positive regulation of cell growth", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K2N3-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A096MKF9-1", "uniprot_id": [ { "id": "A0A096MKF9_RAT", "url": "https://www.uniprot.org/uniprot/A0A096MKF9", "type": "external" } ], "mass": 68984.0, "length": 621, "protein_name": "Complement C2", "gene_name": "C2; Cfb", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "C2; Cfb; C2; Cfb", "gene_names_refseq": "", "protein_names_uniprotkb": "Complement C2; C3/C5 convertase", "protein_names_refseq": "", "tax_id": 10116, "disease": "sinusitis (Disease Ontology:DOID:0050127); complement component 2 deficiency (Disease Ontology:DOID:0060295); lupus nephritis (Disease Ontology:DOID:0080162); atypical hemolytic-uremic syndrome (Disease Ontology:DOID:0080301); polycystic kidney disease (Disease Ontology:DOID:0080322); erythema nodosum (Disease Ontology:DOID:0080750); age related macular degeneration 14 (Disease Ontology:DOID:0110026); Alport syndrome 3A (Disease Ontology:DOID:0110032); Alport syndrome 2 (Disease Ontology:DOID:0110033); benign familial hematuria (Disease Ontology:DOID:0111365); Alzheimer's disease (Disease Ontology:DOID:10652); lepromatous leprosy (Disease Ontology:DOID:10887); sickle cell anemia (Disease Ontology:DOID:10923); membranous glomerulonephritis (Disease Ontology:DOID:10976); Alport syndrome (Disease Ontology:DOID:10983); pyelonephritis (Disease Ontology:DOID:11400); factor VIII deficiency (Disease Ontology:DOID:12134); beta thalassemia (Disease Ontology:DOID:12241); paracoccidioidomycosis (Disease Ontology:DOID:12662); Behcet's disease (Disease Ontology:DOID:13241); anterior uveitis (Disease Ontology:DOID:1407); boutonneuse fever (Disease Ontology:DOID:14095); breast cancer (Disease Ontology:DOID:1612); membranoproliferative glomerulonephritis (Disease Ontology:DOID:2920); glomerulonephritis (Disease Ontology:DOID:2921); IgA glomerulonephritis (Disease Ontology:DOID:2986); systemic scleroderma (Disease Ontology:DOID:418); macular degeneration (Disease Ontology:DOID:4448); conjunctivitis (Disease Ontology:DOID:6195); end stage renal disease (Disease Ontology:DOID:783); retinal degeneration (Disease Ontology:DOID:8466); psoriasis (Disease Ontology:DOID:8893); diabetic retinopathy (Disease Ontology:DOID:8947); autosomal dominant polycystic kidney disease (Disease Ontology:DOID:898); systemic lupus erythematosus (Disease Ontology:DOID:9074); type 1 diabetes mellitus (Disease Ontology:DOID:9744); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (rno:294257); (R-RNO-166663); (R-RNO-174577); (R-RNO-977606)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalytic component of the complement C3 and C5 convertase complexes. Following complement activation, recruited to the surface of pathogens by complement C4b opsonin to form the C3 convertase, or C3b and C4b opsonins to form the C5 convertase. As part of the C3 convertase, cleaves and activate C3 into C3a anaphylatoxin and C3b opsonin, the next components of the complement pathways. As part of the C5 convertase, cleaves and activate C5 into C5a anaphylatoxin and C5b component of the membrane attack complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Involved in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes., [UniProtKB, UniProtKB]; Precursor of the catalytic component of the C3 and C5 convertase complexes of the alternative pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. The alternative complement pathway acts as an amplification loop that enhances other complement pathways (classical, lectin and GZMK) by promoting formation of additional C3 and C5 convertases. CFB is cleaved and activated by CFD to generate Ba and Bb chains; Bb chain constituting the catalytic component of the C3 and C5 convertases., [UniProtKB, UniProtKB]; Precursor of the catalytic component of the C3 and C5 convertase complexes, which are part of the complement pathway, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Component C2 is part of the classical, lectin and GZMK complement systems., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Serine protease component of the complement C3 and C5 convertase complexes of the alternative complement pathway. Following cleavage and activation by factor D (CFD), forms the C3 convertase together with complement C3b. As part of the C3 convertase, cleaves and activates C3 into C3a anaphylatoxin and C3b opsonin, the next components of the complement pathways. When an additional complement C3b molecule binds to the C3 convertase, forms the C5 convertase, which cleaves and activates C5 into C5a anaphylatoxin and C5b component of the membrane attack complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 37, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0009986 cell surface;GO:0106139 symbiont cell surface;GO:0005615 extracellular space;GO:0098548 cytoplasmic side of Golgi membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0045087 innate immune response;GO:0006958 complement activation, classical pathway;GO:0009617 response to bacterium;GO:0006956 complement activation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MKF9-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1LXX1-1", "uniprot_id": [ { "id": "F1LXX1_RAT", "url": "https://www.uniprot.org/uniprot/F1LXX1", "type": "external" } ], "mass": 39076.0, "length": 353, "protein_name": "Sperm-tail PG-rich repeat containing 4", "gene_name": "Stpg4", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Stpg4; LOC681766", "gene_names_refseq": "", "protein_names_uniprotkb": "Sperm-tail PG-rich repeat containing 4", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:681766)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0001939 female pronucleus;GO:0001940 male pronucleus;GO:0042585 germinal vesicle", "go_biological_process": "GO:0044727 epigenetic programing of male pronucleus;GO:0072529 pyrimidine-containing compound catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LXX1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V6D5-1", "uniprot_id": [ { "id": "G3V6D5_RAT", "url": "https://www.uniprot.org/uniprot/G3V6D5", "type": "external" } ], "mass": 19456.0, "length": 183, "protein_name": "VCP nuclear cofactor family member 1", "gene_name": "Vcf1", "organism": "Rat", "refseq_name": "protein VCF1", "refseq_ac": [ { "id": "NP_001030130", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030130", "type": "external" } ], "gene_names_uniprotkb": "Vcf1; Fam104a", "gene_names_refseq": "Fam104a; Vcf1", "protein_names_uniprotkb": "VCP nuclear cofactor family member 1", "protein_names_refseq": "family with sequence similarity 104, member A; protein VCF1", "tax_id": 10116, "disease": "", "pathway": " (rno:619573)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "G3V6D5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5PQK5-1", "uniprot_id": [ { "id": "Q5PQK5_RAT", "url": "https://www.uniprot.org/uniprot/Q5PQK5", "type": "external" } ], "mass": 75803.0, "length": 645, "protein_name": "Radixin", "gene_name": "Rdx", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Rdx", "gene_names_refseq": "", "protein_names_uniprotkb": "Radixin", "protein_names_refseq": "", "tax_id": 10116, "disease": "autosomal recessive nonsyndromic deafness 24 (Disease Ontology:DOID:0110482); Dubin-Johnson syndrome (Disease Ontology:DOID:12308)", "pathway": " (rno:315655); (R-RNO-437239)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0019904 protein domain specific binding;GO:0051117 ATPase binding;GO:0050839 cell adhesion molecule binding;GO:0051018 protein kinase A binding", "go_cellular_component": "GO:0051286 cell tip;GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0005925 focal adhesion;GO:0030027 lamellipodium", "go_biological_process": "GO:1902966 positive regulation of protein localization to early endosome;GO:0030033 microvillus assembly;GO:0061028 establishment of endothelial barrier;GO:1902115 regulation of organelle assembly;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q5PQK5-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6P7D7-1", "uniprot_id": [ { "id": "Q6P7D7_RAT", "url": "https://www.uniprot.org/uniprot/Q6P7D7", "type": "external" } ], "mass": 53409.0, "length": 490, "protein_name": "Transmembrane protease serine 2", "gene_name": "Tmprss2", "organism": "Rat", "refseq_name": "transmembrane protease serine 2", "refseq_ac": [ { "id": "NP_569108", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569108", "type": "external" } ], "gene_names_uniprotkb": "Tmprss2", "gene_names_refseq": "Tmprss2", "protein_names_uniprotkb": "Transmembrane protease serine 2; 3.4.21.122", "protein_names_refseq": "transmembrane protease serine 2; transmembrane protease, serine 2", "tax_id": 10116, "disease": "", "pathway": " (rno:156435)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "32940922;33660945;34684358;35000261", "class_list": "", "function": "ACE2 and TMPRSS2 immunolocalization and oral manifestations of COVID-19., [RefSeq, PubMed]; Expression of ACE2 and TMPRSS2 Proteins in the Upper and Lower Aerodigestive Tracts of Rats: Implications on COVID 19 Infections., [RefSeq, PubMed]; Obesogenic and Ketogenic Diets Distinctly Regulate the SARS-CoV-2 Entry Proteins ACE2 and TMPRSS2 and the Renin-Angiotensin System in Rat Lung and Heart Tissues. Publication Status: Online-Only, [RefSeq, PubMed]; Pulmonary, cardiac and renal distribution of ACE2, furin, TMPRSS2 and ADAM17 in rats with heart failure: Potential implication for COVID-19 disease., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0008236 serine-type peptidase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005576 extracellular region;GO:0005886 plasma membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0016540 protein autoprocessing", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q6P7D7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JTR4-1", "uniprot_id": [ { "id": "ABR_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JTR4", "type": "external" } ], "mass": 97693.0, "length": 859, "protein_name": "Active breakpoint cluster region-related protein", "gene_name": "Abr", "organism": "Rat", "refseq_name": "active breakpoint cluster region-related protein", "refseq_ac": [ { "id": "NP_001099284", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099284", "type": "external" } ], "gene_names_uniprotkb": "Abr", "gene_names_refseq": "Abr", "protein_names_uniprotkb": "Active breakpoint cluster region-related protein", "protein_names_refseq": "ABR, RhoGEF and GTPase activating protein; active BCR-related; active breakpoint cluster region-related protein; breakpoint cluster region protein-like", "tax_id": 10116, "disease": "", "pathway": " (rno:287537); (R-RNO-193648); (R-RNO-416482); (R-RNO-8980692); (R-RNO-9013026); (R-RNO-9013106); (R-RNO-9013148); (R-RNO-9013149); (R-RNO-9013404); (R-RNO-9013423)", "pathway_count": 10, "publication_count": 2, "publication_id_list": "20962234;22673903", "class_list": "", "function": "Breakpoint cluster region and ABR have novel roles in the regulation of synaptic Rac1 signaling, synaptic plasticity, and learning and memory, and that excessive Rac1 activity negatively affects synaptic and cognitive functions, [RefSeq, PubMed]; Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins. The C-terminus is a GTPase-activating protein domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. Accelerates the intrinsic rate of GTP hydrolysis of RAC1 or CDC42, leading to down-regulation of the active GTP-bound form. The central Dbl homology (DH) domain functions as guanine nucleotide exchange factor (GEF) that modulates the GTPases CDC42, RHOA and RAC1. Promotes the conversion of CDC42, RHOA and RAC1 from the GDP-bound to the GTP-bound form (By similarity). Functions as an important negative regulator of neuronal RAC1 activity (By similarity). Regulates macrophage functions such as CSF-1 directed motility and phagocytosis through the modulation of RAC1 activity (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0004674 protein serine/threonine kinase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon", "go_biological_process": "GO:0032496 response to lipopolysaccharide;GO:0035556 intracellular signal transduction;GO:0042472 inner ear morphogenesis;GO:0050885 neuromuscular process controlling balance;GO:0030336 negative regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2JTR4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JUP3-1", "uniprot_id": [ { "id": "A0A0G2JUP3_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JUP3", "type": "external" } ], "mass": 805974.0, "length": 7408, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Obscn", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Obscn", "gene_names_refseq": "", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "", "tax_id": 10116, "disease": "dilated cardiomyopathy (Disease Ontology:DOID:12930); myopathy (Disease Ontology:DOID:423)", "pathway": " (R-RNO-193648); (R-RNO-416482); (R-RNO-8980692); (R-RNO-9013406)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.1.153", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.153", "type": "external" }, { "id": "2.7.1.137", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.137", "type": "external" }, { "id": "2.7.11.24", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.24", "type": "external" }, { "id": "2.7.11.25", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25", "type": "external" }, { "id": "2.7.11.22", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" }, { "id": "2.7.4.6", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.6", "type": "external" }, { "id": "2.7.1.154", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.154", "type": "external" }, { "id": "2.7.11.38", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.38", "type": "external" }, { "id": "2.7.11.17", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.17", "type": "external" }, { "id": "2.7.11.21", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.21", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.12", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.12", "type": "external" }, { "id": "2.7.11.26", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.26", "type": "external" }, { "id": "2.7.11.34", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.1.150", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.150", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "4.1.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.32", "type": "external" }, { "id": "2.7.11.19", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.19", "type": "external" }, { "id": "2.7.2.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.2.3", "type": "external" }, { "id": "2.7.11.11", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.11", "type": "external" }, { "id": "2.7.11.31", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.31", "type": "external" }, { "id": "3.6.5.2", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2", "type": "external" }, { "id": "3.1.3.16", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16", "type": "external" }, { "id": "2.7.11.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.4", "type": "external" }, { "id": "2.3.1.48", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48", "type": "external" }, { "id": "3.1.11.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.11.-", "type": "external" }, { "id": "2.7.13.3", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.13.3", "type": "external" }, { "id": "2.7.4.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.18", "type": "external" }, { "id": "3.1.24.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.24.-", "type": "external" }, { "id": "3.4.19.12", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.19.12", "type": "external" }, { "id": "2.7.11.39", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.39", "type": "external" }, { "id": "2.4.99.18", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.99.18", "type": "external" }, { "id": "2.7.11.10", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.10", "type": "external" } ], "go_molecular_function": "GO:1902936 phosphatidylinositol bisphosphate binding;GO:0010314 phosphatidylinositol-5-phosphate binding;GO:0004672 protein kinase activity;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0014704 intercalated disc;GO:0030017 sarcomere;GO:0042383 sarcolemma", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0046777 protein autophosphorylation;GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JUP3-1", "record_type": "protein", "filter_code": "0000000.1000111.000010.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JTU1-1", "uniprot_id": [ { "id": "A0A0G2JTU1_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JTU1", "type": "external" } ], "mass": 164825.0, "length": 1474, "protein_name": "DNA excision repair protein ERCC-6", "gene_name": "Ercc6", "organism": "Rat", "refseq_name": "DNA excision repair protein ERCC-6 isoform 1", "refseq_ac": [ { "id": "NP_001423629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001423629", "type": "external" } ], "gene_names_uniprotkb": "Ercc6", "gene_names_refseq": "Ercc6", "protein_names_uniprotkb": "DNA excision repair protein ERCC-6; ATP-dependent helicase ERCC6; Cockayne syndrome protein CSB", "protein_names_refseq": "DNA excision repair protein ERCC-6 isoform 1; DNA excision repair protein ERCC-6; excision repair cross-complementation group 6; excision repair cross-complementing rodent repair deficiency, complementation group 6", "tax_id": 10116, "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861); UV-sensitive syndrome (Disease Ontology:DOID:0060240); colorectal carcinoma (Disease Ontology:DOID:0080199); primary ovarian insufficiency 11 (Disease Ontology:DOID:0080868); Cockayne syndrome B (Disease Ontology:DOID:0080908); cerebrooculofacioskeletal syndrome 1 (Disease Ontology:DOID:0080911); age related macular degeneration 5 (Disease Ontology:DOID:0110028); De Sanctis-Cacchione syndrome (Disease Ontology:DOID:0112158); stomach cancer (Disease Ontology:DOID:10534); lung cancer (Disease Ontology:DOID:1324); polyneuropathy due to drug (Disease Ontology:DOID:14184); transient cerebral ischemia (Disease Ontology:DOID:224); larynx cancer (Disease Ontology:DOID:2596); Cockayne syndrome (Disease Ontology:DOID:2962); middle cerebral artery infarction (Disease Ontology:DOID:3525); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); macular degeneration (Disease Ontology:DOID:4448); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (rno:306274); (R-RNO-5250924); (R-RNO-6781823); (R-RNO-6782135); (R-RNO-6782210); (R-RNO-73762)", "pathway_count": 6, "publication_count": 3, "publication_id_list": "22673903;29393594;31644904", "class_list": "", "function": "Rat Model of Cockayne Syndrome Neurological Disease., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 20, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0004386 helicase activity;GO:0003682 chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0008023 transcription elongation factor complex;GO:0016604 nuclear body", "go_biological_process": "GO:0006281 DNA repair;GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0097680 double-strand break repair via classical nonhomologous end joining;GO:0000303 response to superoxide;GO:0034243 regulation of transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2JTU1-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2K033-1", "uniprot_id": [ { "id": "A0A0G2K033_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2K033", "type": "external" } ], "mass": 120264.0, "length": 1098, "protein_name": "ubiquitinyl hydrolase 1", "gene_name": "Usp36", "organism": "Rat", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 36", "refseq_ac": [ { "id": "NP_001100539", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100539", "type": "external" } ], "gene_names_uniprotkb": "Usp36", "gene_names_refseq": "Usp36", "protein_names_uniprotkb": "ubiquitinyl hydrolase 1; 3.4.19.12", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 36; ubiquitin specific protease 36", "tax_id": 10116, "disease": "congenital heart disease (Disease Ontology:DOID:1682); primary ovarian insufficiency (Disease Ontology:DOID:5426)", "pathway": " (rno:303700)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "27445338", "class_list": "", "function": "USP36 actions extend beyond TrkA because the presence of USP36 interferes with Nedd4-2-dependent Kv7.2/3 channel regulation., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, 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Interacts with the TP53 protein to control genes that are important in proliferation and in the DNA-damage response. Mechanistically, the interaction inhibits the DNA binding and transcriptional activity of TP53/p53. 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RGD1305845; Styxl1", "protein_names_uniprotkb": "Serine/threonine/tyrosine interacting-like 1", "protein_names_refseq": "map kinase phosphatase-like protein MK-STYX; serine/threonine/tyrosine-interacting-like protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:360792)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "25479605", "class_list": "", "function": "Data suggest that MK-STYX may be a regulator of RhoA signaling, and implicate this pseudophosphatase as a regulator of neuronal differentiation Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019212 phosphatase inhibitor activity;GO:0019903 protein phosphatase binding;GO:0001691 pseudophosphatase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0010976 positive regulation of neuron projection development;GO:2001244 positive regulation of intrinsic apoptotic signaling pathway;GO:2001242 regulation of intrinsic apoptotic signaling pathway;GO:0062030 negative regulation of stress granule assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "G3V9J5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "G3V9T7-1", "uniprot_id": [ { "id": "GET3_RAT", "url": "https://www.uniprot.org/uniprot/G3V9T7", "type": "external" } ], "mass": 38823.0, "length": 348, "protein_name": "ATPase Get3", "gene_name": "Get3", "organism": "Rat", "refseq_name": "ATPase GET3", "refseq_ac": [ { "id": "NP_001093975", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093975", "type": "external" } ], "gene_names_uniprotkb": "Get3; Asna1; Trc40", "gene_names_refseq": "Asna1; Get3", "protein_names_uniprotkb": "ATPase Get3; 3.6.4.-; Arsenical pump-driving ATPase; Arsenite-stimulated ATPase; Guided entry of tail-anchored proteins factor 3, ATPase", "protein_names_refseq": "ATPase ASNA1; ATPase GET3; arsA arsenite transporter, ATP-binding, homolog 1; arsenical pump-driving ATPase; arsenite-stimulated ATPase", "tax_id": 10116, "disease": "dilated cardiomyopathy (Disease Ontology:DOID:12930); cancer (Disease Ontology:DOID:162)", "pathway": " (rno:288919)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23041287;27226539", "class_list": "", "function": "ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1/WRB and CAMLG/GET2, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the GET1-CAMLG receptor, and returning it to the cytosol to initiate a new round of targeting., [UniProtKB, PubMed, PubMed, HAMAP]; Investigated the role of endogenous WRB and CAML in Asna1 tail-anchored protein insertion as well as their association, concentration, and stoichiometry in liver microsomes Erratum:[J Biol Chem. 2016 Sep 2;291(36):18855. doi: 10.1074/jbc.A115.707752. 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Parkinson's disease (Disease Ontology:DOID:14330); osteoarthritis (Disease Ontology:DOID:8398)", "pathway": " (rno:252835); (R-RNO-2129379)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "26010756;37310547", "class_list": "", "function": "Gdf-5 induced the expression of the alpha5 sub-unit, while Bmp-7 induced the expression of the alphaV sub-unit. Publication Status: Online-Only, [RefSeq, PubMed]; Growth differentiation factor 5 inhibits lipopolysaccharide-mediated pyroptosis of nucleus pulposus mesenchymal stem cells via RhoA signaling pathway., [RefSeq, PubMed]; Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstly, positively regulates differentiation of chondrogenic tissue through its binding of high affinity with BMPR1B and of less affinity with BMPR1A, leading to induction of SMAD1-SMAD5-SMAD8 complex phosphorylation and then SMAD protein signaling transduction. Secondly, negatively regulates chondrogenic differentiation through its interaction with NOG. Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8. Binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion by monocytes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 14, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0042802 identical protein binding;GO:0005125 cytokine activity;GO:0008083 growth factor activity;GO:0036122 BMP binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:2001054 negative regulation of mesenchymal cell apoptotic process;GO:0040014 regulation of multicellular organism growth;GO:0045666 positive regulation of neuron differentiation;GO:0050680 negative regulation of epithelial cell proliferation;GO:0043524 negative regulation of neuron apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "M0RAY4-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0RC77-1", "uniprot_id": [ { "id": "M0RC77_RAT", "url": "https://www.uniprot.org/uniprot/M0RC77", "type": "external" } ], "mass": 34369.0, "length": 306, "protein_name": "Kynurenine formamidase", "gene_name": "Afmid", "organism": "Rat", "refseq_name": "kynurenine formamidase", "refseq_ac": [ { "id": "NP_001104836", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104836", "type": "external" } ], "gene_names_uniprotkb": "Afmid; AFMID", "gene_names_refseq": "Afmid", "protein_names_uniprotkb": "Kynurenine formamidase; 3.5.1.9; Arylformamidase; FKF; KFA; KFase; N-formylkynurenine formamidase", "protein_names_refseq": "kynurenine formamidase", "tax_id": 10116, "disease": "", "pathway": " (rno:688283)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;29393594", "class_list": "", "function": "Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.5.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.9", "type": "external" } ], "go_molecular_function": "GO:0004061 arylformamidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0019441 L-tryptophan catabolic process to kynurenine;GO:0034354 'de novo' NAD+ biosynthetic process from L-tryptophan", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "M0RC77-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "M0RDK4-1", "uniprot_id": [ { "id": "M0RDK4_RAT", "url": "https://www.uniprot.org/uniprot/M0RDK4", "type": "external" } ], "mass": 106485.0, "length": 974, "protein_name": "Membrane-associated phosphatidylinositol transfer protein 3", "gene_name": "Pitpnm3", "organism": "Rat", "refseq_name": "membrane-associated phosphatidylinositol transfer protein 3", "refseq_ac": [ { "id": "NP_001417042", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417042", "type": "external" } ], "gene_names_uniprotkb": "Pitpnm3", "gene_names_refseq": "Pitpnm3", "protein_names_uniprotkb": "Membrane-associated phosphatidylinositol transfer protein 3; Phosphatidylinositol transfer protein, membrane-associated 3; Pyk2 N-terminal domain-interacting receptor 1", "protein_names_refseq": "membrane-associated phosphatidylinositol transfer protein 3", "tax_id": 10116, "disease": "cone-rod dystrophy 5 (Disease Ontology:DOID:0111010)", "pathway": " (R-RNO-1483226)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro). Binds calcium ions., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004620 phospholipase activity;GO:0005509 calcium ion binding;GO:0005548 phospholipid transporter activity;GO:0008289 lipid binding;GO:0030971 receptor tyrosine kinase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0012505 endomembrane system;GO:0044297 cell body;GO:0042995 cell projection", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "M0RDK4-1", "record_type": "protein", "filter_code": "0000000.0000111.010000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q3MIE7-1", "uniprot_id": [ { "id": "Q3MIE7_RAT", "url": "https://www.uniprot.org/uniprot/Q3MIE7", "type": "external" } ], "mass": 23187.0, "length": 211, "protein_name": "COMM domain containing 9", "gene_name": "Commd9", "organism": "Rat", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "Commd9", "gene_names_refseq": "", "protein_names_uniprotkb": "COMM domain containing 9", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:295956); (R-RNO-6798695); (R-RNO-8951664)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0032991 protein-containing complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0042632 cholesterol homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3MIE7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q4KLJ4-1", "uniprot_id": [ { "id": "Q4KLJ4_RAT", "url": "https://www.uniprot.org/uniprot/Q4KLJ4", "type": "external" } ], "mass": 54846.0, "length": 494, "protein_name": "Ribitol-5-phosphate transferase", "gene_name": "Fkrp", "organism": "Rat", "refseq_name": "ribitol 5-phosphate transferase FKRP", "refseq_ac": [ { "id": "NP_001020849", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020849", "type": "external" } ], "gene_names_uniprotkb": "Fkrp", "gene_names_refseq": "Fkrp", "protein_names_uniprotkb": "Ribitol-5-phosphate transferase", "protein_names_refseq": "ribitol 5-phosphate transferase FKRP", "tax_id": 10116, "disease": "Walker-Warburg syndrome (Disease Ontology:DOID:0050560); muscular dystrophy-dystroglycanopathy type B1 (Disease Ontology:DOID:0050588); autosomal recessive limb-girdle muscular dystrophy type 2I (Disease Ontology:DOID:0110299); muscular dystrophy-dystroglycanopathy type B5 (Disease Ontology:DOID:0110635); congenital muscular dystrophy-dystroglycanopathy type A5 (Disease Ontology:DOID:0111241); limb-girdle muscular dystrophy (Disease Ontology:DOID:11724); dilated cardiomyopathy (Disease Ontology:DOID:12930); muscular dystrophy (Disease Ontology:DOID:9884)", "pathway": " (rno:308390); (R-RNO-9939291)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A6J8C8", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0043236 laminin binding;GO:0002162 dystroglycan binding;GO:0016780 phosphotransferase activity, for other substituted phosphate groups", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005615 extracellular space;GO:0005791 rough endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0042383 sarcolemma", "go_biological_process": "GO:0043403 skeletal muscle tissue regeneration;GO:0060538 skeletal muscle organ development;GO:0097305 response to alcohol;GO:0001701 in utero embryonic development;GO:0003016 respiratory system process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q4KLJ4-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q4V894-1", "uniprot_id": [ { "id": "Q4V894_RAT", "url": "https://www.uniprot.org/uniprot/Q4V894", "type": "external" } ], "mass": 37783.0, "length": 334, "protein_name": "Cathepsin R", "gene_name": "Ctsr", "organism": "Rat", "refseq_name": "cathepsin R precursor", "refseq_ac": [ { "id": "NP_783171", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_783171", "type": "external" } ], "gene_names_uniprotkb": "Ctsr", "gene_names_refseq": "Cts6; Ctsr", "protein_names_uniprotkb": "Cathepsin R", "protein_names_refseq": "cathepsin 6; cathepsin R precursor", "tax_id": 10116, "disease": "COVID-19 (Disease Ontology:DOID:0080600); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); alcohol use disorder (Disease Ontology:DOID:1574); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (rno:290975)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "E9PTT3", "ec_number_list": [], "go_molecular_function": "GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005764 lysosome", "go_biological_process": "GO:0051603 proteolysis involved in protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q4V894-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q568Y6-1", "uniprot_id": [ { "id": "Q568Y6_RAT", "url": "https://www.uniprot.org/uniprot/Q568Y6", "type": "external" } ], "mass": 53174.0, "length": 468, "protein_name": "DNA methyltransferase 1-associated protein 1", "gene_name": "Dmap1", "organism": "Rat", "refseq_name": "DNA methyltransferase 1-associated protein 1", "refseq_ac": [ { "id": "NP_001015006", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001015006", "type": "external" } ], "gene_names_uniprotkb": "Dmap1", "gene_names_refseq": "Dmap1", "protein_names_uniprotkb": "DNA methyltransferase 1-associated protein 1", "protein_names_refseq": "DNA methyltransferase 1-associated protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:298447)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003714 transcription corepressor activity;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0035267 NuA4 histone acetyltransferase complex", "go_biological_process": "GO:0042307 positive regulation of protein import into nucleus;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006281 DNA repair;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q568Y6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q569A7-1", "uniprot_id": [ { "id": "Q569A7_RAT", "url": "https://www.uniprot.org/uniprot/Q569A7", "type": "external" } ], "mass": 31190.0, "length": 281, "protein_name": "diphthine methyl ester synthase", "gene_name": "Dph5", "organism": "Rat", "refseq_name": "diphthine methyl ester synthase", "refseq_ac": [ { "id": "NP_001017449", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017449", "type": "external" } ], "gene_names_uniprotkb": "Dph5", "gene_names_refseq": "CGI-30; Dph5; RGD1307867", "protein_names_uniprotkb": "diphthine methyl ester synthase; 2.1.1.314", "protein_names_refseq": "DPH5 homolog; diphthine methyl ester synthase; diphthine synthase", "tax_id": 10116, "disease": "neurodevelopmental disorder with short stature, prominent forehead, and feeding difficulties (Disease Ontology:DOID:0070479)", "pathway": " (rno:295394); (R-RNO-5358493)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "3.6.5.-", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.-", "type": "external" }, { "id": "2.1.1.314", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.314", "type": "external" } ], "go_molecular_function": "GO:0004164 diphthine synthase activity;GO:0141133 diphthine methyl ester synthase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0032259 methylation;GO:0017183 protein histidyl modification to diphthamide", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q569A7-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5BJQ1-1", "uniprot_id": [ { "id": "Q5BJQ1_RAT", "url": "https://www.uniprot.org/uniprot/Q5BJQ1", "type": "external" } ], "mass": 25631.0, "length": 239, "protein_name": "Claudin", "gene_name": "Cldn14", "organism": "Rat", "refseq_name": "claudin-14", "refseq_ac": [ { "id": "NP_001013447", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013447", "type": "external" } ], "gene_names_uniprotkb": "Cldn14", "gene_names_refseq": "Cldn14", "protein_names_uniprotkb": "Claudin", "protein_names_refseq": "claudin-14", "tax_id": 10116, "disease": "autosomal recessive nonsyndromic deafness 29 (Disease Ontology:DOID:0110487)", "pathway": " (rno:304073)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "33283646;33903003", "class_list": "", "function": "Claudin 14/15 play important roles in early wallerian degeneration after rat sciatic nerve injury., [RefSeq, PubMed]; Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia., [UniProtKB, UniProtKB]; Localization and regulation of claudin-14 in experimental models of hypercalcemia., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A6KPY6", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005923 bicellular tight junction;GO:0016328 lateral plasma membrane", "go_biological_process": "GO:0045471 response to ethanol", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q5BJQ1-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5BJV3-1", "uniprot_id": [ { "id": "Q5BJV3_RAT", "url": "https://www.uniprot.org/uniprot/Q5BJV3", "type": "external" } ], "mass": 37786.0, "length": 362, "protein_name": "Talin rod domain-containing protein 1", "gene_name": "Tlnrd1", "organism": "Rat", "refseq_name": "talin rod domain-containing protein 1", "refseq_ac": [ { "id": "NP_001013167", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013167", "type": "external" } ], "gene_names_uniprotkb": "Tlnrd1; Mesdc1", "gene_names_refseq": "Mesdc1; Tlnrd1", "protein_names_uniprotkb": "Talin rod domain-containing protein 1; Mesoderm development candidate 1", "protein_names_refseq": "mesoderm development candidate 1; talin rod domain-containing protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:308795)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Actin-binding protein which may have an oncogenic function and regulates cell proliferation, migration and invasion in cancer cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0001725 stress fiber", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q5BJV3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5BK45-1", "uniprot_id": [ { "id": "Q5BK45_RAT", "url": "https://www.uniprot.org/uniprot/Q5BK45", "type": "external" } ], "mass": 33394.0, "length": 293, "protein_name": "GTPase, IMAP family member 7", "gene_name": "Gimap7", "organism": "Rat", "refseq_name": "GTPase, IMAP family member 7", "refseq_ac": [ { "id": "NP_001019499", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019499", "type": "external" } ], "gene_names_uniprotkb": "Gimap7", "gene_names_refseq": "Gimap7; Ian3", "protein_names_uniprotkb": "GTPase, IMAP family member 7", "protein_names_refseq": "GTPase, IMAP family member 7", "tax_id": 10116, "disease": "", "pathway": " (rno:500113)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005811 lipid droplet", "go_biological_process": "GO:0046039 GTP metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5BK45-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5FVG7-1", "uniprot_id": [ { "id": "Q5FVG7_RAT", "url": "https://www.uniprot.org/uniprot/Q5FVG7", "type": "external" } ], "mass": 56988.0, "length": 507, "protein_name": "Tyrosine-protein kinase", "gene_name": "Srms", "organism": "Rat", "refseq_name": "tyrosine-protein kinase Srms", "refseq_ac": [ { "id": "NP_001011961", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011961", "type": "external" } ], "gene_names_uniprotkb": "Srms", "gene_names_refseq": "Srms", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "tyrosine-protein kinase Srms", "tax_id": 10116, "disease": "", "pathway": " (rno:296472); (R-RNO-8849472)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues. Also phosphorylates KHDRBS1/SAM68 and VIM on tyrosine residues. Phosphorylation of KHDRBS1 is EGF-dependent. Phosphorylates OTUB1, promoting deubiquitination of RPTOR., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "2.7.12.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.1", "type": "external" }, { "id": "2.7.10.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.1", "type": "external" }, { "id": "2.7.10.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2", "type": "external" }, { "id": "2.7.12.2", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.12.2", "type": "external" }, { "id": "2.7.1.40", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.40", "type": "external" }, { "id": "2.7.11.1", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1", "type": "external" }, { "id": "2.7.11.13", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.13", "type": "external" }, { "id": "2.7.10.4", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.4", "type": "external" }, { "id": "2.7.1.32", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.32", "type": "external" }, { "id": "2.7.1.82", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.82", "type": "external" }, { "id": "2.7.11.23", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.23", "type": "external" } ], "go_molecular_function": "GO:0004713 protein tyrosine kinase activity;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005102 signaling receptor binding;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0018108 peptidyl-tyrosine phosphorylation;GO:0030154 cell differentiation;GO:0038083 peptidyl-tyrosine autophosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q5FVG7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5FVI5-1", "uniprot_id": [ { "id": "Q5FVI5_RAT", "url": "https://www.uniprot.org/uniprot/Q5FVI5", "type": "external" } ], "mass": 17055.0, "length": 149, "protein_name": "Thioredoxin-like protein", "gene_name": "Txnl4b", "organism": "Rat", "refseq_name": "thioredoxin-like protein 4B isoform 1", "refseq_ac": [ { "id": "NP_001013913", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013913", "type": "external" } ], "gene_names_uniprotkb": "Txnl4b", "gene_names_refseq": "RGD1305127; Txnl4b", "protein_names_uniprotkb": "Thioredoxin-like protein", "protein_names_refseq": "Dim1-like protein; thioredoxin-like protein 4B isoform 1; thioredoxin-like protein 4B", "tax_id": 10116, "disease": "Burn-McKeown syndrome (Disease Ontology:DOID:0080695); cancer (Disease Ontology:DOID:162)", "pathway": " (rno:292008)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition., [UniProtKB, UniProtKB, UniProtKB]; Plays role in pre-mRNA splicing., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005681 spliceosomal complex;GO:0005682 U5 snRNP;GO:0046540 U4/U6 x U5 tri-snRNP complex;GO:0005654 nucleoplasm;GO:0071016 U12-type precatalytic spliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q5FVI5-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5J3I6-1", "uniprot_id": [ { "id": "Q5J3I6_RAT", "url": "https://www.uniprot.org/uniprot/Q5J3I6", "type": "external" } ], "mass": 34197.0, "length": 297, "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r88", "organism": "Rat", "refseq_name": "vomeronasal 1 receptor 88", "refseq_ac": [ { "id": "NP_001009513", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009513", "type": "external" } ], "gene_names_uniprotkb": "Vom1r88", "gene_names_refseq": "V1rc28; Vom1r88", "protein_names_uniprotkb": "Vomeronasal type-1 receptor", "protein_names_refseq": "vomernasal 1 receptor Vom1r88; vomeronasal 1 receptor 88; vomeronasal 1 receptor, C28; vomeronasal V1r-type receptor V1rc28; vomeronasal type-1 receptor 90", "tax_id": 10116, "disease": "", "pathway": " (rno:494233)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Putative pheromone receptor implicated in the regulation of social as well as reproductive behavior., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005550 pheromone binding;GO:0016503 pheromone receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0019236 response to pheromone;GO:0007606 sensory perception of chemical stimulus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q5J3I6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5J3K8-1", "uniprot_id": [ { "id": "Q5J3K8_RAT", "url": "https://www.uniprot.org/uniprot/Q5J3K8", "type": "external" } ], "mass": 34475.0, "length": 306, "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r108", "organism": "Rat", "refseq_name": "vomeronasal 1 receptor 108", "refseq_ac": [ { "id": "NP_001395757", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001395757", "type": "external" } ], "gene_names_uniprotkb": "Vom1r108", "gene_names_refseq": "V1rg6; Vom1r108", "protein_names_uniprotkb": "Vomeronasal type-1 receptor", "protein_names_refseq": "vomernasal 1 receptor Vom1r108; vomeronasal 1 receptor 108; vomeronasal 1 receptor, G6; vomeronasal V1r-type receptor V1rg6; vomeronasal type-1 receptor 3", "tax_id": 10116, "disease": "", "pathway": " (rno:299649)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16641100", "class_list": "", "function": "Putative pheromone receptor implicated in the regulation of social as well as reproductive behavior., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F7EXF9", "ec_number_list": [], "go_molecular_function": "GO:0005550 pheromone binding;GO:0016503 pheromone receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0019236 response to pheromone;GO:0007606 sensory perception of chemical stimulus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5J3K8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5PQR1-1", "uniprot_id": [ { "id": "Q5PQR1_RAT", "url": "https://www.uniprot.org/uniprot/Q5PQR1", "type": "external" } ], "mass": 68304.0, "length": 614, "protein_name": "Zinc finger protein 819", "gene_name": "Ceacam18; Zfp819", "organism": "Rat", "refseq_name": "zinc finger protein 175", "refseq_ac": [ { "id": "NP_001014039", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014039", "type": "external" } ], "gene_names_uniprotkb": "Ceacam18; Zfp819; Zfp819", "gene_names_refseq": "RGD1309564; Zfp819", "protein_names_uniprotkb": "Zinc finger protein 819", "protein_names_refseq": "zinc finger protein 175", "tax_id": 10116, "disease": "", "pathway": " (rno:308561); (R-RNO-212436)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F7EPA9", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q5PQR1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5S3S9-1", "uniprot_id": [ { "id": "Q5S3S9_RAT", "url": "https://www.uniprot.org/uniprot/Q5S3S9", "type": "external" } ], "mass": 74169.0, "length": 673, "protein_name": "Zinc finger and BTB domain containing 16", "gene_name": "Zbtb16", "organism": "Rat", "refseq_name": "zinc finger and BTB domain-containing protein 16", "refseq_ac": [ { "id": "NP_001013199", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013199", "type": "external" } ], "gene_names_uniprotkb": "Zbtb16", "gene_names_refseq": "Lx; Plzf; Zbtb16; Zfp145; Znf145", "protein_names_uniprotkb": "Zinc finger and BTB domain containing 16", "protein_names_refseq": "Polydactyly-luxate syndrome; promyelocytic leukemia zinc finger; zinc finger and BTB domain containing 16 protein; zinc finger and BTB domain-containing protein 16; zinc finger protein 145", "tax_id": 10116, "disease": "acute promyelocytic leukemia (Disease Ontology:DOID:0060318); caudal regression syndrome (Disease Ontology:DOID:0080700); polydactyly (Disease Ontology:DOID:1148)", "pathway": " (rno:353227); (R-RNO-8951664); (R-RNO-983168)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "26306672;27727328;36786377", "class_list": "", "function": "All homozygous PLZF gene mutated animals exhibited manifestations of a caudal regression syndrome including tail anomalies and serious size reduction and deformities of long bones, and oligo- or polydactyly on the hindlimbs. Erratum:[PLoS One. 2020 Jan 16;15(1):e0228139. PMID: 31945126] Publication Status: Online-Only, [RefSeq, PubMed]; GCN5 regulates ZBTB16 through acetylation, mediates osteogenic differentiation, and affects orthodontic tooth movement., [RefSeq, PubMed]; This study idnetifed that the ZBTB16 as inhibitors of neurite outgrowth., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0019904 protein domain specific binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0017053 transcription repressor complex;GO:0016604 nuclear body;GO:0016605 PML body", "go_biological_process": "GO:0043931 ossification involved in bone maturation;GO:0048133 male germ-line stem cell asymmetric division;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q5S3S9-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5XIH3-1", "uniprot_id": [ { "id": "Q5XIH3_RAT", "url": "https://www.uniprot.org/uniprot/Q5XIH3", "type": "external" } ], "mass": 50731.0, "length": 464, "protein_name": "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial", "gene_name": "Ndufv1", "organism": "Rat", "refseq_name": "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial", "refseq_ac": [ { "id": "NP_001006973", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006973", "type": "external" } ], "gene_names_uniprotkb": "Ndufv1", "gene_names_refseq": "Ndufv1", "protein_names_uniprotkb": "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; 7.1.1.2", "protein_names_refseq": "NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa; NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial", "tax_id": 10116, "disease": "mitochondrial complex I deficiency (Disease Ontology:DOID:0060536); nuclear type mitochondrial complex I deficiency 4 (Disease Ontology:DOID:0112082); mitochondrial metabolism disease (Disease Ontology:DOID:700)", "pathway": " (rno:293655); (R-RNO-611105); (R-RNO-6799198); (R-RNO-9837999)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "34502162;38843836", "class_list": "", "function": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [ { "id": "1.3.8.7", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.7", "type": "external" }, { "id": "1.3.8.8", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.8", "type": "external" }, { "id": "2.1.1.-", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.-", "type": "external" }, { "id": "1.-.-.-", "url": "https://www.rhea-db.org/rhea/?query=ec:1.-.-.-", "type": "external" }, { "id": "7.1.1.2", "url": "https://www.rhea-db.org/rhea/?query=ec:7.1.1.2", "type": "external" }, { "id": "3.6.4.10", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10", "type": "external" }, { "id": "2.1.1.320", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.320", "type": "external" }, { "id": "3.4.21.53", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.21.53", "type": "external" } ], "go_molecular_function": "GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0051287 NAD binding;GO:0008137 NADH dehydrogenase (ubiquinone) activity;GO:0010181 FMN binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045271 respiratory chain complex I", "go_biological_process": "GO:0006120 mitochondrial electron transport, NADH to ubiquinone;GO:0042775 mitochondrial ATP synthesis coupled electron transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q5XIH3-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0100000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q63550-1", "uniprot_id": [ { "id": "Q63550_RAT", "url": "https://www.uniprot.org/uniprot/Q63550", "type": "external" } ], "mass": 23028.0, "length": 206, "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "organism": "Rat", "refseq_name": "BPI fold containing family A, member 2F precursor", "refseq_ac": [ { "id": "NP_542953", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_542953", "type": "external" } ], "gene_names_uniprotkb": "Bpifa2f", "gene_names_refseq": "Bpifa2f; Smgb", "protein_names_uniprotkb": "BPI fold containing family A, member 2F", "protein_names_refseq": "BPI fold containing family A, member 2F precursor; neonatal submandibular gland protein B", "tax_id": 10116, "disease": "", "pathway": " (rno:54303)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "17984628", "class_list": "", "function": "These findings suggest that CORT promote the differentiation of type III cells, and moreover stimulate the production of secretory granules reactive for SMGB and WGA by acting on the terminal tubules of the developing rat submandibular gland., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001530 lipopolysaccharide binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0030141 secretory granule", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q63550-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q642B8-1", "uniprot_id": [ { "id": "Q642B8_RAT", "url": "https://www.uniprot.org/uniprot/Q642B8", "type": "external" } ], "mass": 65901.0, "length": 581, "protein_name": "Phosphatidylinositol glycan anchor biosynthesis, class Q", "gene_name": "Pigq", "organism": "Rat", "refseq_name": "phosphatidylinositol N-acetylglucosaminyltransferase subunit Q isoform 1", "refseq_ac": [ { "id": "NP_001007608", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007608", "type": "external" } ], "gene_names_uniprotkb": "Pigq", "gene_names_refseq": "Pigq", "protein_names_uniprotkb": "Phosphatidylinositol glycan anchor biosynthesis, class Q", "protein_names_refseq": "phosphatidylinositol N-acetylglucosaminyltransferase subunit Q isoform 1; phosphatidylinositol N-acetylglucosaminyltransferase subunit Q; phosphatidylinositol glycan, class Q", "tax_id": 10116, "disease": "multiple congenital anomalies-hypotonia-seizures syndrome 4 (Disease Ontology:DOID:0112213)", "pathway": " (rno:287159); (R-RNO-162710)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0016020 membrane", "go_biological_process": "GO:0006506 GPI anchor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q642B8-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6AXM6-1", "uniprot_id": [ { "id": "Q6AXM6_RAT", "url": "https://www.uniprot.org/uniprot/Q6AXM6", "type": "external" } ], "mass": 31091.0, "length": 277, "protein_name": "Intercellular adhesion molecule 2", "gene_name": "Icam2", "organism": "Rat", "refseq_name": "intercellular adhesion molecule 2 isoform 1 precursor", "refseq_ac": [ { "id": "NP_001007726", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007726", "type": "external" } ], "gene_names_uniprotkb": "Icam2", "gene_names_refseq": "Icam2", "protein_names_uniprotkb": "Intercellular adhesion molecule 2", "protein_names_refseq": "intercellular adhesion molecule 2 isoform 1 precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:360647); (R-RNO-198933); (R-RNO-216083); (R-RNO-5621575)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "23097088;23736379", "class_list": "", "function": "Data suggest that ICAM2 plays important role in apical dynamics/sperm head during spermatogenesis; ICAM2 surrounds heads of elongating/elongated spermatids in all stages of seminiferous epithelial cycle. Publication Status: Online-Only, [RefSeq, PubMed]; Flotillin-2 is involved with adhesion between UECs and the implanting blastocyst, whereas ICAM-2 is associated with the ability for UECs to be removed at the time of implantation., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0032154 cleavage furrow;GO:0071944 cell periphery;GO:0005902 microvillus;GO:0001931 uropod", "go_biological_process": "GO:0007155 cell adhesion;GO:0033627 cell adhesion mediated by integrin;GO:0007159 leukocyte cell-cell adhesion;GO:0036336 dendritic cell migration;GO:0098609 cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q6AXM6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6AY03-1", "uniprot_id": [ { "id": "Q6AY03_RAT", "url": "https://www.uniprot.org/uniprot/Q6AY03", "type": "external" } ], "mass": 40551.0, "length": 354, "protein_name": "Progestin and adipoQ receptor family member 8", "gene_name": "Paqr8", "organism": "Rat", "refseq_name": "membrane progestin receptor beta", "refseq_ac": [ { "id": "NP_001014121", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014121", "type": "external" } ], "gene_names_uniprotkb": "Paqr8", "gene_names_refseq": "Paqr8; Pmrbeta; RGD1311710", "protein_names_uniprotkb": "Progestin and adipoQ receptor family member 8", "protein_names_refseq": "membrane progestin receptor beta; progestin and adipoQ receptor family member VIII; progestin membrane receptor beta", "tax_id": 10116, "disease": "", "pathway": " (rno:316275)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "20977928;29393594;37699860", "class_list": "", "function": "Expression patterns of Paqr8 is low and homogeneous in the hypothalamus and more abundant in thalamic nuclei, and is likely to regulate sensory and cognitive functions in forebrain tissues of female rats., [RefSeq, PubMed]; PAQR8 and PAQR9 expression is altered in the ventral tegmental area of aged rats infected with varicella zoster virus., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003707 nuclear steroid receptor activity;GO:0005496 steroid binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0048545 response to steroid hormone", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q6AY03-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6DKY8-1", "uniprot_id": [ { "id": "Q6DKY8_RAT", "url": "https://www.uniprot.org/uniprot/Q6DKY8", "type": "external" } ], "mass": 66127.0, "length": 589, "protein_name": "Ectodermal-neural cortex 1", "gene_name": "Enc1", "organism": "Rat", "refseq_name": "ectoderm-neural cortex protein 1", "refseq_ac": [ { "id": "NP_001003401", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003401", "type": "external" } ], "gene_names_uniprotkb": "Enc1", "gene_names_refseq": "Enc1; Nrpb", "protein_names_uniprotkb": "Ectodermal-neural cortex 1", "protein_names_refseq": "ectoderm-neural cortex protein 1; nuclear restrict protein in brain", "tax_id": 10116, "disease": "", "pathway": " (rno:294674)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "19372205;19682578;27039095", "class_list": "", "function": "Knockdown of Enc1 protects neurons from apoptosis induced by oxygen-glucose deprivation associated with Nrf2 and HO-1., [RefSeq, PubMed]; Show that overexpression of the Nrp/b cDNA in C6/ST1 cells suppresses anchorage independence in vitro and tumorigenicity in vivo, altering their malignant nature towards a more benign phenotype., [RefSeq, PubMed]; The study further shows the physical association of ENC1 and F-actin, implicating the role of ENC1 in cytoskeletal reorganization during the differentiation of granulosa cells., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0043025 neuronal cell body;GO:0016363 nuclear matrix;GO:0000785 chromatin", "go_biological_process": "GO:0010976 positive regulation of neuron projection development;GO:0016567 protein ubiquitination;GO:0017148 negative regulation of translation;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0010499 proteasomal ubiquitin-independent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q6DKY8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6MG13-1", "uniprot_id": [ { "id": "Q6MG13_RAT", "url": "https://www.uniprot.org/uniprot/Q6MG13", "type": "external" } ], "mass": 119264.0, "length": 1044, "protein_name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16", "gene_name": "Dhx16", "organism": "Rat", "refseq_name": "pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16", "refseq_ac": [ { "id": "NP_997661", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997661", "type": "external" } ], "gene_names_uniprotkb": "Dhx16", "gene_names_refseq": "Dbp2; Ddx16; Dhx16", "protein_names_uniprotkb": "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; 3.6.4.13; DEAH-box protein 16", "protein_names_refseq": "DEAH (Asp-Glu-Ala-His) box polypeptide 16; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16", "tax_id": 10116, "disease": "", "pathway": " (rno:294232); (R-RNO-72163)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Required for pre-mRNA splicing as a component of the spliceosome. Contributes to pre-mRNA splicing after spliceosome formation and prior to the first transesterification reaction. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. Also plays a role in innate antiviral response by acting as a pattern recognition receptor sensing splicing signals in viral RNA. Mechanistically, TRIM6 promotes the interaction between unanchored 'Lys-48'-polyubiquitin chains and DHX16, leading to DHX16 interaction with RIGI and ssRNA to amplify RIGI-dependent innate antiviral immune responses., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 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"secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q6TXE4-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7TMZ5-1", "uniprot_id": [ { "id": "Q7TMZ5_RAT", "url": "https://www.uniprot.org/uniprot/Q7TMZ5", "type": "external" } ], "mass": 23451.0, "length": 203, "protein_name": "ADP-ribosylation factor like GTPase 6 interacting protein 1", "gene_name": "Arl6ip1", "organism": "Rat", "refseq_name": "ADP-ribosylation factor-like protein 6-interacting protein 1", "refseq_ac": [ { "id": "NP_942032", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_942032", "type": "external" } ], "gene_names_uniprotkb": "Arl6ip1", "gene_names_refseq": "Arl6ip1", "protein_names_uniprotkb": "ADP-ribosylation factor like GTPase 6 interacting protein 1", "protein_names_refseq": "ADP-ribosylation factor like GTPase 6 interacting protein 1; ADP-ribosylation factor-like 6 interacting protein 1; ADP-ribosylation factor-like protein 6-interacting protein 1; ADP-ribosylation-like factor 6-interacting protein", "tax_id": 10116, "disease": "hereditary spastic paraplegia 61 (Disease Ontology:DOID:0110812); hereditary spastic paraplegia (Disease Ontology:DOID:2476)", "pathway": " (rno:293551)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 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0.1, "record_id": "Q99PV2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9ESV7-1", "uniprot_id": [ { "id": "Q9ESV7_RAT", "url": "https://www.uniprot.org/uniprot/Q9ESV7", "type": "external" } ], "mass": 33128.0, "length": 310, "protein_name": "Caudal type homeo box 2", "gene_name": "Cdx2", "organism": "Rat", "refseq_name": "homeobox protein CDX-2", "refseq_ac": [ { "id": "NP_076453", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_076453", "type": "external" } ], "gene_names_uniprotkb": "Cdx2", "gene_names_refseq": "Cdx2", "protein_names_uniprotkb": "Caudal type homeo box 2", "protein_names_refseq": "homeobox protein CDX-2", "tax_id": 10116, "disease": "Barrett's esophagus (Disease Ontology:DOID:9206)", "pathway": " (rno:66019)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12223343;15019784;26268420", "class_list": "", "function": "Cdx2 expression levels, elevated by IPTG treatment, are not affected by Slfn3-specific siRNA, suggesting that Cdx2 lies upstream of Slfn3 in IEC-Cdx1-L1 enterocytes., [RefSeq, PubMed]; Cdx2-regulated genes were elucidated,which suggested the functions of Cdx2 in cell fate decision and maintenance of intestinal epithelium, [RefSeq, PubMed]; Data indicate HB-EGF gene expression can be regulated by Cdx2 in intestinal epithelial (IEC-6) cells, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, 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condensed nuclear chromosome;GO:0005634 nucleus;GO:0017053 transcription repressor complex;GO:0032991 protein-containing complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0008284 positive regulation of cell population proliferation;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9ESV7-1", "record_type": "protein", "filter_code": "0000000.0000111.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9JHF3-1", "uniprot_id": [ { "id": "PTGES_RAT", "url": "https://www.uniprot.org/uniprot/Q9JHF3", "type": "external" } ], "mass": 17273.0, "length": 153, "protein_name": "Prostaglandin E synthase", "gene_name": "Ptges", "organism": "Rat", "refseq_name": "prostaglandin E synthase", "refseq_ac": [ { "id": "NP_067594", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_067594", "type": "external" } ], "gene_names_uniprotkb": "Ptges; Pges; Pig12", "gene_names_refseq": "Pges; Ptges; mPGES-1", "protein_names_uniprotkb": "Prostaglandin E synthase; 1.11.1.-; 2.5.1.18; 5.3.99.3; Glutathione peroxidase PTGES; Glutathione transferase PTGES; Inducible prostaglandin E synthase; Microsomal prostaglandin E synthase 1; mPGES-1", "protein_names_refseq": "glutathione peroxidase PTGES; glutathione transferase PTGES; inducible prostaglandin E synthase; microsomal prostaglandin E synthase 1; prostaglandin E synthase", "tax_id": 10116, "disease": "", "pathway": " (rno:59103); (R-RNO-2162123)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "10754227;10869354;11067848;23284082;26543101;29891860;39417702", "class_list": "", "function": "In conclusion, microsomal PGES-1 plays a critical role in the continuous suppression of motor function in the post-bowel obstruction state. Publication Status: Online-Only, [RefSeq, PubMed]; PTGES is involved in myofibroblast differentiation via HIF-1alpha-dependent glycolysis pathway., [RefSeq, PubMed]; Suggest pivotal role of COX-2-mPGES-1-PGE2 axis in vascular calcification. Inhibition of COX-2 or mPGES-1 may increase the risk of calcification and subsequent adverse cardiovascular events during chronic renal failure., [RefSeq, PubMed]; Terminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway. Catalyzes the glutathione-dependent oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) in response to inflammatory stimuli (PubMed:10869354, PubMed:11067848). Plays a key role in inflammation response, fever and pain (By similarity). Also catalyzes the oxidoreduction of endocannabinoids into prostaglandin glycerol esters and PGG2 into 15-hydroperoxy-PGE2. In addition, displays low glutathione transferase and glutathione-dependent peroxidase activities, toward 1-chloro-2,4-dinitrobenzene and 5-hydroperoxyicosatetraenoic acid (5-HPETE), respectively (By similarity)., [UniProtKB, UniProtKB, PubMed, PubMed, UniProtKB]; Using metabolic profiling and exploratory rat toxicity studies, a new and active mPGES-1 inhibitor with improved margins to chemically induced kidney toxicity in rats has been identified., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, 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"type": "external" }, { "id": "1.11.1.12", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.12", "type": "external" }, { "id": "1.11.1.9", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.9", "type": "external" } ], "go_molecular_function": "GO:0004667 prostaglandin-D synthase activity;GO:0004364 glutathione transferase activity;GO:0043295 glutathione binding;GO:0050220 prostaglandin-E synthase activity;GO:0004602 glutathione peroxidase activity", "go_cellular_component": "GO:0005641 nuclear envelope lumen;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0031620 regulation of fever generation;GO:0008285 negative regulation of cell population proliferation;GO:0032496 response to lipopolysaccharide;GO:0051592 response to calcium ion;GO:0019233 sensory perception of pain", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9JHF3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JT23-1", "uniprot_id": [ { "id": "A0A0G2JT23_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JT23", "type": "external" } ], "mass": 57378.0, "length": 499, "protein_name": "Nuclear receptor-binding protein 2", "gene_name": "Nrbp2", "organism": "Rat", "refseq_name": "nuclear receptor-binding protein 2", "refseq_ac": [ { "id": "NP_001402033", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001402033", "type": "external" } ], "gene_names_uniprotkb": "Nrbp2", "gene_names_refseq": "Nrbp2", "protein_names_uniprotkb": "Nuclear receptor-binding protein 2", "protein_names_refseq": "nuclear receptor-binding protein 2", "tax_id": 10116, "disease": "", "pathway": " (rno:680451)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "May regulate apoptosis of neural progenitor cells during their differentiation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004672 protein kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0012505 endomembrane system", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0043524 negative regulation of neuron apoptotic process;GO:0030182 neuron differentiation;GO:0016242 negative regulation of macroautophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JT23-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A0G2JVA8-1", "uniprot_id": [ { "id": "A0A0G2JVA8_RAT", "url": "https://www.uniprot.org/uniprot/A0A0G2JVA8", "type": "external" } ], "mass": 58096.0, "length": 537, "protein_name": "Keratin 90", "gene_name": "Krt90", "organism": "Rat", "refseq_name": "keratin, type II cytoskeletal cochleal isoform 1", "refseq_ac": [ { "id": "NP_001426766", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001426766", "type": "external" } ], "gene_names_uniprotkb": "Krt90; Kb15", "gene_names_refseq": "Kb15; Krt90", "protein_names_uniprotkb": "Keratin 90", "protein_names_refseq": "keratin, type II cytoskeletal cochleal isoform 1; keratin, type II cytoskeletal cochleal; type II keratin Kb15", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, 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coiled-coil-helix-coiled-coil-helix domain-containing protein 5", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F7FF20", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0045333 cellular respiration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B0BMY5-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000001000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B1H215-1", "uniprot_id": [ { "id": "B1H215_RAT", "url": "https://www.uniprot.org/uniprot/B1H215", "type": "external" } ], "mass": 71115.0, "length": 630, "protein_name": "Nuclear receptor coactivator 4", "gene_name": "Ncoa4", "organism": "Rat", "refseq_name": "nuclear receptor coactivator 4 isoform X1", "refseq_ac": [ { "id": "XP_006252722", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006252722", "type": "external" } ], "gene_names_uniprotkb": "Ncoa4", "gene_names_refseq": "Ncoa4", "protein_names_uniprotkb": "Nuclear receptor coactivator 4", "protein_names_refseq": "nuclear receptor coactivator 4 isoform X1", "tax_id": 10116, "disease": "prostate cancer (Disease Ontology:DOID:10283); polycystic ovary syndrome (Disease Ontology:DOID:11612); invasive ductal carcinoma (Disease Ontology:DOID:3008); ovarian carcinoma (Disease Ontology:DOID:4001)", "pathway": " (rno:619385)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A6KFW8", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity", "go_cellular_component": "GO:0044754 autolysosome", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis;GO:0009725 response to hormone;GO:0006622 protein targeting to lysosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B1H215-1", "record_type": "protein", "filter_code": "0000000.0000011.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B1H219-1", "uniprot_id": [ { "id": "B1H219_RAT", "url": "https://www.uniprot.org/uniprot/B1H219", "type": "external" } ], "mass": 38738.0, "length": 348, "protein_name": "Dickkopf-related protein 3", "gene_name": "Dkk3", "organism": "Rat", "refseq_name": "dickkopf-related protein 3 precursor", "refseq_ac": [ { "id": "NP_612528", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_612528", "type": "external" } ], "gene_names_uniprotkb": "Dkk3", "gene_names_refseq": "Dkk3; Reic; p29", "protein_names_uniprotkb": "Dickkopf-related protein 3", "protein_names_refseq": "dickkopf 3 homolog; dickkopf homolog 3; dickkopf-related protein 3 precursor; dickkopf-related protein 3", "tax_id": 10116, "disease": "", "pathway": " (rno:171548)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12586781;12857724;28259940;35658977;37144413", "class_list": "", "function": "Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease., [UniProtKB, UniProtKB, UniProtKB]; DKK3 ameliorates neuropathic pain via inhibiting ASK-1/JNK/p-38-mediated microglia polarization and neuroinflammation. Publication Status: Online-Only, [RefSeq, PubMed]; DKK3 expression negatively regulates the osteogenic differentiation of dental follicle cells., [RefSeq, PubMed]; Data do not support that thyroxine-binding protein p29 has a functional relationship with D2, but expression of p29 in the blood-CSF barrier suggests that it might be involved in T(4) transport to and from the CSF, [RefSeq, PubMed]; Role of Dickkopf-3 in Blood Pressure Regulation in Mice and Hypertensive Rats., [RefSeq, PubMed]; WNT7A can specifically act via a Frizzled-5.LRP6 receptor complex in PC12 cells and that this activity can be antagonized by Dickkopf-1 and Dickkopf-3., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0048019 receptor antagonist activity;GO:0039706 co-receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005576 extracellular region", "go_biological_process": "GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0016055 Wnt signaling pathway;GO:0045892 negative regulation of DNA-templated transcription;GO:0030325 adrenal gland development;GO:0032348 negative regulation of aldosterone biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "B1H219-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000001000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "B1WC26-1", "uniprot_id": [ { "id": "B1WC26_RAT", "url": "https://www.uniprot.org/uniprot/B1WC26", "type": "external" } ], "mass": 40051.0, "length": 359, "protein_name": "N-acetylneuraminate-9-phosphate synthase", "gene_name": "Nans", "organism": "Rat", "refseq_name": "sialic acid synthase", "refseq_ac": [ { "id": "NP_001100125", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100125", "type": "external" } ], "gene_names_uniprotkb": "Nans", "gene_names_refseq": "Nans", "protein_names_uniprotkb": "N-acetylneuraminate-9-phosphate synthase; 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