[ { "uniprot_canonical_ac": "A0A286ZSM8-1", "uniprot_id": [ { "id": "A0A286ZSM8_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZSM8", "type": "external" } ], "mass": 91463.0, "length": 814, "protein_name": "Phosphoinositide 3-kinase adapter protein 1", "gene_name": "PIK3AP1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PIK3AP1", "gene_names_refseq": "", "protein_names_uniprotkb": "Phosphoinositide 3-kinase adapter protein 1; B-cell adapter for phosphoinositide 3-kinase; B-cell phosphoinositide 3-kinase adapter protein 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1257604); (R-SSC-6811558); (R-SSC-983695)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0042802 identical protein binding;GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005737 cytoplasm", "go_biological_process": "GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0050727 regulation of inflammatory response;GO:0034134 toll-like receptor 2 signaling pathway;GO:0034142 toll-like receptor 4 signaling pathway;GO:0034154 toll-like receptor 7 signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZSM8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZSP5-1", "uniprot_id": [ { "id": "A0A286ZSP5_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZSP5", "type": "external" } ], "mass": 34856.0, "length": 311, "protein_name": "Olfactory receptor", "gene_name": "LOC100155936", "organism": "Pig", "refseq_name": "olfactory receptor 4F15-like", "refseq_ac": [ { "id": "XP_001929446", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929446", "type": "external" } ], "gene_names_uniprotkb": "LOC100155936", "gene_names_refseq": "LOC100155936", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 4F15-like", "tax_id": 9823, "disease": "", "pathway": " (ssc:100155936)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZSP5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZSR2-1", "uniprot_id": [ { "id": "A0A286ZSR2_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZSR2", "type": "external" } ], "mass": 44354.0, "length": 394, "protein_name": "Phosphorylated adapter RNA export protein", "gene_name": "PHAX", "organism": "Pig", "refseq_name": "phosphorylated adapter RNA export protein", "refseq_ac": [ { "id": "XP_005661662", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005661662", "type": "external" } ], "gene_names_uniprotkb": "PHAX", "gene_names_refseq": "PHAX", "protein_names_uniprotkb": "Phosphorylated adapter RNA export protein; RNA U small nuclear RNA export adapter protein", "protein_names_refseq": "phosphorylated adapter RNA export protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:100515013); (R-SSC-6807505)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0140262 mRNA cap binding complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0015030 Cajal body;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0015031 protein transport;GO:0006408 snRNA export from nucleus;GO:0043489 RNA stabilization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZSR2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZSR7-1", "uniprot_id": [ { "id": "A0A286ZSR7_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZSR7", "type": "external" } ], "mass": 35493.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "LOC110258386", "organism": "Pig", "refseq_name": "olfactory receptor 6C3-like", "refseq_ac": [ { "id": "XP_020937332", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937332", "type": "external" } ], "gene_names_uniprotkb": "LOC110258386", "gene_names_refseq": "LOC110258386", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 6C3-like", "tax_id": 9823, "disease": "", "pathway": " (ssc:110258386)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZSR7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZSS0-1", "uniprot_id": [ { "id": "A0A286ZSS0_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZSS0", "type": "external" } ], "mass": 64481.0, "length": 591, "protein_name": "Transcription factor COE1", "gene_name": "EBF1", "organism": "Pig", "refseq_name": "transcription factor COE1 isoform X13", "refseq_ac": [ { "id": "XP_003359882", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003359882", "type": "external" } ], "gene_names_uniprotkb": "EBF1", "gene_names_refseq": "EBF1", "protein_names_uniprotkb": "Transcription factor COE1; Early B-cell factor", "protein_names_refseq": "transcription factor COE1 isoform X13", "tax_id": 9823, "disease": "", "pathway": " (ssc:100520467)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Key pioneer transcription factor of B-cell specification and commitment. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates. For instance, positively regulates many B-cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage. In addition to its role during lymphopoiesis, controls the thermogenic gene program in adipocytes during development and in response to environmental cold., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Transcriptional activator. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZSS0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZSS6-1", "uniprot_id": [ { "id": "A0A286ZSS6_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZSS6", "type": "external" } ], "mass": 36768.0, "length": 326, "protein_name": "Olfactory receptor", "gene_name": "LOC100154900", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC100154900", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZSS6-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZST1-1", "uniprot_id": [ { "id": "A0A286ZST1_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZST1", "type": "external" } ], "mass": 137258.0, "length": 1279, "protein_name": "Activating transcription factor 7 interacting protein", "gene_name": "ATF7IP", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ATF7IP", "gene_names_refseq": "", "protein_names_uniprotkb": "Activating transcription factor 7 interacting protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-3214841); (R-SSC-9843940); (R-SSC-9843970)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003714 transcription corepressor activity;GO:0016887 ATP hydrolysis activity;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016604 nuclear body;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0006346 DNA methylation-dependent constitutive heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZST1-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZST2-1", "uniprot_id": [ { "id": "A0A286ZST2_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZST2", "type": "external" } ], "mass": 209459.0, "length": 1875, "protein_name": "Protein RRP5 homolog", "gene_name": "PDCD11", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PDCD11", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein RRP5 homolog; Programmed cell death protein 11", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-6791226)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. 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Important in nervous system development., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030731 guanidinoacetate N-methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0032259 methylation;GO:0006601 creatine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZU36-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZVR5-1", "uniprot_id": [ { "id": "A0A286ZVR5_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZVR5", "type": "external" } ], "mass": 68736.0, "length": 632, "protein_name": "Phosphatidylinositol-binding clathrin assembly protein", "gene_name": "PICALM", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PICALM", "gene_names_refseq": "", "protein_names_uniprotkb": "Phosphatidylinositol-binding clathrin assembly protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-432722); (R-SSC-8856825); (R-SSC-8856828); (R-SSC-9696264)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Cytoplasmic adapter protein that plays a critical role in clathrin-mediated endocytosis which is important in processes such as internalization of cell receptors, synaptic transmission or removal of apoptotic cells. Recruits AP-2 and attaches clathrin triskelions to the cytoplasmic side of plasma membrane leading to clathrin-coated vesicles (CCVs) assembly. Furthermore, regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature. In addition to binding to clathrin, mediates the endocytosis of small R-SNARES (Soluble NSF Attachment Protein REceptors) between plasma membranes and endosomes including VAMP2, VAMP3, VAMP4, VAMP7 or VAMP8. In turn, PICALM-dependent SNARE endocytosis is required for the formation and maturation of autophagic precursors. Modulates thereby autophagy and the turnover of autophagy substrates such as MAPT/TAU or amyloid precursor protein cleaved C-terminal fragment (APP-CTF)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005545 1-phosphatidylinositol binding;GO:0030276 clathrin binding;GO:0050750 low-density lipoprotein particle receptor binding;GO:0048156 tau protein binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit;GO:0030136 clathrin-coated vesicle", "go_biological_process": "GO:0048268 clathrin coat assembly;GO:0072583 clathrin-dependent endocytosis;GO:0046579 positive regulation of Ras protein signal transduction;GO:0097753 membrane bending;GO:0007409 axonogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZVR5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZU43-1", "uniprot_id": [ { "id": "A0A286ZU43_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZU43", "type": "external" } ], "mass": 38844.0, "length": 344, "protein_name": "MAP3K12 binding inhibitory protein 1", "gene_name": "MBIP", "organism": "Pig", "refseq_name": "MAP3K12-binding inhibitory protein 1 isoform X1", "refseq_ac": [ { "id": "XP_003128562", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003128562", "type": "external" } ], "gene_names_uniprotkb": "MBIP", "gene_names_refseq": "MBIP", "protein_names_uniprotkb": "MAP3K12 binding inhibitory protein 1", "protein_names_refseq": "MAP3K12-binding inhibitory protein 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100516143)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A5G2R6M6", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0004860 protein kinase inhibitor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0140672 ATAC complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0010628 positive regulation of gene expression;GO:0046330 positive regulation of JNK cascade;GO:0051726 regulation of cell cycle;GO:0045995 regulation of embryonic development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZU43-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZU56-1", "uniprot_id": [ { "id": "A0A286ZU56_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZU56", "type": "external" } ], "mass": 17516.0, "length": 149, "protein_name": "Large ribosomal subunit protein bL20m", "gene_name": "MRPL20", "organism": "Pig", "refseq_name": "39S ribosomal protein L20, mitochondrial", "refseq_ac": [ { "id": "XP_003127555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003127555", "type": "external" } ], "gene_names_uniprotkb": "MRPL20", "gene_names_refseq": "MRPL20", "protein_names_uniprotkb": "Large ribosomal subunit protein bL20m; 39S ribosomal protein L20, mitochondrial", "protein_names_refseq": "39S ribosomal protein L20, mitochondrial", "tax_id": 9823, "disease": "", "pathway": " (ssc:100511022); (R-SSC-5389840); (R-SSC-5419276); (R-SSC-9937383)", "pathway_count": 4, "publication_count": 5, "publication_id_list": "30089917;32543654;32602580;33878294;37141370", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019843 rRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005761 mitochondrial ribosome", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A286ZU56-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZU57-1", "uniprot_id": [ { "id": "A0A286ZU57_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZU57", "type": "external" } ], "mass": 35171.0, "length": 311, "protein_name": "Olfactory receptor", "gene_name": "LOC110260847", "organism": "Pig", "refseq_name": "olfactory receptor 6C2-like", "refseq_ac": [ { "id": "XP_020948774", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020948774", "type": "external" } ], "gene_names_uniprotkb": "LOC110260847", "gene_names_refseq": "LOC110260847", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 6C2-like", "tax_id": 9823, "disease": "", "pathway": " (ssc:100524494); (ssc:110260847)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZU57-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZU72-1", "uniprot_id": [ { "id": "A0A286ZU72_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZU72", "type": "external" } ], "mass": 80252.0, "length": 721, "protein_name": "Mitochondrial disaggregase", "gene_name": "CLPB", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CLPB", "gene_names_refseq": "", "protein_names_uniprotkb": "Mitochondrial disaggregase; Suppressor of potassium transport defect 3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Functions as a regulatory ATPase and participates in secretion/protein trafficking process. Has ATP-dependent protein disaggregase activity and is required to maintain the solubility of key mitochondrial proteins. Involved in mitochondrial-mediated antiviral innate immunity, activates RIG-I-mediated signal transduction and production of IFNB1 and pro-inflammatory cytokine IL6. 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Recognizes type II iodothyronine deiodinase/DIO2. Confers constitutive instability to HIPK2 through proteasomal degradation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1TNE4", "ec_number_list": [], "go_molecular_function": "GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0097413 Lewy body", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0000209 protein polyubiquitination;GO:0044314 protein K27-linked ubiquitination;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZUC3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZUC6-1", "uniprot_id": [ { "id": "A0A286ZUC6_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZUC6", "type": "external" } ], "mass": 35643.0, "length": 317, "protein_name": "Olfactory receptor", "gene_name": "LOC100154323", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC100154323", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZUC6-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZUD3-1", "uniprot_id": [ { "id": "A0A286ZUD3_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZUD3", "type": "external" } ], "mass": 44996.0, "length": 398, "protein_name": "Probable splicing factor YJU2B", "gene_name": "YJU2B", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "YJU2B", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable splicing factor YJU2B; 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(R-SSC-416482); (R-SSC-8980692); (R-SSC-9013026); (R-SSC-9013106); (R-SSC-9013148); (R-SSC-9013149); (R-SSC-9013404); (R-SSC-9013406); (R-SSC-9013408); (R-SSC-9013409); (R-SSC-9013423)", "pathway_count": 12, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, 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"uniprot_canonical_ac": "A0A286ZUE1-1", "uniprot_id": [ { "id": "A0A286ZUE1_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZUE1", "type": "external" } ], "mass": 16115.0, "length": 146, "protein_name": "MORN repeat-containing protein 4", "gene_name": "MORN4", "organism": "Pig", "refseq_name": "MORN repeat-containing protein 4 isoform X2", "refseq_ac": [ { "id": "XP_001929049", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929049", "type": "external" } ], "gene_names_uniprotkb": "MORN4", "gene_names_refseq": "MORN4", "protein_names_uniprotkb": "MORN repeat-containing protein 4", "protein_names_refseq": "MORN repeat-containing protein 4 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100158004)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays a role in promoting axonal degeneration following neuronal injury by toxic insult or trauma., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, 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"external" } ], "gene_names_uniprotkb": "RGS6", "gene_names_refseq": "RGS6", "protein_names_uniprotkb": "Regulator of G protein signaling 6", "protein_names_refseq": "regulator of G-protein signaling 6 isoform X5", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-418594); (R-SSC-6814122)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, 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10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZUE4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZUF4-1", "uniprot_id": [ { "id": "A0A286ZUF4_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZUF4", "type": "external" } ], "mass": 110034.0, "length": 1043, "protein_name": "Cytoplasmic polyadenylation element binding protein 2", "gene_name": "CPEB2", "organism": "Pig", "refseq_name": "cytoplasmic polyadenylation element-binding protein 2 isoform X1", "refseq_ac": [ { "id": "XP_020955979", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955979", "type": "external" } ], "gene_names_uniprotkb": "CPEB2", "gene_names_refseq": "CPEB2", "protein_names_uniprotkb": "Cytoplasmic polyadenylation element binding protein 2", "protein_names_refseq": "cytoplasmic polyadenylation element-binding protein 2 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100462674)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, 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"A0A286ZUH7_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZUH7", "type": "external" } ], "mass": 88260.0, "length": 822, "protein_name": "ATM interactor", "gene_name": "ATMIN", "organism": "Pig", "refseq_name": "ATM interactor", "refseq_ac": [ { "id": "XP_020952704", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020952704", "type": "external" } ], "gene_names_uniprotkb": "ATMIN", "gene_names_refseq": "ATMIN", "protein_names_uniprotkb": "ATM interactor", "protein_names_refseq": "ATM interactor", "tax_id": 9823, "disease": "", "pathway": " (ssc:110255220)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, 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Participates in mitochondrial translation. Also plays a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIGI-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy., [UniProtKB, UniProtKB]; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287AJQ9", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005516 calmodulin binding;GO:0005525 GTP binding;GO:0003746 translation elongation factor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0006412 translation;GO:0006414 translational elongation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZUI3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZUN5-1", "uniprot_id": [ { "id": "A0A286ZUN5_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZUN5", "type": "external" } ], "mass": 162370.0, "length": 1437, "protein_name": "Probable ATP-dependent DNA helicase HFM1", "gene_name": "HFM1", "organism": "Pig", "refseq_name": "probable ATP-dependent DNA helicase HFM1 isoform X5", "refseq_ac": [ { "id": "XP_013852841", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013852841", "type": "external" } ], "gene_names_uniprotkb": "HFM1", "gene_names_refseq": "HFM1", "protein_names_uniprotkb": "Probable ATP-dependent DNA helicase HFM1; 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Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, 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"go_cellular_component": "GO:0005576 extracellular region;GO:0005654 nucleoplasm;GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0033093 Weibel-Palade body", "go_biological_process": "GO:0090559 regulation of membrane permeability;GO:0001525 angiogenesis;GO:0006869 lipid transport;GO:0042157 lipoprotein metabolic process;GO:0045601 regulation of endothelial cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZUT8-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZUT9-1", "uniprot_id": [ { "id": "A0A286ZUT9_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZUT9", "type": "external" } ], "mass": 51851.0, "length": 457, "protein_name": "ADAM like decysin 1", "gene_name": "ADAMDEC1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ADAMDEC1", "gene_names_refseq": "", 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"gene_name": "GATAD1", "organism": "Pig", "refseq_name": "GATA zinc finger domain-containing protein 1 isoform X1", "refseq_ac": [ { "id": "XP_013835141", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013835141", "type": "external" } ], "gene_names_uniprotkb": "GATAD1", "gene_names_refseq": "GATAD1", "protein_names_uniprotkb": "GATA zinc finger domain-containing protein 1", "protein_names_refseq": "GATA zinc finger domain-containing protein 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100627096)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006355 regulation of DNA-templated transcription;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZUW8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZUZ1-1", "uniprot_id": [ { "id": "A0A286ZUZ1_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZUZ1", "type": "external" } ], "mass": 58619.0, "length": 521, "protein_name": "Sorting nexin-2", "gene_name": "SNX2", "organism": "Pig", "refseq_name": "sorting nexin-2 isoform X2", "refseq_ac": [ { "id": "XP_013842153", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013842153", "type": "external" } ], "gene_names_uniprotkb": "SNX2", "gene_names_refseq": "SNX2", "protein_names_uniprotkb": "Sorting nexin-2", "protein_names_refseq": "sorting nexin-2 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100626970); (R-SSC-432722)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC). Can sense membrane curvature and has in vitro vesicle-to-membrane remodeling activity. Required for retrograde endosome-to-TGN transport of TGN38. Promotes KALRN- and RHOG-dependent but retromer-independent membrane remodeling such as lamellipodium formation; the function is dependent on GEF activity of KALRN., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8D1YH99", "ec_number_list": [], "go_molecular_function": "GO:0035091 phosphatidylinositol binding;GO:0005158 insulin receptor binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0005154 epidermal growth factor receptor binding", "go_cellular_component": "GO:0005768 endosome;GO:0005829 cytosol;GO:0030027 lamellipodium;GO:0031901 early endosome membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0034498 early endosome to Golgi transport;GO:0072673 lamellipodium morphogenesis;GO:0042147 retrograde transport, endosome to Golgi", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZUZ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZV40-1", "uniprot_id": [ { "id": "A0A286ZV40_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZV40", "type": "external" } ], "mass": 37045.0, "length": 331, "protein_name": "Testis-specific Y-encoded-like protein 3", "gene_name": "LOC106506652", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC106506652", "gene_names_refseq": "", "protein_names_uniprotkb": "Testis-specific Y-encoded-like protein 3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0006334 nucleosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZV40-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZV42-1", "uniprot_id": [ { "id": "A0A286ZV42_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZV42", "type": "external" } ], "mass": 74970.0, "length": 677, "protein_name": "Epithelial splicing regulatory protein 1", "gene_name": "ESRP1", "organism": "Pig", "refseq_name": "epithelial splicing regulatory protein 1 isoform X2", "refseq_ac": [ { "id": "XP_005663019", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005663019", "type": "external" } ], "gene_names_uniprotkb": "ESRP1", "gene_names_refseq": "ESRP1", "protein_names_uniprotkb": "Epithelial splicing regulatory protein 1; RNA-binding motif protein 35A; RNA-binding protein 35A", "protein_names_refseq": "epithelial splicing regulatory protein 1 isoform X2", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. Regulates splicing and expression of genes involved in inner ear development, auditory hair cell differentiation, and cell fate specification in the cochlear epithelium., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0016604 nuclear body;GO:1990904 ribonucleoprotein complex;GO:0005634 nucleus", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0043484 regulation of RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZV42-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZV43-1", "uniprot_id": [ { "id": "A0A286ZV43_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZV43", "type": "external" } ], "mass": 34645.0, "length": 334, "protein_name": "Zinc transporter ZIP11", "gene_name": "SLC39A11", "organism": "Pig", "refseq_name": "zinc transporter ZIP11 isoform X2", "refseq_ac": [ { "id": "XP_020922362", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922362", "type": "external" } ], "gene_names_uniprotkb": "SLC39A11", "gene_names_refseq": "SLC39A11", "protein_names_uniprotkb": "Zinc transporter ZIP11; Solute carrier family 39 member 11; Zrt- and Irt-like protein 11", "protein_names_refseq": "zinc transporter ZIP11 isoform X2", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A5K1UL96", "ec_number_list": [], "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity;GO:0005375 copper ion transmembrane transporter activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0071577 zinc ion transmembrane transport;GO:0071578 zinc ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZV43-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZV69-1", "uniprot_id": [ { "id": "A0A286ZV69_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZV69", "type": "external" } ], "mass": 37188.0, "length": 333, "protein_name": "Olfactory receptor family 10 subfamily D member 5", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor family 10 subfamily D member 5", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZV69-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZV96-1", "uniprot_id": [ { "id": "A0A286ZV96_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZV96", "type": "external" } ], "mass": 17014.0, "length": 147, "protein_name": "ECRG4 augurin", "gene_name": "ECRG4", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ECRG4", "gene_names_refseq": "", "protein_names_uniprotkb": "ECRG4 augurin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0042127 regulation of cell population proliferation;GO:0007417 central nervous system development;GO:0031145 anaphase-promoting complex-dependent catabolic process;GO:0090398 cellular senescence;GO:0070314 G1 to G0 transition", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZV96-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZVC7-1", "uniprot_id": [ { "id": "A0A286ZVC7_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZVC7", "type": "external" } ], "mass": 86865.0, "length": 760, "protein_name": "General transcription and DNA repair factor IIH helicase subunit XPD", "gene_name": "ERCC2", "organism": "Pig", "refseq_name": "TFIIH basal transcription factor complex helicase XPD subunit isoform X1", "refseq_ac": [ { "id": "XP_020950204", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020950204", "type": "external" } ], "gene_names_uniprotkb": "ERCC2", "gene_names_refseq": "ERCC2", "protein_names_uniprotkb": "General transcription and DNA repair factor IIH helicase subunit XPD; 5.6.2.3; CXPD; DNA 5'-3' helicase XPD; DNA excision repair protein ERCC-2; DNA repair protein complementing XP-D cells; Xeroderma pigmentosum group D-complementing protein", "protein_names_refseq": "TFIIH basal transcription factor complex helicase XPD subunit isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100049685); (R-SSC-112382); (R-SSC-113418); (R-SSC-5696395); (R-SSC-5696400); (R-SSC-674695); (R-SSC-6781823); (R-SSC-6782135); (R-SSC-6782210); (R-SSC-6796648); (R-SSC-72086); (R-SSC-73762); (R-SSC-73772); (R-SSC-73776); (R-SSC-73779); (R-SSC-73863); (R-SSC-75953); (R-SSC-75955); (R-SSC-76042); (R-SSC-77075)", "pathway_count": 20, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287AG01", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0003684 damaged DNA binding;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0071817 MMXD complex;GO:0005675 transcription factor TFIIH holo complex;GO:0005669 transcription factor TFIID complex", "go_biological_process": "GO:0007059 chromosome segregation;GO:0006366 transcription by RNA polymerase II;GO:0006289 nucleotide-excision repair;GO:0035315 hair cell differentiation;GO:0045951 positive regulation of mitotic recombination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZVC7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "uniprot_id": [ { "id": "A0A286ZVC9_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZVC9", "type": "external" } ], "mass": 35908.0, "length": 320, "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "organism": "Pig", "refseq_name": "olfactory receptor 2W1-like", "refseq_ac": [ { "id": "XP_020937345", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937345", "type": "external" } ], "gene_names_uniprotkb": "LOC110258401; LOC110258164", "gene_names_refseq": "LOC110258401", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 2W1-like", "tax_id": 9823, "disease": "", "pathway": " (ssc:110258401)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZVC9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZVF7-1", "uniprot_id": [ { "id": "A0A286ZVF7_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZVF7", "type": "external" } ], "mass": 46139.0, "length": 422, "protein_name": "selenide, water dikinase", "gene_name": "SEPHS1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SEPHS1", "gene_names_refseq": "", "protein_names_uniprotkb": "selenide, water dikinase; 2.7.9.3; Selenium donor protein 1; Selenophosphate synthase 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Core component of the zincore complex, a heterotetramer that acts as a molecular 'grip' to stabilize transcription factors at DNA-binding sites across the genome, thereby controlling gene expression. The zincore complex binds specifically to zinc finger transcription factors, such as ZFP91, ZNF652, ZNF526 and PRDM15, and stabilizes them onto their cognate DNA motif. Within the complex, SEPHS1, recognizes and binds the backbone of zinc fingers of transcription factors in a sequence-independent manner via its arginine clamp, enhancing their DNA-binding stability. Plays an essential role in redox homeostasis. May also be involved in selenocysteine biosynthesis by catalyzing formation of selenophosphate from selenide and ATP. Its role in selenocysteine biosynthesis is however unclear and several studies suggest that it does not act as a selenophosphate synthase in vivo or plays an non-essential role. Required for cardiac differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004756 selenide, water dikinase activity;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0031965 nuclear membrane", "go_biological_process": "GO:0016260 selenocysteine biosynthetic process;GO:0045454 cell redox homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZVF7-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZVH1-1", "uniprot_id": [ { "id": "A0A286ZVH1_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZVH1", "type": "external" } ], "mass": 58164.0, "length": 530, "protein_name": "Solute carrier family 2 member 9", "gene_name": "SLC2A9", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SLC2A9", "gene_names_refseq": "", "protein_names_uniprotkb": "Solute carrier family 2 member 9", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-189200)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005353 fructose transmembrane transporter activity;GO:0015143 urate transmembrane transporter activity;GO:0055056 D-glucose transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0070837 dehydroascorbic acid transport;GO:1904659 D-glucose transmembrane transport;GO:0046415 urate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZVH1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZVI6-1", "uniprot_id": [ { "id": "A0A286ZVI6_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZVI6", "type": "external" } ], "mass": 135776.0, "length": 1240, "protein_name": "SAM and SH3 domain-containing protein 1", "gene_name": "SASH1", "organism": "Pig", "refseq_name": "SAM and SH3 domain-containing protein 1 isoform X5", "refseq_ac": [ { "id": "XP_020927728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020927728", "type": "external" } ], "gene_names_uniprotkb": "SASH1", "gene_names_refseq": "SASH1", "protein_names_uniprotkb": "SAM and SH3 domain-containing protein 1", "protein_names_refseq": "SAM and SH3 domain-containing protein 1 isoform X5", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Is a positive regulator of NF-kappa-B signaling downstream of TLR4 activation. It acts as a scaffold molecule to assemble a molecular complex that includes TRAF6, MAP3K7, CHUK and IKBKB, thereby facilitating NF-kappa-B signaling activation. Regulates TRAF6 and MAP3K7 ubiquitination. Involved in the regulation of cell mobility. Regulates lipolysaccharide (LPS)-induced endothelial cell migration. Is involved in the regulation of skin pigmentation through the control of melanocyte migration in the epidermis., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0001965 G-protein alpha-subunit binding;GO:0031435 mitogen-activated protein kinase kinase kinase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0032991 protein-containing complex", "go_biological_process": "GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction;GO:0010632 regulation of epithelial cell migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZVI6-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZVK9-1", "uniprot_id": [ { "id": "A0A286ZVK9_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZVK9", "type": "external" } ], "mass": 17778.0, "length": 165, "protein_name": "Cytosolic iron-sulfur assembly component 2B", "gene_name": "CIAO2B", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CIAO2B", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytosolic iron-sulfur assembly component 2B; Mitotic spindle-associated MMXD complex subunit MIP18", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As a CIA complex component and in collaboration with CIAO1 and MMS19, binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Together with MMS19, facilitates the transfer of Fe-S clusters to the motor protein KIF4A, which ensures proper localization of KIF4A to mitotic machinery components to promote the progression of mitosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, 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"https://www.uniprot.org/uniprot/A0A286ZVL1", "type": "external" } ], "mass": 31773.0, "length": 279, "protein_name": "Thioredoxin-related transmembrane protein 1", "gene_name": "TMX1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TMX1", "gene_names_refseq": "", "protein_names_uniprotkb": "Thioredoxin-related transmembrane protein 1; 5.3.4.1; Protein disulfide-isomerase TMX1; Thioredoxin domain-containing protein 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100152543)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015036 disulfide oxidoreductase activity;GO:0004857 enzyme inhibitor activity;GO:0015035 protein-disulfide reductase activity;GO:0003756 protein disulfide isomerase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005730 nucleolus;GO:0031966 mitochondrial membrane;GO:0005789 endoplasmic reticulum membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0051924 regulation of calcium ion transport;GO:0034976 response to endoplasmic reticulum stress;GO:1904294 positive regulation of ERAD pathway;GO:0010868 negative regulation of triglyceride biosynthetic process;GO:0090331 negative regulation of platelet aggregation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZVL1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZVL5-1", "uniprot_id": [ { "id": "A0A286ZVL5_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZVL5", "type": "external" } ], "mass": 82242.0, "length": 718, "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", 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The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031681 G-protein beta-subunit binding", "go_cellular_component": "GO:0045202 synapse;GO:0005834 heterotrimeric G-protein complex", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0030308 negative regulation of cell growth", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZVN4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZVQ7-1", "uniprot_id": [ { "id": "A0A286ZVQ7_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZVQ7", "type": "external" } ], "mass": 36200.0, "length": 328, "protein_name": "Olfactory receptor", "gene_name": "LOC110257987", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC110257987", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZVQ7-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZVQ9-1", "uniprot_id": [ { "id": "A0A286ZVQ9_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZVQ9", "type": "external" } ], "mass": 35868.0, "length": 312, "protein_name": "Taste receptor type 2", "gene_name": "TAS2R7", "organism": "Pig", "refseq_name": "taste receptor type 2 member 7", "refseq_ac": [ { "id": "XP_003126548", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126548", "type": "external" } ], "gene_names_uniprotkb": "TAS2R7", "gene_names_refseq": "TAS2R7", "protein_names_uniprotkb": "Taste receptor type 2", "protein_names_refseq": "taste receptor type 2 member 7", "tax_id": 9823, "disease": "", "pathway": " (ssc:100523246); 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Suppresses insulin-induced promoter activities through AP1 and SRE. 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"uniprot_canonical_ac": "A0A286ZW31-1", "uniprot_id": [ { "id": "A0A286ZW31_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZW31", "type": "external" } ], "mass": 38705.0, "length": 337, "protein_name": "Neurogenic differentiation factor", "gene_name": "NEUROD6", "organism": "Pig", "refseq_name": "neurogenic differentiation factor 6", "refseq_ac": [ { "id": "XP_020934874", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020934874", "type": "external" } ], "gene_names_uniprotkb": "NEUROD6", "gene_names_refseq": "NEUROD6", "protein_names_uniprotkb": "Neurogenic differentiation factor", "protein_names_refseq": "neurogenic differentiation factor 6", "tax_id": 9823, "disease": "", "pathway": " (ssc:110257619)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0070888 E-box binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0061564 axon development;GO:0007423 sensory organ development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZW31-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZW50-1", "uniprot_id": [ { "id": "A0A286ZW50_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZW50", "type": "external" } ], "mass": 34567.0, "length": 311, "protein_name": "Olfactory receptor", "gene_name": "", "organism": "Pig", "refseq_name": "olfactory receptor 8G1-like", "refseq_ac": [ { "id": "XP_003130048", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130048", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "LOC100516990", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 8G1-like", "tax_id": 9823, "disease": "", "pathway": " (ssc:100516990)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZW50-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZW63-1", "uniprot_id": [ { "id": "A0A286ZW63_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZW63", "type": "external" } ], "mass": 22631.0, "length": 204, "protein_name": "Ephrin-A4", "gene_name": "EFNA4", "organism": "Pig", "refseq_name": "ephrin-A4 isoform X1", "refseq_ac": [ { "id": "XP_001929361", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929361", "type": "external" } ], "gene_names_uniprotkb": "EFNA4", "gene_names_refseq": "EFNA4", "protein_names_uniprotkb": "Ephrin-A4; EPH-related receptor tyrosine kinase ligand 4", "protein_names_refseq": "ephrin-A4 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100154710); (R-SSC-2682334); (R-SSC-3928663); (R-SSC-3928665)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046875 ephrin receptor binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "GO:0048013 ephrin receptor signaling pathway;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZW63-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZW78-1", "uniprot_id": [ { "id": "A0A286ZW78_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZW78", "type": "external" } ], "mass": 74332.0, "length": 654, "protein_name": "Protein SERAC1", "gene_name": "SERAC1", "organism": "Pig", "refseq_name": "protein SERAC1 isoform X2", "refseq_ac": [ { "id": "XP_005654409", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654409", "type": "external" } ], "gene_names_uniprotkb": "SERAC1", "gene_names_refseq": "SERAC1", "protein_names_uniprotkb": "Protein SERAC1; Serine active site-containing protein 1", "protein_names_refseq": "protein SERAC1 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100523935)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Facilitates the transport of serine from the cytosol to the mitochondria by interacting with and stabilizing Sideroflexin-1 (SFXN1), a mitochondrial serine transporter, playing a fundamental role in the one-carbon cycle responsible for the synthesis of nucleotides needed for mitochondrial DNA replication. Plays an important role in the phosphatidylglycerol (PG) remodeling that is essential for both mitochondrial function and intracellular cholesterol trafficking. Specifically involved in the exchange of the sn-1 acyl chain from PG 16:0/18:1(9Z) (also known as 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)) to PG 18:0/18:1(9Z) (also known as 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)), a step needed in the bis(monoacylglycerol)phosphate biosynthetic pathway. May have acyltransferase activity although the mechanism for PG remodeling has not been determined., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0031012 extracellular matrix;GO:0005789 endoplasmic reticulum membrane;GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site;GO:0005739 mitochondrion", "go_biological_process": "GO:0036148 phosphatidylglycerol acyl-chain remodeling;GO:0032367 intracellular cholesterol transport;GO:0008654 phospholipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZW78-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZW96-1", "uniprot_id": [ { "id": "A0A286ZW96_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZW96", "type": "external" } ], "mass": 35560.0, "length": 333, "protein_name": "SIX homeobox 3", "gene_name": "SIX3", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SIX3", "gene_names_refseq": "", "protein_names_uniprotkb": "SIX homeobox 3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, 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corepressor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0014016 neuroblast differentiation;GO:1990086 lens fiber cell apoptotic process;GO:0061074 regulation of neural retina development;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045665 negative regulation of neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZW96-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZWA5-1", "uniprot_id": [ { "id": "A0A286ZWA5_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZWA5", "type": "external" } ], "mass": 58089.0, "length": 547, "protein_name": "Ubiquilin 2", "gene_name": "UBQLN2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "UBQLN2", "gene_names_refseq": "", "protein_names_uniprotkb": 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"reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031593 polyubiquitin modification-dependent protein binding;GO:0042802 identical protein binding;GO:0140693 molecular condensate scaffold activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0016020 membrane;GO:0031410 cytoplasmic vesicle;GO:0005776 autophagosome", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0016241 regulation of macroautophagy;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0036503 ERAD pathway;GO:1904294 positive regulation of ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZWA5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZWA9-1", "uniprot_id": [ { "id": "A0A286ZWA9_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZWA9", "type": "external" } ], "mass": 193134.0, "length": 1689, "protein_name": "E3 ubiquitin-protein ligase SHPRH", "gene_name": "SHPRH", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SHPRH", "gene_names_refseq": "", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase SHPRH; 2.3.2.27; RING-type E3 ubiquitin transferase SHPRH; SNF2, histone-linker, PHD and RING finger domain-containing helicase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, 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CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. 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Pleckstrin homology domain-containing family K member 1", "protein_names_refseq": "rhotekin-2 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100157770)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0035556 intracellular signal transduction;GO:0002250 adaptive immune response;GO:0030097 hemopoiesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZWI9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZWJ2-1", "uniprot_id": [ { "id": "A0A286ZWJ2_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZWJ2", "type": "external" } ], "mass": 19726.0, "length": 174, "protein_name": "Eukaryotic translation elongation factor 1 epsilon-1", "gene_name": "EEF1E1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "EEF1E1", "gene_names_refseq": "", "protein_names_uniprotkb": "Eukaryotic translation elongation factor 1 epsilon-1; 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The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids. Also has weak activity for CMP. UMP and purine nucleotides are poor substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, 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"", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZWU1-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZWU9-1", "uniprot_id": [ { "id": "A0A286ZWU9_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZWU9", "type": "external" } ], "mass": 34757.0, "length": 312, "protein_name": "Malectin", "gene_name": "MLEC", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "MLEC", "gene_names_refseq": "", "protein_names_uniprotkb": "Malectin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-6798695)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, 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"record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZWV4-1", "uniprot_id": [ { "id": "A0A286ZWV4_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZWV4", "type": "external" } ], "mass": 55010.0, "length": 479, "protein_name": "2-phosphoxylose phosphatase 1", "gene_name": "PXYLP1", "organism": "Pig", "refseq_name": "2-phosphoxylose phosphatase 1 isoform X1", "refseq_ac": [ { "id": "XP_013837544", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013837544", "type": "external" } ], "gene_names_uniprotkb": "PXYLP1", "gene_names_refseq": "PXYLP1", "protein_names_uniprotkb": "2-phosphoxylose phosphatase 1; Acid phosphatase-like protein 2", "protein_names_refseq": "2-phosphoxylose phosphatase 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100515055); (R-SSC-1971475)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1TE40", "ec_number_list": [], "go_molecular_function": "GO:0016791 phosphatase activity;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0006024 glycosaminoglycan biosynthetic process;GO:0050650 chondroitin sulfate proteoglycan biosynthetic process;GO:0010909 positive regulation of heparan sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZWV4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZWV8-1", "uniprot_id": [ { "id": "A0A286ZWV8_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZWV8", "type": "external" } ], "mass": 98384.0, "length": 881, "protein_name": "Oxysterol-binding protein", "gene_name": "OSBPL5", "organism": "Pig", "refseq_name": "oxysterol-binding protein-related protein 5 isoform X2", "refseq_ac": [ { "id": "XP_020938298", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938298", "type": "external" } ], "gene_names_uniprotkb": "OSBPL5", "gene_names_refseq": "OSBPL5", "protein_names_uniprotkb": "Oxysterol-binding protein", "protein_names_refseq": "oxysterol-binding protein-related protein 5 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1482801)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane: specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds phosphatidylserine and PI4P in a mutually exclusive manner. May cooperate with NPC1 to mediate the exit of cholesterol from endosomes/lysosomes. Binds 25-hydroxycholesterol and cholesterol., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, 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"kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZWX5-1", "uniprot_id": [ { "id": "A0A286ZWX5_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZWX5", "type": "external" } ], "mass": 10780.0, "length": 88, "protein_name": "Meiosis/spermiosis associated 1", "gene_name": "MEIG1", "organism": "Pig", "refseq_name": "meiosis/spermiogenesis associated 1", "refseq_ac": [ { "id": "NP_001422196", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422196", "type": "external" } ], "gene_names_uniprotkb": "MEIG1", "gene_names_refseq": "MEIG1", "protein_names_uniprotkb": "Meiosis/spermiosis associated 1", "protein_names_refseq": "meiosis/spermiogenesis associated 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100626847)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Essential for spermiogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, 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"secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0002177 manchette", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZWX5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZWZ6-1", "uniprot_id": [ { "id": "A0A286ZWZ6_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZWZ6", "type": "external" } ], "mass": 124113.0, "length": 1134, "protein_name": "Protocadherin Fat 3", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Protocadherin Fat 3; FAT tumor suppressor homolog 3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "May play a role in the interactions between neurites derived from specific subsets of neurons during development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, 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"A0A286ZWZ7_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZWZ7", "type": "external" } ], "mass": 168549.0, "length": 1507, "protein_name": "Gem-associated protein 5", "gene_name": "GEMIN5", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "GEMIN5", "gene_names_refseq": "", "protein_names_uniprotkb": "Gem-associated protein 5", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-191859)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030621 U4 snRNA binding;GO:0043022 ribosome binding;GO:0000340 RNA 7-methylguanosine cap binding;GO:0003730 mRNA 3'-UTR binding;GO:0030622 U4atac snRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0032797 SMN complex;GO:0034718 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May play a role in mitochondrial protein synthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A286ZXA6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZXB4-1", "uniprot_id": [ { "id": "A0A286ZXB4_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZXB4", "type": "external" } ], "mass": 92916.0, "length": 840, "protein_name": "Low-density lipoprotein receptor-related protein 12", "gene_name": "LRP12", "organism": "Pig", "refseq_name": "low-density lipoprotein receptor-related protein 12 isoform X1", "refseq_ac": [ { "id": "XP_003125579", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125579", "type": "external" } ], "gene_names_uniprotkb": "LRP12", "gene_names_refseq": "LRP12", "protein_names_uniprotkb": "Low-density lipoprotein receptor-related protein 12", "protein_names_refseq": "low-density lipoprotein receptor-related protein 12 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-975634)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1S1E8", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit", "go_biological_process": "GO:0006897 endocytosis;GO:0031175 neuron projection development;GO:0001764 neuron migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZXB4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZXB5-1", "uniprot_id": [ { "id": "A0A286ZXB5_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZXB5", "type": "external" } ], "mass": 35359.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "LOC110258933", "organism": "Pig", "refseq_name": "olfactory receptor 12D3-like", "refseq_ac": [ { "id": "XP_020937877", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937877", "type": "external" } ], "gene_names_uniprotkb": "LOC110258933", "gene_names_refseq": "LOC110258933", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 12D3-like", "tax_id": 9823, "disease": "", "pathway": " (ssc:110258933)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZXB5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZW86-1", "uniprot_id": [ { "id": "A0A286ZW86_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZW86", "type": "external" } ], "mass": 17105.0, "length": 146, "protein_name": "Caveolin", "gene_name": "CAV1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CAV1", "gene_names_refseq": "", "protein_names_uniprotkb": "Caveolin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-203615); (R-SSC-203641); (R-SSC-209968); (R-SSC-4641262); (R-SSC-8980692); (R-SSC-9009391); (R-SSC-9013026); (R-SSC-9013106); (R-SSC-9013148); (R-SSC-9013149); (R-SSC-9013404); (R-SSC-9013406); (R-SSC-9013407); (R-SSC-9013408); (R-SSC-9013423); (R-SSC-9035034); (R-SSC-9696264); (R-SSC-9696270); (R-SSC-9696273)", "pathway_count": 19, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway. Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation. Binds 20(S)-hydroxycholesterol (20(S)-OHC)., [UniProtKB, UniProtKB, UniProtKB]; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070320 inward rectifier potassium channel inhibitor activity;GO:0060090 molecular adaptor activity;GO:0008142 oxysterol binding;GO:0005102 signaling receptor binding;GO:0016504 peptidase activator activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005768 endosome;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005925 focal adhesion", "go_biological_process": "GO:0048550 negative regulation of pinocytosis;GO:0072584 caveolin-mediated endocytosis;GO:1900027 regulation of ruffle assembly;GO:2000535 regulation of entry of bacterium into host cell;GO:1901380 negative regulation of potassium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZW86-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZNN3-1", "uniprot_id": [ { "id": "A0A286ZNN3_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZNN3", "type": "external" } ], "mass": 85393.0, "length": 780, "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "HGS", "gene_names_refseq": "", "protein_names_uniprotkb": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-182971); (R-SSC-432720); (R-SSC-5689880); (R-SSC-6807004); (R-SSC-8856825); (R-SSC-8856828); (R-SSC-9013420); (R-SSC-917729)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin-coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. May contribute to the efficient recruitment of SMADs to the activin receptor complex. Involved in receptor recycling via its association with the CART complex, a multiprotein complex required for efficient transferrin receptor recycling but not for EGFR degradation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019904 protein domain specific binding;GO:0035091 phosphatidylinositol binding;GO:0043130 ubiquitin binding;GO:0044389 ubiquitin-like protein ligase binding", "go_cellular_component": "GO:0031901 early endosome membrane;GO:0032585 multivesicular body membrane;GO:0033565 ESCRT-0 complex;GO:0005769 early endosome;GO:0005829 cytosol", "go_biological_process": "GO:0015031 protein transport;GO:0010324 membrane invagination;GO:0010628 positive regulation of gene expression;GO:0031623 receptor internalization;GO:0016525 negative regulation of angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZNN3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZYV1-1", "uniprot_id": [ { "id": "A0A286ZYV1_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZYV1", "type": "external" } ], "mass": 71067.0, "length": 604, "protein_name": "Radixin", "gene_name": "RDX", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "RDX", "gene_names_refseq": "", "protein_names_uniprotkb": "Radixin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1TKB2", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0019904 protein domain specific binding;GO:0051117 ATPase binding;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005902 microvillus;GO:0005912 adherens junction;GO:0005925 focal adhesion", "go_biological_process": "GO:1902966 positive regulation of protein localization to early endosome;GO:0061028 establishment of endothelial barrier;GO:1902115 regulation of organelle assembly;GO:0010628 positive regulation of gene expression;GO:0072659 protein localization to plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZYV1-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A4Q7-1", "uniprot_id": [ { "id": "A0A287A4Q7_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A4Q7", "type": "external" } ], "mass": 104377.0, "length": 906, "protein_name": "F-actin cross-linking protein", "gene_name": "ACTN4", "organism": "Pig", "refseq_name": "alpha-actinin-4 isoform X5", "refseq_ac": [ { "id": "XP_003355932", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003355932", "type": "external" } ], "gene_names_uniprotkb": "ACTN4", "gene_names_refseq": "ACTN4", "protein_names_uniprotkb": "F-actin cross-linking protein", "protein_names_refseq": "alpha-actinin-4 isoform X5", "tax_id": 9823, "disease": "", "pathway": " (ssc:100517284); (R-SSC-114608)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0005509 calcium ion binding;GO:0003713 transcription coactivator activity;GO:0042803 protein homodimerization activity;GO:0051015 actin filament binding", "go_cellular_component": "GO:0030018 Z disc;GO:0005768 endosome;GO:0098871 postsynaptic actin cytoskeleton;GO:0005634 nucleus;GO:0005886 plasma membrane", "go_biological_process": "GO:0030335 positive regulation of cell migration;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction;GO:0030036 actin cytoskeleton organization;GO:0048384 retinoic acid receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A4Q7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZZD9-1", "uniprot_id": [ { "id": "A0A286ZZD9_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZZD9", "type": "external" } ], "mass": 20851.0, "length": 189, "protein_name": "RAB2A, member RAS onco family", "gene_name": "RAB2A", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": 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"refseq_ac": [ { "id": "XP_003356390", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003356390", "type": "external" } ], "gene_names_uniprotkb": "PSMG2", "gene_names_refseq": "PSMG2", "protein_names_uniprotkb": "Proteasome assembly chaperone 2", "protein_names_refseq": "proteasome assembly chaperone 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100622916); (R-SSC-9907900)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0043248 proteasome assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZXX4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZXX5-1", "uniprot_id": [ { "id": "A0A286ZXX5_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZXX5", "type": "external" } ], "mass": 34259.0, "length": 301, "protein_name": "Phosducin-like protein", "gene_name": "PDCL", "organism": "Pig", "refseq_name": "phosducin-like protein", "refseq_ac": [ { "id": "XP_001927731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927731", "type": "external" } ], "gene_names_uniprotkb": "PDCL", "gene_names_refseq": "PDCL", "protein_names_uniprotkb": "Phosducin-like protein", "protein_names_refseq": "phosducin-like protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:100153625); (R-SSC-6814122)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005929 cilium", "go_biological_process": "GO:0007601 visual perception;GO:0030030 cell projection organization;GO:1902605 heterotrimeric G-protein complex assembly;GO:0008277 regulation of G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZXX5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZXX9-1", "uniprot_id": [ { "id": "A0A286ZXX9_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZXX9", "type": "external" } ], "mass": 30657.0, "length": 275, "protein_name": "GIY-YIG domain-containing protein", "gene_name": "SLX1A", "organism": "Pig", "refseq_name": "structure-specific endonuclease subunit SLX1", "refseq_ac": [ { "id": "XP_020943694", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020943694", "type": "external" } ], "gene_names_uniprotkb": "SLX1A", "gene_names_refseq": "SLX1A", "protein_names_uniprotkb": "GIY-YIG domain-containing protein", "protein_names_refseq": "structure-specific endonuclease subunit SLX1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100621669); (R-SSC-5693568); (R-SSC-6783310)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008821 crossover junction DNA endonuclease activity;GO:0017108 5'-flap endonuclease activity", "go_cellular_component": "GO:0033557 Slx1-Slx4 complex", "go_biological_process": "GO:1904431 positive regulation of t-circle formation;GO:0000724 double-strand break repair via homologous recombination;GO:0090656 t-circle formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZXX9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZXY0-1", "uniprot_id": [ { "id": "A0A286ZXY0_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZXY0", "type": "external" } ], "mass": 15062.0, "length": 139, "protein_name": "Transmembrane protein 14C", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Transmembrane protein 14C", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Required for normal heme biosynthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0006783 heme biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZXY0-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZXY5-1", "uniprot_id": [ { "id": "A0A286ZXY5_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZXY5", "type": "external" } ], "mass": 97476.0, "length": 882, "protein_name": "Nuclear valosin-containing protein-like", "gene_name": "NVL", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "NVL", "gene_names_refseq": "", "protein_names_uniprotkb": "Nuclear valosin-containing protein-like", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Participates in the assembly of the telomerase holoenzyme and effecting of telomerase activity via its interaction with TERT. Involved in both early and late stages of the pre-rRNA processing pathways. Spatiotemporally regulates 60S ribosomal subunit biogenesis in the nucleolus. Catalyzes the release of specific assembly factors, such as WDR74, from pre-60S ribosomal particles through the ATPase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990275 preribosome binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0000176 nuclear exosome (RNase complex);GO:0005697 telomerase holoenzyme complex", "go_biological_process": "GO:0042273 ribosomal large subunit biogenesis;GO:0042254 ribosome biogenesis;GO:0006364 rRNA processing;GO:1905323 telomerase holoenzyme complex assembly;GO:1904749 regulation of protein localization to nucleolus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZXY5-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZY04-1", "uniprot_id": [ { "id": "A0A286ZY04_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZY04", "type": "external" } ], "mass": 76398.0, "length": 714, "protein_name": "Leucine rich repeat containing 4B", "gene_name": "LRRC4B", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LRRC4B", "gene_names_refseq": "", "protein_names_uniprotkb": "Leucine rich repeat containing 4B", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-388844)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0098632 cell-cell adhesion mediator activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005886 plasma membrane;GO:0044300 cerebellar mossy fiber;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:0051965 positive regulation of synapse assembly;GO:0099560 synaptic membrane adhesion;GO:1905606 regulation of presynapse assembly;GO:0099151 regulation of postsynaptic density assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZY04-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZY08-1", "uniprot_id": [ { "id": "A0A286ZY08_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZY08", "type": "external" } ], "mass": 36562.0, "length": 315, "protein_name": "RNA/RNP complex-1-interacting phosphatase", "gene_name": "DUSP11", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "DUSP11", "gene_names_refseq": "", "protein_names_uniprotkb": "RNA/RNP complex-1-interacting phosphatase; Dual specificity protein phosphatase 11; Phosphatase that interacts with RNA/RNP complex 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Possesses RNA 5'-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. In addition, has phosphatase activity with ATP, ADP and O-methylfluorescein phosphate (in vitro). Binds to RNA. May participate in nuclear mRNA metabolism., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0004651 polynucleotide 5'-phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0016607 nuclear speck", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZY08-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZY25-1", "uniprot_id": [ { "id": "A0A286ZY25_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZY25", "type": "external" } ], "mass": 120931.0, "length": 1102, "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 10", "gene_name": "ADAMTS10", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ADAMTS10", "gene_names_refseq": "", "protein_names_uniprotkb": "A disintegrin and metalloproteinase with thrombospondin motifs 10", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5173214)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Metalloprotease that participate in microfibrils assembly. 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6.3.5.2; GMP synthetase; Glutamine amidotransferase", "protein_names_refseq": "GMP synthase [glutamine-hydrolyzing] isoform X2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100512255); (R-SSC-73817); (R-SSC-9748787)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0003921 GMP synthase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006177 GMP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZY37-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZY44-1", "uniprot_id": [ { "id": "A0A286ZY44_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZY44", "type": "external" } ], "mass": 79709.0, "length": 701, "protein_name": "CLPTM1 regulator of GABA type A receptor forward trafficking", "gene_name": "CLPTM1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CLPTM1", "gene_names_refseq": "", "protein_names_uniprotkb": "CLPTM1 regulator of GABA type A receptor forward trafficking", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0050811 GABA receptor binding", "go_cellular_component": "GO:0016020 membrane;GO:0009897 external side of plasma membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0033081 regulation of T cell differentiation in thymus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZY44-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZY45-1", "uniprot_id": [ { "id": "A0A286ZY45_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZY45", "type": "external" } ], "mass": 56521.0, "length": 507, "protein_name": "Caspase-2", "gene_name": "CASP2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CASP2", "gene_names_refseq": "", "protein_names_uniprotkb": "Caspase-2; 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Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051117 ATPase binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0002028 regulation of sodium ion transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZY57-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZY62-1", "uniprot_id": [ { "id": "A0A286ZY62_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZY62", "type": "external" } ], "mass": 73890.0, "length": 659, "protein_name": "Mediator of RNA polymerase II transcription subunit 17", "gene_name": "MED17", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "MED17", "gene_names_refseq": "", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 17; Mediator complex subunit 17", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-9841922)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0046966 nuclear thyroid hormone receptor binding;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0016592 mediator complex;GO:0070847 core mediator complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZY62-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZYA1-1", "uniprot_id": [ { "id": "A0A286ZYA1_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZYA1", "type": "external" } ], "mass": 16736.0, "length": 148, "protein_name": "Arginine vasopressin-induced protein 1", "gene_name": "AVPI1", "organism": "Pig", "refseq_name": "arginine vasopressin-induced protein 1", "refseq_ac": [ { "id": "XP_001929094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929094", "type": "external" } ], "gene_names_uniprotkb": "AVPI1", "gene_names_refseq": "AVPI1", "protein_names_uniprotkb": "Arginine vasopressin-induced protein 1", "protein_names_refseq": "arginine vasopressin-induced protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100155615)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "May be involved in MAP kinase activation, epithelial sodium channel (ENaC) down-regulation and cell cycling., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1U7V0", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0043410 positive regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZYA1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZYB0-1", "uniprot_id": [ { "id": "A0A286ZYB0_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZYB0", "type": "external" } ], "mass": 77581.0, "length": 712, "protein_name": "Malonate--CoA ligase ACSF3, mitochondrial", "gene_name": "ACSF3", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ACSF3", "gene_names_refseq": "", "protein_names_uniprotkb": "Malonate--CoA ligase ACSF3, mitochondrial; 6.2.1.76; Acyl-CoA synthetase family member 3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-75876)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the initial reaction in intramitochondrial fatty acid synthesis, by activating malonate and methylmalonate, but not acetate, into their respective CoA thioester. May have some preference toward very-long-chain substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031957 very long-chain fatty acid-CoA ligase activity;GO:0016405 CoA-ligase activity;GO:0090409 malonyl-CoA synthetase activity;GO:0016874 ligase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005737 cytoplasm", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0090410 malonate catabolic process;GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZYB0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZYB5-1", "uniprot_id": [ { "id": "A0A286ZYB5_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZYB5", "type": "external" } ], "mass": 24443.0, "length": 224, "protein_name": "Deoxyuridine 5'-triphosphate nucleotidohydrolase", "gene_name": "DUT", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "DUT", "gene_names_refseq": "", "protein_names_uniprotkb": "Deoxyuridine 5'-triphosphate nucleotidohydrolase; 3.6.1.23; dUTP pyrophosphatase; dUTPase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-499943)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the cleavage of 2'-deoxyuridine 5'-triphosphate (dUTP) into 2'-deoxyuridine 5'-monophosphate (dUMP) and inorganic pyrophosphate and through its action efficiently prevents uracil misincorporation into DNA and at the same time provides dUMP, the substrate for de novo thymidylate biosynthesis. Inhibits peroxisome proliferator-activated receptor (PPAR) activity by binding of its N-terminal to PPAR, preventing the latter's dimerization with retinoid X receptor. Essential for embryonic development., [UniProtKB, UniProtKB, UniProtKB]; Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004170 dUTP diphosphatase activity", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0006226 dUMP biosynthetic process;GO:0006231 dTMP biosynthetic process;GO:0046081 dUTP catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZYB5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZYB8-1", "uniprot_id": [ { "id": "A0A286ZYB8_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZYB8", "type": "external" } ], "mass": 50935.0, "length": 478, "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "organism": "Pig", "refseq_name": "OTU domain-containing protein 1", "refseq_ac": [ { "id": "XP_020920576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920576", "type": "external" } ], "gene_names_uniprotkb": "OTUD1", "gene_names_refseq": "OTUD1", "protein_names_uniprotkb": "OTU domain-containing protein 1; 3.4.19.12", "protein_names_refseq": "OTU domain-containing protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:106504170); (R-SSC-5357786); (R-SSC-5357905); (R-SSC-5357956)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Deubiquitinating enzyme that specifically hydrolyzes 'Lys-63'-linked polyubiquitin to monoubiquitin. Required for the stability and translation of a subset mRNAs with a high abundance of rare codons by mediating deubiquitination of 40S ribosomal protein RPS10/eS10, thereby antagonizing ZNF598-mediated 40S ubiquitination. The abundance of rare codons in mRNAs can limit the translation rate and can lead to ribosome collisions that trigger activation of ribosome quality control (RQC) pathway by ZNF598. OTUD1-mediated deubiquitination prevents activation of the RQC and subsequent dissociation of ribosomes and stimulates formation of polysomes and translation., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "", "go_biological_process": "GO:0006508 proteolysis;GO:0070536 protein K63-linked deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZYB8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZYC2-1", "uniprot_id": [ { "id": "A0A286ZYC2_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZYC2", "type": "external" } ], "mass": 33854.0, "length": 300, "protein_name": "Olfactory receptor", "gene_name": "LOC110258521", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC110258521", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZYC2-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZYE7-1", "uniprot_id": [ { "id": "A0A286ZYE7_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZYE7", "type": "external" } ], "mass": 46393.0, "length": 420, "protein_name": "Heterogeneous nuclear ribonucleoprotein D-like", "gene_name": "HNRNPDL", "organism": "Pig", "refseq_name": "heterogeneous nuclear ribonucleoprotein D-like isoform X1", "refseq_ac": [ { "id": "XP_020957533", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020957533", "type": "external" } ], "gene_names_uniprotkb": "HNRNPDL", "gene_names_refseq": "HNRNPDL", "protein_names_uniprotkb": "Heterogeneous nuclear ribonucleoprotein D-like", "protein_names_refseq": "heterogeneous nuclear ribonucleoprotein D-like isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100511704)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes. Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter. Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers. Binds to the 5'-ACUAGC-3' RNA consensus sequence., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287B2L4", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0000785 chromatin;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZYE7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZYG1-1", "uniprot_id": [ { "id": "A0A286ZYG1_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZYG1", "type": "external" } ], "mass": 8221.0, "length": 72, "protein_name": "Large ribosomal subunit protein eL37", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Large ribosomal subunit protein eL37; 60S ribosomal protein L37", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-156827); (R-SSC-1799339); (R-SSC-6791226); (R-SSC-72689); (R-SSC-72706); (R-SSC-975956); (R-SSC-975957); (R-SSC-9954709); (R-SSC-9954714); (R-SSC-9954716)", "pathway_count": 10, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Component of the large ribosomal subunit. 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"reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005504 fatty acid binding;GO:0050660 flavin adenine dinucleotide binding;GO:0071949 FAD binding;GO:0003997 acyl-CoA oxidase activity", "go_cellular_component": "GO:0005777 peroxisome;GO:0005829 cytosol", "go_biological_process": "GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase;GO:0006631 fatty acid metabolic process;GO:0006635 fatty acid beta-oxidation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A1A8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A1B6-1", "uniprot_id": [ { "id": "A0A287A1B6_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A1B6", "type": "external" } ], "mass": 53469.0, "length": 453, "protein_name": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma", "gene_name": "PPP2R3C", "organism": "Pig", "refseq_name": "serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1", "refseq_ac": [ { "id": "XP_020954828", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954828", "type": "external" } ], "gene_names_uniprotkb": "PPP2R3C", "gene_names_refseq": "PPP2R3C", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma", "protein_names_refseq": "serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:110261574)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "May regulate MCM3AP phosphorylation through phosphatase recruitment. May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1T9V3", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0005813 centrosome;GO:0005829 cytosol;GO:0016604 nuclear body;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0035303 regulation of dephosphorylation;GO:0000226 microtubule cytoskeleton organization;GO:0043029 T cell homeostasis;GO:0001782 B cell homeostasis;GO:0045579 positive regulation of B cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A1B6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A1B8-1", "uniprot_id": [ { "id": "A0A287A1B8_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A1B8", "type": "external" } ], "mass": 86077.0, "length": 752, "protein_name": "Mitotic arrest deficient 1 like 1", "gene_name": "MAD1L1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "MAD1L1", "gene_names_refseq": "", "protein_names_uniprotkb": "Mitotic arrest deficient 1 like 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-141430); (R-SSC-141444); (R-SSC-2467813); (R-SSC-2500257); (R-SSC-5663220); (R-SSC-68877); (R-SSC-9648025)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Forms a heterotetrameric complex with the closed conformation form of MAD2L1 (C-MAD2) at unattached kinetochores during prometaphase, recruits an open conformation of MAD2L1 (O-MAD2) and promotes the conversion of O-MAD2 to C-MAD2, which ensures mitotic checkpoint signaling., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043515 kinetochore binding", "go_cellular_component": "GO:0044615 nuclear pore nuclear basket;GO:0005635 nuclear envelope;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0031965 nuclear membrane", "go_biological_process": "GO:0051315 attachment of mitotic spindle microtubules to kinetochore;GO:0090235 regulation of metaphase plate congression;GO:0051301 cell division;GO:0007094 mitotic spindle assembly checkpoint signaling;GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A1B8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A1C0-1", "uniprot_id": [ { "id": "A0A287A1C0_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A1C0", "type": "external" } ], "mass": 65912.0, "length": 625, "protein_name": "Dual specificity protein phosphatase 8", "gene_name": "DUSP8", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "DUSP8", "gene_names_refseq": "", "protein_names_uniprotkb": "Dual specificity protein phosphatase 8; 3.1.3.16; 3.1.3.48", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-112409); (R-SSC-5675221)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Has phosphatase activity with synthetic phosphatase substrates and negatively regulates mitogen-activated protein kinase activity, presumably by catalysing their dephosphorylation. Expected to display protein phosphatase activity toward phosphotyrosine, phosphoserine and phosphothreonine residues., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0008330 protein tyrosine/threonine phosphatase activity;GO:0033550 MAP kinase tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A1C0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A1C3-1", "uniprot_id": [ { "id": "A0A287A1C3_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A1C3", "type": "external" } ], "mass": 32058.0, "length": 287, "protein_name": "Programmed cell death 1", "gene_name": "PDCD1", "organism": "Pig", "refseq_name": "programmed cell death protein 1 isoform X1", "refseq_ac": [ { "id": "XP_020930289", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020930289", "type": "external" } ], "gene_names_uniprotkb": "PDCD1", "gene_names_refseq": "PDCD1", "protein_names_uniprotkb": "Programmed cell death 1", "protein_names_refseq": "programmed cell death protein 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-389948); (R-SSC-9931295)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0050776 regulation of immune response;GO:0050860 negative regulation of T cell receptor signaling pathway;GO:0050868 negative regulation of T cell activation;GO:0002841 negative regulation of T cell mediated immune response to tumor cell", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A1C3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A1D3-1", "uniprot_id": [ { "id": "A0A287A1D3_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A1D3", "type": "external" } ], "mass": 50689.0, "length": 440, "protein_name": "Glucoside xylosyltransferase 1", "gene_name": "GXYLT1", "organism": "Pig", "refseq_name": "glucoside xylosyltransferase 1 isoform X1", "refseq_ac": [ { "id": "XP_020948197", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020948197", "type": "external" } ], "gene_names_uniprotkb": "GXYLT1", "gene_names_refseq": "GXYLT1", "protein_names_uniprotkb": "Glucoside xylosyltransferase 1; 2.4.2.42; Glycosyltransferase 8 domain-containing protein 3", "protein_names_refseq": "glucoside xylosyltransferase 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:110260763)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, 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glycosylation via N-acetyl-galactosamine;GO:0180059 protein O-linked glycosylation via glucose", "synthesized_glycan_count": 7, "hit_score": 0.2, "record_id": "A0A287A1D3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A1E1-1", "uniprot_id": [ { "id": "A0A287A1E1_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A1E1", "type": "external" } ], "mass": 8729.0, "length": 76, "protein_name": "TP53 regulated inhibitor of apoptosis 1", "gene_name": "TRIAP1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TRIAP1", "gene_names_refseq": "", "protein_names_uniprotkb": "TP53 regulated inhibitor of apoptosis 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-6803204)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, 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"glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0015914 phospholipid transport;GO:0120009 intermembrane lipid transfer;GO:0097035 regulation of membrane lipid distribution", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A1E1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A1E6-1", "uniprot_id": [ { "id": "A0A287A1E6_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A1E6", "type": "external" } ], "mass": 75844.0, "length": 681, "protein_name": "RNA helicase", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "RNA helicase; 3.6.4.13", 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Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. 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Can convert acyl and alkyl dihydroxyacetone-phosphate (DHAP) into glycerolipids and ether lipids, respectively, synthesizing ether-linked phospholipids that act as agonists for PPARG. 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Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. Participates in t(6)A37 formation in cytoplasmic and mitochondrial tRNAs. 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ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. 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"filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A2X4-1", "uniprot_id": [ { "id": "A0A287A2X4_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A2X4", "type": "external" } ], "mass": 45277.0, "length": 434, "protein_name": "Transcription factor AP-2 epsilon", "gene_name": "TFAP2E", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TFAP2E", "gene_names_refseq": "", "protein_names_uniprotkb": "Transcription factor AP-2 epsilon", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-8866904); (R-SSC-8866907)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, 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"kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A2X7-1", "uniprot_id": [ { "id": "A0A287A2X7_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A2X7", "type": "external" } ], "mass": 130357.0, "length": 1160, "protein_name": "Hephaestin", "gene_name": "HEPH", "organism": "Pig", "refseq_name": "hephaestin isoform X4", "refseq_ac": [ { "id": "XP_020935432", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935432", "type": "external" } ], "gene_names_uniprotkb": "HEPH", "gene_names_refseq": "HEPH", "protein_names_uniprotkb": "Hephaestin; 1.16.3.1", "protein_names_refseq": "hephaestin isoform X4", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-425410); (R-SSC-917937)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Multifunctional blue, copper-binding (6-7 atoms per molecule) glycoprotein. 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Couples ferroportin which specifically exports ferrous/Fe(2+) iron from cells to transferrin that only binds and shuttles extracellular ferric/Fe(3+) iron throughout the body. 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3.5.4.38", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-72200); (R-SSC-75094)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0004126 cytidine deaminase activity;GO:0008270 zinc ion binding;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000932 P-body", "go_biological_process": "GO:0016554 cytidine to uridine editing;GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0070383 DNA cytosine deamination;GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A3I4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A3K1-1", "uniprot_id": [ { "id": "A0A287A3K1_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A3K1", "type": "external" } ], "mass": 24653.0, "length": 234, "protein_name": "PAXX non-homologous end joining factor", "gene_name": "PAXX", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PAXX", "gene_names_refseq": "", "protein_names_uniprotkb": "PAXX non-homologous end joining factor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0042803 protein homodimerization activity;GO:0070182 DNA polymerase binding", "go_cellular_component": "GO:0070419 nonhomologous end joining complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0035861 site of double-strand break;GO:0043564 Ku70:Ku80 complex", "go_biological_process": "GO:0006303 double-strand break repair via nonhomologous end joining", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A3K1-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A3K6-1", "uniprot_id": [ { "id": "A0A287A3K6_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A3K6", "type": "external" } ], "mass": 53594.0, "length": 479, "protein_name": "Hexosaminidase D", "gene_name": "HEXD", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "HEXD", "gene_names_refseq": "", "protein_names_uniprotkb": "Hexosaminidase D; 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Responsible for the cleavage of the monosaccharides N-acetylglucosamine (GlcNAc) and N-acetylgalactosamine (GalNAc) from cellular substrates. 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0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015929 hexosaminidase activity;GO:0004563 beta-N-acetylhexosaminidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:1903561 extracellular vesicle", "go_biological_process": "GO:0005975 carbohydrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A3K6-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A3M1-1", "uniprot_id": [ { "id": "A0A287A3M1_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A3M1", "type": "external" } ], "mass": 44507.0, "length": 398, "protein_name": "5-hydroxytryptamine receptor 3C", "gene_name": "", "organism": "Pig", 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activity;GO:0005230 extracellular ligand-gated monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse;GO:0045211 postsynaptic membrane;GO:0043005 neuron projection;GO:1902495 transmembrane transporter complex", "go_biological_process": "GO:0042391 regulation of membrane potential;GO:0007268 chemical synaptic transmission;GO:0034220 monoatomic ion transmembrane transport;GO:0140227 serotonin-gated cation-selective signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A3M1-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A3M2-1", "uniprot_id": [ { "id": "A0A287A3M2_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A3M2", "type": "external" } ], "mass": 175409.0, "length": 1722, "protein_name": "Trinucleotide repeat-containing gene 6C protein", "gene_name": "TNRC6C", "organism": 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0, "hit_score": 0.2, "record_id": "A0A287A3M2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A3Q1-1", "uniprot_id": [ { "id": "A0A287A3Q1_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A3Q1", "type": "external" } ], "mass": 34844.0, "length": 304, "protein_name": "Taste receptor type 2", "gene_name": "LOC100154902", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC100154902", "gene_names_refseq": "", "protein_names_uniprotkb": "Taste receptor type 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-418594); (R-SSC-420499); (R-SSC-9717207)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, 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"go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0033038 bitter taste receptor activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A3Q1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A3R0-1", "uniprot_id": [ { "id": "A0A287A3R0_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A3R0", "type": "external" } ], "mass": 34568.0, "length": 296, "protein_name": "L1 transposable element RRM domain-containing protein", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "L1 transposable element RRM domain-containing protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003727 single-stranded RNA binding", "go_cellular_component": "GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0032197 retrotransposition", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A3R0-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A3R9-1", "uniprot_id": [ { "id": "A0A287A3R9_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A3R9", "type": "external" } ], "mass": 34334.0, "length": 307, "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100514275", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC100514275", "gene_names_refseq": "", "protein_names_uniprotkb": "G-protein coupled receptors family 1 profile domain-containing protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100513910)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A3R9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A3S5-1", "uniprot_id": [ { "id": "A0A287A3S5_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A3S5", "type": "external" } ], "mass": 51941.0, "length": 447, "protein_name": "Tektin", "gene_name": "LOC110259951", "organism": "Pig", "refseq_name": "tektin-4", "refseq_ac": [ { "id": "XP_020942531", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942531", "type": "external" } ], "gene_names_uniprotkb": "LOC110259951", "gene_names_refseq": "LOC110259951", "protein_names_uniprotkb": "Tektin", "protein_names_refseq": "tektin-4", "tax_id": 9823, "disease": "", "pathway": " (ssc:110259951)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "32543654;39743588", "class_list": "", "function": "Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0015630 microtubule cytoskeleton;GO:0036126 sperm flagellum;GO:0097228 sperm principal piece;GO:0097225 sperm midpiece;GO:0160111 axonemal A tubule inner sheath", "go_biological_process": "GO:0060294 cilium movement involved in cell motility;GO:0030317 flagellated sperm motility;GO:0060271 cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A287A3S5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A3T1-1", "uniprot_id": [ { "id": "A0A287A3T1_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A3T1", "type": "external" } ], "mass": 29802.0, "length": 272, "protein_name": "Toll-interacting protein", "gene_name": "TOLLIP", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TOLLIP", "gene_names_refseq": "", "protein_names_uniprotkb": "Toll-interacting protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-6798695); (R-SSC-9020702)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity. Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates. In a complex with TOM1, recruits ubiquitin-conjugated proteins onto early endosomes. Binds to phosphatidylinositol 3-phosphate (PtdIns(3)P)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0019900 kinase binding;GO:0031624 ubiquitin conjugating enzyme binding;GO:0043130 ubiquitin binding;GO:0035325 Toll-like receptor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0032991 protein-containing complex", "go_biological_process": "GO:0070498 interleukin-1-mediated signaling pathway;GO:0006954 inflammatory response;GO:0030855 epithelial cell differentiation;GO:0045087 innate immune response;GO:0006914 autophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A3T1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A3T3-1", "uniprot_id": [ { "id": "A0A287A3T3_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A3T3", "type": "external" } ], "mass": 100382.0, "length": 870, "protein_name": "Rab GTPase-binding effector protein 1", "gene_name": "RABEP1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "RABEP1", "gene_names_refseq": "", "protein_names_uniprotkb": "Rab GTPase-binding effector protein 1; Rabaptin-5alpha; Rabaptin-5", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-8854214)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane. Forms a complex with RABGEF1 that stimulates RABGEF1-mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0019904 protein domain specific binding;GO:0042803 protein homodimerization activity;GO:0008083 growth factor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005768 endosome;GO:0005769 early endosome;GO:0005829 cytosol;GO:0055037 recycling endosome", "go_biological_process": "GO:0006897 endocytosis;GO:0015031 protein transport;GO:0006915 apoptotic process;GO:0006893 Golgi to plasma membrane transport;GO:1903441 protein localization to ciliary membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A3T3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A3W6-1", "uniprot_id": [ { "id": "A0A287A3W6_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A3W6", "type": "external" } ], "mass": 105214.0, "length": 942, "protein_name": "DDB1- and CUL4-associated factor 6", "gene_name": "DCAF6", "organism": "Pig", "refseq_name": "DDB1- and CUL4-associated factor 6 isoform X5", "refseq_ac": [ { "id": "XP_020945113", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945113", "type": "external" } ], "gene_names_uniprotkb": "DCAF6", "gene_names_refseq": "DCAF6", "protein_names_uniprotkb": "DDB1- and CUL4-associated factor 6; IQ motif and WD repeat-containing protein 1; Nuclear receptor interaction protein", "protein_names_refseq": "DDB1- and CUL4-associated factor 6 isoform X5", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-8951664)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Ligand-dependent coactivator of nuclear receptors. Enhance transcriptional activity of the nuclear receptors NR3C1 and AR. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0080008 Cul4-RING E3 ubiquitin ligase complex;GO:0005634 nucleus", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A3W6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A3X5-1", "uniprot_id": [ { "id": "A0A287A3X5_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A3X5", "type": "external" } ], "mass": 74225.0, "length": 682, "protein_name": "Solute carrier family 26 member 10", "gene_name": "SLC26A10", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SLC26A10", "gene_names_refseq": "", "protein_names_uniprotkb": "Solute carrier family 26 member 10", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015106 bicarbonate transmembrane transporter activity;GO:0015108 chloride transmembrane transporter activity;GO:0019531 oxalate transmembrane transporter activity;GO:0015116 sulfate transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:1902476 chloride transmembrane transport;GO:1902358 sulfate transmembrane transport;GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A3X5-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A3Z3-1", "uniprot_id": [ { "id": "A0A287A3Z3_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A3Z3", "type": "external" } ], "mass": 34919.0, "length": 313, "protein_name": "Transcription elongation factor", "gene_name": "TCEA2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TCEA2", "gene_names_refseq": "", "protein_names_uniprotkb": "Transcription elongation factor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003711 transcription elongation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006368 transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A3Z3-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A433-1", "uniprot_id": [ { "id": "A0A287A433_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A433", "type": "external" } ], "mass": 34897.0, "length": 311, "protein_name": "Olfactory receptor", "gene_name": "", "organism": "Pig", "refseq_name": "olfactory receptor 4F15-like", "refseq_ac": [ { "id": "XP_020955722", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020955722", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "LOC110261751", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 4F15-like", "tax_id": 9823, "disease": "", "pathway": " (ssc:110261751)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A433-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A437-1", "uniprot_id": [ { "id": "A0A287A437_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A437", "type": "external" } ], "mass": 34647.0, "length": 304, "protein_name": "Serine/threonine-protein kinase 16", "gene_name": "STK16", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "STK16", "gene_names_refseq": "", "protein_names_uniprotkb": "Serine/threonine-protein kinase 16; 2.7.10.2; 2.7.11.1; Myristoylated and palmitoylated serine/threonine-protein kinase; Protein kinase PKL12; TGF-beta-stimulated factor 1; Tyrosine-protein kinase STK16", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, 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} ], "mass": 20226.0, "length": 171, "protein_name": "Cytochrome c oxidase subunit 4", "gene_name": "COX4I2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "COX4I2", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytochrome c oxidase subunit 4", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5628897); (R-SSC-611105); (R-SSC-9707564); (R-SSC-9864848)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8D0LPM5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045277 respiratory chain complex IV", "go_biological_process": "GO:0006123 mitochondrial electron transport, cytochrome c to oxygen", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A440-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A447-1", "uniprot_id": [ { "id": "A0A287A447_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A447", "type": "external" } ], "mass": 49791.0, "length": 437, "protein_name": "Sorting nexin-30", "gene_name": "SNX30", "organism": "Pig", "refseq_name": "sorting nexin-30", "refseq_ac": [ { "id": "XP_003122129", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122129", "type": "external" } ], "gene_names_uniprotkb": "SNX30", "gene_names_refseq": "SNX30", "protein_names_uniprotkb": "Sorting nexin-30", "protein_names_refseq": "sorting nexin-30", "tax_id": 9823, "disease": "", "pathway": " (ssc:100516535)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0005769 early endosome;GO:0031901 early endosome membrane;GO:0000407 phagophore assembly site", "go_biological_process": "GO:0015031 protein transport;GO:0000423 mitophagy;GO:0032456 endocytic recycling;GO:0034727 piecemeal microautophagy of the nucleus;GO:0061709 reticulophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A447-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A463-1", "uniprot_id": [ { "id": "A0A287A463_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A463", "type": "external" } ], "mass": 95808.0, "length": 872, "protein_name": "Holocarboxylase synthetase", "gene_name": "HLCS", "organism": "Pig", "refseq_name": "biotin--protein ligase isoform X1", "refseq_ac": [ { "id": "XP_013838036", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013838036", "type": "external" } ], "gene_names_uniprotkb": "HLCS", "gene_names_refseq": "HLCS", "protein_names_uniprotkb": "Holocarboxylase synthetase", "protein_names_refseq": "biotin--protein ligase isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100515056); (R-SSC-196780)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019899 enzyme binding;GO:0009374 biotin binding;GO:0004077 biotin--[biotin carboxyl-carrier protein] ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016363 nuclear matrix;GO:0000785 chromatin;GO:0005652 nuclear lamina", 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The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000049 tRNA binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005643 nuclear pore;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0071528 tRNA re-export from nucleus;GO:0006886 intracellular protein transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A547-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A561-1", "uniprot_id": [ { "id": "A0A287A561_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A561", "type": "external" } ], "mass": 90241.0, "length": 831, "protein_name": "Kinesin light chain 2", "gene_name": "KLC2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "KLC2", "gene_names_refseq": "", "protein_names_uniprotkb": "Kinesin light chain 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2132295); (R-SSC-5625970); (R-SSC-6811434); (R-SSC-983189)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019894 kinesin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005874 microtubule;GO:0005886 plasma membrane;GO:0005871 kinesin complex", "go_biological_process": "GO:0007018 microtubule-based movement;GO:0032418 lysosome localization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A561-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A5A2-1", "uniprot_id": [ { "id": "A0A287A5A2_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A5A2", "type": "external" } ], "mass": 49305.0, "length": 456, "protein_name": "Transforming growth factor beta-1-induced transcript 1 protein", "gene_name": "TGFB1I1", "organism": "Pig", "refseq_name": "transforming growth factor beta-1-induced transcript 1 protein isoform X1", "refseq_ac": [ { "id": "XP_020942048", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942048", "type": "external" } ], "gene_names_uniprotkb": "TGFB1I1", "gene_names_refseq": "TGFB1I1", "protein_names_uniprotkb": "Transforming growth factor beta-1-induced transcript 1 protein", "protein_names_refseq": "transforming growth factor beta-1-induced transcript 1 protein isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100623028)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0003713 transcription coactivator activity;GO:0050681 nuclear androgen receptor binding;GO:0048495 Roundabout binding;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005925 focal adhesion;GO:0016363 nuclear matrix;GO:0005737 cytoplasm;GO:0005911 cell-cell junction", "go_biological_process": "GO:0030154 cell differentiation;GO:0016055 Wnt signaling pathway;GO:0034446 substrate adhesion-dependent cell spreading;GO:0043542 endothelial cell migration;GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A5A2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A5C2-1", "uniprot_id": [ { "id": "A0A287A5C2_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A5C2", "type": "external" } ], "mass": 70716.0, "length": 682, "protein_name": "PR domain zinc finger protein 8", "gene_name": "PRDM8", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PRDM8", "gene_names_refseq": "", "protein_names_uniprotkb": "PR domain zinc finger protein 8; PR domain-containing protein 8", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity;GO:0046974 histone H3K9 methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016604 nuclear body", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0032259 methylation;GO:0014003 oligodendrocyte development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A5C2-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A5D3-1", "uniprot_id": [ { "id": "A0A287A5D3_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A5D3", "type": "external" } ], "mass": 36306.0, "length": 333, "protein_name": "Neuropeptides B and W receptor 2", "gene_name": "NPBWR2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "NPBWR2", "gene_names_refseq": "", "protein_names_uniprotkb": "Neuropeptides B and W receptor 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-375276); (R-SSC-418594)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0008188 neuropeptide receptor activity;GO:0042923 neuropeptide binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0007218 neuropeptide signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A5D3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A722-1", "uniprot_id": [ { "id": "A0A287A722_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A722", "type": "external" } ], "mass": 33430.0, "length": 308, "protein_name": "3'(2'),5'-bisphosphate nucleotidase 1", "gene_name": "BPNT1", "organism": "Pig", "refseq_name": "3'(2'),5'-bisphosphate nucleotidase 1 isoform X4", "refseq_ac": [ { "id": "XP_003130551", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130551", "type": "external" } ], "gene_names_uniprotkb": "BPNT1", "gene_names_refseq": "BPNT1", "protein_names_uniprotkb": "3'(2'),5'-bisphosphate nucleotidase 1; 3'-phosphoadenosine 5'-phosphate phosphatase; 3.1.3.57; 3.1.3.7; Bisphosphate 3'-nucleotidase 1; Inositol-polyphosphate 1-phosphatase", "protein_names_refseq": "3'(2'),5'-bisphosphate nucleotidase 1 isoform X4", "tax_id": 9823, "disease": "", "pathway": " (ssc:100515917); (R-SSC-156584)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity;GO:0046872 metal ion binding;GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity", "go_cellular_component": "", "go_biological_process": "GO:0046854 phosphatidylinositol phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A722-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A5G9-1", "uniprot_id": [ { "id": "A0A287A5G9_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A5G9", "type": "external" } ], "mass": 65370.0, "length": 595, "protein_name": "APOBEC1 complementation factor", "gene_name": "A1CF", "organism": "Pig", "refseq_name": "APOBEC1 complementation factor isoform X1", "refseq_ac": [ { "id": "XP_005671308", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005671308", "type": "external" } ], "gene_names_uniprotkb": "A1CF", "gene_names_refseq": "A1CF", "protein_names_uniprotkb": "APOBEC1 complementation factor; APOBEC1-stimulating protein", "protein_names_refseq": "APOBEC1 complementation factor isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100155074); (R-SSC-72200); (R-SSC-75094)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8D0INJ9;A0A8D1W8L5", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0003727 single-stranded RNA binding;GO:0140767 enzyme-substrate adaptor activity;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005783 endoplasmic reticulum;GO:0030895 apolipoprotein B mRNA editing enzyme complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0016554 cytidine to uridine editing;GO:0016556 mRNA modification;GO:0050821 protein stabilization;GO:2000623 negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A5G9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A5H8-1", "uniprot_id": [ { "id": "A0A287A5H8_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A5H8", "type": "external" } ], "mass": 38871.0, "length": 337, "protein_name": "Acyltransferase", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Acyltransferase; 2.3.1.-", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004144 diacylglycerol O-acyltransferase activity;GO:0003846 2-acylglycerol O-acyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006651 diacylglycerol biosynthetic process;GO:0019432 triglyceride biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A5H8-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A5I0-1", "uniprot_id": [ { "id": "A0A287A5I0_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A5I0", "type": "external" } ], "mass": 46300.0, "length": 428, "protein_name": "C-terminal-binding protein 1", "gene_name": "CTBP1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CTBP1", "gene_names_refseq": "", "protein_names_uniprotkb": "C-terminal-binding protein 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-3769402); (R-SSC-3899300); (R-SSC-4641265); (R-SSC-9764725)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003714 transcription corepressor activity;GO:0051287 NAD binding;GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0003713 transcription coactivator activity;GO:0019904 protein domain specific binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0017053 transcription repressor complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0051726 regulation of cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A5I0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A5I3-1", "uniprot_id": [ { "id": "A0A287A5I3_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A5I3", "type": "external" } ], "mass": 35189.0, "length": 313, "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100516778", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOC100516778", "gene_names_refseq": "", "protein_names_uniprotkb": "G-protein coupled receptors family 1 profile domain-containing protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100516778)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A5I3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A5I6-1", "uniprot_id": [ { "id": "A0A287A5I6_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A5I6", "type": "external" } ], "mass": 197332.0, "length": 1833, "protein_name": "AT-rich interactive domain-containing protein 2", "gene_name": "ARID2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ARID2", "gene_names_refseq": "", "protein_names_uniprotkb": "AT-rich interactive domain-containing protein 2; 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Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 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"XP_020923722", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020923722", "type": "external" } ], "gene_names_uniprotkb": "KCNJ12", "gene_names_refseq": "KCNJ12", "protein_names_uniprotkb": "Potassium inwardly rectifying channel subfamily J member 12", "protein_names_refseq": "ATP-sensitive inward rectifier potassium channel 12 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1296041); (R-SSC-1296053); (R-SSC-5576886); (R-SSC-997272)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, 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"hit_score": 0.2, "record_id": "A0A287A5K0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A5K8-1", "uniprot_id": [ { "id": "A0A287A5K8_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A5K8", "type": "external" } ], "mass": 8646.0, "length": 74, "protein_name": "Ferritin", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Ferritin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron., [UniProtKB, UniProtKB]; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, 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"reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0005548 phospholipid transporter activity;GO:0005509 calcium ion binding;GO:0030971 receptor tyrosine kinase 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0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A5L5-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A5L7-1", "uniprot_id": [ { "id": "A0A287A5L7_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A5L7", "type": "external" } ], "mass": 89308.0, "length": 790, "protein_name": "Kinesin-like protein", "gene_name": "KIF3C", "organism": "Pig", "refseq_name": "kinesin-like protein KIF3C", "refseq_ac": [ { "id": "XP_020943394", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020943394", "type": "external" } ], "gene_names_uniprotkb": "KIF3C", "gene_names_refseq": "KIF3C", "protein_names_uniprotkb": "Kinesin-like protein", "protein_names_refseq": "kinesin-like protein KIF3C", "tax_id": 9823, "disease": "", "pathway": " (ssc:102158480); (R-SSC-2132295); (R-SSC-5620924); (R-SSC-6811434); (R-SSC-983189)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Microtubule-based molecular motor that transport intracellular cargos, such as vesicles, organelles and protein complexes. Uses ATP hydrolysis to generate force to bind and move along the microtubule. Plays a role in cilia formation. Involved in photoreceptor integrity and opsin trafficking in rod photoreceptors. Transports vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit GRIN2A into neuronal dendrites., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0005871 kinesin complex;GO:0043005 neuron projection;GO:0016939 kinesin II complex", "go_biological_process": "GO:0008088 axo-dendritic transport;GO:0060271 cilium assembly;GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A5L7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A5L9-1", "uniprot_id": [ { "id": "A0A287A5L9_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A5L9", "type": "external" } ], "mass": 66544.0, "length": 605, "protein_name": "Probable ATP-dependent RNA helicase DDX59", "gene_name": "DDX59", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "DDX59", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable ATP-dependent RNA helicase DDX59; 3.6.4.13; DEAD box protein 59; Zinc finger HIT domain-containing protein 5", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016787 hydrolase activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A5L9-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A5Q1-1", "uniprot_id": [ { "id": "A0A287A5Q1_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A5Q1", "type": "external" } ], "mass": 86502.0, "length": 755, "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IKBKB", "gene_names_refseq": "", "protein_names_uniprotkb": "Inhibitor of nuclear factor kappa-B kinase subunit beta; 2.7.11.10; 2.7.11.1; I-kappa-B kinase 2; Nuclear factor NF-kappa-B inhibitor kinase beta; Serine/threonine protein kinase IKBKB", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1169091); (R-SSC-1810476); (R-SSC-202424); (R-SSC-209543); (R-SSC-209560); (R-SSC-2871837); (R-SSC-445989); (R-SSC-5357905); (R-SSC-5357956); (R-SSC-5607764); (R-SSC-5684264); (R-SSC-9020702); (R-SSC-933542); (R-SSC-937039); (R-SSC-937041); (R-SSC-975144); (R-SSC-9758274); (R-SSC-9833482); (R-SSC-9860276); (R-SSC-9860927); (R-SSC-9909505)", "pathway_count": 21, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008384 IkappaB kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0045121 membrane raft;GO:0008385 IkappaB kinase complex", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0033209 tumor necrosis factor-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A5Q1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A5S7-1", "uniprot_id": [ { "id": "A0A287A5S7_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A5S7", "type": "external" } ], "mass": 29718.0, "length": 285, "protein_name": "DDAH family member 2, ADMA-independent", "gene_name": "DDAH2", "organism": "Pig", "refseq_name": "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2", "refseq_ac": [ { "id": "XP_020954117", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954117", "type": "external" } ], "gene_names_uniprotkb": "DDAH2", "gene_names_refseq": "DDAH2", "protein_names_uniprotkb": "DDAH family member 2, ADMA-independent", "protein_names_refseq": "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:110261496)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1VDT4", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0009891 positive regulation of biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A5S7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A5T1-1", "uniprot_id": [ { "id": "A0A287A5T1_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A5T1", "type": "external" } ], "mass": 22531.0, "length": 209, "protein_name": "Putative protein-lysine deacylase ABHD14B", "gene_name": "ABHD14B", "organism": "Pig", "refseq_name": "protein ABHD14B", "refseq_ac": [ { "id": "XP_003358507", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358507", "type": "external" } ], "gene_names_uniprotkb": "ABHD14B", "gene_names_refseq": "ABHD14B", "protein_names_uniprotkb": "Putative protein-lysine deacylase ABHD14B; Alpha/beta hydrolase domain-containing protein 14B", "protein_names_refseq": "protein ABHD14B", "tax_id": 9823, "disease": "", "pathway": " (ssc:100621118); (R-SSC-156584)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Acts as an atypical protein-lysine deacetylase in vitro. Catalyzes the deacetylation of lysine residues using CoA as substrate, generating acetyl-CoA and the free amine of protein-lysine residues. Additional experiments are however required to confirm the protein-lysine deacetylase activity in vivo. Has hydrolase activity towards various surrogate p-nitrophenyl (pNp) substrates, such as pNp-butyrate, pNp-acetate and pNp-octanoate in vitro, with a strong preference for pNp-acetate. May activate transcription., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity;GO:0016746 acyltransferase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005634 nucleus", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A5T1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A5V3-1", "uniprot_id": [ { "id": "A0A287A5V3_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A5V3", "type": "external" } ], "mass": 31400.0, "length": 280, "protein_name": "Borealin", "gene_name": "CDCA8", "organism": "Pig", "refseq_name": 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division;GO:0007080 mitotic metaphase chromosome alignment;GO:0000070 mitotic sister chromatid segregation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A5V3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A5W5-1", "uniprot_id": [ { "id": "A0A287A5W5_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A5W5", "type": "external" } ], "mass": 25037.0, "length": 217, "protein_name": "RAB39A, member RAS onco family", "gene_name": "RAB39A", "organism": "Pig", "refseq_name": "ras-related protein Rab-39A", "refseq_ac": [ { "id": "XP_003129872", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003129872", "type": "external" } ], "gene_names_uniprotkb": "RAB39A", "gene_names_refseq": "RAB39A", "protein_names_uniprotkb": "RAB39A, member RAS onco family", "protein_names_refseq": "ras-related protein Rab-39A", "tax_id": 9823, "disease": "", "pathway": 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"total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0001968 fibronectin binding", "go_cellular_component": "GO:0005604 basement membrane;GO:0005614 interstitial matrix", "go_biological_process": "GO:0030198 extracellular matrix organization;GO:0010811 positive regulation of cell-substrate adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A732-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A748-1", "uniprot_id": [ { "id": "A0A287A748_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A748", "type": "external" } ], "mass": 38332.0, "length": 345, "protein_name": "Tripartite motif containing 44", "gene_name": "TRIM44", "organism": "Pig", "refseq_name": "tripartite motif-containing protein 44 isoform X1", "refseq_ac": [ { "id": "XP_003122913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003122913", "type": "external" } ], "gene_names_uniprotkb": "TRIM44", "gene_names_refseq": "TRIM44", "protein_names_uniprotkb": "Tripartite motif containing 44", "protein_names_refseq": "tripartite motif-containing protein 44 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100524974)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0001961 positive regulation of cytokine-mediated signaling pathway;GO:0045087 innate immune response;GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction;GO:0045893 positive regulation of DNA-templated transcription;GO:0050821 protein stabilization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A748-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A797-1", "uniprot_id": [ { "id": "A0A287A797_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A797", "type": "external" } ], "mass": 231601.0, "length": 2168, "protein_name": "Neuron navigator 1", "gene_name": "NAV1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "NAV1", "gene_names_refseq": "", "protein_names_uniprotkb": "Neuron navigator 1; Pore membrane and/or filament-interacting-like protein 3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "May be involved in neuronal migration., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005874 microtubule;GO:0015630 microtubule cytoskeleton;GO:0043194 axon initial segment", "go_biological_process": "GO:0007399 nervous system development;GO:0001764 neuron migration;GO:0001578 microtubule bundle formation;GO:0022008 neurogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A797-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A799-1", "uniprot_id": [ { "id": "A0A287A799_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A799", "type": "external" } ], "mass": 35784.0, "length": 329, "protein_name": "CAAX prenyl protease 2", "gene_name": "RCE1", "organism": "Pig", "refseq_name": "CAAX prenyl protease 2 isoform X10", "refseq_ac": [ { "id": "XP_013842703", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013842703", "type": "external" } ], "gene_names_uniprotkb": "RCE1", "gene_names_refseq": "RCE1", "protein_names_uniprotkb": "CAAX prenyl protease 2; 3.4.26.1; Farnesylated proteins-converting enzyme 2", "protein_names_refseq": "CAAX prenyl protease 2 isoform X10", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5689880); (R-SSC-9648002)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A480W522", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008238 exopeptidase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0071586 CAAX-box protein processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A799-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A7A5-1", "uniprot_id": [ { "id": "A0A287A7A5_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A7A5", "type": "external" } ], "mass": 37769.0, "length": 344, "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "organism": "Pig", "refseq_name": "polycomb group RING finger protein 2 isoform X2", "refseq_ac": [ { "id": "XP_020922725", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922725", "type": "external" } ], "gene_names_uniprotkb": "PCGF2", "gene_names_refseq": "PCGF2", "protein_names_uniprotkb": "Polycomb group RING finger protein 2; DNA-binding protein Mel-18; RING finger protein 110; Zinc finger protein 144", "protein_names_refseq": "polycomb group RING finger protein 2 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-3108214); (R-SSC-3899300); (R-SSC-4551638); (R-SSC-4570464); (R-SSC-8953750)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Transcriptional repressor. Binds specifically to the DNA sequence 5'-GACTNGACT-3'. Has tumor suppressor activity. May play a role in control of cell proliferation and/or neural cell development. Regulates proliferation of early T progenitor cells by maintaining expression of HES1. Also plays a role in antero-posterior specification of the axial skeleton and negative regulation of the self-renewal activity of hematopoietic stem cells. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A0A8D1YSA6", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:1990841 promoter-specific chromatin binding", "go_cellular_component": "GO:0016604 nuclear body;GO:0035102 PRC1 complex;GO:0001739 sex chromatin", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A7A5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A7B3-1", "uniprot_id": [ { "id": "A0A287A7B3_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A7B3", "type": "external" } ], "mass": 29871.0, "length": 278, "protein_name": "Tumor necrosis factor receptor superfamily member 4", "gene_name": "TNFRSF4", "organism": "Pig", "refseq_name": "tumor necrosis factor receptor superfamily member 4", "refseq_ac": [ { "id": "XP_003127545", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003127545", "type": "external" } ], "gene_names_uniprotkb": "TNFRSF4", "gene_names_refseq": "TNFRSF4", "protein_names_uniprotkb": "Tumor necrosis factor receptor superfamily member 4; OX40L receptor", "protein_names_refseq": "tumor necrosis factor receptor superfamily member 4", "tax_id": 9823, "disease": "", "pathway": " (ssc:100524628); (R-SSC-5669034)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005031 tumor necrosis factor receptor activity", "go_cellular_component": "GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006954 inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A7B3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A7C5-1", "uniprot_id": [ { "id": "A0A287A7C5_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A7C5", "type": "external" } ], "mass": 26253.0, "length": 234, "protein_name": "Mitochondrial assembly of ribosomal large subunit protein 1", "gene_name": "MALSU1", "organism": "Pig", "refseq_name": "mitochondrial assembly of ribosomal large subunit protein 1", "refseq_ac": [ { "id": "XP_020919112", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919112", "type": "external" } ], "gene_names_uniprotkb": "MALSU1", "gene_names_refseq": "MALSU1", "protein_names_uniprotkb": "Mitochondrial assembly of ribosomal large subunit protein 1", "protein_names_refseq": "mitochondrial assembly of ribosomal large subunit protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:106508670); (R-SSC-9937383)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Required for normal mitochondrial ribosome function and mitochondrial translation. May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits. Interacts with mitochondrial ribosomal protein uL14m (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome. May function as a ribosomal silencing factor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043023 ribosomal large subunit binding;GO:0140978 mitochondrial large ribosomal subunit binding", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0017148 negative regulation of translation;GO:1902775 mitochondrial large ribosomal subunit assembly;GO:0070130 negative regulation of mitochondrial translation;GO:0090071 negative regulation of ribosome biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A7C5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A7C9-1", "uniprot_id": [ { "id": "A0A287A7C9_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A7C9", "type": "external" } ], "mass": 32752.0, "length": 292, "protein_name": "E3 ubiquitin-protein ligase RNF144A", "gene_name": "RNF144A", "organism": "Pig", "refseq_name": "E3 ubiquitin-protein ligase RNF144A isoform X2", "refseq_ac": [ { "id": "XP_005662823", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005662823", "type": "external" } ], "gene_names_uniprotkb": "RNF144A", "gene_names_refseq": "RNF144A", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF144A; 2.3.2.31; RING finger protein 144A; UbcM4-interacting protein 4; Ubiquitin-conjugating enzyme 7-interacting protein 4", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF144A isoform X2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100514456); (R-SSC-8866654)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the ubiquitination and degradation of the DNA damage kinase PRKDC during DNA damage. Positively regulates DNA virus or exogenous cytosolic DNA-triggered innate immune response by mediating STING1 ubiquitination and increasing its 'Lys-6'-linked ubiquitination and translocation from the endoplasmic reticulum to the Golgi leading to downstream signaling pathways. Plays a positive role in EGF-dependent cell proliferation by prolonging EGF/EGFR signaling during EGF stimulation through EGFR ubiquitination. Increases ERK activity independently of EGFR signaling by promoting polyubiquitination and subsequent degradation of VRK3 in the cytosol., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1UGA1", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0031624 ubiquitin conjugating enzyme binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0031090 organelle membrane;GO:0000151 ubiquitin ligase complex;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0002221 pattern recognition receptor signaling pathway;GO:0085020 protein K6-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A7C9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A7E2-1", "uniprot_id": [ { "id": "A0A287A7E2_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A7E2", "type": "external" } ], "mass": 35878.0, "length": 320, "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "organism": "Pig", "refseq_name": "olfactory receptor 2W1-like", "refseq_ac": [ { "id": "XP_020937670", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937670", "type": "external" } ], "gene_names_uniprotkb": "LOC110258743", "gene_names_refseq": "LOC110258743", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 2W1-like", "tax_id": 9823, "disease": "", "pathway": " (ssc:110258743)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A7E2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A7F6-1", "uniprot_id": [ { "id": "A0A287A7F6_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A7F6", "type": "external" } ], "mass": 29883.0, "length": 267, "protein_name": "Prohibitin", "gene_name": "PHB2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PHB2", "gene_names_refseq": "", "protein_names_uniprotkb": "Prohibitin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100627467); (R-SSC-8949664); (R-SSC-9840373)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "In the mitochondria, together with PHB, forms large ring complexes (prohibitin complexes) in the inner mitochondrial membrane (IMM) and functions as a chaperone protein that stabilizes mitochondrial respiratory enzymes and maintains mitochondrial integrity in the IMM, which is required for mitochondrial morphogenesis, neuronal survival, and normal lifespan. The prohibitin complex, with DNAJC19, regulates cardiolipin remodeling and the protein turnover of OMA1 in a cardiolipin-binding manner. Also regulates cytochrome-c oxidase assembly (COX) and mitochondrial respiration. Binding to sphingoid 1-phosphate (SPP) modulates its regulator activity. Has a key role of mitophagy receptor involved in targeting mitochondria for autophagic degradation. Involved in mitochondrial-mediated antiviral innate immunity, activates RIG-I-mediated signal transduction and production of IFNB1 and pro-inflammatory cytokine IL6., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; In the nucleus, serves as transcriptional co-regulator. Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; In the plasma membrane, is involved in IGFBP6-induced cell migration. Cooperates with CD86 to mediate CD86-signaling in B lymphocytes that regulates the level of IgG1 produced through the activation of distal signaling intermediates. Upon CD40 engagement, required to activate NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors and sex steroid hormones in the nucleus., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0033218 amide binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0046625 sphingolipid binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0016477 cell migration;GO:0043066 negative regulation of apoptotic process;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A7F6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A4E7-1", "uniprot_id": [ { "id": "A0A287A4E7_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A4E7", "type": "external" } ], "mass": 41382.0, "length": 358, "protein_name": "cAMP-dependent protein kinase catalytic subunit beta", "gene_name": "PRKACB", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PRKACB", "gene_names_refseq": "", "protein_names_uniprotkb": "cAMP-dependent protein kinase catalytic subunit beta; 2.7.11.11", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates GPKOW which regulates its ability to bind RNA. Acts as a negative regulator of mTORC1 by mediating phosphorylation of RPTOR., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0004691 cAMP-dependent protein kinase activity;GO:0000287 magnesium ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005813 centrosome;GO:0005829 cytosol", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:1904262 negative regulation of TORC1 signaling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A4E7-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q4JHS0-1", "uniprot_id": [ { "id": "BID_PIG", "url": "https://www.uniprot.org/uniprot/Q4JHS0", "type": "external" } ], "mass": 21569.0, "length": 192, "protein_name": "BH3-interacting domain death agonist", "gene_name": "BID", "organism": "Pig", "refseq_name": "BH3-interacting domain death agonist", "refseq_ac": [ { "id": "NP_001025706", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025706", "type": "external" } ], "gene_names_uniprotkb": "BID", "gene_names_refseq": "BID; p22 BID", "protein_names_uniprotkb": "BH3-interacting domain death agonist; BID; p11 BID; p13 BID; p15 BID; p22 BID", "protein_names_refseq": "BH3-interacting domain death agonist; BID", "tax_id": 9823, "disease": "", "pathway": " (ssc:594852); (R-SSC-111447); (R-SSC-111452); (R-SSC-111453); (R-SSC-114294); (R-SSC-75108)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "21441714;32543654", "class_list": "", "function": "Bid and Bax are signal transduction factors in granulosa cells and play proapoptotic roles., [RefSeq, PubMed]; Induces caspase activation and apoptosis. Translocates to mitochondria following cleavage and disrupts the outer mitochondrial membrane leading to the release of cytochrome c., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Induces caspases and apoptosis. Counters the protective effect of BCL2., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q56VC1", "ec_number_list": [], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005829 cytosol", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:2001238 positive regulation of extrinsic apoptotic signaling pathway;GO:0001836 release of cytochrome c from mitochondria;GO:0090200 positive regulation of release of cytochrome c from mitochondria;GO:2001244 positive regulation of intrinsic apoptotic signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q4JHS0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q2QDF0-1", "uniprot_id": [ { "id": "DNSL1_PIG", "url": "https://www.uniprot.org/uniprot/Q2QDF0", "type": "external" } ], "mass": 34986.0, "length": 315, "protein_name": "Deoxyribonuclease-1-like 1", "gene_name": "DNASE1L1", "organism": "Pig", "refseq_name": "deoxyribonuclease-1-like 1 precursor", "refseq_ac": [ { "id": "NP_001033721", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033721", "type": "external" } ], "gene_names_uniprotkb": "DNASE1L1", "gene_names_refseq": "DNASE1L1", "protein_names_uniprotkb": "Deoxyribonuclease-1-like 1; 3.1.21.-; DNase I-like 1; DNase X; Deoxyribonuclease I-like 1", "protein_names_refseq": "DNase I-like 1; DNase X; deoxyribonuclease I-like 1; deoxyribonuclease-1-like 1 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:654408); (R-SSC-6798695)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "16107205;32543654", "class_list": "", "function": "Interestingly, the translation of porcine and bovine DNase X proteins occurs in the absence of an in-frame AUG initiation codon GeneRIF: replacement of proposed downstream alternate translation initiation triplet CTG with TTT, which has no potential for translation initiation, resulted in no protein synthesis, [RefSeq, PubMed]; This gene encodes a member of the deoxyribonuclease family and the protein shows high sequence similarity to lysosomal DNase I. In contrast to the human and mouse orthologs, porcine and bovine mRNAs for this gene use a conserved CUG triplet for translation initiation. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0004530 deoxyribonuclease I activity;GO:0016787 hydrolase activity;GO:0004519 endonuclease activity;GO:0004536 DNA nuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006308 DNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q2QDF0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29102-1", "uniprot_id": [ { "id": "OPALI_PIG", "url": "https://www.uniprot.org/uniprot/Q29102", "type": "external" } ], "mass": 15771.0, "length": 142, "protein_name": "Opalin", "gene_name": "OPALIN", "organism": "Pig", "refseq_name": "opalin", "refseq_ac": [ { "id": "NP_999375", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999375", "type": "external" } ], "gene_names_uniprotkb": "OPALIN; SP83.5; TMEM10", "gene_names_refseq": "OPALIN; SP83.5; TMEM10", "protein_names_uniprotkb": "Opalin; Oligodendrocytic myelin paranodal and inner loop protein; Transmembrane protein 10; Transmembrane protein sp83.5", "protein_names_refseq": "opalin; transmembrane protein 10; transmembrane protein sp83.5", "tax_id": 9823, "disease": "", "pathway": " (ssc:397416)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "32543654;9746342", "class_list": "", "function": "Central nervous system-specific myelin protein that increase myelin genes expression during oligodendrocyte differentiation. Promotes oligodendrocyte terminal differentiation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005794 Golgi apparatus;GO:0044291 cell-cell contact zone", "go_biological_process": "GO:0048713 regulation of oligodendrocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q29102-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9N2D1-1", "uniprot_id": [ { "id": "TRYT_PIG", "url": "https://www.uniprot.org/uniprot/Q9N2D1", "type": "external" } ], "mass": 30439.0, "length": 275, "protein_name": "Tryptase", "gene_name": "MCT7", "organism": "Pig", "refseq_name": "tryptase precursor", "refseq_ac": [ { "id": "NP_999356", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999356", "type": "external" } ], "gene_names_uniprotkb": "MCT7", "gene_names_refseq": "MCT7; 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Inhibits APP transport to the cell surface and further shedding., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Chromosome mapping of 3 proteins (CRSP9, ETF1 and TMEM59) in swine, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, 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"A0A287A7F8_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A7F8", "type": "external" } ], "mass": 49980.0, "length": 442, "protein_name": "GA-binding protein alpha chain", "gene_name": "GABPA", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "GABPA", "gene_names_refseq": "", "protein_names_uniprotkb": "GA-binding protein alpha chain", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2151201)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, 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"record_id": "A0A287A7I7-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A7J9-1", "uniprot_id": [ { "id": "A0A287A7J9_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A7J9", "type": "external" } ], "mass": 34554.0, "length": 309, "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "organism": "Pig", "refseq_name": "putative olfactory receptor 5AK3", "refseq_ac": [ { "id": "XP_020937676", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020937676", "type": "external" } ], "gene_names_uniprotkb": "LOC110258750", "gene_names_refseq": "LOC110258750", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "putative olfactory receptor 5AK3", "tax_id": 9823, "disease": "", "pathway": " (ssc:110258750)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A7J9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8SPK1-1", "uniprot_id": [ { "id": "CP4AO_PIG", "url": "https://www.uniprot.org/uniprot/Q8SPK1", "type": "external" } ], "mass": 57199.0, "length": 504, "protein_name": "Cytochrome P450 4A24", "gene_name": "CYP4A24", "organism": "Pig", "refseq_name": "cytochrome P450 4A25", "refseq_ac": [ { "id": "NP_999589", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999589", "type": "external" } ], "gene_names_uniprotkb": "CYP4A24", "gene_names_refseq": "CYP4A24; CYP4A25; CYPIVA24", "protein_names_uniprotkb": "Cytochrome P450 4A24; 1.14.14.80; CYPIVA24; Fatty acid omega-hydroxylase; Long-chain fatty acid omega-monooxygenase", "protein_names_refseq": "CYPIVA25; cytochrome P450 4A24; cytochrome P450 4A25; fatty acid omega-hydroxylase; long-chain fatty acid omega-monooxygenase", "tax_id": 9823, "disease": "", "pathway": " (ssc:403326); (R-SSC-211935); (R-SSC-211958); (R-SSC-211979); (R-SSC-2142691); (R-SSC-2142816)", "pathway_count": 6, "publication_count": 3, "publication_id_list": "11931657;14641109;32543654", "class_list": "", "function": "Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate and palmitate. Has no activity toward taurochenodeoxycholic acid., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q70BW1;Q70BZ6", "ec_number_list": [], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0102033 long-chain fatty acid omega-hydroxylase activity;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8SPK1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95281-1", "uniprot_id": [ { "id": "RL29_PIG", "url": "https://www.uniprot.org/uniprot/Q95281", "type": "external" } ], "mass": 17498.0, "length": 160, "protein_name": "Large ribosomal subunit protein eL29", "gene_name": "RPL29", "organism": "Pig", "refseq_name": "large ribosomal subunit protein eL29", "refseq_ac": [ { "id": "NP_999115", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999115", "type": "external" } ], "gene_names_uniprotkb": "RPL29", "gene_names_refseq": "RPL29/HIP; RPL29", "protein_names_uniprotkb": "Large ribosomal subunit protein eL29; 60S ribosomal protein L29", "protein_names_refseq": "60S ribosomal protein L29; cell surface heparin binding protein HIP; large ribosomal subunit protein eL29", "tax_id": 9823, "disease": "", "pathway": " (ssc:396993); (R-SSC-156827); (R-SSC-1799339); (R-SSC-6791226); (R-SSC-72689); (R-SSC-72706); (R-SSC-975956); (R-SSC-975957); (R-SSC-9954709); (R-SSC-9954714); (R-SSC-9954716)", "pathway_count": 11, "publication_count": 3, "publication_id_list": "19747524;32543654;8672129", "class_list": "", "function": "A molecular-level explanation for the pH-dependent binding of beta-amyloid peptides by heparin and heparan sulfate proteoglycan and may have implications for amyloid formation., [RefSeq, PubMed]; Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9XS36", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane;GO:0022625 cytosolic large ribosomal subunit;GO:0015934 large ribosomal subunit;GO:0005737 cytoplasm;GO:0005840 ribosome", "go_biological_process": "GO:0002181 cytoplasmic translation;GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q95281-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MJD6-1", "uniprot_id": [ { "id": "HOP_PIG", "url": "https://www.uniprot.org/uniprot/Q8MJD6", "type": "external" } ], "mass": 8320.0, "length": 73, "protein_name": "Homeodomain-only protein", "gene_name": "HOPX", "organism": "Pig", "refseq_name": "homeodomain-only protein", "refseq_ac": [ { "id": "NP_998957", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998957", "type": "external" } ], "gene_names_uniprotkb": "HOPX; HOD; HOP; OB1", "gene_names_refseq": "HOPX; OB1", "protein_names_uniprotkb": "Homeodomain-only protein; Odd homeobox protein 1", "protein_names_refseq": "homeodomain-only protein; odd homeobox 1 protein; odd homeobox protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:396692)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "14516659;32543654", "class_list": "", "function": "Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0001829 trophectodermal cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8MJD6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q52I78-1", "uniprot_id": [ { "id": "NAMPT_PIG", "url": "https://www.uniprot.org/uniprot/Q52I78", "type": "external" } ], "mass": 55374.0, "length": 491, "protein_name": "Nicotinamide phosphoribosyltransferase", "gene_name": "NAMPT", "organism": "Pig", "refseq_name": "nicotinamide phosphoribosyltransferase", "refseq_ac": [ { "id": "NP_001026963", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026963", "type": "external" } ], "gene_names_uniprotkb": "NAMPT; PBEF1", "gene_names_refseq": "NAMPT; PBEF1", "protein_names_uniprotkb": "Nicotinamide phosphoribosyltransferase; 2.4.2.12; NAmPRTase; Nampt; PBEF; Pre-B-cell colony-enhancing factor 1 homolog; Visfatin", "protein_names_refseq": "NAmPRTase; PBEF; nicotinamide phosphoribosyltransferase; pre-B-cell colony enhancing factor 1; pre-B-cell colony-enhancing factor 1 homolog; visfatin", "tax_id": 9823, "disease": "", "pathway": " (ssc:595123); (R-SSC-196807)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "16857338;18343625;20477789;32543654;37562189", "class_list": "", "function": "Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression., [UniProtKB, UniProtKB, UniProtKB]; Cloning and characterization of porcine visfatin and its three alternate splicing variants is reported; sequence analysis indicated that variant 1 is the predominant form among species., [RefSeq, PubMed]; Expression of visfatin in the ovarian follicles of prepubertal and mature gilts and in vitro effect of gonadotropins, insulin, steroids, and prostaglandins on visfatin levels., [RefSeq, PubMed]; In a wild boar x Meishan F2 family nicotinamide phosphoribosyltransferase nicotinamide phosphoribosyltransferase SNP 669T>C was associated with muscling, fat deposition, growth and fattening, meat quality and other traits., [RefSeq, PubMed]; The porcine visfatin gene cannot be considered as a marker of fat accumulation since the highest visfatin expression levels were associated with the leaner animals., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3I6K8", "ec_number_list": [], "go_molecular_function": "GO:0047280 nicotinamide phosphoribosyltransferase activity;GO:0042802 identical protein binding;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005759 mitochondrial matrix;GO:0005829 cytosol", "go_biological_process": "GO:0009435 NAD+ biosynthetic process;GO:0032922 circadian regulation of gene expression;GO:0048511 rhythmic process;GO:0006741 NADP+ biosynthetic process;GO:0006954 inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q52I78-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29293-1", "uniprot_id": [ { "id": "RL3_PIG", "url": "https://www.uniprot.org/uniprot/Q29293", "type": "external" } ], "mass": 46123.0, "length": 403, "protein_name": "Large ribosomal subunit protein uL3", "gene_name": "RPL3", "organism": "Pig", "refseq_name": "large ribosomal subunit protein uL3", "refseq_ac": [ { "id": "NP_001230992", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230992", "type": "external" } ], "gene_names_uniprotkb": "RPL3", "gene_names_refseq": "RPL3", "protein_names_uniprotkb": "Large ribosomal subunit protein uL3; 60S ribosomal protein L3", "protein_names_refseq": "60S ribosomal protein L3; large ribosomal subunit protein uL3", "tax_id": 9823, "disease": "", "pathway": " (ssc:396768); (R-SSC-156827); (R-SSC-1799339); (R-SSC-6791226); (R-SSC-72689); (R-SSC-72706); (R-SSC-975956); (R-SSC-975957); (R-SSC-9954709); (R-SSC-9954714); (R-SSC-9954716)", "pathway_count": 11, "publication_count": 2, "publication_id_list": "32543654;8672129", "class_list": "", "function": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1VV59", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005730 nucleolus;GO:0022625 cytosolic large ribosomal subunit;GO:0005737 cytoplasm;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006412 translation;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q29293-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q07717-1", "uniprot_id": [ { "id": "B2MG_PIG", "url": "https://www.uniprot.org/uniprot/Q07717", "type": "external" } ], "mass": 13362.0, "length": 118, "protein_name": "Beta-2-microglobulin", "gene_name": "B2M", "organism": "Pig", "refseq_name": "beta-2-microglobulin precursor", "refseq_ac": [ { "id": "NP_999143", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999143", "type": "external" } ], "gene_names_uniprotkb": "B2M", "gene_names_refseq": "B2M", "protein_names_uniprotkb": "Beta-2-microglobulin; Lactollin", "protein_names_refseq": "beta-2-microglobulin precursor; lactollin", "tax_id": 9823, "disease": "", "pathway": " (ssc:110255236); (ssc:397033); (R-SSC-1236974); (R-SSC-1236977); (R-SSC-198933); (R-SSC-2424491); (R-SSC-6798695); (R-SSC-983170)", "pathway_count": 8, "publication_count": 4, "publication_id_list": "20222444;32543654;8406623;8672129", "class_list": "", "function": "B2M contains alpha-helix, beta-sheet, turn, and random coil., [RefSeq, PubMed]; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8WN08", "ec_number_list": [], "go_molecular_function": "GO:0023026 MHC class II protein complex binding;GO:0042605 peptide antigen binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0042613 MHC class II protein complex;GO:0042612 MHC class I protein complex", "go_biological_process": "GO:0006955 immune response;GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0002474 antigen processing and presentation of peptide antigen via MHC class I;GO:0002503 peptide antigen assembly with MHC class II protein complex;GO:0050870 positive regulation of T cell activation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q07717-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29593-1", "uniprot_id": [ { "id": "TALDO_PIG", "url": "https://www.uniprot.org/uniprot/Q29593", "type": "external" } ], "mass": 37418.0, "length": 337, "protein_name": "Transaldolase", "gene_name": "TALDO1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TALDO1", "gene_names_refseq": "", "protein_names_uniprotkb": "Transaldolase; 2.2.1.2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-163754); (R-SSC-71336)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "32543654;8672129", "class_list": "", "function": "Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1RYY6", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0004801 transaldolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0009052 pentose-phosphate shunt, non-oxidative branch;GO:0005975 carbohydrate metabolic process;GO:0006098 pentose-phosphate shunt", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q29593-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9TSW0-1", "uniprot_id": [ { "id": "TRI15_PIG", "url": "https://www.uniprot.org/uniprot/Q9TSW0", "type": "external" } ], "mass": 51578.0, "length": 461, "protein_name": "E3 ubiquitin-protein ligase TRIM15", "gene_name": "TRIM15", "organism": "Pig", "refseq_name": "E3 ubiquitin-protein ligase TRIM15", "refseq_ac": [ { "id": "NP_001116680", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116680", "type": "external" } ], "gene_names_uniprotkb": "TRIM15; ZNFB7", "gene_names_refseq": "TRIM15; znfb7", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TRIM15; 2.3.2.27; Zinc finger protein B7", "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM15; Tripartite motif-containing protein 15; zinc finger protein B7", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144461)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11685460;32543654", "class_list": "", "function": "E3 ubiquitin ligase that plays a role in several processes including innate antiviral immnity, cell migration and chemotaxis. Acts as a 'Lys-63'-specific ubiquitin ligase for MAPK1/ERK2 and MAPK3/ERK1, promoting their activation by facilitating their interaction with MAP2K1 and MAP2K2. Also plays a role in cell migration and chemotaxis by acting as a stable focal adhesion component upon recruitment by multi-adapter protein paxillin/PXN. Functions in the RIGI-mediated interferon induction pathway upstream or at the level of MAVS. Inhibits NF-kappa-B activation by turnover of 'Lys-63'-linked ubiquitination of MAP3K7/TAK1. Mechanistically, prevents TRIM8 cytoplasmic translocation and thus inhibits TRIM8-mediated 'Lys-63'-linked polyubiquitination of MAP3K7/TAK1 in the cytoplasm. Also has an important regulatory effect on the activation of hepatic stellate cells (HSCs)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0140313 molecular sequestering activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005925 focal adhesion", "go_biological_process": "GO:0044790 suppression of viral release by host;GO:0045087 innate immune response;GO:1901223 negative regulation of non-canonical NF-kappaB signal transduction;GO:1900246 positive regulation of RIG-I signaling pathway;GO:0032481 positive regulation of type I interferon production", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9TSW0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q75ZZ6-1", "uniprot_id": [ { "id": "TNNT1_PIG", "url": "https://www.uniprot.org/uniprot/Q75ZZ6", "type": "external" } ], "mass": 31243.0, "length": 262, "protein_name": "Troponin T, slow skeletal muscle", "gene_name": "TNNT1", "organism": "Pig", "refseq_name": "troponin T, slow skeletal muscle", "refseq_ac": [ { "id": "NP_998913", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998913", "type": "external" } ], "gene_names_uniprotkb": "TNNT1", "gene_names_refseq": "TNNT1", "protein_names_uniprotkb": "Troponin T, slow skeletal muscle; Slow skeletal muscle troponin T; TnTs; sTnT", "protein_names_refseq": "sTnT; slow skeletal muscle troponin T; tnTs; troponin T, slow skeletal muscle", "tax_id": 9823, "disease": "", "pathway": " (ssc:396579); (R-SSC-390522)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "16556993;32543654", "class_list": "", "function": "Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q75ZZ5", "ec_number_list": [], "go_molecular_function": "GO:0031014 troponin T binding;GO:0005523 tropomyosin binding", "go_cellular_component": "GO:0005861 troponin complex", "go_biological_process": "GO:0045214 sarcomere organization;GO:0006937 regulation of muscle contraction;GO:0031444 slow-twitch skeletal muscle fiber contraction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q75ZZ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q767L0-1", "uniprot_id": [ { "id": "ABCF1_PIG", "url": "https://www.uniprot.org/uniprot/Q767L0", "type": "external" } ], "mass": 91637.0, "length": 807, "protein_name": "ATP-binding cassette sub-family F member 1", "gene_name": "ABCF1", "organism": "Pig", "refseq_name": "ATP-binding cassette sub-family F member 1", "refseq_ac": [ { "id": "NP_001116541", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116541", "type": "external" } ], "gene_names_uniprotkb": "ABCF1", "gene_names_refseq": "ABCF1", "protein_names_uniprotkb": "ATP-binding cassette sub-family F member 1", "protein_names_refseq": "ATP-binding cassette sub-family F member 1; ATP-binding cassette, sub-family F (GCN20), member 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144452)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "14673549;32543654", "class_list": "", "function": "Required for efficient Cap- and IRES-mediated mRNA translation initiation. Not involved in the ribosome biogenesis (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0008494 translation activator activity;GO:0043022 ribosome binding", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006413 translational initiation;GO:0045727 positive regulation of translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q767L0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q06AU4-1", "uniprot_id": [ { "id": "RAB34_PIG", "url": "https://www.uniprot.org/uniprot/Q06AU4", "type": "external" } ], "mass": 29115.0, "length": 259, "protein_name": "Ras-related protein Rab-34", "gene_name": "RAB34", "organism": "Pig", "refseq_name": "ras-related protein Rab-34", "refseq_ac": [ { "id": "NP_001116650", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116650", "type": "external" } ], "gene_names_uniprotkb": "RAB34", "gene_names_refseq": "RAB34", "protein_names_uniprotkb": "Ras-related protein Rab-34; 3.6.5.2", "protein_names_refseq": "RAB34, member of RAS oncogene family; ras-related protein Rab-34", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144491)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (By similarity). Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). RAB34 transports protein involved in the redistribution of lysosomes to the peri-Golgi region (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis (By similarity). Plays a role in the fusion of phagosomes with lysosomes (By similarity). Required for the early steps of intracellular ciliogenesis, the cilium assembly pathway initiated by trafficking and docking of ciliary vesicles to the centrioles in the cytoplasm, followed by axoneme formation in the cytoplasm. After axoneme elongation, the centrioles migrate close to the cell surface so that ciliary vesicles can fuse with the plasma membrane to expose cilia to the extracellular space. It seems dispensable for ciliogenesis via the extracellular pathway where cilium assembly begins after migration and docking of the centriole to the plasma membrane. Also acts as a positive regulator of hedgehog signaling and regulates ciliary function (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0003925 G protein activity;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005813 centrosome;GO:0005929 cilium;GO:0030670 phagocytic vesicle membrane;GO:0045335 phagocytic vesicle;GO:0005814 centriole", "go_biological_process": "GO:0045880 positive regulation of smoothened signaling pathway;GO:0090382 phagosome maturation;GO:0060271 cilium assembly;GO:0043001 Golgi to plasma membrane protein transport;GO:0090385 phagosome-lysosome fusion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q06AU4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q56P27-1", "uniprot_id": [ { "id": "NIP7_PIG", "url": "https://www.uniprot.org/uniprot/Q56P27", "type": "external" } ], "mass": 20491.0, "length": 180, "protein_name": "60S ribosome subunit biogenesis protein NIP7 homolog", "gene_name": "NIP7", "organism": "Pig", "refseq_name": "60S ribosome subunit biogenesis protein NIP7 homolog", "refseq_ac": [ { "id": "NP_001041536", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001041536", "type": "external" } ], "gene_names_uniprotkb": "NIP7", "gene_names_refseq": "NIP7", "protein_names_uniprotkb": "60S ribosome subunit biogenesis protein NIP7 homolog; Nucleolar pre-rRNA processing protein NIP7", "protein_names_refseq": "60S ribosome subunit biogenesis protein NIP7 homolog; NIP7, nucleolar pre-rRNA processing protein; PUA protein; nuclear import 7 homolog", "tax_id": 9823, "disease": "", "pathway": " (ssc:595107)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "17187224;32543654", "class_list": "", "function": "Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly., [UniProtKB]; Study is the first to establish the primary foundation for further research on the swine NIP7 gene (AY864609)., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q52QS1", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor", "go_biological_process": "GO:0042273 ribosomal large subunit biogenesis;GO:0042255 ribosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q56P27-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1A730-1", "uniprot_id": [ { "id": "FBX32_PIG", "url": "https://www.uniprot.org/uniprot/Q1A730", "type": "external" } ], "mass": 41666.0, "length": 355, "protein_name": "F-box only protein 32", "gene_name": "FBXO32", "organism": "Pig", "refseq_name": "F-box only protein 32", "refseq_ac": [ { "id": "NP_001038053", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038053", "type": "external" } ], "gene_names_uniprotkb": "FBXO32", "gene_names_refseq": "FBXO32; MAFbx", "protein_names_uniprotkb": "F-box only protein 32", "protein_names_refseq": "F-box only protein 32", "tax_id": 9823, "disease": "", "pathway": " (ssc:733657); (R-SSC-8951664); (R-SSC-983168)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "16869957;28064564;29978277;32543654", "class_list": "", "function": "Porcine congenital splayleg (PCS) is a condition characterized by extensive fibre atrophy and raised fibre density. The combined differential expression of MAFbx and P311 is of potential in the diagnosis of subclinical PCS. Publication Status: Online-Only, [RefSeq, PubMed]; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1. Negatively regulates macrophage efferocytosis by promoting the ubiquitination of the transcription factor KLF4, suppressing the receptor tyrosine kinase MERTK transcription (By similarity). Regulates LPS-induced apoptosis and mitochondrial dysfunction through ANXA1 ubiquitination and degradation (By similarity). Mediates cyclin D1 protein stabilization via 'Lys-27'-linked ubiquitination (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; This study shows that aspartate suppresses lipopolysaccharide-induced MAFbx expression in skeletal muscle via activation of Akt signaling, and inhibition of AMPKa and FOXO1 signaling, [RefSeq, PubMed]; We speculated that the overexpression of FBXO32 is responsible for congenital splay leg syndrome and it plays an important role in the PI3K-Akt pathway, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0019005 SCF ubiquitin ligase complex", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0014894 response to denervation involved in regulation of muscle adaptation;GO:0062026 negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q1A730-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6Q7J5-1", "uniprot_id": [ { "id": "MED27_PIG", "url": "https://www.uniprot.org/uniprot/Q6Q7J5", "type": "external" } ], "mass": 35375.0, "length": 311, "protein_name": "Mediator of RNA polymerase II transcription subunit 27", "gene_name": "MED27", "organism": "Pig", "refseq_name": "mediator of RNA polymerase II transcription subunit 27", "refseq_ac": [ { "id": "NP_001001644", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001644", "type": "external" } ], "gene_names_uniprotkb": "MED27; CRSP8", "gene_names_refseq": "CRSP8; MED27", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 27; CRSP complex subunit 8; Cofactor required for Sp1 transcriptional activation subunit 8; Mediator complex subunit 27", "protein_names_refseq": "CRSP complex subunit 8; cofactor required for Sp1 transcriptional activation subunit 8; cofactor required for Sp1 transcriptional activation, subunit 8, 34kDa; mediator of RNA polymerase II transcription subunit 27", "tax_id": 9823, "disease": "", "pathway": " (ssc:414430); (R-SSC-9841922)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005667 transcription regulator complex;GO:0016592 mediator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6Q7J5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95339-1", "uniprot_id": [ { "id": "ATPK_PIG", "url": "https://www.uniprot.org/uniprot/Q95339", "type": "external" } ], "mass": 10311.0, "length": 88, "protein_name": "ATP synthase F(0) complex subunit f, mitochondrial", "gene_name": "ATP5MF", "organism": "Pig", "refseq_name": "ATP synthase F(0) complex subunit f, mitochondrial", "refseq_ac": [ { "id": "NP_001090933", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001090933", "type": "external" } ], "gene_names_uniprotkb": "ATP5MF; ATP5J2", "gene_names_refseq": "ATP5J2; ATP5MF", "protein_names_uniprotkb": "ATP synthase F(0) complex subunit f, mitochondrial; ATP synthase membrane subunit f", "protein_names_refseq": "ATP synthase F(0) complex subunit f, mitochondrial; ATP synthase subunit f, mitochondrial; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2; ATP synthase, H+ transporting, mitochondrial Fo complex subunit F2; mitochondrial Atp5j2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100037979)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Subunit f, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1XQR8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0006754 ATP biosynthetic process;GO:1902600 proton transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q95339-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q19QT9-1", "uniprot_id": [ { "id": "TYW3_PIG", "url": "https://www.uniprot.org/uniprot/Q19QT9", "type": "external" } ], "mass": 29480.0, "length": 259, "protein_name": "tRNA wybutosine-synthesizing protein 3 homolog", "gene_name": "TYW3", "organism": "Pig", "refseq_name": "tRNA wybutosine-synthesizing protein 3 homolog", "refseq_ac": [ { "id": "NP_001038048", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038048", "type": "external" } ], "gene_names_uniprotkb": "TYW3", "gene_names_refseq": "TYW3", "protein_names_uniprotkb": "tRNA wybutosine-synthesizing protein 3 homolog; 2.1.1.282; tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase; tRNA-yW-synthesizing protein 3", "protein_names_refseq": "tRNA wybutosine-synthesizing protein 3 homolog; tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))- methyltransferase; tRNA-yW protein 3 synthesizing homolog; tRNA-yW-synthesizing protein 3", "tax_id": 9823, "disease": "", "pathway": " (ssc:733652)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16978188;32543654", "class_list": "", "function": "Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA., [UniProtKB, UniProtKB]; S-adenosyl-L-methionine-dependent methyltransferase involved in the biosynthesis of wybutosine, a hyper modified guanosine with a tricyclic base located at position 37 of eukaryotic phenylalanine tRNA (tRNA(Phe)) that contributes to maintenance of the translational reading frame. Catalyzes the methylation of 4-demethylwyosine, generating intermediates required for the formation of mature wybutosine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008175 tRNA methyltransferase activity;GO:0008168 methyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0030488 tRNA methylation;GO:0031591 wybutosine biosynthetic process;GO:0008033 tRNA processing;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q19QT9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6UAQ8-1", "uniprot_id": [ { "id": "ETFB_PIG", "url": "https://www.uniprot.org/uniprot/Q6UAQ8", "type": "external" } ], "mass": 27764.0, "length": 255, "protein_name": "Electron transfer flavoprotein subunit beta", "gene_name": "ETFB", "organism": "Pig", "refseq_name": "electron transfer flavoprotein subunit beta", "refseq_ac": [ { "id": "NP_001192208", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192208", "type": "external" } ], "gene_names_uniprotkb": "ETFB", "gene_names_refseq": "ETFB", "protein_names_uniprotkb": "Electron transfer flavoprotein subunit beta; Beta-ETF", "protein_names_refseq": "beta-ETF; electron transfer flavoprotein beta subunit; electron transfer flavoprotein subunit beta", "tax_id": 9823, "disease": "", "pathway": " (ssc:396614); (R-SSC-611105); (R-SSC-8876725)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "32543654;6847633", "class_list": "", "function": "Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase. Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism. ETFB binds an AMP molecule that probably has a purely structural role., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0009055 electron transfer activity;GO:0000166 nucleotide binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0045251 electron transfer flavoprotein complex", "go_biological_process": "GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0022904 respiratory electron transport chain;GO:0009063 amino acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q6UAQ8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6QGC0-1", "uniprot_id": [ { "id": "PDLI3_PIG", "url": "https://www.uniprot.org/uniprot/Q6QGC0", "type": "external" } ], "mass": 39546.0, "length": 365, "protein_name": "PDZ and LIM domain protein 3", "gene_name": "PDLIM3", "organism": "Pig", "refseq_name": "PDZ and LIM domain protein 3", "refseq_ac": [ { "id": "NP_001001637", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001637", "type": "external" } ], "gene_names_uniprotkb": "PDLIM3", "gene_names_refseq": "LIM; PDLIM3", "protein_names_uniprotkb": "PDZ and LIM domain protein 3; Actinin-associated LIM protein; Alpha-actinin-2-associated LIM protein", "protein_names_refseq": "PDZ and LIM domain protein 3; actinin-associated LIM protein 4; alpha-actinin-2-associated LIM protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:414421)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "May play a role in the organization of actin filament arrays within muscle cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051371 muscle alpha-actinin binding;GO:0003779 actin binding;GO:0046872 metal ion binding;GO:0008307 structural constituent of muscle", "go_cellular_component": "GO:0005829 cytosol;GO:0005912 adherens junction;GO:0001725 stress fiber;GO:0030018 Z disc;GO:0031941 filamentous actin", "go_biological_process": "GO:0007507 heart development;GO:0030036 actin cytoskeleton organization;GO:0061061 muscle structure development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6QGC0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7YS78-1", "uniprot_id": [ { "id": "ARRC_PIG", "url": "https://www.uniprot.org/uniprot/Q7YS78", "type": "external" } ], "mass": 43239.0, "length": 391, "protein_name": "Arrestin-C", "gene_name": "ARR3", "organism": "Pig", "refseq_name": "arrestin-C", "refseq_ac": [ { "id": "NP_999510", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999510", "type": "external" } ], "gene_names_uniprotkb": "ARR3", "gene_names_refseq": "ARR3", "protein_names_uniprotkb": "Arrestin-C; Cone arrestin; Retinal cone arrestin-3; cArr", "protein_names_refseq": "arrestin 3, retinal (X-arrestin); arrestin-C; cArr; cone arrestin; retinal cone arrestin-3", "tax_id": 9823, "disease": "", "pathway": " (ssc:397622)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15623797;32543654", "class_list": "", "function": "May play a role in an as yet undefined retina-specific signal transduction. Could bind to photoactivated-phosphorylated red/green opsins (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051219 phosphoprotein binding;GO:0002046 opsin binding", "go_cellular_component": "GO:0045202 synapse;GO:0001917 photoreceptor inner segment;GO:0001750 photoreceptor outer segment", "go_biological_process": "GO:0007165 signal transduction;GO:0007601 visual perception", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q7YS78-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q712P7-1", "uniprot_id": [ { "id": "MYPR_PIG", "url": "https://www.uniprot.org/uniprot/Q712P7", "type": "external" } ], "mass": 30077.0, "length": 277, "protein_name": "Myelin proteolipid protein", "gene_name": "PLP1", "organism": "Pig", "refseq_name": "myelin proteolipid protein", "refseq_ac": [ { "id": "NP_999139", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999139", "type": "external" } ], "gene_names_uniprotkb": "PLP1; PLP", "gene_names_refseq": "PLP1; PLP", "protein_names_uniprotkb": "Myelin proteolipid protein; Lipophilin; PLP", "protein_names_refseq": "myelin proteolipid protein; proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated); proteolipid protein, lipophilin", "tax_id": 9823, "disease": "", "pathway": " (ssc:397029)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10441741;32543654", "class_list": "", "function": "This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043209 myelin sheath", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q712P7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29036-1", "uniprot_id": [ { "id": "DAD1_PIG", "url": "https://www.uniprot.org/uniprot/Q29036", "type": "external" } ], "mass": 12511.0, "length": 113, "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "gene_name": "DAD1", "organism": "Pig", "refseq_name": "dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "refseq_ac": [ { "id": "NP_999109", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999109", "type": "external" } ], "gene_names_uniprotkb": "DAD1", "gene_names_refseq": "DAD1", "protein_names_uniprotkb": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; DAD-1; Defender against cell death 1; Oligosaccharyl transferase subunit DAD1", "protein_names_refseq": "DAD-1; defender against apoptotic cell death; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; oligosaccharyl transferase subunit DAD1", "tax_id": 9823, "disease": "", "pathway": " (ssc:396984); (R-SSC-9768727); (R-SSC-9931295)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008047 enzyme activator activity", "go_cellular_component": "GO:0008250 oligosaccharyltransferase complex;GO:0160226 oligosaccharyltransferase complex A;GO:0160227 oligosaccharyltransferase complex B", "go_biological_process": "GO:0006915 apoptotic process;GO:0009101 glycoprotein biosynthetic process;GO:0031647 regulation of protein stability;GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29036-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q864V5-1", "uniprot_id": [ { "id": "FUND2_PIG", "url": "https://www.uniprot.org/uniprot/Q864V5", "type": "external" } ], "mass": 20572.0, "length": 189, "protein_name": "FUN14 domain-containing protein 2", "gene_name": "FUNDC2", "organism": "Pig", "refseq_name": "FUN14 domain-containing protein 2", "refseq_ac": [ { "id": "NP_998908", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998908", "type": "external" } ], "gene_names_uniprotkb": "FUNDC2; HCBP6", "gene_names_refseq": "FUNDC2; HCBP6", "protein_names_uniprotkb": "FUN14 domain-containing protein 2; Hepatitis C virus core-binding protein 6", "protein_names_refseq": "FUN14 domain-containing protein 2; HCBP6-like protein; hepatitis C virus core-binding protein 6", "tax_id": 9823, "disease": "", "pathway": " (ssc:396564)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Binds directly and specifically 1,2-Diacyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-bisphosphate) (PIP3) leading to the recruitment of PIP3 to mitochondria and may play a role in the regulation of the platelet activation via AKT/GSK3B/cGMP signaling pathways (By similarity). May act as transcription factor that regulates SREBP1 (isoform SREBP-1C) expression in order to modulate triglyceride (TG) homeostasis in hepatocytes (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0010543 regulation of platelet activation;GO:0006351 DNA-templated transcription;GO:0000422 autophagy of mitochondrion;GO:0035356 intracellular triglyceride homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q864V5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q06AU9-1", "uniprot_id": [ { "id": "PNMT_PIG", "url": "https://www.uniprot.org/uniprot/Q06AU9", "type": "external" } ], "mass": 30879.0, "length": 283, "protein_name": "Phenylethanolamine N-methyltransferase", "gene_name": "PNMT", "organism": "Pig", "refseq_name": "phenylethanolamine N-methyltransferase", "refseq_ac": [ { "id": "NP_001116636", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116636", "type": "external" } ], "gene_names_uniprotkb": "PNMT", "gene_names_refseq": "PNMT", "protein_names_uniprotkb": "Phenylethanolamine N-methyltransferase; 2.1.1.28; Noradrenaline N-methyltransferase; PNMTase", "protein_names_refseq": "PNMTase; noradrenaline N-methyltransferase; phenylethanolamine N-methyltransferase", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144479); (R-SSC-209905)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the transmethylation of nonepinephrine (noradrenaline) to form epinephrine (adrenaline), using S-adenosyl-L-methionine as the methyl donor. Other substrates include phenylethanolamine, octopamine and normetanephrine (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004603 phenylethanolamine N-methyltransferase activity;GO:0008757 S-adenosylmethionine-dependent methyltransferase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0032259 methylation;GO:0042418 epinephrine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q06AU9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q06AV4-1", "uniprot_id": [ { "id": "ITM2C_PIG", "url": "https://www.uniprot.org/uniprot/Q06AV4", "type": "external" } ], "mass": 30472.0, "length": 269, "protein_name": "Integral membrane protein 2C", "gene_name": "ITM2C", "organism": "Pig", "refseq_name": "integral membrane protein 2C", "refseq_ac": [ { "id": "NP_001116603", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116603", "type": "external" } ], "gene_names_uniprotkb": "ITM2C", "gene_names_refseq": "ITM2C", "protein_names_uniprotkb": "Integral membrane protein 2C", "protein_names_refseq": "integral membrane protein 2C", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144481)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001540 amyloid-beta binding;GO:0005524 ATP binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005764 lysosome;GO:0005765 lysosomal membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0042985 negative regulation of amyloid precursor protein biosynthetic process;GO:0030182 neuron differentiation;GO:0010977 negative regulation of neuron projection development;GO:2001238 positive regulation of extrinsic apoptotic signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q06AV4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q56P28-1", "uniprot_id": [ { "id": "PRAF3_PIG", "url": "https://www.uniprot.org/uniprot/Q56P28", "type": "external" } ], "mass": 21541.0, "length": 188, "protein_name": "PRA1 family protein 3", "gene_name": "ARL6IP5", "organism": "Pig", "refseq_name": "PRA1 family protein 3", "refseq_ac": [ { "id": "NP_001041538", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001041538", "type": "external" } ], "gene_names_uniprotkb": "ARL6IP5; PRAF3", "gene_names_refseq": "ARL6IP5", "protein_names_uniprotkb": "PRA1 family protein 3; ADP-ribosylation factor-like protein 6-interacting protein 5; ARL-6-interacting protein 5; Aip-5", "protein_names_refseq": "ADP-ribosylation factor-like protein 6-interacting protein 5; ADP-ribosylation-like factor 6 interacting protein 5; ARL-6-interacting protein 5; PRA1 family protein 3; PRA1 family protein-like protein; aip-5", "tax_id": 9823, "disease": "", "pathway": " (ssc:595127); (R-SSC-210500)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate in a PKC activity-dependent manner. Plays a role in the retention of SLC1A1/EAAC1 in the endoplasmic reticulum., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane;GO:0099523 presynaptic cytosol", "go_biological_process": "GO:0002037 negative regulation of L-glutamate import across plasma membrane;GO:0051051 negative regulation of transport;GO:0015813 L-glutamate transmembrane transport;GO:0043065 positive regulation of apoptotic process;GO:0010917 negative regulation of mitochondrial membrane potential", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q56P28-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7PCJ9-1", "uniprot_id": [ { "id": "SAT2_PIG", "url": "https://www.uniprot.org/uniprot/Q7PCJ9", "type": "external" } ], "mass": 19171.0, "length": 170, "protein_name": "Thialysine N-epsilon-acetyltransferase", "gene_name": "SAT2", "organism": "Pig", "refseq_name": "thialysine N-epsilon-acetyltransferase", "refseq_ac": [ { "id": "NP_001123434", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001123434", "type": "external" } ], "gene_names_uniprotkb": "SAT2; SSAT2", "gene_names_refseq": "SAT2; SSAT-2; SSAT2", "protein_names_uniprotkb": "Thialysine N-epsilon-acetyltransferase; 2.3.1.-; 2.3.1.57; Diamine acetyltransferase 2; SSAT-2; Spermidine/spermine N(1)-acetyltransferase 2", "protein_names_refseq": "Diamine acetyltransferase 2; polyamine N-acetyltransferase 2; spermidine/spermine N-1 acetyltransferase 2; thialysine N-epsilon-acetyltransferase", "tax_id": 9823, "disease": "", "pathway": " (ssc:100170117)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12803540;32543654", "class_list": "", "function": "Catalyzes the N-acetylation of the amino acid thialysine (S-(2-aminoethyl)-L-cysteine), a L-lysine analog with the 4-methylene group substituted with a sulfur. May also catalyze acetylation of polyamines, such as norspermidine, spermidine or spermine. However, ability to acetylate polyamines is weak, suggesting that it does not act as a diamine acetyltransferase in vivo., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008080 N-acetyltransferase activity;GO:0042802 identical protein binding;GO:0004145 diamine N-acetyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006595 polyamine metabolic process;GO:0032918 spermidine acetylation;GO:0032919 spermine acetylation;GO:0032920 putrescine acetylation;GO:0046204 nor-spermidine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q7PCJ9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q2TLZ2-1", "uniprot_id": [ { "id": "MACOI_PIG", "url": "https://www.uniprot.org/uniprot/Q2TLZ2", "type": "external" } ], "mass": 76148.0, "length": 664, "protein_name": "Macoilin", "gene_name": "MACO1", "organism": "Pig", "refseq_name": "macoilin", "refseq_ac": [ { "id": "NP_001033735", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033735", "type": "external" } ], "gene_names_uniprotkb": "MACO1; TMEM57", "gene_names_refseq": "MACO1; TMEM57", "protein_names_uniprotkb": "Macoilin; Macoilin-1; Transmembrane protein 57", "protein_names_refseq": "macoilin; transmembrane protein 57", "tax_id": 9823, "disease": "", "pathway": " (ssc:654414); (R-SSC-8980692); (R-SSC-9013106)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays a role in the regulation of neuronal activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0030424 axon;GO:0031965 nuclear membrane;GO:0045202 synapse;GO:0044306 neuron projection terminus;GO:0030867 rough endoplasmic reticulum membrane", "go_biological_process": "GO:0023041 neuronal signal transduction;GO:0006935 chemotaxis;GO:0007420 brain development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2TLZ2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q684M6-1", "uniprot_id": [ { "id": "Q684M6_PIG", "url": "https://www.uniprot.org/uniprot/Q684M6", "type": "external" } ], "mass": 44490.0, "length": 380, "protein_name": "Hsp90 co-chaperone Cdc37", "gene_name": "CDC37", "organism": "Pig", "refseq_name": "hsp90 co-chaperone Cdc37", "refseq_ac": [ { "id": "NP_001116568", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116568", "type": "external" } ], "gene_names_uniprotkb": "CDC37", "gene_names_refseq": "CDC37", "protein_names_uniprotkb": "Hsp90 co-chaperone Cdc37; Hsp90 chaperone protein kinase-targeting subunit", "protein_names_refseq": "CDC37 cell division cycle 37 protein; cell division cycle 37 homolog; hsp90 co-chaperone Cdc37", "tax_id": 9823, "disease": "", "pathway": " (ssc:100141402); (R-SSC-1227986); (R-SSC-5675482); (R-SSC-8863795); (R-SSC-9013418); (R-SSC-9652282)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1V502", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0051082 unfolded protein binding;GO:0051087 protein-folding chaperone binding;GO:0031072 heat shock protein binding;GO:0019887 protein kinase regulator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:1990565 HSP90-CDC37 chaperone complex", "go_biological_process": "GO:0050821 protein stabilization;GO:0006457 protein folding;GO:0051301 cell division;GO:0010608 post-transcriptional regulation of gene expression;GO:1905091 positive regulation of type 2 mitophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q684M6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5D144-1", "uniprot_id": [ { "id": "TFAM_PIG", "url": "https://www.uniprot.org/uniprot/Q5D144", "type": "external" } ], "mass": 28726.0, "length": 246, "protein_name": "Transcription factor A, mitochondrial", "gene_name": "TFAM", "organism": "Pig", "refseq_name": "transcription factor A, mitochondrial precursor", "refseq_ac": [ { "id": "NP_001123683", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001123683", "type": "external" } ], "gene_names_uniprotkb": "TFAM", "gene_names_refseq": "TFAM", "protein_names_uniprotkb": "Transcription factor A, mitochondrial; mtTFA", "protein_names_refseq": "mitochondrial transcription factor A; mtTFA; transcription factor A, mitochondrial precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397279); (R-SSC-163282); (R-SSC-9837999)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "18636550;32543654", "class_list": "", "function": "Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA. In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA., [UniProtKB, UniProtKB]; TFAM may exert a critical role in porcine gametogenesis and preimplantation embryo development., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001018 mitochondrial promoter sequence-specific DNA binding;GO:0003682 chromatin binding;GO:0034246 mitochondrial transcription factor activity;GO:0003677 DNA binding", "go_cellular_component": "GO:0042645 mitochondrial nucleoid;GO:0032991 protein-containing complex;GO:0005634 nucleus", "go_biological_process": "GO:0006391 transcription initiation at mitochondrial promoter;GO:0006390 mitochondrial transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q5D144-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q52NJ3-1", "uniprot_id": [ { "id": "SAR1A_PIG", "url": "https://www.uniprot.org/uniprot/Q52NJ3", "type": "external" } ], "mass": 22409.0, "length": 198, "protein_name": "Small COPII coat GTPase SAR1A", "gene_name": "SAR1A", "organism": "Pig", "refseq_name": "small COPII coat GTPase SAR1A", "refseq_ac": [ { "id": "NP_001026956", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026956", "type": "external" } ], "gene_names_uniprotkb": "SAR1A", "gene_names_refseq": "SAR1A", "protein_names_uniprotkb": "Small COPII coat GTPase SAR1A; 3.6.5.2", "protein_names_refseq": "GTP-binding protein SAR1a; SAR1 homolog A; small COPII coat GTPase SAR1A", "tax_id": 9823, "disease": "", "pathway": " (ssc:595115)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Small GTPase that cycles between an active GTP-bound and an inactive GDP-bound state and mainly functions in vesicle-mediated endoplasmic reticulum (ER) to Golgi transport. The active GTP-bound form inserts into the endoplasmic reticulum membrane where it recruits the remainder of the coat protein complex II/COPII. The coat protein complex II assembling and polymerizing on endoplasmic reticulum membrane is responsible for both the sorting of cargos and the deformation and budding of membranes into vesicles destined to the Golgi. The GTPase activity of SAR1 by controlling the timing of COPII budding regulates the size of the formed vesicles and is important for cargo selection depending on their size. Together with SEC16A, forms the organized scaffold defining endoplasmic reticulum exit sites (ERES), some specific domains of the endoplasmic reticulum where COPII vesicles form. In addition to its role in vesicle trafficking, can also function as a leucine sensor regulating TORC1 signaling and more indirectly cellular metabolism, growth and survival. In absence of leucine, interacts with the GATOR2 complex via MIOS and inhibits TORC1 signaling. The binding of leucine abrogates the interaction with GATOR2 and the inhibition of the TORC1 signaling. This function is completely independent of the GTPase activity of SAR1B., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0003925 G protein activity;GO:0140785 amino acid sensor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:0032580 Golgi cisterna membrane;GO:0070971 endoplasmic reticulum exit site", "go_biological_process": "GO:0090110 COPII-coated vesicle cargo loading;GO:0006886 intracellular protein transport;GO:0061024 membrane organization;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0048208 COPII vesicle coating", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q52NJ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6ITT4-1", "uniprot_id": [ { "id": "MAGD1_PIG", "url": "https://www.uniprot.org/uniprot/Q6ITT4", "type": "external" } ], "mass": 86533.0, "length": 784, "protein_name": "Melanoma-associated antigen D1", "gene_name": "MAGED1", "organism": "Pig", "refseq_name": "melanoma-associated antigen D1", "refseq_ac": [ { "id": "NP_001001860", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001860", "type": "external" } ], "gene_names_uniprotkb": "MAGED1", "gene_names_refseq": "MAGED1", "protein_names_uniprotkb": "Melanoma-associated antigen D1; MAGE-D1 antigen", "protein_names_refseq": "MAGE-D1 antigen; melanoma antigen family D, 1; melanoma-associated antigen D1", "tax_id": 9823, "disease": "", "pathway": " (ssc:414852)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rhythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as BMAL1 and NFIL3, induced, or NR1D1, repressed (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0000785 chromatin;GO:0032991 protein-containing complex", "go_biological_process": "GO:0050680 negative regulation of epithelial cell proliferation;GO:0032922 circadian regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6ITT4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9MYT8-1", "uniprot_id": [ { "id": "ATP5I_PIG", "url": "https://www.uniprot.org/uniprot/Q9MYT8", "type": "external" } ], "mass": 8232.0, "length": 71, "protein_name": "ATP synthase F(0) complex subunit e, mitochondrial", "gene_name": "ATP5ME", "organism": "Pig", "refseq_name": "ATP synthase F(0) complex subunit e, mitochondrial", "refseq_ac": [ { "id": "NP_999080", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999080", "type": "external" } ], "gene_names_uniprotkb": "ATP5ME; ATP5I", "gene_names_refseq": "ATP5I; ATP5ME", "protein_names_uniprotkb": "ATP synthase F(0) complex subunit e, mitochondrial; ATP synthase membrane subunit e; ATPase subunit e", "protein_names_refseq": "ATP synthase F(0) complex subunit e, mitochondrial; ATP synthase subunit e, mitochondrial; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E; ATP synthase, H+ transporting, mitochondrial Fo complex subunit E; ATPase subunit e; H+-transporting ATP synthase", "tax_id": 9823, "disease": "", "pathway": " (ssc:396950)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Subunit e, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1XQR5", "ec_number_list": [], "go_molecular_function": "GO:0046933 proton-transporting ATP synthase activity, rotational mechanism", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0042776 proton motive force-driven mitochondrial ATP synthesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9MYT8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6TYI6-1", "uniprot_id": [ { "id": "TREM1_PIG", "url": "https://www.uniprot.org/uniprot/Q6TYI6", "type": "external" } ], "mass": 26428.0, "length": 238, "protein_name": "Triggering receptor expressed on myeloid cells 1", "gene_name": "TREM1", "organism": "Pig", "refseq_name": "triggering receptor expressed on myeloid cells 1 precursor", "refseq_ac": [ { "id": "NP_998921", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998921", "type": "external" } ], "gene_names_uniprotkb": "TREM1", "gene_names_refseq": "TREM-1; TREM1", "protein_names_uniprotkb": "Triggering receptor expressed on myeloid cells 1; TREM-1", "protein_names_refseq": "triggering receptor expressed on myeloid cells 1 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:396601)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15451618;32543654", "class_list": "", "function": "Cell surface receptor that plays important roles in innate and adaptive immunity by amplifying inflammatory responses. Upon activation by various ligands such as PGLYRP1, HMGB1 or HSP70, multimerizes and forms a complex with transmembrane adapter TYROBP/DAP12. In turn, initiates a SYK-mediated cascade of tyrosine phosphorylation, activating multiple downstream mediators such as BTK, MAPK1, MAPK3 or phospholipase C-gamma. This cascade promotes the neutrophil- and macrophage-mediated release of pro-inflammatory cytokines and/or chemokines, as well as their migration and thereby amplifies inflammatory responses that are triggered by bacterial and fungal infections. By also promoting the amplification of inflammatory signals that are initially triggered by Toll-like receptor (TLR) and NOD-like receptor engagement, plays a major role in the pathophysiology of acute and chronic inflammatory diseases of different etiologies including septic shock and atherosclerosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0097110 scaffold protein binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0045087 innate immune response;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q6TYI6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6XQG9-1", "uniprot_id": [ { "id": "G3ST2_PIG", "url": "https://www.uniprot.org/uniprot/Q6XQG9", "type": "external" } ], "mass": 45769.0, "length": 398, "protein_name": "Galactose-3-O-sulfotransferase 2", "gene_name": "D2HGDH; GAL3ST2", "organism": "Pig", "refseq_name": "galactose-3-O-sulfotransferase 2", "refseq_ac": [ { "id": "NP_998943", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998943", "type": "external" } ], "gene_names_uniprotkb": "D2HGDH; GAL3ST2; GAL3ST2", "gene_names_refseq": "GAL3ST2; pGal3ST", "protein_names_uniprotkb": "Galactose-3-O-sulfotransferase 2; 2.8.2.-; Beta-galactose-3-O-sulfotransferase 2; Gal 3-O-sulphotransferase; Gal-beta-1, 3-GalNAc 3'-sulfotransferase 2; Gal3ST-2; pGal3ST", "protein_names_refseq": "beta-galactose-3-O-sulfotransferase 2; gal 3-O-sulphotransferase; gal-beta-1, 3-GalNAc 3'-sulfotransferase 2; gal3ST-2; galactose-3-O-sulfotransferase 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:396666)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15926885;32543654", "class_list": "", "function": "Catalyzes the transfer of a sulfate group from 3'-phosphoadenylyl sulfate (PAPS) to the C-3 hydroxyl group of terminal non-reducing beta-galactosyl residues (PubMed:15926885). Acts preferentially to core 1 (Gal-beta-1,3-GalNAc-alpha-1-R) chains, although type 1 (Gal-beta-1,3-GlcNAc-R) and type 2 (Gal-beta-1,4-GlcNAc-R) chains could be utilized but with lower efficiency than core 1 (PubMed:15926885). Displays species-dependent substrate specificity (PubMed:15926885). Participates in galactose sulfation (PubMed:15926885)., [UniProtKB, PubMed]; The substrate specificity and cofactor requirements of human, porcine, and murine GAL3ST are reported, [RefSeq, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0050694 galactose 3-O-sulfotransferase activity;GO:0001733 galactosylceramide sulfotransferase activity", "go_cellular_component": "GO:0032580 Golgi cisterna membrane;GO:0000139 Golgi membrane", "go_biological_process": "GO:0051923 sulfation;GO:0009101 glycoprotein biosynthetic process;GO:0009247 glycolipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q6XQG9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6DUB7-1", "uniprot_id": [ { "id": "STMN1_PIG", "url": "https://www.uniprot.org/uniprot/Q6DUB7", "type": "external" } ], "mass": 17303.0, "length": 149, "protein_name": "Stathmin", "gene_name": "STMN1", "organism": "Pig", "refseq_name": "stathmin", "refseq_ac": [ { "id": "NP_001009582", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009582", "type": "external" } ], "gene_names_uniprotkb": "STMN1", "gene_names_refseq": "STMN1", "protein_names_uniprotkb": "Stathmin", "protein_names_refseq": "stathmin", "tax_id": 9823, "disease": "", "pathway": " (ssc:494463)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules (By similarity). Its phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015631 tubulin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0043005 neuron projection", "go_biological_process": "GO:0031110 regulation of microtubule polymerization or depolymerization;GO:0031175 neuron projection development;GO:0007019 microtubule depolymerization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6DUB7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q76KD0-1", "uniprot_id": [ { "id": "Q76KD0_PIG", "url": "https://www.uniprot.org/uniprot/Q76KD0", "type": "external" } ], "mass": 41784.0, "length": 368, "protein_name": "Cytokine receptor common subunit gamma", "gene_name": "IL2RG", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IL2RG", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytokine receptor common subunit gamma; Interleukin-2 receptor subunit gamma; gammaC; p64", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1266695); (R-SSC-5673001); (R-SSC-6785807); (R-SSC-8983432); (R-SSC-8985947); (R-SSC-9020558); (R-SSC-9020958); (R-SSC-912526)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Common subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F6PZ59", "ec_number_list": [], "go_molecular_function": "GO:0004896 cytokine receptor activity;GO:0015026 coreceptor activity;GO:0019955 cytokine binding;GO:0019976 interleukin-2 binding;GO:0042010 interleukin-15 receptor activity", "go_cellular_component": "GO:0016020 membrane;GO:0043235 receptor complex;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0038110 interleukin-2-mediated signaling pathway;GO:0019725 cellular homeostasis;GO:0050766 positive regulation of phagocytosis;GO:0038111 interleukin-7-mediated signaling pathway;GO:0019221 cytokine-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q76KD0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MJ76-1", "uniprot_id": [ { "id": "FETA_PIG", "url": "https://www.uniprot.org/uniprot/Q8MJ76", "type": "external" } ], "mass": 68625.0, "length": 610, "protein_name": "Alpha-fetoprotein", "gene_name": "AFP", "organism": "Pig", "refseq_name": "alpha-fetoprotein precursor", "refseq_ac": [ { "id": "NP_999482", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999482", "type": "external" } ], "gene_names_uniprotkb": "AFP", "gene_names_refseq": "AFP", "protein_names_uniprotkb": "Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin", "protein_names_refseq": "alpha-1-fetoprotein; alpha-fetoglobulin; alpha-fetoprotein precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397586); (R-SSC-381426); (R-SSC-8957275)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "12464028;32543654", "class_list": "", "function": "Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0036094 small molecule binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm", "go_biological_process": "GO:0031667 response to nutrient levels", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8MJ76-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95JC8-1", "uniprot_id": [ { "id": "ARGI1_PIG", "url": "https://www.uniprot.org/uniprot/Q95JC8", "type": "external" } ], "mass": 35018.0, "length": 322, "protein_name": "Arginase-1", "gene_name": "ARG1", "organism": "Pig", "refseq_name": "arginase-1", "refseq_ac": [ { "id": "NP_999213", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999213", "type": "external" } ], "gene_names_uniprotkb": "ARG1", "gene_names_refseq": "ARG1", "protein_names_uniprotkb": "Arginase-1; 3.5.3.1; Liver-type arginase; Type I arginase", "protein_names_refseq": "arginase I; arginase, liver; arginase-1; liver-type arginase; type I arginase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397115); (R-SSC-6798695); (R-SSC-70635)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "17379953;19293328;32543654;34206713", "class_list": "", "function": "Proteome Analysis in PAM Cells Reveals That African Swine Fever Virus Can Regulate the Level of Intracellular Polyamines to Facilitate Its Own Replication through ARG1. Publication Status: Online-Only, [RefSeq, PubMed]; Results show that ischemia markedly potentiated the expression of arginase-1, and also induced the SOD2 in the wound tissue., [RefSeq, PubMed]; The immunosuppressive effect of a purified substance (ISF) in the culture medium of neonatal pig liver fragments was due to arginase activity that decreased arginine concentration in culture medium, not to another function of ISF., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030145 manganese ion binding;GO:0004053 arginase activity;GO:0046872 metal ion binding;GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005615 extracellular space", "go_biological_process": "GO:0042127 regulation of cell population proliferation;GO:0000050 urea cycle;GO:0006525 arginine metabolic process;GO:0042832 defense response to protozoan;GO:0046007 negative regulation of activated T cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q95JC8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9TSV6-1", "uniprot_id": [ { "id": "VATG2_PIG", "url": "https://www.uniprot.org/uniprot/Q9TSV6", "type": "external" } ], "mass": 13579.0, "length": 118, "protein_name": "V-type proton ATPase subunit G 2", "gene_name": "ATP6V1G2", "organism": "Pig", "refseq_name": "V-type proton ATPase subunit G 2", "refseq_ac": [ { "id": "NP_001138852", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138852", "type": "external" } ], "gene_names_uniprotkb": "ATP6V1G2; ATP6G2", "gene_names_refseq": "ATP6G2; ATP6V1G2", "protein_names_uniprotkb": "V-type proton ATPase subunit G 2; V-ATPase subunit G 2; Vacuolar proton pump subunit G 2", "protein_names_refseq": "ATPase, H+ transporting, lysosomal V1 subunit G2; V-ATPase subunit G 2; V-type proton ATPase subunit G 2; vacuolar proton pump subunit G 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100152358); (R-SSC-1222556); (R-SSC-77387); (R-SSC-917977); (R-SSC-9639288); (R-SSC-983712)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "11169259;32543654", "class_list": "", "function": "Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046961 proton-transporting ATPase activity, rotational mechanism", "go_cellular_component": "GO:0042470 melanosome;GO:0030665 clathrin-coated vesicle membrane;GO:0030672 synaptic vesicle membrane;GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0012505 endomembrane system", "go_biological_process": "GO:0097401 synaptic vesicle lumen acidification", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9TSV6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29361-1", "uniprot_id": [ { "id": "RL35_PIG", "url": "https://www.uniprot.org/uniprot/Q29361", "type": "external" } ], "mass": 14550.0, "length": 123, "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "RPL35", "organism": "Pig", "refseq_name": "large ribosomal subunit protein uL29", "refseq_ac": [ { "id": "NP_999491", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999491", "type": "external" } ], "gene_names_uniprotkb": "RPL35", "gene_names_refseq": "RPL35", "protein_names_uniprotkb": "Large ribosomal subunit protein uL29; 60S ribosomal protein L35", "protein_names_refseq": "60S ribosomal protein L35; large ribosomal subunit protein uL29", "tax_id": 9823, "disease": "", "pathway": " (ssc:397598); (R-SSC-156827); (R-SSC-1799339); (R-SSC-6791226); (R-SSC-72689); (R-SSC-72706); (R-SSC-975956); (R-SSC-975957); (R-SSC-9954709); (R-SSC-9954714); (R-SSC-9954716)", "pathway_count": 11, "publication_count": 4, "publication_id_list": "11913794;17416745;32543654;8672129", "class_list": "", "function": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1XQU6;A2BD10;Q9BGU2", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane;GO:0022625 cytosolic large ribosomal subunit;GO:0015934 large ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q29361-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q06AV1-1", "uniprot_id": [ { "id": "NNMT_PIG", "url": "https://www.uniprot.org/uniprot/Q06AV1", "type": "external" } ], "mass": 29479.0, "length": 264, "protein_name": "Nicotinamide N-methyltransferase", "gene_name": "NNMT", "organism": "Pig", "refseq_name": "nicotinamide N-methyltransferase", "refseq_ac": [ { "id": "NP_001116618", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116618", "type": "external" } ], "gene_names_uniprotkb": "NNMT", "gene_names_refseq": "NNMT", "protein_names_uniprotkb": "Nicotinamide N-methyltransferase; 2.1.1.1", "protein_names_refseq": "nicotinamide N-methyltransferase", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144485)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the N-methylation of nicotinamide using the universal methyl donor S-adenosyl-L-methionine to form N1-methylnicotinamide and S-adenosyl-L-homocysteine, a predominant nicotinamide/vitamin B3 clearance pathway (By similarity). Plays a central role in regulating cellular methylation potential, by consuming S-adenosyl-L-methionine and limiting its availability for other methyltransferases (By similarity). Actively mediates genome-wide epigenetic and transcriptional changes through hypomethylation of repressive chromatin marks, such as H3K27me3 (By similarity). In a developmental context, contributes to low levels of the repressive histone marks that characterize pluripotent embryonic stem cell pre-implantation state (By similarity). Acts as a metabolic regulator primarily on white adipose tissue energy expenditure as well as hepatic gluconeogenesis and cholesterol biosynthesis (By similarity). In white adipocytes, regulates polyamine flux by consuming S-adenosyl-L-methionine which provides for propylamine group in polyamine biosynthesis, whereas by consuming nicotinamide controls NAD(+) levels through the salvage pathway (By similarity). Via its product N1-methylnicotinamide regulates protein acetylation in hepatocytes, by repressing the ubiquitination and increasing the stability of SIRT1 deacetylase (By similarity). Can also N-methylate other pyridines structurally related to nicotinamide and play a role in xenobiotic detoxification (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008112 nicotinamide N-methyltransferase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0032259 methylation;GO:0045722 positive regulation of gluconeogenesis;GO:0090312 positive regulation of protein deacetylation;GO:0006769 nicotinamide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q06AV1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q06AV5-1", "uniprot_id": [ { "id": "ID4_PIG", "url": "https://www.uniprot.org/uniprot/Q06AV5", "type": "external" } ], "mass": 16591.0, "length": 161, "protein_name": "DNA-binding protein inhibitor ID-4", "gene_name": "ID4", "organism": "Pig", "refseq_name": "DNA-binding protein inhibitor ID-4", "refseq_ac": [ { "id": "NP_001116602", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116602", "type": "external" } ], "gene_names_uniprotkb": "ID4", "gene_names_refseq": "ID4", "protein_names_uniprotkb": "DNA-binding protein inhibitor ID-4; Inhibitor of DNA binding 4; Inhibitor of differentiation 4", "protein_names_refseq": "DNA-binding protein inhibitor ID-4; inhibitor of DNA binding 4, HLH protein; inhibitor of DNA binding 4, dominant negative helix-loop-helix protein; inhibitor of differentiation 4", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144508)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q06AV5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08092-1", "uniprot_id": [ { "id": "CNN1_PIG", "url": "https://www.uniprot.org/uniprot/Q08092", "type": "external" } ], "mass": 33226.0, "length": 297, "protein_name": "Calponin-1", "gene_name": "CNN1", "organism": "Pig", "refseq_name": "calponin-1", "refseq_ac": [ { "id": "NP_999043", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999043", "type": "external" } ], "gene_names_uniprotkb": "CNN1", "gene_names_refseq": "CNN1; Calponin-1", "protein_names_uniprotkb": "Calponin-1; Basic calponin; Calponin H1, smooth muscle", "protein_names_refseq": "basic calponin; calponin H1, smooth muscle; calponin-1; h1-calponin", "tax_id": 9823, "disease": "", "pathway": " (ssc:396911)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8370452", "class_list": "", "function": "Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0051015 actin filament binding", "go_cellular_component": "", "go_biological_process": "GO:0031032 actomyosin structure organization;GO:0051764 actin crosslink formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q08092-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q08094-1", "uniprot_id": [ { "id": "CNN2_PIG", "url": "https://www.uniprot.org/uniprot/Q08094", "type": "external" } ], "mass": 32030.0, "length": 296, "protein_name": "Calponin-2", "gene_name": "CNN2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CNN2", "gene_names_refseq": "", "protein_names_uniprotkb": "Calponin-2; Calponin H2, smooth muscle; Neutral calponin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8370452", "class_list": "", "function": "Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0051015 actin filament binding", "go_cellular_component": "", "go_biological_process": "GO:0031032 actomyosin structure organization;GO:0051764 actin crosslink formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q08094-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q09138-1", "uniprot_id": [ { "id": "AAKG1_PIG", "url": "https://www.uniprot.org/uniprot/Q09138", "type": "external" } ], "mass": 37415.0, "length": 330, "protein_name": "5'-AMP-activated protein kinase subunit gamma-1", "gene_name": "PRKAG1", "organism": "Pig", "refseq_name": "5'-AMP-activated protein kinase subunit gamma-1", "refseq_ac": [ { "id": "NP_001001642", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001642", "type": "external" } ], "gene_names_uniprotkb": "PRKAG1", "gene_names_refseq": "PRKAG1", "protein_names_uniprotkb": "5'-AMP-activated protein kinase subunit gamma-1; 38 kDa subunit; AMPK gamma1; AMPK subunit gamma-1; AMPKg", "protein_names_refseq": "38 kDa subunit; 5'-AMP-activated protein kinase gamma-1 subunit; 5'-AMP-activated protein kinase subunit gamma-1; AMPK gamma1; AMPK subunit gamma-1; AMPKg", "tax_id": 9823, "disease": "", "pathway": " (ssc:414426); (R-SSC-1632852); (R-SSC-380972); (R-SSC-5628897); (R-SSC-6804756); (R-SSC-9931269)", "pathway_count": 6, "publication_count": 3, "publication_id_list": "15025572;15222307;7961907", "class_list": "", "function": "AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive., [UniProtKB, UniProtKB]; Mapped on porcine chromosome 5, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6X275", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0016208 AMP binding;GO:0043531 ADP binding;GO:0019887 protein kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0031588 nucleotide-activated protein kinase complex", "go_biological_process": "GO:0006110 regulation of glycolytic process;GO:0006633 fatty acid biosynthetic process;GO:0042149 cellular response to glucose starvation;GO:0045722 positive regulation of gluconeogenesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q09138-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q09821-1", "uniprot_id": [ { "id": "STP4_PIG", "url": "https://www.uniprot.org/uniprot/Q09821", "type": "external" } ], "mass": 16223.0, "length": 138, "protein_name": "Spermatid nuclear transition protein 4", "gene_name": "TNP4", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TNP4", "gene_names_refseq": "", "protein_names_uniprotkb": "Spermatid nuclear transition protein 4; STP-4; TP-4; TP4", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "7588743", "class_list": "", "function": "Involved in nuclear basic protein transition: histones are replaced by spermatid specific proteins which are themselves replaced by protamines in late spermatids., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000786 nucleosome", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q09821-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q0MVN8-1", "uniprot_id": [ { "id": "QOR_PIG", "url": "https://www.uniprot.org/uniprot/Q0MVN8", "type": "external" } ], "mass": 34997.0, "length": 329, "protein_name": "Zeta-crystallin", "gene_name": "CRYZ", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CRYZ", "gene_names_refseq": "", "protein_names_uniprotkb": "Zeta-crystallin; 1.6.5.5; NADPH:quinone reductase; Quinone oxidoreductase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Multifunctional crystallin endowed with unrelated mRNA stabilization and enzymatic oxidoreductase activities. Binds (AU)-rich elements (ARE) in the 3'-UTR of target mRNA to enhance their stability (By similarity). Upon metabolic acidosis, stabilizes the mRNA encoding SLC12A1 a cotransporter involved in transepithelial NH4(+) reabsorption in the medullary thick ascending limb in kidney (By similarity). In response to acidosis, also participates to the adaptive increase in renal ammoniagenesis by stabilizing the mRNAs of enzymes involved in glutamine catabolism (By similarity). By the same mechanism, it also regulates the expression of the antiapoptotic protein BCL2. Beside its mRNA stabilization activity, also catalyzes the reduction of orthoquinones such as 1,2-naphthoquinone or 9,10-phenanthrenequinone in the presence of NADPH in vitro and could be involved in the detoxification of xenobiotics and protection against oxidative stress (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003960 quinone reductase (NADPH) activity;GO:0003730 mRNA 3'-UTR binding;GO:0070402 NADPH binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0042178 xenobiotic catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0MVN8-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q19QU3-1", "uniprot_id": [ { "id": "ZRAB2_PIG", "url": "https://www.uniprot.org/uniprot/Q19QU3", "type": "external" } ], "mass": 37111.0, "length": 328, "protein_name": "Zinc finger Ran-binding domain-containing protein 2", "gene_name": "ZRANB2", "organism": "Pig", "refseq_name": "zinc finger Ran-binding domain-containing protein 2", "refseq_ac": [ { "id": "NP_001038047", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038047", "type": "external" } ], "gene_names_uniprotkb": "ZRANB2; ZNF265", "gene_names_refseq": "ZNF265; ZRANB2", "protein_names_uniprotkb": "Zinc finger Ran-binding domain-containing protein 2; Zinc finger protein 265", "protein_names_refseq": "zinc finger Ran-binding domain-containing protein 2; zinc finger protein 265", "tax_id": 9823, "disease": "", "pathway": " (ssc:733651)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16978188", "class_list": "", "function": "Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3' (By similarity). May interfere with constitutive 5'-splice site selection (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0001530 lipopolysaccharide binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q19QU3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1ELV2-1", "uniprot_id": [ { "id": "Q1ELV2_PIG", "url": "https://www.uniprot.org/uniprot/Q1ELV2", "type": "external" } ], "mass": 34650.0, "length": 320, "protein_name": "Melanocyte-stimulating hormone receptor", "gene_name": "MC1R", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "MC1R", "gene_names_refseq": "", "protein_names_uniprotkb": "Melanocyte-stimulating hormone receptor; MSH-R; Melanocortin receptor 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-375276)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "G protein-coupled receptor that binds melanocyte-stimulating hormones (alpha, beta, and gamma-MSH) and adrenocorticotropic hormone/ACTH, which are peptide products of the POMC precursor protein. Upon activation, MC1R couples with the G(s) protein, stimulating adenylate cyclase and activating the cAMP-dependent signaling pathway. This activation promotes melanogenesis, resulting in the production of eumelanin (black/brown) and pheomelanin (red/yellow) in melanocytes. MC1R interacts with G protein-coupled receptor opsin 3/OPN3, which couples to G(i) proteins and inhibits the alpha-MSH-induced cAMP response, thereby reducing melanin synthesis. Binding to Agouti/ASP precludes alpha-MSH-induced signaling, thereby downregulating melanogenesis. Additionally, interaction with MGRN1 displaces the G(s) protein, further suppressing MC1R signaling., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0004978 corticotropin receptor activity;GO:0004980 melanocyte-stimulating hormone receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0035556 intracellular signal transduction;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0032720 negative regulation of tumor necrosis factor production;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1ELV2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q1W0Y2-1", "uniprot_id": [ { "id": "COX7C_PIG", "url": "https://www.uniprot.org/uniprot/Q1W0Y2", "type": "external" } ], "mass": 7347.0, "length": 63, "protein_name": "Cytochrome c oxidase subunit 7C, mitochondrial", "gene_name": "COX7C", "organism": "Pig", "refseq_name": "cytochrome c oxidase subunit 7C, mitochondrial precursor", "refseq_ac": [ { "id": "NP_001090943", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001090943", "type": "external" } ], "gene_names_uniprotkb": "COX7C; COX7C1", "gene_names_refseq": "COX7C1; COX7C", "protein_names_uniprotkb": "Cytochrome c oxidase subunit 7C, mitochondrial; Cytochrome c oxidase polypeptide VIIc", "protein_names_refseq": "cytochrome c oxidase polypeptide VIIc; cytochrome c oxidase subunit 7C, mitochondrial precursor; cytochrome c oxidase subunit 7C, mitochondrial; cytochrome c oxidase subunit VIIc", "tax_id": 9823, "disease": "", "pathway": " (ssc:100037990); (R-SSC-5628897); (R-SSC-611105); (R-SSC-9707564); (R-SSC-9864848)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "8396926", "class_list": "", "function": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1XQT3;Q9TRE9", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045277 respiratory chain complex IV", "go_biological_process": "GO:0006123 mitochondrial electron transport, cytochrome c to oxygen", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1W0Y2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q27HK4-1", "uniprot_id": [ { "id": "MTX1_PIG", "url": "https://www.uniprot.org/uniprot/Q27HK4", "type": "external" } ], "mass": 35769.0, "length": 317, "protein_name": "Metaxin-1", "gene_name": "MTX1", "organism": "Pig", "refseq_name": "metaxin-1", "refseq_ac": [ { "id": "NP_001034839", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034839", "type": "external" } ], "gene_names_uniprotkb": "MTX1", "gene_names_refseq": "MTX1; Metaxin-1", "protein_names_uniprotkb": "Metaxin-1; Mitochondrial outer membrane import complex protein 1", "protein_names_refseq": "metaxin-1; mitochondrial outer membrane import complex protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:664654); (R-SSC-9013404)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8QW42", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0001401 SAM complex", "go_biological_process": "GO:0045040 protein insertion into mitochondrial outer membrane;GO:0015031 protein transport;GO:0070096 mitochondrial outer membrane translocase complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q27HK4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q28920-1", "uniprot_id": [ { "id": "SPMI_PIG", "url": "https://www.uniprot.org/uniprot/Q28920", "type": "external" } ], "mass": 15196.0, "length": 137, "protein_name": "Seminal plasma sperm motility inhibitor", "gene_name": "SPMI", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SPMI", "gene_names_refseq": "", "protein_names_uniprotkb": "Seminal plasma sperm motility inhibitor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "7635190", "class_list": "", "function": "Inhibitor of sperm motility., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007338 single fertilization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q28920-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q28970-1", "uniprot_id": [ { "id": "MYO7A_PIG", "url": "https://www.uniprot.org/uniprot/Q28970", "type": "external" } ], "mass": 64634.0, "length": 566, "protein_name": "Unconventional myosin-VIIa", "gene_name": "MYO7A", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "MYO7A", "gene_names_refseq": "", "protein_names_uniprotkb": "Unconventional myosin-VIIa", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "7568224;8022818", "class_list": "", "function": "Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles. Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q29064", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005938 cell cortex;GO:0015629 actin cytoskeleton;GO:0016020 membrane;GO:0045202 synapse", "go_biological_process": "GO:0042490 mechanoreceptor differentiation;GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0030048 actin filament-based movement;GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q28970-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q28985-1", "uniprot_id": [ { "id": "IBP5_PIG", "url": "https://www.uniprot.org/uniprot/Q28985", "type": "external" } ], "mass": 30337.0, "length": 271, "protein_name": "Insulin-like growth factor-binding protein 5", "gene_name": "IGFBP5", "organism": "Pig", "refseq_name": "insulin-like growth factor-binding protein 5 precursor", "refseq_ac": [ { "id": "NP_999264", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999264", "type": "external" } ], "gene_names_uniprotkb": "IGFBP5", "gene_names_refseq": "IGFBP5", "protein_names_uniprotkb": "Insulin-like growth factor-binding protein 5; IBP-5; IGF-binding protein 5; IGFBP-5", "protein_names_refseq": "IBP-5; IGF-binding protein 5; IGFBP-5; insulin-like growth factor-binding protein 5 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397182); (R-SSC-381426); (R-SSC-8957275)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "15001525;19941052;24668639;8573141", "class_list": "", "function": "Endogenous IGFBP-5 or transiently expressed IGFBP-5-EGFP is localized in the nuclei of VSMCs. It possesses transcription-regulatory activity that is IGF independent., [RefSeq, PubMed]; IGFBP-5 gene is associated with the variation in meat quality, especially in pH value together with other QTLs on chromosome 15., [RefSeq, PubMed]; Multifunctional protein that plays a critical role in regulating the availability of IGFs to their receptors and thereby regulates IGF-mediated cellular processes including proliferation, differentiation, and apoptosis in a cell-type specific manner. Increases the cell proliferation of osteoblasts, intestinal smooth muscle cells and neuroblastoma cells (By similarity). Enhances adhesion and survival of epithelial cells but decreases adhesion of mesenchymal cells (By similarity). Once secreted, acts as a major mediator of mTORC1-dependent feedback inhibition of IGF1 signaling (By similarity). Also plays a role in the induction of extracellular matrix (ECM) production and deposition independently of its nuclear translocation and binding to IGFs. Acts itself as a growth factor that can act independently of IGFs to regulate bone formation. Acts as a ligand for the ROR1 receptor which triggers formation of ROR1/HER2 heterodimer to enhance CREB oncogenic signaling (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; The present study revealed SNPs in exon 1 of IGFBP-5 gene in the Tibet Mini-pig, possibly providing more understanding of the mechanism of miniaturization Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001968 fibronectin binding;GO:0031994 insulin-like growth factor I binding;GO:0031995 insulin-like growth factor II binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0060416 response to growth hormone;GO:0043567 regulation of insulin-like growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q28985-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q28992-1", "uniprot_id": [ { "id": "VIPR1_PIG", "url": "https://www.uniprot.org/uniprot/Q28992", "type": "external" } ], "mass": 51479.0, "length": 458, "protein_name": "Vasoactive intestinal polypeptide receptor 1", "gene_name": "VIPR1", "organism": "Pig", "refseq_name": "vasoactive intestinal polypeptide receptor 1 precursor", "refseq_ac": [ { "id": "NP_999201", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999201", "type": "external" } ], "gene_names_uniprotkb": "VIPR1", "gene_names_refseq": "PACAP-R-2; PACAP-R2; VIP-R-1; VIPR1; VPAC1", "protein_names_uniprotkb": "Vasoactive intestinal polypeptide receptor 1; PACAP type II receptor; PACAP-R-2; PACAP-R2; Pituitary adenylate cyclase-activating polypeptide type II receptor; VIP-R-1", "protein_names_refseq": "PACAP type II receptor; pituitary adenylate cyclase-activating polypeptide type II receptor; vasoactive intestinal polypeptide receptor 1 precursor; vasoactive intestinal polypeptide receptor 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100155402)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "25928928;33388613", "class_list": "", "function": "Alterations in the relative abundance of the vasoactive intestinal peptide receptors (VPAC1 and VPAC2) and functions in uterine contractility during inflammation., [RefSeq, PubMed]; G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP). Binds VIP and both PACAP27 and PACAP38 bioactive peptides with the following order of ligand affinity VIP = PACAP27 > PACAP38. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway., [UniProtKB, UniProtKB]; The study confirmed the presence of VPAC1 receptor in the tissues of the porcine female reproductive tract what clearly shows the possibility of influence of vasoactive intestinal polypeptide on the porcine ovary, oviduct and uterus., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017046 peptide hormone binding;GO:0008528 G protein-coupled peptide receptor activity;GO:0004999 vasoactive intestinal polypeptide receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q28992-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q28996-1", "uniprot_id": [ { "id": "STAR_PIG", "url": "https://www.uniprot.org/uniprot/Q28996", "type": "external" } ], "mass": 31932.0, "length": 285, "protein_name": "Steroidogenic acute regulatory protein, mitochondrial", "gene_name": "STAR", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "STAR", "gene_names_refseq": "", "protein_names_uniprotkb": "Steroidogenic acute regulatory protein, mitochondrial; START domain-containing protein 1; StARD1; StAR", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "8977433;9048613", "class_list": "", "function": "Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q53Z33;Q95259", "ec_number_list": [], "go_molecular_function": "GO:0015485 cholesterol binding;GO:0120020 cholesterol transfer activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0032367 intracellular cholesterol transport;GO:0006694 steroid biosynthetic process;GO:0006704 glucocorticoid biosynthetic process;GO:0050810 regulation of steroid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q28996-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29003-1", "uniprot_id": [ { "id": "5HT1E_PIG", "url": "https://www.uniprot.org/uniprot/Q29003", "type": "external" } ], "mass": 17116.0, "length": 149, "protein_name": "5-hydroxytryptamine receptor 1E", "gene_name": "HTR1E", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "HTR1E", "gene_names_refseq": "", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 1E; 5-HT-1E; 5-HT1E; Serotonin receptor 1E", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "7656980", "class_list": "", "function": "G protein-coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. HTR1E is coupled to G(i)/G(o) G alpha proteins and mediates inhibitory neurotransmission by inhibiting adenylate cyclase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004993 G protein-coupled serotonin receptor activity;GO:0030594 neurotransmitter receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0045202 synapse", "go_biological_process": "GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission;GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29003-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29005-1", "uniprot_id": [ { "id": "5HT2B_PIG", "url": "https://www.uniprot.org/uniprot/Q29005", "type": "external" } ], "mass": 6725.0, "length": 60, "protein_name": "5-hydroxytryptamine receptor 2B", "gene_name": "HTR2B", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "HTR2B", "gene_names_refseq": "", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 2B; 5-HT-2B; 5-HT2B; Serotonin receptor 2B", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "7656980", "class_list": "", "function": "G protein-coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR2B is coupled to G(q)/G(11) G alpha proteins and activates phospholipase C-beta, releasing diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) second messengers that modulate the activity of phosphatidylinositol 3-kinase and promote the release of Ca(2+) ions from intracellular stores, respectively. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways (By similarity). Plays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects neural activity. May play a role in the perception of pain (By similarity). Plays a role in the regulation of behavior, including impulsive behavior (By similarity). Required for normal proliferation of embryonic cardiac myocytes and normal heart development. Protects cardiomyocytes against apoptosis. Plays a role in the adaptation of pulmonary arteries to chronic hypoxia. Plays a role in vasoconstriction. Required for normal osteoblast function and proliferation, and for maintaining normal bone density. Required for normal proliferation of the interstitial cells of Cajal in the intestine (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse;GO:0043005 neuron projection", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29005-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29006-1", "uniprot_id": [ { "id": "5HT4R_PIG", "url": "https://www.uniprot.org/uniprot/Q29006", "type": "external" } ], "mass": 15622.0, "length": 137, "protein_name": "5-hydroxytryptamine receptor 4", "gene_name": "HTR4", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "HTR4", "gene_names_refseq": "", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 4; 5-HT-4; 5-HT4; Serotonin receptor 4", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "7656980", "class_list": "", "function": "G protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR4 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004993 G protein-coupled serotonin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse;GO:0010008 endosome membrane", "go_biological_process": "GO:0007268 chemical synaptic transmission;GO:0032098 regulation of appetite;GO:0007192 adenylate cyclase-activating serotonin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29006-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29010-1", "uniprot_id": [ { "id": "EDNRA_PIG", "url": "https://www.uniprot.org/uniprot/Q29010", "type": "external" } ], "mass": 48694.0, "length": 427, "protein_name": "Endothelin-1 receptor", "gene_name": "EDNRA", "organism": "Pig", "refseq_name": "endothelin-1 receptor precursor", "refseq_ac": [ { "id": "NP_999394", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999394", "type": "external" } ], "gene_names_uniprotkb": "EDNRA", "gene_names_refseq": "EDNRA", "protein_names_uniprotkb": "Endothelin-1 receptor; ET-AR; ET-A; Endothelin receptor type A", "protein_names_refseq": "ET-AR; ET-A; endothelin A receptor; endothelin receptor subtype A; endothelin-1 receptor precursor; endothelin-1 receptor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397457)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12911546;15240868;15838252;21726419;21760895;22908974;24414253;26211713;8564193", "class_list": "", "function": "Blockade improves renal hemodynamic and function in hypercholesterolemia(HC), and decreases oxidative stress, and renal vascular and tubulointerstitial inflammation and fibrosis. Role for endothelin system in renal injury in HC and atherosclerosis., [RefSeq, PubMed]; Blocking ET(A) and ET(B) receptors partially protects sinusoidal circulation and tissue oxygenation against stress induced by high intra-abdominal pressure (IAP)., [RefSeq, PubMed]; Dual endothelin receptor blockade with tezosentan attenuates hypoxia-induced pulmonary vasoconstriction in porcine model., [RefSeq, PubMed]; Endothelin-A receptor antagonist alters the expression of vasoactive genes and proinflammatory cytokines during hepatic ischemic/reperfusion., [RefSeq, PubMed]; PDE5 inhibition and increase in cGMP produce pulmonary vasodilation that is mediated in part through inhibition of the ET pathway, thereby precluding an additional vasodilator effect of ETA/ETB receptor blockade in the presence of PDE5 inhibition., [RefSeq, PubMed]; Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3 (By similarity)., [UniProtKB]; Results suggest that endothelin A and B receptor protein and mRNA expression is developmentally regulated in the postnatal swine mesenteric artery., [RefSeq, PubMed]; Sub-vasomotor concentration of ET-1 leads to vascular dysfunction by impairing endothelium-dependent NO-mediated dilation via p38 kinase-mediated production of superoxide from NADPH oxidase following ETA receptor activation, [RefSeq, PubMed]; These results suggest that endothelin released during endotoxemia acts via endothelin A receptors to impair renal medullary blood flow causing ischemia., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004962 endothelin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0048484 enteric nervous system development;GO:0086100 endothelin receptor signaling pathway;GO:0008217 regulation of blood pressure;GO:0042310 vasoconstriction;GO:0048066 developmental pigmentation", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q29010-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29029-1", "uniprot_id": [ { "id": "MPIP3_PIG", "url": "https://www.uniprot.org/uniprot/Q29029", "type": "external" } ], "mass": 56639.0, "length": 502, "protein_name": "M-phase inducer phosphatase 3", "gene_name": "CDC25C", "organism": "Pig", "refseq_name": "M-phase inducer phosphatase 3 isoform 1", "refseq_ac": [ { "id": "NP_001116567", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116567", "type": "external" } ], "gene_names_uniprotkb": "CDC25C", "gene_names_refseq": "CDC25C", "protein_names_uniprotkb": "M-phase inducer phosphatase 3; 3.1.3.48; Dual specificity phosphatase Cdc25C", "protein_names_refseq": "M-phase inducer phosphatase 3 isoform 1; M-phase inducer phosphatase 3; cell division cycle 25 homolog C; dual specificity phosphatase Cdc25C", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144474); (R-SSC-156711); (R-SSC-176187); (R-SSC-5625740); (R-SSC-6804115); (R-SSC-69273); (R-SSC-75035)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "7601801", "class_list": "", "function": "Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 16, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0010971 positive regulation of G2/M transition of mitotic cell cycle;GO:0051301 cell division;GO:0000086 G2/M transition of mitotic cell cycle;GO:0110032 positive regulation of G2/MI transition of meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29029-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29052-1", "uniprot_id": [ { "id": "ITIH1_PIG", "url": "https://www.uniprot.org/uniprot/Q29052", "type": "external" } ], "mass": 100395.0, "length": 902, "protein_name": "Inter-alpha-trypsin inhibitor heavy chain H1", "gene_name": "ITIH1", "organism": "Pig", "refseq_name": "inter-alpha-trypsin inhibitor heavy chain H1 precursor", "refseq_ac": [ { "id": "NP_999089", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999089", "type": "external" } ], "gene_names_uniprotkb": "ITIH1", "gene_names_refseq": "ITIH1", "protein_names_uniprotkb": "Inter-alpha-trypsin inhibitor heavy chain H1; ITI heavy chain H1; ITI-HC1; Inter-alpha-inhibitor heavy chain 1", "protein_names_refseq": "ITI heavy chain H1; ITI-HC1; inter-alpha (globulin) inhibitor H1; inter-alpha-inhibitor heavy chain 1; inter-alpha-trypsin inhibitor heavy chain H1 precursor; inter-alpha-trypsin inhibitor heavy chain H1", "tax_id": 9823, "disease": "", "pathway": " (ssc:396963)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes., [UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 3, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 1, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "O02669", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006953 acute-phase response;GO:0030212 hyaluronan metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29052-1", "record_type": "protein", "filter_code": "0000000.0000001.010000.000000000000010000.0000000011011.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29053-1", "uniprot_id": [ { "id": "IL12A_PIG", "url": "https://www.uniprot.org/uniprot/Q29053", "type": "external" } ], "mass": 24945.0, "length": 222, "protein_name": "Interleukin-12 subunit alpha", "gene_name": "IL12A", "organism": "Pig", "refseq_name": "interleukin-12 subunit alpha isoform 1", "refseq_ac": [ { "id": "NP_999158", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999158", "type": "external" } ], "gene_names_uniprotkb": "IL12A", "gene_names_refseq": "IL12A", "protein_names_uniprotkb": "Interleukin-12 subunit alpha; CLMF p35; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL-12 subunit p35; IL-12A", "protein_names_refseq": "CLMF p35; IL-12 subunit p35; IL-12A; Interleukin-12 subunit alpha; cytotoxic lymphocyte maturation factor 35 kDa subunit; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35); interleukin-12 p35 subunit; interleukin-12 subunit alpha isoform 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397053)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "9239844", "class_list": "", "function": "Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity. Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits. Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2. In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes (By similarity). As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and also functions as an immune-suppressive cytokine (By similarity). Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers. Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005143 interleukin-12 receptor binding;GO:0005125 cytokine activity;GO:0008083 growth factor activity", "go_cellular_component": "GO:0043514 interleukin-12 complex", "go_biological_process": "GO:0032946 positive regulation of mononuclear cell proliferation;GO:0006955 immune response;GO:0035722 interleukin-12-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29053-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29056-1", "uniprot_id": [ { "id": "IL1RA_PIG", "url": "https://www.uniprot.org/uniprot/Q29056", "type": "external" } ], "mass": 20093.0, "length": 177, "protein_name": "Interleukin-1 receptor antagonist protein", "gene_name": "IL1RN", "organism": "Pig", "refseq_name": "interleukin-1 receptor antagonist protein precursor", "refseq_ac": [ { "id": "NP_999427", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999427", "type": "external" } ], "gene_names_uniprotkb": "IL1RN; IRAP1", "gene_names_refseq": "IL1RN; IRAP1", "protein_names_uniprotkb": "Interleukin-1 receptor antagonist protein; IL-1RN; IL-1ra; IL1 inhibitor; IRAP", "protein_names_refseq": "IL-1RN; IL-1ra; IL1 inhibitor; IRAP; interleukin-1 receptor antagonist protein precursor; interleukin-1 receptor antagonist protein", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "27902420", "class_list": "", "function": "Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens., [UniProtKB, UniProtKB]; This study identified IL-1Ra as an early immunomodulatory mediator that could be involved in the immunopathogenesis of porcine reproductive and respiratory syndrome virus infections., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005152 interleukin-1 receptor antagonist activity;GO:0005125 cytokine activity;GO:0005149 interleukin-1 receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:2000660 negative regulation of interleukin-1-mediated signaling pathway;GO:0006954 inflammatory response;GO:0006955 immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29056-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29058-1", "uniprot_id": [ { "id": "LEG4_PIG", "url": "https://www.uniprot.org/uniprot/Q29058", "type": "external" } ], "mass": 35852.0, "length": 323, "protein_name": "Galectin-4", "gene_name": "LGALS4", "organism": "Pig", "refseq_name": "galectin-4", "refseq_ac": [ { "id": "NP_999146", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999146", "type": "external" } ], "gene_names_uniprotkb": "LGALS4", "gene_names_refseq": "L36LBP; LGALS4", "protein_names_uniprotkb": "Galectin-4; Gal-4; L-36 lactose-binding protein; L36LBP; Lactose-binding lectin 4", "protein_names_refseq": "L-36 lactose binding protein; gal-4; galectin-4; lactose-binding lectin 4; lectin, galactoside-binding, soluble, 4 (galectin 4)", "tax_id": 9823, "disease": "", "pathway": " (ssc:397041)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "7989350;8672129", "class_list": "", "function": "Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q29296", "ec_number_list": [], "go_molecular_function": "GO:0030246 carbohydrate binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q29058-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29077-1", "uniprot_id": [ { "id": "ODFP1_PIG", "url": "https://www.uniprot.org/uniprot/Q29077", "type": "external" } ], "mass": 29526.0, "length": 262, "protein_name": "Outer dense fiber protein 1", "gene_name": "ODF1", "organism": "Pig", "refseq_name": "outer dense fiber protein 1", "refseq_ac": [ { "id": "NP_999420", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999420", "type": "external" } ], "gene_names_uniprotkb": "ODF1; ODFP", "gene_names_refseq": "ODF1; ODFP", "protein_names_uniprotkb": "Outer dense fiber protein 1", "protein_names_refseq": "outer dense fiber protein 1; outer dense fibers", "tax_id": 9823, "disease": "", "pathway": " (ssc:397489)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "7576240", "class_list": "", "function": "Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0001520 outer dense fiber;GO:0005813 centrosome;GO:0036126 sperm flagellum;GO:0002177 manchette", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29077-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29078-1", "uniprot_id": [ { "id": "PAG1_PIG", "url": "https://www.uniprot.org/uniprot/Q29078", "type": "external" } ], "mass": 43533.0, "length": 389, "protein_name": "Pregnancy-associated glycoprotein 1", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Pregnancy-associated glycoprotein 1; 3.4.23.-; PAG 1; PAG1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "7669851", "class_list": "", "function": "Appears to be proteolytically inactive., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004190 aspartic-type endopeptidase activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29078-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29079-1", "uniprot_id": [ { "id": "PAG2_PIG", "url": "https://www.uniprot.org/uniprot/Q29079", "type": "external" } ], "mass": 47132.0, "length": 420, "protein_name": "Pregnancy-associated glycoprotein 2", "gene_name": "PAG2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PAG2", "gene_names_refseq": "", "protein_names_uniprotkb": "Pregnancy-associated glycoprotein 2; 3.4.23.-; PAG 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "11553911;7669851", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q29017", "ec_number_list": [], "go_molecular_function": "GO:0004190 aspartic-type endopeptidase activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q29079-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29084-1", "uniprot_id": [ { "id": "Q29084_PIG", "url": "https://www.uniprot.org/uniprot/Q29084", "type": "external" } ], "mass": 20621.0, "length": 179, "protein_name": "Uncharacterized protein", "gene_name": "LOC100155760", "organism": "Pig", "refseq_name": "interferon omega 1 precursor", "refseq_ac": [ { "id": "NP_001123710", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001123710", "type": "external" } ], "gene_names_uniprotkb": "LOC100155760", "gene_names_refseq": "LOC100155760", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "IFN-omega-1; PoIFN-alpha II-4; interferon omega 1 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100155760)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0005132 type I interferon receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0002312 B cell activation involved in immune response;GO:0051607 defense response to virus;GO:0060337 type I interferon-mediated signaling pathway;GO:0002250 adaptive immune response;GO:0043330 response to exogenous dsRNA", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29084-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29098-1", "uniprot_id": [ { "id": "Q29098_PIG", "url": "https://www.uniprot.org/uniprot/Q29098", "type": "external" } ], "mass": 21535.0, "length": 190, "protein_name": "Interferon omega 7", "gene_name": "IFN-OMEGA-7", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IFN-OMEGA-7", "gene_names_refseq": "", "protein_names_uniprotkb": "Interferon omega 7", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "I3L756", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0005132 type I interferon receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0002312 B cell activation involved in immune response;GO:0051607 defense response to virus;GO:0060337 type I interferon-mediated signaling pathway;GO:0002250 adaptive immune response;GO:0043330 response to exogenous dsRNA", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29098-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29099-1", "uniprot_id": [ { "id": "PTBP1_PIG", "url": "https://www.uniprot.org/uniprot/Q29099", "type": "external" } ], "mass": 59694.0, "length": 557, "protein_name": "Polypyrimidine tract-binding protein 1", "gene_name": "PTBP1", "organism": "Pig", "refseq_name": "polypyrimidine tract-binding protein 1", "refseq_ac": [ { "id": "NP_999396", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999396", "type": "external" } ], "gene_names_uniprotkb": "PTBP1; PTB", "gene_names_refseq": "PTBP1; PTB", "protein_names_uniprotkb": "Polypyrimidine tract-binding protein 1; Heterogeneous nuclear ribonucleoprotein I; PTB; hnRNP I", "protein_names_refseq": "heterogeneous nuclear ribonucleoprotein I; hnRNP I; polypyrimidine tract-binding protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397461); (R-SSC-6803529); (R-SSC-72163); (R-SSC-72203); (R-SSC-9770562)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "8654585", "class_list": "", "function": "Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. Binds to polypyrimidine-rich controlling element (PCE) of CFTR and promotes exon skipping of CFTR exon 9, thereby antagonizing TIA1 and its role in exon inclusion of CFTR exon 9. Plays a role in the splicing of pyruvate kinase PKM by binding repressively to a polypyrimidine tract flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1VPV8", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0048025 negative regulation of mRNA splicing, via spliceosome;GO:0045595 regulation of cell differentiation;GO:0043484 regulation of RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29099-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29100-1", "uniprot_id": [ { "id": "UPTI_PIG", "url": "https://www.uniprot.org/uniprot/Q29100", "type": "external" } ], "mass": 13109.0, "length": 122, "protein_name": "Uterine plasmin/trypsin inhibitor", "gene_name": "", "organism": "Pig", "refseq_name": "uterine plasmin/trypsin inhibitor precursor", "refseq_ac": [ { "id": "NP_999036", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999036", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "UPTI", "protein_names_uniprotkb": "Uterine plasmin/trypsin inhibitor; UPTI", "protein_names_refseq": "uterine plasmin/trypsin inhibitor precursor; uterine plasmin/trypsin inhibitor", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "7929061", "class_list": "", "function": "Inhibitor of plasmin and trypsin. Also has a weak affinity for chymotrypsin. Could serve to neutralize the activities of one or more serine proteinases generated by the proliferating trophoblast during the formation of the noninvasive placenta., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29100-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29106-1", "uniprot_id": [ { "id": "RSCA1_PIG", "url": "https://www.uniprot.org/uniprot/Q29106", "type": "external" } ], "mass": 66832.0, "length": 623, "protein_name": "Regulatory solute carrier protein family 1 member 1", "gene_name": "RSC1A1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "RSC1A1", "gene_names_refseq": "", "protein_names_uniprotkb": "Regulatory solute carrier protein family 1 member 1; Transporter regulator RS1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:396699)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11018680;11562363;16788147;8227068", "class_list": "", "function": "Mediates transcriptional and post-transcriptional regulation of SLC5A1. Inhibits a dynamin and PKC-dependent exocytotic pathway of SLC5A1. Also involved in transcriptional regulation of SLC22A2. Exhibits glucose-dependent, short-term inhibition of SLC5A1 and SLC22A2 by inhibiting the release of vesicles from the trans-Golgi network (By similarity)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q29106-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29108-1", "uniprot_id": [ { "id": "ZPBP1_PIG", "url": "https://www.uniprot.org/uniprot/Q29108", "type": "external" } ], "mass": 39624.0, "length": 350, "protein_name": "Zona pellucida-binding protein 1", "gene_name": "ZPBP", "organism": "Pig", "refseq_name": "zona pellucida-binding protein 1 precursor", "refseq_ac": [ { "id": "NP_999271", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999271", "type": "external" } ], "gene_names_uniprotkb": "ZPBP; ZPBP1", "gene_names_refseq": "ZPBP", "protein_names_uniprotkb": "Zona pellucida-binding protein 1; Inner acrosomal membrane IAM38; Sp38", "protein_names_refseq": "Zona-pellucida-binding protein (sp38); inner acrosomal membrane IAM38; zona pellucida-binding protein 1 precursor; zona pellucida-binding protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397194)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "7729589", "class_list": "", "function": "Plays a role in acrosome compaction and sperm morphogenesis. Is implicated in sperm-oocyte interaction during fertilization., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0001669 acrosomal vesicle;GO:0002080 acrosomal membrane;GO:0002199 zona pellucida receptor complex", "go_biological_process": "GO:0007339 binding of sperm to zona pellucida;GO:0001675 acrosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29108-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29115-1", "uniprot_id": [ { "id": "Q29115_PIG", "url": "https://www.uniprot.org/uniprot/Q29115", "type": "external" } ], "mass": 19863.0, "length": 170, "protein_name": "Interferon-delta-1", "gene_name": "IFN-DELTA-2", "organism": "Pig", "refseq_name": "interferon-delta-2 precursor", "refseq_ac": [ { "id": "NP_001159793", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001159793", "type": "external" } ], "gene_names_uniprotkb": "IFN-DELTA-2", "gene_names_refseq": "IFN-DELTA-2", "protein_names_uniprotkb": "Interferon-delta-1", "protein_names_refseq": "IFN-delta-1; interferon-delta-1; interferon-delta-2 precursor; short type I interferon; spI IFN", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0005132 type I interferon receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0002312 B cell activation involved in immune response;GO:0051607 defense response to virus;GO:0060337 type I interferon-mediated signaling pathway;GO:0002250 adaptive immune response;GO:0043330 response to exogenous dsRNA", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29115-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29125-1", "uniprot_id": [ { "id": "ELAF_PIG", "url": "https://www.uniprot.org/uniprot/Q29125", "type": "external" } ], "mass": 17923.0, "length": 167, "protein_name": "Elafin", "gene_name": "", "organism": "Pig", "refseq_name": "elafin precursor", "refseq_ac": [ { "id": "NP_001116687", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116687", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "PI3; WAP-1", "protein_names_uniprotkb": "Elafin; Protein WAP-1", "protein_names_refseq": "elafin precursor; elafin; protein WAP-1; trappin 8", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-6803157); (R-SSC-6809371)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "8636131", "class_list": "", "function": "Neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0019731 antibacterial humoral response;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29125-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29187-1", "uniprot_id": [ { "id": "RL4_PIG", "url": "https://www.uniprot.org/uniprot/Q29187", "type": "external" } ], "mass": 11109.0, "length": 101, "protein_name": "Large ribosomal subunit protein uL4", "gene_name": "RPL4", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "RPL4; RPL1", "gene_names_refseq": "", "protein_names_uniprotkb": "Large ribosomal subunit protein uL4; 60S ribosomal protein L1; 60S ribosomal protein L4", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29187-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29197-1", "uniprot_id": [ { "id": "RS9_PIG", "url": "https://www.uniprot.org/uniprot/Q29197", "type": "external" } ], "mass": 15520.0, "length": 130, "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "RPS9", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "RPS9", "gene_names_refseq": "", "protein_names_uniprotkb": "Small ribosomal subunit protein uS4; 40S ribosomal protein S9", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Component of the small ribosomal subunit. 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The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6QAQ2", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0015935 small ribosomal subunit;GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane;GO:0032040 small-subunit processome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29201-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29238-1", "uniprot_id": [ { "id": "CLIC1_PIG", "url": "https://www.uniprot.org/uniprot/Q29238", "type": "external" } ], "mass": 12184.0, "length": 110, "protein_name": "Chloride intracellular channel protein 1", "gene_name": "CLIC1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CLIC1", "gene_names_refseq": "", "protein_names_uniprotkb": "Chloride intracellular channel protein 1; 1.8.-.-; 1.8.5.1; Glutaredoxin-like oxidoreductase CLIC1; Glutathione-dependent dehydroascorbate reductase CLIC1; Nuclear chloride ion channel 27", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Reduces selenite and dehydroascorbate and may act as an antioxidant during oxidative stress response (By similarity). Can insert into membranes and form voltage-dependent multi-ion conductive channels. Membrane insertion seems to be redox-regulated and may occur only under oxidizing conditions. Involved in regulation of the cell cycle (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005254 chloride channel activity;GO:0045174 glutathione dehydrogenase (ascorbate) activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0031965 nuclear membrane;GO:0034707 chloride channel complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29238-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29259-1", "uniprot_id": [ { "id": "NDUB6_PIG", "url": "https://www.uniprot.org/uniprot/Q29259", "type": "external" } ], "mass": 15390.0, "length": 128, "protein_name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6", "gene_name": "NDUFB6", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "NDUFB6", "gene_names_refseq": "", "protein_names_uniprotkb": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6; CI-B17; Complex I-B17; NADH-ubiquinone oxidoreductase B17 subunit", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045271 respiratory chain complex I", "go_biological_process": "GO:0006120 mitochondrial electron transport, NADH to ubiquinone;GO:0042775 mitochondrial ATP synthesis coupled electron transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29259-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29277-1", "uniprot_id": [ { "id": "PPR1B_PIG", "url": "https://www.uniprot.org/uniprot/Q29277", "type": "external" } ], "mass": 15802.0, "length": 137, "protein_name": "Protein phosphatase 1 regulatory subunit 1B", "gene_name": "PPP1R1B", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PPP1R1B", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein phosphatase 1 regulatory subunit 1B; DARPP-32; Dopamine- and cAMP-regulated neuronal phosphoprotein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Inhibitor of protein-phosphatase 1., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004864 protein phosphatase inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29277-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29288-1", "uniprot_id": [ { "id": "CCL5_PIG", "url": "https://www.uniprot.org/uniprot/Q29288", "type": "external" } ], "mass": 5937.0, "length": 50, "protein_name": "C-C motif chemokine 5", "gene_name": "CCL5", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CCL5; SCYA5", "gene_names_refseq": "", "protein_names_uniprotkb": "C-C motif chemokine 5; SIS-delta; Small-inducible cytokine A5; T-cell-specific protein RANTES", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008009 chemokine activity;GO:0048020 CCR chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006954 inflammatory response;GO:0007186 G protein-coupled receptor signaling pathway;GO:0030335 positive regulation of cell migration;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098 chemokine-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29288-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29297-1", "uniprot_id": [ { "id": "SCIN_PIG", "url": "https://www.uniprot.org/uniprot/Q29297", "type": "external" } ], "mass": 13971.0, "length": 125, "protein_name": "Scinderin", "gene_name": "SCIN", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SCIN", "gene_names_refseq": "", "protein_names_uniprotkb": "Scinderin; Adseverin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Ca(2+)-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Severing activity is inhibited by phosphatidylinositol 4,5-bis-phosphate (PIP2) (By similarity). Required for megakaryocyte differentiation, maturation, polyploidization and apoptosis with the release of platelet-like particles (By similarity). Plays a role in osteoclastogenesis (OCG) and actin cytoskeletal organization in osteoclasts (By similarity). Regulates chondrocyte proliferation and differentiation (By similarity). Inhibits cell proliferation and tumorigenesis. Signaling is mediated by MAPK, p38 and JNK pathways (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0002102 podosome", "go_biological_process": "GO:0032330 regulation of chondrocyte differentiation;GO:0051693 actin filament capping", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29297-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29303-1", "uniprot_id": [ { "id": "RS14_PIG", "url": "https://www.uniprot.org/uniprot/Q29303", "type": "external" } ], "mass": 8538.0, "length": 79, "protein_name": "Small ribosomal subunit protein uS11", "gene_name": "RPS14", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "RPS14", "gene_names_refseq": "", "protein_names_uniprotkb": "Small ribosomal subunit protein uS11; 40S ribosomal protein S14", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0032040 small-subunit processome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29303-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29308-1", "uniprot_id": [ { "id": "RS19_PIG", "url": "https://www.uniprot.org/uniprot/Q29308", "type": "external" } ], "mass": 15096.0, "length": 136, "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "RPS19", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "RPS19", "gene_names_refseq": "", "protein_names_uniprotkb": "Small ribosomal subunit protein eS19; 40S ribosomal protein S19", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Required for pre-rRNA processing and maturation of 40S ribosomal subunits. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0032040 small-subunit processome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0042274 ribosomal small subunit biogenesis;GO:0000028 ribosomal small subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29308-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29350-1", "uniprot_id": [ { "id": "U2AF1_PIG", "url": "https://www.uniprot.org/uniprot/Q29350", "type": "external" } ], "mass": 9416.0, "length": 82, "protein_name": "Splicing factor U2AF 35 kDa subunit", "gene_name": "U2AF1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "U2AF1", "gene_names_refseq": "", "protein_names_uniprotkb": "Splicing factor U2AF 35 kDa subunit; U2 auxiliary factor 35 kDa subunit; U2 snRNP auxiliary factor small subunit", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0016607 nuclear speck;GO:0005681 spliceosomal complex;GO:0089701 U2AF complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29350-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29380-1", "uniprot_id": [ { "id": "VDAC3_PIG", "url": "https://www.uniprot.org/uniprot/Q29380", "type": "external" } ], "mass": 30578.0, "length": 283, "protein_name": "Non-selective voltage-gated ion channel VDAC3", "gene_name": "VDAC3", "organism": "Pig", "refseq_name": "non-selective voltage-gated ion channel VDAC3", "refseq_ac": [ { "id": "NP_999529", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999529", "type": "external" } ], "gene_names_uniprotkb": "VDAC3", "gene_names_refseq": "VDAC1P5; VDAC3; VDAC5P", "protein_names_uniprotkb": "Non-selective voltage-gated ion channel VDAC3; Outer mitochondrial membrane protein porin 3; VDAC-3", "protein_names_refseq": "VDAC-3; non-selective voltage-gated ion channel VDAC3; outer mitochondrial membrane protein porin 3; voltage-dependent anion channel 1 pseudogene 5; voltage-dependent anion channel 5, pseudogene; voltage-dependent anion-selective channel protein 3", "tax_id": 9823, "disease": "", "pathway": " (ssc:397651)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Non-selective voltage-gated ion channel that mediates the transport of anions and cations through the mitochondrion outer membrane and plasma membrane. Forms a high-conducting channel with a stable open state and a voltage-induced closure with a mild preference for anions over cations (By similarity). Involved in male fertility and sperm mitochondrial sheath formation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9MZ14", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0015288 porin activity;GO:0008308 voltage-gated monoatomic anion channel activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0016020 membrane;GO:0046930 pore complex", "go_biological_process": "GO:0007283 spermatogenesis;GO:0120317 sperm mitochondrial sheath assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29380-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29384-1", "uniprot_id": [ { "id": "PSB4_PIG", "url": "https://www.uniprot.org/uniprot/Q29384", "type": "external" } ], "mass": 16928.0, "length": 154, "protein_name": "Proteasome subunit beta type-4", "gene_name": "PSMB4", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PSMB4", "gene_names_refseq": "", "protein_names_uniprotkb": "Proteasome subunit beta type-4; Macropain beta chain; Multicatalytic endopeptidase complex beta chain; Proteasome beta chain; Proteasome chain 3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0019774 proteasome core complex, beta-subunit complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005839 proteasome core complex", "go_biological_process": "GO:0051603 proteolysis involved in protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29384-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29387-1", "uniprot_id": [ { "id": "EF1G_PIG", "url": "https://www.uniprot.org/uniprot/Q29387", "type": "external" } ], "mass": 49624.0, "length": 432, "protein_name": "Elongation factor 1-gamma", "gene_name": "EEF1G", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "EEF1G", "gene_names_refseq": "", "protein_names_uniprotkb": "Elongation factor 1-gamma; EF-1-gamma; eEF-1B gamma", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Probably plays a role in anchoring the complex to other cellular components., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SPX8", "ec_number_list": [], "go_molecular_function": "GO:0003746 translation elongation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006414 translational elongation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29387-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29559-1", "uniprot_id": [ { "id": "CXA4_PIG", "url": "https://www.uniprot.org/uniprot/Q29559", "type": "external" } ], "mass": 15836.0, "length": 138, "protein_name": "Gap junction alpha-4 protein", "gene_name": "GJA4", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "GJA4", "gene_names_refseq": "", "protein_names_uniprotkb": "Gap junction alpha-4 protein; Connexin-37; Cx37", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8832399", "class_list": "", "function": "One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005922 connexin complex", "go_biological_process": "GO:0007154 cell communication", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29559-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29576-1", "uniprot_id": [ { "id": "PSB8_PIG", "url": "https://www.uniprot.org/uniprot/Q29576", "type": "external" } ], "mass": 11604.0, "length": 104, "protein_name": "Proteasome subunit beta type-8", "gene_name": "PSMB8", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PSMB8", "gene_names_refseq": "", "protein_names_uniprotkb": "Proteasome subunit beta type-8; 3.4.25.1; Macropain subunit C13; Multicatalytic endopeptidase complex subunit C13; Proteasome component C13; Proteasome subunit beta-5i", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. May participate in the generation of spliced peptides resulting from the ligation of two separate proteasomal cleavage products that are not contiguous in the parental protein (By similarity). Required for adipocyte differentiation (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004298 threonine-type endopeptidase activity", "go_cellular_component": "GO:0019774 proteasome core complex, beta-subunit complex;GO:1990111 spermatoproteasome complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005839 proteasome core complex", "go_biological_process": "GO:0045444 fat cell differentiation;GO:0051603 proteolysis involved in protein catabolic process;GO:0002376 immune system process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29576-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q29577-1", "uniprot_id": [ { "id": "KCRU_PIG", "url": "https://www.uniprot.org/uniprot/Q29577", "type": "external" } ], "mass": 46950.0, "length": 416, "protein_name": "Creatine kinase U-type, mitochondrial", "gene_name": "CKMT1", "organism": "Pig", "refseq_name": "creatine kinase U-type, mitochondrial", "refseq_ac": [ { "id": "NP_001302567", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001302567", "type": "external" } ], "gene_names_uniprotkb": "CKMT1", "gene_names_refseq": "CKMT1A; CKMT1B; CKMT1; Mia-CK; U-MtCK", "protein_names_uniprotkb": "Creatine kinase U-type, mitochondrial; 2.7.3.2; Acidic-type mitochondrial creatine kinase; Mia-CK; U-MtCK; Ubiquitous mitochondrial creatine kinase", "protein_names_refseq": "Acidic-type mitochondrial creatine kinase; Ubiquitous mitochondrial creatine kinase; creatine kinase U-type, mitochondrial; creatine kinase, mitochondrial 1B; mitochondrial creatine kinase 1B", "tax_id": 9823, "disease": "", "pathway": " (ssc:100519994)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B2ZF48", "ec_number_list": [], "go_molecular_function": "GO:0004111 creatine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0046314 phosphocreatine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29577-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q2EN81-1", "uniprot_id": [ { "id": "ATPO_PIG", "url": "https://www.uniprot.org/uniprot/Q2EN81", "type": "external" } ], "mass": 23370.0, "length": 213, "protein_name": "ATP synthase peripheral stalk subunit OSCP, mitochondrial", "gene_name": "ATP5PO", "organism": "Pig", "refseq_name": "ATP synthase peripheral stalk subunit OSCP, mitochondrial precursor", "refseq_ac": [ { "id": "NP_001038071", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038071", "type": "external" } ], "gene_names_uniprotkb": "ATP5PO; ATP5O", "gene_names_refseq": "ATP5O; ATP5PO; OSCP", "protein_names_uniprotkb": "ATP synthase peripheral stalk subunit OSCP, mitochondrial; ATP synthase subunit O; OSCP; Oligomycin sensitivity conferral protein", "protein_names_refseq": "ATP synthase peripheral stalk subunit OSCP, mitochondrial precursor; ATP synthase peripheral stalk subunit OSCP, mitochondrial; ATP synthase subunit O, mitochondrial; ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit; Oligomycin sensitivity conferral protein; mitochondrial ATP5O", "tax_id": 9823, "disease": "", "pathway": " (ssc:733678); (R-SSC-163210); (R-SSC-8949613); (R-SSC-9837999)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "7530007", "class_list": "", "function": "Subunit OSCP, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). Part of the complex F(0) domain (By similarity). Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1XQT0;Q9T2U6", "ec_number_list": [], "go_molecular_function": "GO:0046933 proton-transporting ATP synthase activity, rotational mechanism", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0042776 proton motive force-driven mitochondrial ATP synthesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2EN81-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q2EN82-1", "uniprot_id": [ { "id": "SELK_PIG", "url": "https://www.uniprot.org/uniprot/Q2EN82", "type": "external" } ], "mass": 10619.0, "length": 94, "protein_name": "Selenoprotein K", "gene_name": "SELENOK", "organism": "Pig", "refseq_name": "selenoprotein K", "refseq_ac": [ { "id": "NP_001038018", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038018", "type": "external" } ], "gene_names_uniprotkb": "SELENOK", "gene_names_refseq": "SELENOK; SELK", "protein_names_uniprotkb": "Selenoprotein K; SelK", "protein_names_refseq": "selenoprotein K", "tax_id": 9823, "disease": "", "pathway": " (ssc:733604)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for Ca(2+) flux in immune cells and plays a role in T-cell proliferation and in T-cell and neutrophil migration (By similarity). Involved in endoplasmic reticulum-associated degradation (ERAD) of soluble glycosylated proteins (By similarity). Required for palmitoylation and cell surface expression of CD36 and involved in macrophage uptake of low-density lipoprotein and in foam cell formation (By similarity). Together with ZDHHC6, required for palmitoylation of ITPR1 in immune cells, leading to regulate ITPR1 stability and function. Plays a role in protection of cells from ER stress-induced apoptosis. Protects cells from oxidative stress when overexpressed in cardiomyocytes (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006816 calcium ion transport;GO:0032469 endoplasmic reticulum calcium ion homeostasis;GO:0018345 protein palmitoylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2EN82-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q2F7Z4-1", "uniprot_id": [ { "id": "MED7_PIG", "url": "https://www.uniprot.org/uniprot/Q2F7Z4", "type": "external" } ], "mass": 27165.0, "length": 233, "protein_name": "Mediator of RNA polymerase II transcription subunit 7", "gene_name": "MED7", "organism": "Pig", "refseq_name": "mediator of RNA polymerase II transcription subunit 7", "refseq_ac": [ { "id": "NP_001038080", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038080", "type": "external" } ], "gene_names_uniprotkb": "MED7; CRSP9", "gene_names_refseq": "CRSP9; MED7", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 7; CRSP complex subunit 9; Cofactor required for Sp1 transcriptional activation subunit 9; Mediator complex subunit 7", "protein_names_refseq": "CRSP complex subunit 9; cofactor required for Sp1 transcriptional activation subunit 9; cofactor required for Sp1 transcriptional activation, subunit 9, 33kDa; mediator of RNA polymerase II transcription subunit 7", "tax_id": 9823, "disease": "", "pathway": " (ssc:733689)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16484800", "class_list": "", "function": "Chromosome mapping of 3 proteins (CRSP9, ETF1 and TMEM59) in swine, [RefSeq, PubMed]; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2F7Z6", "ec_number_list": [], "go_molecular_function": "GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0016604 nuclear body;GO:0005667 transcription regulator complex;GO:0016592 mediator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2F7Z4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q2HY40-1", "uniprot_id": [ { "id": "TXNIP_PIG", "url": "https://www.uniprot.org/uniprot/Q2HY40", "type": "external" } ], "mass": 43811.0, "length": 391, "protein_name": "Thioredoxin-interacting protein", "gene_name": "TXNIP", "organism": "Pig", "refseq_name": "thioredoxin-interacting protein", "refseq_ac": [ { "id": "NP_001038079", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038079", "type": "external" } ], "gene_names_uniprotkb": "TXNIP", "gene_names_refseq": "TXNIP", "protein_names_uniprotkb": "Thioredoxin-interacting protein", "protein_names_refseq": "thioredoxin-interacting protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:733688); (R-SSC-844456)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "17406940;23053948", "class_list": "", "function": "May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability (By similarity). Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm (By similarity). Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest (By similarity). Required for the maturation of natural killer cells (By similarity). Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1) (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Single-marker and haplotype analyses revealed significant effects of TXNIP on hot carcass weight, test daily gain, and lifetime daily gain, [RefSeq, PubMed]; The molecular characterization of porcine TXNIP gene, is described., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A5J2A7;Q09W51", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0004857 enzyme inhibitor activity;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0071228 cellular response to tumor cell;GO:0006351 DNA-templated transcription;GO:0006979 response to oxidative stress;GO:0030216 keratinocyte differentiation;GO:0051782 negative regulation of cell division", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q2HY40-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q2I689-1", "uniprot_id": [ { "id": "PLAL1_PIG", "url": "https://www.uniprot.org/uniprot/Q2I689", "type": "external" } ], "mass": 51058.0, "length": 463, "protein_name": "Zinc finger protein PLAGL1", "gene_name": "PLAGL1", "organism": "Pig", "refseq_name": "zinc finger protein PLAGL1", "refseq_ac": [ { "id": "NP_001038010", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038010", "type": "external" } ], "gene_names_uniprotkb": "PLAGL1", "gene_names_refseq": "PLAGL1", "protein_names_uniprotkb": "Zinc finger protein PLAGL1; Pleiomorphic adenoma-like protein 1", "protein_names_refseq": "pleiomorphic adenoma gene-like 1; pleiomorphic adenoma-like protein 1; zinc finger protein PLAGL1", "tax_id": 9823, "disease": "", "pathway": " (ssc:733596)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "17178803;19571260", "class_list": "", "function": "Acts as a transcriptional activator. Involved in the transcriptional regulation of type 1 receptor for pituitary adenylate cyclase-activating polypeptide., [UniProtKB, UniProtKB]; PLAGL1 is maternally imprinted in swine. Expression profiling using short-oligonucleotide microarrays of parthenotes and control fetal tissues supports imprinted isoform-specific expression., [RefSeq, PubMed]; The expression patterns of PLAGL1 and PEG10 genes in two breeds of swine are reported., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0016604 nuclear body", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0002682 regulation of immune system process;GO:0001817 regulation of cytokine production", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q2I689-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q2LE37-1", "uniprot_id": [ { "id": "APOM_PIG", "url": "https://www.uniprot.org/uniprot/Q2LE37", "type": "external" } ], "mass": 21241.0, "length": 188, "protein_name": "Apolipoprotein M", "gene_name": "APOM", "organism": "Pig", "refseq_name": "apolipoprotein M precursor", "refseq_ac": [ { "id": "NP_001035730", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035730", "type": "external" } ], "gene_names_uniprotkb": "APOM", "gene_names_refseq": "APOM", "protein_names_uniprotkb": "Apolipoprotein M; Apo-M; ApoM", "protein_names_refseq": "apo-M; apolipoprotein M precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:692188); (R-SSC-975634)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005319 lipid transporter activity;GO:0005543 phospholipid binding;GO:0016209 antioxidant activity", "go_cellular_component": "GO:0034364 high-density lipoprotein particle;GO:0034361 very-low-density lipoprotein particle;GO:0034366 spherical high-density lipoprotein particle;GO:0034362 low-density lipoprotein particle;GO:0034365 discoidal high-density lipoprotein particle", "go_biological_process": "GO:0033344 cholesterol efflux;GO:0034375 high-density lipoprotein particle remodeling;GO:0034380 high-density lipoprotein particle assembly;GO:0034384 high-density lipoprotein particle clearance;GO:0034445 negative regulation of plasma lipoprotein oxidation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2LE37-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q2MJQ7-1", "uniprot_id": [ { "id": "CCG1_PIG", "url": "https://www.uniprot.org/uniprot/Q2MJQ7", "type": "external" } ], "mass": 25093.0, "length": 224, "protein_name": "Voltage-dependent calcium channel gamma-1 subunit", "gene_name": "CACNG1", "organism": "Pig", "refseq_name": "voltage-dependent calcium channel gamma-1 subunit", "refseq_ac": [ { "id": "NP_001038070", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038070", "type": "external" } ], "gene_names_uniprotkb": "CACNG1", "gene_names_refseq": "CACNG1", "protein_names_uniprotkb": "Voltage-dependent calcium channel gamma-1 subunit; Dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma", "protein_names_refseq": "dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma; voltage-dependent calcium channel gamma subunit; voltage-dependent calcium channel gamma-1 subunit", "tax_id": 9823, "disease": "", "pathway": " (ssc:733677)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005246 calcium channel regulator activity;GO:0005245 voltage-gated calcium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0042383 sarcolemma;GO:0030315 T-tubule;GO:1990454 L-type voltage-gated calcium channel complex", "go_biological_process": "GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2MJQ7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q2MJV9-1", "uniprot_id": [ { "id": "PALMD_PIG", "url": "https://www.uniprot.org/uniprot/Q2MJV9", "type": "external" } ], "mass": 62308.0, "length": 551, "protein_name": "Palmdelphin", "gene_name": "PALMD", "organism": "Pig", "refseq_name": "palmdelphin", "refseq_ac": [ { "id": "NP_001033734", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033734", "type": "external" } ], "gene_names_uniprotkb": "PALMD", "gene_names_refseq": "PALMD", "protein_names_uniprotkb": "Palmdelphin", "protein_names_refseq": "palmdelphin", "tax_id": 9823, "disease": "", "pathway": " (ssc:654413)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0043197 dendritic spine", "go_biological_process": "GO:0008360 regulation of cell shape", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2MJV9-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q2QLE3-1", "uniprot_id": [ { "id": "TES_PIG", "url": "https://www.uniprot.org/uniprot/Q2QLE3", "type": "external" } ], "mass": 47947.0, "length": 421, "protein_name": "Testin", "gene_name": "TES", "organism": "Pig", "refseq_name": "testin", "refseq_ac": [ { "id": "NP_001116672", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116672", "type": "external" } ], "gene_names_uniprotkb": "TES", "gene_names_refseq": "TES", "protein_names_uniprotkb": "Testin", "protein_names_refseq": "testin; testis derived transcript (3 LIM domains)", "tax_id": 9823, "disease": "", "pathway": " (ssc:100125376)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12917688", "class_list": "", "function": "Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005925 focal adhesion;GO:0032991 protein-containing complex", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2QLE3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q307W6-1", "uniprot_id": [ { "id": "Q307W6_PIG", "url": "https://www.uniprot.org/uniprot/Q307W6", "type": "external" } ], "mass": 12790.0, "length": 116, "protein_name": "Cocaine- and amphetamine-regulated transcript protein", "gene_name": "CARTPT", "organism": "Pig", "refseq_name": "cocaine- and amphetamine-regulated transcript protein precursor", "refseq_ac": [ { "id": "NP_001093395", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093395", "type": "external" } ], "gene_names_uniprotkb": "CARTPT", "gene_names_refseq": "CARTPT; CART", "protein_names_uniprotkb": "Cocaine- and amphetamine-regulated transcript protein", "protein_names_refseq": "Cocaine- and amphetamine-regulated transcript protein; cocaine- and amphetamine-regulated transcript protein precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397252)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "19207928;20594191;21091201;22252754;23939195;24402755;26266486;27738989;28525332;32543654", "class_list": "", "function": "CART-LI perikarya decreased in myenteric plexus of the gastric antrum, corpus, and pylorus in experimental diabetes. Acute hyperglycemia reduced CART expression in enteric perikarya and decreased CART-LI fiber density in gastric antrum circular muscle., [RefSeq, PubMed]; CgA and CgB have been used as general NEN biomarkers for many years, while CART has only recently been identified, [RefSeq, PubMed]; Distribution and chemical coding pattern of the cocaine- and amphetamine-regulated transcript (CART) immunoreactivity in the preoptic area of the pig, [RefSeq, PubMed]; In every amygdaloid region the CART-immunoreactive neurons formed a heterogeneous population consisting mostly of small, rounded or slightly elongated cell bodies, with a few poorly branched, smooth dendrites., [RefSeq, PubMed]; Results show that even low doses of T-2 toxin may change the expression of CART in the nervous system, and confirms that CART seems to be an important neuronal factor within the enteric nervous system, which takes part in regulation of intestinal functions both in physiological conditions and during pathological states., [RefSeq, PubMed]; The chromosome region harbouring the CART gene is a promising quantitative trait loci for pig production traits., [RefSeq, PubMed]; The present study reports for the first time on the co-localisation of CART and VIP in myenteric neurons of the porcine transverse colon., [RefSeq, PubMed]; The regulation of the pig CART gene, [RefSeq, PubMed]; This study showed that CART present in the pelvic plexus (PP) may influence the activity of pelvic ganglionic neurons/SIF cells, that the PP should be considered as a potential source of CART-like supply to pelvic viscera, and that functional interactions between CART and substance P or PACAP are possible at the periphery., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1SK14", "ec_number_list": [], "go_molecular_function": "GO:0005184 neuropeptide hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0030141 secretory granule;GO:0045202 synapse", "go_biological_process": "GO:0007218 neuropeptide signaling pathway;GO:0043410 positive regulation of MAPK cascade;GO:0045777 positive regulation of blood pressure;GO:0007268 chemical synaptic transmission;GO:0051971 positive regulation of transmission of nerve impulse", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q307W6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q30C86-1", "uniprot_id": [ { "id": "ADIG_PIG", "url": "https://www.uniprot.org/uniprot/Q30C86", "type": "external" } ], "mass": 9549.0, "length": 81, "protein_name": "Adipogenin", "gene_name": "ADIG", "organism": "Pig", "refseq_name": "adipogenin isoform 1", "refseq_ac": [ { "id": "NP_001032353", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032353", "type": "external" } ], "gene_names_uniprotkb": "ADIG; SMAF1", "gene_names_refseq": "ADIG; SMAF-1; SMAF1", "protein_names_uniprotkb": "Adipogenin; SMAF-1; Small adipocyte factor 1", "protein_names_refseq": "adipogenin isoform 1; small adipocyte factor 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:641357)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Key regulator of lipid storage that promotes the expansion of lipid droplets during the formation of mature adipocytes. Acts by forming a dodecameric complex with seipin (BSCL2) when adipocytes have differentiated and are undergoing maturation. In the dodecameric complex, ADIG antagonizes the activity of BSCL2 by reducing BSCL2-mediated triacylglycerol nucleation and relieving BSCL2's inhibition of GPAT3 and GPAT4. GPAT3 and GPAT4 then translocate to lipid droplets, promoting the synthesis of triacylglycerols and the expansion of lipid droplets., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005811 lipid droplet;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0007283 spermatogenesis;GO:0045600 positive regulation of fat cell differentiation;GO:0050872 white fat cell differentiation;GO:0050873 brown fat cell differentiation;GO:0019915 lipid storage", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q30C86-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q33BP8-1", "uniprot_id": [ { "id": "FOXN3_PIG", "url": "https://www.uniprot.org/uniprot/Q33BP8", "type": "external" } ], "mass": 53307.0, "length": 485, "protein_name": "Forkhead box protein N3", "gene_name": "FOXN3", "organism": "Pig", "refseq_name": "forkhead box protein N3", "refseq_ac": [ { "id": "NP_001038001", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038001", "type": "external" } ], "gene_names_uniprotkb": "FOXN3; CHES1", "gene_names_refseq": "CHES1; FOXN3", "protein_names_uniprotkb": "Forkhead box protein N3; Checkpoint suppressor 1", "protein_names_refseq": "checkpoint suppressor 1; forkhead box protein N3", "tax_id": 9823, "disease": "", "pathway": " (ssc:733584)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16573525;29672877", "class_list": "", "function": "ARHGEF10 and FOXN3 are genes potentially involved in hair development and growth, [RefSeq, PubMed]; Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints) (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000987 cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q33BP8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q35914-1", "uniprot_id": [ { "id": "ATP8_PIG", "url": "https://www.uniprot.org/uniprot/Q35914", "type": "external" } ], "mass": 7947.0, "length": 67, "protein_name": "ATP synthase F(0) complex subunit 8", "gene_name": "MT-ATP8", "organism": "Pig", "refseq_name": "ATP synthase F0 subunit 8", "refseq_ac": [ { "id": "NP_008638", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_008638", "type": "external" } ], "gene_names_uniprotkb": "MT-ATP8; ATP8; ATPASE8; MTATP8", "gene_names_refseq": "ATP8", "protein_names_uniprotkb": "ATP synthase F(0) complex subunit 8; A6L; F-ATPase subunit 8", "protein_names_refseq": "ATP synthase F0 subunit 8", "tax_id": 9823, "disease": "", "pathway": " (ssc:808505); (R-SSC-163210); (R-SSC-5419276); (R-SSC-8949613)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "10433971;3017295;9732457;9734874", "class_list": "", "function": "Subunit 8, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). Part of the complex F(0) domain (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O79877;O99387", "ec_number_list": [], "go_molecular_function": "GO:0015078 proton transmembrane transporter activity", "go_cellular_component": "GO:0031966 mitochondrial membrane;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0042776 proton motive force-driven mitochondrial ATP synthesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q35914-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q35915-1", "uniprot_id": [ { "id": "ATP6_PIG", "url": "https://www.uniprot.org/uniprot/Q35915", "type": "external" } ], "mass": 25039.0, "length": 226, "protein_name": "ATP synthase F(0) complex subunit a", "gene_name": "MT-ATP6", "organism": "Pig", "refseq_name": "ATP synthase F0 subunit 6", "refseq_ac": [ { "id": "NP_008639", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_008639", "type": "external" } ], "gene_names_uniprotkb": "MT-ATP6; ATP6; ATPASE6; MTATP6", "gene_names_refseq": "ATP6", "protein_names_uniprotkb": "ATP synthase F(0) complex subunit a; F-ATPase protein 6; Proton-conducting channel, ATP synthase F(0) complex subunit a", "protein_names_refseq": "ATP synthase F0 subunit 6", "tax_id": 9823, "disease": "", "pathway": " (ssc:808506); (R-SSC-163210); (R-SSC-5419276); (R-SSC-8949613); (R-SSC-9837999)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "10433971;3017295;9732457", "class_list": "", "function": "Subunit a, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. With the subunit c (ATP5MC1), forms the proton-conducting channel in the F(0) domain, that contains two crucial half-channels (inlet and outlet) that facilitate proton movement from the mitochondrial intermembrane space (IMS) into the matrix. Protons are taken up via the inlet half-channel and released through the outlet half-channel, following a Grotthuss mechanism., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O79878", "ec_number_list": [], "go_molecular_function": "GO:0015252 proton channel activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0015986 proton motive force-driven ATP synthesis;GO:1902600 proton transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q35915-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q35916-1", "uniprot_id": [ { "id": "COX3_PIG", "url": "https://www.uniprot.org/uniprot/Q35916", "type": "external" } ], "mass": 29728.0, "length": 261, "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "MT-CO3", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "MT-CO3; COIII; COXIII; MTCO3", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytochrome c oxidase subunit 3; 7.1.1.9; Cytochrome c oxidase polypeptide III", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:808507); (R-SSC-5419276); (R-SSC-5628897); (R-SSC-611105); (R-SSC-9707564); (R-SSC-9864848)", "pathway_count": 6, "publication_count": 3, "publication_id_list": "10433971;3017295;9732457", "class_list": "", "function": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O79879", "ec_number_list": [], "go_molecular_function": "GO:0004129 cytochrome-c oxidase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045277 respiratory chain complex IV", "go_biological_process": "GO:0006123 mitochondrial electron transport, cytochrome c to oxygen;GO:0008535 respiratory chain complex IV assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q35916-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q3MQ04-1", "uniprot_id": [ { "id": "ATG5_PIG", "url": "https://www.uniprot.org/uniprot/Q3MQ04", "type": "external" } ], "mass": 32433.0, "length": 275, "protein_name": "Autophagy protein 5", "gene_name": "ATG5", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ATG5", "gene_names_refseq": "", "protein_names_uniprotkb": "Autophagy protein 5", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway. As part of the ATG8 conjugation system with ATG12 and ATG16L1, required for recruitment of LRRK2 to stressed lysosomes and induction of LRRK2 kinase activity in response to lysosomal stress (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005776 autophagosome;GO:0005930 axoneme;GO:0034045 phagophore assembly site membrane;GO:0034274 Atg12-Atg5-Atg16 complex;GO:0061908 phagophore", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0006915 apoptotic process;GO:0006914 autophagy;GO:0043069 negative regulation of programmed cell death;GO:0000423 mitophagy", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3MQ04-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q3YFL6-1", "uniprot_id": [ { "id": "MYF6_PIG", "url": "https://www.uniprot.org/uniprot/Q3YFL6", "type": "external" } ], "mass": 26952.0, "length": 242, "protein_name": "Myogenic factor 6", "gene_name": "MYF6", "organism": "Pig", "refseq_name": "myogenic factor 6", "refseq_ac": [ { "id": "NP_001231601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231601", "type": "external" } ], "gene_names_uniprotkb": "MYF6", "gene_names_refseq": "MYF6; Myf-6", "protein_names_uniprotkb": "Myogenic factor 6; Myf-6", "protein_names_refseq": "eukaryotic myogenic factor MYF-6; myogenic factor 6", "tax_id": 9823, "disease": "", "pathway": " (ssc:397005); (R-SSC-525793)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "15595701;16682754;20888930;21749918", "class_list": "", "function": "Associations between the genotype at the MYF6 locus and carcass quality traits appeared to be breed-dependent., [RefSeq, PubMed]; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity)., [UniProtKB]; Pietrain pigs exhibited significant higher expression of MYF6 and hypermethylated E2F1 binding element within MYF6 5'-regulatory region as compared with Duroc pigs., [RefSeq, PubMed]; The expression level of Myf6 gene does not indicate significant differences between muscles, ages and breeds., [RefSeq, PubMed]; The porcine MYF6 gene was amplified and sequenced and compared with MYF6 gene sequences of other species. The amino acid sequence was deduced and an interspecies homology analysis was performed., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7YRC4", "ec_number_list": [], "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0035914 skeletal muscle cell differentiation;GO:0048743 positive regulation of skeletal muscle fiber development;GO:0045663 positive regulation of myoblast differentiation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q3YFL6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q3ZDR4-1", "uniprot_id": [ { "id": "CD70_PIG", "url": "https://www.uniprot.org/uniprot/Q3ZDR4", "type": "external" } ], "mass": 21275.0, "length": 190, "protein_name": "CD70 antigen", "gene_name": "CD70", "organism": "Pig", "refseq_name": "CD70 antigen", "refseq_ac": [ { "id": "NP_001037996", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001037996", "type": "external" } ], "gene_names_uniprotkb": "CD70; CD27L", "gene_names_refseq": "CD70; TNFSF7", "protein_names_uniprotkb": "CD70 antigen; CD27 ligand; CD27-L", "protein_names_refseq": "CD27 ligand; CD27-L; CD70 antigen; tumor necrosis factor ligand superfamily member 7", "tax_id": 9823, "disease": "", "pathway": " (ssc:733577)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells. The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0048018 receptor ligand activity;GO:0005164 tumor necrosis factor receptor binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0042110 T cell activation;GO:0033209 tumor necrosis factor-mediated signaling pathway;GO:0046651 lymphocyte proliferation;GO:0090717 adaptive immune memory response involving T cells and B cells;GO:0160162 CD27 signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZDR4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q45KW7-1", "uniprot_id": [ { "id": "FABPI_PIG", "url": "https://www.uniprot.org/uniprot/Q45KW7", "type": "external" } ], "mass": 15217.0, "length": 132, "protein_name": "Fatty acid-binding protein, intestinal", "gene_name": "FABP2", "organism": "Pig", "refseq_name": "fatty acid-binding protein, intestinal", "refseq_ac": [ { "id": "NP_001026950", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026950", "type": "external" } ], "gene_names_uniprotkb": "FABP2; FABPI", "gene_names_refseq": "FABP2; I-FABP", "protein_names_uniprotkb": "Fatty acid-binding protein, intestinal; Fatty acid-binding protein 2; I-FABP; Intestinal-type fatty acid-binding protein", "protein_names_refseq": "fatty acid-binding protein, intestinal; intestinal fatty acid binding protein; intestinal-type fatty acid-binding protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:595106); (R-SSC-163560)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "16529296;18708596;19207930", "class_list": "", "function": "Association analyses of the FABP2:g.412T>C with fatty acid composition traits were not significant in simple association., [RefSeq, PubMed]; FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor (By similarity)., [UniProtKB]; Plasma I-FABP concentration showed great variation within treatments, and no difference was observed in plasma I-FABP concentrations between the weaned conventionally and unweaned treatments, [RefSeq, PubMed]; The full-length cDNA of I-FABP was cloned from intestine and the mRNA was extensively present in various tissues, but I-FABP transcript of approximately 620 bp was more abundant in intestine than in other tissues., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q56G53", "ec_number_list": [], "go_molecular_function": "GO:0036041 long-chain fatty acid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0015908 fatty acid transport;GO:0098856 intestinal lipid absorption", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q45KW7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q49I35-1", "uniprot_id": [ { "id": "LEG1_PIG", "url": "https://www.uniprot.org/uniprot/Q49I35", "type": "external" } ], "mass": 14694.0, "length": 135, "protein_name": "Galectin-1", "gene_name": "LGALS1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LGALS1", "gene_names_refseq": "", "protein_names_uniprotkb": "Galectin-1; Gal-1; Lectin galactoside-binding soluble 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043236 laminin binding;GO:0030395 lactose binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm", "go_biological_process": "GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q49I35-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q4KRV1-1", "uniprot_id": [ { "id": "GPI8_PIG", "url": "https://www.uniprot.org/uniprot/Q4KRV1", "type": "external" } ], "mass": 45142.0, "length": 395, "protein_name": "GPI-anchor transamidase", "gene_name": "PIGK", "organism": "Pig", "refseq_name": "GPI-anchor transamidase precursor", "refseq_ac": [ { "id": "NP_001027529", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027529", "type": "external" } ], "gene_names_uniprotkb": "PIGK", "gene_names_refseq": "PIGK", "protein_names_uniprotkb": "GPI-anchor transamidase; 2.6.1.-; GPI-anchor transamidase component PIGK; PIG-K; Phosphatidylinositol-glycan biosynthesis class K protein", "protein_names_refseq": "GPI transamidase; GPI-anchor transamidase component PIGK; GPI-anchor transamidase precursor; GPI-anchor transamidase; PIG-K; phosphatidylinositol glycan class K; phosphatidylinositol-glycan biosynthesis class K protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:606750)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalytic subunit of the glycosylphosphatidylinositol-anchor (GPI-anchor) transamidase (GPI-T) complex that catalyzes the formation of the linkage between a proprotein and a GPI-anchor and participates in GPI anchored protein biosynthesis. Recognizes diverse proproteins at a C-terminal signal peptide (CSP) region that lacks consensus sequence and replaces it with a GPI-anchor via a transamidation reaction. Transamidation catalysis reaction follows a two-phase mechanism. In the acyl-enzyme phase, the carbonyl group of the proproteins's omega-site undergoes a nucleophilic attack forming an enzyme-substrate thioester bond. Followed by a general acid catalysis that allows CSP releasing, regenerating the carbonyl, and forming the acyl-enzyme intermediate. In the GPI-anchor attachment phase, the amino group of the GPI-anchor's ethanolamine phosphate, the one on third mannose (EtNP3), mediates a nucleophilic attack on the carbonyl of the acyl-enzyme intermediate, replacing the CSP, allowing GPI-anchor attachment to the omega-residue, therefore forming the product and freeing the enzyme., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003923 GPI-anchor transamidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0042765 GPI-anchor transamidase complex", "go_biological_process": "GO:0006508 proteolysis;GO:0006506 GPI anchor biosynthetic process;GO:0016255 attachment of GPI anchor to protein", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q4KRV1-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q4PLW0-1", "uniprot_id": [ { "id": "PLIN2_PIG", "url": "https://www.uniprot.org/uniprot/Q4PLW0", "type": "external" } ], "mass": 50196.0, "length": 459, "protein_name": "Perilipin-2", "gene_name": "PLIN2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PLIN2; ADFP; ADRP", "gene_names_refseq": "", "protein_names_uniprotkb": "Perilipin-2; ADRP; Adipophilin; Adipose differentiation-related protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "16167998", "class_list": "", "function": "Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005622 intracellular anatomical structure;GO:0005811 lipid droplet;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0042149 cellular response to glucose starvation;GO:0010890 positive regulation of triglyceride storage;GO:0019915 lipid storage;GO:1905691 lipid droplet disassembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q4PLW0-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q4VYA0-1", "uniprot_id": [ { "id": "DYLT4_PIG", "url": "https://www.uniprot.org/uniprot/Q4VYA0", "type": "external" } ], "mass": 22840.0, "length": 219, "protein_name": "Dynein light chain Tctex-type 4", "gene_name": "DYNLT4", "organism": "Pig", "refseq_name": "dynein light chain Tctex-type 4", "refseq_ac": [ { "id": "NP_001027527", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027527", "type": "external" } ], "gene_names_uniprotkb": "DYNLT4; TCTEX1D4", "gene_names_refseq": "DYNLT4; N22.1; TCTEX1D4; Tctex-2-beta", "protein_names_uniprotkb": "Dynein light chain Tctex-type 4; Protein N22.1; Tctex-2-beta; Tctex1 domain-containing protein 4", "protein_names_refseq": "Tctex1 domain containing 4; Tctex1 domain-containing protein 4; dynein light chain Tctex-type 4; protein N22.1", "tax_id": 9823, "disease": "", "pathway": " (ssc:606747)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16982625", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0045505 dynein intermediate chain binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031514 motile cilium;GO:0001669 acrosomal vesicle;GO:0005815 microtubule organizing center", "go_biological_process": "GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q4VYA0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q52NJ0-1", "uniprot_id": [ { "id": "PRAF1_PIG", "url": "https://www.uniprot.org/uniprot/Q52NJ0", "type": "external" } ], "mass": 20665.0, "length": 185, "protein_name": "Prenylated Rab acceptor protein 1", "gene_name": "RABAC1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "RABAC1; PRAF1", "gene_names_refseq": "", "protein_names_uniprotkb": "Prenylated Rab acceptor protein 1; PRA1 family protein 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:595125)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI1., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0008021 synaptic vesicle", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q52NJ0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q58DD9-1", "uniprot_id": [ { "id": "GPN2_PIG", "url": "https://www.uniprot.org/uniprot/Q58DD9", "type": "external" } ], "mass": 34576.0, "length": 310, "protein_name": "GPN-loop GTPase 2", "gene_name": "GPN2", "organism": "Pig", "refseq_name": "GPN-loop GTPase 2", "refseq_ac": [ { "id": "XP_003127766", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003127766", "type": "external" } ], "gene_names_uniprotkb": "GPN2; ATPBD1B", "gene_names_refseq": "GPN2", "protein_names_uniprotkb": "GPN-loop GTPase 2; 3.6.5.-; ATP-binding domain 1 family member B", "protein_names_refseq": "GPN-loop GTPase 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:110255194)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16305752;23150988", "class_list": "", "function": "Small GTPase involved in the correct assembly of RNA polymerase RNA polymerase II and III (RNAPII and RNAPIII) complexes, ensuring their proper nuclear import., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q58DD9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q59HI6-1", "uniprot_id": [ { "id": "Q59HI6_PIG", "url": "https://www.uniprot.org/uniprot/Q59HI6", "type": "external" } ], "mass": 91460.0, "length": 796, "protein_name": "Toll like receptor 6", "gene_name": "TLR6", "organism": "Pig", "refseq_name": "toll-like receptor 6", "refseq_ac": [ { "id": "NP_998925", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998925", "type": "external" } ], "gene_names_uniprotkb": "TLR6", "gene_names_refseq": "TLR-6; TLR6", "protein_names_uniprotkb": "Toll like receptor 6", "protein_names_refseq": "toll-like receptor 6", "tax_id": 9823, "disease": "", "pathway": " (ssc:396621); (R-SSC-5686938)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "14585198;16263171;19953243;32543654", "class_list": "", "function": "Both TLR2 and TLR6 are important in the recognition of M. hyopneumoniae in porcine alveolar macrophages, [RefSeq, PubMed]; In total, 20, 27, and 26 SNPs were detected in TLR1, TLR2, and TLR6, respectively; SNPs detected in TLR6 may represent species-specific function on the protein level in the wild boars and domestic pigs., [RefSeq, PubMed]; Phylogenetic analysis of the cytoplasmic regions of TLR genes suggested that the signal transduction pathway of TLR10 was different from those of TLR1 and TLR6, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0042802 identical protein binding;GO:0046982 protein heterodimerization activity;GO:0071723 lipopeptide binding;GO:0042498 diacyl lipopeptide binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0045121 membrane raft;GO:0035355 Toll-like receptor 2-Toll-like receptor 6 protein complex", "go_biological_process": "GO:0043032 positive regulation of macrophage activation;GO:0034136 negative regulation of toll-like receptor 2 signaling pathway;GO:0006954 inflammatory response;GO:0045429 positive regulation of nitric oxide biosynthetic process;GO:1904646 cellular response to amyloid-beta", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q59HI6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5FY69-1", "uniprot_id": [ { "id": "SC5AA_PIG", "url": "https://www.uniprot.org/uniprot/Q5FY69", "type": "external" } ], "mass": 64437.0, "length": 597, "protein_name": "Sodium/mannose cotransporter SLC5A10", "gene_name": "SLC5A10", "organism": "Pig", "refseq_name": "sodium/mannose cotransporter SLC5A10", "refseq_ac": [ { "id": "NP_001012297", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012297", "type": "external" } ], "gene_names_uniprotkb": "SLC5A10; SGLT1; SGLT5", "gene_names_refseq": "SGLT1; SGLT5; SLC5A10; SLC5A1", "protein_names_uniprotkb": "Sodium/mannose cotransporter SLC5A10; Na(+)/glucose cotransporter 5; Sodium/glucose cotransporter 5; Solute carrier family 5 member 10", "protein_names_refseq": "Na(+)/glucose cotransporter 5; sodium/glucose cotransporter 5; sodium/mannose cotransporter SLC5A10; solute carrier family 5 (sodium/glucose cotransporter), member 10", "tax_id": 9823, "disease": "", "pathway": " (ssc:497235)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "15777622;16259605;21030609;21454867;22683689;27264891;27851758;32070687", "class_list": "", "function": "Decreased NHE3 activity and trafficking in TGEV-infected IPEC-J2 cells via the SGLT1-mediated P38 MAPK/AKt2 pathway., [RefSeq, PubMed]; Electrogenic Na+-coupled sugar symporter that actively transports D-mannose or D-fructose at the plasma membrane, with a Na+ to sugar coupling ratio of 1:1. Transporter activity is driven by a transmembrane Na+ electrochemical gradient set by the Na+/K+ pump. Exclusively recognizes sugar substrates having a pyranose ring with an axial hydroxyl group on carbon 2 (By similarity). Has likely evolved to enable renal reabsorption of D-mannose, an important constituent of oligosaccharide chains of glycoproteins. Contributes to dietary D-fructose reabsorption from glomerular filtrate across the brush border of the kidney (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Expression of SLGT1 was evaluated in LLC-PK1 cells grown on porous membranes for the development of an artificial kidney., [RefSeq, PubMed]; Feed intake remains low whereas respiratory frequency and body temperature remain higher and expression of HSP90, CAT1, SGLT1 and GLUT4 increases in some tissues in pigs under chronic heat stress conditions., [RefSeq, PubMed]; In accord with a rise in methyl alpha-D-glucopyranoside uptake activity, the mRNA and protein levels of SGLT1 were apparently up-regulated in the presence of apoE3, [RefSeq, PubMed]; Neonates have high intestinal apical SGLT1 uptake activity by abundantly expressing SGLT1 protein in epithelia and on apical membrane along the entire crypt-villus axis in association with enhanced protein translational control mechanisms in crypt cells., [RefSeq, PubMed]; The effects of Transmissible gastroenteritis virus infection on glucose uptake and SGLT1 and GLUT2 expression, are reported. Publication Status: Online-Only, [RefSeq, PubMed]; The increased expression of SGLT1 in the jejunum by phytase supplementation implies that phytase alleviated the negative effects of phytic acid partly through increased expression of SGLT1., [RefSeq, PubMed]; The segmental differences in porcine glucose transport characteristics may be based on direct or indirect modulations of SGLT1 activity., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0140929 mannose:sodium symporter activity;GO:0140930 fructose:sodium symporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q5FY69-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5G6V9-1", "uniprot_id": [ { "id": "COF2_PIG", "url": "https://www.uniprot.org/uniprot/Q5G6V9", "type": "external" } ], "mass": 18737.0, "length": 166, "protein_name": "Cofilin-2", "gene_name": "CFL2", "organism": "Pig", "refseq_name": "cofilin-2", "refseq_ac": [ { "id": "NP_001020386", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020386", "type": "external" } ], "gene_names_uniprotkb": "CFL2", "gene_names_refseq": "CFL2", "protein_names_uniprotkb": "Cofilin-2; Cofilin, muscle isoform", "protein_names_refseq": "cofilin-2", "tax_id": 9823, "disease": "", "pathway": " (ssc:497233)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "19123043", "class_list": "", "function": "Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere (By similarity)., [UniProtKB, UniProtKB]; Examined the expression of MyHC 2x, MyHC 2b and MyHC1/slow in C2C12 cells expressing CFL2b. Results showed the level of MyHC 2x and MyHC 2b mRNA were dramatically increased compared with control cells, while the level of MyHC1/slow mRNA is not changed., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0015629 actin cytoskeleton;GO:0016363 nuclear matrix;GO:0030018 Z disc", "go_biological_process": "GO:0051014 actin filament severing;GO:0007519 skeletal muscle tissue development;GO:0030042 actin filament depolymerization;GO:0030043 actin filament fragmentation;GO:0030836 positive regulation of actin filament depolymerization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5G6V9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5I921-1", "uniprot_id": [ { "id": "Q5I921_PIG", "url": "https://www.uniprot.org/uniprot/Q5I921", "type": "external" } ], "mass": 27132.0, "length": 236, "protein_name": "Sex-determining region Y protein", "gene_name": "", "organism": "Pig", "refseq_name": "sex-determining region Y protein", "refseq_ac": [ { "id": "XP_013842032", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013842032", "type": "external" } ], "gene_names_uniprotkb": "", "gene_names_refseq": "LOC106504154", "protein_names_uniprotkb": "Sex-determining region Y protein", "protein_names_refseq": "sex-determining region Y protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:106504154)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. Involved in different aspects of gene regulation including promoter activation or repression. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending. Also involved in pre-mRNA splicing. In male adult brain involved in the maintenance of motor functions of dopaminergic neurons., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016607 nuclear speck", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007548 sex differentiation;GO:0030238 male sex determination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q5I921-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5PXT2-1", "uniprot_id": [ { "id": "LMCD1_PIG", "url": "https://www.uniprot.org/uniprot/Q5PXT2", "type": "external" } ], "mass": 40660.0, "length": 363, "protein_name": "LIM and cysteine-rich domains protein 1", "gene_name": "LMCD1", "organism": "Pig", "refseq_name": "LIM and cysteine-rich domains protein 1", "refseq_ac": [ { "id": "NP_001008692", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008692", "type": "external" } ], "gene_names_uniprotkb": "LMCD1", "gene_names_refseq": "LMCD1", "protein_names_uniprotkb": "LIM and cysteine-rich domains protein 1", "protein_names_refseq": "LIM and cysteine-rich domains protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:494020); (R-SSC-5683826)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16331329", "class_list": "", "function": "Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter. Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0010611 regulation of cardiac muscle hypertrophy;GO:0070886 positive regulation of calcineurin-NFAT signaling cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5PXT2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5S1V9-1", "uniprot_id": [ { "id": "IL27A_PIG", "url": "https://www.uniprot.org/uniprot/Q5S1V9", "type": "external" } ], "mass": 26643.0, "length": 239, "protein_name": "Interleukin-27 subunit alpha", "gene_name": "IL27", "organism": "Pig", "refseq_name": "interleukin-27 subunit alpha precursor", "refseq_ac": [ { "id": "NP_001007521", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007521", "type": "external" } ], "gene_names_uniprotkb": "IL27; IL27A", "gene_names_refseq": "IL-27p28; IL27A; IL27", "protein_names_uniprotkb": "Interleukin-27 subunit alpha; IL-27 subunit alpha; IL-27-A; IL27-A; p28", "protein_names_refseq": "IL-27 subunit alpha; IL-27-A; IL27-A; Interleukin-27 p28 subunit; Interleukin-27 subunit alpha; interleukin 27 p28 subunit; interleukin-27 subunit alpha precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:493187)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "19269039", "class_list": "", "function": "Associates with EBI3 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. Cytokine with pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR which appears to be required but not sufficient for IL-27-mediated signal transduction. IL-27 potentiate the early phase of TH1 response and suppress TH2 and TH17 differentiation. It induces the differentiation of TH1 cells via two distinct pathways, p38 MAPK/TBX21- and ICAM1/ITGAL/ERK-dependent pathways. It also induces STAT1, STAT3, STAT4 and STAT5 phosphorylation and activates TBX21/T-Bet via STAT1 with resulting IL12RB2 up-regulation, an event crucial to TH1 cell commitment. It suppresses the expression of GATA3, the inhibitor TH1 cells development. In CD8 T-cells, it activates STATs as well as GZMB. IL-27 reveals to be a potent inhibitor of TH17 cell development and of IL-17 production. Indeed IL27 alone is also able to inhibit the production of IL17 by CD4 and CD8 T-cells. While IL-27 suppressed the development of pro-inflammatory Th17 cells via STAT1, it inhibits the development of anti-inflammatory inducible regulatory T-cells, iTreg, independently of STAT1. IL-27 also has an effect on cytokine production, it suppresses pro-inflammatory cytokine production such as IL2, IL4, IL5 and IL6 and activates suppressors of cytokine signaling such as SOCS1 and SOCS3. Apart from suppression of cytokine production, IL-27 also antagonizes the effects of some cytokines such as IL6 through direct effects on T-cells. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines such as IP-10/CXCL10 and MIG/CXCL9. In vein endothelial cells, it induces IRF1/interferon regulatory factor 1 and increase the expression of MHC class II transactivator/CIITA with resulting up-regulation of major histocompatibility complex class II (By similarity)., [UniProtKB]; The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%)., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0045523 interleukin-27 receptor binding;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005829 cytosol", "go_biological_process": "GO:0045625 regulation of T-helper 1 cell differentiation;GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0042129 regulation of T cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5S1V9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5S3G4-1", "uniprot_id": [ { "id": "COX5B_PIG", "url": "https://www.uniprot.org/uniprot/Q5S3G4", "type": "external" } ], "mass": 13783.0, "length": 129, "protein_name": "Cytochrome c oxidase subunit 5B, mitochondrial", "gene_name": "COX5B", "organism": "Pig", "refseq_name": "cytochrome c oxidase subunit 5B, mitochondrial precursor", "refseq_ac": [ { "id": "NP_001007518", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007518", "type": "external" } ], "gene_names_uniprotkb": "COX5B", "gene_names_refseq": "COX5B", "protein_names_uniprotkb": "Cytochrome c oxidase subunit 5B, mitochondrial; Cytochrome c oxidase polypeptide Vb", "protein_names_refseq": "cytochrome c oxidase polypeptide Vb; cytochrome c oxidase subunit 5B, mitochondrial precursor; cytochrome c oxidase subunit 5B, mitochondrial", "tax_id": 9823, "disease": "", "pathway": " (ssc:492822); (R-SSC-5628897); (R-SSC-611105); (R-SSC-9707564); (R-SSC-9837999); (R-SSC-9864848)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045277 respiratory chain complex IV", "go_biological_process": "GO:0006123 mitochondrial electron transport, cytochrome c to oxygen", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q5S3G4-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5XLD3-1", "uniprot_id": [ { "id": "KCRM_PIG", "url": "https://www.uniprot.org/uniprot/Q5XLD3", "type": "external" } ], "mass": 43059.0, "length": 381, "protein_name": "Creatine kinase M-type", "gene_name": "CKM", "organism": "Pig", "refseq_name": "creatine kinase M-type", "refseq_ac": [ { "id": "NP_001123421", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001123421", "type": "external" } ], "gene_names_uniprotkb": "CKM", "gene_names_refseq": "CKM; CPK-M", "protein_names_uniprotkb": "Creatine kinase M-type; 2.7.3.2; CPK-M; Creatine kinase M chain; Creatine phosphokinase M-type; M-CK", "protein_names_refseq": "M-CK; creatine kinase M chain; creatine kinase M-type; creatine phosphokinase M-type; muscle creatine kinase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397264); (R-SSC-71288)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "27606901", "class_list": "", "function": "Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa., [UniProtKB, UniProtKB]; This study examined the heterogeneity of creatine kinase (CK) forward flux rate of hearts with postinfarction left ventricular (LV) remodeling. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q45EW9", "ec_number_list": [], "go_molecular_function": "GO:0004111 creatine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0046314 phosphocreatine biosynthetic process;GO:0009408 response to heat", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5XLD3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q5YA25-1", "uniprot_id": [ { "id": "P2RY2_PIG", "url": "https://www.uniprot.org/uniprot/Q5YA25", "type": "external" } ], "mass": 41651.0, "length": 373, "protein_name": "P2Y purinoceptor 2", "gene_name": "P2RY2", "organism": "Pig", "refseq_name": "P2Y purinoceptor 2", "refseq_ac": [ { "id": "NP_001006591", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006591", "type": "external" } ], "gene_names_uniprotkb": "P2RY2", "gene_names_refseq": "P2RY2; P2Y2R; P2Y2", "protein_names_uniprotkb": "P2Y purinoceptor 2; P2Y2", "protein_names_refseq": "P2Y purinoceptor 2; P2Y2 nucleotide receptor; P2Y2 receptor", "tax_id": 9823, "disease": "", "pathway": " (ssc:450248); (R-SSC-416476); (R-SSC-417957); (R-SSC-5683826); (R-SSC-9856530)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "15280443;23567840", "class_list": "", "function": "Receptor for ATP and UTP coupled to G proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP > ATP., [UniProtKB, PubMed]; The effect of ATP on Na+-ATPase activity could be involved in antinatriuresis induced by P2Y4 receptor or a mechanism to counterbalance the natriuretic effect of P2Y2 receptor, promoting fine control of sodium reabsorption in proximal tubule cells., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031686 A1 adenosine receptor binding;GO:0045030 G protein-coupled UTP receptor activity;GO:0045028 G protein-coupled purinergic nucleotide receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0097746 blood vessel diameter maintenance;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0070257 positive regulation of mucus secretion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q5YA25-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q60I29-1", "uniprot_id": [ { "id": "IL17_PIG", "url": "https://www.uniprot.org/uniprot/Q60I29", "type": "external" } ], "mass": 17312.0, "length": 153, "protein_name": "Interleukin-17A", "gene_name": "IL17A", "organism": "Pig", "refseq_name": "interleukin-17A precursor", "refseq_ac": [ { "id": "NP_001005729", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005729", "type": "external" } ], "gene_names_uniprotkb": "IL17A; IL17", "gene_names_refseq": "IL17A; IL17", "protein_names_uniprotkb": "Interleukin-17A; IL-17A; IL-17", "protein_names_refseq": "IL-17A; IL-17; interleukin-17A precursor; interleukin-17", "tax_id": 9823, "disease": "", "pathway": " (ssc:449530)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15450131;22321808;23365350;25040151;31614911", "class_list": "", "function": "Alterations in the IL-17 regulated pathway of porcine colon in response to dietary supplementation with seaweeds and yeast are reported., [RefSeq, PubMed]; At week 15, skin cell infiltrates from pigs with crusted scabies had significantly higher CD8+ T cell, gammadelta T cell and IL-17+ cell numbers than those with ordinary scabies. Peripheral IL-17 levels were not increased, suggesting that localized skin IL-17-secreting T cells may play a critical role in the pathogenesis of crusted scabies development., [RefSeq, PubMed]; Cloning and expression of interleukin-17., [RefSeq, PubMed]; Conclude that only two subpopulations of porcine WBCs are sources of IL-17 after non-specific stimulation: CD3(+)CD4(+) and CD3(+)gammadeltaTCR(+)., [RefSeq, PubMed]; Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity. Signals via IL17RA-IL17RC heterodimeric receptor complex, triggering homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter. This leads to downstream TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways ultimately resulting in transcriptional activation of cytokines, chemokines, antimicrobial peptides and matrix metalloproteinases, with potential strong immune inflammation. Plays an important role in connecting T cell-mediated adaptive immunity and acute inflammatory response to destroy extracellular bacteria and fungi. As a signature effector cytokine of T-helper 17 cells (Th17), primarily induces neutrophil activation and recruitment at infection and inflammatory sites. In airway epithelium, mediates neutrophil chemotaxis via induction of CXCL1 and CXCL5 chemokines. In secondary lymphoid organs, contributes to germinal center formation by regulating the chemotactic response of B cells to CXCL12 and CXCL13, enhancing retention of B cells within the germinal centers, B cell somatic hypermutation rate and selection toward plasma cells. Effector cytokine of a subset of gamma-delta T cells that functions as part of an inflammatory circuit downstream IL1B, TLR2 and IL23A-IL12B to promote neutrophil recruitment for efficient bacterial clearance. Effector cytokine of innate immune cells including invariant natural killer cell (iNKT) and group 3 innate lymphoid cells that mediate initial neutrophilic inflammation. Involved in the maintenance of the integrity of epithelial barriers during homeostasis and pathogen infection. Upon acute injury, has a direct role in epithelial barrier formation by regulating OCLN localization and tight junction biogenesis. As part of the mucosal immune response induced by commensal bacteria, enhances host's ability to resist pathogenic bacterial and fungal infections by promoting neutrophil recruitment and antimicrobial peptides release. In synergy with IL17F, mediates the production of antimicrobial beta-defensins DEFB1, DEFB103A, and DEFB104A by mucosal epithelial cells, limiting the entry of microbes through the epithelial barriers. Involved in antiviral host defense through various mechanisms. Enhances immunity against West Nile virus by promoting T cell cytotoxicity. May play a beneficial role in influenza A virus (H5N1) infection by enhancing B cell recruitment and immune response in the lung. Contributes to influenza A virus (H1N1) clearance by driving the differentiation of B-1a B cells, providing for production of virus-specific IgM antibodies at first line of host defense., [UniProtKB, UniProtKB]; This study provides evidence that IL-1beta combined with IL-17A promoted chronic inflammatory arthritis by activating the catabolic processes accompanied with the suppression of cartilage anabolism. These suggest that further applications, which suppress inflammatory enhancers, especially IL-17A, should be considered as a target for arthritis research and therapy. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0010557 positive regulation of macromolecule biosynthetic process;GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0002250 adaptive immune response;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q60I29-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q64L94-1", "uniprot_id": [ { "id": "PSME1_PIG", "url": "https://www.uniprot.org/uniprot/Q64L94", "type": "external" } ], "mass": 28617.0, "length": 249, "protein_name": "Proteasome activator complex subunit 1", "gene_name": "PSME1", "organism": "Pig", "refseq_name": "proteasome activator complex subunit 1", "refseq_ac": [ { "id": "NP_999469", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999469", "type": "external" } ], "gene_names_uniprotkb": "PSME1", "gene_names_refseq": "PSME1", "protein_names_uniprotkb": "Proteasome activator complex subunit 1; PA28alpha; PA28a; Proteasome activator 28 subunit alpha", "protein_names_refseq": "PA28alpha; PA28a; proteasome (prosome, macropain) activator subunit 1 (PA28 alpha); proteasome activator 28 alpha subunit; proteasome activator 28 subunit alpha; proteasome activator PA28 alpha subunit; proteasome activator complex subunit 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397572); (R-SSC-9907900)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15373739", "class_list": "", "function": "Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q863Z1", "ec_number_list": [], "go_molecular_function": "GO:0061133 endopeptidase activator activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0008537 proteasome activator complex", "go_biological_process": "GO:2000045 regulation of G1/S transition of mitotic cell cycle;GO:0061136 regulation of proteasomal protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q64L94-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q66RM2-1", "uniprot_id": [ { "id": "BI1_PIG", "url": "https://www.uniprot.org/uniprot/Q66RM2", "type": "external" } ], "mass": 26408.0, "length": 237, "protein_name": "Bax inhibitor 1", "gene_name": "TMBIM6", "organism": "Pig", "refseq_name": "bax inhibitor 1", "refseq_ac": [ { "id": "NP_001005348", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005348", "type": "external" } ], "gene_names_uniprotkb": "TMBIM6; TEGT", "gene_names_refseq": "BI-1; TEGT; TMBIM6", "protein_names_uniprotkb": "Bax inhibitor 1; BI-1; Testis-enhanced gene transcript protein; Transmembrane BAX inhibitor motif-containing protein 6", "protein_names_refseq": "Bax inhibitor-1; bax inhibitor 1; testis enhanced gene transcript; testis-enhanced gene transcript protein; transmembrane BAX inhibitor motif-containing protein 6", "tax_id": 9823, "disease": "", "pathway": " (ssc:396907)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Endoplasmic reticulum (ER)-resident protein that confers cellular protection as an anti-apoptotic protein by limiting multiple stress-inducing pathways surrounding the endoplasmic reticulum and mitochondria. Inhibits the activities of the key sensor for the endoplasmic reticulum unfolded protein response IRE1alpha/ERN1 both directly and by blocking BAX/BAK binding. Modulates ER calcium homeostasis by acting as a calcium-leak channel (By similarity). Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005262 calcium channel activity;GO:0060698 endoribonuclease inhibitor activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006915 apoptotic process;GO:0006914 autophagy;GO:2001234 negative regulation of apoptotic signaling pathway;GO:0034620 cellular response to unfolded protein", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q66RM2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q684M3-1", "uniprot_id": [ { "id": "S1PR5_PIG", "url": "https://www.uniprot.org/uniprot/Q684M3", "type": "external" } ], "mass": 41861.0, "length": 398, "protein_name": "Sphingosine 1-phosphate receptor 5", "gene_name": "S1PR5", "organism": "Pig", "refseq_name": "sphingosine 1-phosphate receptor 5", "refseq_ac": [ { "id": "NP_001116581", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116581", "type": "external" } ], "gene_names_uniprotkb": "S1PR5; EDG8", "gene_names_refseq": "EDG8; S1P5; S1PR5", "protein_names_uniprotkb": "Sphingosine 1-phosphate receptor 5; Endothelial differentiation G protein-coupled receptor 8; S1P receptor 5; S1P receptor Edg-8; S1P5; Sphingosine 1-phosphate receptor Edg-8", "protein_names_refseq": "S1P receptor 5; S1P receptor Edg-8; Sphingosine 1-phosphate receptor Edg-8; endothelial differentiation G-protein-coupled receptor 8; endothelial differentiation, sphingolipid G-protein-coupled receptor, 8; sphingosine 1-phosphate receptor 5", "tax_id": 9823, "disease": "", "pathway": " (ssc:100141401); (R-SSC-418594); (R-SSC-419408)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/O)alpha and G(12) subclass of heteromeric G proteins (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0038036 sphingosine-1-phosphate receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q684M3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000011001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q69DL0-1", "uniprot_id": [ { "id": "C1QA_PIG", "url": "https://www.uniprot.org/uniprot/Q69DL0", "type": "external" } ], "mass": 26483.0, "length": 247, "protein_name": "Complement C1q subcomponent subunit A", "gene_name": "C1QA", "organism": "Pig", "refseq_name": "complement C1q subcomponent subunit A precursor", "refseq_ac": [ { "id": "NP_001003924", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003924", "type": "external" } ], "gene_names_uniprotkb": "C1QA", "gene_names_refseq": "C1QA", "protein_names_uniprotkb": "Complement C1q subcomponent subunit A", "protein_names_refseq": "complement C1q subcomponent subunit A precursor; complement C1q subcomponent subunit A; complement C1qA", "tax_id": 9823, "disease": "", "pathway": " (ssc:445461)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Core component of the complement C1 complex, a multiprotein complex that initiates the classical pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. The classical complement pathway is initiated by the C1Q subcomplex of the C1 complex, which specifically binds IgG or IgM immunoglobulins complexed with antigens, forming antigen-antibody complexes on the surface of pathogens: C1QA, together with C1QB and C1QC, specifically recognizes and binds the Fc regions of IgG or IgM via its C1q domain. Immunoglobulin-binding activates the proenzyme C1R, which cleaves C1S, initiating the proteolytic cascade of the complement system. The C1Q subcomplex is activated by a hexamer of IgG complexed with antigens, while it is activated by a pentameric IgM. The C1Q subcomplex also recognizes and binds phosphatidylserine exposed on the surface of cells undergoing programmed cell death, possibly promoting activation of the complement system., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0009986 cell surface;GO:0005602 complement component C1 complex", "go_biological_process": "GO:0045087 innate immune response;GO:0006958 complement activation, classical pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q69DL0-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6ITT3-1", "uniprot_id": [ { "id": "MGT4C_PIG", "url": "https://www.uniprot.org/uniprot/Q6ITT3", "type": "external" } ], "mass": 56312.0, "length": 478, "protein_name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C", "gene_name": "MGAT4C", "organism": "Pig", "refseq_name": "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C", "refseq_ac": [ { "id": "NP_001001859", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001859", "type": "external" } ], "gene_names_uniprotkb": "MGAT4C", "gene_names_refseq": "HGNT-IV-H; MGAT4C", "protein_names_uniprotkb": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C; 2.4.1.145; GnT-IVc; N-acetylglucosaminyltransferase IVc; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc; UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc", "protein_names_refseq": "N-acetylglucosaminyltransferase IVc; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc; UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc; UDP-N-acetylglucosamine:a-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV-like protein; alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C; gnT-IVc; mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)", "tax_id": 9823, "disease": "", "pathway": " (ssc:414851); (R-SSC-975577)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "glycogene;glycosyltransferase", "function": "Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity) (By similarity)., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0008375 acetylglucosaminyltransferase activity;GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 3884, "hit_score": 0.1, "record_id": "Q6ITT3-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000010000.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6KEQ9-1", "uniprot_id": [ { "id": "PC11X_PIG", "url": "https://www.uniprot.org/uniprot/Q6KEQ9", "type": "external" } ], "mass": 123364.0, "length": 1117, "protein_name": "Protocadherin-11 X-linked", "gene_name": "PCDH11X", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PCDH11X; PCDH11; PCDHX", "gene_names_refseq": "", "protein_names_uniprotkb": "Protocadherin-11 X-linked; PCDH-X; Protocadherin on the X chromosome; Protocadherin-11", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "15112107", "class_list": "", "function": "Potential calcium-dependent cell-adhesion protein., [UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q6KEQ6;Q6KEQ8", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6KEQ9-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6PKU1-1", "uniprot_id": [ { "id": "SPI1_PIG", "url": "https://www.uniprot.org/uniprot/Q6PKU1", "type": "external" } ], "mass": 31093.0, "length": 270, "protein_name": "Transcription factor PU.1", "gene_name": "SPI1", "organism": "Pig", "refseq_name": "transcription factor PU.1", "refseq_ac": [ { "id": "NP_001001865", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001865", "type": "external" } ], "gene_names_uniprotkb": "SPI1", "gene_names_refseq": "PU.1; SPI1", "protein_names_uniprotkb": "Transcription factor PU.1", "protein_names_refseq": "spleen focus forming virus (SFFV) proviral integration oncogene spi1; transcription factor PU.1", "tax_id": 9823, "disease": "", "pathway": " (ssc:414912)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "25691151", "class_list": "", "function": "Antisense lncRNA blocking PU.1 translation promotes adipogenesis in porcine preadipocytes, [RefSeq, PubMed]; Pioneer transcription factor, which controls hematopoietic cell fate by decompacting stem cell heterochromatin and allowing other transcription factors to enter otherwise inaccessible genomic sites. Once in open chromatin, can directly control gene expression by binding genetic regulatory elements and can also more broadly influence transcription by recruiting transcription factors, such as interferon regulatory factors (IRFs), to otherwise inaccessible genomic regions (By similarity). Transcriptionally activates genes important for myeloid and lymphoid lineages, such as CSF1R (By similarity). Transcriptional activation from certain promoters, possibly containing low affinity binding sites, is achieved cooperatively with other transcription factors. FCER1A transactivation is achieved in cooperation with GATA1 (By similarity). May be particularly important for the pro- to pre-B cell transition. Binds (via the ETS domain) onto the purine-rich DNA core sequence 5'-GAGGAA-3', also known as the PU-box (By similarity). In vitro can bind RNA and interfere with pre-mRNA splicing (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0045815 transcription initiation-coupled chromatin remodeling;GO:0045579 positive regulation of B cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6PKU1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6Q7J2-1", "uniprot_id": [ { "id": "GDIB_PIG", "url": "https://www.uniprot.org/uniprot/Q6Q7J2", "type": "external" } ], "mass": 50268.0, "length": 445, "protein_name": "Rab GDP dissociation inhibitor beta", "gene_name": "GDI2", "organism": "Pig", "refseq_name": "rab GDP dissociation inhibitor beta", "refseq_ac": [ { "id": "NP_001001643", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001643", "type": "external" } ], "gene_names_uniprotkb": "GDI2", "gene_names_refseq": "GDI2", "protein_names_uniprotkb": "Rab GDP dissociation inhibitor beta; GDI-2; Guanosine diphosphate dissociation inhibitor 2; Rab GDI beta", "protein_names_refseq": "GDI-2; guanosine diphosphate dissociation inhibitor 2; rab GDI beta; rab GDP dissociation inhibitor beta", "tax_id": 9823, "disease": "", "pathway": " (ssc:414427)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15625692", "class_list": "", "function": "GDP-dissociation inhibitor preventing the GDP to GTP exchange of most Rab proteins. By keeping these small GTPases in their inactive GDP-bound form regulates intracellular membrane trafficking. Negatively regulates protein transport to the cilium and ciliogenesis through the inhibition of RAB8A., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005093 Rab GDP-dissociation inhibitor activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:1902018 negative regulation of cilium assembly;GO:0015031 protein transport;GO:0007264 small GTPase-mediated signal transduction;GO:0016192 vesicle-mediated transport;GO:1903565 negative regulation of protein localization to cilium", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6Q7J2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6Q7K0-1", "uniprot_id": [ { "id": "ASTER_PIG", "url": "https://www.uniprot.org/uniprot/Q6Q7K0", "type": "external" } ], "mass": 11942.0, "length": 106, "protein_name": "PAT complex subunit Asterix", "gene_name": "WDR83OS", "organism": "Pig", "refseq_name": "PAT complex subunit Asterix", "refseq_ac": [ { "id": "NP_001001645", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001645", "type": "external" } ], "gene_names_uniprotkb": "WDR83OS", "gene_names_refseq": "PAT-10; PAT10; WDR83OS", "protein_names_uniprotkb": "PAT complex subunit Asterix; PAT-10; PAT10; Protein WDR83OS homolog; Protein associated with the ER translocon of 10kDa", "protein_names_refseq": "CGI-140; PAT complex subunit Asterix; UPF0139 membrane protein C19orf56 homolog; protein Asterix; protein WDR83OS homolog; protein associated with the ER translocon of 10kDa", "tax_id": 9823, "disease": "", "pathway": " (ssc:414435)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15625692", "class_list": "", "function": "Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes. The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (By similarity). Within the MPT complex, the PAT subcomplex sequesters any highly polar regions in the transmembrane domains away from the non-polar membrane environment until they can be buried in the interior of the fully assembled protein. Within the PAT subcomplex, WDR83OS/Asterix binds to and redirects the substrate to a location behind the SEC61 complex (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0160064 multi-pass translocon complex", "go_biological_process": "GO:0045048 protein insertion into ER membrane;GO:0160063 multi-pass transmembrane protein insertion into ER membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6Q7K0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6QA76-1", "uniprot_id": [ { "id": "PDZ11_PIG", "url": "https://www.uniprot.org/uniprot/Q6QA76", "type": "external" } ], "mass": 16155.0, "length": 140, "protein_name": "PDZ domain-containing protein 11", "gene_name": "PDZD11", "organism": "Pig", "refseq_name": "PDZ domain-containing protein 11", "refseq_ac": [ { "id": "NP_001001630", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001630", "type": "external" } ], "gene_names_uniprotkb": "PDZD11; PDZK11", "gene_names_refseq": "PDZD11", "protein_names_uniprotkb": "PDZ domain-containing protein 11", "protein_names_refseq": "2700099C19-like protein; PDZ domain-containing protein 11", "tax_id": 9823, "disease": "", "pathway": " (ssc:414386); (R-SSC-196780); (R-SSC-199220); (R-SSC-425397); (R-SSC-6803544); (R-SSC-936837)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mediates docking of ADAM10 to zonula adherens by interacting with PLEKHA7 which is required for PLEKHA7 to interact with the ADAM10-binding protein TSPAN33., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005911 cell-cell junction;GO:0005912 adherens junction;GO:0016323 basolateral plasma membrane;GO:0046930 pore complex", "go_biological_process": "GO:0046931 pore complex assembly;GO:0007269 neurotransmitter secretion;GO:0048489 synaptic vesicle transport;GO:0008582 regulation of synaptic assembly at neuromuscular junction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q6QA76-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6QAP7-1", "uniprot_id": [ { "id": "RS17_PIG", "url": "https://www.uniprot.org/uniprot/Q6QAP7", "type": "external" } ], "mass": 15524.0, "length": 135, "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "RPS17", "organism": "Pig", "refseq_name": "small ribosomal subunit protein eS17", "refseq_ac": [ { "id": "NP_001001634", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001634", "type": "external" } ], "gene_names_uniprotkb": "RPS17", "gene_names_refseq": "RPS17", "protein_names_uniprotkb": "Small ribosomal subunit protein eS17; 40S ribosomal protein S17", "protein_names_refseq": "40S ribosomal protein S17; small ribosomal subunit protein eS17", "tax_id": 9823, "disease": "", "pathway": " (ssc:414392); (R-SSC-156827); (R-SSC-1799339); (R-SSC-72649); (R-SSC-72689); (R-SSC-72695); (R-SSC-72702); (R-SSC-72706); (R-SSC-975956); (R-SSC-975957); (R-SSC-9954714); (R-SSC-9954716)", "pathway_count": 12, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0045202 synapse;GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane;GO:0032040 small-subunit processome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q6QAP7-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6QAT0-1", "uniprot_id": [ { "id": "RL32_PIG", "url": "https://www.uniprot.org/uniprot/Q6QAT0", "type": "external" } ], "mass": 15860.0, "length": 135, "protein_name": "Large ribosomal subunit protein eL32", "gene_name": "RPL32", "organism": "Pig", "refseq_name": "large ribosomal subunit protein eL32", "refseq_ac": [ { "id": "NP_001001636", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001636", "type": "external" } ], "gene_names_uniprotkb": "RPL32", "gene_names_refseq": "RPL32", "protein_names_uniprotkb": "Large ribosomal subunit protein eL32; 60S ribosomal protein L32", "protein_names_refseq": "60S ribosomal protein L32; large ribosomal subunit protein eL32", "tax_id": 9823, "disease": "", "pathway": " (ssc:414419); (R-SSC-156827); (R-SSC-1799339); (R-SSC-6791226); (R-SSC-72689); (R-SSC-72706); (R-SSC-975956); (R-SSC-975957); (R-SSC-9954709); (R-SSC-9954714); (R-SSC-9954716)", "pathway_count": 11, "publication_count": 2, "publication_id_list": "21631284;8672129", "class_list": "", "function": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]; Data suggest the combination of three genes RPL32, RPS18, and H3F3A is the most suitable for accurate normalization., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q29280", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0045202 synapse;GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane;GO:0022625 cytosolic large ribosomal subunit;GO:0015934 large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q6QAT0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6UN27-1", "uniprot_id": [ { "id": "TSPO_PIG", "url": "https://www.uniprot.org/uniprot/Q6UN27", "type": "external" } ], "mass": 18609.0, "length": 169, "protein_name": "Translocator protein", "gene_name": "TSPO", "organism": "Pig", "refseq_name": "translocator protein", "refseq_ac": [ { "id": "NP_998918", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998918", "type": "external" } ], "gene_names_uniprotkb": "TSPO; BZRP", "gene_names_refseq": "BZRP; PBR; TSPO", "protein_names_uniprotkb": "Translocator protein; PBR; Peripheral-type benzodiazepine receptor", "protein_names_refseq": "peripheral benzodiazepine receptor; peripheral-type benzodiazepine receptor; translocator protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:396592)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "17019653;19386723", "class_list": "", "function": "Changes in TSPO expression in kidney regenerating tissue could be important for renal protection and maintenance of kidney function., [RefSeq, PubMed]; PBR mRNA was the more abundant detected form in pig tissues and in warm kidney that underwent ischemia suggesting functional implications of PBR during the renal repair process., [RefSeq, PubMed]; Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0006869 lipid transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q6UN27-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6WZ17-1", "uniprot_id": [ { "id": "NGB_PIG", "url": "https://www.uniprot.org/uniprot/Q6WZ17", "type": "external" } ], "mass": 16986.0, "length": 151, "protein_name": "Neuroglobin", "gene_name": "NGB", "organism": "Pig", "refseq_name": "neuroglobin", "refseq_ac": [ { "id": "NP_001001647", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001647", "type": "external" } ], "gene_names_uniprotkb": "NGB", "gene_names_refseq": "NGB", "protein_names_uniprotkb": "Neuroglobin; 1.7.-.-; Nitrite reductase", "protein_names_refseq": "neuroglobin; nitrite reductase", "tax_id": 9823, "disease": "", "pathway": " (ssc:414438); (R-SSC-8981607)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15804835;20705062", "class_list": "", "function": "Constitutive expression levels of neuroglobin in neonatal brain cells may explain mild neuronal injury after 60 min. of deep hypothermic circulatory arrest., [RefSeq, PubMed]; Monomeric globin with a bis-histidyl six-coordinate heme-iron atom through which it can bind dioxygen, carbon monoxide and nitric oxide. Could help transport oxygen and increase its availability to the metabolically active neuronal tissues, though its low quantity in tissues as well as its high affinity for dioxygen, which may limit its oxygen-releasing ability, argue against it. The ferrous/deoxygenated form exhibits a nitrite reductase activity and it could produce nitric oxide which in turn inhibits cellular respiration in response to hypoxia. In its ferrous/deoxygenated state, it may also exhibit GDI (Guanine nucleotide Dissociation Inhibitor) activity toward heterotrimeric G-alpha proteins, thereby regulating signal transduction to facilitate neuroprotective responses in the wake of hypoxia and associated oxidative stress., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6ZYE8", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0005092 GDP-dissociation inhibitor activity;GO:0019825 oxygen binding;GO:0005344 oxygen carrier activity", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0005829 cytosol", "go_biological_process": "GO:0001666 response to hypoxia;GO:0071456 cellular response to hypoxia;GO:0015671 oxygen transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q6WZ17-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q6YST0-1", "uniprot_id": [ { "id": "Q6YST0_PIG", "url": "https://www.uniprot.org/uniprot/Q6YST0", "type": "external" } ], "mass": 40989.0, "length": 354, "protein_name": "C-C motif chemokine receptor 1", "gene_name": "CCR1", "organism": "Pig", "refseq_name": "C-C chemokine receptor type 1", "refseq_ac": [ { "id": "NP_001001621", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001621", "type": "external" } ], "gene_names_uniprotkb": "CCR1", "gene_names_refseq": "CCR1", "protein_names_uniprotkb": "C-C motif chemokine receptor 1", "protein_names_refseq": "C-C chemokine receptor type 1; chemokine C-C motif receptor 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:414374); (R-SSC-380108); (R-SSC-418594)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "28694169;32543654", "class_list": "", "function": "CCL23-CCR1 signaling is important for endometrial development and establishment of pregnancy in pigs, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004435 phosphatidylinositol-4,5-bisphosphate phospholipase C activity;GO:0016493 C-C chemokine receptor activity;GO:0071791 chemokine (C-C motif) ligand 5 binding;GO:0035717 chemokine (C-C motif) ligand 7 binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0006955 immune response;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0007267 cell-cell signaling;GO:0010629 negative regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q6YST0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q711S8-1", "uniprot_id": [ { "id": "SPP24_PIG", "url": "https://www.uniprot.org/uniprot/Q711S8", "type": "external" } ], "mass": 23097.0, "length": 204, "protein_name": "Secreted phosphoprotein 24", "gene_name": "SPP2", "organism": "Pig", "refseq_name": "secreted phosphoprotein 24 precursor", "refseq_ac": [ { "id": "NP_998945", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998945", "type": "external" } ], "gene_names_uniprotkb": "SPP2; SPP24", "gene_names_refseq": "SPP2", "protein_names_uniprotkb": "Secreted phosphoprotein 24; Secreted phosphoprotein 2; Spp-24", "protein_names_refseq": "secreted phosphoprotein 24 precursor; secreted phosphoprotein 24; spp-24", "tax_id": 9823, "disease": "", "pathway": " (ssc:396669)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15062857", "class_list": "", "function": "Could coordinate an aspect of bone turnover., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0046849 bone remodeling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q711S8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q75ZH0-1", "uniprot_id": [ { "id": "CCRL2_PIG", "url": "https://www.uniprot.org/uniprot/Q75ZH0", "type": "external" } ], "mass": 40592.0, "length": 350, "protein_name": "Chemokine C-C motif receptor-like 2", "gene_name": "CCRL2", "organism": "Pig", "refseq_name": "chemokine C-C motif receptor-like 2", "refseq_ac": [ { "id": "NP_001001617", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001617", "type": "external" } ], "gene_names_uniprotkb": "CCRL2", "gene_names_refseq": "CCRL2", "protein_names_uniprotkb": "Chemokine C-C motif receptor-like 2", "protein_names_refseq": "chemokine C-C motif receptor-like 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:414370); (R-SSC-380108)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15777643", "class_list": "", "function": "Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in modulating chemokine-triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand to CMKLR1, a functional signaling receptor. Plays a critical role for the development of Th2 responses (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016493 C-C chemokine receptor activity;GO:0019957 C-C chemokine binding;GO:0048020 CCR chemokine receptor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0006955 immune response;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0019722 calcium-mediated signaling;GO:0060326 cell chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q75ZH0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q75ZP3-1", "uniprot_id": [ { "id": "IBP1_PIG", "url": "https://www.uniprot.org/uniprot/Q75ZP3", "type": "external" } ], "mass": 28331.0, "length": 262, "protein_name": "Insulin-like growth factor-binding protein 1", "gene_name": "IGFBP1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IGFBP1", "gene_names_refseq": "", "protein_names_uniprotkb": "Insulin-like growth factor-binding protein 1; IBP-1; IGF-binding protein 1; IGFBP-1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "15859522", "class_list": "", "function": "Multifunctional protein that plays a critical role in regulating the availability of IGFs such as IGF1 and IGF2 to their receptors and thereby regulates IGF-mediated cellular processes including cell migration, proliferation, differentiation or apoptosis in a cell-type specific manner. Also plays a positive role in cell migration by interacting with integrin ITGA5:ITGB1 through its RGD motif. Mechanistically, binding to integrins leads to activation of focal adhesion kinase/PTK2 and stimulation of the mitogen-activated protein kinase (MAPK) pathway (By similarity). Regulates cardiomyocyte apoptosis by suppressing HIF-1alpha/HIF1A degradation through ubiquitination (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031994 insulin-like growth factor I binding;GO:0031995 insulin-like growth factor II binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0043567 regulation of insulin-like growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q75ZP3-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q767K8-1", "uniprot_id": [ { "id": "RT18B_PIG", "url": "https://www.uniprot.org/uniprot/Q767K8", "type": "external" } ], "mass": 29178.0, "length": 258, "protein_name": "Small ribosomal subunit protein mS40", "gene_name": "MRPS18B", "organism": "Pig", "refseq_name": "small ribosomal subunit protein mS40", "refseq_ac": [ { "id": "NP_001116612", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116612", "type": "external" } ], "gene_names_uniprotkb": "MRPS18B", "gene_names_refseq": "MRPS18B", "protein_names_uniprotkb": "Small ribosomal subunit protein mS40; 28S ribosomal protein S18-2, mitochondrial; 28S ribosomal protein S18b, mitochondrial; MRP-S18-2; MRP-S18-b; Mrps18-b; S18mt-b", "protein_names_refseq": "28S ribosomal protein S18-2, mitochondrial; 28S ribosomal protein S18b, mitochondrial; MRP-S18-2; MRP-S18-b; S18mt-b; mitochondrial 28S ribosomal protein S18b; mitochondrial ribosomal protein S18-2; mrps18-b; small ribosomal subunit protein mS40", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144465); (R-SSC-5389840); (R-SSC-5419276); (R-SSC-9937383)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "14673549;25837512", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q767K8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q767L8-1", "uniprot_id": [ { "id": "MDC1_PIG", "url": "https://www.uniprot.org/uniprot/Q767L8", "type": "external" } ], "mass": 217917.0, "length": 2042, "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "organism": "Pig", "refseq_name": "mediator of DNA damage checkpoint protein 1", "refseq_ac": [ { "id": "NP_001116610", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116610", "type": "external" } ], "gene_names_uniprotkb": "MDC1", "gene_names_refseq": "MDC1", "protein_names_uniprotkb": "Mediator of DNA damage checkpoint protein 1", "protein_names_refseq": "mediator of DNA damage checkpoint protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144453)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "14673549", "class_list": "", "function": "Histone reader protein required for checkpoint-mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. Specifically recognizes and binds histone H2AX phosphorylated at 'Ser-139', a marker of DNA damage, serving as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage sites. Also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53/p53 and apoptosis. ATM and CHEK2 may also be activated independently by a parallel pathway mediated by TP53BP1. Required for chromosomal stability during mitosis by promoting recruitment of TOPBP1 to DNA double strand breaks (DSBs): TOPBP1 forms filamentous assemblies that bridge MDC1 and tether broken chromosomes during mitosis. Required for the repair of DSBs via homologous recombination by promoting recruitment of NBN component of the MRN complex to DSBs., [UniProtKB, UniProtKB]", "predicted_glycosites": 9, "predicted_n_glycosites": 0, "predicted_o_glycosites": 9, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 54, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "Q767K4", "ec_number_list": [], "go_molecular_function": "GO:0140463 chromatin-protein adaptor activity;GO:0140566 histone reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0035861 site of double-strand break;GO:0005694 chromosome", "go_biological_process": "GO:1990166 protein localization to site of double-strand break;GO:0000076 DNA replication checkpoint signaling;GO:0006281 DNA repair;GO:0006974 DNA damage response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q767L8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q767M3-1", "uniprot_id": [ { "id": "SYVM_PIG", "url": "https://www.uniprot.org/uniprot/Q767M3", "type": "external" } ], "mass": 118288.0, "length": 1062, "protein_name": "Valine--tRNA ligase, mitochondrial", "gene_name": "VARS2", "organism": "Pig", "refseq_name": "valine--tRNA ligase, mitochondrial precursor", "refseq_ac": [ { "id": "NP_001116686", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116686", "type": "external" } ], "gene_names_uniprotkb": "VARS2", "gene_names_refseq": "VARS2", "protein_names_uniprotkb": "Valine--tRNA ligase, mitochondrial; 6.1.1.9; ValRS; Valyl-tRNA synthetase", "protein_names_refseq": "valRS; valine--tRNA ligase, mitochondrial precursor; valine--tRNA ligase, mitochondrial; valyl-tRNA synthetase, mitochondrial", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144457)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "14673549", "class_list": "", "function": "Catalyzes the attachment of valine to tRNA(Val) in a two-step reaction: valine is first activated by ATP to form Val-AMP and then transferred to the acceptor end of tRNA(Val)., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0002161 aminoacyl-tRNA deacylase activity;GO:0004832 valine-tRNA ligase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006438 valyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q767M3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q76LU6-1", "uniprot_id": [ { "id": "IL21_PIG", "url": "https://www.uniprot.org/uniprot/Q76LU6", "type": "external" } ], "mass": 17575.0, "length": 152, "protein_name": "Interleukin-21", "gene_name": "IL21", "organism": "Pig", "refseq_name": "interleukin-21 precursor", "refseq_ac": [ { "id": "NP_999580", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999580", "type": "external" } ], "gene_names_uniprotkb": "IL21", "gene_names_refseq": "IL21", "protein_names_uniprotkb": "Interleukin-21; IL-21", "protein_names_refseq": "IL-21; Interleukin-21; interleukin-21 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:403123)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15107555", "class_list": "", "function": "Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity (PubMed:15107555). Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (By similarity). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation (By similarity)., [UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0005126 cytokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006952 defense response;GO:0001819 positive regulation of cytokine production;GO:0002314 germinal center B cell differentiation;GO:0098586 cellular response to virus;GO:0045954 positive regulation of natural killer cell mediated cytotoxicity", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q76LU6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7YQE5-1", "uniprot_id": [ { "id": "PLET1_PIG", "url": "https://www.uniprot.org/uniprot/Q7YQE5", "type": "external" } ], "mass": 23255.0, "length": 210, "protein_name": "Placenta-expressed transcript 1 protein", "gene_name": "PLET1", "organism": "Pig", "refseq_name": "placenta-expressed transcript 1 protein precursor", "refseq_ac": [ { "id": "NP_998909", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998909", "type": "external" } ], "gene_names_uniprotkb": "PLET1", "gene_names_refseq": "PLET1; PLET", "protein_names_uniprotkb": "Placenta-expressed transcript 1 protein", "protein_names_refseq": "Placenta-expressed transcript 1 protein; placenta expressed transcript protein; placenta-expressed transcript 1 protein precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:396570); (R-SSC-163125)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15203209", "class_list": "", "function": "Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0030154 cell differentiation;GO:0030335 positive regulation of cell migration;GO:0001953 negative regulation of cell-matrix adhesion;GO:0035313 wound healing, spreading of epidermal cells", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q7YQE5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7YR76-1", "uniprot_id": [ { "id": "MYCD_PIG", "url": "https://www.uniprot.org/uniprot/Q7YR76", "type": "external" } ], "mass": 100652.0, "length": 933, "protein_name": "Myocardin", "gene_name": "MYOCD", "organism": "Pig", "refseq_name": "myocardin", "refseq_ac": [ { "id": "NP_998910", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998910", "type": "external" } ], "gene_names_uniprotkb": "MYOCD", "gene_names_refseq": "MYOCD", "protein_names_uniprotkb": "Myocardin", "protein_names_refseq": "myocardin", "tax_id": 9823, "disease": "", "pathway": " (ssc:396571)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12920479;19247948;19574550;21792927;22028870", "class_list": "", "function": "A moderate inhibition (e.g., normalization) of the activated MYOCD signaling in the diseased heart may be promising from a therapeutic point of view, [RefSeq, PubMed]; Data show that forced myocd-A expression in the LVFW caused abnormal ECG., [RefSeq, PubMed]; MYOCD DeltaExon 11 may participate in modulating smooth muscle cell phenotype, potentially acting as a dominant-negative repressor of contraction-related genes., [RefSeq, PubMed]; Smooth muscle cells (SM) and cardiac muscle cells-specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes. Plays a crucial role in cardiogenesis, urinary bladder development, and differentiation of the smooth muscle cell lineage (myogenesis) (By similarity). Positively regulates the transcription of genes involved in vascular smooth muscle contraction (By similarity)., [UniProtKB, UniProtKB]; Thrombin stimulates swine smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1, RhoA, and myocardin., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045815 transcription initiation-coupled chromatin remodeling;GO:0051145 smooth muscle cell differentiation;GO:0055007 cardiac muscle cell differentiation;GO:0051147 regulation of muscle cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q7YR76-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7YRN2-1", "uniprot_id": [ { "id": "CD3E_PIG", "url": "https://www.uniprot.org/uniprot/Q7YRN2", "type": "external" } ], "mass": 22198.0, "length": 196, "protein_name": "T-cell surface glycoprotein CD3 epsilon chain", "gene_name": "CD3E", "organism": "Pig", "refseq_name": "T-cell surface glycoprotein CD3 epsilon chain precursor", "refseq_ac": [ { "id": "NP_999392", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999392", "type": "external" } ], "gene_names_uniprotkb": "CD3E", "gene_names_refseq": "CD3E; CD3", "protein_names_uniprotkb": "T-cell surface glycoprotein CD3 epsilon chain", "protein_names_refseq": "CD3 epsilon subunit; CD3e molecule; T-cell surface glycoprotein CD3 epsilon chain precursor; T-cell surface glycoprotein CD3 epsilon chain", "tax_id": 9823, "disease": "", "pathway": " (ssc:397455)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22672968", "class_list": "", "function": "Expressed and refolded porcine CD3 ectodomain molecules include CD3epsilon, CD3gamma, CD3delta, CD3epsilongamma heterodimer, CD3epsilondelta heterodimer, CD3epsilongamma single-chain fusion protein and CD3epsilondelta single-chain fusion protein, [RefSeq, PubMed]; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD247/CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways. CD3E ITAM phosphorylation creates docking sites for the protein kinase ZAP70 leading to ZAP70 phosphorylation and its conversion into a catalytically active enzyme. In addition of this role of signal transduction in T-cell activation, CD3E plays an essential role in correct T-cell development (By similarity). Also participates in internalization and cell surface down-regulation of TCR-CD3 complexes via endocytosis sequences present in CD3E cytosolic region (By similarity). In addition to its role as a TCR coreceptor, it serves as a receptor for ITPRIPL1 (By similarity). Ligand recognition inhibits T-cell activation by promoting interaction with NCK1, which prevents CD3E-ZAP70 interaction and blocks the ERK-NFkB signaling cascade and calcium influx (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0042105 alpha-beta T cell receptor complex", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0010628 positive regulation of gene expression;GO:0050852 T cell receptor signaling pathway;GO:0002250 adaptive immune response;GO:0009966 regulation of signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q7YRN2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q7YS91-1", "uniprot_id": [ { "id": "FAKD4_PIG", "url": "https://www.uniprot.org/uniprot/Q7YS91", "type": "external" } ], "mass": 71220.0, "length": 632, "protein_name": "FAST kinase domain-containing protein 4", "gene_name": "TBRG4", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TBRG4; CPR2", "gene_names_refseq": "", "protein_names_uniprotkb": "FAST kinase domain-containing protein 4; Cell cycle progression protein 2; Protein TBRG4; Transforming growth factor beta regulator 4", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "12759187", "class_list": "", "function": "Plays a role in processing of mitochondrial RNA precursors and in stabilization of a subset of mature mitochondrial RNA species, such as MT-CO1, MT-CO2, MT-CYB, MT-CO3, MT-ND3, MT-ND5 and MT-ATP8/6. May play a role in cell cycle progression., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7YS90", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0035770 ribonucleoprotein granule", "go_biological_process": "GO:0016071 mRNA metabolic process;GO:0000963 mitochondrial RNA processing;GO:0044528 regulation of mitochondrial mRNA stability;GO:0090615 mitochondrial mRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q7YS91-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q862B1-1", "uniprot_id": [ { "id": "CRSP1_PIG", "url": "https://www.uniprot.org/uniprot/Q862B1", "type": "external" } ], "mass": 14240.0, "length": 126, "protein_name": "Calcitonin receptor-stimulating peptide 1", "gene_name": "CRSP1", "organism": "Pig", "refseq_name": "calcitonin receptor-stimulating peptide 1 precursor", "refseq_ac": [ { "id": "NP_998907", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998907", "type": "external" } ], "gene_names_uniprotkb": "CRSP1; CRSP", "gene_names_refseq": "CALCB; CRSP-1; CRSP1; CRSP", "protein_names_uniprotkb": "Calcitonin receptor-stimulating peptide 1; CRSP-1", "protein_names_refseq": "Calcitonin receptor-stimulating peptide 1; calcitonin receptor-stimulating peptide 1 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:396563)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12556539;15781234;18544925", "class_list": "", "function": "CRSP-1 is considered to be a new regulator for the urinary ion excretion and renal epithelial cell growth, [RefSeq, PubMed]; CRSP1 and CRSP2 have almost identical sequences whereas CRSP3 retains less similarity with the above genes., [RefSeq, PubMed]; Stimulates cAMP production in porcine kidney cell line LLC-PK1 via the calcitonin receptor (CT) but not via the CT-like (CL) receptor., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031716 calcitonin receptor binding;GO:0005179 hormone activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0051480 regulation of cytosolic calcium ion concentration", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q862B1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q863Y7-1", "uniprot_id": [ { "id": "S52A2_PIG", "url": "https://www.uniprot.org/uniprot/Q863Y7", "type": "external" } ], "mass": 45828.0, "length": 446, "protein_name": "Solute carrier family 52, riboflavin transporter, member 2", "gene_name": "SLC52A2", "organism": "Pig", "refseq_name": "solute carrier family 52, riboflavin transporter, member 2", "refseq_ac": [ { "id": "NP_001004033", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004033", "type": "external" } ], "gene_names_uniprotkb": "SLC52A2; GPR172B; RFT1", "gene_names_refseq": "GPR172B; POPAR; SLC52A2", "protein_names_uniprotkb": "Solute carrier family 52, riboflavin transporter, member 2; Endogenous retrovirus A receptor; Protein GPR172B; Riboflavin transporter 1", "protein_names_refseq": "PERV-A receptor; endogenous retrovirus A receptor; riboflavin transporter 1; solute carrier family 52, riboflavin transporter, member 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:445519)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12740431", "class_list": "", "function": "(Microbial infection) In case of infection by porcine endogenous retrovirus (PERV-A), acts as a cell receptor to retroviral envelopes., [UniProtKB, PubMed]; Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism. May also act as a receptor for 4-hydroxybutyrate., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001618 virus receptor activity;GO:0032217 riboflavin transmembrane transporter activity;GO:0062124 4-hydroxybutyrate receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0032218 riboflavin transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q863Y7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q863Z0-1", "uniprot_id": [ { "id": "PSME2_PIG", "url": "https://www.uniprot.org/uniprot/Q863Z0", "type": "external" } ], "mass": 27296.0, "length": 239, "protein_name": "Proteasome activator complex subunit 2", "gene_name": "PSME2", "organism": "Pig", "refseq_name": "proteasome activator complex subunit 2", "refseq_ac": [ { "id": "NP_999444", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999444", "type": "external" } ], "gene_names_uniprotkb": "PSME2", "gene_names_refseq": "PSME2", "protein_names_uniprotkb": "Proteasome activator complex subunit 2; PA28beta; PA28b; Proteasome activator 28 subunit beta", "protein_names_refseq": "PA28 beta subunit; PA28beta; PA28b; proteasome (prosome, macropain) activator subunit 2 (PA28 beta); proteasome activator 28 beta subunit; proteasome activator 28 subunit beta; proteasome activator complex subunit 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:397522)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15373739", "class_list": "", "function": "Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0061133 endopeptidase activator activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0008537 proteasome activator complex", "go_biological_process": "GO:2000045 regulation of G1/S transition of mitotic cell cycle;GO:0061136 regulation of proteasomal protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q863Z0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q864U8-1", "uniprot_id": [ { "id": "B3GN5_PIG", "url": "https://www.uniprot.org/uniprot/Q864U8", "type": "external" } ], "mass": 43971.0, "length": 377, "protein_name": "Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase", "gene_name": "B3GNT5", "organism": "Pig", "refseq_name": "lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase", "refseq_ac": [ { "id": "NP_999492", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999492", "type": "external" } ], "gene_names_uniprotkb": "B3GNT5", "gene_names_refseq": "B3GNT5", "protein_names_uniprotkb": "Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase; 2.4.1.206; BGnT-5; Beta-1,3-Gn-T5; Beta-1,3-N-acetylglucosaminyltransferase 5; Beta3Gn-T5; Lactotriaosylceramide synthase; Lc(3)Cer synthase; Lc3 synthase; UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5", "protein_names_refseq": "BGnT-5; UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5; beta-1,3-Gn-T5; beta-1,3-N-acetylglucosaminyltransferase 5; beta3Gn-T5; lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase; lactotriaosylceramide synthase; lc(3)Cer synthase; lc3 synthase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397599); (R-SSC-913709); (R-SSC-9840309)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "16130451;21956797", "class_list": "glycogene;glycosyltransferase", "function": "Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development., [UniProtKB, UniProtKB]; None of the B3GNT5 polymorphisms and haplotypes was associated with susceptibility to enterotoxigenic Escherichia coli infections., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016757 glycosyltransferase activity;GO:0047256 lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0030148 sphingolipid biosynthetic process;GO:0007417 central nervous system development", "synthesized_glycan_count": 545, "hit_score": 0.3, "record_id": "Q864U8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010000.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q865K8-1", "uniprot_id": [ { "id": "PAQR7_PIG", "url": "https://www.uniprot.org/uniprot/Q865K8", "type": "external" } ], "mass": 39995.0, "length": 350, "protein_name": "Membrane progestin receptor alpha", "gene_name": "PAQR7", "organism": "Pig", "refseq_name": "membrane progestin receptor alpha", "refseq_ac": [ { "id": "NP_998904", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998904", "type": "external" } ], "gene_names_uniprotkb": "PAQR7; MRPA", "gene_names_refseq": "PAQR7; mSR", "protein_names_uniprotkb": "Membrane progestin receptor alpha; Membrane progesterone P4 receptor alpha; Membrane progesterone receptor alpha; Progesterone and adipoQ receptor family member 7; Progestin and adipoQ receptor family member 7; Progestin and adipoQ receptor family member VII; mPR alpha", "protein_names_refseq": "mPR alpha; membrane progesterone P4 receptor alpha; membrane progesterone receptor alpha; membrane progestin receptor alpha; progesterone and adipoQ receptor family member 7; progestin and adipoQ receptor family member VII; putative membrane steroid receptor", "tax_id": 9823, "disease": "", "pathway": " (ssc:396558)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12601167", "class_list": "", "function": "Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(i) mediated pathway. May be involved in oocyte maturation. Involved in neurosteroid inhibition of apoptosis. Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003707 nuclear steroid receptor activity;GO:0005496 steroid binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0048545 response to steroid hormone;GO:0048477 oogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q865K8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q865U8-1", "uniprot_id": [ { "id": "ANKR1_PIG", "url": "https://www.uniprot.org/uniprot/Q865U8", "type": "external" } ], "mass": 36126.0, "length": 319, "protein_name": "Ankyrin repeat domain-containing protein 1", "gene_name": "ANKRD1", "organism": "Pig", "refseq_name": "ankyrin repeat domain-containing protein 1", "refseq_ac": [ { "id": "NP_999087", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999087", "type": "external" } ], "gene_names_uniprotkb": "ANKRD1; CARP", "gene_names_refseq": "ANKRD1; CARP", "protein_names_uniprotkb": "Ankyrin repeat domain-containing protein 1; Cardiac ankyrin repeat protein", "protein_names_refseq": "ankyrin repeat domain-containing protein 1; cardiac ankyrin repeat protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:396959)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "14984723;15698842;19597856;21500110", "class_list": "", "function": "CAPZB, ANKRD1, and CTBP2 are promoted as candidate genes for meat quality that provide a link between signal pathways., [RefSeq, PubMed]; Endogenous ANKRD1 and calsequestrin are co-enriched in piglet cardiac Purkinje cells, [RefSeq, PubMed]; Expression analysis in porcine satellite cells showed that CARP and ANKRD2 were induced in differentiated porcine satellite cells, suggesting a role of them in myogenic differentiation., [RefSeq, PubMed]; May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0031432 titin binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q865U8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q865W2-1", "uniprot_id": [ { "id": "TRI50_PIG", "url": "https://www.uniprot.org/uniprot/Q865W2", "type": "external" } ], "mass": 54776.0, "length": 486, "protein_name": "E3 ubiquitin-protein ligase TRIM50", "gene_name": "TRIM50", "organism": "Pig", "refseq_name": "E3 ubiquitin-protein ligase TRIM50", "refseq_ac": [ { "id": "NP_999351", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999351", "type": "external" } ], "gene_names_uniprotkb": "TRIM50", "gene_names_refseq": "TRIM50A; TRIM50", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TRIM50; 2.3.2.27; RING-type E3 ubiquitin transferase TRIM50; Tripartite motif-containing protein 50", "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM50; RING-type E3 ubiquitin transferase TRIM50; tripartite motif protein 50; tripartite motif-containing protein 50", "tax_id": 9823, "disease": "", "pathway": " (ssc:397383)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "E3 ubiquitin-protein ligase that ubiquitinates Beclin-1/BECN1 in a 'Lys-63'-dependent manner enhancing its binding to ULK1. In turn, promotes starvation-induced autophagy activation. Also interacts with p62/SQSTM1 protein and thereby induces the formation and the autophagy clearance of aggresome-associated polyubiquitinated proteins through HDAC6 interaction. Also promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization independent of its E3 ligase function (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q865W2-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q866X6-1", "uniprot_id": [ { "id": "CAH11_PIG", "url": "https://www.uniprot.org/uniprot/Q866X6", "type": "external" } ], "mass": 36395.0, "length": 331, "protein_name": "Carbonic anhydrase-related protein 11", "gene_name": "CA11", "organism": "Pig", "refseq_name": "carbonic anhydrase-related protein 11 precursor", "refseq_ac": [ { "id": "NP_001004038", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004038", "type": "external" } ], "gene_names_uniprotkb": "CA11", "gene_names_refseq": "CA11; CAR-XI", "protein_names_uniprotkb": "Carbonic anhydrase-related protein 11; CA-RP XI; CA-XI; CARP XI", "protein_names_refseq": "CA-RP XI; CA-XI; CARP XI; carbonic anhydrase-related XI protein; carbonic anhydrase-related protein 11 precursor; carbonic anhydrase-related protein 11", "tax_id": 9823, "disease": "", "pathway": " (ssc:445526)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Does not have a catalytic activity., [UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016836 hydro-lyase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0016323 basolateral plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q866X6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8HXL3-1", "uniprot_id": [ { "id": "WDR62_PIG", "url": "https://www.uniprot.org/uniprot/Q8HXL3", "type": "external" } ], "mass": 168899.0, "length": 1541, "protein_name": "WD repeat-containing protein 62", "gene_name": "WDR62", "organism": "Pig", "refseq_name": "WD repeat-containing protein 62", "refseq_ac": [ { "id": "NP_001121933", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121933", "type": "external" } ], "gene_names_uniprotkb": "WDR62", "gene_names_refseq": "WDR62", "protein_names_uniprotkb": "WD repeat-containing protein 62", "protein_names_refseq": "WD repeat-containing protein 62", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144885)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "11856879", "class_list": "", "function": "Required for cerebral cortical development. Plays a role in neuronal proliferation and migration (By similarity). Plays a role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and CEP63 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005814 centriole;GO:0034451 centriolar satellite", "go_biological_process": "GO:0021987 cerebral cortex development;GO:0022008 neurogenesis;GO:0046605 regulation of centrosome cycle;GO:0007052 mitotic spindle organization;GO:0007099 centriole replication", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8HXL3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8HXW0-1", "uniprot_id": [ { "id": "GGLO_PIG", "url": "https://www.uniprot.org/uniprot/Q8HXW0", "type": "external" } ], "mass": 50352.0, "length": 440, "protein_name": "L-gulonolactone oxidase", "gene_name": "GULO", "organism": "Pig", "refseq_name": "L-gulonolactone oxidase", "refseq_ac": [ { "id": "NP_001123420", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001123420", "type": "external" } ], "gene_names_uniprotkb": "GULO", "gene_names_refseq": "GULO", "protein_names_uniprotkb": "L-gulonolactone oxidase; 1.1.3.8; GLO; L-gulono-gamma-lactone oxidase; LGO", "protein_names_refseq": "GLO; L-gulono-gamma-lactone oxidase; L-gulonolactone oxidase; LGO", "tax_id": 9823, "disease": "", "pathway": " (ssc:396759)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15112110;32543654", "class_list": "", "function": "Oxidizes L-gulono-1,4-lactone to hydrogen peroxide and L-xylo-hexulonolactone which spontaneously isomerizes to L-ascorbate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9N1U4", "ec_number_list": [], "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0071949 FAD binding;GO:0016491 oxidoreductase activity;GO:0003885 D-arabinono-1,4-lactone oxidase activity;GO:0050105 L-gulonolactone oxidase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0019853 L-ascorbic acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8HXW0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8HY46-1", "uniprot_id": [ { "id": "CPT1B_PIG", "url": "https://www.uniprot.org/uniprot/Q8HY46", "type": "external" } ], "mass": 88230.0, "length": 772, "protein_name": "Carnitine O-palmitoyltransferase 1, muscle isoform", "gene_name": "CPT1B", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CPT1B", "gene_names_refseq": "", "protein_names_uniprotkb": "Carnitine O-palmitoyltransferase 1, muscle isoform; 2.3.1.21; CPT I; CPT1-M; CPTI-M; Carnitine O-palmitoyltransferase I, muscle isoform; Carnitine palmitoyltransferase 1B", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004095 carnitine O-palmitoyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0006635 fatty acid beta-oxidation;GO:0015909 long-chain fatty acid transport;GO:0009437 carnitine metabolic process;GO:0009637 response to blue light", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q8HY46-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8HYA9-1", "uniprot_id": [ { "id": "GKN1_PIG", "url": "https://www.uniprot.org/uniprot/Q8HYA9", "type": "external" } ], "mass": 20104.0, "length": 185, "protein_name": "Gastrokine-1", "gene_name": "GKN1", "organism": "Pig", "refseq_name": "gastrokine-1 precursor", "refseq_ac": [ { "id": "NP_001182708", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182708", "type": "external" } ], "gene_names_uniprotkb": "GKN1; AMP18", "gene_names_refseq": "AMP-18; AMP18; GKN1", "protein_names_uniprotkb": "Gastrokine-1; 18 kDa antrum mucosa protein; AMP-18", "protein_names_refseq": "18 kDa antrum mucosa protein; gastrokine-1 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100502561)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12851218", "class_list": "", "function": "Has mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0042127 regulation of cell population proliferation;GO:0051781 positive regulation of cell division", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8HYA9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8HZJ6-1", "uniprot_id": [ { "id": "SDC4_PIG", "url": "https://www.uniprot.org/uniprot/Q8HZJ6", "type": "external" } ], "mass": 22081.0, "length": 202, "protein_name": "Syndecan-4", "gene_name": "SDC4", "organism": "Pig", "refseq_name": "syndecan-4 precursor", "refseq_ac": [ { "id": "NP_999449", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999449", "type": "external" } ], "gene_names_uniprotkb": "SDC4", "gene_names_refseq": "SDC4; Syndecan-4", "protein_names_uniprotkb": "Syndecan-4; SYND4", "protein_names_refseq": "SYND4; syndecan-4 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397528); (R-SSC-1971475); (R-SSC-2022928); (R-SSC-2024096); (R-SSC-3000170); (R-SSC-975634); (R-SSC-9769735); (R-SSC-9769739)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "27208778", "class_list": "", "function": "Cell surface proteoglycan which regulates exosome biogenesis in concert with SDCBP and PDCD6IP., [UniProtKB, UniProtKB]; Syndecan-4 mediates porcine respiratory and reproductive syndrome virus entry by interacting with EGFR., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0009986 cell surface;GO:0016020 membrane", "go_biological_process": "GO:0016477 cell migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8HZJ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8HZN9-1", "uniprot_id": [ { "id": "BKRB1_PIG", "url": "https://www.uniprot.org/uniprot/Q8HZN9", "type": "external" } ], "mass": 40146.0, "length": 353, "protein_name": "B1 bradykinin receptor", "gene_name": "BDKRB1", "organism": "Pig", "refseq_name": "B1 bradykinin receptor", "refseq_ac": [ { "id": "NP_001106535", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106535", "type": "external" } ], "gene_names_uniprotkb": "BDKRB1", "gene_names_refseq": "BDKRB1", "protein_names_uniprotkb": "B1 bradykinin receptor; B1R; BK-1 receptor", "protein_names_refseq": "B1 bradykinin receptor; B1R; BK-1 receptor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100127469)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "25258294", "class_list": "", "function": "B1 receptors are coupled to COX2 in causing endothelium-independent contractions in endotoxin-treated pig coronary arteries, [RefSeq, PubMed]; This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004947 bradykinin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0007186 G protein-coupled receptor signaling pathway;GO:0009612 response to mechanical stimulus;GO:0019371 cyclooxygenase pathway;GO:0060085 smooth muscle relaxation of the bladder outlet", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8HZN9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MI35-1", "uniprot_id": [ { "id": "NPW_PIG", "url": "https://www.uniprot.org/uniprot/Q8MI35", "type": "external" } ], "mass": 16347.0, "length": 152, "protein_name": "Neuropeptide W", "gene_name": "NPW", "organism": "Pig", "refseq_name": "neuropeptide W precursor", "refseq_ac": [ { "id": "NP_998951", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998951", "type": "external" } ], "gene_names_uniprotkb": "NPW; PPL8", "gene_names_refseq": "NPW; PPL8; PREPRO-NPW", "protein_names_uniprotkb": "Neuropeptide W; L8C; L8; PPL8; Preproprotein L8", "protein_names_refseq": "neuropeptide W precursor; prepro-neuropeptide W polypeptide; preproprotein L8", "tax_id": 9823, "disease": "", "pathway": " (ssc:396680); (R-SSC-375276); (R-SSC-418594)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "12130646", "class_list": "", "function": "Plays a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland. Stimulates water drinking and food intake. May play a role in the hypothalamic response to stress (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001664 G protein-coupled receptor binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007218 neuropeptide signaling pathway;GO:0007631 feeding behavior", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8MI35-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MI69-1", "uniprot_id": [ { "id": "WFDC2_PIG", "url": "https://www.uniprot.org/uniprot/Q8MI69", "type": "external" } ], "mass": 12756.0, "length": 123, "protein_name": "WAP four-disulfide core domain protein 2", "gene_name": "WFDC2", "organism": "Pig", "refseq_name": "WAP four-disulfide core domain protein 2 precursor", "refseq_ac": [ { "id": "NP_999112", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999112", "type": "external" } ], "gene_names_uniprotkb": "WFDC2", "gene_names_refseq": "E4; WFDC2", "protein_names_uniprotkb": "WAP four-disulfide core domain protein 2; Epididymal secretory protein E4", "protein_names_refseq": "Epididymal secretory protein E4; WAP four-disulfide core domain protein 2 precursor; WAP four-disulfide core domain protein 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:396987)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12654021", "class_list": "", "function": "Plays a critical role in lung development (By similarity). Required for terminal differentiation of bronchiole club cells (By similarity). Required for development of airway barrier mechanisms, such as lamellar body formation in type II alveolar epithelial cells and cilia formation on ciliated epithelial cells following initiation of respiration at birth (By similarity). Required for type I alveolar epithelial cell and vascular endothelial development in the lungs, thereby mediating blood-air barrier exchange (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity;GO:0019828 aspartic-type endopeptidase inhibitor activity;GO:0004869 cysteine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:1901248 positive regulation of lung ciliated cell differentiation;GO:0019731 antibacterial humoral response;GO:0045087 innate immune response;GO:0060426 lung vasculature development;GO:0060486 club cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8MI69-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MIA3-1", "uniprot_id": [ { "id": "S35A4_PIG", "url": "https://www.uniprot.org/uniprot/Q8MIA3", "type": "external" } ], "mass": 34225.0, "length": 324, "protein_name": "Probable UDP-sugar transporter protein SLC35A4", "gene_name": "SLC35A4", "organism": "Pig", "refseq_name": "probable UDP-sugar transporter protein SLC35A4", "refseq_ac": [ { "id": "NP_999116", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999116", "type": "external" } ], "gene_names_uniprotkb": "SLC35A4; NST", "gene_names_refseq": "NST; SLC35A4", "protein_names_uniprotkb": "Probable UDP-sugar transporter protein SLC35A4; Nucleotide sugar transporter; Solute carrier family 35 member A4", "protein_names_refseq": "nucleotide sugar transporter-like; probable UDP-sugar transporter protein SLC35A4; putative nucleotide sugar transporter", "tax_id": 9823, "disease": "", "pathway": " (ssc:396994); (R-SSC-9939291)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "12770764", "class_list": "", "function": "Mediates the transport of CDP-ribitol (By similarity). Does not exhibit CMP-sialic acid, UDP-galactose and UDP-N-acetylglucosamine transport activity (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8MIA3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MIK9-1", "uniprot_id": [ { "id": "PP14B_PIG", "url": "https://www.uniprot.org/uniprot/Q8MIK9", "type": "external" } ], "mass": 15911.0, "length": 147, "protein_name": "Protein phosphatase 1 regulatory subunit 14B", "gene_name": "PPP1R14B", "organism": "Pig", "refseq_name": "protein phosphatase 1 regulatory subunit 14B", "refseq_ac": [ { "id": "NP_999280", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999280", "type": "external" } ], "gene_names_uniprotkb": "PPP1R14B; PHI1", "gene_names_refseq": "PHI-1; PHI1; PPP1R14B; pPHI-1", "protein_names_uniprotkb": "Protein phosphatase 1 regulatory subunit 14B; PHI-1; Phosphatase holoenzyme inhibitor 1; Ubiquitous PKC-potentiated PP1 inhibitor", "protein_names_refseq": "phosphatase holoenzyme inhibitor 1; protein phosphatase 1 regulatory subunit 14B; ubiquitous PKC-potentiated PP1 inhibitor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397205)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12974676", "class_list": "", "function": "Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004865 protein serine/threonine phosphatase inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8MIK9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MIQ9-1", "uniprot_id": [ { "id": "P_PIG", "url": "https://www.uniprot.org/uniprot/Q8MIQ9", "type": "external" } ], "mass": 93185.0, "length": 845, "protein_name": "P protein", "gene_name": "Oca2", "organism": "Pig", "refseq_name": "P protein", "refseq_ac": [ { "id": "NP_999259", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999259", "type": "external" } ], "gene_names_uniprotkb": "Oca2; P", "gene_names_refseq": "OCA2", "protein_names_uniprotkb": "P protein; Melanocyte-specific transporter protein; Pink-eyed dilution protein homolog", "protein_names_refseq": "P protein; melanocyte-specific transporter protein; oculocutaneous albinism II (pink-eye dilution homolog, mouse); pink eye dilution; pink-eyed dilution protein homolog", "tax_id": 9823, "disease": "", "pathway": " (ssc:397171)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12354157", "class_list": "", "function": "Contributes to a melanosome-specific anion (chloride) current that modulates melanosomal pH for optimal tyrosinase activity required for melanogenesis and the melanosome maturation. One of the components of the mammalian pigmentary system. May serve as a key control point at which ethnic skin color variation is determined. Major determinant of brown and/or blue eye color (By similarity). Seems to regulate the post-translational processing of tyrosinase, which catalyzes the limiting reaction in melanin synthesis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005254 chloride channel activity", "go_cellular_component": "GO:0033162 melanosome membrane", "go_biological_process": "GO:0042438 melanin biosynthetic process;GO:0035752 lysosomal lumen pH elevation;GO:0030318 melanocyte differentiation;GO:0006583 melanin biosynthetic process from tyrosine", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8MIQ9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MJ30-1", "uniprot_id": [ { "id": "DHPR_PIG", "url": "https://www.uniprot.org/uniprot/Q8MJ30", "type": "external" } ], "mass": 25758.0, "length": 243, "protein_name": "Dihydropteridine reductase", "gene_name": "QDPR", "organism": "Pig", "refseq_name": "dihydropteridine reductase", "refseq_ac": [ { "id": "NP_999508", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999508", "type": "external" } ], "gene_names_uniprotkb": "QDPR; DHPR", "gene_names_refseq": "QDPR", "protein_names_uniprotkb": "Dihydropteridine reductase; 1.5.1.34; HDHPR; Quinoid dihydropteridine reductase", "protein_names_refseq": "HDHPR; dihydropteridine reductase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397619)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12464030", "class_list": "", "function": "Catalyzes the conversion of quinonoid dihydrobiopterin into tetrahydrobiopterin., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070402 NADPH binding;GO:0004155 6,7-dihydropteridine reductase activity;GO:0070404 NADH binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006559 L-phenylalanine catabolic process;GO:0006729 tetrahydrobiopterin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8MJ30-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MJ39-1", "uniprot_id": [ { "id": "MGP_PIG", "url": "https://www.uniprot.org/uniprot/Q8MJ39", "type": "external" } ], "mass": 12142.0, "length": 103, "protein_name": "Matrix Gla protein", "gene_name": "MGP", "organism": "Pig", "refseq_name": "matrix Gla protein precursor", "refseq_ac": [ { "id": "NP_999281", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999281", "type": "external" } ], "gene_names_uniprotkb": "MGP", "gene_names_refseq": "MGP; MPG", "protein_names_uniprotkb": "Matrix Gla protein; MGP", "protein_names_refseq": "matrix Gla protein precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397206)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "20362039;32543654", "class_list": "", "function": "Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation., [UniProtKB, UniProtKB, UniProtKB]; High DNA methylation resulting in the down regulation of matrix Gla protein is associated with osteochondrosis., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix", "go_biological_process": "GO:0030154 cell differentiation;GO:0001503 ossification;GO:0030500 regulation of bone mineralization;GO:0051216 cartilage development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8MJ39-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8MJ80-1", "uniprot_id": [ { "id": "HEPC_PIG", "url": "https://www.uniprot.org/uniprot/Q8MJ80", "type": "external" } ], "mass": 8771.0, "length": 82, "protein_name": "Hepcidin", "gene_name": "HAMP", "organism": "Pig", "refseq_name": "hepcidin precursor", "refseq_ac": [ { "id": "NP_999282", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999282", "type": "external" } ], "gene_names_uniprotkb": "HAMP", "gene_names_refseq": "HAMP", "protein_names_uniprotkb": "Hepcidin", "protein_names_refseq": "antimicrobial peptide hepcidin; hepcidin precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397207)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "16051358;25774043;26323096", "class_list": "", "function": "Data suugest that hepcidin might had antiinflammatory function and is a candidate regulator of the cross-talk between iron regulation and inflammation., [RefSeq, PubMed]; Has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus and group b streptococcus bacteria. Active against the fungus C.albicans. No activity against P.aeruginosa., [UniProtKB, UniProtKB]; Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin/SLC40A1, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes., [UniProtKB, UniProtKB]; Report the full-length cDNA sequences of porcine hepcidin and liver-expressed antimicrobial peptide-2 (LEAP-2), [RefSeq, PubMed]; This study demonstrates that urine hepcidin-25 concentrations strongly correlate with hepatic hepcidin mRNA abundance, plasma hepcidin-25 levels, iron transferrin saturation and non-heme liver iron levels. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005179 hormone activity;GO:0141108 transporter regulator activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis;GO:0042742 defense response to bacterium;GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0010039 response to iron ion;GO:0034760 negative regulation of iron ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8MJ80-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8SPJ9-1", "uniprot_id": [ { "id": "CX7A1_PIG", "url": "https://www.uniprot.org/uniprot/Q8SPJ9", "type": "external" } ], "mass": 9014.0, "length": 80, "protein_name": "Cytochrome c oxidase subunit 7A1, mitochondrial", "gene_name": "COX7A1", "organism": "Pig", "refseq_name": "cytochrome c oxidase subunit 7A1, mitochondrial precursor", "refseq_ac": [ { "id": "NP_999576", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999576", "type": "external" } ], "gene_names_uniprotkb": "COX7A1", "gene_names_refseq": "COX7A1", "protein_names_uniprotkb": "Cytochrome c oxidase subunit 7A1, mitochondrial; Cytochrome c oxidase subunit VIIa-H; Cytochrome c oxidase subunit VIIa-heart", "protein_names_refseq": "cytochrome c oxidase polypeptide VIIa-muscle/heart; cytochrome c oxidase subunit 7A1, mitochondrial precursor; cytochrome c oxidase subunit 7A1, mitochondrial; cytochrome c oxidase subunit VIIa-H; cytochrome c oxidase subunit VIIa-heart", "tax_id": 9823, "disease": "", "pathway": " (ssc:399685); (R-SSC-5628897); (R-SSC-611105); (R-SSC-9707564); (R-SSC-9864848)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "11856879", "class_list": "", "function": "Component of the mitochondrial respiratory complex IV (CIV, also named cytochrome c oxidase complex), the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation (By similarity). The CIV complex is the component of the respiratory chain that catalyzes the reduction of oxygen to water (By similarity). Acts as an assembly factor that specifically drives the homodimerization of CIV complexes, mediating the formation of mitochondrial respiratory supercomplexes (respirasomes) containing two CIV: supercomplxes with two molecules of CIV show improved activity (By similarity). Despite being highly expressed in brown adipose tissue, not required for thermogenesis (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0016491 oxidoreductase activity;GO:0004129 cytochrome-c oxidase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0031966 mitochondrial membrane;GO:0045277 respiratory chain complex IV;GO:0098803 respiratory chain complex", "go_biological_process": "GO:0006123 mitochondrial electron transport, cytochrome c to oxygen;GO:0006119 oxidative phosphorylation;GO:0097250 mitochondrial respirasome assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8SPJ9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8SPK0-1", "uniprot_id": [ { "id": "CP4AP_PIG", "url": "https://www.uniprot.org/uniprot/Q8SPK0", "type": "external" } ], "mass": 57324.0, "length": 504, "protein_name": "Cytochrome P450 4A25", "gene_name": "CYP4A25", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CYP4A25", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytochrome P450 4A25; 1.14.14.80; CYPIVA25; Fatty acid omega-hydroxylase; Long-chain fatty acid omega-monooxygenase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "11931657", "class_list": "", "function": "Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate and palmitate. Has no activity toward taurochenodeoxycholic acid., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0102033 long-chain fatty acid omega-hydroxylase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8SPK0-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8SQ26-1", "uniprot_id": [ { "id": "CRYL1_PIG", "url": "https://www.uniprot.org/uniprot/Q8SQ26", "type": "external" } ], "mass": 35128.0, "length": 322, "protein_name": "Lambda-crystallin homolog", "gene_name": "CRYL1", "organism": "Pig", "refseq_name": "lambda-crystallin homolog", "refseq_ac": [ { "id": "NP_999046", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999046", "type": "external" } ], "gene_names_uniprotkb": "CRYL1; CRY", "gene_names_refseq": "CRYL1; CRY; GulDH", "protein_names_uniprotkb": "Lambda-crystallin homolog; 1.1.1.45; Gul3DH; L-gulonate 3-dehydrogenase", "protein_names_refseq": "L-gulonate 3-dehydrogenase; gul3DH; lambda-crystallin homolog", "tax_id": 9823, "disease": "", "pathway": " (ssc:396914)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12527201", "class_list": "", "function": "Catalyzes the conversion of L-gulonate to 3-dehydro-L-gulonate (By similarity). It also exhibits low dehydrogenase activity toward L-3-hydroxybutyrate (HBA) and L-threonate (By similarity). Utilizes NAD as the sole cosubstrate and shows no activity with NADP (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0050104 L-gulonate 3-dehydrogenase activity;GO:0070403 NAD+ binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006631 fatty acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8SQ26-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8WMR7-1", "uniprot_id": [ { "id": "BEST1_PIG", "url": "https://www.uniprot.org/uniprot/Q8WMR7", "type": "external" } ], "mass": 66643.0, "length": 581, "protein_name": "Bestrophin-1", "gene_name": "BEST1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "BEST1; VMD2", "gene_names_refseq": "", "protein_names_uniprotkb": "Bestrophin-1; Vitelliform macular dystrophy protein 2 homolog", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "12058047", "class_list": "", "function": "Ligand-gated anion channel that allows the movement of anions across cell membranes when activated by calcium (Ca2+). Allows the movement of chloride and hydrogencarbonate. Found in a partially open conformation leading to significantly smaller chloride movement (By similarity). Upon F2R/PAR-1 activation, the sequestered calcium is released into the cytosol of astrocytes, leading to the (Ca2+)-dependent release of L-glutamate into the synaptic cleft that targets the neuronal postsynaptic GRIN2A/NMDAR receptor resulting in the synaptic plasticity regulation. Upon activation of the norepinephrine-alpha-1 adrenergic receptor signaling pathway, transports as well D-serine than L-glutamate in a (Ca2+)-dependent manner, leading to activation of adjacent NMDAR receptors and therefore regulates the heterosynaptic long-term depression and metaplasticity during initial memory acquisition. Releases the 4-aminobutanoate neurotransmitter in a (Ca2+)-dependent manner, and participates in its tonic release from cerebellar glial cells (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "I3LNI9", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0005229 intracellularly calcium-gated chloride channel activity;GO:0005254 chloride channel activity;GO:0022834 ligand-gated channel activity;GO:0160133 bicarbonate channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0034707 chloride channel complex;GO:0098793 presynapse;GO:0098857 membrane microdomain", "go_biological_process": "GO:0051259 protein complex oligomerization;GO:0048167 regulation of synaptic plasticity;GO:1902476 chloride transmembrane transport;GO:0014047 glutamate secretion;GO:0061534 gamma-aminobutyric acid secretion, neurotransmission", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8WMR7-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q8WNE9-1", "uniprot_id": [ { "id": "BAALC_PIG", "url": "https://www.uniprot.org/uniprot/Q8WNE9", "type": "external" } ], "mass": 15401.0, "length": 145, "protein_name": "Brain and acute leukemia cytoplasmic protein", "gene_name": "BAALC", "organism": "Pig", "refseq_name": "brain and acute leukemia cytoplasmic protein", "refseq_ac": [ { "id": "NP_001123441", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001123441", "type": "external" } ], "gene_names_uniprotkb": "BAALC", "gene_names_refseq": "BAALC", "protein_names_uniprotkb": "Brain and acute leukemia cytoplasmic protein", "protein_names_refseq": "BAALC, MAP3K1 and KLF4 binding; brain and acute leukemia cytoplasmic protein; brain and acute leukemia, cytoplasmic", "tax_id": 9823, "disease": "", "pathway": " (ssc:100170128)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "11707601", "class_list": "", "function": "May play a synaptic role at the postsynaptic lipid rafts possibly through interaction with CAMK2A., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8WNE8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0014069 postsynaptic density;GO:0045121 membrane raft;GO:0043005 neuron projection", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8WNE9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95245-1", "uniprot_id": [ { "id": "CY561_PIG", "url": "https://www.uniprot.org/uniprot/Q95245", "type": "external" } ], "mass": 27556.0, "length": 252, "protein_name": "Transmembrane ascorbate-dependent reductase CYB561", "gene_name": "CYB561", "organism": "Pig", "refseq_name": "transmembrane ascorbate-dependent reductase CYB561", "refseq_ac": [ { "id": "NP_001090991", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001090991", "type": "external" } ], "gene_names_uniprotkb": "CYB561", "gene_names_refseq": "CYB561", "protein_names_uniprotkb": "Transmembrane ascorbate-dependent reductase CYB561; 7.2.1.-; Cytochrome b-561; Cytochrome b561", "protein_names_refseq": "cytochrome b-561; transmembrane ascorbate-dependent reductase CYB561", "tax_id": 9823, "disease": "", "pathway": " (ssc:100048996)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "9602148", "class_list": "", "function": "Transmembrane reductase that uses ascorbate as an electron donor in the cytoplasm and transfers electrons across membranes to reduce monodehydro-L-ascorbate radical in the lumen of secretory vesicles. It is therefore involved the regeneration and homeostasis within secretory vesicles of ascorbate which in turn provides reducing equivalents needed to support the activity of intravesicular enzymes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0016491 oxidoreductase activity;GO:0140575 transmembrane monodehydroascorbate reductase activity", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0042584 chromaffin granule membrane", "go_biological_process": "GO:0140576 ascorbate homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q95245-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95253-1", "uniprot_id": [ { "id": "IL15_PIG", "url": "https://www.uniprot.org/uniprot/Q95253", "type": "external" } ], "mass": 18437.0, "length": 162, "protein_name": "Interleukin-15", "gene_name": "IL15", "organism": "Pig", "refseq_name": "interleukin-15 precursor", "refseq_ac": [ { "id": "NP_999555", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999555", "type": "external" } ], "gene_names_uniprotkb": "IL15", "gene_names_refseq": "IL-15; IL15", "protein_names_uniprotkb": "Interleukin-15; IL-15", "protein_names_refseq": "interleukin-15 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397683)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14656772;15155279;22573868;25098601;29168191;9305780", "class_list": "", "function": "Cytokine that plays a major role in the development of inflammatory and protective immune responses to microbial invaders and parasites by modulating immune cells of both the innate and adaptive immune systems. Stimulates the proliferation of natural killer cells, T-cells and B-cells and promotes the secretion of several cytokines. In monocytes, induces the production of IL8 and monocyte chemotactic protein 1/CCL2, two chemokines that attract neutrophils and monocytes respectively to sites of infection. Unlike most cytokines, which are secreted in soluble form, IL15 is expressed in association with its high affinity IL15RA on the surface of IL15-producing cells and delivers signals to target cells that express IL2RB and IL2RG receptor subunits. Binding to its receptor triggers the phosphorylation of JAK1 and JAK3 and the recruitment and subsequent phosphorylation of signal transducer and activator of transcription-3/STAT3 and STAT5 (By similarity). In mast cells, induces the rapid tyrosine phosphorylation of STAT6 and thereby controls mast cell survival and release of cytokines such as IL4 (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; IFN-gamma targets the adipocyte to induce IL-15 expression, thus indicating a possible role for the adipocyte in the regulation of T-cell function and muscle metabolism during the innate immune response, [RefSeq, PubMed]; Myokine IL-15 regulates the crosstalk of co-cultured porcine skeletal muscle satellite cells and preadipocytes., [RefSeq, PubMed]; Results demonstrate that porcine reproductive and respiratory syndrome virus (PRRSV)infection could induce IL-15 production in macrophages/dendritic cells; data further show that upregulation of IL-15 by PRRSV requires PKC and NF-kappaB pathways, [RefSeq, PubMed]; Study identified two completely linked SNPs in the porcine IL15 promoter region that could alter IL15 transcription activity. As interleukin-15 can inhibit porcine adipocyte differentiation, these promoter mutations could affect intramuscular fat deposition by producing differential levels of muscle-derived interleukin-15., [RefSeq, PubMed]; When induced by IFN-gamma or other inflammatory mediators, IL-15 may be a significant homeorhetic factor that mobilizes and directs energy away from the adipocyte to other cells during the acute phase of the inflammatory response., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q195F8", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0005126 cytokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006955 immune response;GO:0001819 positive regulation of cytokine production;GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation;GO:0050766 positive regulation of phagocytosis;GO:0042102 positive regulation of T cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q95253-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95276-1", "uniprot_id": [ { "id": "RL5_PIG", "url": "https://www.uniprot.org/uniprot/Q95276", "type": "external" } ], "mass": 14670.0, "length": 125, "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "RPL5", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "RPL5", "gene_names_refseq": "", "protein_names_uniprotkb": "Large ribosomal subunit protein uL18; 60S ribosomal protein L5", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. As part of the 5S RNP/5S ribonucleoprotein particle it is an essential component of the LSU, required for its formation and the maturation of rRNAs. It also couples ribosome biogenesis to p53/TP53 activation. As part of the 5S RNP it accumulates in the nucleoplasm and inhibits MDM2, when ribosome biogenesis is perturbed, mediating the stabilization and the activation of TP53., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008097 5S rRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q95276-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95283-1", "uniprot_id": [ { "id": "COX41_PIG", "url": "https://www.uniprot.org/uniprot/Q95283", "type": "external" } ], "mass": 11048.0, "length": 97, "protein_name": "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial", "gene_name": "COX4I1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "COX4I1; COX4", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; COX IV-1; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045277 respiratory chain complex IV", "go_biological_process": "GO:0006123 mitochondrial electron transport, cytochrome c to oxygen", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q95283-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95307-1", "uniprot_id": [ { "id": "RL13A_PIG", "url": "https://www.uniprot.org/uniprot/Q95307", "type": "external" } ], "mass": 15674.0, "length": 137, "protein_name": "Large ribosomal subunit protein uL13", "gene_name": "RPL13A", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "RPL13A", "gene_names_refseq": "", "protein_names_uniprotkb": "Large ribosomal subunit protein uL13; 60S ribosomal protein L13a", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P79320", "ec_number_list": [], "go_molecular_function": "GO:0003729 mRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005840 ribosome;GO:0097452 GAIT complex;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0017148 negative regulation of translation;GO:1901194 negative regulation of formation of translation preinitiation complex", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q95307-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95312-1", "uniprot_id": [ { "id": "ATPD_PIG", "url": "https://www.uniprot.org/uniprot/Q95312", "type": "external" } ], "mass": 8302.0, "length": 80, "protein_name": "ATP synthase F(1) complex subunit delta, mitochondrial", "gene_name": "ATP5F1D", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ATP5F1D; ATP5D", "gene_names_refseq": "", "protein_names_uniprotkb": "ATP synthase F(1) complex subunit delta, mitochondrial; ATP synthase F1 subunit delta; F-ATPase delta subunit", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Subunit delta, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). With the central stalk subunit gamma, is essential for the biogenesis of F(1) catalytic part of the ATP synthase complex namely in the formation of F1 assembly intermediate (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005198 structural molecule activity;GO:0046933 proton-transporting ATP synthase activity, rotational mechanism", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly;GO:0009060 aerobic respiration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q95312-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95J46-1", "uniprot_id": [ { "id": "UTS2_PIG", "url": "https://www.uniprot.org/uniprot/Q95J46", "type": "external" } ], "mass": 13580.0, "length": 121, "protein_name": "Urotensin-2", "gene_name": "UTS2", "organism": "Pig", "refseq_name": "urotensin-2 precursor", "refseq_ac": [ { "id": "NP_999308", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999308", "type": "external" } ], "gene_names_uniprotkb": "UTS2", "gene_names_refseq": "UTS2", "protein_names_uniprotkb": "Urotensin-2; U-II; UII; Urotensin II", "protein_names_refseq": "U-II; UII; urotensin II; urotensin-2 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397268)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "10548501", "class_list": "", "function": "Highly potent vasoconstrictor., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95K72", "ec_number_list": [], "go_molecular_function": "GO:0005179 hormone activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0008217 regulation of blood pressure;GO:0097746 blood vessel diameter maintenance", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q95J46-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95JA5-1", "uniprot_id": [ { "id": "GATA6_PIG", "url": "https://www.uniprot.org/uniprot/Q95JA5", "type": "external" } ], "mass": 45410.0, "length": 451, "protein_name": "Transcription factor GATA-6", "gene_name": "GATA6", "organism": "Pig", "refseq_name": "transcription factor GATA-6", "refseq_ac": [ { "id": "NP_999493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999493", "type": "external" } ], "gene_names_uniprotkb": "GATA6", "gene_names_refseq": "GATA-6; GATA6", "protein_names_uniprotkb": "Transcription factor GATA-6; GATA-binding factor 6", "protein_names_refseq": "GATA-binding factor 6; transcription factor GATA-6", "tax_id": 9823, "disease": "", "pathway": " (ssc:397600)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "18653717;20739664", "class_list": "", "function": "Investigation of genes regulated by GATA6, GATA4, and both in combination: studies in granulosa cells primed for luteinization, [RefSeq, PubMed]; The altered ratio of GATA4 to GATA6 after ovulation may allow GATA6 to enhance STAR mRNA accumulation., [RefSeq, PubMed]; Transcriptional activator that regulates SEMA3C and PLXNA2. May regulate genes that protect epithelial cells from bacterial infection. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007507 heart development;GO:0030855 epithelial cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q95JA5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95L04-1", "uniprot_id": [ { "id": "UPK2_PIG", "url": "https://www.uniprot.org/uniprot/Q95L04", "type": "external" } ], "mass": 19318.0, "length": 184, "protein_name": "Uroplakin-2", "gene_name": "UPK2", "organism": "Pig", "refseq_name": "uroplakin-2 precursor", "refseq_ac": [ { "id": "NP_999177", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999177", "type": "external" } ], "gene_names_uniprotkb": "UPK2", "gene_names_refseq": "UP2; UPII; UPK2", "protein_names_uniprotkb": "Uroplakin-2; UP2; UPII; Uroplakin II", "protein_names_refseq": "Uroplakin-2; uroplakin II; uroplakin-2 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397075)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12054551;16619260;21658368", "class_list": "", "function": "All the major trans-regulatory elements required for bladder- and urethra-specific transcription are located in the 8.8 kb promoter upstream region, [RefSeq, PubMed]; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in regulating the assembly of the AUM (By similarity)., [UniProtKB]; HNF4 positively regulates pUPII gene promoter activity., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q7M2K0;Q9TUP8", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0016324 apical plasma membrane", "go_biological_process": "GO:0030855 epithelial cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q95L04-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95LB4-1", "uniprot_id": [ { "id": "FATE1_PIG", "url": "https://www.uniprot.org/uniprot/Q95LB4", "type": "external" } ], "mass": 19065.0, "length": 171, "protein_name": "Fetal and adult testis-expressed transcript protein homolog", "gene_name": "FATE1", "organism": "Pig", "refseq_name": "fetal and adult testis-expressed transcript protein homolog", "refseq_ac": [ { "id": "NP_998962", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998962", "type": "external" } ], "gene_names_uniprotkb": "FATE1; FATE", "gene_names_refseq": "FATE1; FATE", "protein_names_uniprotkb": "Fetal and adult testis-expressed transcript protein homolog", "protein_names_refseq": "fetal and adult testis expressed transcript; fetal and adult testis-expressed transcript protein homolog", "tax_id": 9823, "disease": "", "pathway": " (ssc:396705)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "11694338", "class_list": "", "function": "Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site", "go_biological_process": "GO:0051562 negative regulation of mitochondrial calcium ion concentration;GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q95LB4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95N02-1", "uniprot_id": [ { "id": "CLTR1_PIG", "url": "https://www.uniprot.org/uniprot/Q95N02", "type": "external" } ], "mass": 38989.0, "length": 340, "protein_name": "Cysteinyl leukotriene receptor 1", "gene_name": "CYSLTR1", "organism": "Pig", "refseq_name": "cysteinyl leukotriene receptor 1", "refseq_ac": [ { "id": "NP_999294", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999294", "type": "external" } ], "gene_names_uniprotkb": "CYSLTR1; CYSLT1", "gene_names_refseq": "CYCLT1; CYSLTR1", "protein_names_uniprotkb": "Cysteinyl leukotriene receptor 1; CysLTR1", "protein_names_refseq": "CysLT1 receptor; cysteinyl leukotriene receptor 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397242)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Receptor for cysteinyl leukotrienes mediating constriction of the microvascular smooth muscle during an inflammatory response. This response is mediated via a G protein that activates a phosphatidylinositol-calcium second messenger system (By similarity)., [UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004974 leukotriene receptor activity;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q95N02-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q95N03-1", "uniprot_id": [ { "id": "CLTR2_PIG", "url": "https://www.uniprot.org/uniprot/Q95N03", "type": "external" } ], "mass": 39411.0, "length": 345, "protein_name": "Cysteinyl leukotriene receptor 2", "gene_name": "CYSLTR2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CYSLTR2; CYSLT2", "gene_names_refseq": "", "protein_names_uniprotkb": "Cysteinyl leukotriene receptor 2; CysLTR2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Receptor for cysteinyl leukotrienes. The response is mediated via a G protein that activates a phosphatidylinositol-calcium second messenger system (By similarity)., [UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0001631 cysteinyl leukotriene receptor activity;GO:0004966 galanin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007218 neuropeptide signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q95N03-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9BDP6-1", "uniprot_id": [ { "id": "PTTG1_PIG", "url": "https://www.uniprot.org/uniprot/Q9BDP6", "type": "external" } ], "mass": 13564.0, "length": 121, "protein_name": "Securin", "gene_name": "PTTG1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PTTG1; PTTG", "gene_names_refseq": "", "protein_names_uniprotkb": "Securin; Pituitary tumor-transforming gene 1 protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESPL1. Its function is however not limited to a blocking activity, since it is required to activate ESPL1. Negatively regulates the transcriptional activity and related apoptosis activity of p53/TP53. The negative regulation of p53/TP53 may explain the strong transforming capability of the protein when it is overexpressed. May also play a role in DNA repair via its interaction with Ku, possibly by connecting DNA damage-response pathways with sister chromatid separation (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017124 SH3 domain binding;GO:0004869 cysteine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0045143 homologous chromosome segregation;GO:0006281 DNA repair;GO:0051301 cell division;GO:0051276 chromosome organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9BDP6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9BDP9-1", "uniprot_id": [ { "id": "CART_PIG", "url": "https://www.uniprot.org/uniprot/Q9BDP9", "type": "external" } ], "mass": 7451.0, "length": 66, "protein_name": "Cocaine- and amphetamine-regulated transcript protein", "gene_name": "CARTPT", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CARTPT; CART", "gene_names_refseq": "", "protein_names_uniprotkb": "Cocaine- and amphetamine-regulated transcript protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Satiety factor closely associated with the actions of leptin and neuropeptide y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005184 neuropeptide hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0045202 synapse", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007218 neuropeptide signaling pathway;GO:0043410 positive regulation of MAPK cascade;GO:0045777 positive regulation of blood pressure;GO:0007268 chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9BDP9-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9BDY7-1", "uniprot_id": [ { "id": "ANGP2_PIG", "url": "https://www.uniprot.org/uniprot/Q9BDY7", "type": "external" } ], "mass": 56911.0, "length": 496, "protein_name": "Angiopoietin-2", "gene_name": "ANGPT2", "organism": "Pig", "refseq_name": "angiopoietin-2 precursor", "refseq_ac": [ { "id": "NP_998973", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998973", "type": "external" } ], "gene_names_uniprotkb": "ANGPT2", "gene_names_refseq": "ANG2; ANGPT2", "protein_names_uniprotkb": "Angiopoietin-2; ANG-2", "protein_names_refseq": "ANG-2; angiopoietin-2 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:396730)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11230987;20598355;20713984;29885854", "class_list": "", "function": "ANGPT2 remained upregulated during maturation of glomeruli, which may be explained by the continuous growth of the glomeruli, as observed by stereological examination., [RefSeq, PubMed]; Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling (By similarity). Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1 (By similarity). In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression (By similarity). In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal (By similarity). Involved in the regulation of lymphangiogenesis (By similarity)., [UniProtKB, UniProtKB]; Expression of angiopoietin 2 in the porcine metanephric kidney was observed in the podocytes of early developing glomeruli, but not in the cells near the glomerular hilus, [RefSeq, PubMed]; The presence of angiopoietins in the trophoblast suggests a specific role for these pro-angiogenic factors in the tissue formation at the maternal-fetal interface., [RefSeq, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0030971 receptor tyrosine kinase binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0001525 angiogenesis;GO:0030154 cell differentiation;GO:0007596 blood coagulation;GO:0048014 Tie signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9BDY7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9BDY8-1", "uniprot_id": [ { "id": "ANGP1_PIG", "url": "https://www.uniprot.org/uniprot/Q9BDY8", "type": "external" } ], "mass": 57413.0, "length": 498, "protein_name": "Angiopoietin-1", "gene_name": "ANGPT1", "organism": "Pig", "refseq_name": "angiopoietin-1 precursor", "refseq_ac": [ { "id": "NP_999124", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999124", "type": "external" } ], "gene_names_uniprotkb": "ANGPT1", "gene_names_refseq": "AGPT; ANGPT1", "protein_names_uniprotkb": "Angiopoietin-1; ANG-1", "protein_names_refseq": "ANG-1; angiopoietin-1 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397009)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11230987;16000309;17496211;20598355;20713984;29885854", "class_list": "", "function": "Angiopoietin 1 was predominantly present in the maturing glomeruli., [RefSeq, PubMed]; Attenuates H2O2-induced stress-activated protein kinase (SEK)1/JNK phosphorylation through the PI 3-kinase/Akt pathway and inhibits the apoptosis of vascular endothelial cells induced by oxidative stress., [RefSeq, PubMed]; Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development (By similarity)., [UniProtKB]; Estrogen-dependent control of Ang-1 expression plays an important role in stabilizing meningeal microvessel and maintaining healthy microvascular networks., [RefSeq, PubMed]; The expression of ANGPT1 has already been studied during metanephric glomerulogenesis, but it remains to be elucidated during the development of the embryonic mesonephros., [RefSeq, PubMed]; The presence of angiopoietins in the trophoblast suggests a specific role for these pro-angiogenic factors in the tissue formation at the maternal-fetal interface., [RefSeq, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030971 receptor tyrosine kinase binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0001525 angiogenesis;GO:0030154 cell differentiation;GO:0043066 negative regulation of apoptotic process;GO:0007596 blood coagulation;GO:0048014 Tie signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9BDY8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9GK37-1", "uniprot_id": [ { "id": "CBG_PIG", "url": "https://www.uniprot.org/uniprot/Q9GK37", "type": "external" } ], "mass": 45189.0, "length": 406, "protein_name": "Corticosteroid-binding globulin", "gene_name": "Serpina6", "organism": "Pig", "refseq_name": "corticosteroid-binding globulin precursor", "refseq_ac": [ { "id": "NP_998977", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998977", "type": "external" } ], "gene_names_uniprotkb": "Serpina6; Cbg", "gene_names_refseq": "CBG; SERPINA6", "protein_names_uniprotkb": "Corticosteroid-binding globulin; CBG; Serpin A6; Transcortin", "protein_names_refseq": "corticosteroid-binding globulin precursor; corticosteroid-binding globulin; serpin A6; transcortin", "tax_id": 9823, "disease": "", "pathway": " (ssc:396736)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15087473;17613944;21054451;25754835", "class_list": "", "function": "Cbg gene is a key regulator of cortisol levels and obesity susceptibility., [RefSeq, PubMed]; Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species., [UniProtKB, PubMed]; Negative relationship exists between plasma cortisol and CBG under conditions of acute stress., [RefSeq, PubMed]; Non-synonymous polymorphisms of SERPINA6, particularly SNPs c.919G>A and c.44G>T/c.622C>T, are associated with cortisol level, HPA axis activity, and carcass and meat quality traits, [RefSeq, PubMed]; The putative causal amino acid substitution p.Gly307Arg (SNP c.919G>A) associated with meat quality (drip loss) was only detected in European domestic pig breeds, suggesting a very recent mutation that appeared after domestication in Europe., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity;GO:0005496 steroid binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9GK37-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9GKE2-1", "uniprot_id": [ { "id": "CXL16_PIG", "url": "https://www.uniprot.org/uniprot/Q9GKE2", "type": "external" } ], "mass": 27570.0, "length": 250, "protein_name": "C-X-C motif chemokine 16", "gene_name": "CXCL16", "organism": "Pig", "refseq_name": "C-X-C motif chemokine 16 precursor", "refseq_ac": [ { "id": "NP_998976", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998976", "type": "external" } ], "gene_names_uniprotkb": "CXCL16", "gene_names_refseq": "CXCL16; SR-PSOX", "protein_names_uniprotkb": "C-X-C motif chemokine 16; Transmembrane chemokine CXCL16", "protein_names_refseq": "C-X-C motif chemokine 16 precursor; C-X-C motif chemokine 16; Transmembrane chemokine CXCL16; scavenger receptor for phosphatidylserine and oxidized low density lipoprotein", "tax_id": 9823, "disease": "", "pathway": " (ssc:396735); (R-SSC-380108); (R-SSC-418594)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "11060282", "class_list": "", "function": "Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. Also acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005044 scavenger receptor activity;GO:0005041 low-density lipoprotein particle receptor activity;GO:0008009 chemokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane", "go_biological_process": "GO:0030307 positive regulation of cell growth;GO:0030335 positive regulation of cell migration;GO:0034612 response to tumor necrosis factor;GO:0006898 receptor-mediated endocytosis;GO:0010818 T cell chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9GKE2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9GKQ6-1", "uniprot_id": [ { "id": "PGS1_PIG", "url": "https://www.uniprot.org/uniprot/Q9GKQ6", "type": "external" } ], "mass": 30457.0, "length": 272, "protein_name": "Biglycan", "gene_name": "BGN", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "BGN", "gene_names_refseq": "", "protein_names_uniprotkb": "Biglycan; Bone/cartilage proteoglycan I; PG-S1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in collagen fiber assembly., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q9TTB5", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9GKQ6-1", "record_type": "protein", "filter_code": "0000000.0000000.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9GKX6-1", "uniprot_id": [ { "id": "GALM_PIG", "url": "https://www.uniprot.org/uniprot/Q9GKX6", "type": "external" } ], "mass": 37816.0, "length": 342, "protein_name": "Galactose mutarotase", "gene_name": "GALM", "organism": "Pig", "refseq_name": "galactose mutarotase", "refseq_ac": [ { "id": "NP_999571", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999571", "type": "external" } ], "gene_names_uniprotkb": "GALM", "gene_names_refseq": "GALM; MUT", "protein_names_uniprotkb": "Galactose mutarotase; 5.1.3.3; Aldose 1-epimerase", "protein_names_refseq": "aldose 1-epimerase; galactose mutarotase", "tax_id": 9823, "disease": "", "pathway": " (ssc:399536); (R-SSC-70370)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism. Beta-D-galactose is metabolized in the liver into glucose 1-phosphate, the primary metabolic fuel, by the action of four enzymes that constitute the Leloir pathway: GALM, GALK1 (galactokinase), GALT (galactose-1-phosphate uridylyltransferase) and GALE (UDP-galactose-4'-epimerase). Involved in the maintenance of the equilibrium between the beta- and alpha-anomers of galactose, therefore ensuring a sufficient supply of the alpha-anomer for GALK1. Also active on D-glucose although shows a preference for galactose over glucose., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030246 carbohydrate binding;GO:0004034 aldose 1-epimerase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006006 glucose metabolic process;GO:0033499 galactose catabolic process via UDP-galactose, Leloir pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9GKX6-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9GL01-1", "uniprot_id": [ { "id": "RPN2_PIG", "url": "https://www.uniprot.org/uniprot/Q9GL01", "type": "external" } ], "mass": 69274.0, "length": 629, "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "gene_name": "RPN2", "organism": "Pig", "refseq_name": "dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 precursor", "refseq_ac": [ { "id": "NP_999106", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999106", "type": "external" } ], "gene_names_uniprotkb": "RPN2", "gene_names_refseq": "RPN-II; RPN2", "protein_names_uniprotkb": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit; RPN-II; Ribophorin II; Ribophorin-2", "protein_names_refseq": "dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 precursor; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; ribophorin-2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100154432)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11443278;40973947", "class_list": "", "function": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0008250 oligosaccharyltransferase complex", "go_biological_process": "GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9GL01-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0100000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9GL50-1", "uniprot_id": [ { "id": "STEA1_PIG", "url": "https://www.uniprot.org/uniprot/Q9GL50", "type": "external" } ], "mass": 39918.0, "length": 338, "protein_name": "STEAP1 protein", "gene_name": "STEAP1", "organism": "Pig", "refseq_name": "STEAP1 protein", "refseq_ac": [ { "id": "NP_999470", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999470", "type": "external" } ], "gene_names_uniprotkb": "STEAP1; STEAP", "gene_names_refseq": "STEAP1; STEAP", "protein_names_uniprotkb": "STEAP1 protein; Six transmembrane endothelial antigen of PAEC; Six-transmembrane epithelial antigen of prostate 1", "protein_names_refseq": "STEAP1 protein; metalloreductase STEAP1; six transmembrane endothelial antigen of PAEC; six-transmembrane epithelial antigen of prostate 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397573)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Does not function as a metalloreductase due to the absence of binding sites for the electron-donating substrate NADPH., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0010008 endosome membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9GL50-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9GLL9-1", "uniprot_id": [ { "id": "PROP1_PIG", "url": "https://www.uniprot.org/uniprot/Q9GLL9", "type": "external" } ], "mass": 25214.0, "length": 226, "protein_name": "Homeobox protein prophet of Pit-1", "gene_name": "PROP1", "organism": "Pig", "refseq_name": "homeobox protein prophet of Pit-1", "refseq_ac": [ { "id": "NP_001001263", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001263", "type": "external" } ], "gene_names_uniprotkb": "PROP1", "gene_names_refseq": "PROP-1; PROP1", "protein_names_uniprotkb": "Homeobox protein prophet of Pit-1; PROP-1; Pituitary-specific homeodomain factor", "protein_names_refseq": "homeobox protein prophet of Pit-1; pituitary-specific homeodomain factor; prophet of Pit1, paired-like homeodomain transcription factor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397280)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11064154;15474519;16394624;19524124;19879326", "class_list": "", "function": "Data suggest that formation of a heterodimer between HESX1 and PROP1 allows HESX1 to become active, and that PROP1 then replaces HESX1 to advance to the middle stage of pituitary development., [RefSeq, PubMed]; Dimeric binding of PROP1 is able to recognize diverse palindromic TAAT sequences separated by 3 nucleotides and to exhibit its transcriptional activity., [RefSeq, PubMed]; Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes., [UniProtKB]; Prop-1 might be involved in development of gonadotropes and hormone production, [RefSeq, PubMed]; Prop-1 participates in the regulation of FSHbeta gene, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A2IBI2;Q5TLE9", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0021983 pituitary gland development", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9GLL9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9GLX8-1", "uniprot_id": [ { "id": "BKRB2_PIG", "url": "https://www.uniprot.org/uniprot/Q9GLX8", "type": "external" } ], "mass": 41781.0, "length": 367, "protein_name": "B2 bradykinin receptor", "gene_name": "BDKRB2", "organism": "Pig", "refseq_name": "B2 bradykinin receptor", "refseq_ac": [ { "id": "NP_999311", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999311", "type": "external" } ], "gene_names_uniprotkb": "BDKRB2", "gene_names_refseq": "B2R; BDKRB2", "protein_names_uniprotkb": "B2 bradykinin receptor; B2R; BK-2 receptor", "protein_names_refseq": "B2 bradykinin receptor; BK-2 receptor; bradykinin type 2 receptor", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "11673263;24833299;25078038", "class_list": "", "function": "A persistent B2R-beta2AR heterodimer was confirmed in bradykinin-stimulated and non-stimulated left ventricular myocardium. BK transactivation of beta2AR enhanced beta2AR-mediated release of tPA., [RefSeq, PubMed]; Bradykinin induces NO and PGF2alpha production via B2 receptor activation from cultured porcine basilar arterial endothelial cells, [RefSeq, PubMed]; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004947 bradykinin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0042311 vasodilation;GO:0042310 vasoconstriction;GO:0014832 urinary bladder smooth muscle contraction;GO:1900073 regulation of neuromuscular synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9GLX8-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000010001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9MYM5-1", "uniprot_id": [ { "id": "IL5_PIG", "url": "https://www.uniprot.org/uniprot/Q9MYM5", "type": "external" } ], "mass": 15191.0, "length": 134, "protein_name": "Interleukin-5", "gene_name": "IL5", "organism": "Pig", "refseq_name": "interleukin-5 precursor", "refseq_ac": [ { "id": "NP_999370", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999370", "type": "external" } ], "gene_names_uniprotkb": "IL5", "gene_names_refseq": "IL-5; IL5", "protein_names_uniprotkb": "Interleukin-5; Eosinophil differentiation factor; IL-5; T-cell replacing factor; TRF", "protein_names_refseq": "T-cell replacing factor; TRF; eosinophil differentiation factor; interleukin-5 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397409); (R-SSC-512988); (R-SSC-5673001); (R-SSC-912526)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "10663563", "class_list": "", "function": "Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Also acts on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation (By similarity). Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0008083 growth factor activity;GO:0005137 interleukin-5 receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0038043 interleukin-5-mediated signaling pathway;GO:0006955 immune response;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT;GO:0071803 positive regulation of podosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9MYM5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9MZ01-1", "uniprot_id": [ { "id": "MCHR1_PIG", "url": "https://www.uniprot.org/uniprot/Q9MZ01", "type": "external" } ], "mass": 39021.0, "length": 353, "protein_name": "Melanin-concentrating hormone receptor 1", "gene_name": "MCHR1", "organism": "Pig", "refseq_name": "melanin-concentrating hormone receptor 1", "refseq_ac": [ { "id": "NP_001008684", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008684", "type": "external" } ], "gene_names_uniprotkb": "MCHR1; GPR24", "gene_names_refseq": "GPR24; MCH-R1; MCHR1", "protein_names_uniprotkb": "Melanin-concentrating hormone receptor 1; G protein-coupled receptor 24; MCH receptor 1; MCH-1R; MCH-R1; MCH1R; MCHR-1; MCHR", "protein_names_refseq": "G-protein coupled receptor 24; MCH receptor 1; MCH-1R; MCH1R; MCHR-1; MCHR; melanin-concentrating hormone receptor 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397295)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "G protein-coupled receptor for melanin-concentrating hormone (MCH) that signals primarily through G(i/o) to inhibit adenylyl cyclase, and can additionally couple to G(q/11) to stimulate phospholipase C and mobilize intracellular calcium. Predominantly localized within the central nervous system where it regulates various physiological processes including feeding behavior, energy homeostasis, stress/anxiety-related behaviors and sleep., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "F1SRB6;Q5QPY1", "ec_number_list": [], "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0030273 melanin-concentrating hormone receptor activity", "go_cellular_component": "GO:0060170 ciliary membrane;GO:0097731 9+0 non-motile cilium", "go_biological_process": "GO:0007218 neuropeptide signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9MZ01-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9MZV8-1", "uniprot_id": [ { "id": "MC5R_PIG", "url": "https://www.uniprot.org/uniprot/Q9MZV8", "type": "external" } ], "mass": 32753.0, "length": 294, "protein_name": "Melanocortin receptor 5", "gene_name": "MC5R", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "MC5R", "gene_names_refseq": "", "protein_names_uniprotkb": "Melanocortin receptor 5; MC5-R", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "10895318", "class_list": "", "function": "G protein-coupled receptor for melanocyte-stimulating hormones (alpha- beta- and gamma-MSH) and corticotropin/ACTH, which are peptide products of the POMC precursor. Upon activation, couples to G(s) protein, stimulating adenylate cyclase and the cAMP-dependent signaling pathway. Also activates ERK1/2 via a PI3K-dependent signaling mechanism. Order of potency of natural melanocortins in receptor activation is alpha-MSH > ACTH > beta-MSH > gamma-MSH (By similarity). Plays a key role in immune response, and is essential for temperature regulation and exocrine gland function (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004977 melanocortin receptor activity;GO:0004978 corticotropin receptor activity;GO:0004980 melanocyte-stimulating hormone receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0001659 temperature homeostasis;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0050777 negative regulation of immune response;GO:0045921 positive regulation of exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9MZV8-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9TDR1-1", "uniprot_id": [ { "id": "NU5M_PIG", "url": "https://www.uniprot.org/uniprot/Q9TDR1", "type": "external" } ], "mass": 68650.0, "length": 606, "protein_name": "NADH-ubiquinone oxidoreductase chain 5", "gene_name": "MT-ND5", "organism": "Pig", "refseq_name": "NADH dehydrogenase subunit 5", "refseq_ac": [ { "id": "NP_008644", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_008644", "type": "external" } ], "gene_names_uniprotkb": "MT-ND5; MTND5; NADH5; ND5", "gene_names_refseq": "ND5", "protein_names_uniprotkb": "NADH-ubiquinone oxidoreductase chain 5; 7.1.1.2; NADH dehydrogenase subunit 5", "protein_names_refseq": "NADH dehydrogenase subunit 5", "tax_id": 9823, "disease": "", "pathway": " (ssc:808511); (R-SSC-5419276); (R-SSC-611105); (R-SSC-6799198)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "10433971;11428467", "class_list": "", "function": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9G7T6", "ec_number_list": [], "go_molecular_function": "GO:0008137 NADH dehydrogenase (ubiquinone) activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045271 respiratory chain complex I", "go_biological_process": "GO:0032981 mitochondrial respiratory chain complex I assembly;GO:0006120 mitochondrial electron transport, NADH to ubiquinone;GO:0015990 electron transport coupled proton transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9TDR1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9TSV7-1", "uniprot_id": [ { "id": "IKBL1_PIG", "url": "https://www.uniprot.org/uniprot/Q9TSV7", "type": "external" } ], "mass": 43031.0, "length": 380, "protein_name": "NF-kappa-B inhibitor-like protein 1", "gene_name": "NFKBIL1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "NFKBIL1; IKBL", "gene_names_refseq": "", "protein_names_uniprotkb": "NF-kappa-B inhibitor-like protein 1; I-kappa-B-like protein; IkappaBL; Inhibitor of kappa B-like protein; Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "11169259", "class_list": "", "function": "Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous pro-inflammatory stimuli (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A5D9N1", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0032720 negative regulation of tumor necrosis factor production;GO:0071222 cellular response to lipopolysaccharide;GO:0043124 negative regulation of canonical NF-kappaB signal transduction;GO:0034122 negative regulation of toll-like receptor signaling pathway;GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9TSV7-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9TSV8-1", "uniprot_id": [ { "id": "TNFC_PIG", "url": "https://www.uniprot.org/uniprot/Q9TSV8", "type": "external" } ], "mass": 16423.0, "length": 150, "protein_name": "Lymphotoxin-beta", "gene_name": "LTB", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LTB; TNFC; TNFSF3", "gene_names_refseq": "", "protein_names_uniprotkb": "Lymphotoxin-beta; LT-beta; TNF-C; Tumor necrosis factor C; Tumor necrosis factor ligand superfamily member 3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "11169259", "class_list": "", "function": "Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0005164 tumor necrosis factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0006955 immune response;GO:0007166 cell surface receptor signaling pathway;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:2001238 positive regulation of extrinsic apoptotic signaling pathway;GO:0032735 positive regulation of interleukin-12 production", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9TSV8-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9TSX5-1", "uniprot_id": [ { "id": "LDHC_PIG", "url": "https://www.uniprot.org/uniprot/Q9TSX5", "type": "external" } ], "mass": 36053.0, "length": 332, "protein_name": "L-lactate dehydrogenase C chain", "gene_name": "LDHC", "organism": "Pig", "refseq_name": "L-lactate dehydrogenase C chain", "refseq_ac": [ { "id": "NP_001182704", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182704", "type": "external" } ], "gene_names_uniprotkb": "LDHC", "gene_names_refseq": "LDH-C; LDH-X; LDHC", "protein_names_uniprotkb": "L-lactate dehydrogenase C chain; 1.1.1.27; LDH testis subunit; LDH-C; LDH-X", "protein_names_refseq": "L-lactate dehydrogenase C chain; LDH testis subunit", "tax_id": 9823, "disease": "", "pathway": " (ssc:100502559)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Possible role in sperm motility., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004459 L-lactate dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006089 lactate metabolic process;GO:0042867 pyruvate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9TSX5-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9TT01-1", "uniprot_id": [ { "id": "DMRT1_PIG", "url": "https://www.uniprot.org/uniprot/Q9TT01", "type": "external" } ], "mass": 39346.0, "length": 373, "protein_name": "Doublesex- and mab-3-related transcription factor 1", "gene_name": "DMRT1", "organism": "Pig", "refseq_name": "doublesex- and mab-3-related transcription factor 1", "refseq_ac": [ { "id": "NP_999276", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999276", "type": "external" } ], "gene_names_uniprotkb": "DMRT1", "gene_names_refseq": "DMRT-1; DMRT1", "protein_names_uniprotkb": "Doublesex- and mab-3-related transcription factor 1", "protein_names_refseq": "double-sex and mab-related transcription factor 1; doublesex- and mab-3-related transcription factor 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397199)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and promotes spermatogonial development by activating spermatogonial differentiation genes, such as SOHLH1. Also plays a key role in postnatal sex maintenance by maintaining testis determination and preventing feminization: represses transcription of female promoting genes such as FOXL2 and activates male-specific genes. May act as a tumor suppressor. May also play a minor role in oogenesis (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987 cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0046661 male sex differentiation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0008344 adult locomotory behavior", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9TT01-1", "record_type": "protein", "filter_code": "0000000.0000001.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9TT35-1", "uniprot_id": [ { "id": "THBG_PIG", "url": "https://www.uniprot.org/uniprot/Q9TT35", "type": "external" } ], "mass": 46215.0, "length": 412, "protein_name": "Thyroxine-binding globulin", "gene_name": "SERPINA7", "organism": "Pig", "refseq_name": "thyroxine-binding globulin precursor", "refseq_ac": [ { "id": "NP_999223", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999223", "type": "external" } ], "gene_names_uniprotkb": "SERPINA7; TBG", "gene_names_refseq": "SERPINA7; tbg", "protein_names_uniprotkb": "Thyroxine-binding globulin; Serpin A7; T4-binding globulin", "protein_names_refseq": "T4-binding globulin; serpin A7; thyroxine-binding globulin precursor; thyroxine-binding globulin", "tax_id": 9823, "disease": "", "pathway": " (ssc:397125)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11850119;15385420", "class_list": "", "function": "Major thyroid hormone transport protein in serum., [UniProtKB]; Polymorphism in exon 2 in thyroxine-binding globulin is a candidate for the causative variation affecting testis size in boars., [RefSeq, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "Q5QGZ0", "ec_number_list": [], "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9TT35-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9TT95-1", "uniprot_id": [ { "id": "GALP_PIG", "url": "https://www.uniprot.org/uniprot/Q9TT95", "type": "external" } ], "mass": 12681.0, "length": 120, "protein_name": "Galanin-like peptide", "gene_name": "GALP", "organism": "Pig", "refseq_name": "galanin-like peptide isoform 1 precursor", "refseq_ac": [ { "id": "NP_998990", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998990", "type": "external" } ], "gene_names_uniprotkb": "GALP", "gene_names_refseq": "GALP", "protein_names_uniprotkb": "Galanin-like peptide", "protein_names_refseq": "galanin-like peptide isoform 1 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:396772)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10601261;15099568;23224658", "class_list": "", "function": "2D-NMR and circular dichroism spectroscopy demonstrate that GALP does not adopt a preferred conformation in pure water alone, but shows characteristics of transient turn-like structures in two distinct regions, [RefSeq, PubMed]; Hypothalamic neuropeptide which binds to the G protein-coupled galanin receptors (GALR1, GALR2 and GALR3). Involved in a large number of putative physiological functions in CNS homeostatic processes, including the regulation of gonadotropin-releasing hormone secretion (By similarity)., [UniProtKB]; The association analysis with litter size traits showed that at both loci CC and GG genotypes were different for NBA for all parities in DIV pigs (P < 0.05). However, two SNPs were not in significant linkage disequilibrium, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005179 hormone activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0042595 behavioral response to starvation;GO:0007218 neuropeptide signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9TT95-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9TU18-1", "uniprot_id": [ { "id": "AGRP_PIG", "url": "https://www.uniprot.org/uniprot/Q9TU18", "type": "external" } ], "mass": 14681.0, "length": 134, "protein_name": "Agouti-related protein", "gene_name": "AGRP", "organism": "Pig", "refseq_name": "agouti-related protein precursor", "refseq_ac": [ { "id": "NP_001011693", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011693", "type": "external" } ], "gene_names_uniprotkb": "AGRP", "gene_names_refseq": "AGRP", "protein_names_uniprotkb": "Agouti-related protein", "protein_names_refseq": "agouti related protein homolog; agouti-related protein precursor; agouti-related protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:397275)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12019634", "class_list": "", "function": "Signaling protein that functions as an antagonist of melanocyte-stimulating-hormone receptors MC3R and MC4R by precluding agonist-induced signaling, thereby inhibiting cAMP production within the hypothalamus and adrenal gland. Involved in the control of feeding behavior via the central melanocortin system. Has very low activity towards MC5R. Also promotes endocytosis of MC3R and MC4R in an arrestin-dependent mechanism., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0048019 receptor antagonist activity;GO:0005184 neuropeptide hormone activity;GO:0031781 type 3 melanocortin receptor binding;GO:0031782 type 4 melanocortin receptor binding;GO:0070996 type 1 melanocortin receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005796 Golgi lumen", "go_biological_process": "GO:0032100 positive regulation of appetite;GO:0007218 neuropeptide signaling pathway;GO:0032098 regulation of appetite;GO:0008343 adult feeding behavior;GO:0009755 hormone-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9TU18-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9TVC1-1", "uniprot_id": [ { "id": "VATH_PIG", "url": "https://www.uniprot.org/uniprot/Q9TVC1", "type": "external" } ], "mass": 55850.0, "length": 483, "protein_name": "V-type proton ATPase subunit H", "gene_name": "ATP6V1H", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ATP6V1H", "gene_names_refseq": "", "protein_names_uniprotkb": "V-type proton ATPase subunit H; V-ATPase 50/57 kDa subunits; V-ATPase subunit H; Vacuolar proton pump subunit H; Vacuolar proton pump subunit SFD", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:397472)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "10051322", "class_list": "", "function": "Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it promotes acidification of the extracellular environment (By similarity). The V-ATPase complex also acts as an activator for mTORC1 on lysosomal membrane by promoting the guanine nucleotide exchange factor (GEF) of the Ragulator complex, thereby enabling mTORC1 recruitment (By similarity). Subunit H is essential for V-ATPase activity, but not for the assembly of the complex (By similarity). Involved in the endocytosis mediated by clathrin-coated pits, required for the formation of endosomes (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9XSM4;Q9XSM5", "ec_number_list": [], "go_molecular_function": "GO:0046961 proton-transporting ATPase activity, rotational mechanism", "go_cellular_component": "GO:0030665 clathrin-coated vesicle membrane;GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9TVC1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9XSD4-1", "uniprot_id": [ { "id": "PTAFR_PIG", "url": "https://www.uniprot.org/uniprot/Q9XSD4", "type": "external" } ], "mass": 39436.0, "length": 342, "protein_name": "Platelet-activating factor receptor", "gene_name": "PTAFR", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PTAFR; PAFR", "gene_names_refseq": "", "protein_names_uniprotkb": "Platelet-activating factor receptor; PAF-R; PAFr", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 4, "publication_id_list": "11916258;11943497;12420294;14703076", "class_list": "", "function": "Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. May have a role in peri-implantation development during pregnancy (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0045028 G protein-coupled purinergic nucleotide receptor activity;GO:0004992 platelet activating factor receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0006935 chemotaxis;GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9XSD4-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000010000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q9XSD9-1", "uniprot_id": [ { "id": "PGS2_PIG", "url": "https://www.uniprot.org/uniprot/Q9XSD9", "type": "external" } ], "mass": 39899.0, "length": 360, "protein_name": "Decorin", "gene_name": "DCN", "organism": "Pig", "refseq_name": "decorin precursor", "refseq_ac": [ { "id": "NP_999085", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999085", "type": "external" } ], "gene_names_uniprotkb": "DCN", "gene_names_refseq": "DCN", "protein_names_uniprotkb": "Decorin; Bone proteoglycan II; PG-S2", "protein_names_refseq": "PG-S2; bone proteoglycan II; decorin precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:396957)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21232885;24529131", "class_list": "", "function": "LDL electrostatic interactions with decorin and biglycan in the aortic valve leaflets and vascular wall is a major source of LDL retention., [RefSeq, PubMed]; May affect the rate of fibrils formation., [UniProtKB]; The expression of the DCN gene increased from gestational day 26 to 90 in both Yorkshire and Meishan pig placenta., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 3, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q9XSH4", "ec_number_list": [], "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9XSD9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A140TAK4-1", "uniprot_id": [ { "id": "A0A140TAK4_PIG", "url": "https://www.uniprot.org/uniprot/A0A140TAK4", "type": "external" } ], "mass": 36933.0, "length": 323, "protein_name": "Myeloid differentiation primary response protein MyD88", "gene_name": "MYD88", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "MYD88", "gene_names_refseq": "", "protein_names_uniprotkb": "Myeloid differentiation primary response protein MyD88", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1257604); (R-SSC-1810476); (R-SSC-209543); (R-SSC-3134963); (R-SSC-6811558); (R-SSC-9020702)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0035591 signaling adaptor activity;GO:0035325 Toll-like receptor binding;GO:0005149 interleukin-1 receptor binding;GO:0070976 TIR domain binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0031234 extrinsic component of cytoplasmic side of plasma membrane", "go_biological_process": "GO:0070498 interleukin-1-mediated signaling pathway;GO:0032747 positive regulation of interleukin-23 production;GO:0032740 positive regulation of interleukin-17 production;GO:0006954 inflammatory response;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140TAK4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A5G2QUW8-1", "uniprot_id": [ { "id": "A0A5G2QUW8_PIG", "url": "https://www.uniprot.org/uniprot/A0A5G2QUW8", "type": "external" } ], "mass": 67656.0, "length": 615, "protein_name": "Spastin", "gene_name": "SPAST", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SPAST; SPG4", "gene_names_refseq": "", "protein_names_uniprotkb": "Spastin; 5.6.1.1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-9668328)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. It is critical for the biogenesis and maintenance of complex microtubule arrays in axons, spindles and cilia. SPAST is involved in abscission step of cytokinesis and nuclear envelope reassembly during anaphase in cooperation with the ESCRT-III complex. Recruited at the midbody, probably by IST1, and participates in membrane fission during abscission together with the ESCRT-III complex. Recruited to the nuclear membrane by IST1 and mediates microtubule severing, promoting nuclear envelope sealing and mitotic spindle disassembly during late anaphase. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and endosome recycling. Recruited by IST1 to endosomes and regulates early endosomal tubulation and recycling by mediating microtubule severing. Probably plays a role in axon growth and the formation of axonal branches., [UniProtKB, HAMAP, UniProtKB, UniProtKB]; Involved in DNA double-strand break (DBS) repair via homologous recombination (HR). Recruited at DSB sites independently of BRCA2, RAD51 and RAD51 paralogs in a H2AX-dependent manner. May regulate osteoblast proliferation and differentiation. May play a role in the control of male meiosis dynamic., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008568 microtubule severing ATPase activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0008017 microtubule binding;GO:0048487 beta-tubulin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005768 endosome;GO:0005783 endoplasmic reticulum;GO:0005813 centrosome;GO:0005819 spindle", "go_biological_process": "GO:0007399 nervous system development;GO:0051013 microtubule severing;GO:0031117 positive regulation of microtubule depolymerization;GO:0007409 axonogenesis;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QUW8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A1S6M251-1", "uniprot_id": [ { "id": "B4GT5_PIG", "url": "https://www.uniprot.org/uniprot/A0A1S6M251", "type": "external" } ], "mass": 45046.0, "length": 388, "protein_name": "Beta-1,4-galactosyltransferase 5", "gene_name": "B4GALT5", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "B4GALT5", "gene_names_refseq": "", "protein_names_uniprotkb": "Beta-1,4-galactosyltransferase 5; 2.4.1.-; 2.4.1.274; Beta-1,4-GalT II; Beta-1,4-GalTase 5; Beta4Gal-T5; Glucosylceramide beta-1,4-galactosyltransferase; LacCer synthase; Lactosylceramide synthase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5; b4Gal-T5", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100522653); (R-SSC-2022854); (R-SSC-913709); (R-SSC-975577); (R-SSC-9840309)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "29546034", "class_list": "glycogene;glycosyltransferase", "function": "(Microbial infection) May play a role in the glycosylation of porcine reproductive and respiratory syndrome virus GP5 protein and may be involved in the regulation of viral proliferation., [UniProtKB, PubMed]; Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer) (By similarity). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (By similarity). Plays a role in the glycosylation of BMPR1A and regulation of its protein stability (By similarity). Essential for extraembryonic development during early embryogenesis (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 7, "predicted_n_glycosites": 7, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 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"0000000.0000101.100000.000000000000010000.0000000010000.001.11000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287B8N1-1", "uniprot_id": [ { "id": "A0A287B8N1_PIG", "url": "https://www.uniprot.org/uniprot/A0A287B8N1", "type": "external" } ], "mass": 93364.0, "length": 850, "protein_name": "ATP-dependent 6-phosphofructokinase", "gene_name": "PFKM", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PFKM", "gene_names_refseq": "", "protein_names_uniprotkb": "ATP-dependent 6-phosphofructokinase; 2.7.1.11; ATP-PFK; Phosphofructokinase; Phosphohexokinase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-70171)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB, UniProtKB, 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"biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0003872 6-phosphofructokinase activity;GO:0070095 fructose-6-phosphate binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005634 nucleus;GO:0016020 membrane;GO:0016324 apical plasma membrane;GO:0097228 sperm principal piece", "go_biological_process": "GO:0006002 fructose 6-phosphate metabolic process;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0046716 muscle cell cellular homeostasis;GO:0030388 fructose 1,6-bisphosphate metabolic process;GO:0061621 canonical glycolysis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287B8N1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZIP0-1", "uniprot_id": [ { "id": "A0A286ZIP0_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZIP0", "type": "external" } ], "mass": 55393.0, "length": 491, "protein_name": "E3 ubiquitin-protein ligase Mdm2", "gene_name": "MDM2", "organism": "Pig", "refseq_name": "E3 ubiquitin-protein ligase Mdm2 isoform X1", "refseq_ac": [ { "id": "XP_013853160", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013853160", "type": "external" } ], "gene_names_uniprotkb": "MDM2", "gene_names_refseq": "MDM2", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase Mdm2; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase Mdm2 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-3232142); (R-SSC-399719); (R-SSC-5689880); (R-SSC-6804756); (R-SSC-6804757); (R-SSC-6804760); (R-SSC-69541); (R-SSC-8941858); (R-SSC-9766229)", "pathway_count": 9, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", 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0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A286ZT85;A0A4X1W2F4", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0043021 ribonucleoprotein complex binding;GO:0031625 ubiquitin protein ligase binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016604 nuclear body;GO:0032991 protein-containing complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0043066 negative regulation of apoptotic process;GO:0045931 positive regulation of mitotic cell cycle;GO:1990000 amyloid fibril formation;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZIP0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, 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regulator activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0032991 protein-containing complex", "go_biological_process": "GO:0007165 signal transduction;GO:0051262 protein tetramerization;GO:0006915 apoptotic process;GO:0035556 intracellular signal transduction;GO:0043065 positive regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AUI9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZIV3-1", "uniprot_id": [ { "id": "A0A286ZIV3_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZIV3", "type": "external" } ], "mass": 94759.0, "length": 835, "protein_name": "DNA repair protein Ku80", "gene_name": "XRCC5", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "XRCC5", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA repair protein Ku80; 4.2.99.18; 5.6.2.4; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; DNA repair protein XRCC5; Ku80; Nuclear factor IV; X-ray repair cross-complementing protein 5", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5693571); (R-SSC-6798695)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0051575 5'-deoxyribose-5-phosphate lyase activity;GO:0005524 ATP binding;GO:0003684 damaged DNA binding;GO:0016887 ATP hydrolysis activity;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0032993 protein-DNA complex;GO:0005958 DNA-dependent protein kinase-DNA ligase 4 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"protein", "filter_code": "0000000.0000101.001000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZP67-1", "uniprot_id": [ { "id": "A0A286ZP67_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZP67", "type": "external" } ], "mass": 89061.0, "length": 806, "protein_name": "Heterogeneous nuclear ribonucleoprotein U", "gene_name": "HNRNPU", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "HNRNPU", "gene_names_refseq": "", "protein_names_uniprotkb": "Heterogeneous nuclear ribonucleoprotein U; Scaffold-attachment factor A", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-72163); (R-SSC-72203); (R-SSC-9770562)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, 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"A0A4X1SPV1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZL70-1", "uniprot_id": [ { "id": "A0A286ZL70_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZL70", "type": "external" } ], "mass": 110801.0, "length": 977, "protein_name": "Vacuolar protein sorting-associated protein 54", "gene_name": "VPS54", "organism": "Pig", "refseq_name": "vacuolar protein sorting-associated protein 54 isoform X1", "refseq_ac": [ { "id": "XP_020943117", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020943117", "type": "external" } ], "gene_names_uniprotkb": "VPS54", "gene_names_refseq": "VPS54", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 54", "protein_names_refseq": "vacuolar protein sorting-associated protein 54 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100621212); (R-SSC-6811440)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Acts as a component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Within the GARP complex, required to tether the complex to the TGN. 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2.7.10.2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1059683); (R-SSC-112411); (R-SSC-1169408); (R-SSC-1266695); (R-SSC-449836); (R-SSC-5673001); (R-SSC-5684996); (R-SSC-6783783); (R-SSC-6785807); (R-SSC-6788467); (R-SSC-877300); (R-SSC-877312); (R-SSC-8854691); (R-SSC-8983432); (R-SSC-8984722); (R-SSC-8985947); (R-SSC-9020558); (R-SSC-9020591); (R-SSC-9020956); (R-SSC-9020958); (R-SSC-909733); (R-SSC-912526); (R-SSC-912694); (R-SSC-9674555); (R-SSC-9705462); (R-SSC-9732724); (R-SSC-9931295); (R-SSC-9958825)", "pathway_count": 28, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Kinase partner for the type I interferon receptor IFNAR2. In response to interferon-binding to IFNAR1-IFNAR2 heterodimer, phosphorylates and activates its binding partner IFNAR2, creating docking sites for STAT proteins. Directly phosphorylates STAT proteins but also activates STAT signaling through the transactivation of other JAK kinases associated with signaling receptors., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0031625 ubiquitin protein ligase binding;GO:0019903 protein phosphatase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0031234 extrinsic component of cytoplasmic side of plasma membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0035771 interleukin-4-mediated signaling pathway;GO:0038110 interleukin-2-mediated signaling pathway;GO:1903672 positive regulation of sprouting angiogenesis;GO:0150105 protein localization to cell-cell junction;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZLI2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZLS5-1", "uniprot_id": [ { "id": "A0A286ZLS5_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZLS5", "type": "external" } ], "mass": 65400.0, "length": 572, "protein_name": "Protein kinase C", "gene_name": "PRKCI", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PRKCI", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein kinase C; 2.7.11.13", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1912408); (R-SSC-209543); (R-SSC-420029); (R-SSC-9755511)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0005543 phospholipid binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005903 brush border;GO:0016324 apical plasma membrane;GO:0043220 Schmidt-Lanterman incisure", "go_biological_process": "GO:0060252 positive regulation of glial cell proliferation;GO:0010976 positive regulation of neuron projection development;GO:0032869 cellular response to insulin stimulus;GO:0035556 intracellular signal transduction;GO:0072659 protein localization to plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZLS5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A480QH44-1", "uniprot_id": [ { "id": "A0A480QH44_PIG", "url": "https://www.uniprot.org/uniprot/A0A480QH44", "type": "external" } ], "mass": 332816.0, "length": 2983, "protein_name": "ATP-dependent chromatin remodeler CHD7", "gene_name": "CHD7", "organism": "Pig", "refseq_name": "chromodomain-helicase-DNA-binding protein 7 isoform X3", "refseq_ac": [ { "id": "XP_020944996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944996", "type": "external" } ], "gene_names_uniprotkb": "CHD7", "gene_names_refseq": "CHD7", "protein_names_uniprotkb": "ATP-dependent chromatin remodeler CHD7; Chromo domain-containing protein 7", "protein_names_refseq": "chromodomain-helicase-DNA-binding protein 7 isoform X3", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-9943962)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "ATP-dependent chromatin-remodeling factor, slides nucleosomes along DNA; nucleosome sliding requires ATP. Probable transcription regulator. May be involved in the in 45S precursor rRNA production., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "F1RT88", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0021545 cranial nerve development;GO:0043584 nose development;GO:0048806 genitalia development;GO:0060123 regulation of growth hormone secretion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A480QH44-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZM16-1", "uniprot_id": [ { "id": "A0A286ZM16_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZM16", "type": "external" } ], "mass": 63920.0, "length": 579, "protein_name": "Folliculin", "gene_name": "FLCN", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "FLCN", "gene_names_refseq": "", "protein_names_uniprotkb": "Folliculin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:110256140); (R-SSC-9639288)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004857 enzyme inhibitor activity;GO:0005096 GTPase activator activity;GO:0019899 enzyme binding;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005929 cilium;GO:0005765 lysosomal membrane", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:1901874 negative regulation of post-translational protein modification;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0035556 intracellular signal transduction;GO:0097009 energy homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZM16-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1TAC1-1", "uniprot_id": [ { "id": "A0A4X1TAC1_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1TAC1", "type": "external" } ], "mass": 46420.0, "length": 416, "protein_name": "Choline/ethanolaminephosphotransferase 1", "gene_name": "CEPT1", "organism": "Pig", "refseq_name": "choline/ethanolaminephosphotransferase 1 isoform X1", "refseq_ac": [ { "id": "XP_003125905", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003125905", "type": "external" } ], "gene_names_uniprotkb": "CEPT1", "gene_names_refseq": "CEPT1", "protein_names_uniprotkb": "Choline/ethanolaminephosphotransferase 1; 1-alkenyl-2-acylglycerol choline phosphotransferase; 2.7.8.1; 2.7.8.22; 2.7.8.2", "protein_names_refseq": "choline/ethanolaminephosphotransferase 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100154792); (R-SSC-1483191); (R-SSC-1483213)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP-ethanolamine, respectively. Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "I3LAL7", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004142 diacylglycerol cholinephosphotransferase activity;GO:0004307 ethanolaminephosphotransferase activity;GO:0047359 1-alkenyl-2-acylglycerol choline phosphotransferase activity", "go_cellular_component": "GO:0031965 nuclear membrane;GO:0005789 endoplasmic reticulum membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0006646 phosphatidylethanolamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A4X1TAC1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZMQ1-1", "uniprot_id": [ { "id": "A0A286ZMQ1_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZMQ1", "type": "external" } ], "mass": 52637.0, "length": 470, "protein_name": "5-hydroxytryptamine receptor 2A", "gene_name": "HTR2A", "organism": "Pig", "refseq_name": "5-hydroxytryptamine receptor 2A isoform X1", "refseq_ac": [ { "id": "XP_013835971", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013835971", "type": "external" } ], "gene_names_uniprotkb": "HTR2A", "gene_names_refseq": "5-HT2A; HTR2A", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 2A; 5-HT-2; Serotonin receptor 2A", "protein_names_refseq": "5-hydroxytryptamine receptor 2A isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-390666); (R-SSC-416476)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "G-protein coupled receptor for 5-hydroxytryptamine (serotonin)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0004993 G protein-coupled serotonin receptor activity;GO:0030594 neurotransmitter receptor activity;GO:0051378 serotonin binding;GO:0001587 Gq/11-coupled serotonin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0031410 cytoplasmic vesicle;GO:0005901 caveola", "go_biological_process": "GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0006874 intracellular calcium ion homeostasis;GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission;GO:0007210 serotonin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZMQ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZMU2-1", "uniprot_id": [ { "id": "A0A286ZMU2_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZMU2", "type": "external" } ], "mass": 105254.0, "length": 980, "protein_name": "Myocardin", "gene_name": "MYOCD", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "MYOCD", "gene_names_refseq": "", "protein_names_uniprotkb": "Myocardin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Smooth muscle cells (SM) and cardiac muscle cells-specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes. Plays a crucial role in cardiogenesis, urinary bladder development, and differentiation of the smooth muscle cell lineage (myogenesis). Positively regulates the transcription of genes involved in vascular smooth muscle contraction., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0042826 histone deacetylase binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070412 R-SMAD binding;GO:0035035 histone acetyltransferase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0035886 vascular associated smooth muscle cell differentiation;GO:0060379 cardiac muscle cell myoblast differentiation;GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045987 positive regulation of smooth muscle contraction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZMU2-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZNK4-1", "uniprot_id": [ { "id": "A0A286ZNK4_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZNK4", "type": "external" } ], "mass": 54435.0, "length": 504, "protein_name": "Transcriptional coactivator YAP1", "gene_name": "YAP1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "YAP1", "gene_names_refseq": "", "protein_names_uniprotkb": "Transcriptional coactivator YAP1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1251985); (R-SSC-2028269); (R-SSC-2032785); (R-SSC-8939236); (R-SSC-8951671); (R-SSC-9860927)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0003714 transcription corepressor activity;GO:0070064 proline-rich region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005923 bicellular tight junction", "go_biological_process": "GO:1902018 negative regulation of cilium assembly;GO:0061026 cardiac muscle tissue regeneration;GO:1904036 negative regulation of epithelial cell apoptotic process;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZNK4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZNP3-1", "uniprot_id": [ { "id": "A0A286ZNP3_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZNP3", "type": "external" } ], "mass": 63534.0, "length": 570, "protein_name": "Nuclear factor 1", "gene_name": "NFIB", "organism": "Pig", "refseq_name": "nuclear factor 1 B-type isoform X1", "refseq_ac": [ { "id": "XP_005660153", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005660153", "type": "external" } ], "gene_names_uniprotkb": "NFIB", "gene_names_refseq": "NFIB", "protein_names_uniprotkb": "Nuclear factor 1", "protein_names_refseq": "nuclear factor 1 B-type isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100155995)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0001650 fibrillar center;GO:0044300 cerebellar mossy fiber", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006260 DNA replication;GO:0002062 chondrocyte differentiation;GO:0060510 type II pneumocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZNP3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZNU0-1", "uniprot_id": [ { "id": "A0A286ZNU0_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZNU0", "type": "external" } ], "mass": 35806.0, "length": 311, "protein_name": "DNA polymerase", "gene_name": "POLB", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "POLB", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA polymerase; 2.7.7.7", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-110362); (R-SSC-110373); (R-SSC-110381); (R-SSC-5649702); (R-SSC-5651801); (R-SSC-5689880); (R-SSC-73930)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity., [UniProtKB, UniProtKB, UniProtKB]; Repair polymerase that plays a key role in base-excision repair. During this process, the damaged base is excised by specific DNA glycosylases, the DNA backbone is nicked at the abasic site by an apurinic/apyrimidic (AP) endonuclease, and POLB removes 5'-deoxyribose-phosphate from the preincised AP site acting as a 5'-deoxyribose-phosphate lyase (5'-dRP lyase); through its DNA polymerase activity, it adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. It is also able to cleave sugar-phosphate bonds 3' to an intact AP site, acting as an AP lyase., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0051575 5'-deoxyribose-5-phosphate lyase activity;GO:0003677 DNA binding;GO:0008017 microtubule binding;GO:0019899 enzyme binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005876 spindle microtubule;GO:0032991 protein-containing complex", "go_biological_process": "GO:0006284 base-excision repair;GO:0006260 DNA replication;GO:0006303 double-strand break repair via nonhomologous end joining;GO:0006281 DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZNU0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BIF3-1", "uniprot_id": [ { "id": "A0A287BIF3_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BIF3", "type": "external" } ], "mass": 63899.0, "length": 584, "protein_name": "Eyes absent homolog", "gene_name": "EYA1", "organism": "Pig", "refseq_name": "eyes absent homolog 1 isoform X8", "refseq_ac": [ { "id": "XP_020944908", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944908", "type": "external" } ], "gene_names_uniprotkb": "EYA1", "gene_names_refseq": "EYA1", "protein_names_uniprotkb": "Eyes absent homolog; 3.1.3.48", "protein_names_refseq": "eyes absent homolog 1 isoform X8", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5693565)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004725 protein tyrosine phosphatase activity;GO:0003723 RNA binding;GO:0140793 histone H2AXY142 phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016604 nuclear body;GO:0032993 protein-DNA complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0007501 mesodermal cell fate specification;GO:0016925 protein sumoylation;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BIF3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZPB0-1", "uniprot_id": [ { "id": "A0A286ZPB0_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZPB0", "type": "external" } ], "mass": 159858.0, "length": 1440, "protein_name": "Phospholipase B1, membrane-associated", "gene_name": "PLB1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PLB1", "gene_names_refseq": "", "protein_names_uniprotkb": "Phospholipase B1, membrane-associated; 3.1.1.3; 3.1.1.4; 3.1.1.5; Lysophospholipase; Phospholipase A2; Phospholipase B/lipase; Triacylglycerol lipase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1482788); (R-SSC-975634)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Calcium-independent membrane-associated phospholipase that catalyzes complete diacylation of phospholipids by hydrolyzing both sn-1 and sn-2 fatty acyl chains attached to the glycerol backbone (phospholipase B activity). Has dual phospholipase and lysophospholipase activities toward diacylphospholipids. Preferentially cleaves sn-2 ester bonds over sn-1 bonds. Acts as a lipase toward glycerolipid substrates. Hydrolyzes fatty acyl chains of diacylglycerols with preference for the sn-2 position and of triacylglycerols with not positional selectivity. May also hydrolyze long chain retinyl esters such as retinyl palmitate. May contribute to digestion of dietary phospholipids, glycerolipids and retinoids, facilitating lipid absorption at the brush border., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004622 phosphatidylcholine lysophospholipase activity;GO:0004623 phospholipase A2 activity;GO:0004806 triacylglycerol lipase activity;GO:0050253 retinyl-palmitate esterase activity", "go_cellular_component": "GO:0031526 brush border membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006644 phospholipid metabolic process;GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZPB0-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZPB7-1", "uniprot_id": [ { "id": "A0A286ZPB7_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZPB7", "type": "external" } ], "mass": 93066.0, "length": 822, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 16", "gene_name": "USP16", "organism": "Pig", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 16 isoform X2", "refseq_ac": [ { "id": "XP_005670374", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005670374", "type": "external" } ], "gene_names_uniprotkb": "USP16", "gene_names_refseq": "USP16", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 16; 3.4.19.12; Deubiquitinating enzyme 16; Ubiquitin thioesterase 16; Ubiquitin-specific-processing protease 16", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 16 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5689880)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB, UniProtKB]; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. Also deubiquitinates non-histone proteins, such as ribosomal protein RPS27A: deubiquitination of monoubiquitinated RPS27A promotes maturation of the 40S ribosomal subunit. Also mediates deubiquitination of tektin proteins (TEKT1, TEKT2, TEK3, TEKT4 and TEKT5), promoting their stability., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0043024 ribosomal small subunit binding;GO:0042393 histone binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006508 proteolysis;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051289 protein homotetramerization;GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZPB7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZWK2-1", "uniprot_id": [ { "id": "A0A286ZWK2_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZWK2", "type": "external" } ], "mass": 75924.0, "length": 693, "protein_name": "Heat shock protein family A (Hsp70) member 8", "gene_name": "HSPA8", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "HSPA8", "gene_names_refseq": "", "protein_names_uniprotkb": "Heat shock protein family A (Hsp70) member 8", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-3371453); (R-SSC-3371497); (R-SSC-3371568); (R-SSC-3371571); (R-SSC-450408); (R-SSC-6798695); (R-SSC-72163); (R-SSC-8856828); (R-SSC-8876725); (R-SSC-888590); (R-SSC-9833482)", "pathway_count": 11, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0055131 C3HC4-type RING finger domain binding;GO:0030674 protein-macromolecule adaptor activity;GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0044829 host-mediated activation of viral genome replication;GO:0061738 late endosomal microautophagy;GO:1902904 negative regulation of supramolecular fiber organization;GO:0030335 positive regulation of cell migration;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZWK2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZRD9-1", "uniprot_id": [ { "id": "A0A286ZRD9_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZRD9", "type": "external" } ], "mass": 431228.0, "length": 3967, "protein_name": "Histone-lysine N-methyltransferase", "gene_name": "KMT2A", "organism": "Pig", "refseq_name": "histone-lysine N-methyltransferase 2A isoform X4", "refseq_ac": [ { "id": "XP_020918573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020918573", "type": "external" } ], "gene_names_uniprotkb": "KMT2A", "gene_names_refseq": "KMT2A", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase; 2.1.1.364", "protein_names_refseq": "histone-lysine N-methyltransferase 2A isoform X4", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-3214841); (R-SSC-8936459); (R-SSC-8939236); (R-SSC-9772755); (R-SSC-9909649)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 8, "predicted_n_glycosites": 0, "predicted_o_glycosites": 8, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0042800 histone H3K4 methyltransferase activity;GO:0045322 unmethylated CpG binding", "go_cellular_component": "GO:0035097 histone methyltransferase complex;GO:0071339 MLL1 complex", "go_biological_process": "GO:0035162 embryonic hemopoiesis;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0090310 negative regulation of DNA methylation-dependent heterochromatin formation;GO:0045893 positive regulation of DNA-templated transcription;GO:0045815 transcription initiation-coupled chromatin remodeling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZRD9-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AVP0-1", "uniprot_id": [ { "id": "A0A287AVP0_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AVP0", "type": "external" } ], "mass": 64272.0, "length": 588, "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "organism": "Pig", "refseq_name": "myc box-dependent-interacting protein 1 isoform X3", "refseq_ac": [ { "id": "XP_020930116", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020930116", "type": "external" } ], "gene_names_uniprotkb": "BIN1", "gene_names_refseq": "BIN1", "protein_names_uniprotkb": "Myc box-dependent-interacting protein 1; Amphiphysin II; Amphiphysin-like protein; Bridging integrator 1", "protein_names_refseq": "myc box-dependent-interacting protein 1 isoform X3", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-8856828)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0002020 protease binding;GO:0005543 phospholipid binding;GO:0042802 identical protein binding;GO:0051015 actin filament binding;GO:0051087 protein-folding chaperone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005768 endosome;GO:0030424 axon;GO:0030315 T-tubule;GO:0005737 cytoplasm", "go_biological_process": "GO:0006897 endocytosis;GO:0030100 regulation of endocytosis;GO:0030154 cell differentiation;GO:0051649 establishment of localization in cell;GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AVP0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZS33-1", "uniprot_id": [ { "id": "A0A286ZS33_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZS33", "type": "external" } ], "mass": 204734.0, "length": 1845, "protein_name": "Breast cancer type 1 susceptibility protein homolog", "gene_name": "BRCA1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "BRCA1", "gene_names_refseq": "", "protein_names_uniprotkb": "Breast cancer type 1 susceptibility protein homolog; 2.3.2.27", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-3108214); (R-SSC-5685938); (R-SSC-5685942); (R-SSC-5689901); (R-SSC-5693537); (R-SSC-5693565); (R-SSC-5693568); (R-SSC-5693571); (R-SSC-5693579); (R-SSC-5693607); (R-SSC-5693616); (R-SSC-6804756); (R-SSC-69473)", "pathway_count": 13, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Regulates centrosomal microtubule nucleation. Required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. Required for FANCD2 targeting to sites of DNA damage. Inhibits lipid synthesis by binding to inactive phosphorylated ACACA and preventing its dephosphorylation. Contributes to homologous recombination repair (HRR) via its direct interaction with PALB2, fine-tunes recombinational repair partly through its modulatory role in the PALB2-dependent loading of BRCA2-RAD51 repair machinery at DNA breaks. Component of the BRCA1-RBBP8 complex which regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage via BRCA1-mediated ubiquitination of RBBP8. Acts as a transcriptional activator., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0003684 damaged DNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0016604 nuclear body;GO:0070531 BRCA1-A complex;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0007059 chromosome segregation;GO:0045717 negative regulation of fatty acid biosynthetic process;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0010575 positive regulation of vascular endothelial growth factor production;GO:0045766 positive regulation of angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZS33-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287ABK7-1", "uniprot_id": [ { "id": "A0A287ABK7_PIG", "url": "https://www.uniprot.org/uniprot/A0A287ABK7", "type": "external" } ], "mass": 171394.0, "length": 1532, "protein_name": "Multidrug resistance-associated protein 1", "gene_name": "ABCC1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ABCC1", "gene_names_refseq": "", "protein_names_uniprotkb": "Multidrug resistance-associated protein 1; 7.6.2.2; 7.6.2.3; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1660661); (R-SSC-189483); (R-SSC-2142691); (R-SSC-382556); (R-SSC-9707564); (R-SSC-9753281); (R-SSC-9758890)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008559 ABC-type xenobiotic transporter activity;GO:0016887 ATP hydrolysis activity;GO:0015431 ABC-type glutathione S-conjugate transporter activity;GO:0034040 ATPase-coupled lipid transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0030054 cell junction;GO:0016324 apical plasma membrane;GO:0016328 lateral plasma membrane", "go_biological_process": "GO:0006869 lipid transport;GO:0045332 phospholipid translocation;GO:0070633 transepithelial transport;GO:1990962 xenobiotic transport across blood-brain barrier;GO:0034775 glutathione transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287ABK7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A480YT82-1", "uniprot_id": [ { "id": "A0A480YT82_PIG", "url": "https://www.uniprot.org/uniprot/A0A480YT82", "type": "external" } ], "mass": 74671.0, "length": 661, "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "ACOX1", "organism": "Pig", "refseq_name": "peroxisomal acyl-coenzyme A oxidase 1 isoform X1", "refseq_ac": [ { "id": "XP_020921674", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921674", "type": "external" } ], "gene_names_uniprotkb": "ACOX1", "gene_names_refseq": "ACOX1; ACO", "protein_names_uniprotkb": "Acyl-coenzyme A oxidase", "protein_names_refseq": "peroxisomal acyl-coenzyme A oxidase 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2046106); (R-SSC-390247); (R-SSC-9033241)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Involved in the initial and rate-limiting step of peroxisomal beta-oxidation of straight-chain saturated and unsaturated very-long-chain fatty acids. Catalyzes the desaturation of fatty acyl-CoAs that have a saturated bond between C2 and C3 (2,3-saturated acyl-CoA) to 2-trans-enoyl-CoAs ((2E)-enoyl-CoAs), and donates electrons directly to molecular oxygen (O(2)), thereby producing hydrogen peroxide (H(2)O(2))., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, 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"secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0047522 15-oxoprostaglandin 13-reductase [NAD(P)+] activity;GO:0035798 2-alkenal reductase (NADPH) activity;GO:0032440 2-alkenal reductase [NAD(P)H] activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006693 prostaglandin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A5G5-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AT99-1", "uniprot_id": [ { "id": "A0A287AT99_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AT99", "type": "external" } ], "mass": 104531.0, "length": 925, "protein_name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1", "gene_name": "ENPP1", "organism": "Pig", "refseq_name": "ectonucleotide pyrophosphatase/phosphodiesterase family member 1 isoform X1", "refseq_ac": [ { "id": "XP_020943592", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020943592", "type": "external" } ], "gene_names_uniprotkb": "ENPP1", "gene_names_refseq": "ENPP1", "protein_names_uniprotkb": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1; 3.1.4.1; 3.6.1.9; Alkaline phosphodiesterase I; Nucleotide diphosphatase; Nucleotide pyrophosphatase; Phosphodiesterase I/nucleotide pyrophosphatase 1; Plasma-cell membrane glycoprotein PC-1", "protein_names_refseq": "ectonucleotide pyrophosphatase/phosphodiesterase family member 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100037271); (R-SSC-196843)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030247 polysaccharide binding;GO:0005044 scavenger receptor activity;GO:0046872 metal ion binding;GO:0003676 nucleic acid binding;GO:0004528 phosphodiesterase I activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0005615 extracellular space;GO:0009986 cell surface;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0006955 immune response;GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0006091 generation of precursor metabolites and energy;GO:0032869 cellular response to insulin stimulus;GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AT99-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1T9D7-1", "uniprot_id": [ { "id": "A0A4X1T9D7_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1T9D7", "type": "external" } ], "mass": 316150.0, "length": 2804, "protein_name": "Nipped-B protein", "gene_name": "NIPBL", "organism": "Pig", "refseq_name": "nipped-B-like protein isoform X1", "refseq_ac": [ { "id": "XP_013840191", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013840191", "type": "external" } ], "gene_names_uniprotkb": "NIPBL", "gene_names_refseq": "NIPBL", "protein_names_uniprotkb": "Nipped-B protein", "protein_names_refseq": "nipped-B-like protein isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100624231); (R-SSC-2470946)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays an important role in the loading of the cohesin complex on to DNA. Forms a heterodimeric complex (also known as cohesin loading complex) with MAU2/SCC4 which mediates the loading of the cohesin complex onto chromatin. Plays a role in cohesin loading at sites of DNA damage. Its recruitment to double-strand breaks (DSBs) sites occurs in a CBX3-, RNF8- and RNF168-dependent manner whereas its recruitment to UV irradiation-induced DNA damage sites occurs in a ATM-, ATR-, RNF8- and RNF168-dependent manner. Along with ZNF609, promotes cortical neuron migration during brain development by regulating the transcription of crucial genes in this process. Preferentially binds promoters containing paused RNA polymerase II. Up-regulates the expression of SEMA3A, NRP1, PLXND1 and GABBR2 genes, among others., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287BF39", "ec_number_list": [], "go_molecular_function": "GO:0061775 cohesin loader activity;GO:0003682 chromatin binding;GO:0003714 transcription corepressor activity;GO:0042826 histone deacetylase binding;GO:0070087 chromo shadow domain binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0000785 chromatin;GO:0032039 integrator complex;GO:0090694 Scc2-Scc4 cohesin loading complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007507 heart development;GO:0048638 regulation of developmental growth;GO:0010468 regulation of gene expression;GO:0048562 embryonic organ morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A4X1T9D7-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A649-1", "uniprot_id": [ { "id": "A0A287A649_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A649", "type": "external" } ], "mass": 19053.0, "length": 167, "protein_name": "Epithelial membrane protein 2", "gene_name": "EMP2", "organism": "Pig", "refseq_name": "epithelial membrane protein 2", "refseq_ac": [ { "id": "XP_020942299", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942299", "type": "external" } ], "gene_names_uniprotkb": "EMP2", "gene_names_refseq": "EMP2", "protein_names_uniprotkb": "Epithelial membrane protein 2", "protein_names_refseq": "epithelial membrane protein 2", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0019900 kinase binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0007015 actin filament organization;GO:0007155 cell adhesion;GO:0008284 positive regulation of cell population proliferation;GO:0072659 protein localization to plasma membrane;GO:0003093 regulation of glomerular filtration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A649-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A671-1", "uniprot_id": [ { "id": "A0A287A671_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A671", "type": "external" } ], "mass": 133796.0, "length": 1218, "protein_name": "Delta-like protein", "gene_name": "JAG1", "organism": "Pig", "refseq_name": "protein jagged-1 isoform X2", "refseq_ac": [ { "id": "XP_005672756", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005672756", "type": "external" } ], "gene_names_uniprotkb": "JAG1", "gene_names_refseq": "JAG1", "protein_names_uniprotkb": "Delta-like protein", "protein_names_refseq": "protein jagged-1 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100156773); (R-SSC-9013149); (R-SSC-9013423)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Putative Notch ligand involved in the mediation of Notch signaling., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "M3TYN3", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0005543 phospholipid binding;GO:0005509 calcium ion binding;GO:0005112 Notch binding", "go_cellular_component": "GO:0005912 adherens junction;GO:0016324 apical plasma membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0042491 inner ear auditory receptor cell differentiation;GO:0072070 loop of Henle development;GO:0007219 Notch signaling pathway;GO:0042127 regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A671-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A7S3-1", "uniprot_id": [ { "id": "A0A287A7S3_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A7S3", "type": "external" } ], "mass": 49396.0, "length": 461, "protein_name": "ERBB receptor feedback inhibitor 1", "gene_name": "ERRFI1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ERRFI1", "gene_names_refseq": "", "protein_names_uniprotkb": "ERBB receptor feedback inhibitor 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0048286 lung alveolus development;GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway;GO:0045616 regulation of keratinocyte differentiation;GO:0043589 skin morphogenesis;GO:0060426 lung vasculature development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A7S3-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A7V3-1", "uniprot_id": [ { "id": "A0A287A7V3_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A7V3", "type": "external" } ], "mass": 62598.0, "length": 545, "protein_name": "Beta-hexosaminidase", "gene_name": "HEXA", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "HEXA", "gene_names_refseq": "", "protein_names_uniprotkb": "Beta-hexosaminidase; 3.2.1.52", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2022857); (R-SSC-2024101); (R-SSC-2160916); (R-SSC-9840310)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides. The isozyme S is as active as the isozyme A on the anionic bis-sulfated glycans, the chondroitin-6-sulfate trisaccharide (C6S-3), and the dermatan sulfate pentasaccharide, and the sulfated glycosphingolipid SM2. The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide. Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0008375 acetylglucosaminyltransferase activity;GO:0004563 beta-N-acetylhexosaminidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0005764 lysosome;GO:0042582 azurophil granule", "go_biological_process": "GO:0006689 ganglioside catabolic process;GO:0030209 dermatan sulfate proteoglycan catabolic process;GO:0005975 carbohydrate metabolic process;GO:0006024 glycosaminoglycan biosynthetic process;GO:0030203 glycosaminoglycan metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287A7V3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287A9U9-1", "uniprot_id": [ { "id": "A0A287A9U9_PIG", "url": "https://www.uniprot.org/uniprot/A0A287A9U9", "type": "external" } ], "mass": 61282.0, "length": 555, "protein_name": "Solute carrier family 22 member 1", "gene_name": "SLC22A1", "organism": "Pig", "refseq_name": "solute carrier family 22 member 1", "refseq_ac": [ { "id": "NP_001335904", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335904", "type": "external" } ], "gene_names_uniprotkb": "SLC22A1", "gene_names_refseq": "OCT1; 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(R-SSC-4641262); (R-SSC-4641263)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in various processes including retinal angiogenesis and bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalosomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, 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"0000000.0000101.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287B7S0-1", "uniprot_id": [ { "id": "A0A287B7S0_PIG", "url": "https://www.uniprot.org/uniprot/A0A287B7S0", "type": "external" } ], "mass": 31936.0, "length": 285, "protein_name": "Ia antigen-associated invariant chain", "gene_name": "CD74", "organism": "Pig", "refseq_name": "CD74 antigen isoform X2", "refseq_ac": [ { "id": "XP_020935937", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020935937", "type": "external" } ], "gene_names_uniprotkb": "CD74", "gene_names_refseq": "CD74", "protein_names_uniprotkb": "Ia antigen-associated invariant chain", "protein_names_refseq": "CD74 antigen isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-202733); (R-SSC-2132295)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Binds to the peptide-binding site of MHC class II alpha/beta heterodimers forming 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"A0A287B7S0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287ABW3-1", "uniprot_id": [ { "id": "A0A287ABW3_PIG", "url": "https://www.uniprot.org/uniprot/A0A287ABW3", "type": "external" } ], "mass": 20697.0, "length": 184, "protein_name": "Gremlin", "gene_name": "GREM1", "organism": "Pig", "refseq_name": "gremlin-1 isoform X1", "refseq_ac": [ { "id": "XP_020953964", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020953964", "type": "external" } ], "gene_names_uniprotkb": "GREM1", "gene_names_refseq": "GREM1", "protein_names_uniprotkb": "Gremlin", "protein_names_refseq": "gremlin-1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100156280)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, 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10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0051015 actin filament binding;GO:0046332 SMAD binding;GO:0043539 protein serine/threonine kinase activator activity", "go_cellular_component": "GO:0042995 cell projection;GO:0070161 anchoring junction;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005912 adherens junction", "go_biological_process": "GO:0007155 cell adhesion;GO:0007229 integrin-mediated signaling pathway;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0043116 negative regulation of vascular permeability", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QJL5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287ADF0-1", "uniprot_id": [ { "id": "A0A287ADF0_PIG", "url": "https://www.uniprot.org/uniprot/A0A287ADF0", "type": "external" } ], "mass": 27424.0, "length": 240, "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PDGFB", "gene_names_refseq": "", "protein_names_uniprotkb": "Platelet-derived growth factor subunit B; PDGF-2; Platelet-derived growth factor B chain; Platelet-derived growth factor beta polypeptide", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-114608); (R-SSC-1257604); (R-SSC-186763); (R-SSC-186797); (R-SSC-5673001); (R-SSC-6811558)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005161 platelet-derived growth factor receptor binding;GO:0042056 chemoattractant activity;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0005518 collagen binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface;GO:0016020 membrane", "go_biological_process": "GO:0072126 positive regulation of glomerular mesangial cell proliferation;GO:1905064 negative regulation of vascular associated smooth muscle cell differentiation;GO:0001525 angiogenesis;GO:0008284 positive regulation of cell population proliferation;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287ADF0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BD80-1", "uniprot_id": [ { "id": "A0A287BD80_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BD80", "type": "external" } ], "mass": 90188.0, "length": 800, "protein_name": "protein-tyrosine-phosphatase", "gene_name": "PTPN22", "organism": "Pig", "refseq_name": "tyrosine-protein phosphatase non-receptor type 22 isoform X2", "refseq_ac": [ { "id": "XP_020946378", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020946378", "type": "external" } ], "gene_names_uniprotkb": "PTPN22", "gene_names_refseq": "PTPN22", "protein_names_uniprotkb": "protein-tyrosine-phosphatase; 3.1.3.48", "protein_names_refseq": "tyrosine-protein phosphatase non-receptor type 22 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-202427); (R-SSC-202430)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004726 non-membrane spanning protein tyrosine phosphatase activity;GO:0017124 SH3 domain binding;GO:0019900 kinase binding;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005634 nucleus;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0034141 positive regulation of toll-like receptor 3 signaling pathway;GO:0042307 positive regulation of protein import into nucleus;GO:0032727 positive regulation of interferon-alpha production;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0032715 negative regulation of interleukin-6 production", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BD80-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A480J4F4-1", "uniprot_id": [ { "id": "A0A480J4F4_PIG", "url": "https://www.uniprot.org/uniprot/A0A480J4F4", "type": "external" } ], "mass": 147750.0, "length": 1338, "protein_name": "Receptor protein-tyrosine kinase", "gene_name": "ERBB3", "organism": "Pig", "refseq_name": "receptor tyrosine-protein kinase erbB-3", "refseq_ac": [ { "id": "XP_020947458", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020947458", "type": "external" } ], "gene_names_uniprotkb": "ERBB3", "gene_names_refseq": "ERBB3", "protein_names_uniprotkb": "Receptor protein-tyrosine kinase; 2.7.10.1", "protein_names_refseq": "receptor tyrosine-protein kinase erbB-3", "tax_id": 9823, "disease": "", "pathway": " (ssc:100525045); (R-SSC-1227986); (R-SSC-1236394); (R-SSC-1250196); (R-SSC-1257604); (R-SSC-1306955); (R-SSC-1358803); (R-SSC-1963642); (R-SSC-5673001); (R-SSC-6785631); (R-SSC-6811558); (R-SSC-8847993); (R-SSC-8863795)", "pathway_count": 13, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "I3L6Z7", "ec_number_list": [], "go_molecular_function": "GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0038131 neuregulin receptor activity;GO:0038132 neuregulin binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0012505 endomembrane system;GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0050793 regulation of developmental process;GO:0030182 neuron differentiation;GO:0048468 cell development;GO:0007162 negative regulation of cell adhesion;GO:0007528 neuromuscular junction development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A480J4F4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287B1C5-1", "uniprot_id": [ { "id": "A0A287B1C5_PIG", "url": "https://www.uniprot.org/uniprot/A0A287B1C5", "type": "external" } ], "mass": 295101.0, "length": 2685, "protein_name": "Adenomatous polyposis coli protein", "gene_name": "APC", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "APC", "gene_names_refseq": "", "protein_names_uniprotkb": "Adenomatous polyposis coli protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-111465); (R-SSC-195253); (R-SSC-196299); (R-SSC-3769402); (R-SSC-4641262); (R-SSC-5689896)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Associates with both microtubules and actin filaments, components of the cytoskeleton. Plays a role in mediating the organization of F-actin into ordered bundles. Functions downstream of Rho GTPases and DIAPH1 to selectively stabilize microtubules. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A286ZSN0;F1RLG3", "ec_number_list": [], "go_molecular_function": "GO:0008017 microtubule binding;GO:0008013 beta-catenin binding;GO:0019901 protein kinase binding;GO:0031625 ubiquitin protein ligase binding;GO:0019887 protein kinase regulator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0071944 cell periphery;GO:0005634 nucleus;GO:0005813 centrosome;GO:0005874 microtubule", "go_biological_process": "GO:0016055 Wnt signaling pathway;GO:0030178 negative regulation of Wnt signaling pathway;GO:0001708 cell fate specification;GO:0007399 nervous system development;GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287B1C5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AEQ3-1", "uniprot_id": [ { "id": "A0A287AEQ3_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AEQ3", "type": "external" } ], "mass": 48913.0, "length": 468, "protein_name": "Forkhead box A1", "gene_name": "FOXA1", "organism": "Pig", "refseq_name": "hepatocyte nuclear factor 3-alpha", "refseq_ac": [ { "id": "XP_001929311", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929311", "type": "external" } ], "gene_names_uniprotkb": "FOXA1", "gene_names_refseq": "FOXA1", "protein_names_uniprotkb": "Forkhead box A1", "protein_names_refseq": "hepatocyte nuclear factor 3-alpha", "tax_id": 9823, "disease": "", "pathway": " (ssc:100156502); (R-SSC-9018519)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0019904 protein domain specific binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0001650 fibrillar center;GO:0005902 microvillus", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0043065 positive regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AEQ3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AET4-1", "uniprot_id": [ { "id": "A0A287AET4_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AET4", "type": "external" } ], "mass": 58843.0, "length": 538, "protein_name": "Natural resistance-associated macrophage protein 1", "gene_name": "SLC11A1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SLC11A1", "gene_names_refseq": "", "protein_names_uniprotkb": "Natural resistance-associated macrophage protein 1; Solute carrier family 11 member 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1222556); (R-SSC-425410); (R-SSC-6798695); (R-SSC-6803544)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Macrophage-specific antiporter that fluxes metal ions in either direction against a proton gradient. Localized to late endosomal lysosomal membranes, delivers bivalent cations from the cytosol into these acidic compartments where they may directly affect antimicrobial activity. Involved in iron metabolism and host natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0005384 manganese ion transmembrane transporter activity;GO:0051139 metal cation:proton antiporter activity;GO:0005381 iron ion transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0070821 tertiary granule membrane;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0030670 phagocytic vesicle membrane", "go_biological_process": "GO:0034755 iron ion transmembrane transport;GO:0006879 intracellular iron ion homeostasis;GO:0009617 response to bacterium;GO:0006828 manganese ion transport;GO:0030026 intracellular manganese ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AET4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AEZ4-1", "uniprot_id": [ { "id": "A0A287AEZ4_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AEZ4", "type": "external" } ], "mass": 245898.0, "length": 2350, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "WNK1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "WNK1", "gene_names_refseq": "", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", 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Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation. Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal neural stem cell proliferation in the hippocampus dentate gyrus. Required for normal progress through the cell cycle in neural progenitor cells, for self-renewal of neural stem cells, and for normal neuronal differentiation and maturation. 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Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells. Also binds the DEAR/FBXW7-AS1 receptor. Promotes mesenteric arterial wall remodeling via activation of ROCK signaling and subsequent colocalization of NFATC3 with F-actin filaments. 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(R-SSC-9013026); (R-SSC-9013106); (R-SSC-9013148); (R-SSC-9013149); (R-SSC-9013404); (R-SSC-9013423)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005096 GTPase activator activity;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0014069 postsynaptic density;GO:0016020 membrane", "go_biological_process": "GO:0030216 keratinocyte differentiation;GO:0002692 negative regulation of cellular extravasation;GO:0007264 small GTPase-mediated signal transduction;GO:0035023 regulation of Rho protein signal transduction;GO:0043114 regulation of vascular permeability", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AIC4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A480NH74-1", "uniprot_id": [ { "id": "A0A480NH74_PIG", "url": "https://www.uniprot.org/uniprot/A0A480NH74", "type": "external" } ], "mass": 43067.0, "length": 380, "protein_name": "Mitogen-activated protein kinase", "gene_name": "MAPK3", "organism": "Pig", "refseq_name": "mitogen-activated protein kinase 3", "refseq_ac": [ { "id": "XP_020943678", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020943678", "type": "external" } ], "gene_names_uniprotkb": "MAPK3", "gene_names_refseq": "MAPK3", "protein_names_uniprotkb": "Mitogen-activated protein kinase; 2.7.11.24", "protein_names_refseq": "mitogen-activated protein kinase 3", "tax_id": 9823, "disease": "", "pathway": " (ssc:445013); (R-SSC-112409); (R-SSC-1169408); (R-SSC-1181150); (R-SSC-1295596); (R-SSC-1502540); (R-SSC-162658); (R-SSC-170968); (R-SSC-198753); (R-SSC-202670); (R-SSC-2029482); (R-SSC-2173795); (R-SSC-2173796); (R-SSC-2559580); (R-SSC-2559582); (R-SSC-2559585); (R-SSC-2871796); (R-SSC-3371453); (R-SSC-375165); (R-SSC-450341); (R-SSC-456926); (R-SSC-5654726); (R-SSC-5654733); (R-SSC-5663213); (R-SSC-5668599); (R-SSC-5673001); (R-SSC-5674135); (R-SSC-5674499); (R-SSC-5675221); (R-SSC-6811558); (R-SSC-73728); (R-SSC-74749); (R-SSC-877300); (R-SSC-881907); (R-SSC-8939211); (R-SSC-9627069); (R-SSC-9732724); (R-SSC-982772); (R-SSC-9856649)", "pathway_count": 39, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0004707 MAP kinase activity;GO:0106310 protein serine kinase activity;GO:0001784 phosphotyrosine residue binding;GO:0004674 protein serine/threonine kinase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0005856 cytoskeleton;GO:0005925 focal adhesion;GO:0012505 endomembrane system", "go_biological_process": "GO:0009893 positive regulation of metabolic process;GO:0006915 apoptotic process;GO:1902531 regulation of intracellular signal transduction;GO:0010468 regulation of gene expression;GO:0051049 regulation of transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A480NH74-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287APC7-1", "uniprot_id": [ { "id": "A0A287APC7_PIG", "url": "https://www.uniprot.org/uniprot/A0A287APC7", "type": "external" } ], "mass": 129140.0, "length": 1171, "protein_name": "Calcium-transporting ATPase", "gene_name": "ATP2B4", "organism": "Pig", "refseq_name": "plasma membrane calcium-transporting ATPase 4 isoform X3", "refseq_ac": [ { "id": "XP_020918856", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020918856", "type": "external" } ], "gene_names_uniprotkb": "ATP2B4", "gene_names_refseq": "ATP2B4", "protein_names_uniprotkb": "Calcium-transporting ATPase; 7.2.2.10", "protein_names_refseq": "plasma membrane calcium-transporting ATPase 4 isoform X3", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-418359); (R-SSC-5578775); (R-SSC-936837)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the hydrolysis of ATP coupled with the transport of calcium., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1V4P0", "ec_number_list": [], "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0005388 P-type calcium transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0036126 sperm flagellum;GO:0045121 membrane raft;GO:0030018 Z disc;GO:0030315 T-tubule", "go_biological_process": "GO:0070885 negative regulation of calcineurin-NFAT signaling cascade;GO:0006357 regulation of transcription by RNA polymerase II;GO:0010629 negative regulation of gene expression;GO:0030317 flagellated sperm motility;GO:0051480 regulation of cytosolic calcium ion concentration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287APC7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AM88-1", "uniprot_id": [ { "id": "A0A287AM88_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AM88", "type": "external" } ], "mass": 84667.0, "length": 758, "protein_name": "Lysyl oxidase homolog", "gene_name": "LOXL2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LOXL2", "gene_names_refseq": "", "protein_names_uniprotkb": "Lysyl oxidase homolog; 1.4.3.13", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1566948); (R-SSC-2243919)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070492 oligosaccharide binding;GO:0005509 calcium ion binding;GO:0005507 copper ion binding;GO:0004720 protein-lysine 6-oxidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005654 nucleoplasm;GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0031012 extracellular matrix", "go_biological_process": "GO:1902455 negative regulation of stem cell population maintenance;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0001666 response to hypoxia;GO:0030199 collagen fibril organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AM88-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287B3D4-1", "uniprot_id": [ { "id": "A0A287B3D4_PIG", "url": "https://www.uniprot.org/uniprot/A0A287B3D4", "type": "external" } ], "mass": 139015.0, "length": 1277, "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "organism": "Pig", "refseq_name": "regulator of telomere elongation helicase 1 isoform X2", "refseq_ac": [ { "id": "XP_020934023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020934023", "type": "external" } ], "gene_names_uniprotkb": "RTEL1", "gene_names_refseq": "RTEL1", "protein_names_uniprotkb": "Regulator of telomere elongation helicase 1; 5.6.2.-", "protein_names_refseq": "regulator of telomere elongation helicase 1 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-171319); (R-SSC-174430)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "A probable ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0031965 nuclear membrane;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0090657 telomeric loop disassembly;GO:1904430 negative regulation of t-circle formation;GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0006260 DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287B3D4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287ANF9-1", "uniprot_id": [ { "id": "A0A287ANF9_PIG", "url": "https://www.uniprot.org/uniprot/A0A287ANF9", "type": "external" } ], "mass": 68949.0, "length": 600, "protein_name": "Prostaglandin G/H synthase 1", "gene_name": "PTGS1", "organism": "Pig", "refseq_name": "prostaglandin G/H synthase 1", "refseq_ac": [ { "id": "XP_001926164", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926164", "type": "external" } ], "gene_names_uniprotkb": "PTGS1", "gene_names_refseq": "PTGS1", "protein_names_uniprotkb": "Prostaglandin G/H synthase 1; 1.14.99.1; Cyclooxygenase-1; Prostaglandin H2 synthase 1; Prostaglandin-endoperoxide synthase 1", "protein_names_refseq": "prostaglandin G/H synthase 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397541); (R-SSC-140180); (R-SSC-2162123)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004666 prostaglandin-endoperoxide synthase activity;GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0004601 peroxidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005788 endoplasmic reticulum lumen;GO:0005789 endoplasmic reticulum membrane;GO:0043005 neuron projection;GO:0001750 photoreceptor outer segment", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0019371 cyclooxygenase pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287ANF9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287APJ6-1", "uniprot_id": [ { "id": "A0A287APJ6_PIG", "url": "https://www.uniprot.org/uniprot/A0A287APJ6", "type": "external" } ], "mass": 25936.0, "length": 238, "protein_name": "Apoptosis regulator Bcl-2", "gene_name": "KDSR", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "KDSR; BCL2", "gene_names_refseq": "", "protein_names_uniprotkb": "Apoptosis regulator Bcl-2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100049703); (R-SSC-111447); (R-SSC-111453)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). Also acts as an inhibitor of autophagy: interacts with BECN1 and AMBRA1 during non-starvation conditions and inhibits their autophagy function. May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0002020 protease binding;GO:0042802 identical protein binding;GO:0046982 protein heterodimerization activity;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005829 cytosol;GO:0031965 nuclear membrane;GO:0043209 myelin sheath;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0035094 response to nicotine;GO:0043065 positive regulation of apoptotic process;GO:0051607 defense response to virus;GO:0051881 regulation of mitochondrial membrane potential;GO:0030890 positive regulation of B cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287APJ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AQV4-1", "uniprot_id": [ { "id": "A0A287AQV4_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AQV4", "type": "external" } ], "mass": 65577.0, "length": 595, "protein_name": "Cystathionine beta-synthase", "gene_name": "CBS", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CBS", "gene_names_refseq": "", "protein_names_uniprotkb": "Cystathionine beta-synthase; 4.2.1.22", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1614603)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine. Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0031625 ubiquitin protein ligase binding;GO:0020037 heme binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0042262 DNA protection;GO:0043418 homocysteine catabolic process;GO:0006535 cysteine biosynthetic process from serine;GO:0006565 L-serine catabolic process;GO:0019343 cysteine biosynthetic process via cystathionine", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AQV4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287B660-1", "uniprot_id": [ { "id": "A0A287B660_PIG", "url": "https://www.uniprot.org/uniprot/A0A287B660", "type": "external" } ], "mass": 92141.0, "length": 842, "protein_name": "Glucocorticoid receptor", "gene_name": "NR3C1", "organism": "Pig", "refseq_name": "glucocorticoid receptor isoform X2", "refseq_ac": [ { "id": "XP_005653014", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005653014", "type": "external" } ], "gene_names_uniprotkb": "NR3C1", "gene_names_refseq": "GR; 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(R-SSC-3238698)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Ligand for members of the frizzled family of seven transmembrane receptors., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A480EWX3;A0A4X1TEB6", "ec_number_list": [], "go_molecular_function": "GO:0005109 frizzled binding;GO:0019904 protein domain specific binding;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0031012 extracellular matrix;GO:0098588 bounding membrane of organelle", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0000902 cell morphogenesis;GO:0030182 neuron differentiation;GO:0060070 canonical Wnt signaling pathway;GO:0045669 positive regulation of osteoblast differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AS32-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AT23-1", "uniprot_id": [ { "id": "A0A287AT23_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AT23", "type": "external" } ], "mass": 28678.0, "length": 271, "protein_name": "Aquaporin-1", "gene_name": "AQP1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AQP1", "gene_names_refseq": "", "protein_names_uniprotkb": "Aquaporin-1; Aquaporin-CHIP", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:407773); (R-SSC-1237044); (R-SSC-1247673); (R-SSC-432040); (R-SSC-432047)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Forms a water channel that facilitates the transport of water across cell membranes, playing a crucial role in water homeostasis in various tissues. Could also be permeable to small solutes including hydrogen peroxide, glycerol and gases such as amonnia (NH3), nitric oxide (NO) and carbon dioxide (CO2). Recruited to the ankyrin-1 complex, a multiprotein complex of the erythrocyte membrane, it could be part of a CO2 metabolon, linking facilitated diffusion of CO2 across the membrane, anion exchange of Cl(-)/HCO3(-) and interconversion of dissolved CO2 and carbonic acid in the cytosol. In vitro, it shows non-selective gated cation channel activity and may be permeable to cations like K(+) and Na(+) in vivo., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0046875 ephrin receptor binding;GO:0005267 potassium channel activity;GO:0015168 glycerol transmembrane transporter activity;GO:0015250 water channel activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016323 basolateral plasma membrane;GO:0030424 axon;GO:0031965 nuclear membrane;GO:0070062 extracellular exosome", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0050829 defense response to Gram-negative bacterium;GO:0071300 cellular response to retinoic acid;GO:0071320 cellular response to cAMP;GO:0045766 positive regulation of angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AT23-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AUT4-1", "uniprot_id": [ { "id": "A0A287AUT4_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AUT4", "type": "external" } ], "mass": 29510.0, "length": 280, "protein_name": "Hes family bHLH transcription factor 1", "gene_name": "HES1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "HES1", "gene_names_refseq": "", "protein_names_uniprotkb": "Hes family bHLH transcription factor 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0051087 protein-folding chaperone binding;GO:0042826 histone deacetylase binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0032991 protein-containing complex", "go_biological_process": "GO:2000981 negative regulation of inner ear receptor cell differentiation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007219 Notch signaling pathway;GO:0045665 negative regulation of neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AUT4-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AV88-1", "uniprot_id": [ { "id": "A0A287AV88_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AV88", "type": "external" } ], "mass": 20622.0, "length": 188, "protein_name": "Phospholipase A2", "gene_name": "PLA2G10", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PLA2G10", "gene_names_refseq": "", "protein_names_uniprotkb": "Phospholipase A2; 3.1.1.4", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1482788); (R-SSC-1482801); (R-SSC-1482839); (R-SSC-1482922); (R-SSC-1482925); (R-SSC-1483166)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, 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"go_biological_process": "GO:0046473 phosphatidic acid metabolic process;GO:0034638 phosphatidylcholine catabolic process;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0051247 positive regulation of protein metabolic process;GO:0051607 defense response to virus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AV88-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AVE0-1", "uniprot_id": [ { "id": "A0A287AVE0_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AVE0", "type": "external" } ], "mass": 40064.0, "length": 347, "protein_name": "Nodal growth differentiation factor", "gene_name": "NODAL", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "NODAL", "gene_names_refseq": "", "protein_names_uniprotkb": "Nodal growth differentiation factor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Essential for mesoderm formation and axial patterning during embryonic development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005125 cytokine activity;GO:0008083 growth factor activity;GO:0070698 type I activin receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0022409 positive regulation of cell-cell adhesion;GO:0003140 determination of left/right asymmetry in lateral mesoderm;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0070374 positive regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AVE0-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AVR3-1", "uniprot_id": [ { "id": "A0A287AVR3_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AVR3", "type": "external" } ], "mass": 98100.0, "length": 898, "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "NFKB1", "gene_names_refseq": "", "protein_names_uniprotkb": "Nuclear factor NF-kappa-B p105 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1169091); (R-SSC-1810476); (R-SSC-193692); (R-SSC-202424); (R-SSC-209560); (R-SSC-2871837); (R-SSC-3134963); (R-SSC-3214841); (R-SSC-445989); (R-SSC-448706); (R-SSC-5607764); (R-SSC-5621575); (R-SSC-5684264); (R-SSC-6798695); (R-SSC-9020702); (R-SSC-933542); (R-SSC-9860927); (R-SSC-9958825)", "pathway_count": 18, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Constitutes the active form, which associates with RELA/p65 to form the NF-kappa-B p65-p50 complex to form a transcription factor. Together with RELA/p65, binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of genes involved in immune response and acute phase reactions., [UniProtKB, UniProtKB]; P105 is the precursor of the active p50 subunit (Nuclear factor NF-kappa-B p50 subunit) of the nuclear factor NF-kappa-B. Acts as a cytoplasmic retention of attached NF-kappa-B proteins by p105., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0042802 identical protein binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0033256 I-kappaB/NF-kappaB complex;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0000785 chromatin;GO:0035525 NF-kappaB p50/p65 complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:1904385 cellular response to angiotensin;GO:0010957 negative regulation of vitamin D biosynthetic process;GO:0006351 DNA-templated transcription;GO:0007254 JNK cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AVR3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AVR4-1", "uniprot_id": [ { "id": "A0A287AVR4_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AVR4", "type": "external" } ], "mass": 55563.0, "length": 494, "protein_name": "Tyrosine 3-monooxygenase", "gene_name": "TH", "organism": "Pig", "refseq_name": "tyrosine 3-monooxygenase", "refseq_ac": [ { "id": "XP_020941111", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941111", "type": "external" } ], "gene_names_uniprotkb": "TH", "gene_names_refseq": "TH", "protein_names_uniprotkb": "Tyrosine 3-monooxygenase; 1.14.16.2; Tyrosine 3-hydroxylase", "protein_names_refseq": "tyrosine 3-monooxygenase", "tax_id": 9823, "disease": "", "pathway": " (ssc:110259705); (R-SSC-209905)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005506 iron ion binding;GO:0019899 enzyme binding;GO:0004511 tyrosine 3-monooxygenase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005790 smooth endoplasmic reticulum;GO:0030424 axon;GO:0043204 perikaryon", "go_biological_process": "GO:1990384 hyaloid vascular plexus regression;GO:0006585 dopamine biosynthetic process from tyrosine;GO:0007617 mating behavior;GO:0045471 response to ethanol;GO:0050890 cognition", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AVR4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AWF4-1", "uniprot_id": [ { "id": "A0A287AWF4_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AWF4", "type": "external" } ], "mass": 139914.0, "length": 1250, "protein_name": "Adenylate cyclase type 8", "gene_name": "ADCY8", "organism": "Pig", "refseq_name": "adenylate cyclase type 8 isoform X1", "refseq_ac": [ { "id": "XP_020944562", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944562", "type": "external" } ], "gene_names_uniprotkb": "ADCY8", "gene_names_refseq": "ADCY8", "protein_names_uniprotkb": "Adenylate cyclase type 8; 4.6.1.1", "protein_names_refseq": "adenylate cyclase type 8 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100622999); (R-SSC-163615); (R-SSC-170660); (R-SSC-170670); (R-SSC-418597); (R-SSC-5610787)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the formation of cAMP in response to calcium entry leadings to cAMP signaling activation that affect processes suche as synaptic plasticity and insulin secretion. Plays a role in many brain functions, such as learning, memory, drug addiction, and anxiety modulation through regulation of synaptic plasticity by modulating long-term memory and long-term potentiation (LTP) through CREB transcription factor activity modulation. Plays a central role in insulin secretion by controlling glucose homeostasis through glucagon-like peptide 1 and glucose signaling pathway and maintains insulin secretion through calcium-dependent PKA activation leading to vesicle pool replenishment. Also, allows PTGER3 to induce potentiation of PTGER4-mediated PLA2 secretion by switching from a negative to a positive regulation, during the IL1B induced-dedifferentiation of smooth muscle cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004016 adenylate cyclase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit;GO:0014069 postsynaptic density;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0006171 cAMP biosynthetic process;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007613 memory;GO:0007626 locomotory behavior;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AWF4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A5G2QWB2-1", "uniprot_id": [ { "id": "A0A5G2QWB2_PIG", "url": "https://www.uniprot.org/uniprot/A0A5G2QWB2", "type": "external" } ], "mass": 32883.0, "length": 287, "protein_name": "Heme oxygenase", "gene_name": "HMOX1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "HMOX1", "gene_names_refseq": "", "protein_names_uniprotkb": "Heme oxygenase; 1.14.14.18", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0004392 heme oxygenase (decyclizing) activity;GO:0042803 protein homodimerization activity;GO:0005198 structural molecule activity;GO:0020037 heme binding", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005634 nucleus;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0043922 host-mediated suppression of viral transcription;GO:1903901 negative regulation of viral life cycle;GO:0006788 heme oxidation;GO:0002246 wound healing involved in inflammatory response;GO:0006979 response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QWB2-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BHS8-1", "uniprot_id": [ { "id": "A0A287BHS8_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BHS8", "type": "external" } ], "mass": 41482.0, "length": 360, "protein_name": "Mitogen-activated protein kinase 14", "gene_name": "MAPK14", "organism": "Pig", "refseq_name": "mitogen-activated protein kinase 14 isoform X2", "refseq_ac": [ { "id": "XP_003356663", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003356663", "type": "external" } ], "gene_names_uniprotkb": "MAPK14", "gene_names_refseq": "MAPK14", "protein_names_uniprotkb": "Mitogen-activated protein kinase 14; 2.7.11.24; Mitogen-activated protein kinase p38 alpha", "protein_names_refseq": "mitogen-activated protein kinase 14 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-168638); (R-SSC-171007); (R-SSC-198753); (R-SSC-2559580); (R-SSC-418592); (R-SSC-432142); (R-SSC-4420097); (R-SSC-450302); (R-SSC-450341); (R-SSC-525793); (R-SSC-5668599); (R-SSC-6798695); (R-SSC-6804756); (R-SSC-69601); (R-SSC-9824585)", "pathway_count": 15, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A480WTV0", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0004707 MAP kinase activity;GO:0051525 NFAT protein binding;GO:0004674 protein serine/threonine kinase activity;GO:0048273 mitogen-activated protein kinase p38 binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0010831 positive regulation of myotube differentiation;GO:0030316 osteoclast differentiation;GO:0071493 cellular response to UV-B;GO:0090400 stress-induced premature senescence;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BHS8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AXH1-1", "uniprot_id": [ { "id": "A0A287AXH1_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AXH1", "type": "external" } ], "mass": 71318.0, "length": 656, "protein_name": "Sphingomyelin phosphodiesterase 3", "gene_name": "SMPD3", "organism": "Pig", "refseq_name": "sphingomyelin phosphodiesterase 3", "refseq_ac": [ { "id": "XP_005655834", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005655834", "type": "external" } ], "gene_names_uniprotkb": "SMPD3", "gene_names_refseq": "SMPD3", "protein_names_uniprotkb": "Sphingomyelin phosphodiesterase 3; 3.1.4.12; Neutral sphingomyelinase 2; Neutral sphingomyelinase II", "protein_names_refseq": "sphingomyelin phosphodiesterase 3", "tax_id": 9823, "disease": "", "pathway": " (ssc:100518128); (R-SSC-5626978); (R-SSC-9840310)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0001786 phosphatidylserine binding;GO:0004767 sphingomyelin phosphodiesterase activity;GO:0070300 phosphatidic acid binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane", "go_biological_process": "GO:0006685 sphingomyelin catabolic process;GO:0006684 sphingomyelin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AXH1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AXV6-1", "uniprot_id": [ { "id": "A0A287AXV6_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AXV6", "type": "external" } ], "mass": 31339.0, "length": 265, "protein_name": "Elongation of very long chain fatty acids protein 6", "gene_name": "ELOVL6", "organism": "Pig", "refseq_name": "elongation of very long chain fatty acids protein 6 isoform X1", "refseq_ac": [ { "id": "XP_020956364", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020956364", "type": "external" } ], "gene_names_uniprotkb": "ELOVL6", "gene_names_refseq": "ELOVL6", "protein_names_uniprotkb": "Elongation of very long chain fatty acids protein 6; 2.3.1.199; 3-keto acyl-CoA synthase ELOVL6; ELOVL FA elongase 6; ELOVL fatty acid elongase 6; Very long chain 3-ketoacyl-CoA synthase 6; Very long chain 3-oxoacyl-CoA synthase 6", "protein_names_refseq": "elongation of very long chain fatty acids protein 6 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100312970); (R-SSC-75876)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1UVT8", "ec_number_list": [], "go_molecular_function": "GO:0009922 fatty acid elongase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0009923 fatty acid elongase complex;GO:0016020 membrane", "go_biological_process": "GO:0030148 sphingolipid biosynthetic process;GO:0035338 long-chain fatty-acyl-CoA biosynthetic process;GO:0006636 unsaturated fatty acid biosynthetic process;GO:0034625 fatty acid elongation, monounsaturated fatty acid;GO:0034626 fatty acid elongation, polyunsaturated fatty acid", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AXV6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AYB4-1", "uniprot_id": [ { "id": "A0A287AYB4_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AYB4", "type": "external" } ], "mass": 122772.0, "length": 1088, "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PDGFRA", "gene_names_refseq": "", "protein_names_uniprotkb": "Platelet-derived growth factor receptor alpha; 2.7.10.1; Alpha platelet-derived growth factor receptor; Alpha-type platelet-derived growth factor receptor; PDGF-R-alpha; PDGFR-alpha", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1257604); (R-SSC-186763); (R-SSC-186797); (R-SSC-5673001); (R-SSC-6811558)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005161 platelet-derived growth factor receptor binding;GO:0005524 ATP binding;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005929 cilium;GO:0043235 receptor complex", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0008284 positive regulation of cell population proliferation;GO:0016477 cell migration;GO:0030335 positive regulation of cell migration;GO:0070374 positive regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AYB4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AYJ5-1", "uniprot_id": [ { "id": "A0A287AYJ5_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AYJ5", "type": "external" } ], "mass": 74188.0, "length": 675, "protein_name": "Growth arrest-specific protein 6", "gene_name": "GAS6", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "GAS6", "gene_names_refseq": "", "protein_names_uniprotkb": "Growth arrest-specific protein 6; AXL receptor tyrosine kinase ligand", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-114608); (R-SSC-159763); (R-SSC-159782); (R-SSC-202733); (R-SSC-381426); (R-SSC-8957275)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A5G2QMH2", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0005509 calcium ion binding;GO:0030971 receptor tyrosine kinase binding;GO:0001786 phosphatidylserine binding;GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0005576 extracellular region", "go_biological_process": "GO:0035457 cellular response to interferon-alpha;GO:0001961 positive regulation of cytokine-mediated signaling pathway;GO:0071307 cellular response to vitamin K;GO:0097241 hematopoietic stem cell migration to bone marrow;GO:1900142 negative regulation of oligodendrocyte apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AYJ5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AZ36-1", "uniprot_id": [ { "id": "A0A287AZ36_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AZ36", "type": "external" } ], "mass": 518982.0, "length": 4626, "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LRP2", "gene_names_refseq": "", "protein_names_uniprotkb": "Low-density lipoprotein receptor-related protein 2; Glycoprotein 330; Megalin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017124 SH3 domain binding;GO:0051087 protein-folding chaperone binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005905 clathrin-coated pit;GO:0030424 axon;GO:0030425 dendrite", "go_biological_process": "GO:0015031 protein transport;GO:0008584 male gonad development;GO:0001843 neural tube closure;GO:0030514 negative regulation of BMP signaling pathway;GO:0006898 receptor-mediated endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AZ36-1", "record_type": "protein", "filter_code": "0000000.0000100.000100.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AZ57-1", "uniprot_id": [ { "id": "A0A287AZ57_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AZ57", "type": "external" } ], "mass": 49124.0, "length": 478, "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "NUP62", "gene_names_refseq": "", "protein_names_uniprotkb": "Nuclear pore glycoprotein p62; 62 kDa nucleoporin; Nucleoporin Nup62", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-159227); (R-SSC-159230); (R-SSC-159231); (R-SSC-159236); (R-SSC-1855170); (R-SSC-1855196); (R-SSC-1855229); (R-SSC-191859); (R-SSC-3108214); (R-SSC-3232142); (R-SSC-3301854); (R-SSC-3371453); (R-SSC-4085377); (R-SSC-4551638); (R-SSC-4570464); (R-SSC-4615885)", "pathway_count": 16, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex. Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation. It might be involved in protein recruitment to the centrosome after nuclear breakdown., [UniProtKB, UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0051425 PTB domain binding;GO:0042169 SH2 domain binding;GO:0043130 ubiquitin binding;GO:0051879 Hsp90 protein binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0031965 nuclear membrane", "go_biological_process": "GO:0046601 positive regulation of centriole replication;GO:0046580 negative regulation of Ras protein signal transduction;GO:1903438 positive regulation of mitotic cytokinetic process;GO:0007166 cell surface receptor signaling pathway;GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AZ57-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AZD5-1", "uniprot_id": [ { "id": "A0A287AZD5_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AZD5", "type": "external" } ], "mass": 79104.0, "length": 708, "protein_name": "Matrix metalloproteinase-9", "gene_name": "MMP9", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "MMP9", "gene_names_refseq": "", "protein_names_uniprotkb": "Matrix metalloproteinase-9; 3.4.24.35; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1433557); (R-SSC-1442490); (R-SSC-1474228); (R-SSC-1592389); (R-SSC-3928665); (R-SSC-6798695); (R-SSC-9009391)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1U0W0", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0016477 cell migration;GO:0030198 extracellular matrix organization;GO:1904645 response to amyloid-beta;GO:0051549 positive regulation of keratinocyte migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AZD5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287AZH5-1", "uniprot_id": [ { "id": "A0A287AZH5_PIG", "url": "https://www.uniprot.org/uniprot/A0A287AZH5", "type": "external" } ], "mass": 47523.0, "length": 438, "protein_name": "Battenin", "gene_name": "CLN3", "organism": "Pig", "refseq_name": "battenin isoform X2", "refseq_ac": [ { "id": "XP_020941199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941199", "type": "external" } ], "gene_names_uniprotkb": "CLN3", "gene_names_refseq": "CLN3", "protein_names_uniprotkb": "Battenin", "protein_names_refseq": "battenin isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-9845576)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A481B6Y6", "ec_number_list": [], "go_molecular_function": "GO:0048306 calcium-dependent protein binding;GO:0120146 sulfatide binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0005829 cytosol;GO:0055037 recycling endosome;GO:0005764 lysosome", "go_biological_process": "GO:2001288 positive regulation of caveolin-mediated endocytosis;GO:0010762 regulation of fibroblast migration;GO:0046836 glycolipid transport;GO:0048172 regulation of short-term neuronal synaptic plasticity;GO:0007611 learning or memory", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287AZH5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A5G2QK59-1", "uniprot_id": [ { "id": "A0A5G2QK59_PIG", "url": "https://www.uniprot.org/uniprot/A0A5G2QK59", "type": "external" } ], "mass": 73363.0, "length": 656, "protein_name": "NFE2 like bZIP transcription factor 2", "gene_name": "NFE2L2", "organism": "Pig", "refseq_name": "nuclear factor erythroid 2-related factor 2 isoform X1", "refseq_ac": [ { "id": "XP_005672038", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005672038", "type": "external" } ], "gene_names_uniprotkb": "NFE2L2", "gene_names_refseq": "NFE2L2", "protein_names_uniprotkb": "NFE2 like bZIP transcription factor 2", "protein_names_refseq": "nuclear factor erythroid 2-related factor 2 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-8951664); (R-SSC-9755511); (R-SSC-9759194); (R-SSC-9762114)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, 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cytosol;GO:0000785 chromatin;GO:0032993 protein-DNA complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:1902037 negative regulation of hematopoietic stem cell differentiation;GO:1903788 positive regulation of glutathione biosynthetic process;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QK59-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287B1L8-1", "uniprot_id": [ { "id": "A0A287B1L8_PIG", "url": "https://www.uniprot.org/uniprot/A0A287B1L8", "type": "external" } ], "mass": 271827.0, "length": 2560, "protein_name": "Neurogenic locus notch homolog protein 1", "gene_name": "NOTCH1", "organism": "Pig", "refseq_name": "neurogenic locus notch homolog protein 1", "refseq_ac": [ { "id": "XP_020936696", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020936696", "type": "external" } ], "gene_names_uniprotkb": "NOTCH1", "gene_names_refseq": "NOTCH1", "protein_names_uniprotkb": "Neurogenic locus notch homolog protein 1", "protein_names_refseq": "neurogenic locus notch homolog protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:110258061)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0004857 enzyme inhibitor activity;GO:0004888 transmembrane signaling receptor activity;GO:0019899 enzyme binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005783 endoplasmic reticulum;GO:0005912 adherens junction;GO:0009986 cell surface", "go_biological_process": "GO:0046579 positive regulation of Ras protein signal transduction;GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis;GO:0003192 mitral valve formation;GO:0060379 cardiac muscle cell myoblast differentiation;GO:0071228 cellular response to tumor cell", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287B1L8-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287B2Q0-1", "uniprot_id": [ { "id": "A0A287B2Q0_PIG", "url": "https://www.uniprot.org/uniprot/A0A287B2Q0", "type": "external" } ], "mass": 92219.0, "length": 824, "protein_name": "Hypoxia-inducible factor 1-alpha", "gene_name": "HIF1A", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "HIF1A", "gene_names_refseq": "", "protein_names_uniprotkb": "Hypoxia-inducible factor 1-alpha", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1234158); (R-SSC-1234174); (R-SSC-1234176); (R-SSC-5689880); (R-SSC-8857538); (R-SSC-8951664)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0019904 protein domain specific binding;GO:0046982 protein heterodimerization activity;GO:0031625 ubiquitin protein ligase binding;GO:0042826 histone deacetylase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0031514 motile cilium;GO:0005667 transcription regulator complex", "go_biological_process": "GO:1903427 negative regulation of reactive oxygen species biosynthetic process;GO:0006110 regulation of glycolytic process;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287B2Q0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1VBA4-1", "uniprot_id": [ { "id": "A0A4X1VBA4_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1VBA4", "type": "external" } ], "mass": 45707.0, "length": 393, "protein_name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "gene_name": "NAPEPLD", "organism": "Pig", "refseq_name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D isoform X2", "refseq_ac": [ { "id": "XP_003130288", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130288", "type": "external" } ], "gene_names_uniprotkb": "NAPEPLD", "gene_names_refseq": "NAPEPLD", "protein_names_uniprotkb": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D; 3.1.4.54", "protein_names_refseq": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D isoform X2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100737731)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "D-type phospholipase that hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce bioactive N-acylethanolamines/fatty acid ethanolamides (NAEs/FAEs) and phosphatidic acid. Cleaves the terminal phosphodiester bond of diacyl- and alkenylacyl-NAPEs, primarily playing a role in the generation of long-chain saturated and monounsaturated NAEs in the brain. May control NAPE homeostasis in dopaminergic neuron membranes and regulate neuron survival, partly through RAC1 activation. As a regulator of lipid metabolism in the adipose tissue, mediates the crosstalk between adipocytes, gut microbiota and immune cells to control body temperature and weight. In particular, regulates energy homeostasis by promoting cold-induced brown or beige adipocyte differentiation program to generate heat from fatty acids and glucose. Has limited D-type phospholipase activity toward N-acyl lyso-NAPEs., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8W4FJX8", "ec_number_list": [], "go_molecular_function": "GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0032052 bile acid binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005635 nuclear envelope;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0043025 neuronal cell body", "go_biological_process": "GO:0070291 N-acylethanolamine metabolic process;GO:0001659 temperature homeostasis;GO:0009395 phospholipid catabolic process;GO:0050729 positive regulation of inflammatory response;GO:0090336 positive regulation of brown fat cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A4X1VBA4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A5G2QQH9-1", "uniprot_id": [ { "id": "A0A5G2QQH9_PIG", "url": "https://www.uniprot.org/uniprot/A0A5G2QQH9", "type": "external" } ], "mass": 43602.0, "length": 392, "protein_name": "NAD-dependent protein deacetylase sirtuin-2", "gene_name": "SIRT2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SIRT2", "gene_names_refseq": "", "protein_names_uniprotkb": "NAD-dependent protein deacetylase sirtuin-2; 2.3.1.286; NAD-dependent protein deacylase sirtuin-2; NAD-dependent protein defatty-acylase sirtuin-2; Regulatory protein SIR2 homolog 2; SIR2-like protein 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2995383)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0070403 NAD+ binding;GO:0034979 NAD-dependent protein lysine deacetylase activity;GO:0042903 tubulin deacetylase activity;GO:0140773 NAD-dependent protein demyristoylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005819 spindle;GO:0005874 microtubule;GO:0030426 growth cone;GO:0043209 myelin sheath", "go_biological_process": "GO:0051301 cell division;GO:0051239 regulation of multicellular organismal process;GO:0051093 negative regulation of developmental process;GO:0045836 positive regulation of meiotic nuclear division;GO:0061433 cellular response to caloric restriction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QQH9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287B4X9-1", "uniprot_id": [ { "id": "A0A287B4X9_PIG", "url": "https://www.uniprot.org/uniprot/A0A287B4X9", "type": "external" } ], "mass": 117146.0, "length": 1047, "protein_name": "Guanylate cyclase", "gene_name": "NPR2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "NPR2", "gene_names_refseq": "", "protein_names_uniprotkb": "Guanylate cyclase; 4.6.1.2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5578768)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004383 guanylate cyclase activity;GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005929 cilium;GO:0045202 synapse", "go_biological_process": "GO:0030540 female genitalia development;GO:0035483 gastric emptying;GO:0001964 startle response;GO:0060466 activation of meiosis involved in egg activation;GO:0001570 vasculogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287B4X9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BRT1-1", "uniprot_id": [ { "id": "A0A287BRT1_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BRT1", "type": "external" } ], "mass": 74894.0, "length": 668, "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "RIPK1", "gene_names_refseq": "", "protein_names_uniprotkb": "Receptor-interacting serine/threonine-protein kinase 1; 2.7.11.1; Cell death protein RIP; Receptor-interacting protein 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-140534); (R-SSC-2562578); (R-SSC-3295583); (R-SSC-3371378); (R-SSC-5213460); (R-SSC-5218900); (R-SSC-5357786); (R-SSC-5357905); (R-SSC-5357956); (R-SSC-5675482); (R-SSC-5689880); (R-SSC-5689896); (R-SSC-69416); (R-SSC-75893); (R-SSC-937041)", "pathway_count": 15, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0070513 death domain binding;GO:0042803 protein homodimerization activity;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0043235 receptor complex;GO:0097342 ripoptosome;GO:0031264 death-inducing signaling complex", "go_biological_process": "GO:0007165 signal transduction;GO:0070105 positive regulation of interleukin-6-mediated signaling pathway;GO:0006954 inflammatory response;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0046330 positive regulation of JNK cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BRT1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287B575-1", "uniprot_id": [ { "id": "A0A287B575_PIG", "url": "https://www.uniprot.org/uniprot/A0A287B575", "type": "external" } ], "mass": 59170.0, "length": 520, "protein_name": "Histone deacetylase 3", "gene_name": "HDAC3", "organism": "Pig", "refseq_name": "histone deacetylase 3 isoform X1", "refseq_ac": [ { "id": "XP_013850708", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013850708", "type": "external" } ], "gene_names_uniprotkb": "HDAC3", "gene_names_refseq": "HDAC3", "protein_names_uniprotkb": "Histone deacetylase 3; 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lipase", "gene_name": "LIPE", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LIPE", "gene_names_refseq": "", "protein_names_uniprotkb": "Hormone-sensitive lipase; 3.1.1.23; 3.1.1.79; Monoacylglycerol lipase LIPE; Retinyl ester hydrolase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Lipase with broad substrate specificity, catalyzing the hydrolysis of triacylglycerols (TAGs), diacylglycerols (DAGs), monoacylglycerols (MAGs), cholesteryl esters and retinyl esters. Shows a preferential hydrolysis of DAGs over TAGs and MAGs. Preferentially hydrolyzes fatty acid (FA) esters at the sn-3 position of the glycerol backbone in DAGs and FA esters at the sn-1 and sn-2 positions of the glycerol backbone in TAGs. Catalyzes the hydrolysis of 2-arachidonoylglycerol, an endocannabinoid and of 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004771 sterol ester esterase activity;GO:0047372 monoacylglycerol lipase activity;GO:0004806 triacylglycerol lipase activity;GO:0050253 retinyl-palmitate esterase activity;GO:0120516 diacylglycerol lipase activity", "go_cellular_component": "GO:0005811 lipid droplet;GO:0005829 cytosol;GO:0005901 caveola", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0019433 triglyceride catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BDE3-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BE69-1", "uniprot_id": [ { "id": "A0A287BE69_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BE69", "type": "external" } ], "mass": 52880.0, "length": 472, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "SMAD2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SMAD2", "gene_names_refseq": "", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070410 co-SMAD binding;GO:0003682 chromatin binding;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0000785 chromatin", "go_biological_process": "GO:0017015 regulation of transforming growth factor beta receptor signaling pathway;GO:0003140 determination of left/right asymmetry in lateral mesoderm;GO:0006351 DNA-templated transcription;GO:0010629 negative regulation of gene expression;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BE69-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BE97-1", "uniprot_id": [ { "id": "A0A287BE97_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BE97", "type": "external" } ], "mass": 41731.0, "length": 399, "protein_name": "Thyroid nuclear factor 1", "gene_name": "NKX2-1", "organism": "Pig", "refseq_name": "homeobox protein Nkx-2.1 isoform 1", "refseq_ac": [ { "id": "NP_001298115", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001298115", "type": "external" } ], "gene_names_uniprotkb": "NKX2-1", "gene_names_refseq": "NKX2-1; TTF1", "protein_names_uniprotkb": "Thyroid nuclear factor 1", "protein_names_refseq": "RNA polymerase I transcription termination factor; homeobox protein Nkx-2.1 isoform 1; thyroid transcription factor 1-like", "tax_id": 9823, "disease": "", "pathway": " (ssc:100154384)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019899 enzyme binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding;GO:0001161 intronic transcription regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0030878 thyroid gland development;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0010628 positive regulation of gene expression;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BE97-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BFL9-1", "uniprot_id": [ { "id": "A0A287BFL9_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BFL9", "type": "external" } ], "mass": 43437.0, "length": 394, "protein_name": "Vascular endothelial growth factor A", "gene_name": "VEGFA", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "VEGFA", "gene_names_refseq": "", "protein_names_uniprotkb": "Vascular endothelial growth factor A; Vascular permeability factor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-114608); (R-SSC-194313); (R-SSC-195399); (R-SSC-4420097); (R-SSC-5218921)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. Also binds the DEAR/FBXW7-AS1 receptor., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005161 platelet-derived growth factor receptor binding;GO:0043183 vascular endothelial growth factor receptor 1 binding;GO:0008201 heparin binding;GO:0042056 chemoattractant activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005912 adherens junction;GO:0009986 cell surface;GO:0016020 membrane", "go_biological_process": "GO:1903672 positive regulation of sprouting angiogenesis;GO:0097533 cellular stress response to acid chemical;GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway;GO:0097475 motor neuron migration;GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BFL9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BFQ6-1", "uniprot_id": [ { "id": "A0A287BFQ6_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BFQ6", "type": "external" } ], "mass": 93422.0, "length": 843, "protein_name": "Axin 2", "gene_name": "AXIN2", "organism": "Pig", "refseq_name": "axin-2 isoform X1", "refseq_ac": [ { "id": "XP_020922392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020922392", "type": "external" } ], "gene_names_uniprotkb": "AXIN2", "gene_names_refseq": "AXIN2", "protein_names_uniprotkb": "Axin 2", "protein_names_refseq": "axin-2 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100739604); (R-SSC-4641257)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0019901 protein kinase binding;GO:0031625 ubiquitin protein ligase binding;GO:0008013 beta-catenin binding;GO:0070411 I-SMAD binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0030877 beta-catenin destruction complex", "go_biological_process": "GO:0048255 mRNA stabilization;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:1903053 regulation of extracellular matrix organization;GO:0008104 intracellular protein localization;GO:0042476 odontogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BFQ6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BGG6-1", "uniprot_id": [ { "id": "A0A287BGG6_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BGG6", "type": "external" } ], "mass": 34992.0, "length": 303, "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "organism": "Pig", "refseq_name": "E3 ubiquitin-protein ligase CHIP", "refseq_ac": [ { "id": "XP_003124756", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003124756", "type": "external" } ], "gene_names_uniprotkb": "STUB1", "gene_names_refseq": "STUB1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase CHIP; 2.3.2.27; Carboxy terminus of Hsp70-interacting protein; RING-type E3 ubiquitin transferase CHIP; STIP1 homology and U box-containing protein 1", "protein_names_refseq": "E3 ubiquitin-protein ligase CHIP", "tax_id": 9823, "disease": "", "pathway": " (ssc:100511251); (R-SSC-2173788); (R-SSC-5357905); (R-SSC-5675482); (R-SSC-8863795); (R-SSC-8939902); (R-SSC-8948751); (R-SSC-983168)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030911 TPR domain binding;GO:0042803 protein homodimerization activity;GO:0051087 protein-folding chaperone binding;GO:0001664 G protein-coupled receptor binding;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol", "go_biological_process": "GO:0031943 regulation of glucocorticoid metabolic process;GO:0090035 positive regulation of chaperone-mediated protein complex assembly;GO:0006281 DNA repair;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0050821 protein stabilization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BGG6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BIH8-1", "uniprot_id": [ { "id": "A0A287BIH8_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BIH8", "type": "external" } ], "mass": 51744.0, "length": 448, "protein_name": "Beclin-1", "gene_name": "BECN1", "organism": "Pig", "refseq_name": "beclin-1 isoform X1", "refseq_ac": [ { "id": "XP_013836386", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013836386", "type": "external" } ], "gene_names_uniprotkb": "BECN1", "gene_names_refseq": "ATG6; BECN1", "protein_names_uniprotkb": "Beclin-1", "protein_names_refseq": "beclin-1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1169408); (R-SSC-1632852); (R-SSC-5689880)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Beclin-1-C 35 kDa localized to mitochondria can promote apoptosis; it induces the mitochondrial translocation of BAX and the release of proapoptotic factors., [UniProtKB, UniProtKB]; Plays a central role in autophagy. Acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abscission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis. May play a role in antiviral host defense., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1TXX7", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0030674 protein-macromolecule adaptor activity;GO:0042802 identical protein binding;GO:0031625 ubiquitin protein ligase binding;GO:0051020 GTPase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane;GO:0016604 nuclear body;GO:0010008 endosome membrane;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0097352 autophagosome maturation;GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process;GO:0000045 autophagosome assembly;GO:0051301 cell division;GO:0051607 defense response to virus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BIH8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BIL8-1", "uniprot_id": [ { "id": "A0A287BIL8_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BIL8", "type": "external" } ], "mass": 73009.0, "length": 657, "protein_name": "Endoplasmic reticulum chaperone BIP", "gene_name": "HSPA5", "organism": "Pig", "refseq_name": "78 kDa glucose-regulated protein isoform X1", "refseq_ac": [ { "id": "XP_020924489", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020924489", "type": "external" } ], "gene_names_uniprotkb": "HSPA5", "gene_names_refseq": "HSPA5", "protein_names_uniprotkb": "Endoplasmic reticulum chaperone BIP; 3.6.4.10; 78 kDa glucose-regulated protein; Binding-immunoglobulin protein; Endoplasmic reticulum chaperone BiP; Heat shock protein 70 family protein 5; Heat shock protein family A member 5; Immunoglobulin heavy chain-binding protein", "protein_names_refseq": "78 kDa glucose-regulated protein isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-3371453); (R-SSC-983170); (R-SSC-9909505)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0019904 protein domain specific binding;GO:0016887 ATP hydrolysis activity;GO:0031072 heat shock protein binding;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0034663 endoplasmic reticulum chaperone complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005788 endoplasmic reticulum lumen", "go_biological_process": "GO:1903894 regulation of IRE1-mediated unfolded protein response;GO:0030335 positive regulation of cell migration;GO:0036498 IRE1-mediated unfolded protein response;GO:0043066 negative regulation of apoptotic process;GO:0031398 positive regulation of protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BIL8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1UCH0-1", "uniprot_id": [ { "id": "A0A4X1UCH0_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1UCH0", "type": "external" } ], "mass": 46670.0, "length": 410, "protein_name": "Platelet-activating factor acetylhydrolase IB subunit alpha", "gene_name": "PAFAH1B1", "organism": "Pig", "refseq_name": "platelet-activating factor acetylhydrolase IB subunit alpha isoform X1", "refseq_ac": [ { "id": "XP_005657074", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005657074", "type": "external" } ], "gene_names_uniprotkb": "PAFAH1B1; LIS1", "gene_names_refseq": "PAFAH1B1", "protein_names_uniprotkb": "Platelet-activating factor acetylhydrolase IB subunit alpha; LIS-1; Lissencephaly-1 protein; PAF acetylhydrolase 45 kDa subunit; PAF-AH 45 kDa subunit; PAF-AH alpha; PAFAH alpha", "protein_names_refseq": "platelet-activating factor acetylhydrolase IB subunit alpha isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-141430); (R-SSC-141444); (R-SSC-2467813); (R-SSC-2500257); (R-SSC-2565942); (R-SSC-380259); (R-SSC-380270); (R-SSC-380284); (R-SSC-380320); (R-SSC-5620912); (R-SSC-5663220); (R-SSC-6811436); (R-SSC-68877); (R-SSC-8854518); (R-SSC-9648025)", "pathway_count": 15, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Neuronal migration involves a process called nucleokinesis, whereby migrating cells extend an anterior process into which the nucleus subsequently translocates. During nucleokinesis dynein at the nuclear surface may translocate the nucleus towards the centrosome by exerting force on centrosomal microtubules. Also required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors. May also play a role in other forms of cell locomotion including the migration of fibroblasts during wound healing. Non-catalytic subunit of an acetylhydrolase complex which inactivates platelet-activating factor (PAF) by removing the acetyl group at the SN-2 position., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A480UJL5", "ec_number_list": [], "go_molecular_function": "GO:0016787 hydrolase activity;GO:0042802 identical protein binding;GO:0051219 phosphoprotein binding;GO:0051010 microtubule plus-end binding;GO:0070840 dynein complex binding", "go_cellular_component": "GO:0005874 microtubule;GO:0098978 glutamatergic synapse;GO:0000235 astral microtubule;GO:0005635 nuclear envelope;GO:0005813 centrosome", "go_biological_process": "GO:0007399 nervous system development;GO:0051301 cell division;GO:0008090 retrograde axonal transport;GO:0008344 adult locomotory behavior;GO:0050885 neuromuscular process controlling balance", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A4X1UCH0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BK75-1", "uniprot_id": [ { "id": "A0A287BK75_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BK75", "type": "external" } ], "mass": 43439.0, "length": 393, "protein_name": "Dual specificity mitogen-activated protein kinase kinase 1", "gene_name": "MAP2K1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "MAP2K1", "gene_names_refseq": "", "protein_names_uniprotkb": "Dual specificity mitogen-activated protein kinase kinase 1; 2.7.12.2; ERK activator kinase 1; MAPK/ERK kinase 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0097110 scaffold protein binding;GO:0005078 MAP-kinase scaffold activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005769 early endosome;GO:0005783 endoplasmic reticulum;GO:0005813 centrosome", "go_biological_process": "GO:2000641 regulation of early endosome to late endosome transport;GO:0007528 neuromuscular junction development;GO:0008285 negative regulation of cell population proliferation;GO:0010628 positive regulation of gene expression;GO:0070374 positive regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BK75-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BKC6-1", "uniprot_id": [ { "id": "A0A287BKC6_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BKC6", "type": "external" } ], "mass": 23696.0, "length": 217, "protein_name": "Heart- and neural crest derivatives-expressed protein 2", "gene_name": "HAND2", "organism": "Pig", "refseq_name": "heart- and neural crest derivatives-expressed protein 2", "refseq_ac": [ { "id": "XP_013838152", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013838152", "type": "external" } ], "gene_names_uniprotkb": "HAND2", "gene_names_refseq": "HAND2", "protein_names_uniprotkb": "Heart- and neural crest derivatives-expressed protein 2; Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2", "protein_names_refseq": "heart- and neural crest derivatives-expressed protein 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100153751)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003680 minor groove of adenine-thymine-rich DNA binding;GO:0042803 protein homodimerization activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007507 heart development;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BKC6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BLE1-1", "uniprot_id": [ { "id": "A0A287BLE1_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BLE1", "type": "external" } ], "mass": 47788.0, "length": 440, "protein_name": "Sequestosome-1", "gene_name": "SQSTM1", "organism": "Pig", "refseq_name": "sequestosome-1 isoform X1", "refseq_ac": [ { "id": "XP_003123687", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003123687", "type": "external" } ], "gene_names_uniprotkb": "SQSTM1", "gene_names_refseq": "SQSTM1", "protein_names_uniprotkb": "Sequestosome-1; Ubiquitin-binding protein p62", "protein_names_refseq": "sequestosome-1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100518718); (R-SSC-209543); (R-SSC-209560); (R-SSC-5205685); (R-SSC-9020702); (R-SSC-9664873); (R-SSC-9755511)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0140036 ubiquitin-modified protein reader activity;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0031625 ubiquitin protein ligase binding;GO:0005080 protein kinase C binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0005770 late endosome;GO:0030017 sarcomere", "go_biological_process": "GO:0001659 temperature homeostasis;GO:0030154 cell differentiation;GO:1900273 positive regulation of long-term synaptic potentiation;GO:0006915 apoptotic process;GO:0097009 energy homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BLE1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BLR9-1", "uniprot_id": [ { "id": "A0A287BLR9_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BLR9", "type": "external" } ], "mass": 52637.0, "length": 469, "protein_name": "TGF-beta receptor type-1", "gene_name": "TGFBR1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TGFBR1", "gene_names_refseq": "", "protein_names_uniprotkb": "TGF-beta receptor type-1; 2.7.11.30; TGF-beta type I receptor; Transforming growth factor-beta receptor type I", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2173788); (R-SSC-2173789); (R-SSC-2173791); (R-SSC-5689880); (R-SSC-9839389)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0031625 ubiquitin protein ligase binding;GO:0005025 transforming growth factor beta receptor activity, type I;GO:0016361 activin receptor activity, type I", "go_cellular_component": "GO:0005634 nucleus;GO:0005768 endosome;GO:0005886 plasma membrane;GO:0005923 bicellular tight junction;GO:0009986 cell surface", "go_biological_process": "GO:0007399 nervous system development;GO:0007507 heart development;GO:0010628 positive regulation of gene expression;GO:0030307 positive regulation of cell growth;GO:0030335 positive regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BLR9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BM29-1", "uniprot_id": [ { "id": "A0A287BM29_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BM29", "type": "external" } ], "mass": 44856.0, "length": 392, "protein_name": "Apolipoprotein A-IV", "gene_name": "APOA4", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "APOA4", "gene_names_refseq": "", "protein_names_uniprotkb": "Apolipoprotein A-IV; Apolipoprotein A4", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-8963888); (R-SSC-8963901); (R-SSC-975634)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005543 phospholipid binding;GO:0042803 protein homodimerization activity;GO:0016209 antioxidant activity;GO:0005507 copper ion binding;GO:0031210 phosphatidylcholine binding", "go_cellular_component": "GO:0009986 cell surface;GO:0034364 high-density lipoprotein particle;GO:0034361 very-low-density lipoprotein particle;GO:0042627 chylomicron;GO:0034362 low-density lipoprotein particle", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0010898 positive regulation of triglyceride catabolic process;GO:0033700 phospholipid efflux;GO:0042157 lipoprotein metabolic process;GO:0016042 lipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BM29-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BMD1-1", "uniprot_id": [ { "id": "A0A287BMD1_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BMD1", "type": "external" } ], "mass": 131917.0, "length": 1192, "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "RC3H2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "RC3H2", "gene_names_refseq": "", "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003729 mRNA binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0003725 double-stranded RNA binding", "go_cellular_component": "GO:0009986 cell surface;GO:0016020 membrane;GO:0000932 P-body;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:2000320 negative regulation of T-helper 17 cell differentiation;GO:0050852 T cell receptor signaling pathway;GO:0000209 protein polyubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:2000628 regulation of miRNA metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BMD1-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1UI98-1", "uniprot_id": [ { "id": "A0A4X1UI98_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1UI98", "type": "external" } ], "mass": 54627.0, "length": 505, "protein_name": "Cyclic AMP-dependent transcription factor ATF-2", "gene_name": "ATF2", "organism": "Pig", "refseq_name": "cyclic AMP-dependent transcription factor ATF-2 isoform X1", "refseq_ac": [ { "id": "XP_020931584", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020931584", "type": "external" } ], "gene_names_uniprotkb": "ATF2", "gene_names_refseq": "ATF2", "protein_names_uniprotkb": "Cyclic AMP-dependent transcription factor ATF-2", "protein_names_refseq": "cyclic AMP-dependent transcription factor ATF-2 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100513441); (R-SSC-3214847); (R-SSC-450341); (R-SSC-9018519)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA-3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA-3')., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A480K1R6;F1RZI1", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005741 mitochondrial outer membrane;GO:0035861 site of double-strand break;GO:1902562 H4 histone acetyltransferase complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0003360 brainstem development;GO:0021754 facial nucleus development;GO:0001701 in utero embryonic development;GO:0001889 liver development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A4X1UI98-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BML5-1", "uniprot_id": [ { "id": "A0A287BML5_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BML5", "type": "external" } ], "mass": 27830.0, "length": 247, "protein_name": "Homeobox protein Nkx-3.1", "gene_name": "NKX3-1", "organism": "Pig", "refseq_name": "homeobox protein Nkx-3.1", "refseq_ac": [ { "id": "XP_003483439", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003483439", "type": "external" } ], "gene_names_uniprotkb": "NKX3-1", "gene_names_refseq": "NKX3-1", "protein_names_uniprotkb": "Homeobox protein Nkx-3.1; Homeobox protein NK-3 homolog A", "protein_names_refseq": "homeobox protein Nkx-3.1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100738625)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042826 histone deacetylase binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0004879 nuclear receptor activity;GO:0030331 nuclear estrogen receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0090734 site of DNA damage", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007507 heart development;GO:0008284 positive regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BML5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BN68-1", "uniprot_id": [ { "id": "A0A287BN68_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BN68", "type": "external" } ], "mass": 164785.0, "length": 1464, "protein_name": "Glutamate receptor", "gene_name": "GRIN2A", "organism": "Pig", "refseq_name": "glutamate receptor ionotropic, NMDA 2A isoform X1", "refseq_ac": [ { "id": "XP_020942311", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942311", "type": "external" } ], "gene_names_uniprotkb": "GRIN2A", "gene_names_refseq": "GRIN2A", "protein_names_uniprotkb": "Glutamate receptor", "protein_names_refseq": "glutamate receptor ionotropic, NMDA 2A isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100736832); (R-SSC-438066); (R-SSC-8849932); (R-SSC-9609736)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0022849 glutamate-gated calcium ion channel activity;GO:0046872 metal ion binding;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential;GO:0004972 NMDA glutamate receptor activity;GO:0005261 monoatomic cation channel activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0017146 NMDA selective glutamate receptor complex;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0007611 learning or memory;GO:0045471 response to ethanol;GO:0060079 excitatory postsynaptic potential;GO:0035249 synaptic transmission, glutamatergic;GO:0035725 sodium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BN68-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BNA7-1", "uniprot_id": [ { "id": "A0A287BNA7_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BNA7", "type": "external" } ], "mass": 63998.0, "length": 563, "protein_name": "Neurofilament light polypeptide", "gene_name": "NEFL", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "NEFL", "gene_names_refseq": "", "protein_names_uniprotkb": "Neurofilament light polypeptide; Neurofilament triplet L protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100521224); (R-SSC-438066); (R-SSC-5673001)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0042802 identical protein binding;GO:0015631 tubulin binding;GO:0099184 structural constituent of postsynaptic intermediate filament cytoskeleton", "go_cellular_component": "GO:0030424 axon;GO:0031594 neuromuscular junction;GO:0005882 intermediate filament;GO:1904115 axon cytoplasm;GO:0005883 neurofilament", "go_biological_process": "GO:0008090 retrograde axonal transport;GO:0008089 anterograde axonal transport;GO:0090128 regulation of synapse maturation;GO:0019896 axonal transport of mitochondrion;GO:0033693 neurofilament bundle assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BNA7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BPE2-1", "uniprot_id": [ { "id": "A0A287BPE2_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BPE2", "type": "external" } ], "mass": 60294.0, "length": 554, "protein_name": "Macrophage colony-stimulating factor 1", "gene_name": "CSF1", "organism": "Pig", "refseq_name": "macrophage colony-stimulating factor 1 isoform 1 precursor", "refseq_ac": [ { "id": "NP_001422310", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422310", "type": "external" } ], "gene_names_uniprotkb": "CSF1", "gene_names_refseq": "CSF1; MCSFBETA", "protein_names_uniprotkb": "Macrophage colony-stimulating factor 1; CSF-1; MCSF", "protein_names_refseq": "MCSF alpha; colony stimulating factor 1 (macrophage); macrophage colony stimulating factor alpha; macrophage colony stimulating factor beta; macrophage colony-stimulating factor 1 isoform 1 precursor", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-381426); (R-SSC-449836); (R-SSC-8957275); (R-SSC-9856649)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "23260168;32543654", "class_list": "", "function": "Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; The feline CSF-1R was cloned and the responsiveness to CSF-1 and IL-34 from a range of species, was examined., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005157 macrophage colony-stimulating factor receptor binding;GO:0042803 protein homodimerization activity;GO:0005125 cytokine activity;GO:0008083 growth factor activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:1990682 CSF1-CSF1R complex;GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0003006 developmental process involved in reproduction;GO:0030316 osteoclast differentiation;GO:0032946 positive regulation of mononuclear cell proliferation;GO:0038145 macrophage colony-stimulating factor signaling pathway;GO:1902228 positive regulation of macrophage colony-stimulating factor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A287BPE2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BQF9-1", "uniprot_id": [ { "id": "A0A287BQF9_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BQF9", "type": "external" } ], "mass": 119601.0, "length": 1087, "protein_name": "Histone deacetylase", "gene_name": "HDAC4", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "HDAC4", "gene_names_refseq": "", "protein_names_uniprotkb": "Histone deacetylase; 3.5.1.98", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-350054); (R-SSC-4090294); (R-SSC-4551638); (R-SSC-8951936)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0019901 protein kinase binding;GO:0046872 metal ion binding;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0031594 neuromuscular junction;GO:0000118 histone deacetylase complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0014894 response to denervation involved in regulation of muscle adaptation;GO:0045820 negative regulation of glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BQF9-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BRJ4-1", "uniprot_id": [ { "id": "A0A287BRJ4_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BRJ4", "type": "external" } ], "mass": 33545.0, "length": 295, "protein_name": "Cyclin D1", "gene_name": "CCND1", "organism": "Pig", "refseq_name": "G1/S-specific cyclin-D1", "refseq_ac": [ { "id": "XP_020938345", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020938345", "type": "external" } ], "gene_names_uniprotkb": "CCND1", "gene_names_refseq": "CCND1", "protein_names_uniprotkb": "Cyclin D1", "protein_names_refseq": "G1/S-specific cyclin-D1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100738589); (R-SSC-187577); (R-SSC-3214858); (R-SSC-69231); (R-SSC-75815); (R-SSC-8849470); (R-SSC-8878166); (R-SSC-8934593); (R-SSC-8951936); (R-SSC-9754119); (R-SSC-9929491)", "pathway_count": 11, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004672 protein kinase activity;GO:0019901 protein kinase binding;GO:0003714 transcription corepressor activity;GO:0042826 histone deacetylase binding;GO:0070064 proline-rich region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005923 bicellular tight junction;GO:0031965 nuclear membrane", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0010971 positive regulation of G2/M transition of mitotic cell cycle;GO:0051301 cell division;GO:0000082 G1/S transition of mitotic cell cycle;GO:1900087 positive regulation of G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BRJ4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A287BRY9-1", "uniprot_id": [ { "id": "A0A287BRY9_PIG", "url": "https://www.uniprot.org/uniprot/A0A287BRY9", "type": "external" } ], "mass": 19827.0, "length": 185, "protein_name": "Midkine", "gene_name": "MDK", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "MDK", "gene_names_refseq": "", "protein_names_uniprotkb": "Midkine; MK", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-201556); (R-SSC-9851151)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Secreted protein that functions as cytokine and growth factor and mediates its signal through cell-surface proteoglycan and non-proteoglycan receptors. Regulates many processes like inflammatory response, cell proliferation, cell adhesion, cell growth, cell survival, tissue regeneration, cell differentiation and cell migration., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:1904399 heparan sulfate binding;GO:0008083 growth factor activity;GO:0035374 chondroitin sulfate binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:2000347 positive regulation of hepatocyte proliferation;GO:1905564 positive regulation of vascular endothelial cell proliferation;GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell;GO:1904036 negative regulation of epithelial cell apoptotic process;GO:0021681 cerebellar granular layer development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A287BRY9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A288CFV5-1", "uniprot_id": [ { "id": "A0A288CFV5_PIG", "url": "https://www.uniprot.org/uniprot/A0A288CFV5", "type": "external" } ], "mass": 81819.0, "length": 740, "protein_name": "Serotransferrin", "gene_name": "TF", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "TF", "gene_names_refseq": "", "protein_names_uniprotkb": "Serotransferrin; Beta-1 metal-binding globulin; Siderophilin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-114608); (R-SSC-381426); (R-SSC-8856825); (R-SSC-8856828); (R-SSC-8957275); (R-SSC-917937); (R-SSC-917977)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0019899 enzyme binding;GO:0044325 transmembrane transporter binding;GO:0008198 ferrous iron binding;GO:0034986 iron chaperone activity;GO:1990459 transferrin receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit;GO:0009986 cell surface", "go_biological_process": "GO:0030316 osteoclast differentiation;GO:0007166 cell surface receptor signaling pathway;GO:0019731 antibacterial humoral response;GO:0006879 intracellular iron ion homeostasis;GO:0071281 cellular response to iron ion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A288CFV5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A2C9F339-1", "uniprot_id": [ { "id": "A0A2C9F339_PIG", "url": "https://www.uniprot.org/uniprot/A0A2C9F339", "type": "external" } ], "mass": 38526.0, "length": 361, "protein_name": "POU domain protein", "gene_name": "POU5F1", "organism": "Pig", "refseq_name": "POU domain, class 5, transcription factor 1 isoform X1", "refseq_ac": [ { "id": "XP_020953528", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020953528", "type": "external" } ], "gene_names_uniprotkb": "POU5F1", "gene_names_refseq": "OCT3; OCT4; Oct-4; POU5F1", "protein_names_uniprotkb": "POU domain protein", "protein_names_refseq": "POU domain, class 5, transcription factor 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0031490 chromatin DNA binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0017053 transcription repressor complex;GO:0000785 chromatin", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0009786 regulation of asymmetric cell division;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A2C9F339-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A2C9F389-1", "uniprot_id": [ { "id": "A0A2C9F389_PIG", "url": "https://www.uniprot.org/uniprot/A0A2C9F389", "type": "external" } ], "mass": 122179.0, "length": 1163, "protein_name": "Large proline-rich protein BAG6", "gene_name": "BAG6", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "BAG6", "gene_names_refseq": "", "protein_names_uniprotkb": "Large proline-rich protein BAG6; BCL2-associated athanogene 6; HLA-B-associated transcript 3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Involved in DNA damage-induced apoptosis: following DNA damage, accumulates in the nucleus and forms a complex with p300/EP300, enhancing p300/EP300-mediated p53/TP53 acetylation leading to increase p53/TP53 transcriptional activity. When nuclear, may also act as a component of some chromatin regulator complex that regulates histone 3 'Lys-4' dimethylation (H3K4me2)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Released extracellularly via exosomes, it is a ligand of the natural killer/NK cells receptor NCR3 and stimulates NK cells cytotoxicity. It may thereby trigger NK cells cytotoxicity against neighboring tumor cells and immature myeloid dendritic cells (DC)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031593 polyubiquitin modification-dependent protein binding;GO:0031625 ubiquitin protein ligase binding;GO:0043022 ribosome binding;GO:1990381 ubiquitin-specific protease binding;GO:0070628 proteasome binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0016020 membrane;GO:0070062 extracellular exosome;GO:0071818 BAT3 complex;GO:0005576 extracellular region", "go_biological_process": "GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane;GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0001822 kidney development;GO:0030324 lung development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A2C9F389-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A2C9F3B4-1", "uniprot_id": [ { "id": "A0A2C9F3B4_PIG", "url": "https://www.uniprot.org/uniprot/A0A2C9F3B4", "type": "external" } ], "mass": 32740.0, "length": 301, "protein_name": "Uncoupling protein 2", "gene_name": "UCP2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "UCP2", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncoupling protein 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-167826)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0015297 antiporter activity;GO:0019003 GDP binding;GO:0015078 proton transmembrane transporter activity;GO:0015108 chloride transmembrane transporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0009409 response to cold;GO:0071333 cellular response to glucose stimulus;GO:0001666 response to hypoxia;GO:0051881 regulation of mitochondrial membrane potential;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A2C9F3B4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A2C9F3E9-1", "uniprot_id": [ { "id": "A0A2C9F3E9_PIG", "url": "https://www.uniprot.org/uniprot/A0A2C9F3E9", "type": "external" } ], "mass": 81737.0, "length": 744, "protein_name": "Junction plakoglobin", "gene_name": "JUP", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "JUP", "gene_names_refseq": "", "protein_names_uniprotkb": "Junction plakoglobin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-418990); (R-SSC-5218920); (R-SSC-6798695); (R-SSC-6805567); (R-SSC-6809371); (R-SSC-8980692); (R-SSC-9013026); (R-SSC-9013106); (R-SSC-9013148); (R-SSC-9013406); (R-SSC-9013407); (R-SSC-9762292); (R-SSC-9764561); (R-SSC-9766229); (R-SSC-9768727); (R-SSC-9958810); (R-SSC-9958825)", "pathway_count": 17, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0045296 cadherin binding;GO:0019903 protein phosphatase binding;GO:0045294 alpha-catenin binding;GO:0016922 nuclear receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005912 adherens junction;GO:0005882 intermediate filament", "go_biological_process": "GO:0042307 positive regulation of protein import into nucleus;GO:0016477 cell migration;GO:0042127 regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0072659 protein localization to plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A2C9F3E9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A2C9F3F0-1", "uniprot_id": [ { "id": "A0A2C9F3F0_PIG", "url": "https://www.uniprot.org/uniprot/A0A2C9F3F0", "type": "external" } ], "mass": 16172.0, "length": 155, "protein_name": "Superoxide dismutase [Cu-Zn]", "gene_name": "SOD1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SOD1", "gene_names_refseq": "", "protein_names_uniprotkb": "Superoxide dismutase [Cu-Zn]; 1.15.1.1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Destroys radicals which are normally produced within the cells and which are toxic to biological systems., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0051087 protein-folding chaperone binding;GO:0031267 small GTPase binding;GO:0005507 copper ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0005777 peroxisome", "go_biological_process": "GO:0008090 retrograde axonal transport;GO:0032930 positive regulation of superoxide anion generation;GO:0050728 negative regulation of inflammatory response;GO:0051881 regulation of mitochondrial membrane potential;GO:0060047 heart contraction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A2C9F3F0-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A2C9F3G7-1", "uniprot_id": [ { "id": "A0A2C9F3G7_PIG", "url": "https://www.uniprot.org/uniprot/A0A2C9F3G7", "type": "external" } ], "mass": 75007.0, "length": 663, "protein_name": "Polyunsaturated fatty acid lipoxygenase ALOX15", "gene_name": "ALOX15", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ALOX15", "gene_names_refseq": "", "protein_names_uniprotkb": "Polyunsaturated fatty acid lipoxygenase ALOX15; 1.13.11.12; 1.13.11.31; 1.13.11.33; 12/15-lipoxygenase; Arachidonate 12-lipoxygenase, leukocyte-type; Arachidonate 15-lipoxygenase; Arachidonate omega-6 lipoxygenase; Erythroid cell-specific 15-lipoxygenase; Hepoxilin A3 synthase Alox15; Linoleate 13S-lipoxygenase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005506 iron ion binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0004052 arachidonate 12(S)-lipoxygenase activity;GO:0016165 linoleate 13S-lipoxygenase activity;GO:0050473 arachidonate 15-lipoxygenase activity", "go_cellular_component": "GO:0005811 lipid droplet;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0034440 lipid oxidation;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0043651 linoleic acid metabolic process;GO:0071277 cellular response to calcium ion;GO:0010811 positive regulation of cell-substrate adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A2C9F3G7-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A480E801-1", "uniprot_id": [ { "id": "A0A480E801_PIG", "url": "https://www.uniprot.org/uniprot/A0A480E801", "type": "external" } ], "mass": 35522.0, "length": 314, "protein_name": "NAD-dependent protein lipoamidase sirtuin-4, mitochondrial", "gene_name": "SIRT4", "organism": "Pig", "refseq_name": "NAD-dependent protein lipoamidase sirtuin-4, mitochondrial", "refseq_ac": [ { "id": "NP_001107742", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107742", "type": "external" } ], "gene_names_uniprotkb": "SIRT4", "gene_names_refseq": "SIRT4", "protein_names_uniprotkb": "NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; 2.3.1.-; 2.3.1.286; 2.4.2.-; NAD-dependent ADP-ribosyltransferase sirtuin-4; NAD-dependent protein biotinylase sirtuin-4; NAD-dependent protein deacetylase sirtuin-4; Regulatory protein SIR2 homolog 4; SIR2-like protein 4", "protein_names_refseq": "NAD-dependent protein lipoamidase sirtuin-4, mitochondrial", "tax_id": 9823, "disease": "", "pathway": " (ssc:100125349); (R-SSC-204174); (R-SSC-2151201)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Acts as NAD-dependent protein lipoamidase, biotinylase, deacetylase and ADP-ribosyl transferase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitochondrial glutamine metabolism by mediating mono ADP-ribosylation of GLUD1: expressed in response to DNA damage and negatively regulates anaplerosis by inhibiting GLUD1, leading to block metabolism of glutamine into tricarboxylic acid cycle and promoting cell cycle arrest. In response to mTORC1 signal, SIRT4 expression is repressed, promoting anaplerosis and cell proliferation. Acts as a tumor suppressor. Also acts as a NAD-dependent protein deacetylase: mediates deacetylation of 'Lys-471' of MLYCD, inhibiting its activity, thereby acting as a regulator of lipid homeostasis. Does not seem to deacetylate PC. Controls fatty acid oxidation by inhibiting PPARA transcriptional activation. Impairs SIRT1-PPARA interaction probably through the regulation of NAD(+) levels. Down-regulates insulin secretion., [UniProtKB, HAMAP]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A5G2RB95", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0070403 NAD+ binding;GO:0004407 histone deacetylase activity;GO:0003950 NAD+ poly-ADP-ribosyltransferase activity;GO:0061690 lipoamidase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0046322 negative regulation of fatty acid oxidation;GO:0046889 positive regulation of lipid biosynthetic process;GO:0006974 DNA damage response;GO:0046676 negative regulation of insulin secretion;GO:0006541 glutamine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A480E801-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A480HLM0-1", "uniprot_id": [ { "id": "A0A480HLM0_PIG", "url": "https://www.uniprot.org/uniprot/A0A480HLM0", "type": "external" } ], "mass": 34057.0, "length": 307, "protein_name": "Cyclin-dependent kinase 5 activator", "gene_name": "CDK5R1", "organism": "Pig", "refseq_name": "cyclin-dependent kinase 5 activator 1 isoform X1", "refseq_ac": [ { "id": "XP_020921681", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020921681", "type": "external" } ], "gene_names_uniprotkb": "CDK5R1", "gene_names_refseq": "CDK5R1", "protein_names_uniprotkb": "Cyclin-dependent kinase 5 activator", "protein_names_refseq": "cyclin-dependent kinase 5 activator 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-399956); (R-SSC-6804756)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-BMAL1 heterodimer in association with altered stability and subcellular distribution., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F2Z529", "ec_number_list": [], "go_molecular_function": "GO:0002020 protease binding;GO:0019901 protein kinase binding;GO:0051015 actin filament binding;GO:0016301 kinase activity;GO:0035255 ionotropic glutamate receptor binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030426 growth cone;GO:0043204 perikaryon", "go_biological_process": "GO:0021799 cerebral cortex radially oriented cell migration;GO:0032956 regulation of actin cytoskeleton organization;GO:0048013 ephrin receptor signaling pathway;GO:0001764 neuron migration;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A480HLM0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A480IV55-1", "uniprot_id": [ { "id": "A0A480IV55_PIG", "url": "https://www.uniprot.org/uniprot/A0A480IV55", "type": "external" } ], "mass": 127325.0, "length": 1167, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "HIPK2", "organism": "Pig", "refseq_name": "homeodomain-interacting protein kinase 2 isoform X5", "refseq_ac": [ { "id": "XP_020934213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020934213", "type": "external" } ], "gene_names_uniprotkb": "HIPK2", "gene_names_refseq": "HIPK2", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "homeodomain-interacting protein kinase 2 isoform X5", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-3899300); (R-SSC-6804756); (R-SSC-8939243); (R-SSC-9022692)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "I3LHT2", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0003713 transcription coactivator activity;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016605 PML body;GO:0090575 RNA polymerase II transcription regulator complex;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0060059 embryonic retina morphogenesis in camera-type eye;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0046330 positive regulation of JNK cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A480IV55-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A480K9W0-1", "uniprot_id": [ { "id": "A0A480K9W0_PIG", "url": "https://www.uniprot.org/uniprot/A0A480K9W0", "type": "external" } ], "mass": 96332.0, "length": 841, "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "organism": "Pig", "refseq_name": "toll-like receptor 4 isoform 1 precursor", "refseq_ac": [ { "id": "NP_001106510", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106510", "type": "external" } ], "gene_names_uniprotkb": "TLR4", "gene_names_refseq": "TLR4", "protein_names_uniprotkb": "Toll-like receptor 4", "protein_names_refseq": "toll-like receptor 4 isoform 1 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:399541); (R-SSC-140534); (R-SSC-166016); (R-SSC-166166); (R-SSC-2562578); (R-SSC-5686938); (R-SSC-936964); (R-SSC-937041); (R-SSC-937072); (R-SSC-9707616); (R-SSC-975163); (R-SSC-9824878)", "pathway_count": 12, "publication_count": 9, "publication_id_list": "15375763;15869793;16139355;27487503;28744451;29229731;29510469;32543654;34439812", "class_list": "", "function": "A high level of conservation of TLR4 gene size and sequence, especially for the two last exons and particularly in the sequence corresponding to the LRRs and TIR domain, is observed between species, [RefSeq, PubMed]; Actinobacillus pleuropneumoniae induces alveolar Macrophages to produce proinflammatory cytokines via upregulation of TLR4 and NF-kappaB. Publication Status: Online-Only, [RefSeq, PubMed]; CDNA containing the porcine Toll-like receptor 4 (TLR4) coding sequence has been cloned by RT-PCR from alveolar macrophages mRNA, [RefSeq, PubMed]; Data suggest that expression of TLR4 in intestinal mucosa can be regulated by dietary factors; here, flaxseed oil down-regulates expression of TLR4 in piglet model of necrotizing enterocolitis., [RefSeq, PubMed]; High Mobility Group Box 1 in Pig Amniotic Membrane Experimentally Infected with E. coli O55. Publication Status: Online-Only, [RefSeq, PubMed]; Similarity in TLR4 staining in macrophages, epithelium and vascular endothelium among dog, pig and cattle, [RefSeq, PubMed]; The TWEAK-independent Fn14 activation augments TLR4-mediated inflammatory responses in the intestine of piglets. Publication Status: Online-Only, [RefSeq, PubMed]; These results further confirm the involvement of the TLR4 signaling pathway in resistance to E. coli F18 in Meishan weaned piglets., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0005102 signaling receptor binding;GO:0042802 identical protein binding;GO:0046982 protein heterodimerization activity;GO:0001530 lipopolysaccharide binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0032727 positive regulation of interferon-alpha production;GO:0043032 positive regulation of macrophage activation;GO:0032700 negative regulation of interleukin-17 production;GO:0002246 wound healing involved in inflammatory response;GO:1904466 positive regulation of matrix metallopeptidase secretion", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "A0A480K9W0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A480KMF2-1", "uniprot_id": [ { "id": "A0A480KMF2_PIG", "url": "https://www.uniprot.org/uniprot/A0A480KMF2", "type": "external" } ], "mass": 36808.0, "length": 328, "protein_name": "Laforin", "gene_name": "EPM2A; FBXO30", "organism": "Pig", "refseq_name": "laforin isoform X1", "refseq_ac": [ { "id": "XP_001927667", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927667", "type": "external" } ], "gene_names_uniprotkb": "EPM2A; FBXO30; EPM2A", "gene_names_refseq": "EPM2A", "protein_names_uniprotkb": "Laforin; 3.1.3.16; 3.1.3.48; Glucan phosphatase; Lafora PTPase", "protein_names_refseq": "laforin isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100153341)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1S734", "ec_number_list": [], "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0004722 protein serine/threonine phosphatase activity;GO:0004373 alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity;GO:2001070 starch binding;GO:0019203 carbohydrate phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0006914 autophagy;GO:0005978 glycogen biosynthetic process;GO:0046835 carbohydrate phosphorylation;GO:0009892 negative regulation of metabolic process;GO:0006796 phosphate-containing compound metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A480KMF2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A480KVF0-1", "uniprot_id": [ { "id": "A0A480KVF0_PIG", "url": "https://www.uniprot.org/uniprot/A0A480KVF0", "type": "external" } ], "mass": 53498.0, "length": 478, "protein_name": "Lipoprotein lipase", "gene_name": "LPL", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "LPL", "gene_names_refseq": "", "protein_names_uniprotkb": "Lipoprotein lipase; 3.1.1.34; LPL", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-8963889); (R-SSC-8963901); (R-SSC-975634)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, 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high-density lipoprotein particle remodeling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A480KVF0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A480LD13-1", "uniprot_id": [ { "id": "A0A480LD13_PIG", "url": "https://www.uniprot.org/uniprot/A0A480LD13", "type": "external" } ], "mass": 66604.0, "length": 588, "protein_name": "Cryptochrome-1", "gene_name": "CRY1", "organism": "Pig", "refseq_name": "cryptochrome-1", "refseq_ac": [ { "id": "XP_003126127", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003126127", "type": "external" } ], "gene_names_uniprotkb": "CRY1", "gene_names_refseq": "CRY1", "protein_names_uniprotkb": "Cryptochrome-1", "protein_names_refseq": "cryptochrome-1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100520380)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", 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"glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A286ZMF9;A0A4X1SJC5", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0019901 protein kinase binding;GO:0071949 FAD binding;GO:0042826 histone deacetylase binding;GO:0070888 E-box binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:2000001 regulation of DNA damage checkpoint;GO:2000850 negative regulation of glucocorticoid secretion;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045744 negative regulation of G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A480LD13-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A480LMF4-1", "uniprot_id": [ { "id": "A0A480LMF4_PIG", "url": "https://www.uniprot.org/uniprot/A0A480LMF4", "type": "external" } ], "mass": 68012.0, "length": 593, "protein_name": "Tyrosine-protein phosphatase non-receptor type", "gene_name": "PTPN11", "organism": "Pig", "refseq_name": "tyrosine-protein phosphatase non-receptor type 11 isoform X3", "refseq_ac": [ { "id": "XP_013845818", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013845818", "type": "external" } ], "gene_names_uniprotkb": "PTPN11", "gene_names_refseq": "PTPN11", "protein_names_uniprotkb": "Tyrosine-protein phosphatase non-receptor type; 3.1.3.48", "protein_names_refseq": "tyrosine-protein phosphatase non-receptor type 11 isoform X3", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1059683); (R-SSC-109704); (R-SSC-112411); (R-SSC-114604); (R-SSC-1257604); (R-SSC-1295596); (R-SSC-1433557); (R-SSC-180292); (R-SSC-186763); (R-SSC-210990); (R-SSC-210993); (R-SSC-389513); (R-SSC-389948); (R-SSC-432142); (R-SSC-512988); (R-SSC-5654689); (R-SSC-5654693); (R-SSC-5654695); (R-SSC-5654700); (R-SSC-5654706); (R-SSC-5654710); (R-SSC-5654712); (R-SSC-5654720); (R-SSC-5654726); (R-SSC-5654727); (R-SSC-5654732); (R-SSC-5654733); (R-SSC-6811558); (R-SSC-8853659); (R-SSC-8854691); (R-SSC-8865999); (R-SSC-8934593); (R-SSC-912694); (R-SSC-936964); (R-SSC-9674555)", "pathway_count": 35, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, 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"go_biological_process": "GO:0036302 atrioventricular canal development;GO:0048806 genitalia development;GO:0038127 ERBB signaling pathway;GO:0048013 ephrin receptor signaling pathway;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A480LMF4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1UD21-1", "uniprot_id": [ { "id": "A0A4X1UD21_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1UD21", "type": "external" } ], "mass": 76772.0, "length": 680, "protein_name": "Tumor protein 63 (p63)", "gene_name": "TP63", "organism": "Pig", "refseq_name": "tumor protein 63 isoform X1", "refseq_ac": [ { "id": "XP_020925700", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020925700", "type": "external" } ], "gene_names_uniprotkb": "TP63", "gene_names_refseq": "TP63", "protein_names_uniprotkb": "Tumor protein 63 (p63)", "protein_names_refseq": "tumor protein 63 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-6804759)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Multifunctional transcription factor that induces cell cycle arrest, DNA repair or apoptosis upon binding to its target DNA sequence. Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Negatively regulates cell division by controlling expression of a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. 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2.7.11.1", "protein_names_refseq": "ribosomal protein S6 kinase beta-1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100127158); (R-SSC-166208)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A481C7T7", "ec_number_list": [], "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005741 mitochondrial outer membrane;GO:0043005 neuron projection", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0031670 cellular response to nutrient;GO:0032869 cellular response to insulin stimulus;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A4X1STL0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1SY68-1", "uniprot_id": [ { "id": "A0A4X1SY68_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1SY68", "type": "external" } ], "mass": 69851.0, "length": 603, "protein_name": "Myotubularin", "gene_name": "MTM1", "organism": "Pig", "refseq_name": "myotubularin isoform X4", "refseq_ac": [ { "id": "XP_003135511", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003135511", "type": "external" } ], "gene_names_uniprotkb": "MTM1", "gene_names_refseq": "MTM1", "protein_names_uniprotkb": "Myotubularin; 3.1.3.95; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase; Phosphatidylinositol-3-phosphate phosphatase", "protein_names_refseq": "myotubularin isoform X4", "tax_id": 9823, "disease": "", "pathway": " (ssc:100516892); (R-SSC-1660499); (R-SSC-1660516); (R-SSC-1660517)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis. 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"0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1TRG4-1", "uniprot_id": [ { "id": "A0A4X1TRG4_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1TRG4", "type": "external" } ], "mass": 85376.0, "length": 749, "protein_name": "Phospholipase A2", "gene_name": "PLA2G4A", "organism": "Pig", "refseq_name": "cytosolic phospholipase A2", "refseq_ac": [ { "id": "XP_003130441", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003130441", "type": "external" } ], "gene_names_uniprotkb": "PLA2G4A", "gene_names_refseq": "PLA2G4A", "protein_names_uniprotkb": "Phospholipase A2; 3.1.1.4", "protein_names_refseq": "cytosolic phospholipase A2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100520687); (R-SSC-111995); (R-SSC-1482788); (R-SSC-1482798); (R-SSC-1482801); (R-SSC-1482839); (R-SSC-1482922); (R-SSC-1482925); (R-SSC-1483115); (R-SSC-1483166); (R-SSC-2142753); (R-SSC-418592); (R-SSC-432142); (R-SSC-6811436)", 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"record_id": "A0A4X1TRG4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1TPR3-1", "uniprot_id": [ { "id": "A0A4X1TPR3_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1TPR3", "type": "external" } ], "mass": 53647.0, "length": 471, "protein_name": "Sestrin 2", "gene_name": "SESN2", "organism": "Pig", "refseq_name": "sestrin-2", "refseq_ac": [ { "id": "XP_003356286", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003356286", "type": "external" } ], "gene_names_uniprotkb": "SESN2", "gene_names_refseq": "SESN2", "protein_names_uniprotkb": "Sestrin 2", "protein_names_refseq": "sestrin-2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100620966); (R-SSC-5628897); (R-SSC-9639288); (R-SSC-9755511)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 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"kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1TUM3-1", "uniprot_id": [ { "id": "A0A4X1TUM3_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1TUM3", "type": "external" } ], "mass": 52583.0, "length": 456, "protein_name": "Glycine receptor alpha 1", "gene_name": "GLRA1", "organism": "Pig", "refseq_name": "glycine receptor subunit alpha-1 isoform X1", "refseq_ac": [ { "id": "XP_013840362", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013840362", "type": "external" } ], "gene_names_uniprotkb": "GLRA1", "gene_names_refseq": "GLRA1", "protein_names_uniprotkb": "Glycine receptor alpha 1", "protein_names_refseq": "glycine receptor subunit alpha-1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100513384); (R-SSC-112314)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "32543654;34555840", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, 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"ec_number_list": [], "go_molecular_function": "GO:0016934 extracellularly glycine-gated chloride channel activity;GO:0030977 taurine binding;GO:0004888 transmembrane signaling receptor activity;GO:0008270 zinc ion binding;GO:0016594 glycine binding", "go_cellular_component": "GO:0030425 dendrite;GO:0043204 perikaryon;GO:0045211 postsynaptic membrane;GO:0009897 external side of plasma membrane;GO:0034707 chloride channel complex", "go_biological_process": "GO:2000344 positive regulation of acrosome reaction;GO:0051970 negative regulation of transmission of nerve impulse;GO:0006936 muscle contraction;GO:0007218 neuropeptide signaling pathway;GO:0071361 cellular response to ethanol", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A4X1TUM3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.1000000000000.100.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1U640-1", "uniprot_id": [ { "id": "A0A4X1U640_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1U640", "type": "external" } ], "mass": 28820.0, "length": 254, "protein_name": "small monomeric GTPase", "gene_name": "RAB3A", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "RAB3A", "gene_names_refseq": "", "protein_names_uniprotkb": "small monomeric GTPase; 3.6.5.2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-181429); (R-SSC-181430); (R-SSC-210500); (R-SSC-212676); (R-SSC-264642); (R-SSC-6798695); (R-SSC-8876198); (R-SSC-888590)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287B419;A0A5S6GDB5", "ec_number_list": [], "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0030674 protein-macromolecule adaptor activity;GO:0030742 GTP-dependent protein binding;GO:0031489 myosin V binding", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0030424 axon;GO:0043195 terminal bouton;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0001778 plasma membrane repair;GO:0097091 synaptic vesicle clustering;GO:0048172 regulation of short-term neuronal synaptic plasticity;GO:0061670 evoked neurotransmitter secretion;GO:1903307 positive regulation of regulated secretory pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A4X1U640-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1U8B7-1", "uniprot_id": [ { "id": "A0A4X1U8B7_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1U8B7", "type": "external" } ], "mass": 68688.0, "length": 610, "protein_name": "72 kDa type IV collagenase", "gene_name": "MMP2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "MMP2", "gene_names_refseq": "", "protein_names_uniprotkb": "72 kDa type IV collagenase; 3.4.24.24; 72 kDa gelatinase; Matrix metalloproteinase-2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1442490); (R-SSC-1474228); (R-SSC-1592389); (R-SSC-3928665); (R-SSC-9009391)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A5G2R860", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0031012 extracellular matrix;GO:0030017 sarcomere", "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization;GO:0001666 response to hypoxia;GO:1904645 response to amyloid-beta;GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A4X1U8B7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001001.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1UEL7-1", "uniprot_id": [ { "id": "A0A4X1UEL7_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1UEL7", "type": "external" } ], "mass": 45835.0, "length": 406, "protein_name": "Lysosomal phospholipase A and acyltransferase", "gene_name": "PLA2G15", "organism": "Pig", "refseq_name": "group XV phospholipase A2 isoform X1", "refseq_ac": [ { "id": "XP_020949819", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020949819", "type": "external" } ], "gene_names_uniprotkb": "PLA2G15", "gene_names_refseq": "PLA2G15", "protein_names_uniprotkb": "Lysosomal phospholipase A and acyltransferase; 1-O-acylceramide synthase; 3.1.1.32; 3.1.1.4; 3.1.1.5; LCAT-like lysophospholipase; Lysophospholipase 3; Lysosomal phospholipase A2; Phospholipase A2 group XV", "protein_names_refseq": "group XV phospholipase A2 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:110260948); (R-SSC-1483115)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8W4FJU8", "ec_number_list": [], "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004622 phosphatidylcholine lysophospholipase activity;GO:0004623 phospholipase A2 activity;GO:0008970 phospholipase A1 activity;GO:0016411 acylglycerol O-acyltransferase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0005764 lysosome", "go_biological_process": "GO:0046338 phosphatidylethanolamine catabolic process;GO:0034638 phosphatidylcholine catabolic process;GO:0006631 fatty acid metabolic process;GO:0006672 ceramide metabolic process;GO:0046470 phosphatidylcholine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A4X1UEL7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1UM84-1", "uniprot_id": [ { "id": "PCKGC_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1UM84", "type": "external" } ], "mass": 68884.0, "length": 622, "protein_name": "Phosphoenolpyruvate carboxykinase, cytosolic [GTP]", "gene_name": "PCK1", "organism": "Pig", "refseq_name": "phosphoenolpyruvate carboxykinase, cytosolic [GTP]", "refseq_ac": [ { "id": "NP_001116630", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116630", "type": "external" } ], "gene_names_uniprotkb": "PCK1; PEPCK1", "gene_names_refseq": "PCK1; PEPCK-C; PEPCK1", "protein_names_uniprotkb": "Phosphoenolpyruvate carboxykinase, cytosolic [GTP]; 2.7.11.-; 4.1.1.32; PEPCK-C; Serine-protein kinase PCK1", "protein_names_refseq": "phosphoenolpyruvate carboxykinase 1 (soluble); phosphoenolpyruvate carboxykinase, cytosolic [GTP]; phosphoenolpyruvate carboxykinase, cytosolic; serine-protein kinase PCK1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144531)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "21795643;26792594;28644880;32543654", "class_list": "", "function": "Cytosolic phosphoenolpyruvate carboxykinase that catalyzes the reversible decarboxylation and phosphorylation of oxaloacetate (OAA) and acts as the rate-limiting enzyme in gluconeogenesis (PubMed:26792594). Regulates cataplerosis and anaplerosis, the processes that control the levels of metabolic intermediates in the citric acid cycle (By similarity). At low glucose levels, it catalyzes the cataplerotic conversion of oxaloacetate to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity). At high glucose levels, it catalyzes the anaplerotic conversion of phosphoenolpyruvate to oxaloacetate (By similarity). Acts as a regulator of formation and maintenance of memory CD8(+) T-cells: up-regulated in these cells, where it generates phosphoenolpyruvate, via gluconeogenesis (By similarity). The resultant phosphoenolpyruvate flows to glycogen and pentose phosphate pathway, which is essential for memory CD8(+) T-cells homeostasis (By similarity). In addition to the phosphoenolpyruvate carboxykinase activity, also acts as a protein kinase when phosphorylated at Ser-90: phosphorylation at Ser-90 by AKT1 reduces the binding affinity to oxaloacetate and promotes an atypical serine protein kinase activity using GTP as donor (By similarity). The protein kinase activity regulates lipogenesis: upon phosphorylation at Ser-90, translocates to the endoplasmic reticulum and catalyzes phosphorylation of INSIG proteins (INSIG1 and INSIG2), thereby disrupting the interaction between INSIG proteins and SCAP and promoting nuclear translocation of SREBP proteins (SREBF1/SREBP1 or SREBF2/SREBP2) and subsequent transcription of downstream lipogenesis-related genes (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed]; Study investigated the molecular basis of such effects focusing on a commonly studied polymorphism in pig Pgc1alpha, which changes a cysteine at position 430 (WT) of the protein to a serine (C430S); found that differential O-GlcNAcylation of Pgc1alpha regulates PCK1 activity and this molecular mechanism could explain at least in part the epistatic interaction between both genes. Erratum:[PLoS One. 2017 Aug 15;12(8):e0183566. doi: 10.1371/journal.pone.0183566. PMID: 28809945] Publication Status: Online-Only, [RefSeq, PubMed]; The renal proximal tubule, may require the remodeling of AUF1 binding to the elements that mediate the rapid turnover of PEPCK mRNA, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A5GFS4;K7GND0", "ec_number_list": [], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005525 GTP binding;GO:0030145 manganese ion binding;GO:0031406 carboxylic acid binding;GO:0004613 phosphoenolpyruvate carboxykinase (GTP) activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005829 cytosol", "go_biological_process": "GO:0032869 cellular response to insulin stimulus;GO:0071333 cellular response to glucose stimulus;GO:0046889 positive regulation of lipid biosynthetic process;GO:0006094 gluconeogenesis;GO:0006107 oxaloacetate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A4X1UM84-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1URL1-1", "uniprot_id": [ { "id": "A0A4X1URL1_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1URL1", "type": "external" } ], "mass": 74311.0, "length": 685, "protein_name": "Delta-like protein", "gene_name": "DLL4", "organism": "Pig", "refseq_name": "delta-like protein 4 precursor", "refseq_ac": [ { "id": "NP_001231347", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231347", "type": "external" } ], "gene_names_uniprotkb": "DLL4", "gene_names_refseq": "DLL4", "protein_names_uniprotkb": "Delta-like protein", "protein_names_refseq": "delta-like protein 4 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100152163)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate., [UniProtKB, UniProtKB]; Putative Notch ligand involved in the mediation of Notch signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287BFQ3", "ec_number_list": [], "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005112 Notch binding;GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0046331 lateral inhibition;GO:0061074 regulation of neural retina development;GO:0072554 blood vessel lumenization;GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis;GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A4X1URL1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1UUU5-1", "uniprot_id": [ { "id": "A0A4X1UUU5_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1UUU5", "type": "external" } ], "mass": 100331.0, "length": 870, "protein_name": "Extracellular sulfatase", "gene_name": "SULF1", "organism": "Pig", "refseq_name": "extracellular sulfatase Sulf-1 isoform X4", "refseq_ac": [ { "id": "XP_020944925", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020944925", "type": "external" } ], "gene_names_uniprotkb": "SULF1", "gene_names_refseq": "SULF1", "protein_names_uniprotkb": "Extracellular sulfatase; 3.1.6.-", "protein_names_refseq": "extracellular sulfatase Sulf-1 isoform X4", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287ACQ9", "ec_number_list": [], "go_molecular_function": "GO:0008449 N-acetylglucosamine-6-sulfatase activity;GO:0005509 calcium ion binding;GO:0004065 arylsulfatase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0045121 membrane raft", "go_biological_process": "GO:0060384 innervation;GO:0014846 esophagus smooth muscle contraction;GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway;GO:0010575 positive regulation of vascular endothelial growth factor production;GO:0030336 negative regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A4X1UUU5-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1UV69-1", "uniprot_id": [ { "id": "A0A4X1UV69_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1UV69", "type": "external" } ], "mass": 35398.0, "length": 318, "protein_name": "DNA repair nuclease/redox regulator APEX1", "gene_name": "APEX1", "organism": "Pig", "refseq_name": "DNA-(apurinic or apyrimidinic site) lyase isoform X1", "refseq_ac": [ { "id": "XP_020953697", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020953697", "type": "external" } ], "gene_names_uniprotkb": "APEX1", "gene_names_refseq": "APEX1", "protein_names_uniprotkb": "DNA repair nuclease/redox regulator APEX1; 3.1.11.2; 3.1.21.-; APEN; APEX nuclease; Apurinic-apyrimidinic endonuclease 1; REF-1; Redox factor-1", "protein_names_refseq": "DNA-(apurinic or apyrimidinic site) lyase isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-110357); (R-SSC-110362); (R-SSC-110373); (R-SSC-5651801); (R-SSC-73930); (R-SSC-73933)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287BTC2", "ec_number_list": [], "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0046872 metal ion binding;GO:0016491 oxidoreductase activity;GO:0003691 double-stranded telomeric DNA binding;GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005739 mitochondrion;GO:0016607 nuclear speck;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0044029 positive regulation of gene expression via chromosomal CpG island demethylation;GO:0006310 DNA recombination;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006284 base-excision repair;GO:0043488 regulation of mRNA stability", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A4X1UV69-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1UYQ0-1", "uniprot_id": [ { "id": "A0A4X1UYQ0_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1UYQ0", "type": "external" } ], "mass": 33796.0, "length": 303, "protein_name": "Crk-like protein", "gene_name": "CRKL", "organism": "Pig", "refseq_name": "crk-like protein", "refseq_ac": [ { "id": "XP_003133042", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003133042", "type": "external" } ], "gene_names_uniprotkb": "CRKL", "gene_names_refseq": "CRKL", "protein_names_uniprotkb": "Crk-like protein", "protein_names_refseq": "crk-like protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:100525363); (R-SSC-170968); (R-SSC-186763); (R-SSC-8875555); (R-SSC-8875656); (R-SSC-9027284); (R-SSC-912631)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "May mediate the transduction of intracellular signals., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "F1RKX9", "ec_number_list": [], "go_molecular_function": "GO:0001784 phosphotyrosine residue binding;GO:0042802 identical protein binding;GO:0030971 receptor tyrosine kinase binding;GO:0035591 signaling adaptor activity;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0098890 extrinsic component of postsynaptic membrane;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0031594 neuromuscular junction", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0010629 negative regulation of gene expression;GO:0016477 cell migration;GO:0035556 intracellular signal transduction;GO:0070374 positive regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A4X1UYQ0-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1UZH9-1", "uniprot_id": [ { "id": "A0A4X1UZH9_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1UZH9", "type": "external" } ], "mass": 67542.0, "length": 597, "protein_name": "Tyrosine-protein phosphatase non-receptor type", "gene_name": "PTPN6", "organism": "Pig", "refseq_name": "tyrosine-protein phosphatase non-receptor type 6 isoform X1", "refseq_ac": [ { "id": "XP_005652650", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005652650", "type": "external" } ], "gene_names_uniprotkb": "PTPN6", "gene_names_refseq": "PTPN6", "protein_names_uniprotkb": "Tyrosine-protein phosphatase non-receptor type; 3.1.3.48", "protein_names_refseq": "tyrosine-protein phosphatase non-receptor type 6 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100171389); (R-SSC-114604); (R-SSC-1433559); (R-SSC-201556); (R-SSC-210990); (R-SSC-389948); (R-SSC-432142); (R-SSC-512988); (R-SSC-5690714); (R-SSC-6798695); (R-SSC-877300); (R-SSC-912526); (R-SSC-912694); (R-SSC-983695)", "pathway_count": 14, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A480TLF2", "ec_number_list": [], "go_molecular_function": "GO:0001784 phosphotyrosine residue binding;GO:0017124 SH3 domain binding;GO:0019901 protein kinase binding;GO:0050839 cell adhesion molecule binding;GO:0042169 SH2 domain binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005911 cell-cell junction;GO:0042105 alpha-beta T cell receptor complex", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0008284 positive regulation of cell population proliferation;GO:0030154 cell differentiation;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0032715 negative regulation of interleukin-6 production", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A4X1UZH9-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1V142-1", "uniprot_id": [ { "id": "A0A4X1V142_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1V142", "type": "external" } ], "mass": 34635.0, "length": 315, "protein_name": "Protein sprouty homolog 2", "gene_name": "SPRY2", "organism": "Pig", "refseq_name": "protein sprouty homolog 2", "refseq_ac": [ { "id": "XP_001927132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001927132", "type": "external" } ], "gene_names_uniprotkb": "SPRY2", "gene_names_refseq": "SPRY2", "protein_names_uniprotkb": "Protein sprouty homolog 2", "protein_names_refseq": "protein sprouty homolog 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100157266); (R-SSC-1295596); (R-SSC-182971)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "F1RP67", "ec_number_list": [], "go_molecular_function": "GO:0019901 protein kinase binding;GO:0004860 protein kinase inhibitor activity;GO:0043539 protein serine/threonine kinase activator activity;GO:0030291 protein serine/threonine kinase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0015629 actin cytoskeleton;GO:0015630 microtubule cytoskeleton", "go_biological_process": "GO:0046580 negative regulation of Ras protein signal transduction;GO:0010628 positive regulation of gene expression;GO:0030335 positive regulation of cell migration;GO:0043066 negative regulation of apoptotic process;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A4X1V142-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1VDU3-1", "uniprot_id": [ { "id": "A0A4X1VDU3_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1VDU3", "type": "external" } ], "mass": 32429.0, "length": 275, "protein_name": "Autophagy protein 5", "gene_name": "ATG5", "organism": "Pig", "refseq_name": "autophagy protein 5", "refseq_ac": [ { "id": "NP_001032229", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032229", "type": "external" } ], "gene_names_uniprotkb": "ATG5", "gene_names_refseq": "ATG5", "protein_names_uniprotkb": "Autophagy protein 5", "protein_names_refseq": "ATG5 autophagy related 5 homolog; autophagy protein 5; autophagy related 5-like protein", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1632852); (R-SSC-5205685); (R-SSC-8934903)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "23056260;32543654", "class_list": "", "function": "Data indicate that the expression of MAP1LC3A, B and autophagy-associated genes (ATG5, mTOR, Beclin-1) was increased in normal pigs, while decreased in miniature pigs., [RefSeq, PubMed]; Involved in autophagic vesicle formation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A480XFP2", "ec_number_list": [], "go_molecular_function": "GO:0019776 Atg8-family ligase activity", "go_cellular_component": "GO:0034045 phagophore assembly site membrane;GO:0098978 glutamatergic synapse;GO:0030424 axon;GO:0098794 postsynapse;GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site", "go_biological_process": "GO:0016236 macroautophagy;GO:0007033 vacuole organization;GO:1904973 positive regulation of viral translation;GO:0000045 autophagosome assembly;GO:0043687 post-translational protein modification", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A4X1VDU3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A4X1VSJ0-1", "uniprot_id": [ { "id": "A0A4X1VSJ0_PIG", "url": "https://www.uniprot.org/uniprot/A0A4X1VSJ0", "type": "external" } ], "mass": 21956.0, "length": 196, "protein_name": "Bcl-2-like protein 11", "gene_name": "BCL2L11", "organism": "Pig", "refseq_name": "bcl-2-like protein 11 isoform X6", "refseq_ac": [ { "id": "XP_020941489", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020941489", "type": "external" } ], "gene_names_uniprotkb": "BCL2L11", "gene_names_refseq": "BCL2L11; 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Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; Jumonji domain-containing protein 6; Lysyl-hydroxylase JMJD6; Peptide-lysine 5-dioxygenase JMJD6; Phosphatidylserine receptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-3214842); (R-SSC-9629569)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0033746 histone H3R2 demethylase activity;GO:0033749 histone H4R3 demethylase activity;GO:0070815 peptidyl-lysine 5-dioxygenase activity;GO:0005506 iron ion binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051260 protein homooligomerization;GO:0006909 phagocytosis;GO:0002040 sprouting angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QPW8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A5G2QSP5-1", "uniprot_id": [ { "id": "A0A5G2QSP5_PIG", "url": "https://www.uniprot.org/uniprot/A0A5G2QSP5", "type": "external" } ], "mass": 109406.0, "length": 992, "protein_name": "tRNA (cytosine(34)-C(5))-methyltransferase", "gene_name": "NSUN2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "NSUN2", "gene_names_refseq": "", "protein_names_uniprotkb": "tRNA (cytosine(34)-C(5))-methyltransferase; 2.1.1.203; NOL1/NOP2/Sun domain family member 2; mRNA cytosine C(5)-methyltransferase; tRNA cytosine C(5)-methyltransferase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0016428 tRNA (cytidine-5-)-methyltransferase activity;GO:0000049 tRNA binding;GO:0062152 mRNA (cytidine-5-)-methyltransferase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0030488 tRNA methylation;GO:0033313 meiotic cell cycle checkpoint signaling;GO:0006397 mRNA processing;GO:0007286 spermatid development;GO:0010793 regulation of mRNA export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QSP5-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A5G2QS80-1", "uniprot_id": [ { "id": "A0A5G2QS80_PIG", "url": "https://www.uniprot.org/uniprot/A0A5G2QS80", "type": "external" } ], "mass": 41748.0, "length": 382, "protein_name": "CCN family member 1", "gene_name": "CCN1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CCN1", "gene_names_refseq": "", "protein_names_uniprotkb": "CCN family member 1; Cellular communication network factor 1; Cysteine-rich angiogenic inducer 61; Protein CYR61", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100153791); (R-SSC-381426); (R-SSC-8957275)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005178 integrin binding;GO:0008201 heparin binding;GO:0019838 growth factor binding;GO:0050840 extracellular matrix binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0007155 cell adhesion;GO:0007165 signal transduction;GO:0007229 integrin-mediated signaling pathway;GO:0030335 positive regulation of cell migration;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QS80-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "Q767M4-1", "uniprot_id": [ { "id": "Q767M4_PIG", "url": "https://www.uniprot.org/uniprot/Q767M4", "type": "external" } ], "mass": 101396.0, "length": 917, "protein_name": "Tyrosine-protein kinase receptor", "gene_name": "DDR1", "organism": "Pig", "refseq_name": "epithelial discoidin domain-containing receptor 1 precursor", "refseq_ac": [ { "id": "NP_001116577", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116577", "type": "external" } ], "gene_names_uniprotkb": "DDR1", "gene_names_refseq": "DDR1; DDR", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor; 2.7.10.1", "protein_names_refseq": "discoidin domain receptor family, member 1; epithelial discoidin domain-containing receptor 1 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144462)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A287A959;A0A4X1VJ19;A0A5G2QLR3;F1RU70;K7GMN3", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007565 female pregnancy;GO:0007595 lactation;GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q767M4-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZNW9-1", "uniprot_id": [ { "id": "A0A286ZNW9_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZNW9", "type": "external" } ], "mass": 95200.0, "length": 849, "protein_name": "DIS3-like exonuclease 2", "gene_name": "DIS3L2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "DIS3L2", "gene_names_refseq": "", "protein_names_uniprotkb": "DIS3-like exonuclease 2; 3.1.13.-", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0000175 3'-5'-RNA exonuclease activity;GO:0008266 poly(U) RNA binding;GO:0000287 magnesium ion binding", "go_cellular_component": "GO:0000932 P-body;GO:0005737 cytoplasm", "go_biological_process": "GO:0051301 cell division;GO:0000956 nuclear-transcribed mRNA catabolic process;GO:0010587 miRNA catabolic process;GO:1990074 polyuridylation-dependent mRNA catabolic process;GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZNW9-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8D1IAV6-1", "uniprot_id": [ { "id": "A0A8D1IAV6_PIG", "url": "https://www.uniprot.org/uniprot/A0A8D1IAV6", "type": "external" } ], "mass": 11653.0, "length": 113, "protein_name": "Alpha-synuclein", "gene_name": "SNCA", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SNCA", "gene_names_refseq": "", "protein_names_uniprotkb": "Alpha-synuclein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Also acts as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. This chaperone activity is important to sustain normal SNARE-complex assembly during aging. Also plays a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity., [UniProtKB, UniProtKB]; Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A5G2R2I6", "ec_number_list": [], "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0003779 actin binding;GO:0005543 phospholipid binding;GO:0008047 enzyme activator activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0099512 supramolecular fiber;GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0051585 negative regulation of dopamine uptake involved in synaptic transmission;GO:0051622 negative regulation of norepinephrine uptake;GO:1903285 positive regulation of hydrogen peroxide catabolic process;GO:1904715 negative regulation of chaperone-mediated autophagy;GO:0031623 receptor internalization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8D1IAV6-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A286ZRK2-1", "uniprot_id": [ { "id": "A0A286ZRK2_PIG", "url": "https://www.uniprot.org/uniprot/A0A286ZRK2", "type": "external" } ], "mass": 113105.0, "length": 1027, "protein_name": "Sodium/potassium-transporting ATPase subunit alpha", "gene_name": "ATP1A3", "organism": "Pig", "refseq_name": "sodium/potassium-transporting ATPase subunit alpha-3 isoform X1", "refseq_ac": [ { "id": "XP_020948935", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020948935", "type": "external" } ], "gene_names_uniprotkb": "ATP1A3", "gene_names_refseq": "ATP1A3", "protein_names_uniprotkb": "Sodium/potassium-transporting ATPase subunit alpha", "protein_names_refseq": "sodium/potassium-transporting ATPase subunit alpha-3 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5578775); (R-SSC-936837)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0051087 protein-folding chaperone binding;GO:0001540 amyloid-beta binding;GO:0016887 ATP hydrolysis activity;GO:0030955 potassium ion binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0030424 axon;GO:0043025 neuronal cell body;GO:0031090 organelle membrane", "go_biological_process": "GO:1990535 neuron projection maintenance;GO:0006883 intracellular sodium ion homeostasis;GO:0030007 intracellular potassium ion homeostasis;GO:0036376 sodium ion export across plasma membrane;GO:1990573 potassium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZRK2-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "I3LMB3-1", "uniprot_id": [ { "id": "PLM_PIG", "url": "https://www.uniprot.org/uniprot/I3LMB3", "type": "external" } ], "mass": 9672.0, "length": 87, "protein_name": "Phospholemman", "gene_name": "FXYD1; FXYD7", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "FXYD1; FXYD7; PLM", "gene_names_refseq": "", "protein_names_uniprotkb": "Phospholemman; FXYD domain-containing ion transport regulator 1; Sodium/potassium-transporting ATPase subunit FXYD1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5578775); (R-SSC-936837)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15563542;32543654", "class_list": "", "function": "Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Reduces the apparent affinity for external K(+), an effect that depends on the presence of external Na(+) and voltage. Increases the apparent affinity for intracellular Na(+)., [UniProtKB, UniProtKB]; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0017080 sodium channel regulator activity;GO:0044325 transmembrane transporter binding;GO:0099106 ion channel regulator activity", "go_cellular_component": "GO:0014704 intercalated disc;GO:0016324 apical plasma membrane;GO:0005901 caveola;GO:0042383 sarcolemma;GO:0030315 T-tubule", "go_biological_process": "GO:0006813 potassium ion transport;GO:0006814 sodium ion transport;GO:1903278 positive regulation of sodium ion export across plasma membrane;GO:0010734 negative regulation of protein glutathionylation;GO:0043269 regulation of monoatomic ion transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "I3LMB3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000001.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1SB98-1", "uniprot_id": [ { "id": "F1SB98_PIG", "url": "https://www.uniprot.org/uniprot/F1SB98", "type": "external" } ], "mass": 53405.0, "length": 481, "protein_name": "Beta-secretase 1", "gene_name": "BACE1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "BACE1", "gene_names_refseq": "", "protein_names_uniprotkb": "Beta-secretase 1; 3.4.23.46; Beta-site amyloid precursor protein cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves CHL1., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004190 aspartic-type endopeptidase activity;GO:0001540 amyloid-beta binding;GO:0120283 protein serine/threonine kinase binding", "go_cellular_component": "GO:0005769 early endosome;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0006508 proteolysis;GO:0006509 membrane protein ectodomain proteolysis;GO:0016485 protein processing;GO:0050435 amyloid-beta metabolic process;GO:0043525 positive regulation of neuron apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SB98-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "I3LQW3-1", "uniprot_id": [ { "id": "I3LQW3_PIG", "url": "https://www.uniprot.org/uniprot/I3LQW3", "type": "external" } ], "mass": 57872.0, "length": 529, "protein_name": "Large neutral amino acids transporter small subunit 2", "gene_name": "SLC7A8", "organism": "Pig", "refseq_name": "large neutral amino acids transporter small subunit 2 isoform X1", "refseq_ac": [ { "id": "XP_020954898", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020954898", "type": "external" } ], "gene_names_uniprotkb": "SLC7A8", "gene_names_refseq": "SLC7A8", "protein_names_uniprotkb": "Large neutral amino acids transporter small subunit 2; L-type amino acid transporter 2; Solute carrier family 7 member 8", "protein_names_refseq": "large neutral amino acids transporter small subunit 2 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-352230)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0015297 antiporter activity;GO:0022857 transmembrane transporter activity;GO:0015180 L-alanine transmembrane transporter activity;GO:0015187 glycine transmembrane transporter activity;GO:0015179 L-amino acid transmembrane transporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0016020 membrane;GO:0016324 apical plasma membrane;GO:0031528 microvillus membrane", "go_biological_process": "GO:0015804 neutral amino acid transport;GO:0003333 amino acid transmembrane transport;GO:0035524 proline transmembrane transport;GO:1903801 L-leucine import across plasma membrane;GO:0015827 tryptophan transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LQW3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1S8N5-1", "uniprot_id": [ { "id": "F1S8N5_PIG", "url": "https://www.uniprot.org/uniprot/F1S8N5", "type": "external" } ], "mass": 344716.0, "length": 3138, "protein_name": "Huntingtin", "gene_name": "HTT", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "HTT", "gene_names_refseq": "", "protein_names_uniprotkb": "Huntingtin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "May play a role in microtubule-mediated transport or vesicle function., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Promotes the formation of autophagic vesicles., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0042802 identical protein binding;GO:0031072 heat shock protein binding;GO:0044325 transmembrane transporter binding;GO:0019900 kinase binding;GO:0048487 beta-tubulin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0030424 axon;GO:0045202 synapse;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0009966 regulation of signal transduction;GO:0007017 microtubule-based process;GO:1901526 positive regulation of mitophagy;GO:0043065 positive regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S8N5-1", "record_type": "protein", "filter_code": "0000000.0000100.001000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A5G2REM4-1", "uniprot_id": [ { "id": "A0A5G2REM4_PIG", "url": "https://www.uniprot.org/uniprot/A0A5G2REM4", "type": "external" } ], "mass": 73883.0, "length": 665, "protein_name": "O-acyltransferase", "gene_name": "DGAT1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "DGAT1", "gene_names_refseq": "", "protein_names_uniprotkb": "O-acyltransferase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1482883); (R-SSC-6798695); (R-SSC-75109)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004144 diacylglycerol O-acyltransferase activity;GO:0050252 retinol O-fatty-acyltransferase activity;GO:0042802 identical protein binding;GO:0003846 2-acylglycerol O-acyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0019432 triglyceride biosynthetic process;GO:0046339 diacylglycerol metabolic process;GO:0034379 very-low-density lipoprotein particle assembly;GO:0055089 fatty acid homeostasis;GO:0035336 long-chain fatty-acyl-CoA metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2REM4-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1S848-1", "uniprot_id": [ { "id": "F1S848_PIG", "url": "https://www.uniprot.org/uniprot/F1S848", "type": "external" } ], "mass": 65113.0, "length": 562, "protein_name": "Cytosolic purine 5'-nucleotidase", "gene_name": "NT5C2", "organism": "Pig", "refseq_name": "cytosolic purine 5'-nucleotidase", "refseq_ac": [ { "id": "XP_001929313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929313", "type": "external" } ], "gene_names_uniprotkb": "NT5C2", "gene_names_refseq": "NT5C2", "protein_names_uniprotkb": "Cytosolic purine 5'-nucleotidase; 2.7.1.77; 3.1.3.5; 3.1.3.99; Cytosolic nucleoside phosphotransferase 5'N", "protein_names_refseq": "cytosolic purine 5'-nucleotidase", "tax_id": 9823, "disease": "", "pathway": " (ssc:100154612); (R-SSC-2161541); (R-SSC-74259); (R-SSC-9755088)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Broad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates. In addition, possesses a phosphotransferase activity by which it can transfer a phosphate from a donor nucleoside monophosphate to an acceptor nucleoside, preferably inosine, deoxyinosine and guanosine. Has the highest activities for IMP and GMP followed by dIMP, dGMP and XMP. Could also catalyze the transfer of phosphates from pyrimidine monophosphates but with lower efficiency. Through these activities regulates the purine nucleoside/nucleotide pools within the cell., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008253 5'-nucleotidase activity;GO:0050146 nucleoside phosphotransferase activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0046054 dGMP metabolic process;GO:0046037 GMP metabolic process;GO:0050689 negative regulation of defense response to virus by host;GO:0070936 protein K48-linked ubiquitination;GO:0000255 allantoin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S848-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RX70-1", "uniprot_id": [ { "id": "F1RX70_PIG", "url": "https://www.uniprot.org/uniprot/F1RX70", "type": "external" } ], "mass": 165758.0, "length": 1466, "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "WRN", "gene_names_refseq": "", "protein_names_uniprotkb": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN; 5.6.2.4", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-174414); (R-SSC-174437); (R-SSC-5685938); (R-SSC-5685942); (R-SSC-5693537); (R-SSC-5693568); (R-SSC-5693579); (R-SSC-5693607); (R-SSC-5693616); (R-SSC-6804756); (R-SSC-69473)", "pathway_count": 11, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0043138 3'-5' DNA helicase activity;GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008408 3'-5' exonuclease activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000781 chromosome, telomeric region;GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0000723 telomere maintenance;GO:0006260 DNA replication;GO:0032392 DNA geometric change", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RX70-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "I3L629-1", "uniprot_id": [ { "id": "I3L629_PIG", "url": "https://www.uniprot.org/uniprot/I3L629", "type": "external" } ], "mass": 55884.0, "length": 503, "protein_name": "N-fatty-acyl-amino acid synthase/hydrolase PM20D1", "gene_name": "LOC100519130", "organism": "Pig", "refseq_name": "N-fatty-acyl-amino acid synthase/hydrolase PM20D1 isoform X1", "refseq_ac": [ { "id": "XP_005654890", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005654890", "type": "external" } ], "gene_names_uniprotkb": "LOC100519130", "gene_names_refseq": "LOC100519130", "protein_names_uniprotkb": "N-fatty-acyl-amino acid synthase/hydrolase PM20D1; 3.5.1.114; 3.5.1.14; Peptidase M20 domain-containing protein 1", "protein_names_refseq": "N-fatty-acyl-amino acid synthase/hydrolase PM20D1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100519130); (R-SSC-9673163)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Secreted enzyme that regulates the endogenous N-fatty acyl amino acid (NAAs) tissue and circulating levels by functioning as a bidirectional NAA synthase/hydrolase. It condenses free fatty acids and free amino acids to generate NAAs and bidirectionally catalyzes the reverse hydrolysis reaction. Some of these NAAs stimulate oxidative metabolism via mitochondrial uncoupling, increasing energy expenditure in a UPC1-independent manner. Thereby, this secreted protein may indirectly regulate whole body energy expenditure. PM20D1 circulates in tight association with both low- and high-density (LDL and HDL,respectively) lipoprotein particles., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004046 aminoacylase activity;GO:0046872 metal ion binding;GO:0008233 peptidase activity;GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006508 proteolysis;GO:0006629 lipid metabolic process;GO:0006520 amino acid metabolic process;GO:0043604 amide biosynthetic process;GO:0043605 amide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3L629-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8D1YIJ1-1", "uniprot_id": [ { "id": "A0A8D1YIJ1_PIG", "url": "https://www.uniprot.org/uniprot/A0A8D1YIJ1", "type": "external" } ], "mass": 92250.0, "length": 829, "protein_name": "Transitional endoplasmic reticulum ATPase", "gene_name": "VCP", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "VCP", "gene_names_refseq": "", "protein_names_uniprotkb": "Transitional endoplasmic reticulum ATPase; 15S Mg(2+)-ATPase p97 subunit; 3.6.4.6; Valosin-containing protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-110320); (R-SSC-3371511); (R-SSC-382556); (R-SSC-532668); (R-SSC-5358346); (R-SSC-5689877); (R-SSC-5689896); (R-SSC-6798695); (R-SSC-8876725); (R-SSC-8951664); (R-SSC-9013407); (R-SSC-9755511); (R-SSC-9931269)", "pathway_count": 13, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A5G2RLZ5", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0016887 ATP hydrolysis activity;GO:0008289 lipid binding;GO:0036435 K48-linked polyubiquitin modification-dependent protein binding", "go_cellular_component": "GO:1990730 VCP-NSFL1C complex;GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex;GO:0005634 nucleus;GO:0005829 cytosol;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006281 DNA repair;GO:0006914 autophagy;GO:0030970 retrograde protein transport, ER to cytosol;GO:0097352 autophagosome maturation;GO:2001171 positive regulation of ATP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8D1YIJ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RSM7-1", "uniprot_id": [ { "id": "F1RSM7_PIG", "url": "https://www.uniprot.org/uniprot/F1RSM7", "type": "external" } ], "mass": 56624.0, "length": 526, "protein_name": "Heat shock transcription factor 1", "gene_name": "HSF1", "organism": "Pig", "refseq_name": "heat shock factor protein 1 isoform X13", "refseq_ac": [ { "id": "XP_005655367", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005655367", "type": "external" } ], "gene_names_uniprotkb": "HSF1", "gene_names_refseq": "HSF1", "protein_names_uniprotkb": "Heat shock transcription factor 1", "protein_names_refseq": "heat shock factor protein 1 isoform X13", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-3371453); (R-SSC-3371511); (R-SSC-3371568); (R-SSC-3371571); (R-SSC-9841251)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A481B9E5", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0043565 sequence-specific DNA binding;GO:0019901 protein kinase binding;GO:0042802 identical protein binding;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0097165 nuclear stress granule;GO:0005813 centrosome;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0010628 positive regulation of gene expression;GO:0045931 positive regulation of mitotic cell cycle;GO:1900034 regulation of cellular response to heat;GO:0000165 MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RSM7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A5G2RCE3-1", "uniprot_id": [ { "id": "A0A5G2RCE3_PIG", "url": "https://www.uniprot.org/uniprot/A0A5G2RCE3", "type": "external" } ], "mass": 312896.0, "length": 2746, "protein_name": "Inositol 1,4,5-trisphosphate receptor", "gene_name": "ITPR1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "ITPR1", "gene_names_refseq": "", "protein_names_uniprotkb": "Inositol 1,4,5-trisphosphate receptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-114508); (R-SSC-139853); (R-SSC-381676); (R-SSC-418457); (R-SSC-5578775); (R-SSC-983695)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0070679 inositol 1,4,5 trisphosphate binding;GO:0005220 inositol 1,4,5-trisphosphate-gated calcium channel activity;GO:0019904 protein domain specific binding;GO:0042803 protein homodimerization activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005791 rough endoplasmic reticulum;GO:0030141 secretory granule;GO:0005789 endoplasmic reticulum membrane;GO:0030658 transport vesicle membrane;GO:0031094 platelet dense tubular network", "go_biological_process": "GO:0051209 release of sequestered calcium ion into cytosol;GO:0050849 negative regulation of calcium-mediated signaling;GO:0042045 epithelial fluid transport;GO:0007207 phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway;GO:0043065 positive regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2RCE3-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1SS24-1", "uniprot_id": [ { "id": "F1SS24_PIG", "url": "https://www.uniprot.org/uniprot/F1SS24", "type": "external" } ], "mass": 272079.0, "length": 2476, "protein_name": "Fibronectin", "gene_name": "FN1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "FN1", "gene_names_refseq": "", "protein_names_uniprotkb": "Fibronectin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-114608); (R-SSC-1474228); (R-SSC-1566977); (R-SSC-202733); (R-SSC-216083); (R-SSC-3000170); (R-SSC-3000178); (R-SSC-354192); (R-SSC-354194); (R-SSC-372708); (R-SSC-381426); (R-SSC-5674135); (R-SSC-8957275); (R-SSC-9634597); (R-SSC-9860927)", "pathway_count": 15, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Secreted by contracting muscle, induces liver autophagy, a degradative pathway for nutrient mobilization and damage removal, and systemic insulin sensitization via hepatic ITGA5:ITGB1 integrin receptor signaling., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0002020 protease binding;GO:0005178 integrin binding;GO:0016504 peptidase activator activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0070062 extracellular exosome;GO:0016324 apical plasma membrane;GO:0005577 fibrinogen complex;GO:0005604 basement membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0006953 acute-phase response;GO:0008360 regulation of cell shape;GO:0071635 negative regulation of transforming growth factor beta production;GO:0051702 biological process involved in interaction with symbiont", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SS24-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RGH8-1", "uniprot_id": [ { "id": "F1RGH8_PIG", "url": "https://www.uniprot.org/uniprot/F1RGH8", "type": "external" } ], "mass": 60028.0, "length": 566, "protein_name": "[tau protein] kinase", "gene_name": "GSK3A", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "GSK3A", "gene_names_refseq": "", "protein_names_uniprotkb": "[tau protein] kinase; 2.7.11.26", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0050321 tau-protein kinase activity;GO:0034236 protein kinase A catalytic subunit binding;GO:0004674 protein serine/threonine kinase activity;GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0030424 axon", "go_biological_process": "GO:0005977 glycogen metabolic process;GO:0009968 negative regulation of signal transduction;GO:0051093 negative regulation of developmental process;GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development;GO:0046627 negative regulation of insulin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RGH8-1", "record_type": "protein", "filter_code": "0000000.0000100.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "I3LT92-1", "uniprot_id": [ { "id": "I3LT92_PIG", "url": "https://www.uniprot.org/uniprot/I3LT92", "type": "external" } ], "mass": 84880.0, "length": 757, "protein_name": "DNA mismatch repair protein MLH1", "gene_name": "MLH1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "MLH1", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA mismatch repair protein MLH1; DNA mismatch repair protein Mlh1; MutL protein homolog 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5358565)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8D0UUS1", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0030983 mismatched DNA binding;GO:0140664 ATP-dependent DNA damage sensor activity;GO:0003682 chromatin binding", "go_cellular_component": "GO:0032300 mismatch repair complex;GO:0005654 nucleoplasm;GO:0005694 chromosome;GO:0032389 MutLalpha complex", "go_biological_process": "GO:0006298 mismatch repair;GO:0000710 meiotic mismatch repair;GO:0016446 somatic hypermutation of immunoglobulin genes", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LT92-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RWC5-1", "uniprot_id": [ { "id": "F1RWC5_PIG", "url": "https://www.uniprot.org/uniprot/F1RWC5", "type": "external" } ], "mass": 109762.0, "length": 963, "protein_name": "Kinesin-like protein", "gene_name": "KIF5B", "organism": "Pig", "refseq_name": "kinesin-1 heavy chain", "refseq_ac": [ { "id": "XP_020920464", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920464", "type": "external" } ], "gene_names_uniprotkb": "KIF5B", "gene_names_refseq": "KIF5B", "protein_names_uniprotkb": "Kinesin-like protein", "protein_names_refseq": "kinesin-1 heavy chain", "tax_id": 9823, "disease": "", "pathway": " (ssc:595132); (R-SSC-2132295); (R-SSC-5625970); (R-SSC-6811434); (R-SSC-983189)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "K9J4S7", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity;GO:0042802 identical protein binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005874 microtubule;GO:1904115 axon cytoplasm;GO:0032991 protein-containing complex;GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0007292 female gamete generation;GO:0007097 nuclear migration;GO:0048489 synaptic vesicle transport;GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity;GO:0098957 anterograde axonal transport of mitochondrion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RWC5-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A5K1TZ96-1", "uniprot_id": [ { "id": "A0A5K1TZ96_PIG", "url": "https://www.uniprot.org/uniprot/A0A5K1TZ96", "type": "external" } ], "mass": 54105.0, "length": 476, "protein_name": "Hyaluronidase", "gene_name": "HYAL2", "organism": "Pig", "refseq_name": "hyaluronidase-2 precursor", "refseq_ac": [ { "id": "XP_005669631", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005669631", "type": "external" } ], "gene_names_uniprotkb": "HYAL2", "gene_names_refseq": "HYAL2", "protein_names_uniprotkb": "Hyaluronidase; 3.2.1.35", "protein_names_refseq": "hyaluronidase-2 precursor; hyaluronoglucosaminidase 2; lysosomal hyaluronidase", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2142845); (R-SSC-2160916)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes hyaluronan degradation into small fragments that are endocytosed and degraded in lysosomes by HYAL1 and exoglycosidases. Essential for the breakdown of extracellular matrix hyaluronan., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004415 hyalurononglucosaminidase activity;GO:0003713 transcription coactivator activity;GO:0001618 virus receptor activity;GO:0030971 receptor tyrosine kinase binding;GO:0050431 transforming growth factor beta binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098552 side of membrane;GO:0005829 cytosol;GO:0045121 membrane raft;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0042307 positive regulation of protein import into nucleus;GO:0010764 negative regulation of fibroblast migration;GO:0071493 cellular response to UV-B;GO:0042117 monocyte activation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5K1TZ96-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000011000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8D1LRN3-1", "uniprot_id": [ { "id": "A0A8D1LRN3_PIG", "url": "https://www.uniprot.org/uniprot/A0A8D1LRN3", "type": "external" } ], "mass": 31391.0, "length": 278, "protein_name": "Caspase-3", "gene_name": "CASP3", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CASP3", "gene_names_refseq": "", "protein_names_uniprotkb": "Caspase-3; 3.4.22.56", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-111459); (R-SSC-111465); (R-SSC-111469); (R-SSC-140342); (R-SSC-2028269); (R-SSC-205025); (R-SSC-264870); (R-SSC-351906); (R-SSC-418889); (R-SSC-449836); (R-SSC-5620971); (R-SSC-9960519); (R-SSC-9960525)", "pathway_count": 13, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A5G2QQP0", "ec_number_list": [], "go_molecular_function": "GO:0004197 cysteine-type endopeptidase activity;GO:0008047 enzyme activator activity;GO:0004190 aspartic-type endopeptidase activity;GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005829 cytosol;GO:0014069 postsynaptic density", "go_biological_process": "GO:0006508 proteolysis;GO:0097194 execution phase of apoptosis;GO:0051604 protein maturation;GO:0006915 apoptotic process;GO:0016485 protein processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8D1LRN3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "K7GQ93-1", "uniprot_id": [ { "id": "K7GQ93_PIG", "url": "https://www.uniprot.org/uniprot/K7GQ93", "type": "external" } ], "mass": 65208.0, "length": 579, "protein_name": "Glypican-3", "gene_name": "GPC3", "organism": "Pig", "refseq_name": "glypican-3", "refseq_ac": [ { "id": "XP_013841903", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_013841903", "type": "external" } ], "gene_names_uniprotkb": "GPC3", "gene_names_refseq": "GPC3", "protein_names_uniprotkb": "Glypican-3", "protein_names_refseq": "glypican-3", "tax_id": 9823, "disease": "", "pathway": " (ssc:100516171); (R-SSC-1971475); (R-SSC-2022928); (R-SSC-2024096); (R-SSC-381426); (R-SSC-8957275); (R-SSC-975634); (R-SSC-9769735); (R-SSC-9769739)", "pathway_count": 9, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Cell surface proteoglycan., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0060422 peptidyl-dipeptidase inhibitor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031012 extracellular matrix;GO:0098552 side of membrane;GO:0009986 cell surface;GO:0005764 lysosome", "go_biological_process": "GO:0009966 regulation of signal transduction;GO:0016477 cell migration;GO:0090263 positive regulation of canonical Wnt signaling pathway;GO:0072138 mesenchymal cell proliferation involved in ureteric bud development;GO:2000050 regulation of non-canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GQ93-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F2Z543-1", "uniprot_id": [ { "id": "F2Z543_PIG", "url": "https://www.uniprot.org/uniprot/F2Z543", "type": "external" } ], "mass": 29804.0, "length": 272, "protein_name": "Prohibitin", "gene_name": "PHB1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PHB1", "gene_names_refseq": "", "protein_names_uniprotkb": "Prohibitin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5673000); (R-SSC-8949664)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "In the nucleus, acts as a transcription coregulator, enhances promoter binding by TP53, a transcription factor it activates, but reduces the promoter binding by E2F1, a transcription factor it represses. Interacts with STAT3 to affect IL17 secretion in T-helper Th17 cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; In the plasma membrane, cooperates with CD86 to mediate CD86-signaling in B lymphocytes that regulates the level of IgG1 produced through the activation of distal signaling intermediates. Upon CD40 engagement, required to activate NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors in the nucleus. Plays a role in adipose tissue and glucose homeostasis in a sex-specific manner. Contributes to pulmonary vascular remodeling by accelerating proliferation of pulmonary arterial smooth muscle cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0003714 transcription corepressor activity;GO:0042826 histone deacetylase binding;GO:0001851 complement component C3b binding;GO:0001850 complement component C3a binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0005769 early endosome;GO:0005886 plasma membrane", "go_biological_process": "GO:0071897 DNA biosynthetic process;GO:0032740 positive regulation of interleukin-17 production;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0008285 negative regulation of cell population proliferation;GO:0045745 positive regulation of G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F2Z543-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A5G2R274-1", "uniprot_id": [ { "id": "A0A5G2R274_PIG", "url": "https://www.uniprot.org/uniprot/A0A5G2R274", "type": "external" } ], "mass": 39133.0, "length": 347, "protein_name": "Aldo-keto reductase family 1 member B1", "gene_name": "AKR1B1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AKR1B1", "gene_names_refseq": "", "protein_names_uniprotkb": "Aldo-keto reductase family 1 member B1; 1.1.1.21; 1.1.1.300; 1.1.1.372; 1.1.1.54; Aldehyde reductase; Aldose reductase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-196108); (R-SSC-5652227)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity;GO:0047655 allyl-alcohol dehydrogenase activity;GO:0004032 aldose reductase (NADPH) activity;GO:0001758 retinal dehydrogenase (NAD+) activity;GO:0043795 glyceraldehyde oxidoreductase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006060 sorbitol metabolic process;GO:0044597 daunorubicin metabolic process;GO:0044598 doxorubicin metabolic process;GO:0046370 fructose biosynthetic process;GO:0071475 cellular hyperosmotic salinity response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2R274-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "K7GND3-1", "uniprot_id": [ { "id": "K7GND3_PIG", "url": "https://www.uniprot.org/uniprot/K7GND3", "type": "external" } ], "mass": 149741.0, "length": 1384, "protein_name": "ATP-dependent RNA helicase A", "gene_name": "DHX9", "organism": "Pig", "refseq_name": "ATP-dependent RNA helicase A isoform X1", "refseq_ac": [ { "id": "XP_020919437", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020919437", "type": "external" } ], "gene_names_uniprotkb": "DHX9", "gene_names_refseq": "DHX9", "protein_names_uniprotkb": "ATP-dependent RNA helicase A; 3.6.4.13; DEAH box protein 9; Nuclear DNA helicase II", "protein_names_refseq": "ATP-dependent RNA helicase A isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100514066); (R-SSC-1810476); (R-SSC-3134963); (R-SSC-72163); (R-SSC-9770562); (R-SSC-9833482)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003676 nucleic acid binding;GO:0003724 RNA helicase activity;GO:0033679 3'-5' DNA/RNA helicase activity", "go_cellular_component": "GO:0005726 perichromatin fibrils;GO:0097165 nuclear stress granule;GO:0005730 nucleolus;GO:0005813 centrosome;GO:0005829 cytosol", "go_biological_process": "GO:0071360 cellular response to exogenous dsRNA;GO:0032727 positive regulation of interferon-alpha production;GO:1903608 protein localization to cytoplasmic stress granule;GO:0039695 DNA-templated viral transcription;GO:0046833 positive regulation of RNA export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GND3-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1STX7-1", "uniprot_id": [ { "id": "F1STX7_PIG", "url": "https://www.uniprot.org/uniprot/F1STX7", "type": "external" } ], "mass": 94857.0, "length": 875, "protein_name": "Lysine-specific histone demethylase", "gene_name": "KDM1A", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "KDM1A", "gene_names_refseq": "", "protein_names_uniprotkb": "Lysine-specific histone demethylase; 1.14.99.66", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-3214815); (R-SSC-3214842); (R-SSC-5625886); (R-SSC-9018519); (R-SSC-9764725); (R-SSC-983231)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Histone demethylase that can demethylate both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3K4me on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Neuron-specific histone demethylase that demethylates mono- and dimethylated 'Lys-20' of histone H4 (H4K20me1 and H4K20me2), a chromatin repressive mark. This demethylation is crucial for the initiation and elongation of neuronal activity-regulated genes, required for spatial learning and memory. Mediates H3K9me2 demethylation through cooperation with the supervillin protein (SVIL), and this H3K9 demethylase activity is essential for regulating gene expression during neuronal differentiation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0003723 RNA binding;GO:0019899 enzyme binding;GO:0050660 flavin adenine dinucleotide binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0035097 histone methyltransferase complex;GO:1990391 DNA repair complex;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045597 positive regulation of cell differentiation;GO:2000179 positive regulation of neural precursor cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1STX7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RHN3-1", "uniprot_id": [ { "id": "F1RHN3_PIG", "url": "https://www.uniprot.org/uniprot/F1RHN3", "type": "external" } ], "mass": 30043.0, "length": 270, "protein_name": "Catechol O-methyltransferase", "gene_name": "COMT", "organism": "Pig", "refseq_name": "catechol O-methyltransferase isoform X1", "refseq_ac": [ { "id": "XP_005670993", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005670993", "type": "external" } ], "gene_names_uniprotkb": "COMT", "gene_names_refseq": "COMT", "protein_names_uniprotkb": "Catechol O-methyltransferase; 2.1.1.6", "protein_names_refseq": "catechol O-methyltransferase isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-156581); (R-SSC-379397); (R-SSC-379398)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A5G2QXV8", "ec_number_list": [], "go_molecular_function": "GO:0016206 catechol O-methyltransferase activity;GO:0000287 magnesium ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0016020 membrane;GO:0030424 axon", "go_biological_process": "GO:0006584 catecholamine metabolic process;GO:0032259 methylation;GO:0032502 developmental process;GO:0042417 dopamine metabolic process;GO:0042424 catecholamine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RHN3-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RSE6-1", "uniprot_id": [ { "id": "F1RSE6_PIG", "url": "https://www.uniprot.org/uniprot/F1RSE6", "type": "external" } ], "mass": 465283.0, "length": 4136, "protein_name": "DNA-dependent protein kinase catalytic subunit", "gene_name": "PRKDC", "organism": "Pig", "refseq_name": "DNA-dependent protein kinase catalytic subunit isoform X1", "refseq_ac": [ { "id": "XP_020945078", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020945078", "type": "external" } ], "gene_names_uniprotkb": "PRKDC", "gene_names_refseq": "PRKDC", "protein_names_uniprotkb": "DNA-dependent protein kinase catalytic subunit; 2.7.11.1", "protein_names_refseq": "DNA-dependent protein kinase catalytic subunit isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100156379); (R-SSC-5693571); (R-SSC-8866654)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0004677 DNA-dependent protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0019899 enzyme binding;GO:0019904 protein domain specific binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex;GO:0000785 chromatin", "go_biological_process": "GO:0042254 ribosome biogenesis;GO:0006303 double-strand break repair via nonhomologous end joining;GO:0050678 regulation of epithelial cell proliferation;GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining;GO:0032869 cellular response to insulin stimulus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RSE6-1", "record_type": "protein", "filter_code": "0000000.0000101.001000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8W4FKK7-1", "uniprot_id": [ { "id": "A0A8W4FKK7_PIG", "url": "https://www.uniprot.org/uniprot/A0A8W4FKK7", "type": "external" } ], "mass": 97420.0, "length": 885, "protein_name": "Tyrosine-protein kinase receptor UFO", "gene_name": "AXL", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "AXL", "gene_names_refseq": "", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor UFO; 2.7.10.1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-4420097)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity;GO:0001618 virus receptor activity;GO:0001786 phosphatidylserine binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005615 extracellular space;GO:0009986 cell surface;GO:0043235 receptor complex", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0045087 innate immune response;GO:0006909 phagocytosis;GO:0009967 positive regulation of signal transduction;GO:0001818 negative regulation of cytokine production", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FKK7-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A5G2RK10-1", "uniprot_id": [ { "id": "A0A5G2RK10_PIG", "url": "https://www.uniprot.org/uniprot/A0A5G2RK10", "type": "external" } ], "mass": 95126.0, "length": 867, "protein_name": "Axin-1", "gene_name": "AXIN1", "organism": "Pig", "refseq_name": "axin-1 isoform X5", "refseq_ac": [ { "id": "XP_020942590", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020942590", "type": "external" } ], "gene_names_uniprotkb": "AXIN1", "gene_names_refseq": "AXIN1", "protein_names_uniprotkb": "Axin-1; 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Mediates cell adhesion to the extracellular matrix via integrin-dependent signaling, by mediating angiotensin-2-induced activation of integrin beta-1 (ITGB1) in cardiac fibroblasts. Phosphorylates MARCKS, which phosphorylates and activates PTK2/FAK, leading to the spread of cardiomyocytes. Involved in the control of the directional transport of ITGB1 in mesenchymal cells by phosphorylating vimentin (VIM), an intermediate filament (IF) protein. In epithelial cells, associates with and phosphorylates keratin-8 (KRT8), which induces targeting of desmoplakin at desmosomes and regulates cell-cell contact. 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"GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0045087 innate immune response;GO:0046330 positive regulation of JNK cascade;GO:0051607 defense response to virus;GO:0032722 positive regulation of chemokine production", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RZN4-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F6QAP1-1", "uniprot_id": [ { "id": "F6QAP1_PIG", "url": "https://www.uniprot.org/uniprot/F6QAP1", "type": "external" } ], "mass": 89170.0, "length": 815, "protein_name": "Catenin beta 1", "gene_name": "CTNNB1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "CTNNB1", "gene_names_refseq": "", "protein_names_uniprotkb": "Catenin beta 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-195253); (R-SSC-196299); (R-SSC-201681); (R-SSC-201722); (R-SSC-3134973); (R-SSC-351906); (R-SSC-3769402); (R-SSC-4086398); (R-SSC-418990); (R-SSC-4641262); (R-SSC-5218920); (R-SSC-525793); (R-SSC-5626467); (R-SSC-8951430); (R-SSC-9762292); (R-SSC-9764561); (R-SSC-9766229); (R-SSC-9768727); (R-SSC-9825892); (R-SSC-9943962); (R-SSC-9958810); (R-SSC-9958825)", "pathway_count": 22, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0045296 cadherin binding;GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0005102 signaling receptor binding;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005912 adherens junction;GO:0016020 membrane;GO:0098978 glutamatergic synapse;GO:0098831 presynaptic active zone cytoplasmic component", "go_biological_process": "GO:0007155 cell adhesion;GO:0090279 regulation of calcium ion import;GO:0030997 regulation of centriole-centriole cohesion;GO:1904888 cranial skeletal system development;GO:0097091 synaptic vesicle clustering", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F6QAP1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "I3LR30-1", "uniprot_id": [ { "id": "I3LR30_PIG", "url": "https://www.uniprot.org/uniprot/I3LR30", "type": "external" } ], "mass": 54744.0, "length": 475, "protein_name": "CAAX prenyl protease", "gene_name": "ZMPSTE24", "organism": "Pig", "refseq_name": "CAAX prenyl protease 1 homolog isoform X1", "refseq_ac": [ { "id": "XP_020951671", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020951671", "type": "external" } ], "gene_names_uniprotkb": "ZMPSTE24", "gene_names_refseq": "ZMPSTE24", "protein_names_uniprotkb": "CAAX prenyl protease; 3.4.24.84", "protein_names_refseq": "CAAX prenyl protease 1 homolog isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:106507628)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Proteolytically removes the C-terminal three residues of farnesylated proteins., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:0071586 CAAX-box protein processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LR30-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RJ64-1", "uniprot_id": [ { "id": "F1RJ64_PIG", "url": "https://www.uniprot.org/uniprot/F1RJ64", "type": "external" } ], "mass": 130483.0, "length": 1138, "protein_name": "Diaphanous related formin 3", "gene_name": "DIAPH3", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "DIAPH3", "gene_names_refseq": "", "protein_names_uniprotkb": "Diaphanous related formin 3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5663220); (R-SSC-8980692); (R-SSC-9013026); (R-SSC-9013106); (R-SSC-9013148); (R-SSC-9013149); (R-SSC-9013404); (R-SSC-9013406); (R-SSC-9013408); (R-SSC-9013423); (R-SSC-9035034)", "pathway_count": 11, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003779 actin binding;GO:0031267 small GTPase binding;GO:0008017 microtubule binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005884 actin filament;GO:0005815 microtubule organizing center", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0030041 actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RJ64-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8D1IV93-1", "uniprot_id": [ { "id": "A0A8D1IV93_PIG", "url": "https://www.uniprot.org/uniprot/A0A8D1IV93", "type": "external" } ], "mass": 195287.0, "length": 1709, "protein_name": "Ras GTPase-activating-like protein IQGAP1", "gene_name": "IQGAP1", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "IQGAP1", "gene_names_refseq": "", "protein_names_uniprotkb": "Ras GTPase-activating-like protein IQGAP1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-373753); (R-SSC-5626467); (R-SSC-5674135); (R-SSC-6798695); (R-SSC-8980692); (R-SSC-9013106); (R-SSC-9013148); (R-SSC-9013149); (R-SSC-9013404); (R-SSC-9013406); (R-SSC-9013420); (R-SSC-9013424)", "pathway_count": 12, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Recruited to the cell cortex by interaction with ILK which allows it to cooperate with its effector DIAPH1 to locally stabilize microtubules and allow stable insertion of caveolae into the plasma membrane. Binds to activated CDC42 but does not stimulate its GTPase activity. Associates with calmodulin. May promote neurite outgrowth. May play a possible role in cell cycle regulation by contributing to cell cycle progression after DNA replication arrest., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1RMJ4", "ec_number_list": [], "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0005096 GTPase activator activity;GO:0005516 calmodulin binding;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005874 microtubule;GO:0005911 cell-cell junction;GO:0005925 focal adhesion;GO:0005938 cell cortex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0032956 regulation of actin cytoskeleton organization;GO:0043410 positive regulation of MAPK cascade;GO:0071277 cellular response to calcium ion;GO:0007346 regulation of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8D1IV93-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1S3Y7-1", "uniprot_id": [ { "id": "F1S3Y7_PIG", "url": "https://www.uniprot.org/uniprot/F1S3Y7", "type": "external" } ], "mass": 147321.0, "length": 1336, "protein_name": "Xanthine dehydrogenase/oxidase", "gene_name": "XDH", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "XDH", "gene_names_refseq": "", "protein_names_uniprotkb": "Xanthine dehydrogenase/oxidase; 1.17.1.4; 1.17.3.2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-74259); (R-SSC-8851680); (R-SSC-9748787)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005506 iron ion binding;GO:0071949 FAD binding;GO:0051537 2 iron, 2 sulfur cluster binding;GO:0016491 oxidoreductase activity;GO:0043546 molybdopterin cofactor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005777 peroxisome;GO:0005615 extracellular space;GO:0005829 cytosol;GO:0016529 sarcoplasmic reticulum", "go_biological_process": "GO:0006154 adenosine catabolic process;GO:0006157 deoxyadenosine catabolic process;GO:0006196 AMP catabolic process;GO:0009115 xanthine catabolic process;GO:0006147 guanine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S3Y7-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RJS6-1", "uniprot_id": [ { "id": "F1RJS6_PIG", "url": "https://www.uniprot.org/uniprot/F1RJS6", "type": "external" } ], "mass": 115839.0, "length": 1009, "protein_name": "Protein-tyrosine kinase 2-beta", "gene_name": "PTK2B", "organism": "Pig", "refseq_name": "protein-tyrosine kinase 2-beta isoform X7", "refseq_ac": [ { "id": "XP_001926033", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001926033", "type": "external" } ], "gene_names_uniprotkb": "PTK2B", "gene_names_refseq": "PTK2B", "protein_names_uniprotkb": "Protein-tyrosine kinase 2-beta; 2.7.10.2; Calcium-dependent tyrosine kinase; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; Focal adhesion kinase 2; Proline-rich tyrosine kinase 2", "protein_names_refseq": "protein-tyrosine kinase 2-beta isoform X7", "tax_id": 9823, "disease": "", "pathway": " (ssc:100157507); (R-SSC-391160); (R-SSC-4420097); (R-SSC-9013420); (R-SSC-9020558)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "K7GLY6", "ec_number_list": [], "go_molecular_function": "GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0005938 cell cortex;GO:0030027 lamellipodium", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0008284 positive regulation of cell population proliferation;GO:0030335 positive regulation of cell migration;GO:0043066 negative regulation of apoptotic process;GO:0051247 positive regulation of protein metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RJS6-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1SUV3-1", "uniprot_id": [ { "id": "F1SUV3_PIG", "url": "https://www.uniprot.org/uniprot/F1SUV3", "type": "external" } ], "mass": 105934.0, "length": 945, "protein_name": "Phosphodiesterase", "gene_name": "PDE2A", "organism": "Pig", "refseq_name": "cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X3", "refseq_ac": [ { "id": "XP_003482605", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003482605", "type": "external" } ], "gene_names_uniprotkb": "PDE2A", "gene_names_refseq": "PDE2A", "protein_names_uniprotkb": "Phosphodiesterase; 3.1.4.-", "protein_names_refseq": "cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X3", "tax_id": 9823, "disease": "", "pathway": " (ssc:100737701); (R-SSC-418457); (R-SSC-418555)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Regulates mitochondrial cAMP levels and respiration. Involved in the regulation of mitochondria morphology/dynamics and apoptotic cell death via local modulation of cAMP/PKA signaling in the mitochondrion, including the monitoring of local cAMP levels at the outer mitochondrial membrane and of PKA-dependent phosphorylation of DNM1L., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; cGMP-activated cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP. 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The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, 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"0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RX16-1", "uniprot_id": [ { "id": "F1RX16_PIG", "url": "https://www.uniprot.org/uniprot/F1RX16", "type": "external" } ], "mass": 73241.0, "length": 662, "protein_name": "RNA helicase", "gene_name": "DDX3X", "organism": "Pig", "refseq_name": "ATP-dependent RNA helicase DDX3X isoform X1", "refseq_ac": [ { "id": "XP_005673618", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005673618", "type": "external" } ], "gene_names_uniprotkb": "DDX3X", "gene_names_refseq": "DDX3X", "protein_names_uniprotkb": "RNA helicase; 3.6.4.13", "protein_names_refseq": "ATP-dependent RNA helicase DDX3X isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-6798695)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, 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"secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003724 RNA helicase activity;GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005813 centrosome;GO:0005886 plasma membrane", "go_biological_process": "GO:0032727 positive regulation of interferon-alpha production;GO:1903608 protein localization to cytoplasmic stress granule;GO:0007059 chromosome segregation;GO:0010629 negative regulation of gene expression;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RX16-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1SPH6-1", "uniprot_id": [ { "id": "F1SPH6_PIG", "url": "https://www.uniprot.org/uniprot/F1SPH6", "type": "external" } ], "mass": 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"go_biological_process": "GO:0007611 learning or memory;GO:0009409 response to cold;GO:0042391 regulation of membrane potential;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0095500 acetylcholine receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SNR6-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "K7GQT5-1", "uniprot_id": [ { "id": "K7GQT5_PIG", "url": "https://www.uniprot.org/uniprot/K7GQT5", "type": "external" } ], "mass": 49571.0, "length": 454, "protein_name": "Forkhead box protein P3", "gene_name": "FOXP3", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "FOXP3", "gene_names_refseq": "", "protein_names_uniprotkb": "Forkhead box protein P3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-8877330)", "pathway_count": 1, "publication_count": 1, 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"reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0043565 sequence-specific DNA binding;GO:0051525 NFAT protein binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0032693 negative regulation of interleukin-10 production;GO:0002725 negative regulation of T cell cytokine production;GO:0032700 negative regulation of interleukin-17 production;GO:0032703 negative regulation of interleukin-2 production", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GQT5-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "I3LK11-1", "uniprot_id": [ { "id": "I3LK11_PIG", "url": "https://www.uniprot.org/uniprot/I3LK11", "type": "external" } ], "mass": 18120.0, "length": 158, "protein_name": "Intraflagellar transport 20", "gene_name": "IFT20", "organism": "Pig", "refseq_name": "intraflagellar transport protein 20 homolog isoform X1", "refseq_ac": [ { "id": "XP_003358215", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003358215", "type": "external" } ], "gene_names_uniprotkb": "IFT20", "gene_names_refseq": "IFT20", "protein_names_uniprotkb": "Intraflagellar transport 20", "protein_names_refseq": "intraflagellar transport protein 20 homolog isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100623555); (R-SSC-5620924)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0031267 small GTPase binding;GO:0002046 opsin binding", "go_cellular_component": "GO:0005929 cilium;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0031514 motile cilium;GO:0001669 acrosomal vesicle", "go_biological_process": "GO:0007283 spermatogenesis;GO:0060271 cilium assembly;GO:0061512 protein localization to cilium;GO:2000785 regulation of autophagosome assembly;GO:0045724 positive regulation of cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LK11-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "I3LB28-1", "uniprot_id": [ { "id": "I3LB28_PIG", "url": "https://www.uniprot.org/uniprot/I3LB28", "type": "external" } ], "mass": 101865.0, "length": 910, "protein_name": "Neuropilin", "gene_name": "NRP2", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "NRP2", "gene_names_refseq": "", "protein_names_uniprotkb": "Neuropilin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-194306)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "K9IVT0", "ec_number_list": [], "go_molecular_function": "GO:0008201 heparin binding;GO:0046872 metal ion binding;GO:0017154 semaphorin receptor activity;GO:0005021 vascular endothelial growth factor receptor activity", "go_cellular_component": "GO:0016020 membrane;GO:0098978 glutamatergic synapse;GO:0005886 plasma membrane;GO:0030424 axon;GO:0045211 postsynaptic membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0007411 axon guidance;GO:0097490 sympathetic neuron projection extension;GO:0097491 sympathetic neuron projection guidance;GO:0061549 sympathetic ganglion development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LB28-1", "record_type": "protein", "filter_code": "0000000.0000101.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1SF47-1", "uniprot_id": [ { "id": "F1SF47_PIG", "url": "https://www.uniprot.org/uniprot/F1SF47", "type": "external" } ], "mass": 32121.0, "length": 292, "protein_name": "11-beta-hydroxysteroid dehydrogenase 1", "gene_name": "HSD11B1", "organism": "Pig", "refseq_name": "11-beta-hydroxysteroid dehydrogenase 1 isoform 1", "refseq_ac": [ { "id": "NP_999413", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_999413", "type": "external" } ], "gene_names_uniprotkb": "HSD11B1", "gene_names_refseq": "HSD11B1", "protein_names_uniprotkb": "11-beta-hydroxysteroid dehydrogenase 1; 1.1.1.146; 1.1.1.201; 7-oxosteroid reductase; Corticosteroid 11-beta-dehydrogenase isozyme 1", "protein_names_refseq": "11-beta hydroxysteroid dehydrogenase; 11-beta-hydroxysteroid dehydrogenase 1 isoform 1; corticosteroid 11-beta-dehydrogenase isozyme 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397480); (R-SSC-194002); (R-SSC-9757110)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "15926111;16271354;19500728;20020184;32543654", "class_list": "", "function": "Concluded that the 11beta-hydroxysteroid dehydrogenase (11beta-HSD1 and 2) system is involved in the regulation of cortisol activity in the testis and thus in the regulation of spermatogenesis, [RefSeq, PubMed]; Data show that in the testis, caput epididymidis and bulbourethral gland of the immature pig, 11betaHSD1 and 2 catalyse inactivation of cortisol, supporting a role in limiting local actions of glucocorticoids within these tissues prior to puberty., [RefSeq, PubMed]; Effects of age, weaning and/or social isolation on the expression of genes regulating HSD11B1., [RefSeq, PubMed]; Results describe the cloning, sequence and expression of 11beta-hydroxysteroid dehydrogenase type 1 from pig testis., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287AH74", "ec_number_list": [], "go_molecular_function": "GO:0070524 11-beta-hydroxysteroid dehydrogenase (NADP+) activity;GO:0047022 7-beta-hydroxysteroid dehydrogenase (NADP+) activity;GO:0042803 protein homodimerization activity;GO:0005496 steroid binding;GO:0050661 NADP binding", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006713 glucocorticoid catabolic process;GO:0006706 steroid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F1SF47-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8W4FNG1-1", "uniprot_id": [ { "id": "A0A8W4FNG1_PIG", "url": "https://www.uniprot.org/uniprot/A0A8W4FNG1", "type": "external" } ], "mass": 175252.0, "length": 1587, "protein_name": "Kinesin family member 14", "gene_name": "KIF14", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "KIF14", "gene_names_refseq": "", "protein_names_uniprotkb": "Kinesin family member 14", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity;GO:0019901 protein kinase binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005819 spindle;GO:0005874 microtubule;GO:0030496 midbody;GO:0005829 cytosol", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0007018 microtubule-based movement;GO:0021693 cerebellar Purkinje cell layer structural organization;GO:0021685 cerebellar granular layer structural organization;GO:1903429 regulation of cell maturation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FNG1-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A5G2QXK8-1", "uniprot_id": [ { "id": "A0A5G2QXK8_PIG", "url": "https://www.uniprot.org/uniprot/A0A5G2QXK8", "type": "external" } ], "mass": 36193.0, "length": 322, "protein_name": "Acyl-coenzyme A diphosphatase NUDT19", "gene_name": "NUDT19", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "NUDT19", "gene_names_refseq": "", "protein_names_uniprotkb": "Acyl-coenzyme A diphosphatase NUDT19; 3.6.1.77; Nucleoside diphosphate-linked moiety X motif 19", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-390918); (R-SSC-9033241)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched-chain fatty-acyl-CoA esters and at low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates. Highest activity seen with medium-chain acyl-CoA esters and higher rates of activity seen with the unsaturated acyl-CoA esters compared with the saturated esters. Exhibits decapping activity towards dpCoA-capped RNAs in vitro., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0046872 metal ion binding;GO:0010945 coenzyme A diphosphatase activity;GO:0000287 magnesium ion binding", "go_cellular_component": "", "go_biological_process": "GO:0036114 medium-chain fatty-acyl-CoA catabolic process;GO:2001294 malonyl-CoA catabolic process;GO:0015938 coenzyme A catabolic process;GO:0044580 butyryl-CoA catabolic process;GO:1901289 succinyl-CoA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QXK8-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "I3LGB2-1", "uniprot_id": [ { "id": "I3LGB2_PIG", "url": "https://www.uniprot.org/uniprot/I3LGB2", "type": "external" } ], "mass": 73987.0, "length": 689, "protein_name": "Proprotein convertase subtilisin/kexin type 9", "gene_name": "PCSK9", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PCSK9", "gene_names_refseq": "", "protein_names_uniprotkb": "Proprotein convertase subtilisin/kexin type 9; Proprotein convertase 9; Subtilisin/kexin-like protease PC9", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-381426); (R-SSC-8866427); (R-SSC-8957275); (R-SSC-8964038)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": [], "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0030547 signaling receptor inhibitor activity;GO:0019871 sodium channel inhibitor activity;GO:0034185 apolipoprotein binding;GO:0050750 low-density lipoprotein particle receptor binding", "go_cellular_component": "GO:0005768 endosome;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0009986 cell surface;GO:0005764 lysosome", "go_biological_process": "GO:0006508 proteolysis;GO:0008203 cholesterol metabolic process;GO:0006915 apoptotic process;GO:0001889 liver development;GO:0032869 cellular response to insulin stimulus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LGB2-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A5G2RE65-1", "uniprot_id": [ { "id": "A0A5G2RE65_PIG", "url": "https://www.uniprot.org/uniprot/A0A5G2RE65", "type": "external" } ], "mass": 227615.0, "length": 2019, "protein_name": "Sodium channel protein", "gene_name": "SCN5A", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "SCN5A", "gene_names_refseq": "", "protein_names_uniprotkb": "Sodium channel protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, 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sodium channel complex;GO:0030424 axon", "go_biological_process": "GO:0048731 system development;GO:0002027 regulation of heart rate;GO:0048513 animal organ development;GO:0090257 regulation of muscle system process;GO:0098719 sodium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2RE65-1", "record_type": "protein", "filter_code": "0000000.0000100.010000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1RMJ1-1", "uniprot_id": [ { "id": "F1RMJ1_PIG", "url": "https://www.uniprot.org/uniprot/F1RMJ1", "type": "external" } ], "mass": 87245.0, "length": 797, "protein_name": "Furin", "gene_name": "FURIN", "organism": "Pig", "refseq_name": "furin isoform X2", "refseq_ac": [ { "id": "XP_001929382", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001929382", "type": "external" } ], "gene_names_uniprotkb": "FURIN", "gene_names_refseq": "FURIN", "protein_names_uniprotkb": "Furin; 3.4.21.75; 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"go_biological_process": "GO:0016485 protein processing;GO:0019058 viral life cycle;GO:0032902 nerve growth factor production;GO:0090472 dibasic protein processing;GO:0016486 peptide hormone processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RMJ1-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000001000.001.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1SPM9-1", "uniprot_id": [ { "id": "F1SPM9_PIG", "url": "https://www.uniprot.org/uniprot/F1SPM9", "type": "external" } ], "mass": 42900.0, "length": 389, "protein_name": "Protein Wnt", "gene_name": "WNT10B", "organism": "Pig", "refseq_name": "protein Wnt-10b isoform X1", "refseq_ac": [ { "id": "XP_020946517", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020946517", "type": "external" } ], "gene_names_uniprotkb": "WNT10B", "gene_names_refseq": "WNT10B", "protein_names_uniprotkb": "Protein Wnt", "protein_names_refseq": "protein Wnt-10b isoform X1", 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"0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "A0A8D1VS88-1", "uniprot_id": [ { "id": "A0A8D1VS88_PIG", "url": "https://www.uniprot.org/uniprot/A0A8D1VS88", "type": "external" } ], "mass": 93885.0, "length": 838, "protein_name": "Tyrosine-protein kinase receptor", "gene_name": "NTRK2", "organism": "Pig", "refseq_name": "BDNF/NT-3 growth factors receptor isoform X1", "refseq_ac": [ { "id": "XP_020920301", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_020920301", "type": "external" } ], "gene_names_uniprotkb": "NTRK2", "gene_names_refseq": "NTRK2", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor; 2.7.10.1", "protein_names_refseq": "BDNF/NT-3 growth factors receptor isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100519209); (R-SSC-1257604); (R-SSC-6811558); (R-SSC-9026527); (R-SSC-9028731); (R-SSC-9032759)", "pathway_count": 6, "publication_count": 1, "publication_id_list": 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10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287A6X2", "ec_number_list": [], "go_molecular_function": "GO:0005524 ATP binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity;GO:0005030 neurotrophin receptor activity;GO:0060175 brain-derived neurotrophic factor receptor activity;GO:0002020 protease binding", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0005829 cytosol;GO:0014069 postsynaptic density;GO:0030424 axon", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:1990416 cellular response to brain-derived neurotrophic factor stimulus;GO:0007612 learning;GO:0010628 positive regulation of gene expression;GO:0010976 positive regulation of neuron projection development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8D1VS88-1", "record_type": "protein", "filter_code": "0000000.0000101.100000.000000000000010000.0000000000000.000.00000", "kg_view_protein": true }, { "uniprot_canonical_ac": "F1SAI0-1", "uniprot_id": [ { "id": "F1SAI0_PIG", "url": "https://www.uniprot.org/uniprot/F1SAI0", "type": "external" } ], "mass": 98805.0, "length": 863, "protein_name": "Phosphatidylinositol 3-kinase catalytic subunit type 3", "gene_name": "PIK3C3", "organism": "Pig", "refseq_name": "", "refseq_ac": [], "gene_names_uniprotkb": "PIK3C3", "gene_names_refseq": "", "protein_names_uniprotkb": "Phosphatidylinositol 3-kinase catalytic subunit type 3; 2.7.1.137", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-109704); (R-SSC-1632852); (R-SSC-1660514); (R-SSC-1660516); (R-SSC-1660517); (R-SSC-168138); (R-SSC-5668599)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. As part of PI3KC3-C1, promotes endoplasmic reticulum membrane curvature formation prior to vesicle budding. Involved in regulation of degradative endocytic trafficking and required for the abscission step in cytokinesis, probably in the context of PI3KC3-C2. Involved in the transport of lysosomal enzyme precursors to lysosomes. 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This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. 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